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Conserved domains on  [gi|1034585096|ref|XP_016876287|]
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protein O-mannosyl-transferase TMTC4 isoform X5 [Homo sapiens]

Protein Classification

DUF1736 and TPR domain-containing protein( domain architecture ID 12091460)

DUF1736 and TPR domain-containing protein

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
DUF1736 pfam08409
Domain of unknown function (DUF1736); This domain of unknown function is found in various ...
75-149 3.44e-40

Domain of unknown function (DUF1736); This domain of unknown function is found in various hypothetical metazoan proteins.


:

Pssm-ID: 429980  Cd Length: 75  Bit Score: 139.59  E-value: 3.44e-40
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1034585096  75 GTGPPAFTEVDNPASFADSMLVRAVNYNYYYSLNAWLLLCPWWLCFDWSMGCIPLIKSISDWRVIALAALWFCLI 149
Cdd:pfam08409   1 GGQLPVFSESDNPAAFSPSLLTRTLTYNYLPALNAWLLLCPSWLCFDWSMGSIPLIESLLDPRNLATLAFYGALA 75
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
264-500 7.02e-15

Tetratricopeptide (TPR) repeat [General function prediction only];


:

Pssm-ID: 223533 [Multi-domain]  Cd Length: 291  Bit Score: 75.27  E-value: 7.02e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585096 264 NAKVHYNIGKNLADKGNQTAAIRYYREAVRLNPKYVHAM--NNLGNILKERNELQEAEELL--SLAVQIQPDFAAAWMNL 339
Cdd:COG0457    22 ALALLEAGLALLELLGELAEALELLEEALELLPNSDLAGllLLLALALLKLGRLEEALELLekALELELLPNLAEALLNL 101
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585096 340 GIVQNSLKRFEAAEQSYRTAIKHRRKYPDCYYNLGR-LYADLNRHVDALNAWRNATVLKPEHS---LAWNNMIILLDNTG 415
Cdd:COG0457   102 GLLLEALGKYEEALELLEKALALDPDPDLAEALLALgALYELGDYEEALELYEKALELDPELNelaEALLALGALLEALG 181
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585096 416 NLAQAEAVGREALELIPN-DHSLMFSLANVLGKSQKYKESEALFLKAIKANPNAASYHGNLAVLYHRWGHLDLAKKHYEI 494
Cdd:COG0457   182 RYEEALELLEKALKLNPDdDAEALLNLGLLYLKLGKYEEALEYYEKALELDPDNAEALYNLALLLLELGRYEEALEALEK 261

                  ....*.
gi 1034585096 495 SLQLDP 500
Cdd:COG0457   262 ALELDP 267
 
Name Accession Description Interval E-value
DUF1736 pfam08409
Domain of unknown function (DUF1736); This domain of unknown function is found in various ...
75-149 3.44e-40

Domain of unknown function (DUF1736); This domain of unknown function is found in various hypothetical metazoan proteins.


Pssm-ID: 429980  Cd Length: 75  Bit Score: 139.59  E-value: 3.44e-40
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1034585096  75 GTGPPAFTEVDNPASFADSMLVRAVNYNYYYSLNAWLLLCPWWLCFDWSMGCIPLIKSISDWRVIALAALWFCLI 149
Cdd:pfam08409   1 GGQLPVFSESDNPAAFSPSLLTRTLTYNYLPALNAWLLLCPSWLCFDWSMGSIPLIESLLDPRNLATLAFYGALA 75
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
264-500 7.02e-15

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 223533 [Multi-domain]  Cd Length: 291  Bit Score: 75.27  E-value: 7.02e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585096 264 NAKVHYNIGKNLADKGNQTAAIRYYREAVRLNPKYVHAM--NNLGNILKERNELQEAEELL--SLAVQIQPDFAAAWMNL 339
Cdd:COG0457    22 ALALLEAGLALLELLGELAEALELLEEALELLPNSDLAGllLLLALALLKLGRLEEALELLekALELELLPNLAEALLNL 101
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585096 340 GIVQNSLKRFEAAEQSYRTAIKHRRKYPDCYYNLGR-LYADLNRHVDALNAWRNATVLKPEHS---LAWNNMIILLDNTG 415
Cdd:COG0457   102 GLLLEALGKYEEALELLEKALALDPDPDLAEALLALgALYELGDYEEALELYEKALELDPELNelaEALLALGALLEALG 181
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585096 416 NLAQAEAVGREALELIPN-DHSLMFSLANVLGKSQKYKESEALFLKAIKANPNAASYHGNLAVLYHRWGHLDLAKKHYEI 494
Cdd:COG0457   182 RYEEALELLEKALKLNPDdDAEALLNLGLLYLKLGKYEEALEYYEKALELDPDNAEALYNLALLLLELGRYEEALEALEK 261

                  ....*.
gi 1034585096 495 SLQLDP 500
Cdd:COG0457   262 ALELDP 267
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
252-500 9.52e-15

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 77.43  E-value: 9.52e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585096 252 QLFRSALSVCPLNAKVHYNIGKNLADKGNQTAAIRYYREAVRLNPKYVHAMNNLGNILKERNELQEAEELLSLAVQIQPD 331
Cdd:TIGR02917 520 QRFEKVLTIDPKNLRAILALAGLYLRTGNEEEAVAWLEKAAELNPQEIEPALALAQYYLGKGQLKKALAILNEAADAAPD 599
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585096 332 FAAAWMNLGIVQNSLKRFEAAEQSYRTAIKHRRKYPDCYYNLGRLYADLNRHVDALNAWRNATVLKPEHSLAWNNMIILL 411
Cdd:TIGR02917 600 SPEAWLMLGRAQLAAGDLNKAVSSFKKLLALQPDSALALLLLADAYAVMKNYAKAITSLKRALELKPDNTEAQIGLAQLL 679
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585096 412 DNT----------------------------------GNLAQAEAVGREALELIPNDHSLMfSLANVLGKSQKYKESEAL 457
Cdd:TIGR02917 680 LAAkrtesakkiakslqkqhpkaalgfelegdlylrqKDYPAAIQAYRKALKRAPSSQNAI-KLHRALLASGNTAEAVKT 758
                         250       260       270       280
                  ....*....|....*....|....*....|....*....|...
gi 1034585096 458 FLKAIKANPNAASYHGNLAVLYHRWGHLDLAKKHYEISLQLDP 500
Cdd:TIGR02917 759 LEAWLKTHPNDAVLRTALAELYLAQKDYDKAIKHYQTVVKKAP 801
C39_PA2778_fam NF033920
PA2778 family cysteine peptidase; Members of this family are MEROPS classification C39 family ...
279-361 4.67e-09

PA2778 family cysteine peptidase; Members of this family are MEROPS classification C39 family cysteine peptidases, a group that includes many processing enzyme for peptide natural products such as lantibiotics and other bacteriocins. This family, more specifically, includes PA2778 as found in Pseudomonas aeruginosa. All members of the defining seed alignment are encoded in the vicinity of a homolog of PA2779 (see HMM NF033919). Note that the C-terminal region consists largely of tetratricopeptide repeats (TPR), so classification using this HMM must be based on comparing the top domain score to the second gathering threshold (GA2).


Pssm-ID: 411481 [Multi-domain]  Cd Length: 255  Bit Score: 57.17  E-value: 4.67e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585096 279 GNQTAAIRYYREAVRLNPKYVHAMNNLGNILKERNELQEAEELLSLAVQIQPDFAAAWMNLGIVQNSLKRFEAAEQSYRT 358
Cdd:NF033920  170 GQPEAALAAYQTATKRWPDSWLAYFGLGNAAYAAGDYAAAAAAFRQAVERHPDSAAAWNNLAYALAAQGCTAQARAAAEC 249

                  ...
gi 1034585096 359 AIK 361
Cdd:NF033920  250 ALA 252
PRK02603 PRK02603
photosystem I assembly protein Ycf3; Provisional
267-327 1.17e-06

photosystem I assembly protein Ycf3; Provisional


Pssm-ID: 179448 [Multi-domain]  Cd Length: 172  Bit Score: 48.51  E-value: 1.17e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1034585096 267 VHYNIGKNLADKGNQTAAIRYYREAVRLNPKYVHAMNNLGNIL-------KERNELQEAEELLSLAVQ 327
Cdd:PRK02603   74 ILYNMGIIYASNGEHDKALEYYHQALELNPKQPSALNNIAVIYhkrgekaEEAGDQDEAEALFDKAAE 141
C39_PA2778_fam NF033920
PA2778 family cysteine peptidase; Members of this family are MEROPS classification C39 family ...
382-500 5.52e-06

PA2778 family cysteine peptidase; Members of this family are MEROPS classification C39 family cysteine peptidases, a group that includes many processing enzyme for peptide natural products such as lantibiotics and other bacteriocins. This family, more specifically, includes PA2778 as found in Pseudomonas aeruginosa. All members of the defining seed alignment are encoded in the vicinity of a homolog of PA2779 (see HMM NF033919). Note that the C-terminal region consists largely of tetratricopeptide repeats (TPR), so classification using this HMM must be based on comparing the top domain score to the second gathering threshold (GA2).


Pssm-ID: 411481 [Multi-domain]  Cd Length: 255  Bit Score: 47.93  E-value: 5.52e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585096 382 RHVDALNA----WRNA-----TVLKPEHS------LAWNNMIILLDNTGNLAQAEAVGREALELIPNDHSLMFSLANVLG 446
Cdd:NF033920  122 RHRLSFSTfertWARAdywalVVLPPGQLpatadpLAYLRAAQDLEQTGQPEAALAAYQTATKRWPDSWLAYFGLGNAAY 201
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1034585096 447 KSQKYKESEALFLKAIKANPNAASYHGNLAVLYHRWGHLDLAKKHYEISLQLDP 500
Cdd:NF033920  202 AAGDYAAAAAAFRQAVERHPDSAAAWNNLAYALAAQGCTAQARAAAECALALAP 255
TPR_19 pfam14559
Tetratricopeptide repeat;
279-337 6.06e-06

Tetratricopeptide repeat;


Pssm-ID: 434038 [Multi-domain]  Cd Length: 65  Bit Score: 43.73  E-value: 6.06e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1034585096 279 GNQTAAIRYYREAVRLNPKYVHAMNNLGNILKERNELQEAEELLSLAVQIQPDFAAAWM 337
Cdd:pfam14559   2 GDYAEALELLEQALAEDPDNAEARLGLAEALLALGRLDEAEALLAALPAADPDDPRYAA 60
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
333-366 2.85e-03

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 35.50  E-value: 2.85e-03
                           10        20        30
                   ....*....|....*....|....*....|....
gi 1034585096  333 AAAWMNLGIVQNSLKRFEAAEQSYRTAIKHRRKY 366
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
 
Name Accession Description Interval E-value
DUF1736 pfam08409
Domain of unknown function (DUF1736); This domain of unknown function is found in various ...
75-149 3.44e-40

Domain of unknown function (DUF1736); This domain of unknown function is found in various hypothetical metazoan proteins.


Pssm-ID: 429980  Cd Length: 75  Bit Score: 139.59  E-value: 3.44e-40
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1034585096  75 GTGPPAFTEVDNPASFADSMLVRAVNYNYYYSLNAWLLLCPWWLCFDWSMGCIPLIKSISDWRVIALAALWFCLI 149
Cdd:pfam08409   1 GGQLPVFSESDNPAAFSPSLLTRTLTYNYLPALNAWLLLCPSWLCFDWSMGSIPLIESLLDPRNLATLAFYGALA 75
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
264-500 7.02e-15

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 223533 [Multi-domain]  Cd Length: 291  Bit Score: 75.27  E-value: 7.02e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585096 264 NAKVHYNIGKNLADKGNQTAAIRYYREAVRLNPKYVHAM--NNLGNILKERNELQEAEELL--SLAVQIQPDFAAAWMNL 339
Cdd:COG0457    22 ALALLEAGLALLELLGELAEALELLEEALELLPNSDLAGllLLLALALLKLGRLEEALELLekALELELLPNLAEALLNL 101
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585096 340 GIVQNSLKRFEAAEQSYRTAIKHRRKYPDCYYNLGR-LYADLNRHVDALNAWRNATVLKPEHS---LAWNNMIILLDNTG 415
Cdd:COG0457   102 GLLLEALGKYEEALELLEKALALDPDPDLAEALLALgALYELGDYEEALELYEKALELDPELNelaEALLALGALLEALG 181
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585096 416 NLAQAEAVGREALELIPN-DHSLMFSLANVLGKSQKYKESEALFLKAIKANPNAASYHGNLAVLYHRWGHLDLAKKHYEI 494
Cdd:COG0457   182 RYEEALELLEKALKLNPDdDAEALLNLGLLYLKLGKYEEALEYYEKALELDPDNAEALYNLALLLLELGRYEEALEALEK 261

                  ....*.
gi 1034585096 495 SLQLDP 500
Cdd:COG0457   262 ALELDP 267
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
252-500 9.52e-15

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 77.43  E-value: 9.52e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585096 252 QLFRSALSVCPLNAKVHYNIGKNLADKGNQTAAIRYYREAVRLNPKYVHAMNNLGNILKERNELQEAEELLSLAVQIQPD 331
Cdd:TIGR02917 520 QRFEKVLTIDPKNLRAILALAGLYLRTGNEEEAVAWLEKAAELNPQEIEPALALAQYYLGKGQLKKALAILNEAADAAPD 599
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585096 332 FAAAWMNLGIVQNSLKRFEAAEQSYRTAIKHRRKYPDCYYNLGRLYADLNRHVDALNAWRNATVLKPEHSLAWNNMIILL 411
Cdd:TIGR02917 600 SPEAWLMLGRAQLAAGDLNKAVSSFKKLLALQPDSALALLLLADAYAVMKNYAKAITSLKRALELKPDNTEAQIGLAQLL 679
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585096 412 DNT----------------------------------GNLAQAEAVGREALELIPNDHSLMfSLANVLGKSQKYKESEAL 457
Cdd:TIGR02917 680 LAAkrtesakkiakslqkqhpkaalgfelegdlylrqKDYPAAIQAYRKALKRAPSSQNAI-KLHRALLASGNTAEAVKT 758
                         250       260       270       280
                  ....*....|....*....|....*....|....*....|...
gi 1034585096 458 FLKAIKANPNAASYHGNLAVLYHRWGHLDLAKKHYEISLQLDP 500
Cdd:TIGR02917 759 LEAWLKTHPNDAVLRTALAELYLAQKDYDKAIKHYQTVVKKAP 801
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
264-496 4.49e-14

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 223533 [Multi-domain]  Cd Length: 291  Bit Score: 72.96  E-value: 4.49e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585096 264 NAKVHYNIGKNLADKGNQTAAIRYYREAVR--LNPKYVHAMNNLGNILKERNELQEAEELLSLAVQIQPDFAAAWMNLGI 341
Cdd:COG0457    58 LAGLLLLLALALLKLGRLEEALELLEKALEleLLPNLAEALLNLGLLLEALGKYEEALELLEKALALDPDPDLAEALLAL 137
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585096 342 -VQNSLKRFEAAEQSYRTAIK---HRRKYPDCYYNLGRLYADLNRHVDALNAWRNATVLKPEHSL-AWNNMIILLDNTGN 416
Cdd:COG0457   138 gALYELGDYEEALELYEKALEldpELNELAEALLALGALLEALGRYEEALELLEKALKLNPDDDAeALLNLGLLYLKLGK 217
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585096 417 LAQAEAVGREALELIPNDHSLMFSLANVLGKSQKYKESEALFLKAIKANPNaasyHGNLAVLYhrWGHLDLAKKHYEISL 496
Cdd:COG0457   218 YEEALEYYEKALELDPDNAEALYNLALLLLELGRYEEALEALEKALELDPD----LYNLGLAL--LLLLAEALELLEKAD 291
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
254-490 2.25e-13

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 72.81  E-value: 2.25e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585096 254 FRSALSVCPLNAKVHYNIGKNLADKGNQTAAIRYYREAVRLNPKYVHAMNNLGNILKERNELQEAEELLSLAVQIQPDFA 333
Cdd:TIGR02917 624 FKKLLALQPDSALALLLLADAYAVMKNYAKAITSLKRALELKPDNTEAQIGLAQLLLAAKRTESAKKIAKSLQKQHPKAA 703
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585096 334 AAWMNLGIVQNSLKRFEAAEQSYRTAIK-----------HR-------------------RKYPD---CYYNLGRLYADL 380
Cdd:TIGR02917 704 LGFELEGDLYLRQKDYPAAIQAYRKALKrapssqnaiklHRallasgntaeavktleawlKTHPNdavLRTALAELYLAQ 783
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585096 381 NRHVDALNAWRNATVLKPEHSLAWNNMIILLDNTGNlAQAEAVGREALELIPNDHSLMFSLANVLGKSQKYKESEALFLK 460
Cdd:TIGR02917 784 KDYDKAIKHYQTVVKKAPDNAVVLNNLAWLYLELKD-PRALEYAERALKLAPNIPAILDTLGWLLVEKGEADRALPLLRK 862
                         250       260       270
                  ....*....|....*....|....*....|
gi 1034585096 461 AIKANPNAASYHGNLAVLYHRWGHLDLAKK 490
Cdd:TIGR02917 863 AVNIAPEAAAIRYHLALALLATGRKAEARK 892
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
281-521 2.88e-13

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 223533 [Multi-domain]  Cd Length: 291  Bit Score: 70.26  E-value: 2.88e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585096 281 QTAAIRYYREAVRLNPKYVHAMNNLGNILKERNELQEAEELLSLAVQIQP--DFAAAWMNLGIVQNSLKRFEAAEQSYRT 358
Cdd:COG0457     5 LLALAILLEALAKLLAEALALLEAGLALLELLGELAEALELLEEALELLPnsDLAGLLLLLALALLKLGRLEEALELLEK 84
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585096 359 AIKHR--RKYPDCYYNLGRLYADLNRHVDALNAWRNATVLKPEHSLAWNNM-IILLDNTGNLAQAEAVGREALELIPNDH 435
Cdd:COG0457    85 ALELEllPNLAEALLNLGLLLEALGKYEEALELLEKALALDPDPDLAEALLaLGALYELGDYEEALELYEKALELDPELN 164
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585096 436 SL---MFSLANVLGKSQKYKESEALFLKAIKANPN-AASYHGNLAVLYHRWGHLDLAKKHYEISLQLDPTASGTKENYGL 511
Cdd:COG0457   165 ELaeaLLALGALLEALGRYEEALELLEKALKLNPDdDAEALLNLGLLYLKLGKYEEALEYYEKALELDPDNAEALYNLAL 244
                         250
                  ....*....|
gi 1034585096 512 LRRKLELMQK 521
Cdd:COG0457   245 LLLELGRYEE 254
type_IV_pilW TIGR02521
type IV pilus biogenesis/stability protein PilW; Members of this family are designated PilF ...
257-389 1.96e-12

type IV pilus biogenesis/stability protein PilW; Members of this family are designated PilF and PilW. This outer membrane protein is required both for pilus stability and for pilus function such as adherence to human cells. Members of this family contain copies of the TPR (tetratricopeptide repeat) domain.


Pssm-ID: 131573 [Multi-domain]  Cd Length: 234  Bit Score: 66.98  E-value: 1.96e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585096 257 ALSVCPLNAKVHYNIGKNLADKGNQTAAIRYYREAVRLNPKYVHAMNNLGNILKERNELQEAEELLSLAVQiQPDF---A 333
Cdd:TIGR02521  57 ALEHDPDDYLAYLALALYYQQLGELEKAEDSFRRALTLNPNNGDVLNNYGTFLCQQGKYEQAMQQFEQAIE-DPLYpqpA 135
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1034585096 334 AAWMNLGIVQNSLKRFEAAEQSYRTAIKHRRKYPDCYYNLGRLYADLNRHVDALNA 389
Cdd:TIGR02521 136 RSLENAGLCALKAGDFDKAEKYLTRALQIDPQRPESLLELAELYYLRGQYKDARAY 191
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
278-500 2.37e-12

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 69.73  E-value: 2.37e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585096 278 KGNQTAAIRYYREAVRLNPKYVHAMNNLGNILKERNELQEAEELLSLAVQIQPDFAAAWMNLGIVQNSLKRFEAAEQSYR 357
Cdd:TIGR02917 138 LGQLELAQKSYEQALAIDPRSLYAKLGLAQLALAENRFDEARALIDEVLTADPGNVDALLLKGDLLLSLGNIELALAAYR 217
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585096 358 TAIKHRRKYPDCYYNLGRLYADLNR------HVDALNAWRN----ATVLKP-------------EH-----SLAWNNMII 409
Cdd:TIGR02917 218 KAIALRPNNIAVLLALATILIEAGEfeeaekHADALLKKAPnsplAHYLKAlvdfqkknyedarETlqdalKSAPEYLPA 297
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585096 410 LL------DNTGNLAQAEAVGREALELIPNDHSLMFSLANVLGKSQKYKESEALFLKAIKANPNAASYHGNLAVLYHRWG 483
Cdd:TIGR02917 298 LLlagaseYQLGNLEQAYQYLNQILKYAPNSHQARRLLASIQLRLGRVDEAIATLSPALGLDPDDPAALSLLGEAYLALG 377
                         250
                  ....*....|....*..
gi 1034585096 484 HLDLAKKHYEISLQLDP 500
Cdd:TIGR02917 378 DFEKAAEYLAKATELDP 394
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
251-500 7.24e-12

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 68.19  E-value: 7.24e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585096 251 EQLFRSALSVCPLNAKVHYNIGKNLADKGNQTAAIRYYREAVRLNPKYVHAMNNLGNILKERNELQEAEELLSLAVQIQP 330
Cdd:TIGR02917 179 RALIDEVLTADPGNVDALLLKGDLLLSLGNIELALAAYRKAIALRPNNIAVLLALATILIEAGEFEEAEKHADALLKKAP 258
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585096 331 DFAAAWMNLGIVQNSLKRFEAAEQSYRTAIKHRRKYPDCYYNLGRLYADLNRHVDALnAWRNATVLKPEHSLAWNNMI-- 408
Cdd:TIGR02917 259 NSPLAHYLKALVDFQKKNYEDARETLQDALKSAPEYLPALLLAGASEYQLGNLEQAY-QYLNQILKYAPNSHQARRLLas 337
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585096 409 ILLDNtGNLAQAEAVGREALELIPNDHSLMFSLANVLGKSQKYKESEALFLKAIKANPNAASYHGNLAVLYHRWGHLDLA 488
Cdd:TIGR02917 338 IQLRL-GRVDEAIATLSPALGLDPDDPAALSLLGEAYLALGDFEKAAEYLAKATELDPENAAARTQLGISKLSQGDPSEA 416
                         250
                  ....*....|..
gi 1034585096 489 KKHYEISLQLDP 500
Cdd:TIGR02917 417 IADLETAAQLDP 428
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
245-502 9.39e-12

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 67.80  E-value: 9.39e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585096 245 GEWRSEEQLFRSALSVCPLNakvhYNIGKNLA----DKGNQTAAIRYYREAVRLNPKYVHAMNNLGNILKERNELQEAEE 320
Cdd:TIGR02917 309 GNLEQAYQYLNQILKYAPNS----HQARRLLAsiqlRLGRVDEAIATLSPALGLDPDDPAALSLLGEAYLALGDFEKAAE 384
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585096 321 LLSLAVQIQPDFAAAWMNLGIVQNSLKRFEAAEQSYRTAIKHRRKYPDCYYNLGRLYADLNRHVDALNAWRNATVLKPEH 400
Cdd:TIGR02917 385 YLAKATELDPENAAARTQLGISKLSQGDPSEAIADLETAAQLDPELGRADLLLILSYLRSGQFDKALAAAKKLEKKQPDN 464
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585096 401 SLAWNNMIILLDNTGNLAQAEAVGREALELIPNDHSLMFSLANVLGKSQKYKESEALFLKAIKANPNAASYHGNLAVLYH 480
Cdd:TIGR02917 465 ASLHNLLGAIYLGKGDLAKAREAFEKALSIEPDFFPAAANLARIDIQEGNPDDAIQRFEKVLTIDPKNLRAILALAGLYL 544
                         250       260
                  ....*....|....*....|..
gi 1034585096 481 RWGHLDLAKKHYEISLQLDPTA 502
Cdd:TIGR02917 545 RTGNEEEAVAWLEKAAELNPQE 566
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
256-500 1.06e-11

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 67.42  E-value: 1.06e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585096 256 SALSVCPLN-AKVHYNIGKNLADKGNQTAAIRYYREAVRLNPKYVHAMNNLGNILKERNELQEAEELLSLAV-------Q 327
Cdd:TIGR02917  12 LALSACGDQsPEELIEAAKSYLQKNKYKAAIIQLKNALQKDPNDAEARFLLGKIYLALGDYAAAEKELRKALslgypknQ 91
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585096 328 IQPDFAAAWMNLGIVQNSL----------------------------KRFEAAEQSYRTAIKHRRKYPDCYYNLGRLYAD 379
Cdd:TIGR02917  92 VLPLLARAYLLQGKFQQVLdelpgktllddegaaellalrglaylglGQLELAQKSYEQALAIDPRSLYAKLGLAQLALA 171
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585096 380 LNRHVDALNAWRNATVLKPEHSLAWNNMIILLDNTGNLAQAEAVGREALELIPNDHSLMFSLANVLGKSQKYKESEALFL 459
Cdd:TIGR02917 172 ENRFDEARALIDEVLTADPGNVDALLLKGDLLLSLGNIELALAAYRKAIALRPNNIAVLLALATILIEAGEFEEAEKHAD 251
                         250       260       270       280
                  ....*....|....*....|....*....|....*....|.
gi 1034585096 460 KAIKANPNAASYHGNLAVLYHRWGHLDLAKKHYEISLQLDP 500
Cdd:TIGR02917 252 ALLKKAPNSPLAHYLKALVDFQKKNYEDARETLQDALKSAP 292
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
230-400 2.15e-10

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 223533 [Multi-domain]  Cd Length: 291  Bit Score: 61.79  E-value: 2.15e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585096 230 LGILFINTLRCVLRSGEWRSEEQLFRSALSVCPLNAKVHYNIGKN-LADKGNQTAAIRYYREAVRLNPK---YVHAMNNL 305
Cdd:COG0457    94 LAEALLNLGLLLEALGKYEEALELLEKALALDPDPDLAEALLALGaLYELGDYEEALELYEKALELDPElneLAEALLAL 173
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585096 306 GNILKERNELQEAEELLSLAVQIQPDFAA-AWMNLGIVQNSLKRFEAAEQSYRTAIKHRRKYPDCYYNLGRLYADLNRHV 384
Cdd:COG0457   174 GALLEALGRYEEALELLEKALKLNPDDDAeALLNLGLLYLKLGKYEEALEYYEKALELDPDNAEALYNLALLLLELGRYE 253
                         170
                  ....*....|....*.
gi 1034585096 385 DALNAWRNATVLKPEH 400
Cdd:COG0457   254 EALEALEKALELDPDL 269
C39_PA2778_fam NF033920
PA2778 family cysteine peptidase; Members of this family are MEROPS classification C39 family ...
279-361 4.67e-09

PA2778 family cysteine peptidase; Members of this family are MEROPS classification C39 family cysteine peptidases, a group that includes many processing enzyme for peptide natural products such as lantibiotics and other bacteriocins. This family, more specifically, includes PA2778 as found in Pseudomonas aeruginosa. All members of the defining seed alignment are encoded in the vicinity of a homolog of PA2779 (see HMM NF033919). Note that the C-terminal region consists largely of tetratricopeptide repeats (TPR), so classification using this HMM must be based on comparing the top domain score to the second gathering threshold (GA2).


Pssm-ID: 411481 [Multi-domain]  Cd Length: 255  Bit Score: 57.17  E-value: 4.67e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585096 279 GNQTAAIRYYREAVRLNPKYVHAMNNLGNILKERNELQEAEELLSLAVQIQPDFAAAWMNLGIVQNSLKRFEAAEQSYRT 358
Cdd:NF033920  170 GQPEAALAAYQTATKRWPDSWLAYFGLGNAAYAAGDYAAAAAAFRQAVERHPDSAAAWNNLAYALAAQGCTAQARAAAEC 249

                  ...
gi 1034585096 359 AIK 361
Cdd:NF033920  250 ALA 252
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
269-457 1.11e-08

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 227343 [Multi-domain]  Cd Length: 257  Bit Score: 55.90  E-value: 1.11e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585096 269 YNIGKNLADKGNQTAAIRYYREAVRLNPKYVHAMNNLGNILKERNELQEAEELLSLAVQIQPDFAAAWMNLGIVQNSLKR 348
Cdd:COG5010    70 AKLATALYLRGDADSSLAVLQKSAIAYPKDRELLAAQGKNQIRNGNFGEAVSVLRKAARLAPTDWEAWNLLGAALDQLGR 149
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585096 349 FEAAEQSYRTAIKhrrkypdcyynlgrlyadlnrhvdalnawrnatvLKPEHSLAWNNMIILLDNTGNLAQAEAVGREAL 428
Cdd:COG5010   150 FDEARRAYRQALE----------------------------------LAPNEPSIANNLGMSLLLRGDLEDAETLLLPAY 195
                         170       180
                  ....*....|....*....|....*....
gi 1034585096 429 ELIPNDHSLMFSLANVLGKSQKYKESEAL 457
Cdd:COG5010   196 LSPAADSRVRQNLALVVGLQGDFREAEDI 224
PilF COG3063
Tfp pilus assembly protein PilF [Cell motility, Extracellular structures];
242-386 1.37e-08

Tfp pilus assembly protein PilF [Cell motility, Extracellular structures];


Pssm-ID: 225605 [Multi-domain]  Cd Length: 250  Bit Score: 55.51  E-value: 1.37e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585096 242 LRSGEWRSEEQLFRSALSVCPLNAKVHYNIGKNLADKGNQTAAIRYYREAVRLNPKYVHAMNNLGNILKERNELQEAEEL 321
Cdd:COG3063    46 LQQGDYAQAKKNLEKALEHDPSYYLAHLVRAHYYQKLGENDLADESYRKALSLAPNNGDVLNNYGAFLCAQGRPEEAMQQ 125
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1034585096 322 LSLAVQiQPDF---AAAWMNLGIVQNSLKRFEAAEQSYRTAIKHRRKYPDCYYNLGRLYADLNRHVDA 386
Cdd:COG3063   126 FERALA-DPAYgepSDTLENLGLCALKAGQFDQAEEYLKRALELDPQFPPALLELARLHYKAGDYAPA 192
PilF COG3063
Tfp pilus assembly protein PilF [Cell motility, Extracellular structures];
311-470 2.00e-08

Tfp pilus assembly protein PilF [Cell motility, Extracellular structures];


Pssm-ID: 225605 [Multi-domain]  Cd Length: 250  Bit Score: 55.12  E-value: 2.00e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585096 311 ERNELQEAEELLSLAVQIQPDFAAAWMNLGIVQNSLKRFEAAEQSYRTAIKHRRKYPDCYYNLGRLYADLNRHVDALNAW 390
Cdd:COG3063    47 QQGDYAQAKKNLEKALEHDPSYYLAHLVRAHYYQKLGENDLADESYRKALSLAPNNGDVLNNYGAFLCAQGRPEEAMQQF 126
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585096 391 RNATVLK--PEHSLAWNNMIILLDNTGNLAQAEAVGREALELIPNDHSLMFSLANVLGKSQKYKESEALFLK-AIKANPN 467
Cdd:COG3063   127 ERALADPayGEPSDTLENLGLCALKAGQFDQAEEYLKRALELDPQFPPALLELARLHYKAGDYAPARLYLERyQQRGGAQ 206

                  ...
gi 1034585096 468 AAS 470
Cdd:COG3063   207 AES 209
YfgC COG4783
Putative Zn-dependent protease, contains TPR repeats [General function prediction only];
289-389 3.38e-08

Putative Zn-dependent protease, contains TPR repeats [General function prediction only];


Pssm-ID: 227122 [Multi-domain]  Cd Length: 484  Bit Score: 55.87  E-value: 3.38e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585096 289 REAVRLNPKYVHAMNNLGNILKERNELQEAEELLSLAVQIQPDFAAAWMNLGIVQNSLKRFEAAEQSYRTAIKHRRKYPD 368
Cdd:COG4783   330 QPLIAAQPDNPYYLELAGDILLEANKAKEAIERLKKALALDPNSPLLQLNLAQALLKGGKPQEAIRILNRYLFNDPEDPN 409
                          90       100
                  ....*....|....*....|.
gi 1034585096 369 CYYNLGRLYADLNRHVDALNA 389
Cdd:COG4783   410 GWDLLAQAYAELGNRAEALLA 430
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
276-524 9.89e-08

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 54.60  E-value: 9.89e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585096 276 ADKGNQTAAIRYYREAVRLNPKYVHAMNNLGNILKERNELQEAEELLSLAVQIQPDFAAAWMNLGIVQNSLKRFEAAEQS 355
Cdd:TIGR00990 376 LELGDPDKAEEDFDKALKLNSEDPDIYYHRAQLHFIKGEFAQAGKDYQKSIDLDPDFIFSHIQLGVTQYKEGSIASSMAT 455
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585096 356 YRTAIKHRRKYPDCYYNLGRLYADLNRHVDALNAWRNATVLKPEHSLAWNNMIILLDNTGNLAQAEavgrealelipndh 435
Cdd:TIGR00990 456 FRRCKKNFPEAPDVYNYYGELLLDQNKFDEAIEKFDTAIELEKETKPMYMNVLPLINKALALFQWK-------------- 521
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585096 436 slmfslanvlgksQKYKESEALFLKAIKANPNAASYHGNLAVLYHRWGHLDLAKKHYEISLQLDPT----------ASGT 505
Cdd:TIGR00990 522 -------------QDFIEAENLCEKALIIDPECDIAVATMAQLLLQQGDVDEALKLFERAAELARTegelvqaisyAEAT 588
                         250       260
                  ....*....|....*....|....*
gi 1034585096 506 K------ENYGLLRRKLELMQKKAV 524
Cdd:TIGR00990 589 RtqiqvqEDYPVLASKLQGMLGGLR 613
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
373-490 6.25e-07

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 227343 [Multi-domain]  Cd Length: 257  Bit Score: 50.90  E-value: 6.25e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585096 373 LGRLYADLNRHVDALNAWRNATVLKPEHSLAWNNMIILLDNTGNLAQAEAVGREALELIPNDHSLMFSLANVLGKSQKYK 452
Cdd:COG5010   106 QGKNQIRNGNFGEAVSVLRKAARLAPTDWEAWNLLGAALDQLGRFDEARRAYRQALELAPNEPSIANNLGMSLLLRGDLE 185
                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 1034585096 453 ESEALFLKAIKANPNAASYHGNLAVLYHRWGHLDLAKK 490
Cdd:COG5010   186 DAETLLLPAYLSPAADSRVRQNLALVVGLQGDFREAED 223
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
242-386 8.03e-07

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 52.01  E-value: 8.03e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585096 242 LRSGEWRSEEQLFRSALSVCPLNAKVHYNIGKNLADKGNQTAAIRYYREAVRLNPKYVHAMNNLGNILKERNElQEAEEL 321
Cdd:TIGR02917 747 LASGNTAEAVKTLEAWLKTHPNDAVLRTALAELYLAQKDYDKAIKHYQTVVKKAPDNAVVLNNLAWLYLELKD-PRALEY 825
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1034585096 322 LSLAVQIQPDFAAAWMNLGIVQNSLKRFEAAEQSYRTAIKHRRKYPDCYYNLGRLYADLNRHVDA 386
Cdd:TIGR02917 826 AERALKLAPNIPAILDTLGWLLVEKGEADRALPLLRKAVNIAPEAAAIRYHLALALLATGRKAEA 890
PRK02603 PRK02603
photosystem I assembly protein Ycf3; Provisional
267-327 1.17e-06

photosystem I assembly protein Ycf3; Provisional


Pssm-ID: 179448 [Multi-domain]  Cd Length: 172  Bit Score: 48.51  E-value: 1.17e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1034585096 267 VHYNIGKNLADKGNQTAAIRYYREAVRLNPKYVHAMNNLGNIL-------KERNELQEAEELLSLAVQ 327
Cdd:PRK02603   74 ILYNMGIIYASNGEHDKALEYYHQALELNPKQPSALNNIAVIYhkrgekaEEAGDQDEAEALFDKAAE 141
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
242-500 3.71e-06

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 49.70  E-value: 3.71e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585096 242 LRSGEWRSEEQLFRSALSVCPLNAKVHYNIGKNLADKGNQTAAIRYYREAVRLNPKYVHAMNNLGNILKERNELQEAEEL 321
Cdd:TIGR02917 374 LALGDFEKAAEYLAKATELDPENAAARTQLGISKLSQGDPSEAIADLETAAQLDPELGRADLLLILSYLRSGQFDKALAA 453
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585096 322 LSLAVQIQPDFAAAWMNLGIVQNSLKRFEAAEQSYRTAIKHRRKYPDCYYNLGRLYADLNR-----------------HV 384
Cdd:TIGR02917 454 AKKLEKKQPDNASLHNLLGAIYLGKGDLAKAREAFEKALSIEPDFFPAAANLARIDIQEGNpddaiqrfekvltidpkNL 533
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585096 385 DALNAW-----RNAtvlKPEHSLAWNNMIILLDNT---------------GNLAQAEAVGREALELIPNDHSLMFSLANV 444
Cdd:TIGR02917 534 RAILALaglylRTG---NEEEAVAWLEKAAELNPQeiepalalaqyylgkGQLKKALAILNEAADAAPDSPEAWLMLGRA 610
                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1034585096 445 LGKSQKYKESEALFLKAIKANPNAASYHGNLAVLYHRWGHLDLAKKHYEISLQLDP 500
Cdd:TIGR02917 611 QLAAGDLNKAVSSFKKLLALQPDSALALLLLADAYAVMKNYAKAITSLKRALELKP 666
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
313-521 5.38e-06

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 223533 [Multi-domain]  Cd Length: 291  Bit Score: 48.30  E-value: 5.38e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585096 313 NELQEAEELLSLAVQIQPDFAAAWMNLG-IVQNSLKRFEAAEQSYRTAIKH--RRKYPDCYYNLGRLYADLNRHVDALNA 389
Cdd:COG0457     2 KDLLLALAILLEALAKLLAEALALLEAGlALLELLGELAEALELLEEALELlpNSDLAGLLLLLALALLKLGRLEEALEL 81
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585096 390 WRNA--TVLKPEHSLAWNNMIILLDNTGNLAQAEAVGREALELIPNDHSLMFSLA-NVLGKSQKYKESEALFLKAIKANP 466
Cdd:COG0457    82 LEKAleLELLPNLAEALLNLGLLLEALGKYEEALELLEKALALDPDPDLAEALLAlGALYELGDYEEALELYEKALELDP 161
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1034585096 467 ---NAASYHGNLAVLYHRWGHLDLAKKHYEISLQLDPTASG-TKENYGLLRRKLELMQK 521
Cdd:COG0457   162 elnELAEALLALGALLEALGRYEEALELLEKALKLNPDDDAeALLNLGLLYLKLGKYEE 220
C39_PA2778_fam NF033920
PA2778 family cysteine peptidase; Members of this family are MEROPS classification C39 family ...
382-500 5.52e-06

PA2778 family cysteine peptidase; Members of this family are MEROPS classification C39 family cysteine peptidases, a group that includes many processing enzyme for peptide natural products such as lantibiotics and other bacteriocins. This family, more specifically, includes PA2778 as found in Pseudomonas aeruginosa. All members of the defining seed alignment are encoded in the vicinity of a homolog of PA2779 (see HMM NF033919). Note that the C-terminal region consists largely of tetratricopeptide repeats (TPR), so classification using this HMM must be based on comparing the top domain score to the second gathering threshold (GA2).


Pssm-ID: 411481 [Multi-domain]  Cd Length: 255  Bit Score: 47.93  E-value: 5.52e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585096 382 RHVDALNA----WRNA-----TVLKPEHS------LAWNNMIILLDNTGNLAQAEAVGREALELIPNDHSLMFSLANVLG 446
Cdd:NF033920  122 RHRLSFSTfertWARAdywalVVLPPGQLpatadpLAYLRAAQDLEQTGQPEAALAAYQTATKRWPDSWLAYFGLGNAAY 201
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1034585096 447 KSQKYKESEALFLKAIKANPNAASYHGNLAVLYHRWGHLDLAKKHYEISLQLDP 500
Cdd:NF033920  202 AAGDYAAAAAAFRQAVERHPDSAAAWNNLAYALAAQGCTAQARAAAECALALAP 255
TPR_19 pfam14559
Tetratricopeptide repeat;
279-337 6.06e-06

Tetratricopeptide repeat;


Pssm-ID: 434038 [Multi-domain]  Cd Length: 65  Bit Score: 43.73  E-value: 6.06e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1034585096 279 GNQTAAIRYYREAVRLNPKYVHAMNNLGNILKERNELQEAEELLSLAVQIQPDFAAAWM 337
Cdd:pfam14559   2 GDYAEALELLEQALAEDPDNAEARLGLAEALLALGRLDEAEALLAALPAADPDDPRYAA 60
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
215-457 1.36e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 47.77  E-value: 1.36e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585096 215 LSKHTKKKKLIAAVVLGILFintlRCVLRSGEWRSEEQLFRSALSVCPLNAKVhYNIGKNLADKGNQTAAIRYYREAVRL 294
Cdd:TIGR02917 691 IAKSLQKQHPKAALGFELEG----DLYLRQKDYPAAIQAYRKALKRAPSSQNA-IKLHRALLASGNTAEAVKTLEAWLKT 765
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585096 295 NPKYVHAMNNLGNILKERNELQEAEELLSLAVQIQPDFAAAWMNLGIVQNSLKRFEAAEQSYRtAIKHRRKYPDCYYNLG 374
Cdd:TIGR02917 766 HPNDAVLRTALAELYLAQKDYDKAIKHYQTVVKKAPDNAVVLNNLAWLYLELKDPRALEYAER-ALKLAPNIPAILDTLG 844
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585096 375 RLYADlnrhvdalnawrnatvlkpehslawnnmiilldnTGNLAQAEAVGREALELIPNDHSLMFSLANVLGKSQKYKES 454
Cdd:TIGR02917 845 WLLVE----------------------------------KGEADRALPLLRKAVNIAPEAAAIRYHLALALLATGRKAEA 890

                  ...
gi 1034585096 455 EAL 457
Cdd:TIGR02917 891 RKE 893
TPR_16 pfam13432
Tetratricopeptide repeat; This family is found predominantly at the C-terminus of ...
269-331 2.30e-05

Tetratricopeptide repeat; This family is found predominantly at the C-terminus of transglutaminase enzyme core regions.


Pssm-ID: 433202 [Multi-domain]  Cd Length: 68  Bit Score: 42.32  E-value: 2.30e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1034585096 269 YNIGKNLADKGNQTAAIRYYREAVRLN---PKYVHAMNNLGNILKERNELQEAEELLSLAVQIQPD 331
Cdd:pfam13432   1 LALARAALRAGDYDDAAAALEAALARFpesPDAAAALLLLGLAALRQGRLAEAAAAYRAALRAAPG 66
TPR_12 pfam13424
Tetratricopeptide repeat;
301-365 3.55e-05

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 41.99  E-value: 3.55e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1034585096 301 AMNNLGNILKERNELQEAEELLSLAVQIQ--------PDFAAAWMNLGIVQNSLKRFEAAEQSYRTAIKHRRK 365
Cdd:pfam13424   5 ALNNLAAVLRRLGRYDEALELLEKALEIArrllgpdhPLTATTLLNLGRLYLELGRYEEALELLERALALAEK 77
ycf3 CHL00033
photosystem I assembly protein Ycf3
269-325 7.20e-05

photosystem I assembly protein Ycf3


Pssm-ID: 176974 [Multi-domain]  Cd Length: 168  Bit Score: 43.46  E-value: 7.20e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1034585096 269 YNIGKNLADKGNQTAAIRYYREAVRLNPKYVHAMNNL-------GNILKERNELQEAEELLSLA 325
Cdd:CHL00033   76 YNIGLIHTSNGEHTKALEYYFQALERNPFLPQALNNMavichyrGEQAIEQGDSEIAEAWFDQA 139
PilF COG3063
Tfp pilus assembly protein PilF [Cell motility, Extracellular structures];
449-510 9.22e-05

Tfp pilus assembly protein PilF [Cell motility, Extracellular structures];


Pssm-ID: 225605 [Multi-domain]  Cd Length: 250  Bit Score: 43.95  E-value: 9.22e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1034585096 449 QKYKESEALFLKAIKANPNAASYHGNLAVLYHRWGHLDLAKKHYEISLQLDPTASGTKENYG 510
Cdd:COG3063    49 GDYAQAKKNLEKALEHDPSYYLAHLVRAHYYQKLGENDLADESYRKALSLAPNNGDVLNNYG 110
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
242-355 1.57e-04

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 227343 [Multi-domain]  Cd Length: 257  Bit Score: 43.58  E-value: 1.57e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585096 242 LRSGEWRSEEQLFRSALSVCPLNAKVHYNIGKNLADKGNQTAAIRYYREAVRLNPKYVHAMNNLGNILKERNELQEAEEL 321
Cdd:COG5010   111 IRNGNFGEAVSVLRKAARLAPTDWEAWNLLGAALDQLGRFDEARRAYRQALELAPNEPSIANNLGMSLLLRGDLEDAETL 190
                          90       100       110
                  ....*....|....*....|....*....|....
gi 1034585096 322 LSLAVQIQPDFAAAWMNLGIVQNSLKRFEAAEQS 355
Cdd:COG5010   191 LLPAYLSPAADSRVRQNLALVVGLQGDFREAEDI 224
TPR_12 pfam13424
Tetratricopeptide repeat;
331-389 1.61e-04

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 40.06  E-value: 1.61e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1034585096 331 DFAAAWMNLGIVQNSLKRFEAAEQSYRTAIKHRRKYPD--------CYYNLGRLYADLNRHVDALNA 389
Cdd:pfam13424   1 DVATALNNLAAVLRRLGRYDEALELLEKALEIARRLLGpdhpltatTLLNLGRLYLELGRYEEALEL 67
TPR_12 pfam13424
Tetratricopeptide repeat;
265-331 2.35e-04

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 39.68  E-value: 2.35e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1034585096 265 AKVHYNIGKNLADKGNQTAAIRYYREAVRL--------NPKYVHAMNNLGNILKERNELQEAEELLSLAVQIQPD 331
Cdd:pfam13424   3 ATALNNLAAVLRRLGRYDEALELLEKALEIarrllgpdHPLTATTLLNLGRLYLELGRYEEALELLERALALAEK 77
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
230-352 4.78e-04

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 223533 [Multi-domain]  Cd Length: 291  Bit Score: 42.14  E-value: 4.78e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585096 230 LGILFINTLRCVLRSGEWRSEEQLFRSALSVCP-LNAKVHYNIGKNLADKGNQTAAIRYYREAVRLNPKYVHAMNNLGNI 308
Cdd:COG0457   166 LAEALLALGALLEALGRYEEALELLEKALKLNPdDDAEALLNLGLLYLKLGKYEEALEYYEKALELDPDNAEALYNLALL 245
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 1034585096 309 LKERNELQEAEELLSLAVQIQPD-FAAAWMNLGIVQNSLKRFEAA 352
Cdd:COG0457   246 LLELGRYEEALEALEKALELDPDlYNLGLALLLLLAEALELLEKA 290
TPR_1 pfam00515
Tetratricopeptide repeat;
333-366 5.44e-04

Tetratricopeptide repeat;


Pssm-ID: 425728 [Multi-domain]  Cd Length: 34  Bit Score: 37.40  E-value: 5.44e-04
                          10        20        30
                  ....*....|....*....|....*....|....
gi 1034585096 333 AAAWMNLGIVQNSLKRFEAAEQSYRTAIKHRRKY 366
Cdd:pfam00515   1 AKALYNLGNAYFKLGKYDEALEYYEKALELNPNN 34
TPR_1 pfam00515
Tetratricopeptide repeat;
265-298 6.06e-04

Tetratricopeptide repeat;


Pssm-ID: 425728 [Multi-domain]  Cd Length: 34  Bit Score: 37.40  E-value: 6.06e-04
                          10        20        30
                  ....*....|....*....|....*....|....
gi 1034585096 265 AKVHYNIGKNLADKGNQTAAIRYYREAVRLNPKY 298
Cdd:pfam00515   1 AKALYNLGNAYFKLGKYDEALEYYEKALELNPNN 34
TPR_17 pfam13431
Tetratricopeptide repeat;
287-320 7.05e-04

Tetratricopeptide repeat;


Pssm-ID: 433201 [Multi-domain]  Cd Length: 34  Bit Score: 37.14  E-value: 7.05e-04
                          10        20        30
                  ....*....|....*....|....*....|....
gi 1034585096 287 YYREAVRLNPKYVHAMNNLGNILKERNELQEAEE 320
Cdd:pfam13431   1 LYLKALELDPNNADAYYNLAVLLLELGQSETALQ 34
TPR_19 pfam14559
Tetratricopeptide repeat;
415-478 7.10e-04

Tetratricopeptide repeat;


Pssm-ID: 434038 [Multi-domain]  Cd Length: 65  Bit Score: 37.95  E-value: 7.10e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1034585096 415 GNLAQAEAVGREALELIPNDHSLMFSLANVLGKSQKYKESEALFLKAIKANPNAASYHGNLAVL 478
Cdd:pfam14559   2 GDYAEALELLEQALAEDPDNAEARLGLAEALLALGRLDEAEALLAALPAADPDDPRYAALLAKL 65
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
367-503 7.32e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 42.38  E-value: 7.32e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585096 367 PDCYYNLGRLYADLNRHVDALNAWRNATVLKPEHSLAWNNMIILLDNTGNLAQAEAVGREALELIPNDHSLMFSLANVLG 446
Cdd:TIGR02917  22 PEELIEAAKSYLQKNKYKAAIIQLKNALQKDPNDAEARFLLGKIYLALGDYAAAEKELRKALSLGYPKNQVLPLLARAYL 101
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1034585096 447 KSQKYKESEALFLKA-IKANPNAASYHGNLAVLYHRWGHLDLAKKHYEISLQLDPTAS 503
Cdd:TIGR02917 102 LQGKFQQVLDELPGKtLLDDEGAAELLALRGLAYLGLGQLELAQKSYEQALAIDPRSL 159
TPR_2 pfam07719
Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats ...
265-297 7.74e-04

Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats (TPR) that are not matched by pfam00515.


Pssm-ID: 429619 [Multi-domain]  Cd Length: 33  Bit Score: 37.12  E-value: 7.74e-04
                          10        20        30
                  ....*....|....*....|....*....|...
gi 1034585096 265 AKVHYNIGKNLADKGNQTAAIRYYREAVRLNPK 297
Cdd:pfam07719   1 AEALYNLGLAYYKLGDYEEALEAYEKALELDPN 33
TPR_12 pfam13424
Tetratricopeptide repeat;
441-498 8.10e-04

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 38.14  E-value: 8.10e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1034585096 441 LANVLGKSQKYKESEALFLKAIKA--------NPNAASYHGNLAVLYHRWGHLDLAKKHYEISLQL 498
Cdd:pfam13424   9 LAAVLRRLGRYDEALELLEKALEIarrllgpdHPLTATTLLNLGRLYLELGRYEEALELLERALAL 74
TPR_16 pfam13432
Tetratricopeptide repeat; This family is found predominantly at the C-terminus of ...
371-434 1.06e-03

Tetratricopeptide repeat; This family is found predominantly at the C-terminus of transglutaminase enzyme core regions.


Pssm-ID: 433202 [Multi-domain]  Cd Length: 68  Bit Score: 37.70  E-value: 1.06e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1034585096 371 YNLGRLYADLNRHVDALNAWRNAT---VLKPEHSLAWNNMIILLDNTGNLAQAEAVGREALELIPND 434
Cdd:pfam13432   1 LALARAALRAGDYDDAAAALEAALarfPESPDAAAALLLLGLAALRQGRLAEAAAAYRAALRAAPGD 67
PilF COG3063
Tfp pilus assembly protein PilF [Cell motility, Extracellular structures];
333-467 1.11e-03

Tfp pilus assembly protein PilF [Cell motility, Extracellular structures];


Pssm-ID: 225605 [Multi-domain]  Cd Length: 250  Bit Score: 40.87  E-value: 1.11e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585096 333 AAAWMNLGIVQNSLKRFEAAEQSYRTAIKHRRKYPDCYYNLGRLYADLNRHVDALNAWRNATVLKPEHSLAWNNMIILLD 412
Cdd:COG3063    35 AKARLQLALGYLQQGDYAQAKKNLEKALEHDPSYYLAHLVRAHYYQKLGENDLADESYRKALSLAPNNGDVLNNYGAFLC 114
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1034585096 413 NTGNLAQAEAVGREALELiPNDHSLMFSLANVLG---KSQKYKESEALFLKAIKANPN 467
Cdd:COG3063   115 AQGRPEEAMQQFERALAD-PAYGEPSDTLENLGLcalKAGQFDQAEEYLKRALELDPQ 171
TPR_11 pfam13414
TPR repeat;
272-311 1.28e-03

TPR repeat;


Pssm-ID: 315977 [Multi-domain]  Cd Length: 42  Bit Score: 36.68  E-value: 1.28e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 1034585096 272 GKNLADKGNQTAAIRYYREAVRLNPKYVHAMNNLGNILKE 311
Cdd:pfam13414   1 GDAYYEQGKYEEAIEAYKKALKLDPDNPEAYYNLGLAYYK 40
YfgC COG4783
Putative Zn-dependent protease, contains TPR repeats [General function prediction only];
286-434 1.49e-03

Putative Zn-dependent protease, contains TPR repeats [General function prediction only];


Pssm-ID: 227122 [Multi-domain]  Cd Length: 484  Bit Score: 41.23  E-value: 1.49e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585096 286 RYYREAVRLNPKYVHAMnnlgnILKERNELQEAEELLSLAVQIQPDFAAAWMNLGIVQNSLKRFEAAEQSYRTAIKHRRK 365
Cdd:COG4783   264 PPYNKLDSPDFQLARAR-----IRAKYEALPNQQAADLLAKRSKRGGLAAQYGRALQTYLAGQYDEALKLLQPLIAAQPD 338
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1034585096 366 YPdcYYN--LGRLYADLNRHVDALNAWRNATVLKPEHSLAWNNMIILLDNTGNLAQAEAVGREALELIPND 434
Cdd:COG4783   339 NP--YYLelAGDILLEANKAKEAIERLKKALALDPNSPLLQLNLAQALLKGGKPQEAIRILNRYLFNDPED 407
TPR_8 pfam13181
Tetratricopeptide repeat;
265-297 1.52e-03

Tetratricopeptide repeat;


Pssm-ID: 404131 [Multi-domain]  Cd Length: 33  Bit Score: 36.22  E-value: 1.52e-03
                          10        20        30
                  ....*....|....*....|....*....|...
gi 1034585096 265 AKVHYNIGKNLADKGNQTAAIRYYREAVRLNPK 297
Cdd:pfam13181   1 AEAYYNLGLIYLKLGDYEEAKEYYEKALELDPD 33
type_IV_pilW TIGR02521
type IV pilus biogenesis/stability protein PilW; Members of this family are designated PilF ...
415-516 1.96e-03

type IV pilus biogenesis/stability protein PilW; Members of this family are designated PilF and PilW. This outer membrane protein is required both for pilus stability and for pilus function such as adherence to human cells. Members of this family contain copies of the TPR (tetratricopeptide repeat) domain.


Pssm-ID: 131573 [Multi-domain]  Cd Length: 234  Bit Score: 40.01  E-value: 1.96e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585096 415 GNLAQAEAVGREALELIPNDHSLMFSLANVLGKSQKYKESEALFLKAIKANPNAASYHGNL-AVLYHRwGHLDLAKKHYE 493
Cdd:TIGR02521  45 GDLEVAKENLDKALEHDPDDYLAYLALALYYQQLGELEKAEDSFRRALTLNPNNGDVLNNYgTFLCQQ-GKYEQAMQQFE 123
                          90       100
                  ....*....|....*....|....*
gi 1034585096 494 --ISLQLDPTASGTKENYGLLRRKL 516
Cdd:TIGR02521 124 qaIEDPLYPQPARSLENAGLCALKA 148
TPR_16 pfam13432
Tetratricopeptide repeat; This family is found predominantly at the C-terminus of ...
304-367 2.05e-03

Tetratricopeptide repeat; This family is found predominantly at the C-terminus of transglutaminase enzyme core regions.


Pssm-ID: 433202 [Multi-domain]  Cd Length: 68  Bit Score: 36.93  E-value: 2.05e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1034585096 304 NLGNILKERNELQEAEELLSLAVQIQ---PDFAAAWMNLGIVQNSLKRFEAAEQSYRTAIKHRRKYP 367
Cdd:pfam13432   2 ALARAALRAGDYDDAAAALEAALARFpesPDAAAALLLLGLAALRQGRLAEAAAAYRAALRAAPGDP 68
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
346-523 2.65e-03

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 223533 [Multi-domain]  Cd Length: 291  Bit Score: 39.83  E-value: 2.65e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585096 346 LKRFEAAEQSYRTAIKHRRKYPDCYYNLGR-LYADLNRHVDALNAWRNATVLKPEHSLA--WNNMIILLDNTGNLAQAEA 422
Cdd:COG0457     1 LKDLLLALAILLEALAKLLAEALALLEAGLaLLELLGELAEALELLEEALELLPNSDLAglLLLLALALLKLGRLEEALE 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585096 423 VGREALE--LIPNDHSLMFSLANVLGKSQKYKESEALFLKAIKANPNAASYHGNLA-VLYHRWGHLDLAKKHYEISLQLD 499
Cdd:COG0457    81 LLEKALEleLLPNLAEALLNLGLLLEALGKYEEALELLEKALALDPDPDLAEALLAlGALYELGDYEEALELYEKALELD 160
                         170       180
                  ....*....|....*....|....
gi 1034585096 500 PTASGTKENYGLLRRKLELMQKKA 523
Cdd:COG0457   161 PELNELAEALLALGALLEALGRYE 184
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
333-366 2.85e-03

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 35.50  E-value: 2.85e-03
                           10        20        30
                   ....*....|....*....|....*....|....
gi 1034585096  333 AAAWMNLGIVQNSLKRFEAAEQSYRTAIKHRRKY 366
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
TPR_11 pfam13414
TPR repeat;
306-343 3.07e-03

TPR repeat;


Pssm-ID: 315977 [Multi-domain]  Cd Length: 42  Bit Score: 35.53  E-value: 3.07e-03
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 1034585096 306 GNILKERNELQEAEELLSLAVQIQPDFAAAWMNLGIVQ 343
Cdd:pfam13414   1 GDAYYEQGKYEEAIEAYKKALKLDPDNPEAYYNLGLAY 38
TPR_17 pfam13431
Tetratricopeptide repeat;
457-490 3.47e-03

Tetratricopeptide repeat;


Pssm-ID: 433201 [Multi-domain]  Cd Length: 34  Bit Score: 35.21  E-value: 3.47e-03
                          10        20        30
                  ....*....|....*....|....*....|....
gi 1034585096 457 LFLKAIKANPNAASYHGNLAVLYHRWGHLDLAKK 490
Cdd:pfam13431   1 LYLKALELDPNNADAYYNLAVLLLELGQSETALQ 34
TPR_11 pfam13414
TPR repeat;
345-380 3.52e-03

TPR repeat;


Pssm-ID: 315977 [Multi-domain]  Cd Length: 42  Bit Score: 35.14  E-value: 3.52e-03
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 1034585096 345 SLKRFEAAEQSYRTAIKHRRKYPDCYYNLGRLYADL 380
Cdd:pfam13414   6 EQGKYEEAIEAYKKALKLDPDNPEAYYNLGLAYYKL 41
TPR COG0790
TPR repeat [Signal transduction mechanisms];
278-378 4.02e-03

TPR repeat [Signal transduction mechanisms];


Pssm-ID: 223861 [Multi-domain]  Cd Length: 292  Bit Score: 39.26  E-value: 4.02e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585096 278 KGNQTAAIRYYREAVRLNpkYVHAMNNLGNILKE----RNELQEAEELLSLAV-QIQPDFAAAWMNLGIVQNS------- 345
Cdd:COG0790    90 SRDKTKAADWYRCAAADG--LAEALFNLGLMYANgrgvPLDLVKALKYYEKAAkLGNVEAALAMYRLGLAYLSglqalav 167
                          90       100       110
                  ....*....|....*....|....*....|...
gi 1034585096 346 LKRFEAAEQSYRTAikHRRKYPDCYYNLGRLYA 378
Cdd:COG0790   168 AYDDKKALYLYRKA--AELGNPDAQLLLGRMYE 198
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
265-298 4.18e-03

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 34.73  E-value: 4.18e-03
                           10        20        30
                   ....*....|....*....|....*....|....
gi 1034585096  265 AKVHYNIGKNLADKGNQTAAIRYYREAVRLNPKY 298
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
TPR_10 pfam13374
Tetratricopeptide repeat;
301-329 4.20e-03

Tetratricopeptide repeat;


Pssm-ID: 433156 [Multi-domain]  Cd Length: 42  Bit Score: 35.17  E-value: 4.20e-03
                          10        20
                  ....*....|....*....|....*....
gi 1034585096 301 AMNNLGNILKERNELQEAEELLSLAVQIQ 329
Cdd:pfam13374   4 SLNNLANALRAQGRYDEAEELLEEALAIR 32
TPR_19 pfam14559
Tetratricopeptide repeat;
313-376 4.79e-03

Tetratricopeptide repeat;


Pssm-ID: 434038 [Multi-domain]  Cd Length: 65  Bit Score: 35.64  E-value: 4.79e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1034585096 313 NELQEAEELLSLAVQIQPDFAAAWMNLGIVQNSLKRFEAAEQSYRTAIKHRRKYPDCYYNLGRL 376
Cdd:pfam14559   2 GDYAEALELLEQALAEDPDNAEARLGLAEALLALGRLDEAEALLAALPAADPDDPRYAALLAKL 65
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
373-469 4.99e-03

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 226687 [Multi-domain]  Cd Length: 287  Bit Score: 38.90  E-value: 4.99e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1034585096 373 LGRLYADLNRHVDALNAWRNATVL---KPEHSLAWNNMIILLDNTGNLAQAEAVGREALELIPNDHSLMFSLANVLGKSQ 449
Cdd:COG4235   162 LGRAYMALGRASDALLAYRNALRLagdNPEILLGLAEALYYQAGQQMTAKARALLRQALALDPANIRALSLLAFAAFEQG 241
                          90       100
                  ....*....|....*....|
gi 1034585096 450 KYKESEALFLKAIKANPNAA 469
Cdd:COG4235   242 DYAEAAAAWQMLLDLLPADD 261
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
367-400 7.47e-03

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 34.34  E-value: 7.47e-03
                           10        20        30
                   ....*....|....*....|....*....|....
gi 1034585096  367 PDCYYNLGRLYADLNRHVDALNAWRNATVLKPEH 400
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.20
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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