|
Name |
Accession |
Description |
Interval |
E-value |
| PACT_coil_coil |
pfam10495 |
Pericentrin-AKAP-450 domain of centrosomal targeting protein; This domain is a coiled-coil ... |
1891-1969 |
4.87e-27 |
|
Pericentrin-AKAP-450 domain of centrosomal targeting protein; This domain is a coiled-coil region close to the C-terminus of centrosomal proteins that is directly responsible for recruiting AKAP-450 and pericentrin to the centrosome. Hence the suggested name for this region is a PACT domain (pericentrin-AKAP-450 centrosomal targeting). This domain is also present at the C-terminus of coiled-coil proteins from Drosophila and S. pombe, and that from the Drosophila protein is sufficient for targeting to the centrosome in mammalian cells. The function of these proteins is unknown but they seem good candidates for having a centrosomal or spindle pole body location. The final 22 residues of this domain in AKAP-450 appear specifically to be a calmodulin-binding domain indicating that this member at least is likely to contribute to centrosome assembly.
Pssm-ID: 463115 Cd Length: 77 Bit Score: 105.75 E-value: 4.87e-27
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1039732412 1891 YLRAESFRKALIYQKKYLLLLIGGFQDSEQETLSMIAHLGVFPSKADKKitmSRPFTKFRTAVRVVIAVLRLRFLVKKW 1969
Cdd:pfam10495 2 LLREESFRKDLAYQKKYLLLLLGGYQACNKADLRLLAQMGVTPPDDRPS---RKPRRKLKSAALAVIAIARMKRLAREW 77
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
170-756 |
8.24e-14 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 77.28 E-value: 8.24e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 170 QQELLERLREESAAKDRLA-LELHTAKGLLEGFKVEKVDLQEALGKKEESEQQLILELEDLRKQLQQAARELLTLKEEKS 248
Cdd:COG1196 219 KEELKELEAELLLLKLRELeAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELA 298
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 249 VLWNQKETLTNEAKEREAgspvlpahKDTALQEEVESLTrvqwESRKQSEKDRATLLSQMRVLESELEDQLvqhrgcAQL 328
Cdd:COG1196 299 RLEQDIARLEERRRELEE--------RLEELEEELAELE----EELEELEEELEELEEELEEAEEELEEAE------AEL 360
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 329 AEEVATLKQQLAALDKHLRSQRQFmDDQAAEREHEREEFQQEIQRLEGQLRQAARprppgprdsQCVQLDEEVELLQEKL 408
Cdd:COG1196 361 AEAEEALLEAEAELAEAEEELEEL-AEELLEALRAAAELAAQLEELEEAEEALLE---------RLERLEEELEELEEAL 430
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 409 REKLDGFNELVIKKDFADQQLLIQEEEIKRLEETNASIQRQMVQLQEELEKQKKSMEELKEKEILKQENMGD--LLLTTV 486
Cdd:COG1196 431 AELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADyeGFLEGV 510
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 487 SRSGLDEAGCPMLPQGSSSRGPEAQPDVTERALLqhENEVVHRRNSEIDELKSLIENLQEN-------------QRQLQK 553
Cdd:COG1196 511 KAALLLAGLRGLAGAVAVLIGVEAAYEAALEAAL--AAALQNIVVEDDEVAAAAIEYLKAAkagratflpldkiRARAAL 588
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 554 DKAEEIEQLHEVIEKLQSELSLMGPKVHEVSDPQAGSLHSELACLRGEGLGGQALRSELQAAQAAKEVF--GQLLADQAH 631
Cdd:COG1196 589 AAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSagGSLTGGSRR 668
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 632 GHSQALEALQQRLQDAEEVAARHLAELEHcVALREAEVEAMASQIQEFAATLKAKEAIIEQRDLEIDAvnkwkvshslel 711
Cdd:COG1196 669 ELLAALLEAEAELEELAERLAEEELELEE-ALLAEEEEERELAEAEEERLEEELEEEALEEQLEAERE------------ 735
|
570 580 590 600
....*....|....*....|....*....|....*....|....*
gi 1039732412 712 eAILLALAHFRHALEQQTCATPDEPPELRQLRVQCARLSHQLQVL 756
Cdd:COG1196 736 -ELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEAL 779
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
121-704 |
2.52e-12 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 72.66 E-value: 2.52e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 121 YQSLSTAVEGLLEMALDSSKQLEEARQLHRCVEREFRHRNEEMAQAMQKQQELLERLREESAAKDRLALELHTAKGLLEG 200
Cdd:COG1196 234 LRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRE 313
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 201 FKVEKVDLQEALGKKEESEQQLILELEDLRKQLQQAARELLTLKEEksvLWNQKETLTNEAKEREagspvlpahkdtALQ 280
Cdd:COG1196 314 LEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAE---LAEAEEALLEAEAELA------------EAE 378
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 281 EEVESLTRVQWESRKQSEKDRATLLSQMRVLESELEDQLVQHRGCAQLAEEVATLKQQLAALDKHLRSQRQFMDDQAAER 360
Cdd:COG1196 379 EELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEE 458
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 361 EHEREEFQQEIQRLEGQLRQAARPRPPgprdsqcVQLDEEVELLQEKLREKLDGFNELVIKKDFADQQ--------LLIQ 432
Cdd:COG1196 459 EALLELLAELLEEAALLEAALAELLEE-------LAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLrglagavaVLIG 531
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 433 EEEIKRLEETNASIQRQMVQLQEELEKQKKSMEELKEKeilkqenmgdlLLTTVSRSGLDEAgcpmlpQGSSSRGPEAQP 512
Cdd:COG1196 532 VEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAA-----------KAGRATFLPLDKI------RARAALAAALAR 594
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 513 DVTERALLQHENEVVHRRNSEIDELKSLIENLQENQRQLQKDKAEEIEQLHEVIEKLQSELSLMGPkvhevsdpqagslh 592
Cdd:COG1196 595 GAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGG-------------- 660
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 593 selaclRGEGLGGQALRSELQAAQAAKEVFGQLLADQAHGHSQALEALQQRLQDAEEVAARHLAELEHCVALREAEVEAM 672
Cdd:COG1196 661 ------SLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAER 734
|
570 580 590
....*....|....*....|....*....|..
gi 1039732412 673 ASQIQEFAATLKAKEAIIEQRDLEIDAVNKWK 704
Cdd:COG1196 735 EELLEELLEEEELLEEEALEELPEPPDLEELE 766
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
122-645 |
3.22e-12 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 72.28 E-value: 3.22e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 122 QSLSTAVEGLLEMALDSSKQLEEARQLHRCVEREFRHRNEEMAQAMQKQQEL-------LERLREESAAKDRLALELHTA 194
Cdd:COG1196 249 EELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLeqdiarlEERRRELEERLEELEEELAEL 328
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 195 KGLLEGFKVEKVDLQEALGKKEESEQQLILELEDLRKQLQQAARELLTLKEEKSVLWNQKETLTNEAKEREAgspvlpah 274
Cdd:COG1196 329 EEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAA-------- 400
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 275 KDTALQEEVESLTRVQWESRKQSEKDRATLLSQMRVLESELEDQLVQHRGCAQLAEEVATLKQQLAALDKHLRSQRQFMD 354
Cdd:COG1196 401 QLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALA 480
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 355 DQAAEREHEREEF---QQEIQRLEGQLRQAARPR--PPGPRDSQCVQLDEEVELLQEK-LREKLDGFNELVIKKDFADQQ 428
Cdd:COG1196 481 ELLEELAEAAARLlllLEAEADYEGFLEGVKAALllAGLRGLAGAVAVLIGVEAAYEAaLEAALAAALQNIVVEDDEVAA 560
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 429 LLIQE--------------EEIKRLEETNASIQRQMVQ---------LQEELEKQKKSMEELKEKEILKQENMGDLLLTT 485
Cdd:COG1196 561 AAIEYlkaakagratflplDKIRARAALAAALARGAIGaavdlvasdLREADARYYVLGDTLLGRTLVAARLEAALRRAV 640
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 486 VSRSGLDEAGCPM---LPQGSSSRGPEAQPDVTERALLQHENEVVHRRNSEIDELKSLIENLQENQRQLQKDKAEEIEQL 562
Cdd:COG1196 641 TLAGRLREVTLEGeggSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEE 720
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 563 HEVIEKLQSELSLMGPKVHEVSDPQAGSLHSELAcLRGEGLGGQALRSELQAAQAAKEVFGQ--LLADQAHghsqalEAL 640
Cdd:COG1196 721 LEEEALEEQLEAEREELLEELLEEEELLEEEALE-ELPEPPDLEELERELERLEREIEALGPvnLLAIEEY------EEL 793
|
....*
gi 1039732412 641 QQRLQ 645
Cdd:COG1196 794 EERYD 798
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
140-791 |
4.18e-11 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 68.54 E-value: 4.18e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 140 KQLEEARQLHRCVEREFRHRNEEMAQAMQKQQELLERLREESAAKDRLALELHTAKGLLEGFKVEKVDLQEALGKKEESE 219
Cdd:TIGR02168 288 KELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAEL 367
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 220 QQLILELEDLRKQLQQAARELLTLKEEKSVLWNQ-----------KETLTNEAKEREAGSPVLPAHKDTALQEEVESLTR 288
Cdd:TIGR02168 368 EELESRLEELEEQLETLRSKVAQLELQIASLNNEierlearlerlEDRRERLQQEIEELLKKLEEAELKELQAELEELEE 447
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 289 VQWESRKQSEKDRATLLSQMRVLESELEDQLVQHRGCAQLAEEVATLKQQLAALDKHLRSQRQFMDDQAAEREHEREEfq 368
Cdd:TIGR02168 448 ELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVL-- 525
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 369 QEIQRLEGQLRQAARPRPPGPRDSQCVQLDEEVELLQEKLREKLDGFNELVIKKDFADQQLLIQEEEIKRLEETNASIQR 448
Cdd:TIGR02168 526 SELISVDEGYEAAIEAALGGRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAK 605
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 449 QMVQLQEELEKQKKSM-------EELKEK-EILKQENMGDLLLT----TVSRSG-------------------LDEAGCP 497
Cdd:TIGR02168 606 DLVKFDPKLRKALSYLlggvlvvDDLDNAlELAKKLRPGYRIVTldgdLVRPGGvitggsaktnssilerrreIEELEEK 685
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 498 MLPQGSSSRGPEAQPDVTERALLQHENEV-------------VHRRNSEIDELKSLIENLQENQRQLQK---DKAEEIEQ 561
Cdd:TIGR02168 686 IEELEEKIAELEKALAELRKELEELEEELeqlrkeleelsrqISALRKDLARLEAEVEQLEERIAQLSKeltELEAEIEE 765
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 562 LHEVIEKLQSELSLMGPKVHEVSDPQAG-------------SLHSELACLRGEGLGGQALRSELQAAQAAKEVFGQLLAD 628
Cdd:TIGR02168 766 LEERLEEAEEELAEAEAEIEELEAQIEQlkeelkalrealdELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEE 845
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 629 QAHGHSQALEALQQRLQDAEEVAARHLAELEHCVALREAEVEAMA---SQIQEFAATLKAKEAIIEQRDLEIDAVNKWKV 705
Cdd:TIGR02168 846 QIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALAllrSELEELSEELRELESKRSELRRELEELREKLA 925
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 706 SHSLELEAILLALAHFRHALEQQTCATPDEPPELRQLRVQCARlshqlqvlyrpflKCRMQLDQHQPHVASIGCANPCAD 785
Cdd:TIGR02168 926 QLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEE-------------EARRRLKRLENKIKELGPVNLAAI 992
|
....*.
gi 1039732412 786 DELEQE 791
Cdd:TIGR02168 993 EEYEEL 998
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
121-693 |
4.29e-11 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 68.54 E-value: 4.29e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 121 YQSLSTAVEGL-LEMALDSSKQLEEARQLHRCVEREFRHRNEEMAQAMQKQQELLERLREESAAKDRlalELHTAKGLLE 199
Cdd:TIGR02168 215 YKELKAELRELeLALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEE---EIEELQKELY 291
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 200 GFKVEKVDLQEALGKKEESEQQLI-------LELEDLRKQLQQAARELLTLKEEKSVLWNQKETLTNEAKEREAGSPVLP 272
Cdd:TIGR02168 292 ALANEISRLEQQKQILRERLANLErqleeleAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELE 371
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 273 AHKDtALQEEVESLTRvqweSRKQSEKDRATLLSQMRVLESELEdQLVQHRgcAQLAEEVATLKQQLAALDKH-LRSQRQ 351
Cdd:TIGR02168 372 SRLE-ELEEQLETLRS----KVAQLELQIASLNNEIERLEARLE-RLEDRR--ERLQQEIEELLKKLEEAELKeLQAELE 443
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 352 FMDDQAAEREHEREEFQQEIQRLEGQLRQAARPRPPGPRDSQcvQLDEEVELLqEKLREKLDGFNELVI-----KKDFAD 426
Cdd:TIGR02168 444 ELEEELEELQEELERLEEALEELREELEEAEQALDAAERELA--QLQARLDSL-ERLQENLEGFSEGVKallknQSGLSG 520
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 427 -----QQLLIQEEEIKRLEETNASIQRQMVqLQEELEKQKKSMEELKEKEILKqenMGDLLLTTVSRSGLDEAGCPMLPQ 501
Cdd:TIGR02168 521 ilgvlSELISVDEGYEAAIEAALGGRLQAV-VVENLNAAKKAIAFLKQNELGR---VTFLPLDSIKGTEIQGNDREILKN 596
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 502 GSSSRG---------PEAQPDVTerALLQH--------------------------ENEVVHR----------------- 529
Cdd:TIGR02168 597 IEGFLGvakdlvkfdPKLRKALS--YLLGGvlvvddldnalelakklrpgyrivtlDGDLVRPggvitggsaktnssile 674
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 530 RNSEIDELKSLIENLQENQRQLQK---DKAEEIEQLHEVIEKLQSELSLMGPKVHEvsdpqagsLHSELACLRGEGLGGQ 606
Cdd:TIGR02168 675 RRREIEELEEKIEELEEKIAELEKalaELRKELEELEEELEQLRKELEELSRQISA--------LRKDLARLEAEVEQLE 746
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 607 ALRSELQAAQAAKEVFGQLLADQAHGHSQALEALQQRLQDAEEVAARHLAELEhcvALREA--EVEAMASQIQEFAATLK 684
Cdd:TIGR02168 747 ERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELK---ALREAldELRAELTLLNEEAANLR 823
|
....*....
gi 1039732412 685 AKEAIIEQR 693
Cdd:TIGR02168 824 ERLESLERR 832
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
152-469 |
6.65e-10 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 64.70 E-value: 6.65e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 152 VEREFRHRNEEMAQAMQKQQELLERLREESAAKDRLALELHTAKGLLEGFKVEKVDLQEALGKKEESEQQlilELEDLRK 231
Cdd:TIGR02169 668 FSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKE---RLEELEE 744
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 232 QLQQAARELLTLKEEKSVLWNQKETLTNE-AKEREAgspvLPAHKDTALQEEVESLTRvqwESRKQsEKDRATLLSQMRV 310
Cdd:TIGR02169 745 DLSSLEQEIENVKSELKELEARIEELEEDlHKLEEA----LNDLEARLSHSRIPEIQA---ELSKL-EEEVSRIEARLRE 816
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 311 LESELEDQlvqHRGCAQLAEEVATLKQQLAALDkhlrSQRQFMDDQAAEREHEREEFQQEIQRLEGQLRQAarprppgpr 390
Cdd:TIGR02169 817 IEQKLNRL---TLEKEYLEKEIQELQEQRIDLK----EQIKSIEKEIENLNGKKEELEEELEELEAALRDL--------- 880
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 391 DSQCVQLDEEVELLQEKLREKLDGFNELVIKKDFADQQLLIQEEEIKRLEETNASIQRQMVQLQEE------LEKQKKSM 464
Cdd:TIGR02169 881 ESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIpeeelsLEDVQAEL 960
|
....*
gi 1039732412 465 EELKE 469
Cdd:TIGR02169 961 QRVEE 965
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
133-569 |
7.55e-10 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 64.57 E-value: 7.55e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 133 EMALDSSKQLEEARQLHRCVEREFRHRNE------EMAQAMQKQQELLERLREESAAKDRLALELHTAKGLLEGFKVEKV 206
Cdd:COG1196 366 ALLEAEAELAEAEEELEELAEELLEALRAaaelaaQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALE 445
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 207 DLQEALGKKEESEQQLILELEDLRKQLQQAARELLTLKEEKSVLWNQKETLTNEAKEREA-GSPVLPAHKDTALQEEVES 285
Cdd:COG1196 446 EAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGfLEGVKAALLLAGLRGLAGA 525
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 286 LTRVQWESRKQSEKDRATLLSQMRVLESELEDQLVQHR--------GCAQLAEEVATLKQQLAALDKHLRSQRQFMDDQA 357
Cdd:COG1196 526 VAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIeylkaakaGRATFLPLDKIRARAALAAALARGAIGAAVDLVA 605
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 358 AEREHEREEFQQEIQRLEGQLRQAARPRPPGPRDSQCVQLDEEVELLQEKLREKLDGFNELVIKKDFADQQLLIQEEEIK 437
Cdd:COG1196 606 SDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELA 685
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 438 RLEETNASIQRQMVQLQEELEKQKKSMEELKEKEILKQENMGDLLLTTVSRSGLDEAgcpMLPQGSSSRGPEAQPDVTER 517
Cdd:COG1196 686 ERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELL---EEEELLEEEALEELPEPPDL 762
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 518 ALLQHENEVVHRRNSE--------IDELKSLIENLQENQRQLQkDKAEEIEQLHEVIEKL 569
Cdd:COG1196 763 EELERELERLEREIEAlgpvnllaIEEYEELEERYDFLSEQRE-DLEEARETLEEAIEEI 821
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
1297-1651 |
1.27e-09 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 63.80 E-value: 1.27e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 1297 RRQVELLAYKVEQEKCIANELQKTLSKEQETASDVRKRLVVEQNAVQDLKSELHACKQENTSLLESLDKVQQEVLRLRyg 1376
Cdd:COG1196 224 ELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLE-- 301
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 1377 hvtwsycgtssasAGRAVLDGKEKELKVVLEELESERGKGQALQAQQEEQQLRYLQREGQSSRALEELKLSLEKQLAQNN 1456
Cdd:COG1196 302 -------------QDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALL 368
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 1457 QLCVALKHERAAKDNLQKELQIEASRCEALLAQEKGQLSELQKSLEAERSRSLELSEALQHERLLTEQLSRNSQEACARQ 1536
Cdd:COG1196 369 EAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAA 448
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 1537 ETQVQHALLRKLKAEKTRALELEAMLEKVQKQAAHTQQQLEAQAQErcVELRREKEVSGNLRSAVDALRTHKQELGC-CL 1615
Cdd:COG1196 449 EEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLL--LLLEAEADYEGFLEGVKAALLLAGLRGLAgAV 526
|
330 340 350
....*....|....*....|....*....|....*.
gi 1039732412 1616 QREREKAAWLQAELEQLSARVKEQEARKDARRMERR 1651
Cdd:COG1196 527 AVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAA 562
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
214-705 |
1.48e-09 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 63.42 E-value: 1.48e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 214 KKEESEQQL------ILELEDLRKQLqqaARELLTLKEEKSVLwNQKETLTNEAKEREAgspvlpahkdtalqeeveSLT 287
Cdd:COG1196 173 RKEEAERKLeateenLERLEDILGEL---ERQLEPLERQAEKA-ERYRELKEELKELEA------------------ELL 230
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 288 RVQWESRkqsEKDRATLLSQMRVLESELEDQLVQHRgcaQLAEEVATLKQQLAALDKHLRSQRQfmddqaaerehEREEF 367
Cdd:COG1196 231 LLKLREL---EAELEELEAELEELEAELEELEAELA---ELEAELEELRLELEELELELEEAQA-----------EEYEL 293
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 368 QQEIQRLEGQLRQAARPRppGPRDSQCVQLDEEVELLQEKLREKLDGFNELVIKKDFADQQLLIQEEEIKRLEETNASIQ 447
Cdd:COG1196 294 LAELARLEQDIARLEERR--RELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAE 371
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 448 RQMVQLQEELEKQKKSMEELKEKEILKQENMGDLLLTTVSRSGLDEAgcpMLPQGSSSRGPEAQPDVTERALLQHENEVV 527
Cdd:COG1196 372 AELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLER---LEEELEELEEALAELEEEEEEEEEALEEAA 448
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 528 HRRNSEIDELKSLIENLQENQRQLQKDKAEEIEQLHEVIEKLQSELSLMGPKVHEVSDPQAGSLHSELACLRG-EGLGGQ 606
Cdd:COG1196 449 EEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGlAGAVAV 528
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 607 ALRSELQAAQAAKEVFGQLLADQAHGHSQALEALQQRLQDA----------EEVAARHLAELEHCVALREAEVEAMASQI 676
Cdd:COG1196 529 LIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAkagratflplDKIRARAALAAALARGAIGAAVDLVASDL 608
|
490 500
....*....|....*....|....*....
gi 1039732412 677 QEFAATLKAKEAIIEQRDLEIDAVNKWKV 705
Cdd:COG1196 609 READARYYVLGDTLLGRTLVAARLEAALR 637
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
207-572 |
1.65e-09 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 63.54 E-value: 1.65e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 207 DLQEALGKKEESEQQLILELEDLRKQLQQAARELLTLKEEKSVLwNQKETLTNEAKEREAGSPVLPAHKDTALQEEVESL 286
Cdd:TIGR02168 681 ELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEEL-SRQISALRKDLARLEAEVEQLEERIAQLSKELTEL 759
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 287 TRVQWESRKQSEKDRATLLSQMRVLESELEDQLVQHRGCAQLAEEVATLKQQLAALDKHLRSQRQFMDDQAAEREHEree 366
Cdd:TIGR02168 760 EAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAAT--- 836
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 367 fQQEIQRLEGQLRQAArprppgprdSQCVQLDEEVELLQEKLREKLDGFNELVIKKDFADQQLLIQEEEIKRLEETNASI 446
Cdd:TIGR02168 837 -ERRLEDLEEQIEELS---------EDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELREL 906
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 447 QRQMVQLQEELEKQKKSMEELKEKEIlKQENMGDLLLTTVSRSGLDEAGcpmlPQGSSSRGPEAQPDVTERALLQHENEV 526
Cdd:TIGR02168 907 ESKRSELRRELEELREKLAQLELRLE-GLEVRIDNLQERLSEEYSLTLE----EAEALENKIEDDEEEARRRLKRLENKI 981
|
330 340 350 360
....*....|....*....|....*....|....*....|....*....
gi 1039732412 527 VHRRN---SEIDELKSLIENLQENQRQlQKDKAEEIEQLHEVIEKLQSE 572
Cdd:TIGR02168 982 KELGPvnlAAIEEYEELKERYDFLTAQ-KEDLTEAKETLEEAIEEIDRE 1029
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
1167-1693 |
5.94e-09 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 61.49 E-value: 5.94e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 1167 QALSEVTTDKGEKESLETHLTWSEELLRAIQEVFAREQEKAELQprpygsnLGDYNSLVQRLEKVIQEQgDPQKVQDHLC 1246
Cdd:COG1196 243 ELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEA-------QAEEYELLAELARLEQDI-ARLEERRREL 314
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 1247 LSDRSSLLAEIQALRAQLRMTH---LQNQEKLQQLCAALTSTEARGSQREHQLRRQVELLAYKVEQEKcianELQKTLSK 1323
Cdd:COG1196 315 EERLEELEEELAELEEELEELEeelEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELE----ELAEELLE 390
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 1324 EQETASDVRKRLVVEQNAVQDLKSELHACKQENTSLLESLDKVQQEVLRLRyghvtwsycgtsSASAGRAVLDGKEKELK 1403
Cdd:COG1196 391 ALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEE------------EALEEAAEEEAELEEEE 458
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 1404 VVLEELESERGKGQALQAQQEEQQLRYLQREGQSSRALEELKLSLE-------KQLAQNNQLCVALKHERAAKDNLQKEL 1476
Cdd:COG1196 459 EALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEgflegvkAALLLAGLRGLAGAVAVLIGVEAAYEA 538
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 1477 QIEASRCEALLAQEKGQLSELQKSLEAERSRSLELSEALQHERLLTEQLSRNSQEACARQETQVQHALLRKLKAEKTRAL 1556
Cdd:COG1196 539 ALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVL 618
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 1557 ELEAMLEKVQKQAAHTQQQLEAQAQERCVELRREKEVSGNLRSAVDALRTHKQELGCCLQREREKAAWLQAELEQLSARV 1636
Cdd:COG1196 619 GDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEA 698
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 1637 KEQEARKDARRMERRSSRADLDKRKWQRDKETLRELEIQRQRD------------------------EHKIEQLQRLVRE 1692
Cdd:COG1196 699 LLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELleeeelleeealeelpeppdleelERELERLEREIEA 778
|
.
gi 1039732412 1693 L 1693
Cdd:COG1196 779 L 779
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
1438-1698 |
9.06e-08 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 57.76 E-value: 9.06e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 1438 SRALEELKLSLEKQLAQNNQLCVALKHERAAKDNLQKE---LQIEASRCEALLAQEKGQLSELQKSLEAERSR----SLE 1510
Cdd:TIGR02168 676 RREIEELEEKIEELEEKIAELEKALAELRKELEELEEEleqLRKELEELSRQISALRKDLARLEAEVEQLEERiaqlSKE 755
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 1511 LSEALQHERLLTEQLSRNSQEACARQETQVQhaLLRKLKAEKTRALELEAMLEKVQKQAAHTQqqleaqaqercVELRRE 1590
Cdd:TIGR02168 756 LTELEAEIEELEERLEEAEEELAEAEAEIEE--LEAQIEQLKEELKALREALDELRAELTLLN-----------EEAANL 822
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 1591 KEVSGNLRSAVDALRTHKQELGCCLQREREKAAWLQAELEQLSARVKEQEARKDARRMERRSSRADLDKRKWQRDK--ET 1668
Cdd:TIGR02168 823 RERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEElsEE 902
|
250 260 270
....*....|....*....|....*....|
gi 1039732412 1669 LRELEIQRQRDEHKIEQLQRLVRELRWKEE 1698
Cdd:TIGR02168 903 LRELESKRSELRRELEELREKLAQLELRLE 932
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
214-648 |
2.65e-07 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 56.22 E-value: 2.65e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 214 KKEESEQQLILELEDLrKQLQQAARELltlkeEKsvlwnQKETLTNEAKEreagspvlpAHKDTALQEEVESLTRVQWES 293
Cdd:TIGR02168 173 RRKETERKLERTRENL-DRLEDILNEL-----ER-----QLKSLERQAEK---------AERYKELKAELRELELALLVL 232
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 294 RKQSEKDRatlLSQMRVLESELEDQlvqhrgCAQLAEEVATLKQQLAALdkhlRSQRQFMDDQAAEREHEREEFQQEIQR 373
Cdd:TIGR02168 233 RLEELREE---LEELQEELKEAEEE------LEELTAELQELEEKLEEL----RLEVSELEEEIEELQKELYALANEISR 299
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 374 LEGQLRqaarprppgprdsqcvqldeeveLLQEKLREKLDGFNELVIKKDFADQQLLIQEEEIKRLEETNASIQRQMVQL 453
Cdd:TIGR02168 300 LEQQKQ-----------------------ILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESL 356
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 454 QEELEKQKKSMEELKEKEILKQENMGDLllttvsrsgldeagcpmlpqgsssrgpeaqpdvtERALLQHENEvVHRRNSE 533
Cdd:TIGR02168 357 EAELEELEAELEELESRLEELEEQLETL----------------------------------RSKVAQLELQ-IASLNNE 401
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 534 IDELKSLIENLQENQRQLQKDKAEEIEQLHEV-IEKLQSELslmgpkvhevsdpqaGSLHSELACLRGEGLGGQALRSEL 612
Cdd:TIGR02168 402 IERLEARLERLEDRRERLQQEIEELLKKLEEAeLKELQAEL---------------EELEEELEELQEELERLEEALEEL 466
|
410 420 430
....*....|....*....|....*....|....*.
gi 1039732412 613 QAAQAAKEVFGQLLADQAHGHSQALEALQQRLQDAE 648
Cdd:TIGR02168 467 REELEEAEQALDAAERELAQLQARLDSLERLQENLE 502
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
124-467 |
3.97e-07 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 55.45 E-value: 3.97e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 124 LSTAVEGLLEMALDSSKQLEEARQLHRCVEREFRHRNEEMAQAMQKQQELLERLREESAAKDRLALELHTAKGLLEGFKV 203
Cdd:TIGR02168 682 LEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEA 761
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 204 EKVDLQEALGKKE----------ESEQQLIL----ELEDLRKQLQQAARELLTLKEEKSVLWNQKETLTNEAKEREAGSP 269
Cdd:TIGR02168 762 EIEELEERLEEAEeelaeaeaeiEELEAQIEqlkeELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLE 841
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 270 VLPAHKDTaLQEEVESLTrvqwESRKQSEKDRATLLSQmrvLESELEDQLVQHRGCAQLAEEVATLKQQLAALDKH---L 346
Cdd:TIGR02168 842 DLEEQIEE-LSEDIESLA----AEIEELEELIEELESE---LEALLNERASLEEALALLRSELEELSEELRELESKrseL 913
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 347 RSQRQFMDDQAAEREHEREEFQQEIQRLEGQLRQAAR------PRPPGPRDSQCVQLDEEVELLQEKLrEKLDGFNELVI 420
Cdd:TIGR02168 914 RRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSltleeaEALENKIEDDEEEARRRLKRLENKI-KELGPVNLAAI 992
|
330 340 350 360
....*....|....*....|....*....|....*....|....*..
gi 1039732412 421 kkdfadqqlliqeEEIKRLEETNASIQRQMVQLQEELEKQKKSMEEL 467
Cdd:TIGR02168 993 -------------EEYEELKERYDFLTAQKEDLTEAKETLEEAIEEI 1026
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
168-466 |
4.53e-07 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 55.46 E-value: 4.53e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 168 QKQQELLERLREESAAKDRLALELHTAKGLLEGFKVEKVDLQEALGKKEESEQQLIL-ELEDLRKQLQQAARELLTLKEE 246
Cdd:TIGR02169 173 EKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAERYQALLKEKREYEGYELLkEKEALERQKEAIERQLASLEEE 252
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 247 KSVLWNQKETLTNEAKEREA------------GSPVLPAHKDT--ALQEEVESLTRVQWES----------RKQSEKDRA 302
Cdd:TIGR02169 253 LEKLTEEISELEKRLEEIEQlleelnkkikdlGEEEQLRVKEKigELEAEIASLERSIAEKereledaeerLAKLEAEID 332
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 303 TLLSQMRVLESELEDQLVQHRGC----AQLAEEVATLKQQLAALDKHLRSQRQFMDD----------QAAEREHEREEFQ 368
Cdd:TIGR02169 333 KLLAEIEELEREIEEERKRRDKLteeyAELKEELEDLRAELEEVDKEFAETRDELKDyrekleklkrEINELKRELDRLQ 412
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 369 QEIQRLEGQLRQAaRPRPPGPRDSQcVQLDEEVELLQEKLREKLDGFNELVIKKDFADQQLLIQEEEIKRLEETNASIQR 448
Cdd:TIGR02169 413 EELQRLSEELADL-NAAIAGIEAKI-NELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQR 490
|
330
....*....|....*...
gi 1039732412 449 QMvqlqEELEKQKKSMEE 466
Cdd:TIGR02169 491 EL----AEAEAQARASEE 504
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
139-691 |
1.01e-06 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 54.28 E-value: 1.01e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 139 SKQLEEARQLHRCVEREFRHRNEEMAQAMQKQQELLERLREESAAKDRLALElhTAKGLLEGFKVEKVDLQEALGKKEES 218
Cdd:TIGR00606 446 KEILEKKQEELKFVIKELQQLEGSSDRILELDQELRKAERELSKAEKNSLTE--TLKKEVKSLQNEKADLDRKLRKLDQE 523
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 219 EQQLILELEDLRKQLQQAARELLTLKEEKSVLWNQKETLTNEAKEreagSPVLPAHKDT----------------ALQEE 282
Cdd:TIGR00606 524 MEQLNHHTTTRTQMEMLTKDKMDKDEQIRKIKSRHSDELTSLLGY----FPNKKQLEDWlhskskeinqtrdrlaKLNKE 599
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 283 VESLTRVQWESRKQSEKDRATLLSqmrvleseLEDQLVQHRGC-------AQLAEEVATLKQQLAALDKHLRSQRQFMDD 355
Cdd:TIGR00606 600 LASLEQNKNHINNELESKEEQLSS--------YEDKLFDVCGSqdeesdlERLKEEIEKSSKQRAMLAGATAVYSQFITQ 671
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 356 QAAERE------HEREEFQQEIQRLEGQLRQAARPRPpgprdsqcvqldEEVELLQEKLREKLDGFNELVIKKDFADQQL 429
Cdd:TIGR00606 672 LTDENQsccpvcQRVFQTEAELQEFISDLQSKLRLAP------------DKLKSTESELKKKEKRRDEMLGLAPGRQSII 739
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 430 LIQEEEIKRLEETNASIQRQMVQLQEELEKQKKSMEELKEKEILKQENMGDLLLTTVSRSGLDEAGCPMLPQGSSSRGPE 509
Cdd:TIGR00606 740 DLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTIMPEEESAKVCLTDVTIMERFQMELKDVERKIAQQAAKLQGSD 819
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 510 AQPDVTE-RALLQHENEVVHRRNSEIDELKSLIENLQENQRQLQKD----KAEEI-------------EQLHEVIEKLQS 571
Cdd:TIGR00606 820 LDRTVQQvNQEKQEKQHELDTVVSKIELNRKLIQDQQEQIQHLKSKtnelKSEKLqigtnlqrrqqfeEQLVELSTEVQS 899
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 572 ELSLMGPKVHEVSdPQAGSLHSELAclRGEGLGGQALRSELQAAQAAKEVFGQLlaDQAHGHSQALEALQQ-----RLQD 646
Cdd:TIGR00606 900 LIREIKDAKEQDS-PLETFLEKDQQ--EKEELISSKETSNKKAQDKVNDIKEKV--KNIHGYMKDIENKIQdgkddYLKQ 974
|
570 580 590 600
....*....|....*....|....*....|....*....|....*
gi 1039732412 647 AEEVAARHLAELEHCVALREAEVEAMASQIQEFaATLKAKEAIIE 691
Cdd:TIGR00606 975 KETELNTVNAQLEECEKHQEKINEDMRLMRQDI-DTQKIQERWLQ 1018
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
1256-1699 |
1.02e-06 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 54.38 E-value: 1.02e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 1256 EIQALRAQLRMTHLQNQEKLQQLCAALTSTEARGSQ--REHQLRRQVE-----LLAYKVEQEKCI-----ANELQKtlSK 1323
Cdd:PTZ00121 1114 ARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAEdaKRVEIARKAEdarkaEEARKAEDAKKAeaarkAEEVRK--AE 1191
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 1324 EQETASDVRK----RLVVEQNAVQDLKSELHACKQENTSLLESLDKVQQEVLR---LRYGHVTWSYCGTSSASAGRAVLD 1396
Cdd:PTZ00121 1192 ELRKAEDARKaeaaRKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKaeeERNNEEIRKFEEARMAHFARRQAA 1271
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 1397 GKEKELKVVlEELE--SERGKGQALQAQQEEQQLRYLQREGQSSRALEELKLSLEKQLAQNNQLcvALKHERAAKDNLQK 1474
Cdd:PTZ00121 1272 IKAEEARKA-DELKkaEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAA--KKKAEEAKKAAEAA 1348
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 1475 ELQIEASRCEALLAQEKGQLSELQKSLEAERSRSLELSealQHERLLTEQLSRNSQEACARQETqvqhalLRKLKAEKTR 1554
Cdd:PTZ00121 1349 KAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKK---AEEKKKADEAKKKAEEDKKKADE------LKKAAAAKKK 1419
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 1555 ALELEAMLEKVQKQAAHTQQQLEAQAQERCVELRREKEVSGNLRSAVDALRthKQELGCCLQREREKAAWLQAELEQlsA 1634
Cdd:PTZ00121 1420 ADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAK--KADEAKKKAEEAKKADEAKKKAEE--A 1495
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1039732412 1635 RVKEQEARKDArrmERRSSRADLDKRKWQRDKETLRELEIQRQRDEHKIEQLQRLVRELRWKEEV 1699
Cdd:PTZ00121 1496 KKKADEAKKAA---EAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEEL 1557
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
140-463 |
1.55e-06 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 53.53 E-value: 1.55e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 140 KQLEEARQLHRCVEREFRHRNEEMAQAMQKQQELLERLREESAAKDRLALELHTAKGLLEGFKVEKVDLQEALGKKEESE 219
Cdd:TIGR02169 702 NRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEAL 781
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 220 QQliLELEDLRKQLQQAARELLTLKEEKSVLwnqkETLTNEAKEREAGSPVLPAHKDTALQEEVESltRVQWESRKQSEK 299
Cdd:TIGR02169 782 ND--LEARLSHSRIPEIQAELSKLEEEVSRI----EARLREIEQKLNRLTLEKEYLEKEIQELQEQ--RIDLKEQIKSIE 853
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 300 DRATLL-SQMRVLESELEDQLVQHRgcaQLAEEVATLKQQLAALDKHLRSQRQFMDD---QAAEREHEREEFQQEIQRLE 375
Cdd:TIGR02169 854 KEIENLnGKKEELEEELEELEAALR---DLESRLGDLKKERDELEAQLRELERKIEEleaQIEKKRKRLSELKAKLEALE 930
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 376 GQLRQAARPRPPGPRDSQCVQLDEEVELLQEKLREKLDGFNELVIKkdfADQQLLIQEEEIKRLEETNASIQRQMVQLQ- 454
Cdd:TIGR02169 931 EELSEIEDPKGEDEEIPEEELSLEDVQAELQRVEEEIRALEPVNML---AIQEYEEVLKRLDELKEKRAKLEEERKAILe 1007
|
330
....*....|.
gi 1039732412 455 --EELEKQKKS 463
Cdd:TIGR02169 1008 riEEYEKKKRE 1018
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
1398-1698 |
2.93e-06 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 52.67 E-value: 2.93e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 1398 KEKELKVVLEELESERgkgqALQAQQEEQQLRYLQREGQSSRALEELKLSLEKQLAQNNQLCVA-LKHERAAKDNLQKEL 1476
Cdd:pfam02463 171 KKEALKKLIEETENLA----ELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDyLKLNEERIDLLQELL 246
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 1477 QIEASRCEALLAQEKGQLSELQKSLEAERSRslELSEALQHERLLTEQLSRNSQEACARQETQVQHALLRKLKAEKTRAL 1556
Cdd:pfam02463 247 RDEQEEIESSKQEIEKEEEKLAQVLKENKEE--EKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKK 324
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 1557 ELEAMLEKVQKQAAHTQQQLEAQAQERCVELRREKEVSGNLRSAVDALRTHKQELgcCLQREREKAAwlqAELEQLSARV 1636
Cdd:pfam02463 325 KAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKK--KLESERLSSA---AKLKEEELEL 399
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1039732412 1637 KEQEARKDARRMERRSSRADLDKRKWQRDKETLRELEIQRQRDEHKIEQLQRLVRELRWKEE 1698
Cdd:pfam02463 400 KSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLL 461
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
1461-1694 |
4.60e-06 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 51.30 E-value: 4.60e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 1461 ALKHERAAKDNLQKELQIEASRCEALLAQEKGQLSELQKSLEAERSRSLELSEALQHERLLTEQLSRNSQEacarqetqv 1540
Cdd:COG4942 21 AAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKE--------- 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 1541 QHALLRKLKAEKTRALELEAMLEKVQKQAAHTQQQLEAQAQERCVELRREKEVSGNLRSAVDALRTHKQELgcclQRERE 1620
Cdd:COG4942 92 IAELRAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAEL----AALRA 167
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1039732412 1621 KAAWLQAELEQLSARVKEQEARKDARRMERRSSRADLDKRKwQRDKETLRELEIQRQRDEHKIEQLQRLVRELR 1694
Cdd:COG4942 168 ELEAERAELEALLAELEEERAALEALKAERQKLLARLEKEL-AELAAELAELQQEAEELEALIARLEAEAAAAA 240
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
133-377 |
7.14e-06 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 51.45 E-value: 7.14e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 133 EMALDSSKQLEEARQLhrcVErEFR--HRNEEMAQAMQKQQELLERLREESAAKDRLALELHTAKGLLEGFKVEKvdLQE 210
Cdd:COG4913 215 EYMLEEPDTFEAADAL---VE-HFDdlERAHEALEDAREQIELLEPIRELAERYAAARERLAELEYLRAALRLWF--AQR 288
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 211 ALGKKEESEQQLILELEDLRKQLQQAARELLTLKEEKSVLWNQKETLTNEAKEReagspvlpahkdtaLQEEVESLTRvq 290
Cdd:COG4913 289 RLELLEAELEELRAELARLEAELERLEARLDALREELDELEAQIRGNGGDRLEQ--------------LEREIERLER-- 352
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 291 weSRKQSEKDRATLLSQMRVLESEL---EDQLVQHRgcAQLAEEVATLKQQLAALDKHLRSQRqfmdDQAAEREHEREEF 367
Cdd:COG4913 353 --ELEERERRRARLEALLAALGLPLpasAEEFAALR--AEAAALLEALEEELEALEEALAEAE----AALRDLRRELREL 424
|
250
....*....|
gi 1039732412 368 QQEIQRLEGQ 377
Cdd:COG4913 425 EAEIASLERR 434
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
168-572 |
1.25e-05 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 50.40 E-value: 1.25e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 168 QKQQELLERLREESAAKDRLALELHTAKGLLEGFKVEKVDLQEALGKKEESEQQLILELEDLRKQLQQAARELLTLKEEK 247
Cdd:TIGR04523 225 KQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISDLNNQK 304
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 248 SVLWNQ--KETLTNEAKE-REAGSPVLPAHKD-TALQEEVESLTRvqweSRKQSEKDRATLLSQMRVLESELEDQLVQHr 323
Cdd:TIGR04523 305 EQDWNKelKSELKNQEKKlEEIQNQISQNNKIiSQLNEQISQLKK----ELTNSESENSEKQRELEEKQNEIEKLKKEN- 379
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 324 gcAQLAEEVATLKQQLAALDKHLRSQR---QFMDDQAAEREHEREEFQQEIQRLEgqlrqaarprppgprdSQCVQLDEE 400
Cdd:TIGR04523 380 --QSYKQEIKNLESQINDLESKIQNQEklnQQKDEQIKKLQQEKELLEKEIERLK----------------ETIIKNNSE 441
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 401 VELLQEKLREKLDGFNELVIKKDfadqqllIQEEEIKRLEETNASIQRQMVQLQEELEKQKKSMEELKEKEILKQENMGD 480
Cdd:TIGR04523 442 IKDLTNQDSVKELIIKNLDNTRE-------SLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKD 514
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 481 LLlttvsrsgldeagcpmlPQGSSSRgpeaqpdVTERALlqhENEVVhRRNSEIDELKSLIENLQEN--QRQLQK---DK 555
Cdd:TIGR04523 515 LT-----------------KKISSLK-------EKIEKL---ESEKK-EKESKISDLEDELNKDDFElkKENLEKeidEK 566
|
410
....*....|....*..
gi 1039732412 556 AEEIEQLHEVIEKLQSE 572
Cdd:TIGR04523 567 NKEIEELKQTQKSLKKK 583
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
1385-1642 |
1.92e-05 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 50.06 E-value: 1.92e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 1385 TSSASAGRAVLDGKEKELKVVLEELESERGKGQALQAQQEEQQLRYLQREGQSSRaleelklsLEKQLAQNNQLCVALKH 1464
Cdd:TIGR02168 690 EEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQ--------LEERIAQLSKELTELEA 761
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 1465 ERAAKDNLQKELQIEASRCEALLAQEKGQLSELQKSLEAERSRSLELSEALQ------HERLLTEQLSRNSQEACARQ-- 1536
Cdd:TIGR02168 762 EIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTllneeaANLRERLESLERRIAATERRle 841
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 1537 ETQVQHALLRKLKAEKTRALE-LEAMLEKVQKQAAHTQQQLEAQAQERcVELRREKEvsgNLRSAVDALRTHKQELGCCL 1615
Cdd:TIGR02168 842 DLEEQIEELSEDIESLAAEIEeLEELIEELESELEALLNERASLEEAL-ALLRSELE---ELSEELRELESKRSELRREL 917
|
250 260
....*....|....*....|....*..
gi 1039732412 1616 QREREKAAWLQAELEQLSARVKEQEAR 1642
Cdd:TIGR02168 918 EELREKLAQLELRLEGLEVRIDNLQER 944
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
283-687 |
2.19e-05 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 49.77 E-value: 2.19e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 283 VESLTRVQWESRKQSEKDRATLLSQMRVLESELEDQLVQHRGCAQLAEEVATLKQQLAALD---KHLRSQRQFMDD--QA 357
Cdd:COG4717 48 LERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEaelEELREELEKLEKllQL 127
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 358 AEREHEREEFQQEIQRLEGQLRQA-ARPRPPGPRDSQCVQLDEEVELLQEKLREKLDGFNeLVIKKDFADQQLLIQE--E 434
Cdd:COG4717 128 LPLYQELEALEAELAELPERLEELeERLEELRELEEELEELEAELAELQEELEELLEQLS-LATEEELQDLAEELEElqQ 206
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 435 EIKRLEETNASIQRQMVQLQEELEKQKKSMEELKEKEILKQE---------------NMGDLLLTTVSRSGLDEAGCPML 499
Cdd:COG4717 207 RLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEArlllliaaallallgLGGSLLSLILTIAGVLFLVLGLL 286
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 500 PQGSSSRGPEAQPDVTERALLQHENEVVHRRNSEIDELKS---LIENLQENQRQLQKDKAEEIEQLHEVIEKLQSELSLM 576
Cdd:COG4717 287 ALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAalgLPPDLSPEELLELLDRIEELQELLREAEELEEELQLE 366
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 577 GPKVHEVSDPQAGSLHSElaclrgeglggQALRSELQAAQAAKEVFGQLLADQAHGHSQALEALQQRLQDAEEVAARHLA 656
Cdd:COG4717 367 ELEQEIAALLAEAGVEDE-----------EELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEELEEELE 435
|
410 420 430
....*....|....*....|....*....|.
gi 1039732412 657 ELEHCVALREAEVEAMASQIQEFAATLKAKE 687
Cdd:COG4717 436 ELEEELEELEEELEELREELAELEAELEQLE 466
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
1164-1650 |
2.20e-05 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 49.94 E-value: 2.20e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 1164 RDSQALSEVTTDKGEKESLETHL-TWSEELLRAIQEVFAREQEKAELQprpygsnlGDYNSLVQRLEKVIQEQGDPQKVQ 1242
Cdd:COG1196 310 RRRELEERLEELEEELAELEEELeELEEELEELEEELEEAEEELEEAE--------AELAEAEEALLEAEAELAEAEEEL 381
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 1243 DHLcLSDRSSLLAEIQALRAQLRMTHLQNQEKLQQLCAALTSTEARGSQREHQLRRQVELLAYKVEQEKCIANELQKTLS 1322
Cdd:COG1196 382 EEL-AEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEA 460
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 1323 KEQETASDVRKRLVVEQnAVQDLKSELHACKQENTSLLESLDKVQQEVLRLRYGHVTWSYCGtsSASAGRAVLDGKEKEL 1402
Cdd:COG1196 461 LLELLAELLEEAALLEA-ALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRG--LAGAVAVLIGVEAAYE 537
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 1403 KVVLEELESERGKGQALQAQQEEQQLRYLQREGQSSRALEELKLSLEKQLAQNNQLCVALKHERAAKDNLQKELQIEASR 1482
Cdd:COG1196 538 AALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYV 617
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 1483 CEALLAQEkgqlSELQKSLEAERSRSLELSEALQHERLLTEQLSRNSQEAcaRQETQVQHALLRKLKAEKTRALELEAML 1562
Cdd:COG1196 618 LGDTLLGR----TLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLT--GGSRRELLAALLEAEAELEELAERLAEE 691
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 1563 EKVQKQAAHTQQQLEAQAQERCVELRREKEVSGNLRSAVDALRTHKQELgccLQREREKAAWLQAELEQLSARVKEQEAR 1642
Cdd:COG1196 692 ELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEE---LLEEEELLEEEALEELPEPPDLEELERE 768
|
490
....*....|
gi 1039732412 1643 KDA--RRMER 1650
Cdd:COG1196 769 LERleREIEA 778
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
122-470 |
2.91e-05 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 49.27 E-value: 2.91e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 122 QSLSTAVEGLLEMALDSSKQLEEARQLHRCVEREFRHRNEEMAQAMQKQQELLERLREESAAKDRLALELHTAKGLLEGF 201
Cdd:PRK02224 338 QAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEEL 417
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 202 KVEK-----------VDLQEALGKKEESEQQL-----------------ILELEDLRKQLQQAARELLTLKEEKSVLWNQ 253
Cdd:PRK02224 418 REERdelrereaeleATLRTARERVEEAEALLeagkcpecgqpvegsphVETIEEDRERVEELEAELEDLEEEVEEVEER 497
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 254 KETLTnEAKEREAGSpvlpahkdTALQEEVESLTRVQWESRKQSEKDRATlLSQMRVLESELEDQLVQHRGCAQLA---- 329
Cdd:PRK02224 498 LERAE-DLVEAEDRI--------ERLEERREDLEELIAERRETIEEKRER-AEELRERAAELEAEAEEKREAAAEAeeea 567
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 330 ----EEVATLKQQLAALDKHLRSQRQFMDDQaaereHEREEFQQEIQRLEGQLRQAARprppgprdsqcvQLDEEVELLQ 405
Cdd:PRK02224 568 eearEEVAELNSKLAELKERIESLERIRTLL-----AAIADAEDEIERLREKREALAE------------LNDERRERLA 630
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1039732412 406 EK------LREKLDG--FNELVIKKDFADQQLLIQEEEIKRLEETNASIQRQMVQLQEELEkqkkSMEELKEK 470
Cdd:PRK02224 631 EKrerkreLEAEFDEarIEEAREDKERAEEYLEQVEEKLDELREERDDLQAEIGAVENELE----ELEELRER 699
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
273-682 |
3.43e-05 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 49.07 E-value: 3.43e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 273 AHKDTALQEEVESLTRVQWE------SRKQSEKDRATLLSQMRVLESELEDQLVQHRgcAQLAEEVATLKQQLAALD--- 343
Cdd:pfam12128 240 RPEFTKLQQEFNTLESAELRlshlhfGYKSDETLIASRQEERQETSAELNQLLRTLD--DQWKEKRDELNGELSAADaav 317
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 344 KHLRSQRQFMDDQAAErehereeFQQE-IQRLEGQLRQAARPRppgprdSQCVQLDEEVELLQEKLREKLDGFNELVIK- 421
Cdd:pfam12128 318 AKDRSELEALEDQHGA-------FLDAdIETAAADQEQLPSWQ------SELENLEERLKALTGKHQDVTAKYNRRRSKi 384
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 422 --------KDFADQQLLIQEEEIKRLEETNASIQRQMVQLQEELEKQKKsmeELKEKEILKQENMGDLllttvsrsglde 493
Cdd:pfam12128 385 keqnnrdiAGIKDKLAKIREARDRQLAVAEDDLQALESELREQLEAGKL---EFNEEEYRLKSRLGEL------------ 449
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 494 agcpmlpqgsssRGPEAQPDVTERALLQHEN--EVVHRRNSEIDELKSLIENLQENQRQLQK--DKAEE-IEQLHEVIEK 568
Cdd:pfam12128 450 ------------KLRLNQATATPELLLQLENfdERIERAREEQEAANAEVERLQSELRQARKrrDQASEaLRQASRRLEE 517
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 569 LQSELSlmgpKVHEVSDPQAGSLHSELA------------CLRGEGLGGQALRSELQAAQAAKE--VFG------QLLAD 628
Cdd:pfam12128 518 RQSALD----ELELQLFPQAGTLLHFLRkeapdweqsigkVISPELLHRTDLDPEVWDGSVGGElnLYGvkldlkRIDVP 593
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....
gi 1039732412 629 QAHGHSQALEALQQRLQDAEEVAARHLAELEHCVALREAEVEAmASQIQEFAAT 682
Cdd:pfam12128 594 EWAASEEELRERLDKAEEALQSAREKQAAAEEQLVQANGELEK-ASREETFART 646
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
140-670 |
5.93e-05 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 48.43 E-value: 5.93e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 140 KQLEEARQLHRCVEREFRHRNEEMAQAMQKQQELLERLREE----------SAAKDRLALELHTAKGLLEGFKVEKVDLQ 209
Cdd:TIGR00618 229 KHLREALQQTQQSHAYLTQKREAQEEQLKKQQLLKQLRARIeelraqeavlEETQERINRARKAAPLAAHIKAVTQIEQQ 308
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 210 EA-----LGKKEESEQQLILELEDLRKQ---LQQAARELLTL--KEEKSVLWNQKETLTNEAKEREAGSpvlpAHKDTAL 279
Cdd:TIGR00618 309 AQrihteLQSKMRSRAKLLMKRAAHVKQqssIEEQRRLLQTLhsQEIHIRDAHEVATSIREISCQQHTL----TQHIHTL 384
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 280 QEEVESLTRVQWESRKQSEKDR------ATLLSQMRVLESEL----EDQLVQHRGCAQLAEEVATLKQQLAALDKHLRSQ 349
Cdd:TIGR00618 385 QQQKTTLTQKLQSLCKELDILQreqatiDTRTSAFRDLQGQLahakKQQELQQRYAELCAAAITCTAQCEKLEKIHLQES 464
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 350 RQFMDDQAAEREHEREEFQQ--EIQRLEGQ--LRQAARPRP-----------------PGPRDSQCVQLDEEVELLQE-- 406
Cdd:TIGR00618 465 AQSLKEREQQLQTKEQIHLQetRKKAVVLArlLELQEEPCPlcgscihpnparqdidnPGPLTRRMQRGEQTYAQLETse 544
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 407 -----KLREKLDGFNELVIKKDFADQQLLIQEEEIKRLEETNASIQRQMVQLQEELEKQ---KKSMEELKEKEILKQENM 478
Cdd:TIGR00618 545 edvyhQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLseaEDMLACEQHALLRKLQPE 624
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 479 GDLLLTTVSRSGLDEAGCPMLPQGSSSRGPEAQPDVTERALL--QHENEVVHRRNSEIDELKSLIenlqenqRQLQKDKa 556
Cdd:TIGR00618 625 QDLQDVRLHLQQCSQELALKLTALHALQLTLTQERVREHALSirVLPKELLASRQLALQKMQSEK-------EQLTYWK- 696
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 557 EEIEQLHEVIEKLQSELSLMGPKVHEVSDpqagSLHSELACLRGEGLGGQALRSELQAAQaaKEVFGQLLADQAHGHSQA 636
Cdd:TIGR00618 697 EMLAQCQTLLRELETHIEEYDREFNEIEN----ASSSLGSDLAAREDALNQSLKELMHQA--RTVLKARTEAHFNNNEEV 770
|
570 580 590
....*....|....*....|....*....|....*....
gi 1039732412 637 LEALQ--QRLQDAE---EVAARHLAELEHCVALREAEVE 670
Cdd:TIGR00618 771 TAALQtgAELSHLAaeiQFFNRLREEDTHLLKTLEAEIG 809
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
1218-1530 |
6.48e-05 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 48.13 E-value: 6.48e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 1218 LGDYNSLVQRLEKVIQEQGDPQKVQDHLclsdrSSLLAEIQALRAQLRMTHLQNQEKLQQLCAALTSTEARGSQREHQLR 1297
Cdd:TIGR02168 231 VLRLEELREELEELQEELKEAEEELEEL-----TAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQ 305
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 1298 RQVELLAYKVEQEKCIANELQKTLSKEQETA---SDVRKRLVVEQNAVQDLKSELHACKQENTSLLESLDKVQQEVLRLR 1374
Cdd:TIGR02168 306 ILRERLANLERQLEELEAQLEELESKLDELAeelAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLR 385
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 1375 yghvtwsyCGTSSASAGRAVLDGKEKELKVVLEELESERGKGQALQAQQEEQQLRYLQREgqSSRALEELKLSLEKQLAQ 1454
Cdd:TIGR02168 386 --------SKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKE--LQAELEELEEELEELQEE 455
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1039732412 1455 NNQLCVALKHERAAKDNLQKELQIEASRcealLAQEKGQLSELQKSLEAERSRSLELSEALQHERLLTEQLSRNSQ 1530
Cdd:TIGR02168 456 LERLEEALEELREELEEAEQALDAAERE----LAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSE 527
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
1286-1657 |
7.34e-05 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 48.21 E-value: 7.34e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 1286 EARGSQREHQLRRQVELLAYKVEqEKCIANELQKTlSKEQETASDVRKRLVVEQNAVQDLKSELHAcKQENTSLLESLDK 1365
Cdd:PTZ00121 1445 KADEAKKKAEEAKKAEEAKKKAE-EAKKADEAKKK-AEEAKKADEAKKKAEEAKKKADEAKKAAEA-KKKADEAKKAEEA 1521
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 1366 VQQEVLRlryghvtwsycgtsSASAGRAVLDGKEKELKVVLEELESERGKGQALQAQQEEQQLRYLQREGQSSRALEELK 1445
Cdd:PTZ00121 1522 KKADEAK--------------KAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAK 1587
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 1446 LSLEKQLAQNNQLCVALKHERAAKDNLQKELQIEASRCEALlAQEKGQLSELQKSLEAERSRSLELSEALQHERLLTEQL 1525
Cdd:PTZ00121 1588 KAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKA-EEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEE 1666
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 1526 SRN-------SQEACARQETQVQHALLRKLKAEKTRALELEAMLEKVQKQAAHTQQQLEAQAQERCVELRREKEVSgnlR 1598
Cdd:PTZ00121 1667 AKKaeedkkkAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEED---K 1743
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 1599 SAVDALRTHKQELGCCLQREREKAAWLQAELEQLSARVKEQEARKD-ARRMERRSSRADL 1657
Cdd:PTZ00121 1744 KKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDeKRRMEVDKKIKDI 1803
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
1255-1532 |
7.73e-05 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 48.13 E-value: 7.73e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 1255 AEIQALRAQLRMTHLQNQEKLQQLCAALTSTEARGSQRE------HQLRRQVELLAYKVEQEKCIANELQKTLSKEQETA 1328
Cdd:TIGR02168 677 REIEELEEKIEELEEKIAELEKALAELRKELEELEEELEqlrkelEELSRQISALRKDLARLEAEVEQLEERIAQLSKEL 756
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 1329 SDVRKRLVVEQNAVQDLKSELHACKQENTSLLESLDKVQQEvlrlryghvtwsycgtssASAGRAVLDGKEKELKvvleE 1408
Cdd:TIGR02168 757 TELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEE------------------LKALREALDELRAELT----L 814
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 1409 LESERGKgqalqaqQEEQQLRYLQREGQSSRALEELKLSLEKQLAQNNQLCVALKHERAAKDNLQKELQI---EASRCEA 1485
Cdd:TIGR02168 815 LNEEAAN-------LRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEAllnERASLEE 887
|
250 260 270 280
....*....|....*....|....*....|....*....|....*..
gi 1039732412 1486 LLAQEKGQLSELQKSLEAERSRSLELSEALQHERLLTEQLSRNSQEA 1532
Cdd:TIGR02168 888 ALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGL 934
|
|
| COG2433 |
COG2433 |
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only]; |
368-494 |
8.27e-05 |
|
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
Pssm-ID: 441980 [Multi-domain] Cd Length: 644 Bit Score: 47.55 E-value: 8.27e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 368 QQEIQRLEGQLRQaarprppgprdsqcvqLDEEVELLQEKLREKLDGFNELVIKKDFADQQLLIQ---EEEIKRLEETNA 444
Cdd:COG2433 412 EEEIRRLEEQVER----------------LEAEVEELEAELEEKDERIERLERELSEARSEERREirkDREISRLDREIE 475
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....
gi 1039732412 445 SIQRQMVQLQEELEKQKKSMEELkeKEILKQENMGDLL----LTTVSRSGLDEA 494
Cdd:COG2433 476 RLERELEEERERIEELKRKLERL--KELWKLEHSGELVpvkvVEKFTKEAIRRL 527
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
1226-1858 |
8.63e-05 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 48.04 E-value: 8.63e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 1226 QRLEKVIQEQGDPQKVQDHLCLSDRSSLLAEIQALRAqlrMTHLQNQEKLQQLCAALTSTEARGSQREHQLRRQVELLAY 1305
Cdd:pfam02463 173 EALKKLIEETENLAELIIDLEELKLQELKLKEQAKKA---LEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDE 249
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 1306 KVEQEKcianeLQKTLSKEQETASDVRKRLVVEQNAVQDLKSELHAC-KQENTSLLESLDKVQQEVLRLRYghvtwsycg 1384
Cdd:pfam02463 250 QEEIES-----SKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLaKEEEELKSELLKLERRKVDDEEK--------- 315
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 1385 TSSASAGRAVLDGKEKELKVVLEELESERGKGQALQAQQEEQQLRYLQREGQSSRALEELKLSLEKQLAQ--------NN 1456
Cdd:pfam02463 316 LKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERlssaaklkEE 395
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 1457 QLCVALKHERAAKDNLQkELQIEASRCEALLAQEKGQLSELQKSLEAERSRSLELSEALQHERLLTEQLSRNSQEACARQ 1536
Cdd:pfam02463 396 ELELKSEEEKEAQLLLE-LARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLL 474
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 1537 ETQVQHALLRKLKAEKTRALELEAmlekVQKQAAHTQQQLEAQAQERCVELRREKEVSGNLRSA--VDALRTHKQELGCC 1614
Cdd:pfam02463 475 KETQLVKLQEQLELLLSRQKLEER----SQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLgvAVENYKVAISTAVI 550
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 1615 LQREREKAAWLQAELEQLSARVKEQEARKDARRMERRSSRADLDkrkwqrdketlRELEIQRQRDEHKIEQLQRLVRELR 1694
Cdd:pfam02463 551 VEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSI-----------AVLEIDPILNLAQLDKATLEADEDD 619
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 1695 WKEEVSGGNGPCRgspgRGSLERDQFQEQQQELEKIRQQLLCAAGLLTSFTNHTVDRTIKDWTSSNEKAVSSLMRTLEEL 1774
Cdd:pfam02463 620 KRAKVVEGILKDT----ELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEIL 695
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 1775 KSELSMPTSFQKKMTAELQVQLMNELLSDNDALTKAVGMATREKAELCRTVSRLEKTLKHHTQKGCVLNRQSKSSLKQDG 1854
Cdd:pfam02463 696 RRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKE 775
|
....
gi 1039732412 1855 TDLQ 1858
Cdd:pfam02463 776 LAEE 779
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
132-471 |
1.03e-04 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 47.45 E-value: 1.03e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 132 LEMALDSSKQLEEAR-QLHRCVER--EFRHRNEEMAQAMQKQQELLERLREESAAKDRLALEL-HTAKGLLEGFKVEKVD 207
Cdd:COG4717 124 LLQLLPLYQELEALEaELAELPERleELEERLEELRELEEELEELEAELAELQEELEELLEQLsLATEEELQDLAEELEE 203
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 208 LQEALGKKEESEQQLILELEDLRKQLQQAARELLTLKEEKSVLWNQK------ETLTNEAKEREAGSPVLPAHKDTALQE 281
Cdd:COG4717 204 LQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLllliaaALLALLGLGGSLLSLILTIAGVLFLVL 283
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 282 EV---ESLTRVQWESRKQSEKDRATLLSQMRVLESELEDQLVQHRG--CAQLAEEVATLKQQLAALDKHLRSQRQFMD-- 354
Cdd:COG4717 284 GLlalLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGlpPDLSPEELLELLDRIEELQELLREAEELEEel 363
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 355 DQAAEREHEREEFQQEIQRLEGQLRQAARprppgpRDSQCVQLDEEVELLQEKLREKLDGFNELVIKKDFADqqlliQEE 434
Cdd:COG4717 364 QLEELEQEIAALLAEAGVEDEEELRAALE------QAEEYQELKEELEELEEQLEELLGELEELLEALDEEE-----LEE 432
|
330 340 350
....*....|....*....|....*....|....*..
gi 1039732412 435 EIKRLEETNASIQRQMVQLQEELEKQKKSMEELKEKE 471
Cdd:COG4717 433 ELEELEEELEELEEELEELREELAELEAELEQLEEDG 469
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
396-659 |
1.46e-04 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 46.30 E-value: 1.46e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 396 QLDEEVELLQEKLREKLDGFNELVIKKDFADQQLLIQEEEIKRLEETNASIQRQMVQLQEELEKQKKSMEELkEKEILKQ 475
Cdd:COG4942 24 EAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAEL-RAELEAQ 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 476 ENMGDLLLTTVSRSGLDEAGCPMLPQGSSSRGpeaqpdVTERALLQHeneVVHRRNSEIDELKSLIENLQENQRQLQKDK 555
Cdd:COG4942 103 KEELAELLRALYRLGRQPPLALLLSPEDFLDA------VRRLQYLKY---LAPARREQAEELRADLAELAALRAELEAER 173
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 556 AEeieqlhevIEKLQSELslmgpkvhevsdpqagslhselaclrgeglggQALRSELQAAQAAKEVFGQLLADQAHGHSQ 635
Cdd:COG4942 174 AE--------LEALLAEL--------------------------------EEERAALEALKAERQKLLARLEKELAELAA 213
|
250 260
....*....|....*....|....
gi 1039732412 636 ALEALQQRLQDAEEVAARHLAELE 659
Cdd:COG4942 214 ELAELQQEAEELEALIARLEAEAA 237
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
175-389 |
2.07e-04 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 45.91 E-value: 2.07e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 175 ERLREESAAKDRLALELHTAKGLLEGFKVEKVDLQEALGKKEESEQQLILELEDLRKQLQQAARELLTLKEEKSVLWNQK 254
Cdd:COG4942 20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAEL 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 255 ETLTNEAKER--------EAGSPVLPAHKDTALQEE-----VESLTRVQWESRKQSEKDRATLLSQMRVLESELEDQLVQ 321
Cdd:COG4942 100 EAQKEELAELlralyrlgRQPPLALLLSPEDFLDAVrrlqyLKYLAPARREQAEELRADLAELAALRAELEAERAELEAL 179
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1039732412 322 HRGCAQLAEEVATLKQQLAALDKHLRSQRQFMDDQAAEREHEREEFQQEIQRLEGQLRQAARPRPPGP 389
Cdd:COG4942 180 LAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAG 247
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
154-476 |
2.28e-04 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 46.50 E-value: 2.28e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 154 REFRHRNEEMAQAMQKQQELLERLREesaakdrLALELHTAKGLLEGFKVEKVDLQEALGKKEESEQQLILELEDLRKQL 233
Cdd:pfam02463 166 RLKRKKKEALKKLIEETENLAELIID-------LEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEER 238
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 234 QQAARELLTLKEEKSVLWNQKETLTNEAKEREagspvlpaHKDTALQEEVESLTRVQwesRKQSEKDRATLLSQMRVLES 313
Cdd:pfam02463 239 IDLLQELLRDEQEEIESSKQEIEKEEEKLAQV--------LKENKEEEKEKKLQEEE---LKLLAKEEEELKSELLKLER 307
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 314 ELEDqlvqhrgcaqLAEEVATLKQQLAALDKHLRSQRQFMDDQAAEREHEREEFQQEIQRLEG--QLRQAARPRPPGPRD 391
Cdd:pfam02463 308 RKVD----------DEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEEleKLQEKLEQLEEELLA 377
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 392 SQC---VQLDEEVELLQEKLREKLDGFNELVIKKDFADQQLLIQEEEIKRLEETNASIQRQMVQLQEELEKQKKSMEELK 468
Cdd:pfam02463 378 KKKlesERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQE 457
|
....*...
gi 1039732412 469 EKEILKQE 476
Cdd:pfam02463 458 LKLLKDEL 465
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
122-574 |
2.33e-04 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 46.65 E-value: 2.33e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 122 QSLSTAVEGLLEMALDSSKQLEEARQLHRCVErEFRHRNEEMAQAMQKQQELLERLREESAAK-DRLALELHTAKGLLEG 200
Cdd:pfam15921 110 QSVIDLQTKLQEMQMERDAMADIRRRESQSQE-DLRNQLQNTVHELEAAKCLKEDMLEDSNTQiEQLRKMMLSHEGVLQE 188
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 201 FKVEKVDLQEALGKK-EESEQQLILELEDLRKQLQQAARELLT----LKEEKSVLWNQKETLTNEAKEREagSPVLPAHK 275
Cdd:pfam15921 189 IRSILVDFEEASGKKiYEHDSMSTMHFRSLGSAISKILRELDTeisyLKGRIFPVEDQLEALKSESQNKI--ELLLQQHQ 266
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 276 DTALQ------EEVESLTRVQWESRKQSEkdraTLLSQMRVLESELEDQLVQH-RGCAQLAEEVATLKQQLAALDK---- 344
Cdd:pfam15921 267 DRIEQliseheVEITGLTEKASSARSQAN----SIQSQLEIIQEQARNQNSMYmRQLSDLESTVSQLRSELREAKRmyed 342
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 345 ---HLRSQRQFMDDQAAEREHEREEFQQEIQRLEGQLRQAArprppgprdSQCVQLDEEVELLQEKLREKLDGFNELVIK 421
Cdd:pfam15921 343 kieELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLL---------ADLHKREKELSLEKEQNKRLWDRDTGNSIT 413
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 422 KDFADQQLLIQEEEIKRLE--------ETNASIQRQMVQLQ---EELEKQKKSMEELKE-KEILkqenmgdlllttvsRS 489
Cdd:pfam15921 414 IDHLRRELDDRNMEVQRLEallkamksECQGQMERQMAAIQgknESLEKVSSLTAQLEStKEML--------------RK 479
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 490 GLDEAGCPMLPQGSSSRgpeAQPDVTerALLQHENEVVHRRNSEIDELKSLIEnLQENQRQLQKDKAEEIEQLHEVIEKL 569
Cdd:pfam15921 480 VVEELTAKKMTLESSER---TVSDLT--ASLQEKERAIEATNAEITKLRSRVD-LKLQELQHLKNEGDHLRNVQTECEAL 553
|
....*
gi 1039732412 570 QSELS 574
Cdd:pfam15921 554 KLQMA 558
|
|
| Myosin_tail_1 |
pfam01576 |
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ... |
167-572 |
2.48e-04 |
|
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.
Pssm-ID: 460256 [Multi-domain] Cd Length: 1081 Bit Score: 46.32 E-value: 2.48e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 167 MQKQ-QELLERLREESAAKDRLALElhtakgllegfkveKVDLQEALGKKEESeqqlILELEDLRKQLQQaarelltlke 245
Cdd:pfam01576 101 MQQHiQDLEEQLDEEEAARQKLQLE--------------KVTTEAKIKKLEED----ILLLEDQNSKLSK---------- 152
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 246 EKSVLWNQKETLTNEAKEREAGSPVLpahkdTALQEEVESLTRVQWESRKQSEKDRATLLSQMRVLESELEDQLVQHrgc 325
Cdd:pfam01576 153 ERKLLEERISEFTSNLAEEEEKAKSL-----SKLKNKHEAMISDLEERLKKEEKGRQELEKAKRKLEGESTDLQEQI--- 224
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 326 AQLAEEVATLKQQLAALDKHLRSQRQFMDDQAAEREHEreefQQEIQRLEGQL---------RQAARPRPpgprDSQCVQ 396
Cdd:pfam01576 225 AELQAQIAELRAQLAKKEEELQAALARLEEETAQKNNA----LKKIRELEAQIselqedlesERAARNKA----EKQRRD 296
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 397 LDEEVELLQEKLREKLDGFN---ELVIKKDFADQQLLIQEEEIKRLEETNASIQRQ-----MVQLQEELEKQKKSMEEL- 467
Cdd:pfam01576 297 LGEELEALKTELEDTLDTTAaqqELRSKREQEVTELKKALEEETRSHEAQLQEMRQkhtqaLEELTEQLEQAKRNKANLe 376
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 468 KEKEILKQEN--MGDLLLTTVSRSGLDEAGCPMLP---QGSSSRGPEAQPDVTERAllqhenEVVHRRNSEIDELKSLIE 542
Cdd:pfam01576 377 KAKQALESENaeLQAELRTLQQAKQDSEHKRKKLEgqlQELQARLSESERQRAELA------EKLSKLQSELESVSSLLN 450
|
410 420 430
....*....|....*....|....*....|
gi 1039732412 543 NLQENQRQLQKDKAEEIEQLHEVIEKLQSE 572
Cdd:pfam01576 451 EAEGKNIKLSKDVSSLESQLQDTQELLQEE 480
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
226-456 |
3.80e-04 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 45.68 E-value: 3.80e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 226 LEDLRKQLQQAARELLTLKEEKSVLWNQKETLtneakereagspvlpahkdTALQEEVESLTRVQWEsrkqsEKDRATLL 305
Cdd:COG4913 612 LAALEAELAELEEELAEAEERLEALEAELDAL-------------------QERREALQRLAEYSWD-----EIDVASAE 667
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 306 SQMRVLESELEDQLVQHRGCAQLAEEVATLKQQLAALDKHLRSQRQfmddqaaerehEREEFQQEIQRLEGQLRQAARpr 385
Cdd:COG4913 668 REIAELEAELERLDASSDDLAALEEQLEELEAELEELEEELDELKG-----------EIGRLEKELEQAEEELDELQD-- 734
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1039732412 386 ppgprdsqcvQLDEEVELLQEKLREKLDGFNELVIKKDFADQQLLIQEEEIKRLEETNASIQRQMVQLQEE 456
Cdd:COG4913 735 ----------RLEAAEDLARLELRALLEERFAAALGDAVERELRENLEERIDALRARLNRAEEELERAMRA 795
|
|
| COG2433 |
COG2433 |
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only]; |
1547-1702 |
4.68e-04 |
|
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
Pssm-ID: 441980 [Multi-domain] Cd Length: 644 Bit Score: 45.23 E-value: 4.68e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 1547 KLKAEKTRALELEAMLEKVQKQAAHTQQQLEAQAQERCV-ELRREKEVSGNLRSAVDALRTHKQELgcclqrerekaawl 1625
Cdd:COG2433 367 EVKARVIRGLSIEEALEELIEKELPEEEPEAEREKEHEErELTEEEEEIRRLEEQVERLEAEVEEL-------------- 432
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 1626 QAELEQLSARVKEQEAR-KDARRMERRSSRADldkRKWQRDKETLRELEIQRQRDEHKIEQLQRLVRELR--WKEEVSGG 1702
Cdd:COG2433 433 EAELEEKDERIERLERElSEARSEERREIRKD---REISRLDREIERLERELEEERERIEELKRKLERLKelWKLEHSGE 509
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
121-573 |
5.39e-04 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 45.05 E-value: 5.39e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 121 YQSLSTAVEGLLEMALDSSKQLEEARQLHRCVEREF-----RHRNEEMAQAMQKQ-------------QELLERLREESA 182
Cdd:PRK03918 319 LEEEINGIEERIKELEEKEERLEELKKKLKELEKRLeeleeRHELYEEAKAKKEElerlkkrltgltpEKLEKELEELEK 398
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 183 AKDRLALELHTAKGLLEGFKVEKVDLQEALGKKEESEQQLIL---EL-EDLRKQL-QQAARELLTLKEEKSVLWNQKETL 257
Cdd:PRK03918 399 AKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCPVcgrELtEEHRKELlEEYTAELKRIEKELKEIEEKERKL 478
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 258 TNEAKERE---AGSPVLPAHKDTA--LQEEVESLTRVQWESRKQSEKDRATLLSQMRVLESELedqlvqhRGCAQLAEEV 332
Cdd:PRK03918 479 RKELRELEkvlKKESELIKLKELAeqLKELEEKLKKYNLEELEKKAEEYEKLKEKLIKLKGEI-------KSLKKELEKL 551
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 333 ATLKQQLAALDKHLRSqrqfmddqaaerehereeFQQEIQRLEGQLRQAARprppgprdsqcvqldEEVELLQEKLREKL 412
Cdd:PRK03918 552 EELKKKLAELEKKLDE------------------LEEELAELLKELEELGF---------------ESVEELEERLKELE 598
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 413 DGFNELVIKKDfADQQLLIQEEEIKRLEETNASIQRQMVQLQEELEKQKKSMEELKEK-EILKQENMGDLLLTTVSR-SG 490
Cdd:PRK03918 599 PFYNEYLELKD-AEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKySEEEYEELREEYLELSRElAG 677
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 491 LDEagcpmlpqgsSSRGPEAQPDVTERAL--LQHENEVVHRRNSEIDELKSLIENLQENQRQLQKDKAEEIEQLHEVIEK 568
Cdd:PRK03918 678 LRA----------ELEELEKRREEIKKTLekLKEELEEREKAKKELEKLEKALERVEELREKVKKYKALLKERALSKVGE 747
|
....*
gi 1039732412 569 LQSEL 573
Cdd:PRK03918 748 IASEI 752
|
|
| HEC1 |
COG5185 |
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell ... |
209-482 |
5.63e-04 |
|
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 444066 [Multi-domain] Cd Length: 594 Bit Score: 44.95 E-value: 5.63e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 209 QEALGKKEESEQQLILELEDLRKQLQQAaRELLTLKEEKSVLWNQKETLTNEAKEREAGSPVlpahkdTALQEEVESLTR 288
Cdd:COG5185 267 LEKLGENAESSKRLNENANNLIKQFENT-KEKIAEYTKSIDIKKATESLEEQLAAAEAEQEL------EESKRETETGIQ 339
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 289 VQWEsrkQSEKDRATLLSQMRVLESELEdQLVQHRGCAQLAEEVATLKQQLAALDKHL----RSQRQFMDDQAAEREHER 364
Cdd:COG5185 340 NLTA---EIEQGQESLTENLEAIKEEIE-NIVGEVELSKSSEELDSFKDTIESTKESLdeipQNQRGYAQEILATLEDTL 415
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 365 EEFQQEIQRLEGQLRQAARprppgprdsqcvqldeEVELLQEKLREKLDGFNELVIKKDFADQQLLIQE--EEIKRLEET 442
Cdd:COG5185 416 KAADRQIEELQRQIEQATS----------------SNEEVSKLLNELISELNKVMREADEESQSRLEEAydEINRSVRSK 479
|
250 260 270 280
....*....|....*....|....*....|....*....|
gi 1039732412 443 NASIQRQMVQLQEELEKQKKSMEELKEKEILKQENMGDLL 482
Cdd:COG5185 480 KEDLNEELTQIESRVSTLKATLEKLRAKLERQLEGVRSKL 519
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
1294-1633 |
6.21e-04 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 45.05 E-value: 6.21e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 1294 HQLRRQVELL---AYKVEQEKCIANEL---QKTLSKeqetasdvrKRLVVEQNAVQDLKSELHACKQENTSLLESLDKVQ 1367
Cdd:TIGR02168 196 NELERQLKSLerqAEKAERYKELKAELrelELALLV---------LRLEELREELEELQEELKEAEEELEELTAELQELE 266
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 1368 QEVLRLRYGHvtwsycgtSSASAGRAVLDGKEKELKVVLEELESERGKGQALQAQQEEQQLRY---LQREGQSSRALEEL 1444
Cdd:TIGR02168 267 EKLEELRLEV--------SELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELeaqLEELESKLDELAEE 338
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 1445 KLSLEKQLAQNNQLCVALKHERAAKDNLQKELQIEASRCEALLAQEKGQLSELQKSLEAERSRSLELSEALqherlltEQ 1524
Cdd:TIGR02168 339 LAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARL-------ER 411
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 1525 LSRNSQEACARQETQVQHALLRKLKAEKTRALELEAMLEKVQKQAAHTQqqleaqaqercvelRREKEVSGNLRSAVDAL 1604
Cdd:TIGR02168 412 LEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLE--------------EALEELREELEEAEQAL 477
|
330 340
....*....|....*....|....*....
gi 1039732412 1605 RTHKQElgccLQREREKAAWLQAELEQLS 1633
Cdd:TIGR02168 478 DAAERE----LAQLQARLDSLERLQENLE 502
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
1278-1535 |
6.84e-04 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 44.37 E-value: 6.84e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 1278 LCAALTSTEARGSQREHQL---RRQVELLAYKVEQEKCIANELQKTLSKEQETASDVRKRLVVEQNAVQDLKSELHACKQ 1354
Cdd:COG4942 11 LALAAAAQADAAAEAEAELeqlQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEK 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 1355 ENTSLLESLDKVQQEVLRLryghvtwsycgtssasAGRAVLDGKEKELKVVLeelesergkgqalQAQQEEQQLRYLQRE 1434
Cdd:COG4942 91 EIAELRAELEAQKEELAEL----------------LRALYRLGRQPPLALLL-------------SPEDFLDAVRRLQYL 141
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 1435 GQSSRALEELKLSLEKQLAQNNQLCVALKHERAAKDNLQKELQIEASRCEALLAQEKGQLSELQKSLEAERSRSLELSEA 1514
Cdd:COG4942 142 KYLAPARREQAEELRADLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQE 221
|
250 260
....*....|....*....|.
gi 1039732412 1515 LQHERLLTEQLSRNSQEACAR 1535
Cdd:COG4942 222 AEELEALIARLEAEAAAAAER 242
|
|
| PRK09039 |
PRK09039 |
peptidoglycan -binding protein; |
562-698 |
7.45e-04 |
|
peptidoglycan -binding protein;
Pssm-ID: 181619 [Multi-domain] Cd Length: 343 Bit Score: 44.19 E-value: 7.45e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 562 LHEVIEKLQSELSLMGPKVHEVSD------PQAGSLHSELACLRGEGLGGQALRSELQAAQAAKEVFGQLLADQAHGHSQ 635
Cdd:PRK09039 44 LSREISGKDSALDRLNSQIAELADllslerQGNQDLQDSVANLRASLSAAEAERSRLQALLAELAGAGAAAEGRAGELAQ 123
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1039732412 636 ALEALQQrlqdaeeVAARHLAElehcVALREAEVEAMASQIQEFAATLKAKEAIIEQRDLEID 698
Cdd:PRK09039 124 ELDSEKQ-------VSARALAQ----VELLNQQIAALRRQLAALEAALDASEKRDRESQAKIA 175
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
1224-1692 |
8.62e-04 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 44.37 E-value: 8.62e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 1224 LVQRLEKVIQEQGDPQKVQDHLCLSDRSSLLAEIQALRAQLRmTHLQNQEKLQQLCAALTSTEARGSQREHQLRR-QVEL 1302
Cdd:COG4717 47 LLERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEE-EYAELQEELEELEEELEELEAELEELREELEKlEKLL 125
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 1303 LAYKVEQEKCIANELQKTLSKEQETASDVRKRLVVEQNAVQDLKSELHACKQENTSLLESLD-KVQQEVLRLRYGHvtws 1381
Cdd:COG4717 126 QLLPLYQELEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSlATEEELQDLAEEL---- 201
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 1382 ycgtSSASAGRAVLDGKEKELKVVLEELESERGKGQALQAQQEEQQLRYLQREGQSSRALEELKLSLEKQLAQNNQ---- 1457
Cdd:COG4717 202 ----EELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILtiag 277
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 1458 ---------LCVALKHERAAKDNLQKELQIEASRCEALLAQE--KGQLSELQKSLEAERSRSLELSEALQHERLLTEQLS 1526
Cdd:COG4717 278 vlflvlgllALLFLLLAREKASLGKEAEELQALPALEELEEEelEELLAALGLPPDLSPEELLELLDRIEELQELLREAE 357
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 1527 RNSQEACARQETQVQHALLRKLKAEKtralelEAMLEKVQKQAAhtqqqleaqaqeRCVELRREkevsgnLRSAVDALRT 1606
Cdd:COG4717 358 ELEEELQLEELEQEIAALLAEAGVED------EEELRAALEQAE------------EYQELKEE------LEELEEQLEE 413
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 1607 HKQELGCCLQREREKAawLQAELEQLSARVKEQEARKDARRMERRSSRADLdkrkwqRDKETLRELEIQRQRDEHKIEQL 1686
Cdd:COG4717 414 LLGELEELLEALDEEE--LEEELEELEEELEELEEELEELREELAELEAEL------EQLEEDGELAELLQELEELKAEL 485
|
....*.
gi 1039732412 1687 QRLVRE 1692
Cdd:COG4717 486 RELAEE 491
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
153-469 |
8.88e-04 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 44.44 E-value: 8.88e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 153 EREFRHRNEEMAQAMQKQQELLERLREEsaakdrlaleLHTAKGLLEGFKVEKVDLQEALGKKEESEQQLILELEDLRKQ 232
Cdd:pfam12128 599 EEELRERLDKAEEALQSAREKQAAAEEQ----------LVQANGELEKASREETFARTALKNARLDLRRLFDEKQSEKDK 668
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 233 LQQAarelltLKEEKSVLWNQKETLTNEAKEREAGspvlpaHKDtALQEEvesltrvqwesRKQSEKDRATLLSQMRVLE 312
Cdd:pfam12128 669 KNKA------LAERKDSANERLNSLEAQLKQLDKK------HQA-WLEEQ-----------KEQKREARTEKQAYWQVVE 724
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 313 SELEDQLvqhrgcAQLAEEVATLKQQLAALDKHLRSQRQFMDDQAAEREHEREEFQQEIQRLEGQLRQAARPRPPGPR-- 390
Cdd:pfam12128 725 GALDAQL------ALLKAAIAARRSGAKAELKALETWYKRDLASLGVDPDVIAKLKREIRTLERKIERIAVRRQEVLRyf 798
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 391 DSQCVQLDEEVELLQEKLREKLDGFNELvikkdfaDQQLLIQEEEIKR----LEETNASIQRQMVQLQEELEKQKKSMEE 466
Cdd:pfam12128 799 DWYQETWLQRRPRLATQLSNIERAISEL-------QQQLARLIADTKLrrakLEMERKASEKQQVRLSENLRGLRCEMSK 871
|
...
gi 1039732412 467 LKE 469
Cdd:pfam12128 872 LAT 874
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
1166-1698 |
9.54e-04 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 44.28 E-value: 9.54e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 1166 SQALSEVTTDKGE-KESLETHLTWSEELLRAIQEVFAR----EQEKAELQPRpYGSNLGDYNSLVQRLEKVIQEQGD--- 1237
Cdd:TIGR02168 294 ANEISRLEQQKQIlRERLANLERQLEELEAQLEELESKldelAEELAELEEK-LEELKEELESLEAELEELEAELEEles 372
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 1238 -PQKVQDHL--CLSDRSSLLAEIQALRAQLRmthlQNQEKLQQLCAALTSTEARGSQREHQLRR-QVELLAYKVEQEKCI 1313
Cdd:TIGR02168 373 rLEELEEQLetLRSKVAQLELQIASLNNEIE----RLEARLERLEDRRERLQQEIEELLKKLEEaELKELQAELEELEEE 448
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 1314 ANELQKTLSKEQETASDVRKRLVVEQNAVQDLKSELHACKQEntslLESLDKVQQEVLRLRYGHVTW------------- 1380
Cdd:TIGR02168 449 LEELQEELERLEEALEELREELEEAEQALDAAERELAQLQAR----LDSLERLQENLEGFSEGVKALlknqsglsgilgv 524
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 1381 ------------------------SYCGTSSASAGRAVLDGKEKEL-KVVLEELESERGKGQALQAQQEEQQLRYLQREG 1435
Cdd:TIGR02168 525 lselisvdegyeaaieaalggrlqAVVVENLNAAKKAIAFLKQNELgRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVA 604
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 1436 QSsraLEELKLSLEK-------------QLAQNNQLCVALKHE--------------------RAAKDNLQKELQIEASR 1482
Cdd:TIGR02168 605 KD---LVKFDPKLRKalsyllggvlvvdDLDNALELAKKLRPGyrivtldgdlvrpggvitggSAKTNSSILERRREIEE 681
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 1483 CEALLAQEKGQLSELQKSLEAERSRSLELSEALQHERLLTEQLSR-------------NSQEACARQETQVQHALLRkLK 1549
Cdd:TIGR02168 682 LEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRqisalrkdlarleAEVEQLEERIAQLSKELTE-LE 760
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 1550 AEKTRALELEAMLEKVQKQAAHTQQQLEAQAQERCVELRREKEVSGNLRSAVDALRTHKQELGCCLQREREKAAWLQAEL 1629
Cdd:TIGR02168 761 AEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRL 840
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1039732412 1630 EQLSARVKEQEARKDARRMERRSSRADLDKRKWQRDKETLRELEIQRQRDEHKiEQLQRLVRELRWKEE 1698
Cdd:TIGR02168 841 EDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLR-SELEELSEELRELES 908
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
134-696 |
1.18e-03 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 44.29 E-value: 1.18e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 134 MALDSSKQLEEARQLHRcVEREFRHRNEEMAQAMQKQQELLERLREESAAKDRLALELHTAKGLLEGFKVEKVDLQEALG 213
Cdd:TIGR02169 282 KDLGEEEQLRVKEKIGE-LEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYA 360
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 214 KKEESEQQLILELE--------------DLRKQLQQAARELLTLKEEKSVLWNQKETLTNEAKEREAGSPVLPAhKDTAL 279
Cdd:TIGR02169 361 ELKEELEDLRAELEevdkefaetrdelkDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEA-KINEL 439
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 280 QEEVESLTRVQWESR---KQSEKDRATLLSQMRVLESELEdqlvqhrgcaQLAEEVATLKQQLAALDKhlrsQRQFMDDQ 356
Cdd:TIGR02169 440 EEEKEDKALEIKKQEwklEQLAADLSKYEQELYDLKEEYD----------RVEKELSKLQRELAEAEA----QARASEER 505
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 357 AAEREHEREEFQQEIQRLEGQLRQAARPRP---------PGPRDSQCVQLDEEV-----ELLQE------------KLRE 410
Cdd:TIGR02169 506 VRGGRAVEEVLKASIQGVHGTVAQLGSVGEryataievaAGNRLNNVVVEDDAVakeaiELLKRrkagratflplnKMRD 585
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 411 K--------LDGFN-------------ELVIKKDFADQQLLIQEEEIKRLeetnaSIQRQMVQLQEELEKQKKSM----- 464
Cdd:TIGR02169 586 ErrdlsilsEDGVIgfavdlvefdpkyEPAFKYVFGDTLVVEDIEAARRL-----MGKYRMVTLEGELFEKSGAMtggsr 660
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 465 ---------EELKEKEILKQENMGDL------LLTTVSR--SGLDEAgcpmlpqgsSSRGPEAQPDVTERALLQHENEVV 527
Cdd:TIGR02169 661 aprggilfsRSEPAELQRLRERLEGLkrelssLQSELRRieNRLDEL---------SQELSDASRKIGEIEKEIEQLEQE 731
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 528 HRRNSE-IDELKSLIENLQ---ENQRQLQKDKAEEIEQLHEVIEKLQSELslmgpkvhevSDPQAGSLHSELACLRGEGL 603
Cdd:TIGR02169 732 EEKLKErLEELEEDLSSLEqeiENVKSELKELEARIEELEEDLHKLEEAL----------NDLEARLSHSRIPEIQAELS 801
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 604 GGQALRSELQAAqaakevfgqllADQAHGHSQALEALQQRLQDAEEVAARHLAELEHCVALREAEVEAMASQIQEFAATL 683
Cdd:TIGR02169 802 KLEEEVSRIEAR-----------LREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEEL 870
|
650
....*....|...
gi 1039732412 684 KAKEAiiEQRDLE 696
Cdd:TIGR02169 871 EELEA--ALRDLE 881
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
131-619 |
1.22e-03 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 43.94 E-value: 1.22e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 131 LLEMALDSSKQLEEARQLHrcvEREFRHRNEEMAQAMQKQQELLERLREESAAKDRLALELHTAKGLLEGFKVEKVDLQE 210
Cdd:pfam05483 262 LLEESRDKANQLEEKTKLQ---DENLKELIEKKDHLTKELEDIKMSLQRSMSTQKALEEDLQIATKTICQLTEEKEAQME 338
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 211 ALGKKEESEQQLILELEDLRKQLQQaarellTLKEEKSVLWNQKETLTNEAKEREAGSpvlpahkdtalqEEVESLTRVQ 290
Cdd:pfam05483 339 ELNKAKAAHSFVVTEFEATTCSLEE------LLRTEQQRLEKNEDQLKIITMELQKKS------------SELEEMTKFK 400
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 291 wesrkqseKDRATLLSQMRVLESELEDQLVQHRGCAQLAEEVATLKQQLAALDKHLRSQRQFMDDQAAEREHEREEFQQE 370
Cdd:pfam05483 401 --------NNKEVELEELKKILAEDEKLLDEKKQFEKIAEELKGKEQELIFLLQAREKEIHDLEIQLTAIKTSEEHYLKE 472
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 371 IQRLEGQLRQAARPRPPGPRDSQCVQLdEEVELLQE--KLREKLDGFNELVIKKDFADQQLLIQeeeIKRLEETNASIQR 448
Cdd:pfam05483 473 VEDLKTELEKEKLKNIELTAHCDKLLL-ENKELTQEasDMTLELKKHQEDIINCKKQEERMLKQ---IENLEEKEMNLRD 548
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 449 QMVQLQEELEKQKksmeelkekeilkqenmgdlllttvsrsglDEAGCPMLPQGSSSRGPEAQPDVTERALLQHENEVVH 528
Cdd:pfam05483 549 ELESVREEFIQKG------------------------------DEVKCKLDKSEENARSIEYEVLKKEKQMKILENKCNN 598
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 529 RRnSEIDELKSLIENLQENQRQLQKDKAEEIEQL--HEV-IEKLQSELSLMGPKVHEVSDPQAGSLhsELACLRGEGLGG 605
Cdd:pfam05483 599 LK-KQIENKNKNIEELHQENKALKKKGSAENKQLnaYEIkVNKLELELASAKQKFEEIIDNYQKEI--EDKKISEEKLLE 675
|
490
....*....|....
gi 1039732412 606 QALRSELQAAQAAK 619
Cdd:pfam05483 676 EVEKAKAIADEAVK 689
|
|
| Cast |
pfam10174 |
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ... |
193-473 |
1.28e-03 |
|
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.
Pssm-ID: 431111 [Multi-domain] Cd Length: 766 Bit Score: 44.04 E-value: 1.28e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 193 TAKGLLEGFKVEKVDLQEALGK-KEESEQQLILELEDLRKQLQQAARELLTLKEEKSvlwnQKETLTNEAKEREAGSPVL 271
Cdd:pfam10174 436 TALTTLEEALSEKERIIERLKEqREREDRERLEELESLKKENKDLKEKVSALQPELT----EKESSLIDLKEHASSLASS 511
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 272 PAHKDT-------ALQEEVESLTRVQWESRK-----QSEKDRATLLSQMRVLESELEDQLVQHRGC-AQLAEEVATLKQq 338
Cdd:pfam10174 512 GLKKDSklksleiAVEQKKEECSKLENQLKKahnaeEAVRTNPEINDRIRLLEQEVARYKEESGKAqAEVERLLGILRE- 590
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 339 lAALDKHLRSQR---------QFMDDQAAEREHEREEFQQEIQRLEGQLRQAARPRPPGPRDSQCVQLDEEVELLqEKLR 409
Cdd:pfam10174 591 -VENEKNDKDKKiaelesltlRQMKEQNKKVANIKHGQQEMKKKGAQLLEEARRREDNLADNSQQLQLEELMGAL-EKTR 668
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1039732412 410 EKLDgfnelVIKKDFADQQLLIQEEEikrleetnasiqRQMVQLQEELEKQKKSMEELKEKEIL 473
Cdd:pfam10174 669 QELD-----ATKARLSSTQQSLAEKD------------GHLTNLRAERRKQLEEILEMKQEALL 715
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
1248-1569 |
1.95e-03 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 43.52 E-value: 1.95e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 1248 SDRSSLLAEIQALRAQLrmthlqnqEKLQQLCAALTSTEARGSQREHQLRRQVELLAYKVEQEKCIANELQKTLSKEQET 1327
Cdd:TIGR02169 667 LFSRSEPAELQRLRERL--------EGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKER 738
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 1328 ASDVRKRLVVEQNAVQDLKSELHACKQENTSLLESLDKVQQEV--LRLRYGHVTWSYCGT---------SSASAGRAVLD 1396
Cdd:TIGR02169 739 LEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALndLEARLSHSRIPEIQAelskleeevSRIEARLREIE 818
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 1397 GKEKELKVVLEELESERGKGQALQAQQEEQQLRYLQREGQSSRALEELKLSLEKQLAQNNQLCVALKHERAAKDNLQK-- 1474
Cdd:TIGR02169 819 QKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAql 898
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 1475 --------ELQIEASRCEALLAQEKGQLSELQ---KSLEAERSRSLELSEALQHERLLTEQLSRNSQEACA------RQE 1537
Cdd:TIGR02169 899 relerkieELEAQIEKKRKRLSELKAKLEALEeelSEIEDPKGEDEEIPEEELSLEDVQAELQRVEEEIRAlepvnmLAI 978
|
330 340 350 360
....*....|....*....|....*....|....*....|.
gi 1039732412 1538 TQVQHALLR---------KLKAEKTRALELEAMLEKVQKQA 1569
Cdd:TIGR02169 979 QEYEEVLKRldelkekraKLEEERKAILERIEEYEKKKREV 1019
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
279-578 |
2.07e-03 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 43.52 E-value: 2.07e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 279 LQEEVESLTRVqwESRKQSEKDRA-TLLSQMRVLESELEDQLVQ-HRGCAQLAEEVATLKQQLAALdkhlRSQRQFMDDQ 356
Cdd:TIGR02169 679 LRERLEGLKRE--LSSLQSELRRIeNRLDELSQELSDASRKIGEiEKEIEQLEQEEEKLKERLEEL----EEDLSSLEQE 752
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 357 AAEREHEREEFQQEIQRLE---GQLRQAARPRPPGPRDSQCVQLDEEVELLQEKLREKLDGFNELVIKKDFADQQLLIQE 433
Cdd:TIGR02169 753 IENVKSELKELEARIEELEedlHKLEEALNDLEARLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLE 832
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 434 EEIKRLEETNASIQRQMVQLQEELEKQKKSMEELKEKEILKQENMGDLlltTVSRSGLDEagcpmlpqgsSSRGPEAQPD 513
Cdd:TIGR02169 833 KEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDL---ESRLGDLKK----------ERDELEAQLR 899
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1039732412 514 VTERAlLQHENEVVHRRNSEIDELKSLIENLQENQRQLQKDKAEE---------IEQLHEVIEKLQSELSLMGP 578
Cdd:TIGR02169 900 ELERK-IEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDeeipeeelsLEDVQAELQRVEEEIRALEP 972
|
|
| MukB |
COG3096 |
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ... |
115-463 |
2.36e-03 |
|
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 43.40 E-value: 2.36e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 115 QPIRRVYQSLSTAVEGLLEMALDSS--KQLEEARQLHRCVEREFrhrnEEMAQAMQKQQELLERLREESAAKDRLALELH 192
Cdd:COG3096 809 QKLQRLHQAFSQFVGGHLAVAFAPDpeAELAALRQRRSELEREL----AQHRAQEQQLRQQLDQLKEQLQLLNKLLPQAN 884
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 193 TakgLLEGFKVEKVD-LQEALGKKEESEQQL------ILELEDLRKQLQ-------QAARELLTLKEEKSVLWNQKETLT 258
Cdd:COG3096 885 L---LADETLADRLEeLREELDAAQEAQAFIqqhgkaLAQLEPLVAVLQsdpeqfeQLQADYLQAKEQQRRLKQQIFALS 961
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 259 NEAKEREAgspvlpahkdTALQEEVESLTrvqwESRKQSEKDRAtllsQMRVLESELEDQLVQHRgcaQLAEEVATLKQQ 338
Cdd:COG3096 962 EVVQRRPH----------FSYEDAVGLLG----ENSDLNEKLRA----RLEQAEEARREAREQLR---QAQAQYSQYNQV 1020
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 339 LAALDKHLRSQRQFMDDqaaerehereeFQQEIQRLEgqlrqaarprppgprdsqcVQLDEEVEllqEKLREKLDGFNEL 418
Cdd:COG3096 1021 LASLKSSRDAKQQTLQE-----------LEQELEELG-------------------VQADAEAE---ERARIRRDELHEE 1067
|
330 340 350 360
....*....|....*....|....*....|....*....|....*....
gi 1039732412 419 VI----KKDFADQQLLIQEEEIKRLEETNASIQRQMVQLQEELEKQKKS 463
Cdd:COG3096 1068 LSqnrsRRSQLEKQLTRCEAEMDSLQKRLRKAERDYKQEREQVVQAKAG 1116
|
|
| UPF0242 |
pfam06785 |
Uncharacterized protein family (UPF0242) N-terminus; This region includes an N-terminal ... |
402-476 |
2.95e-03 |
|
Uncharacterized protein family (UPF0242) N-terminus; This region includes an N-terminal transmembrane region and a C-terminal coiled-coil.
Pssm-ID: 429117 [Multi-domain] Cd Length: 194 Bit Score: 40.96 E-value: 2.95e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1039732412 402 ELLQEKLREKLDGFNELVIKKDFADQQLLIQEEEIKRLEETNASIQRQMVQLQEELEKQKKSMEE-LKEKEILKQE 476
Cdd:pfam06785 79 ELDAEGFKILEETLEELQSEEERLEEELSQKEEELRRLTEENQQLQIQLQQISQDFAEFRLESEEqLAEKQLLINE 154
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
1433-1687 |
3.10e-03 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 42.75 E-value: 3.10e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 1433 REGQSSRALEELKLSLEKQLAQNNQLCVALKHERAAKDNLQKELQI---EASRCEALLAQEKGQLSELQKSLEAERSRSL 1509
Cdd:TIGR02169 682 RLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQleqEEEKLKERLEELEEDLSSLEQEIENVKSELK 761
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 1510 ELSEALQ--HERLLTEQLSRNSQEA-CARQETQVQHALLRKLKAEKTRaleLEAMLEKVQK--QAAHTQQQLEAQAQERC 1584
Cdd:TIGR02169 762 ELEARIEelEEDLHKLEEALNDLEArLSHSRIPEIQAELSKLEEEVSR---IEARLREIEQklNRLTLEKEYLEKEIQEL 838
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 1585 VELRRE-KEVSGNLRSAVDALRTHKQELgcclqrerekaawlQAELEQLSARVKEQEARKDARRMERRSSRADLdkRKWQ 1663
Cdd:TIGR02169 839 QEQRIDlKEQIKSIEKEIENLNGKKEEL--------------EEELEELEAALRDLESRLGDLKKERDELEAQL--RELE 902
|
250 260
....*....|....*....|....
gi 1039732412 1664 RDKEtlrELEIQRQRDEHKIEQLQ 1687
Cdd:TIGR02169 903 RKIE---ELEAQIEKKRKRLSELK 923
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
122-247 |
3.35e-03 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 42.74 E-value: 3.35e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 122 QSLSTAVEGLLEMALDSSKQLEEARQLHRCVEREFRHRNEEMAQAMQKQQELLERLREESAAKDRLALELHTAKGLLEGF 201
Cdd:TIGR02168 855 ESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGL 934
|
90 100 110 120
....*....|....*....|....*....|....*....|....*.
gi 1039732412 202 KVEKVDLQEALGKKEESEQQLILELEDLRKQLQQAARELLTLKEEK 247
Cdd:TIGR02168 935 EVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENK 980
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
1218-1694 |
3.39e-03 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 42.80 E-value: 3.39e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 1218 LGDYNSLVQRLEKVIqeqgdpqKVQDHLCLSDRSSLLAEIQALRAQLrmthlqnqEKLQQLCAALTSTEargsqreHQLR 1297
Cdd:pfam15921 421 LDDRNMEVQRLEALL-------KAMKSECQGQMERQMAAIQGKNESL--------EKVSSLTAQLESTK-------EMLR 478
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 1298 RQVELLAYKveqekcianelQKTLSKEQETASDVRKRLVVEQNAVQDLKSELHACKQENTSLLESLDKVQQEVLRLRYGH 1377
Cdd:pfam15921 479 KVVEELTAK-----------KMTLESSERTVSDLTASLQEKERAIEATNAEITKLRSRVDLKLQELQHLKNEGDHLRNVQ 547
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 1378 vtwsycgtSSASAGRAVLDGKEKELKVVLEELESergkgqalqaqqeeqQLRYLQREGQSSRALEELKLSLEKQLAQNNQ 1457
Cdd:pfam15921 548 --------TECEALKLQMAEKDKVIEILRQQIEN---------------MTQLVGQHGRTAGAMQVEKAQLEKEINDRRL 604
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 1458 LCVALKHERAAKDNLQKELQIEASRCE---ALLAQEKGQLSELQKSLEAERSRSL-ELSEALQHERLLTEQ---LSRNSQ 1530
Cdd:pfam15921 605 ELQEFKILKDKKDAKIRELEARVSDLElekVKLVNAGSERLRAVKDIKQERDQLLnEVKTSRNELNSLSEDyevLKRNFR 684
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 1531 EACARQETqVQHALLRKLKAEKTRALELEAMLEKVQKQAAHTQQqleaqaqercVELRREKEVSGNlRSAVDALRTHKQE 1610
Cdd:pfam15921 685 NKSEEMET-TTNKLKMQLKSAQSELEQTRNTLKSMEGSDGHAMK----------VAMGMQKQITAK-RGQIDALQSKIQF 752
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 1611 LGCCLQREREKAAWLQAELEQLSARVKEQEARK-------DARRMERRSSRADLDKRKWQRDKETLRELE----IQRQRD 1679
Cdd:pfam15921 753 LEEAMTNANKEKHFLKEEKNKLSQELSTVATEKnkmagelEVLRSQERRLKEKVANMEVALDKASLQFAEcqdiIQRQEQ 832
|
490
....*....|....*..
gi 1039732412 1680 EHKIEQLQRL--VRELR 1694
Cdd:pfam15921 833 ESVRLKLQHTldVKELQ 849
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
1456-1677 |
3.45e-03 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 42.42 E-value: 3.45e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 1456 NQLCVALKHERAAKDNLQKElQIEASRCEALLAQEKGQLSELQ---KSLEAERSRSLELSEAL----QHERLLTE---QL 1525
Cdd:pfam17380 272 NQLLHIVQHQKAVSERQQQE-KFEKMEQERLRQEKEEKAREVErrrKLEEAEKARQAEMDRQAaiyaEQERMAMErerEL 350
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 1526 SRNSQEACARQETQVQHallRKLKAEKTRALELEAMLEKVQKQAAHTQQQLEAQAQERCVELRREKEVSGNLRSAV---- 1601
Cdd:pfam17380 351 ERIRQEERKRELERIRQ---EEIAMEISRMRELERLQMERQQKNERVRQELEAARKVKILEEERQRKIQQQKVEMEqira 427
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1039732412 1602 ---DALRTHKQELGCCLQREREKAAWLQAELEQLSARVKEQEARKDARRMERRSSRADLDKRKWQRDKETLRELEIQRQ 1677
Cdd:pfam17380 428 eqeEARQREVRRLEEERAREMERVRLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRRKILEKELEERKQ 506
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
1475-1702 |
3.67e-03 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 42.36 E-value: 3.67e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 1475 ELQIEASRCE---ALLAQEKGQLSELQKSLEAERSRSL----ELSEALQHERLLTEQLSRNSQEACARQETqvqhaLLRK 1547
Cdd:TIGR02169 298 ELEAEIASLErsiAEKERELEDAEERLAKLEAEIDKLLaeieELEREIEEERKRRDKLTEEYAELKEELED-----LRAE 372
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 1548 LKAEKTRALELEAMLEKVQKqaahtqqqleaqaqeRCVELRREK-EVSGNLRSAVDALRTHKQELG---CCLQREREKAA 1623
Cdd:TIGR02169 373 LEEVDKEFAETRDELKDYRE---------------KLEKLKREInELKRELDRLQEELQRLSEELAdlnAAIAGIEAKIN 437
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 1624 WLQAELEQLSARVKEQEArkdarrmERRSSRADLDK--RKWQRDKETLRELEIQRQRDEHKIEQLQRLVRElrWKEEVSG 1701
Cdd:TIGR02169 438 ELEEEKEDKALEIKKQEW-------KLEQLAADLSKyeQELYDLKEEYDRVEKELSKLQRELAEAEAQARA--SEERVRG 508
|
.
gi 1039732412 1702 G 1702
Cdd:TIGR02169 509 G 509
|
|
| MukB |
COG3096 |
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ... |
130-471 |
3.81e-03 |
|
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442330 [Multi-domain] Cd Length: 1470 Bit Score: 42.63 E-value: 3.81e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 130 GLLEMALDSSKQLEEARQLhrcvEREFRHRNEEMAQAMQKQQELLERLREE-SAAKDRLALeLHTAKGLLEgfKVEK--- 205
Cdd:COG3096 282 ELSERALELRRELFGARRQ----LAEEQYRLVEMARELEELSARESDLEQDyQAASDHLNL-VQTALRQQE--KIERyqe 354
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 206 ------VDLQEALGKKEESEQQLI----------LELEDLRKQL---QQAARELLT-----------LKEEKSVLWNQKE 255
Cdd:COG3096 355 dleeltERLEEQEEVVEEAAEQLAeaearleaaeEEVDSLKSQLadyQQALDVQQTraiqyqqavqaLEKARALCGLPDL 434
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 256 TLTNeAKEREAgspVLPAHKDTALQEEVESLTRVQWESRKQSEKDRATLLSQMRVLESELED-------QLVQHRGCAQL 328
Cdd:COG3096 435 TPEN-AEDYLA---AFRAKEQQATEEVLELEQKLSVADAARRQFEKAYELVCKIAGEVERSQawqtareLLRRYRSQQAL 510
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 329 AEEVATLKQQLAALDKHLRSqrqfmddqaaerehereefQQEIQRLEGQLRQaarprppgpRDSQCVQLDEEVELLQEKl 408
Cdd:COG3096 511 AQRLQQLRAQLAELEQRLRQ-------------------QQNAERLLEEFCQ---------RIGQQLDAAEELEELLAE- 561
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1039732412 409 rekldgfnelvikkdfadqqlliQEEEIKRLEETNASIQRQMVQLQEELEKQKKSMEELKEKE 471
Cdd:COG3096 562 -----------------------LEAQLEELEEQAAEAVEQRSELRQQLEQLRARIKELAARA 601
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
1431-1685 |
4.89e-03 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 42.03 E-value: 4.89e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 1431 LQREGQSSRALEELKLSleKQLAQNNQLCVALKHERAAKDN-------------------LQKELQIEASRCEAL--LAQ 1489
Cdd:pfam17380 308 KAREVERRRKLEEAEKA--RQAEMDRQAAIYAEQERMAMERerelerirqeerkreleriRQEEIAMEISRMRELerLQM 385
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 1490 EKGQLSE-LQKSLEAERSRSL---ELSEALQHERLLTEQLSRNSQEACARQETQVQHALLRKLKAEKTRALELEAMLEKV 1565
Cdd:pfam17380 386 ERQQKNErVRQELEAARKVKIleeERQRKIQQQKVEMEQIRAEQEEARQREVRRLEEERAREMERVRLEEQERQQQVERL 465
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 1566 QKQAAH-----TQQQLEAQAQERCVELRR---EKEVSGNLRSAVDALRTHKqelgcCLQREREKAAWLQAELEQlsARVK 1637
Cdd:pfam17380 466 RQQEEErkrkkLELEKEKRDRKRAEEQRRkilEKELEERKQAMIEEERKRK-----LLEKEMEERQKAIYEEER--RREA 538
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|
gi 1039732412 1638 EQEARKDARRMERRSSRADLDKRKWQRDK--ETLRELEIQRQRDEHKIEQ 1685
Cdd:pfam17380 539 EEERRKQQEMEERRRIQEQMRKATEERSRleAMEREREMMRQIVESEKAR 588
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
1475-1698 |
5.60e-03 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 41.98 E-value: 5.60e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 1475 ELQIEASRCEALlaqeKGQLSELQKSLEAERSRSLELSEALQHERLLTEQLSRNSQEACARQETQVQHA--LLRKLKAEK 1552
Cdd:TIGR02169 675 ELQRLRERLEGL----KRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLeeLEEDLSSLE 750
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 1553 TRALELEAMLEKVQKqaahtqqqleaqaqercvELRREKEVSGNLRSAVDALrthKQELGcclqreREKAAWLQAELEQL 1632
Cdd:TIGR02169 751 QEIENVKSELKELEA------------------RIEELEEDLHKLEEALNDL---EARLS------HSRIPEIQAELSKL 803
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1039732412 1633 SARVKEQEARKDA--RRMERRSSRADLDKRKWQRDKETLRELEIQRQRDEHKIEQLQRLVRELRWKEE 1698
Cdd:TIGR02169 804 EEEVSRIEARLREieQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELE 871
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
131-470 |
5.79e-03 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 41.63 E-value: 5.79e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 131 LLEMALDS-SKQLEEARQLHRCVEREFrhrnEEMAQAMQKQQELLERLREESAAKDRLALELHTAKGLLEGFKVEKVDLQ 209
Cdd:pfam05483 381 IITMELQKkSSELEEMTKFKNNKEVEL----EELKKILAEDEKLLDEKKQFEKIAEELKGKEQELIFLLQAREKEIHDLE 456
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 210 EALGKKEESEQQLILELEDLRKQLQQAARELLTLKEEKSVLWNQKETLTNEAKE------REAGSPVLPAHKDTALQEEV 283
Cdd:pfam05483 457 IQLTAIKTSEEHYLKEVEDLKTELEKEKLKNIELTAHCDKLLLENKELTQEASDmtlelkKHQEDIINCKKQEERMLKQI 536
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 284 ESLTRVQWESRKQSEKDRATLLSQMRVLESELEDqlvQHRGCAQLAEEVATLKQQLAALDKHLRSQRQfmddQAAEREHE 363
Cdd:pfam05483 537 ENLEEKEMNLRDELESVREEFIQKGDEVKCKLDK---SEENARSIEYEVLKKEKQMKILENKCNNLKK----QIENKNKN 609
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 364 REEFQQEIQRLEGqlRQAARPRPPGPRDSQCVQLDEEVELLQEKLREKLDGFNELVIKKDFADQQLL--------IQEEE 435
Cdd:pfam05483 610 IEELHQENKALKK--KGSAENKQLNAYEIKVNKLELELASAKQKFEEIIDNYQKEIEDKKISEEKLLeevekakaIADEA 687
|
330 340 350
....*....|....*....|....*....|....*
gi 1039732412 436 IKRLEETNASIQRQMVQLQEELEKQKKSMEELKEK 470
Cdd:pfam05483 688 VKLQKEIDKRCQHKIAEMVALMEKHKHQYDKIIEE 722
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
160-481 |
6.24e-03 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 41.54 E-value: 6.24e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 160 NEEMAQAMQKQQELlerlrEESAAK-DRLALELHTAKGLLEGFKVEKV-----DLQEALGKKEESEQQLILELEDLRKQL 233
Cdd:TIGR04523 263 NKIKKQLSEKQKEL-----EQNNKKiKELEKQLNQLKSEISDLNNQKEqdwnkELKSELKNQEKKLEEIQNQISQNNKII 337
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 234 QQAARELLTLKEEKSVLWNQKETLTNEAKEREAGSPVLPAHKDTALQE---------EVESLTRVQWESRKQSEKDRATL 304
Cdd:TIGR04523 338 SQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEiknlesqinDLESKIQNQEKLNQQKDEQIKKL 417
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 305 LSQMRVLESELEDQLVQHrgcAQLAEEVATLKQQLAALDKHLRSQRQFMDDQAAEREHEREEF----------QQEIQRL 374
Cdd:TIGR04523 418 QQEKELLEKEIERLKETI---IKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSInkikqnleqkQKELKSK 494
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 375 EGQLRQAarprppgprDSQCVQLDEEVELLQEKLREKLDGFNELVIKKDFADQQLLIQEEEIKR---------LEETNAS 445
Cdd:TIGR04523 495 EKELKKL---------NEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKddfelkkenLEKEIDE 565
|
330 340 350
....*....|....*....|....*....|....*.
gi 1039732412 446 IQRQMVQLQEELEKQKKSMEELKEKEILKQENMGDL 481
Cdd:TIGR04523 566 KNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDL 601
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
225-460 |
6.76e-03 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 41.82 E-value: 6.76e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 225 ELEDLRKQLQQAARELLTLK--EEKSVLWNQKETLTNEAKEREAGSPVLPAHKDTALQEEVESLTRVQWESRKQSEKDRA 302
Cdd:COG4913 236 DLERAHEALEDAREQIELLEpiRELAERYAAARERLAELEYLRAALRLWFAQRRLELLEAELEELRAELARLEAELERLE 315
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 303 TLLSQMRVLESELEDQLVQHRG--CAQLAEEVATLKQQLAALDKHLRSQRQFMDDQAAEREHEREEFQQEIQRLEGQLRq 380
Cdd:COG4913 316 ARLDALREELDELEAQIRGNGGdrLEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLE- 394
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 381 aarprppgprdsqcvQLDEEVELLQEKLREKLDGFNELvikkdfaDQQLLIQEEEIKRLEETNASIQRQMVQLQEELEKQ 460
Cdd:COG4913 395 ---------------ALEEELEALEEALAEAEAALRDL-------RRELRELEAEIASLERRKSNIPARLLALRDALAEA 452
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
225-470 |
6.92e-03 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 41.54 E-value: 6.92e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 225 ELEDLRKQLQQAARELLTLKEEKSVLWNQKETLTNEAKereagspvlpahkdtaLQEEVESLTRVQweSRKQSEKDRATL 304
Cdd:COG3206 183 QLPELRKELEEAEAALEEFRQKNGLVDLSEEAKLLLQQ----------------LSELESQLAEAR--AELAEAEARLAA 244
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 305 LSQMRVLESELEDQLVQHRGCAQLAEEVATLKQQLAALDKHLRSQRQFMddqaaereherEEFQQEIQRLEGQLRQAARp 384
Cdd:COG3206 245 LRAQLGSGPDALPELLQSPVIQQLRAQLAELEAELAELSARYTPNHPDV-----------IALRAQIAALRAQLQQEAQ- 312
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 385 rppgprdSQCVQLDEEVELLQEKLREkldgfnelvikkdfADQQLLIQEEEIKRLeetnASIQRQMVQLQEELEKQKKSM 464
Cdd:COG3206 313 -------RILASLEAELEALQAREAS--------------LQAQLAQLEARLAEL----PELEAELRRLEREVEVARELY 367
|
....*.
gi 1039732412 465 EELKEK 470
Cdd:COG3206 368 ESLLQR 373
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
1198-1570 |
6.97e-03 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 41.29 E-value: 6.97e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 1198 EVFAREQEKAELQPRPYGSNLGDYNSLVQRLEKVIQEQGDPQKVQDHLcLSDRSSLLAEIQALRAQLRMTHLQNQ----- 1272
Cdd:COG4717 67 ELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEEL-REELEKLEKLLQLLPLYQELEALEAElaelp 145
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 1273 EKLQQLCAALTSTEARGSQREHQLRRQVELLAYKVEQEKCIANELQKTLSKEQETASDVRKRLVVEQNAVQDLKSELHAC 1352
Cdd:COG4717 146 ERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEEL 225
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 1353 KQEntsllesLDKVQQEVLRLRYGHVTWSYCGTSSASAGRAVLDGKEKELK------------------VVLEELESERG 1414
Cdd:COG4717 226 EEE-------LEQLENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLsliltiagvlflvlgllaLLFLLLAREKA 298
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 1415 KGQALQAQQEEQQLRYLQREGQSSRALEELKLSLEKQLAQNNQL---CVALKHERAAKDNLQKELQIEAS--RCEALLAQ 1489
Cdd:COG4717 299 SLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELldrIEELQELLREAEELEEELQLEELeqEIAALLAE 378
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 1490 EK-GQLSELQKSLEAERsrslELSEALQHERLLTEQLSRNSQEACARQETQVQHALLRKLKAEKTRALELEAMLEKVQKQ 1568
Cdd:COG4717 379 AGvEDEEELRAALEQAE----EYQELKEELEELEEQLEELLGELEELLEALDEEELEEELEELEEELEELEEELEELREE 454
|
..
gi 1039732412 1569 AA 1570
Cdd:COG4717 455 LA 456
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
160-476 |
7.27e-03 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 41.54 E-value: 7.27e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 160 NEEMAQAMQKQQELLERLREESAAKdrlalelhtaKGLLEGFKVEKVDLQEALGKKEESEQQLILELEDLRKQLQQAARE 239
Cdd:TIGR04523 358 NSEKQRELEEKQNEIEKLKKENQSY----------KQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKE 427
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 240 LLTLKEEKSVLWNQKETLTNEakereagspvlpahkDTALQEEVESLTRvqweSRKQSEKDRATLLSQMRVLESELEdql 319
Cdd:TIGR04523 428 IERLKETIIKNNSEIKDLTNQ---------------DSVKELIIKNLDN----TRESLETQLKVLSRSINKIKQNLE--- 485
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 320 vqhrgcaQLAEEVATLKQQLAALDKH---LRSQRQFMDDQAAEREHEREEFQQEIQRLEGQLRQAARPRPPGPRDSQCVQ 396
Cdd:TIGR04523 486 -------QKQKELKSKEKELKKLNEEkkeLEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDFELKKEN 558
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 397 LDEEVELLQEKLrEKLDGFNELVIKKDFADQQLLIQEE--------EIKRLEETNASIQRQMVQLQEE---LEKQKKSME 465
Cdd:TIGR04523 559 LEKEIDEKNKEI-EELKQTQKSLKKKQEEKQELIDQKEkekkdlikEIEEKEKKISSLEKELEKAKKEnekLSSIIKNIK 637
|
330
....*....|.
gi 1039732412 466 ELKEKeiLKQE 476
Cdd:TIGR04523 638 SKKNK--LKQE 646
|
|
| PRK12704 |
PRK12704 |
phosphodiesterase; Provisional |
143-263 |
8.01e-03 |
|
phosphodiesterase; Provisional
Pssm-ID: 237177 [Multi-domain] Cd Length: 520 Bit Score: 41.30 E-value: 8.01e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 143 EEARQLHRCVEREFRHRNEEMAQAMQKQQELLERLREESAAKDRLALELHTAKGLLEgFKVEKVDLQEALGKKEESEQQL 222
Cdd:PRK12704 64 EEIHKLRNEFEKELRERRNELQKLEKRLLQKEENLDRKLELLEKREEELEKKEKELE-QKQQELEKKEEELEELIEEQLQ 142
|
90 100 110 120
....*....|....*....|....*....|....*....|....*..
gi 1039732412 223 ILE------LEDLRKQLQQAAREllTLKEEKSVLWNQKEtltNEAKE 263
Cdd:PRK12704 143 ELErisgltAEEAKEILLEKVEE--EARHEAAVLIKEIE---EEAKE 184
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
1398-1702 |
9.88e-03 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 41.20 E-value: 9.88e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 1398 KEKELKVVLEELESERGKGQALQAQQEEQQLRYLQREGqSSRALEELKLSLEKQLAQNNQLCVALKHERAAKDNLQK--- 1474
Cdd:PRK03918 215 ELPELREELEKLEKEVKELEELKEEIEELEKELESLEG-SKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKEkae 293
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 1475 ----------ELQIEASRCEALLAQEKGQLSELQKSLEAERSRSLELSEALQHERLLTEQLSRNSQEACARQETQVQHAL 1544
Cdd:PRK03918 294 eyiklsefyeEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEELEERHELYEEAKAKKEE 373
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 1545 LRKLKAEKT--RALELEAMLEKVQKqAAHTQQQLEAQAQERCVELRREKevsGNLRSAVDALRTHKQELGCC---LQRER 1619
Cdd:PRK03918 374 LERLKKRLTglTPEKLEKELEELEK-AKEEIEEEISKITARIGELKKEI---KELKKAIEELKKAKGKCPVCgreLTEEH 449
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039732412 1620 EKA--AWLQAELEQLSARVKEQEAR-KDARRMERRSSRADLDKRKWQRDKETLREL-EIQRQRDEHKIEQLQRLVRELRW 1695
Cdd:PRK03918 450 RKEllEEYTAELKRIEKELKEIEEKeRKLRKELRELEKVLKKESELIKLKELAEQLkELEEKLKKYNLEELEKKAEEYEK 529
|
....*..
gi 1039732412 1696 KEEVSGG 1702
Cdd:PRK03918 530 LKEKLIK 536
|
|
| |
