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Conserved domains on  [gi|1039751015|ref|XP_017172452|]
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golgin subfamily B member 1 isoform X1 [Mus musculus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1830-2754 3.30e-20

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 99.36  E-value: 3.30e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1830 LDQLKGRIAELE-----MEKQKDR-ELSQALENEKNALLTQISAKDselklLEEEVTKRTTLNQQIQEelcrVTKLKETA 1903
Cdd:TIGR02168  188 LDRLEDILNELErqlksLERQAEKaERYKELKAELRELELALLVLR-----LEELREELEELQEELKE----AEEELEEL 258

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1904 EEEKDDLEErlmnQLAELNGSIGNYYQDVTDAQIKNEQLESEMRNLQRCVSELEEEKQQLVKEKTKVESEIRKeymekiq 1983
Cdd:TIGR02168  259 TAELQELEE----KLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEE------- 327

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1984 gaqkgpaNKSHAKELQELLREKQQEVKQLQKDCIRYLERISALEKTVKALEFVHTESQKDLDVTKGNLAQAVEHRKKAQA 2063
Cdd:TIGR02168  328 -------LESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNN 400

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2064 ELSSFKILLDDTQSEAARVLADNLKLKKELQSNKesiksqikqkdedlLRRLEQAEEKHRKEKKNMQEKLDALHREKAHV 2143
Cdd:TIGR02168  401 EIERLEARLERLEDRRERLQQEIEELLKKLEEAE--------------LKELQAELEELEEELEELQEELERLEEALEEL 466

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2144 EETLAEIQVSLTRKDQEMKELQGSLDStlaqlaafTKSMSSLQDDRDRVIDEAKKWERRFGDAIQTKEE--EVRLKEENC 2221
Cdd:TIGR02168  467 REELEEAEQALDAAERELAQLQARLDS--------LERLQENLEGFSEGVKALLKNQSGLSGILGVLSEliSVDEGYEAA 538

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2222 IALKDQLRQMAIHMEELKITVSRLEHDKEIWESKAqTELQHHQKAYDKLQEENKELTSQLEDARQLYHDSKNELTKLESE 2301
Cdd:TIGR02168  539 IEAALGGRLQAVVVENLNAAKKAIAFLKQNELGRV-TFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKA 617

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2302 LKSLKDQ---TTDLNNSLEKCKehENNLEGIIKQQEADIQNCKFsceqletdlaasreltsrlhdeinakeqkIISLLSG 2378
Cdd:TIGR02168  618 LSYLLGGvlvVDDLDNALELAK--KLRPGYRIVTLDGDLVRPGG-----------------------------VITGGSA 666

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2379 KEEAIQLAVEelhqqhsKEIKELENLLSQEEEENVALEEENKRALEKTNQLTEALEAIKKESFEQKAQLDSFVKSMSSLq 2458
Cdd:TIGR02168  667 KTNSSILERR-------REIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARL- 738

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2459 ddrdrivsdyRQLEERHLSAILEKDQLIQDAAAENNKLKEEMRGLRSHMDDLNSENAKLDAELVQYRRDLNEVIAIKDSQ 2538
Cdd:TIGR02168  739 ----------EAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDEL 808

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2539 QKQLldaqlqqnKELRNECTKLEERLKGLEAEKQSLQMSSDALQKEKQGLSKEIKNLQTQLTALQEEGTlgVYHAQLKAK 2618
Cdd:TIGR02168  809 RAEL--------TLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIE--ELESELEAL 878

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2619 EEELQRLNMALSSSQKRTADLEEELvcvqKEATRKVSEIEDQ---LKKELKHLHHDAGIMRNETETAEERVAELARDLVE 2695
Cdd:TIGR02168  879 LNERASLEEALALLRSELEELSEEL----RELESKRSELRREleeLREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLE 954

                          890       900       910       920       930       940
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2696 M-EQKLLTVTKENKDLMAQIQAFGRSMSSLQDSRDHATEELGDLKKKYDASLKELAQLKE 2754
Cdd:TIGR02168  955 EaEALENKIEDDEEEARRRLKRLENKIKELGPVNLAAIEEYEELKERYDFLTAQKEDLTE 1014
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 309-1037 6.83e-19

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 94.74  E-value: 6.83e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  309 AEHNTLKNTMETERQESKTLMEKVELEVAERKLSFHNLQEEMHQLQGQLERAGQAQADLETQYSALQQRHK---TEMEEK 385
Cdd:TIGR02168  242 EELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLAnleRQLEEL 321

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  386 TACILSLQKNEQELQSACAALKEEN----------SKLLQEKHDQAAESAQAMRQLEDQLQQKSKEISQFVNKPNLQKNE 455
Cdd:TIGR02168  322 EAQLEELESKLDELAEELAELEEKLeelkeeleslEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNE 401

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  456 tasqtslpdvnnegdQAVMEETVASLQKRVVELENEKGALL---------LSSGELEELKAENEKLSSRitLLEAQNRAG 526
Cdd:TIGR02168  402 ---------------IERLEARLERLEDRRERLQQEIEELLkkleeaelkELQAELEELEEELEELQEE--LERLEEALE 464

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  527 EADGTVCEVSTAGTTLLNRSDSSpeENGQAVLENTFsQKHKELSVLLVEMKEAQEEIAFLKSQL-QGKRPEGDYE----- 600
Cdd:TIGR02168  465 ELREELEEAEQALDAAERELAQL--QARLDSLERLQ-ENLEGFSEGVKALLKNQSGLSGILGVLsELISVDEGYEaaiea 541

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  601 ---------VLDRREVQLMESEGPPSVTAGDVLCAPSDESSGPAAEEEQAGMKDRHRaSEAGPLNDagMELSSPKLDGV- 670
Cdd:TIGR02168  542 alggrlqavVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIE-GFLGVAKD--LVKFDPKLRKAl 618

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  671 DKSLAVSHVCQCHQGELERLKTqvLELETSLHTAE------------ETYKRNLS--EKVKEISSLTQLSEEVKESAEEA 736
Cdd:TIGR02168  619 SYLLGGVLVVDDLDNALELAKK--LRPGYRIVTLDgdlvrpggvitgGSAKTNSSilERRREIEELEEKIEELEEKIAEL 696

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  737 RSTLAAVTEERDQLlyqvkeLDVLAELRARVQELESSLAEAEKqrglDYESQRAQHNLLTEQIHSLSIEAKSKDVKIEAL 816
Cdd:TIGR02168  697 EKALAELRKELEEL------EEELEQLRKELEELSRQISALRK----DLARLEAEVEQLEERIAQLSKELTELEAEIEEL 766

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  817 QRELDGVQLQFCEQGTQMKTLQSQLEAKEREVREGTERLRDISQEMEGLSQALSQKELEIAKMDQLLLEKQKDVETLQQT 896
Cdd:TIGR02168  767 EERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQ 846

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  897 IQEKDQQVTELSFSMTEKMVQLNEEKfslgveiKTLKEQLNLLSRTEEATKEQVEESGAgSSLKLGHDESGQEGLQQELE 976
Cdd:TIGR02168  847 IEELSEDIESLAAEIEELEELIEELE-------SELEALLNERASLEEALALLRSELEE-LSEELRELESKRSELRRELE 918

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1039751015  977 LLRKESEQRKRKLQAALINRKELLQKVS---QLEEELAKVREDSRKEIPFG-ENERRKLEEDREN 1037
Cdd:TIGR02168  919 ELREKLAQLELRLEGLEVRIDNLQERLSeeySLTLEEAEALENKIEDDEEEaRRRLKRLENKIKE 983
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 730-1635 6.24e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 91.66  E-value: 6.24e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  730 KESAEEARSTLAAVTEERDQLLyqvkelDVLAELRARVQELESSLAEAEKQRGLDYESQRAQHNLLTEQIHSLsieaksk 809
Cdd:TIGR02168  171 KERRKETERKLERTRENLDRLE------DILNELERQLKSLERQAEKAERYKELKAELRELELALLVLRLEEL------- 237

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  810 DVKIEALQRELDGVQLQFCEQGTQMKTLQSQLEAKEREVREGTERLRDISQEMEGLSQALSQKELEIAKMDQLLLEKQKD 889
Cdd:TIGR02168  238 REELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQ 317

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  890 VETLQQTIQEKDQQVTElsfsmtekmvqLNEEKFSLGVEIKTLKEQLNLLSRTEEATKEQVEESgagsslklghdESGQE 969
Cdd:TIGR02168  318 LEELEAQLEELESKLDE-----------LAEELAELEEKLEELKEELESLEAELEELEAELEEL-----------ESRLE 375

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  970 GLQQELELLRKESEQRKRKLQAALINRKELLQKVSQLEEELAkvredsrkeipfgenerRKLEEDRENRDDPEEWGTSKW 1049
Cdd:TIGR02168  376 ELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRE-----------------RLQQEIEELLKKLEEAELKEL 438

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1050 REVEASLKQTISEKEVELEGIRRDLKEKTAAEEELQAVVQRMTRDLQSKTKQIDLLqEEVTENQATIQKLVTGTMDAGNG 1129
Cdd:TIGR02168  439 QAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSL-ERLQENLEGFSEGVKALLKNQSG 517

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1130 GSA-APVKETAASSPPGaggeehWKPELE----GRILDLEKDKTQLQKKLQEALiarkailkKAQEKEKQLKEELREQKD 1204
Cdd:TIGR02168  518 LSGiLGVLSELISVDEG------YEAAIEaalgGRLQAVVVENLNAAKKAIAFL--------KQNELGRVTFLPLDSIKG 583

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1205 AyhHLQGQFHEQNKEKENIADQLRQLqcqarESIDRQLPGTGQqepgppaPSLEGISLEDTepaSESDLHAAQPSPPGET 1284
Cdd:TIGR02168  584 T--EIQGNDREILKNIEGFLGVAKDL-----VKFDPKLRKALS-------YLLGGVLVVDD---LDNALELAKKLRPGYR 646

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1285 AALQATVSVAQIQAQLKEMEVEKEELELKVssiaSELAKKSEEVLLLQDQINEQGLEIQNLKAASVEAQAHTELLKQELE 1364
Cdd:TIGR02168  647 IVTLDGDLVRPGGVITGGSAKTNSSILERR----REIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELE 722

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1365 SSQLKVAGL-EHLKTLQPELDALHKHMGQKEEEVNYLYGQLSEKEQTLTTVQTEMVEQERLIKalhtQLEMQAKEHEERL 1443
Cdd:TIGR02168  723 ELSRQISALrKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIE----ELEAQIEQLKEEL 798

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1444 KQAQVEICELKKKPTELEEE----TNAKQQLQRKLQAALISRKEALKENKSLQEQLSSARDAVERLTKSLADVESQVSVQ 1519
Cdd:TIGR02168  799 KALREALDELRAELTLLNEEaanlRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEAL 878

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1520 NQEKDAVLGKLTILQEERDKLIAEMDRFLLENQSLSGSCESLKLALGGLTEDKEKLMEELESVRSSKMAestewqekhkE 1599
Cdd:TIGR02168  879 LNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSE----------E 948

                          890       900       910
                   ....*....|....*....|....*....|....*.
gi 1039751015 1600 LQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQEL 1635
Cdd:TIGR02168  949 YSLTLEEAEALENKIEDDEEEARRRLKRLENKIKEL 984
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2419-3160 4.93e-10

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 65.85  E-value: 4.93e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2419 NKRALEKTNQLTEALEAIKKEsfEQKAQLDSFVKSMSSLQDDRDR---IVSDYRQLEERHLSAILEKDQLIQDAAAENNK 2495
Cdd:TIGR02168  201 QLKSLERQAEKAERYKELKAE--LRELELALLVLRLEELREELEElqeELKEAEEELEELTAELQELEEKLEELRLEVSE 278

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2496 LKEEMRGLRSHMDDLNSENAKLDAELVQYRRDLNEViaikdSQQKQLLDAQLQQNKELRNEctkLEERLKGLEAEKQSLQ 2575
Cdd:TIGR02168  279 LEEEIEELQKELYALANEISRLEQQKQILRERLANL-----ERQLEELEAQLEELESKLDE---LAEELAELEEKLEELK 350

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2576 MSSDALQKEKQGLSKEIKNLQTQLTALQEEgtlgvyHAQLKAKEEELQRlnmALSSSQKRTADLEEELVCVQKEATRKVS 2655
Cdd:TIGR02168  351 EELESLEAELEELEAELEELESRLEELEEQ------LETLRSKVAQLEL---QIASLNNEIERLEARLERLEDRRERLQQ 421

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2656 EIEDQLKKELKHLHHDAGIMRNETETAEErvaELARDLVEMEQKLLTVTKENKDLMAQIQAFGRSMSSLQdSRDHATEEL 2735
Cdd:TIGR02168  422 EIEELLKKLEEAELKELQAELEELEEELE---ELQEELERLEEALEELREELEEAEQALDAAERELAQLQ-ARLDSLERL 497

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2736 GDLKKKYDASLKELAQLKEWqdssregdvLSQAAFPLSTSENVLSRLEKLNQQLTSKDEQLLhLSSELESSHNQVQSISK 2815
Cdd:TIGR02168  498 QENLEGFSEGVKALLKNQSG---------LSGILGVLSELISVDEGYEAAIEAALGGRLQAV-VVENLNAAKKAIAFLKQ 567

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2816 AmtslqNERDRLWSELEKFRKSE-EGKQRAAAPSAASSPAEVQSLKKAMSSLQNDRDRLL------KELKNLQQQYLQMS 2888
Cdd:TIGR02168  568 N-----ELGRVTFLPLDSIKGTEiQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLggvlvvDDLDNALELAKKLR 642

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2889 QEMT-------------------------------ELRPLKAQLQESQDQTKALQVMEEELRQENLSWQHELRQLRMEKN 2937
Cdd:TIGR02168  643 PGYRivtldgdlvrpggvitggsaktnssilerrrEIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELE 722

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2938 SWELHERRMKEQfLMAISDKDQQLGHLQSLLRELRSSSQAQILSTQYQR-QASPETSASLDGSQKLVYETELLRTQLNDS 3016
Cdd:TIGR02168  723 ELSRQISALRKD-LARLEAEVEQLEERIAQLSKELTELEAEIEELEERLeEAEEELAEAEAEIEELEAQIEQLKEELKAL 801

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 3017 LKEIHQKELRIQQLNSKFSQLLEEKNVLSTQLSDASQSLRENQHHYSNLFNHCAILEKEVQKLQAGP--LNTDVapgapq 3094
Cdd:TIGR02168  802 REALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIeeLESEL------ 875

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1039751015 3095 EKNGMHRKSEPETTGEEQPSFSEVQQQLCNTKQDLRELKKLLEEERDQRLTAENALSLAKEQIRRL 3160
Cdd:TIGR02168  876 EALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNL 941
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 47-529 1.16e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 54.56  E-value: 1.16e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015   47 ESTQEDALHRLAEAEKLVVELKDIISQKDVQLQQKDEALQEEKKAAENKIKKIKlHAKAKIMSLNKHMEEIktqggaalp 126
Cdd:COG1196    252 EAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIA-RLEERRRELEERLEEL--------- 321

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  127 pEAQAEELSKHNKSSTEEEMEIEKIKHELQEKEKLISSLQAQLDQSEQASQLDKSSAEMEDFVLMKQQLQEKEELISTLQ 206
Cdd:COG1196    322 -EEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAA 400

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  207 TQLSQTQAEQAAQlssmqqvvrEKDARFETQVRLHEDELLQLVTQSDVEtemQQKLRVMQRKLEEHEEALLGRAQVVDLL 286
Cdd:COG1196    401 QLEELEEAEEALL---------ERLERLEEELEELEEALAELEEEEEEE---EEALEEAAEEEAELEEEEEALLELLAEL 468

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  287 QKELTSAEQRNQVLSQQLQLLEAEHNTLKNTMETERQESKTLMEKVELEVAERklsfhnLQEEMHQLQGQLERAGQAQAD 366
Cdd:COG1196    469 LEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRG------LAGAVAVLIGVEAAYEAALEA 542

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  367 LETqySALQQRHKTEMEEKTACILSLQKNEQELQSACAALKEENSKLLQEKHDQAAEsAQAMRQLEDQLQQKSKEISQFV 446
Cdd:COG1196    543 ALA--AALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAI-GAAVDLVASDLREADARYYVLG 619

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  447 NkpnlqkneTASQTSLPDVNNEGDQAVMEETVASLQKRVVELENEKGALLLSSGELEELKAENEKLSSRITLLEAQNRAG 526
Cdd:COG1196    620 D--------TLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEE 691


                   ...
gi 1039751015  527 EAD 529
Cdd:COG1196    692 ELE 694
EnvC super family cl34844
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1710-1921 4.79e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG4942:

Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.53  E-value: 4.79e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1710 SSLKEELEKITLEHKTLSKEFEALMAEKDALSEETRNLKLQVEA--QVLKQASLEATEKSDEPKDVIEEVTQAVVGKSQE 1787
Cdd:COG4942     23 AEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAAlaRRIRALEQELAALEAELAELEKEIAELRAELEAQ 102

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1788 RDALSDSAKledsEAILMGDGAKPGV---SETFSSHDDIKNYLQQL-DQLKGRIAELEMEKQKDRELSQALENEKNALLT 1863
Cdd:COG4942    103 KEELAELLR----ALYRLGRQPPLALllsPEDFLDAVRRLQYLKYLaPARREQAEELRADLAELAALRAELEAERAELEA 178

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1039751015 1864 QISAKDSELKLLEEEVTKRTTLNQQIQEELcrvtKLKETAEEEKDDLEERLMNQLAEL 1921
Cdd:COG4942    179 LLAELEEERAALEALKAERQKLLARLEKEL----AELAAELAELQQEAEELEALIARL 232
 
Name Accession Description Interval E-value
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1830-2754 3.30e-20

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 99.36  E-value: 3.30e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1830 LDQLKGRIAELE-----MEKQKDR-ELSQALENEKNALLTQISAKDselklLEEEVTKRTTLNQQIQEelcrVTKLKETA 1903
Cdd:TIGR02168  188 LDRLEDILNELErqlksLERQAEKaERYKELKAELRELELALLVLR-----LEELREELEELQEELKE----AEEELEEL 258

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1904 EEEKDDLEErlmnQLAELNGSIGNYYQDVTDAQIKNEQLESEMRNLQRCVSELEEEKQQLVKEKTKVESEIRKeymekiq 1983
Cdd:TIGR02168  259 TAELQELEE----KLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEE------- 327

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1984 gaqkgpaNKSHAKELQELLREKQQEVKQLQKDCIRYLERISALEKTVKALEFVHTESQKDLDVTKGNLAQAVEHRKKAQA 2063
Cdd:TIGR02168  328 -------LESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNN 400

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2064 ELSSFKILLDDTQSEAARVLADNLKLKKELQSNKesiksqikqkdedlLRRLEQAEEKHRKEKKNMQEKLDALHREKAHV 2143
Cdd:TIGR02168  401 EIERLEARLERLEDRRERLQQEIEELLKKLEEAE--------------LKELQAELEELEEELEELQEELERLEEALEEL 466

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2144 EETLAEIQVSLTRKDQEMKELQGSLDStlaqlaafTKSMSSLQDDRDRVIDEAKKWERRFGDAIQTKEE--EVRLKEENC 2221
Cdd:TIGR02168  467 REELEEAEQALDAAERELAQLQARLDS--------LERLQENLEGFSEGVKALLKNQSGLSGILGVLSEliSVDEGYEAA 538

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2222 IALKDQLRQMAIHMEELKITVSRLEHDKEIWESKAqTELQHHQKAYDKLQEENKELTSQLEDARQLYHDSKNELTKLESE 2301
Cdd:TIGR02168  539 IEAALGGRLQAVVVENLNAAKKAIAFLKQNELGRV-TFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKA 617

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2302 LKSLKDQ---TTDLNNSLEKCKehENNLEGIIKQQEADIQNCKFsceqletdlaasreltsrlhdeinakeqkIISLLSG 2378
Cdd:TIGR02168  618 LSYLLGGvlvVDDLDNALELAK--KLRPGYRIVTLDGDLVRPGG-----------------------------VITGGSA 666

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2379 KEEAIQLAVEelhqqhsKEIKELENLLSQEEEENVALEEENKRALEKTNQLTEALEAIKKESFEQKAQLDSFVKSMSSLq 2458
Cdd:TIGR02168  667 KTNSSILERR-------REIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARL- 738

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2459 ddrdrivsdyRQLEERHLSAILEKDQLIQDAAAENNKLKEEMRGLRSHMDDLNSENAKLDAELVQYRRDLNEVIAIKDSQ 2538
Cdd:TIGR02168  739 ----------EAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDEL 808

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2539 QKQLldaqlqqnKELRNECTKLEERLKGLEAEKQSLQMSSDALQKEKQGLSKEIKNLQTQLTALQEEGTlgVYHAQLKAK 2618
Cdd:TIGR02168  809 RAEL--------TLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIE--ELESELEAL 878

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2619 EEELQRLNMALSSSQKRTADLEEELvcvqKEATRKVSEIEDQ---LKKELKHLHHDAGIMRNETETAEERVAELARDLVE 2695
Cdd:TIGR02168  879 LNERASLEEALALLRSELEELSEEL----RELESKRSELRREleeLREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLE 954

                          890       900       910       920       930       940
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2696 M-EQKLLTVTKENKDLMAQIQAFGRSMSSLQDSRDHATEELGDLKKKYDASLKELAQLKE 2754
Cdd:TIGR02168  955 EaEALENKIEDDEEEARRRLKRLENKIKELGPVNLAAIEEYEELKERYDFLTAQKEDLTE 1014
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 309-1037 6.83e-19

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 94.74  E-value: 6.83e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  309 AEHNTLKNTMETERQESKTLMEKVELEVAERKLSFHNLQEEMHQLQGQLERAGQAQADLETQYSALQQRHK---TEMEEK 385
Cdd:TIGR02168  242 EELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLAnleRQLEEL 321

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  386 TACILSLQKNEQELQSACAALKEEN----------SKLLQEKHDQAAESAQAMRQLEDQLQQKSKEISQFVNKPNLQKNE 455
Cdd:TIGR02168  322 EAQLEELESKLDELAEELAELEEKLeelkeeleslEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNE 401

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  456 tasqtslpdvnnegdQAVMEETVASLQKRVVELENEKGALL---------LSSGELEELKAENEKLSSRitLLEAQNRAG 526
Cdd:TIGR02168  402 ---------------IERLEARLERLEDRRERLQQEIEELLkkleeaelkELQAELEELEEELEELQEE--LERLEEALE 464

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  527 EADGTVCEVSTAGTTLLNRSDSSpeENGQAVLENTFsQKHKELSVLLVEMKEAQEEIAFLKSQL-QGKRPEGDYE----- 600
Cdd:TIGR02168  465 ELREELEEAEQALDAAERELAQL--QARLDSLERLQ-ENLEGFSEGVKALLKNQSGLSGILGVLsELISVDEGYEaaiea 541

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  601 ---------VLDRREVQLMESEGPPSVTAGDVLCAPSDESSGPAAEEEQAGMKDRHRaSEAGPLNDagMELSSPKLDGV- 670
Cdd:TIGR02168  542 alggrlqavVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIE-GFLGVAKD--LVKFDPKLRKAl 618

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  671 DKSLAVSHVCQCHQGELERLKTqvLELETSLHTAE------------ETYKRNLS--EKVKEISSLTQLSEEVKESAEEA 736
Cdd:TIGR02168  619 SYLLGGVLVVDDLDNALELAKK--LRPGYRIVTLDgdlvrpggvitgGSAKTNSSilERRREIEELEEKIEELEEKIAEL 696

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  737 RSTLAAVTEERDQLlyqvkeLDVLAELRARVQELESSLAEAEKqrglDYESQRAQHNLLTEQIHSLSIEAKSKDVKIEAL 816
Cdd:TIGR02168  697 EKALAELRKELEEL------EEELEQLRKELEELSRQISALRK----DLARLEAEVEQLEERIAQLSKELTELEAEIEEL 766

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  817 QRELDGVQLQFCEQGTQMKTLQSQLEAKEREVREGTERLRDISQEMEGLSQALSQKELEIAKMDQLLLEKQKDVETLQQT 896
Cdd:TIGR02168  767 EERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQ 846

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  897 IQEKDQQVTELSFSMTEKMVQLNEEKfslgveiKTLKEQLNLLSRTEEATKEQVEESGAgSSLKLGHDESGQEGLQQELE 976
Cdd:TIGR02168  847 IEELSEDIESLAAEIEELEELIEELE-------SELEALLNERASLEEALALLRSELEE-LSEELRELESKRSELRRELE 918

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1039751015  977 LLRKESEQRKRKLQAALINRKELLQKVS---QLEEELAKVREDSRKEIPFG-ENERRKLEEDREN 1037
Cdd:TIGR02168  919 ELREKLAQLELRLEGLEVRIDNLQERLSeeySLTLEEAEALENKIEDDEEEaRRRLKRLENKIKE 983
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 730-1635 6.24e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 91.66  E-value: 6.24e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  730 KESAEEARSTLAAVTEERDQLLyqvkelDVLAELRARVQELESSLAEAEKQRGLDYESQRAQHNLLTEQIHSLsieaksk 809
Cdd:TIGR02168  171 KERRKETERKLERTRENLDRLE------DILNELERQLKSLERQAEKAERYKELKAELRELELALLVLRLEEL------- 237

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  810 DVKIEALQRELDGVQLQFCEQGTQMKTLQSQLEAKEREVREGTERLRDISQEMEGLSQALSQKELEIAKMDQLLLEKQKD 889
Cdd:TIGR02168  238 REELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQ 317

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  890 VETLQQTIQEKDQQVTElsfsmtekmvqLNEEKFSLGVEIKTLKEQLNLLSRTEEATKEQVEESgagsslklghdESGQE 969
Cdd:TIGR02168  318 LEELEAQLEELESKLDE-----------LAEELAELEEKLEELKEELESLEAELEELEAELEEL-----------ESRLE 375

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  970 GLQQELELLRKESEQRKRKLQAALINRKELLQKVSQLEEELAkvredsrkeipfgenerRKLEEDRENRDDPEEWGTSKW 1049
Cdd:TIGR02168  376 ELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRE-----------------RLQQEIEELLKKLEEAELKEL 438

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1050 REVEASLKQTISEKEVELEGIRRDLKEKTAAEEELQAVVQRMTRDLQSKTKQIDLLqEEVTENQATIQKLVTGTMDAGNG 1129
Cdd:TIGR02168  439 QAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSL-ERLQENLEGFSEGVKALLKNQSG 517

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1130 GSA-APVKETAASSPPGaggeehWKPELE----GRILDLEKDKTQLQKKLQEALiarkailkKAQEKEKQLKEELREQKD 1204
Cdd:TIGR02168  518 LSGiLGVLSELISVDEG------YEAAIEaalgGRLQAVVVENLNAAKKAIAFL--------KQNELGRVTFLPLDSIKG 583

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1205 AyhHLQGQFHEQNKEKENIADQLRQLqcqarESIDRQLPGTGQqepgppaPSLEGISLEDTepaSESDLHAAQPSPPGET 1284
Cdd:TIGR02168  584 T--EIQGNDREILKNIEGFLGVAKDL-----VKFDPKLRKALS-------YLLGGVLVVDD---LDNALELAKKLRPGYR 646

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1285 AALQATVSVAQIQAQLKEMEVEKEELELKVssiaSELAKKSEEVLLLQDQINEQGLEIQNLKAASVEAQAHTELLKQELE 1364
Cdd:TIGR02168  647 IVTLDGDLVRPGGVITGGSAKTNSSILERR----REIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELE 722

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1365 SSQLKVAGL-EHLKTLQPELDALHKHMGQKEEEVNYLYGQLSEKEQTLTTVQTEMVEQERLIKalhtQLEMQAKEHEERL 1443
Cdd:TIGR02168  723 ELSRQISALrKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIE----ELEAQIEQLKEEL 798

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1444 KQAQVEICELKKKPTELEEE----TNAKQQLQRKLQAALISRKEALKENKSLQEQLSSARDAVERLTKSLADVESQVSVQ 1519
Cdd:TIGR02168  799 KALREALDELRAELTLLNEEaanlRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEAL 878

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1520 NQEKDAVLGKLTILQEERDKLIAEMDRFLLENQSLSGSCESLKLALGGLTEDKEKLMEELESVRSSKMAestewqekhkE 1599
Cdd:TIGR02168  879 LNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSE----------E 948

                          890       900       910
                   ....*....|....*....|....*....|....*.
gi 1039751015 1600 LQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQEL 1635
Cdd:TIGR02168  949 YSLTLEEAEALENKIEDDEEEARRRLKRLENKIKEL 984
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 758-1400 5.94e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 78.44  E-value: 5.94e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  758 DVLAELRARVQELESSLAEAEKQRGLDYESQRAQHNLLTEQIHSLSIEAKSKDVKIEALQRELdgvqlqfceqgtqmKTL 837
Cdd:COG1196    193 DILGELERQLEPLERQAEKAERYRELKEELKELEAELLLLKLRELEAELEELEAELEELEAEL--------------EEL 258

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  838 QSQLEAKEREVREGTERLRDISQEMEGLSQALSQKELEIAKMDQLLLEKQKDVETLQQTIQEKDQQVTELsfsmTEKMVQ 917
Cdd:COG1196    259 EAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAEL----EEELEE 334

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  918 LNEEKFSLGVEIKTLKEQLNLLSRTEEATKEQVEEsgagsslklghDESGQEGLQQELELLRKESEQRKRKLQAALINRK 997
Cdd:COG1196    335 LEEELEELEEELEEAEEELEEAEAELAEAEEALLE-----------AEAELAEAEEELEELAEELLEALRAAAELAAQLE 403

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  998 ELLQKVSQLEEELAKVREDSRKEipfgENERRKLEEDRENRddpeewgtskwREVEASLKQTISEKEVELEGIRRDLKEK 1077
Cdd:COG1196    404 ELEEAEEALLERLERLEEELEEL----EEALAELEEEEEEE-----------EEALEEAAEEEAELEEEEEALLELLAEL 468

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1078 TAAEEELQAVVQRMTRDLQSKTKQIDLLQEEVTEnqatiqklvtgtMDAGNGGSAAPVKETAASSPPGAGGEEHWKPELE 1157
Cdd:COG1196    469 LEEAALLEAALAELLEELAEAAARLLLLLEAEAD------------YEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAY 536

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1158 GRILDLEKDKTQLQKKLQEALIARKAILKKAQEKEKQLKEELREQKDAYHHLQGQFHEQNKEKENIADQLRQLQCQARES 1237
Cdd:COG1196    537 EAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYY 616

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1238 IDRQLPGTGQQEPGPPAPSLEGISLEDTEPASESDLHAAQPSPPGETAALQATVSVAQIQAQLKEMEVEKEELELKVSSI 1317
Cdd:COG1196    617 VLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELE 696

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1318 ASELAKKSEEVLLLQDQINEQGLEIQNLKAASVEAQAHTELLKQELESSQLKVAGLEHLKTLQPELDALHKHMGQKEEEV 1397
Cdd:COG1196    697 EALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREI 776


                   ...
gi 1039751015 1398 NYL 1400
Cdd:COG1196    777 EAL 779
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1403-1976 8.77e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 78.05  E-value: 8.77e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1403 QLSEKEQTLTTVQTEMVEQERLIKALHTQLEMQAKEHEERLKQAQVEICELKKKPTELEE----ETNAKQQLQRKLQAAL 1478
Cdd:COG1196    243 ELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQdiarLEERRRELEERLEELE 322

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1479 ISRKEALKENKSLQEQLSSARDAVERLTKSLADVESQVSVQNQEKDAVLGKLTILQEERDKLIAEMDRFLLENQSLSGSC 1558
Cdd:COG1196    323 EELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQL 402

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1559 ESLKLALGGLTEDKEKLMEELESVRSSKMAESTEWQEKHKELQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQELYAK 1638
Cdd:COG1196    403 EELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAEL 482

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1639 LRSTESDKREREKQLQDAEQEMEEMKEKMRKFAKSKQQKILEL--EEENDRLRAEAQPVGGTGESMEALLSSNSSLKEEL 1716
Cdd:COG1196    483 LEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAvaVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAA 562

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1717 EKITLEHKTLSKEFEAL-MAEKDALSEETRNLKLQVEAQVLKQASLEATEKSDEPKDVIEEVTQAVVGKSQERDALSDSA 1795
Cdd:COG1196    563 IEYLKAAKAGRATFLPLdKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTL 642

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1796 KLEDSEAILMGDGAKPGVSETfsshddiknylqqLDQLKGRIAELEMEKQKDRELSQALENEKNALLTQISAKDSELKLL 1875
Cdd:COG1196    643 AGRLREVTLEGEGGSAGGSLT-------------GGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEEREL 709

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1876 EEEVTKRTTLNQQIQEELCRVTKLKETAEEEKDDLEERLMNQLAELNGSIgnyyQDVTDAQIKNEQLESEMRNLQRcV-- 1953
Cdd:COG1196    710 AEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEP----PDLEELERELERLEREIEALGP-Vnl 784

                          570       580
                   ....*....|....*....|....*....
gi 1039751015 1954 ------SELEEEKQQLVKEKTKVESEIRK 1976
Cdd:COG1196    785 laieeyEELEERYDFLSEQREDLEEARET 813
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 684-1258 1.21e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 74.20  E-value: 1.21e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  684 QGELERLKTQVLELETSLHTAEETYKRNLSEKVKEISSLTQLSEEVKESAEEARSTLAAVTEERDQLLYQVKELDVLAEL 763
Cdd:COG1196    238 EAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEER 317

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  764 RARVQELESSLAEAEKQRGLDYESQRAQHNLLTEQIHSLSIEAKSKDVKIEALQRELDGVQLQFCEQGTQMKTLQSQLEA 843
Cdd:COG1196    318 LEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAE 397

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  844 KEREVREGTERLRDISQEMEGLSQALSQKELEIAKMDQLLLEKQKDVETLQQTIQEKDQQVTELsfsmTEKMVQLNEEKF 923
Cdd:COG1196    398 LAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEAL----LELLAELLEEAA 473

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  924 SLGVEIKTLKEQLNLLSRTEEATKE-QVEESGAGSSLKLGHDESGQEGLQQELELLRKESEQRKRKLQAALInrkELLQK 1002
Cdd:COG1196    474 LLEAALAELLEELAEAAARLLLLLEaEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALA---AALQN 550

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1003 VSQLEEELAKVREDSRKEIPFGENERRKLEEDRENRDDPeewgtskwrevEASLKQTISEKEVELEGIRRDLKEKTAAEE 1082
Cdd:COG1196    551 IVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALA-----------AALARGAIGAAVDLVASDLREADARYYVLG 619

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1083 ELQAVVQRMTRDLQSKTKQIDLLQEEVTEnqatiqklVTGTMDAGNGGSAapvketaassppgaggeehwkpelEGRILD 1162
Cdd:COG1196    620 DTLLGRTLVAARLEAALRRAVTLAGRLRE--------VTLEGEGGSAGGS------------------------LTGGSR 667

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1163 LEKDKTQLQKKLQEALIARKAILKKAQEKEKQLKEELREQKDAYHHLQGQFHEQNKEKENIADQLRQLQCQARESIDRQL 1242
Cdd:COG1196    668 RELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEEL 747

                          570
                   ....*....|....*.
gi 1039751015 1243 PGTGQQEPGPPAPSLE 1258
Cdd:COG1196    748 LEEEALEELPEPPDLE 763
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2419-3160 4.93e-10

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 65.85  E-value: 4.93e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2419 NKRALEKTNQLTEALEAIKKEsfEQKAQLDSFVKSMSSLQDDRDR---IVSDYRQLEERHLSAILEKDQLIQDAAAENNK 2495
Cdd:TIGR02168  201 QLKSLERQAEKAERYKELKAE--LRELELALLVLRLEELREELEElqeELKEAEEELEELTAELQELEEKLEELRLEVSE 278

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2496 LKEEMRGLRSHMDDLNSENAKLDAELVQYRRDLNEViaikdSQQKQLLDAQLQQNKELRNEctkLEERLKGLEAEKQSLQ 2575
Cdd:TIGR02168  279 LEEEIEELQKELYALANEISRLEQQKQILRERLANL-----ERQLEELEAQLEELESKLDE---LAEELAELEEKLEELK 350

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2576 MSSDALQKEKQGLSKEIKNLQTQLTALQEEgtlgvyHAQLKAKEEELQRlnmALSSSQKRTADLEEELVCVQKEATRKVS 2655
Cdd:TIGR02168  351 EELESLEAELEELEAELEELESRLEELEEQ------LETLRSKVAQLEL---QIASLNNEIERLEARLERLEDRRERLQQ 421

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2656 EIEDQLKKELKHLHHDAGIMRNETETAEErvaELARDLVEMEQKLLTVTKENKDLMAQIQAFGRSMSSLQdSRDHATEEL 2735
Cdd:TIGR02168  422 EIEELLKKLEEAELKELQAELEELEEELE---ELQEELERLEEALEELREELEEAEQALDAAERELAQLQ-ARLDSLERL 497

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2736 GDLKKKYDASLKELAQLKEWqdssregdvLSQAAFPLSTSENVLSRLEKLNQQLTSKDEQLLhLSSELESSHNQVQSISK 2815
Cdd:TIGR02168  498 QENLEGFSEGVKALLKNQSG---------LSGILGVLSELISVDEGYEAAIEAALGGRLQAV-VVENLNAAKKAIAFLKQ 567

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2816 AmtslqNERDRLWSELEKFRKSE-EGKQRAAAPSAASSPAEVQSLKKAMSSLQNDRDRLL------KELKNLQQQYLQMS 2888
Cdd:TIGR02168  568 N-----ELGRVTFLPLDSIKGTEiQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLggvlvvDDLDNALELAKKLR 642

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2889 QEMT-------------------------------ELRPLKAQLQESQDQTKALQVMEEELRQENLSWQHELRQLRMEKN 2937
Cdd:TIGR02168  643 PGYRivtldgdlvrpggvitggsaktnssilerrrEIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELE 722

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2938 SWELHERRMKEQfLMAISDKDQQLGHLQSLLRELRSSSQAQILSTQYQR-QASPETSASLDGSQKLVYETELLRTQLNDS 3016
Cdd:TIGR02168  723 ELSRQISALRKD-LARLEAEVEQLEERIAQLSKELTELEAEIEELEERLeEAEEELAEAEAEIEELEAQIEQLKEELKAL 801

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 3017 LKEIHQKELRIQQLNSKFSQLLEEKNVLSTQLSDASQSLRENQHHYSNLFNHCAILEKEVQKLQAGP--LNTDVapgapq 3094
Cdd:TIGR02168  802 REALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIeeLESEL------ 875

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1039751015 3095 EKNGMHRKSEPETTGEEQPSFSEVQQQLCNTKQDLRELKKLLEEERDQRLTAENALSLAKEQIRRL 3160
Cdd:TIGR02168  876 EALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNL 941
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1911-2481 1.71e-09

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 63.93  E-value: 1.71e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1911 EERLMNQLAELNGSIGNYYQDVTDAQIKNEQLESEMRNLQRCVSELEEEKQ---QLVKEKTKVESEIRKEyMEKIQGAQK 1987
Cdd:PRK03918   188 TENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEeieELEKELESLEGSKRKL-EEKIRELEE 266

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1988 GPANKshaKELQELLREKQQEVKQLQKDCIRYLERISALEKTVKALefvhtesqKDLDVTKGNLAQAVEHRKKAQAELSS 2067
Cdd:PRK03918   267 RIEEL---KKEIEELEEKVKELKELKEKAEEYIKLSEFYEEYLDEL--------REIEKRLSRLEEEINGIEERIKELEE 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2068 FKILLDDTQseaarvladnlKLKKELQSNKESIKSQIKQKDEdlLRRLEQAEEKHRKEKKN-----MQEKLDALHREKAH 2142
Cdd:PRK03918   336 KEERLEELK-----------KKLKELEKRLEELEERHELYEE--AKAKKEELERLKKRLTGltpekLEKELEELEKAKEE 402

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2143 VEETLAEIQVSLTRKDQEMKELQGSL-------------------DSTLAQLAAFTKSMSSLQDDRDRVIDEAKKWERRF 2203
Cdd:PRK03918   403 IEEEISKITARIGELKKEIKELKKAIeelkkakgkcpvcgrelteEHRKELLEEYTAELKRIEKELKEIEEKERKLRKEL 482

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2204 gdaiqTKEEEVRLKEENCIALKDQLRQMAIHMEELKitvsrlEHDKEIWESKAqTELQHHQKAYDKLQEENKELTSQLED 2283
Cdd:PRK03918   483 -----RELEKVLKKESELIKLKELAEQLKELEEKLK------KYNLEELEKKA-EEYEKLKEKLIKLKGEIKSLKKELEK 550

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2284 ARQLyhdsKNELTKLESELKSLKDQTTDLNNSLEKCK-EHENNLEGIIKQQEA------DIQNCKFSCEQLETDLAASRE 2356
Cdd:PRK03918   551 LEEL----KKKLAELEKKLDELEEELAELLKELEELGfESVEELEERLKELEPfyneylELKDAEKELEREEKELKKLEE 626

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2357 LTSRLHDEINAKEQKIISLLSGKEEAIQLAVEELHQQHSKEIKELENLLSQEEEENVALEEENKRALEKTNQLTEALEAI 2436
Cdd:PRK03918   627 ELDKAFEELAETEKRLEELRKELEELEKKYSEEEYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEER 706

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*
gi 1039751015 2437 KKesfeQKAQLDSFVKSMSSLQDDRDRIVSDYRQLEERHLSAILE 2481
Cdd:PRK03918   707 EK----AKKELEKLEKALERVEELREKVKKYKALLKERALSKVGE 747
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 734-1220 6.53e-09

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 62.16  E-value: 6.53e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  734 EEARSTLAAVTEERDQLLYQVKELDVLAELRARVQELESSLAEAEKQRGLDYESQ-RAQHNLLTEQIHSLSIEAKSKDVK 812
Cdd:pfam12128  237 MKIRPEFTKLQQEFNTLESAELRLSHLHFGYKSDETLIASRQEERQETSAELNQLlRTLDDQWKEKRDELNGELSAADAA 316

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  813 IEALQRELDGVQ---LQFCEQG--------TQMKTLQSQLEAKEREVREGTERLRDISQEMEGLSQALSQK-ELEIAKMD 880
Cdd:pfam12128  317 VAKDRSELEALEdqhGAFLDADietaaadqEQLPSWQSELENLEERLKALTGKHQDVTAKYNRRRSKIKEQnNRDIAGIK 396

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  881 QLLlEKQKDVETLQQTIQEKD--QQVTELSFSMTEKMVQLNEEKFSLGVEIKTLKEQLNLLSRTEE--ATKEQVEESGAG 956
Cdd:pfam12128  397 DKL-AKIREARDRQLAVAEDDlqALESELREQLEAGKLEFNEEEYRLKSRLGELKLRLNQATATPEllLQLENFDERIER 475

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  957 SSLKLGHDESGQEGLQQELELLRKESEQRKRKLQAALINRKELLQKVSQLEEEL----AKVREDSRKEIP-FGENERRKL 1031
Cdd:pfam12128  476 AREEQEAANAEVERLQSELRQARKRRDQASEALRQASRRLEERQSALDELELQLfpqaGTLLHFLRKEAPdWEQSIGKVI 555

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1032 EEDRENRDD--PEEWgtskwrevEASLKQTISEKEVELEGIRRDLKEKTAAEEELQAVVQRMTRDLQSKTKQIDLLQEEV 1109
Cdd:pfam12128  556 SPELLHRTDldPEVW--------DGSVGGELNLYGVKLDLKRIDVPEWAASEEELRERLDKAEEALQSAREKQAAAEEQL 627

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1110 TENQATIQKLVTGTMDAGNGGSAApvketaassppgaggeehwkpelEGRILDLEKDKTQLQKKLQEALIARKA-ILKKA 1188
Cdd:pfam12128  628 VQANGELEKASREETFARTALKNA-----------------------RLDLRRLFDEKQSEKDKKNKALAERKDsANERL 684

                          490       500       510
                   ....*....|....*....|....*....|..
gi 1039751015 1189 QEKEKQLKEELREQKDAYHHLQGQFHEQNKEK 1220
Cdd:pfam12128  685 NSLEAQLKQLDKKHQAWLEEQKEQKREARTEK 716
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1823-2594 1.22e-07

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 58.06  E-value: 1.22e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1823 IKNYLQQLDQLKGRIAELEMEKQKDRELSQALENEKNALLTQISAKDSELKLLEEEVTKRttlnQQIQEELCRVTKLKET 1902
Cdd:pfam02463  281 KKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEEL----EKELKELEIKREAEEE 356

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1903 AEEEKDDLEERLMNQLAELNGSIGNYYQDVTDAQIKNEQLESEMRNLQRCVS---ELEEEKQQLVKEKTKVESEIRKEYM 1979
Cdd:pfam02463  357 EEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQlllELARQLEDLLKEEKKEELEILEEEE 436

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1980 EKIQGAQKGPANKSHAKELQELLREKQQEVKQLQKDcirylerisalektvkalefvhtesqkdldvtKGNLAQAVEHRK 2059
Cdd:pfam02463  437 ESIELKQGKLTEEKEELEKQELKLLKDELELKKSED--------------------------------LLKETQLVKLQE 484

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2060 KAQAELSSFKILLDDTQSEAARVLADNLKLKKELQSNKESIKSQIKQKDEDLLRRLEQAEEKHRKEKKNMQEKLDALHRE 2139
Cdd:pfam02463  485 QLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQ 564

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2140 KAHVEETLAEIQVSLTRKDQEMKELQGSLDSTLAQLAAfTKSMSSLQDDRDRVIDEAKKWERRFGDAIQTKEEEVRLKEE 2219
Cdd:pfam02463  565 KLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPI-LNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKA 643

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2220 NCIALKDQLRQMAIHMEELKITVSRLEHDKEIWESKAQTELQHHQKAYDKLQEENKELTSQLEDARQLYHDSKNELTKLE 2299
Cdd:pfam02463  644 KESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELL 723

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2300 SELKSLKDQTTDLNNSLEKCKEHENNLEGIIKQQEADIQNCKFSCEQLETDLAASReltsRLHDEINAKEQKIISLLSGK 2379
Cdd:pfam02463  724 ADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEE----REKTEKLKVEEEKEEKLKAQ 799

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2380 EEAIQLAVEELHQQHSKEIKELENLLSQEEEENVALEEENKRALEKTNQLTEALEAIKKESFEQKAQLDSFVKSMSSLQD 2459
Cdd:pfam02463  800 EEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEEL 879

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2460 DRDRIVsDYRQLEERHLSAILEKDQLIQDAAAENNKLKEEMRGLRSHMDDLNSENAKLDAELVQYRRDLNEVIAIKDSQQ 2539
Cdd:pfam02463  880 EEQKLK-DELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEE 958

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1039751015 2540 KQLLDAQLQQNKELRN-------ECTKLEERLKGLEAEKQSLQMSSDALQKEKQGLSKEIKN 2594
Cdd:pfam02463  959 EERNKRLLLAKEELGKvnlmaieEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQRLK 1020
PTZ00121 PTZ00121
MAEBL; Provisional
 965-1693 2.86e-07

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 56.69  E-value: 2.86e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  965 ESGQEGLQQELELLRKESEQRKRKLQAALINRKELLQKVSQLEEElAKVREDSRKEIPFGENERRKLEEDRENRDDPEEW 1044
Cdd:PTZ00121  1101 EEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEA-RKAEDAKRVEIARKAEDARKAEEARKAEDAKKAE 1179

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1045 GTSKWREVEASLKQTISEKEVELEGIRRDLKEKTAAE---EELQAVVQRMTRDLQSKTKQIDLLQEEVTENQATIQKLVT 1121
Cdd:PTZ00121  1180 AARKAEEVRKAEELRKAEDARKAEAARKAEEERKAEEarkAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEE 1259

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1122 GTMDAGNGGSAAPVKETAASSPPGAGGEEHWKPElEGRILDLEKDKTQLQKKLQEALIARKAiLKKAQEKEKQ---LKEE 1198
Cdd:PTZ00121  1260 ARMAHFARRQAAIKAEEARKADELKKAEEKKKAD-EAKKAEEKKKADEAKKKAEEAKKADEA-KKKAEEAKKKadaAKKK 1337

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1199 LREQKDAYHHLQGQFHEQNKEKENIADQLRQLQCQARESIDRQLPGTGQQEPGPPAPSLEGISLEDTEPASESDLHAAQP 1278
Cdd:PTZ00121  1338 AEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAK 1417

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1279 SPPGETAALQATVSVAQiqaqlkemeveKEELELKVSSIASELAKKSEEvlllqdqineqGLEIQNLKAASVEAQAHTEL 1358
Cdd:PTZ00121  1418 KKADEAKKKAEEKKKAD-----------EAKKKAEEAKKADEAKKKAEE-----------AKKAEEAKKKAEEAKKADEA 1475

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1359 LKQELESSQlkvagLEHLKTLQPELDALHKHMGQKEEEVNYLyGQLSEKEQTLTTVQTEMVEQERliKALHTQLEMQAKE 1438
Cdd:PTZ00121  1476 KKKAEEAKK-----ADEAKKKAEEAKKKADEAKKAAEAKKKA-DEAKKAEEAKKADEAKKAEEAK--KADEAKKAEEKKK 1547

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1439 HEERLKQAQVEICELKKKPTELEEETNAKQQLQRKLQAALISRKEALKENKSLQEQLSSARDAVERLTKSLADVESQVSV 1518
Cdd:PTZ00121  1548 ADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKK 1627

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1519 QNQEKDAVLGKLTILQEERDKliAEMDRFLLENQSLSGSCESLKLALGGLTEDKEKLMEELESVRSSKMAESTEWQEKHK 1598
Cdd:PTZ00121  1628 AEEEKKKVEQLKKKEAEEKKK--AEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAE 1705

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1599 ELQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQELYAKLRSTESDKREREKQLQDAEQEMEEMKEKMRKFAKSKQQki 1678
Cdd:PTZ00121  1706 ELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEE-- 1783

                          730
                   ....*....|....*
gi 1039751015 1679 lELEEENDRLRAEAQ 1693
Cdd:PTZ00121  1784 -ELDEEDEKRRMEVD 1797
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 47-529 1.16e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 54.56  E-value: 1.16e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015   47 ESTQEDALHRLAEAEKLVVELKDIISQKDVQLQQKDEALQEEKKAAENKIKKIKlHAKAKIMSLNKHMEEIktqggaalp 126
Cdd:COG1196    252 EAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIA-RLEERRRELEERLEEL--------- 321

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  127 pEAQAEELSKHNKSSTEEEMEIEKIKHELQEKEKLISSLQAQLDQSEQASQLDKSSAEMEDFVLMKQQLQEKEELISTLQ 206
Cdd:COG1196    322 -EEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAA 400

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  207 TQLSQTQAEQAAQlssmqqvvrEKDARFETQVRLHEDELLQLVTQSDVEtemQQKLRVMQRKLEEHEEALLGRAQVVDLL 286
Cdd:COG1196    401 QLEELEEAEEALL---------ERLERLEEELEELEEALAELEEEEEEE---EEALEEAAEEEAELEEEEEALLELLAEL 468

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  287 QKELTSAEQRNQVLSQQLQLLEAEHNTLKNTMETERQESKTLMEKVELEVAERklsfhnLQEEMHQLQGQLERAGQAQAD 366
Cdd:COG1196    469 LEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRG------LAGAVAVLIGVEAAYEAALEA 542

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  367 LETqySALQQRHKTEMEEKTACILSLQKNEQELQSACAALKEENSKLLQEKHDQAAEsAQAMRQLEDQLQQKSKEISQFV 446
Cdd:COG1196    543 ALA--AALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAI-GAAVDLVASDLREADARYYVLG 619

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  447 NkpnlqkneTASQTSLPDVNNEGDQAVMEETVASLQKRVVELENEKGALLLSSGELEELKAENEKLSSRITLLEAQNRAG 526
Cdd:COG1196    620 D--------TLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEE 691


                   ...
gi 1039751015  527 EAD 529
Cdd:COG1196    692 ELE 694
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1331-1773 1.41e-06

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 54.35  E-value: 1.41e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1331 LQDQINEQGLEIQNL----KAASVEAQAHTEllkQELESSQLKVAGLEHLKTLQPELDALHKHMGQKEEEVNYLYGQLSE 1406
Cdd:pfam15921  417 LRRELDDRNMEVQRLeallKAMKSECQGQME---RQMAAIQGKNESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLES 493

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1407 KEQTLTTVQTEMVEQERLIKALHTQLEMQAKEHEERLKQAQveicelkkkptELEEETNAKQQLQRKLQAALISRKEALK 1486
Cdd:pfam15921  494 SERTVSDLTASLQEKERAIEATNAEITKLRSRVDLKLQELQ-----------HLKNEGDHLRNVQTECEALKLQMAEKDK 562

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1487 ENKSLQEQLSSARDAV---ERLTKSLADVESQVSVQNQEKDAVLGKLTILQEERDKLIAEmdrflLENQSLSGSCESLKL 1563
Cdd:pfam15921  563 VIEILRQQIENMTQLVgqhGRTAGAMQVEKAQLEKEINDRRLELQEFKILKDKKDAKIRE-----LEARVSDLELEKVKL 637

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1564 ALGGltEDKEKLMEELESVRSSKMAESTEWQEKHKELQKEYEVLLQSYENVSNEAERIQHvvesvrqekqELYAKLRSTE 1643
Cdd:pfam15921  638 VNAG--SERLRAVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMETTTN----------KLKMQLKSAQ 705

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1644 SDKREREKQLQDAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEAQPVGGTGESMEALLSSNSSLKEELEKITLEH 1723
Cdd:pfam15921  706 SELEQTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATEK 785

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1724 KTLSKEFEALMAEKDALSEETRNLKLQVEAQVLKQASLEATEKSDEPKDV 1773
Cdd:pfam15921  786 NKMAGELEVLRSQERRLKEKVANMEVALDKASLQFAECQDIIQRQEQESV 835
PTZ00121 PTZ00121
MAEBL; Provisional
 714-1229 6.73e-06

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 52.45  E-value: 6.73e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  714 EKVKEISSLTQLSEEVKESAEEARSTLAAVTEERDQLLYQVKELDVLAELRARVQELEsslaEAEKQRGLDyESQRAQHN 793
Cdd:PTZ00121  1227 EAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELK----KAEEKKKAD-EAKKAEEK 1301

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  794 LLTEQIHSLSIEAKSKD---VKIEALQRELDGVQLQFCEQGTQMKTLQSQLEAKEREVREGTERlrdisQEMEGLSQALS 870
Cdd:PTZ00121  1302 KKADEAKKKAEEAKKADeakKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEK-----AEAAEKKKEEA 1376

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  871 QKELEIAKMDQlllEKQKDVETLQQTIQEKDQQVTELSFSMTEKmvQLNEEKFSLGVEIKT---LKEQLNLLSRTEEATK 947
Cdd:PTZ00121  1377 KKKADAAKKKA---EEKKKADEAKKKAEEDKKKADELKKAAAAK--KKADEAKKKAEEKKKadeAKKKAEEAKKADEAKK 1451

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  948 EQVEESGAGSSLKLGHDESGQEGLQQELELLRKESEQRKRKLQAalinrKELLQKVSQLEEELAKVREDSRKEIPFGENE 1027
Cdd:PTZ00121  1452 KAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEA-----KKKADEAKKAAEAKKKADEAKKAEEAKKADE 1526

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1028 RRKLEEDRENRDDPEEWGTSKWREVEASlkqtiseKEVELEGIRRDLKEKTAAEEELQAVVQRMTRDLQSKTKQIDLLQE 1107
Cdd:PTZ00121  1527 AKKAEEAKKADEAKKAEEKKKADELKKA-------EELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMK 1599

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1108 EVTENQatiqklvtgTMDAGNGGSAAPVKETAASSPPGAggEEHWKPELEGRILDLEKDKTQLQKKLQEALIARKAILKK 1187
Cdd:PTZ00121  1600 LYEEEK---------KMKAEEAKKAEEAKIKAEELKKAE--EEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAK 1668

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|..
gi 1039751015 1188 AQEKEKQLKEELREQKDAYHHLQGQFHEQNKEKENiADQLRQ 1229
Cdd:PTZ00121  1669 KAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKK-AEELKK 1709
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2776-3054 1.68e-05

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 50.71  E-value: 1.68e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2776 ENVLSRLEKLNQQLTSKDEQLLHLSSELESSHNQVQSISKAMTSLQNERDRLWSELEKFRKSEEGKQRaaapsaasspaE 2855
Cdd:COG1196    235 RELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQ-----------D 303

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2856 VQSLKKAMSSLQNDRDRLLKELKNLQQQYLQMSQEMTELRPLKAQLQESQDQTKALQVMEEELRQENLSWQHELRQLRME 2935
Cdd:COG1196    304 IARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEE 383

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2936 KNSWELHERRMKEQFLMAISDKDQQLGHLQSLLRELRSSSQAQILSTQYQRQASPETSASLDGSQKLVYETELLRTQLND 3015
Cdd:COG1196    384 LAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLE 463

                          250       260       270
                   ....*....|....*....|....*....|....*....
gi 1039751015 3016 SLKEIHQKELRIQQLNSKFSQLLEEKNVLSTQLSDASQS 3054
Cdd:COG1196    464 LLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEAD 502
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 2477-3057 4.89e-05

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 49.45  E-value: 4.89e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2477 SAILEKDQLIQDAAAENNKLKEEMRGLRSHM----DDLNSENAKLDAELVQYRRDLNEViaikDSQQKQLLDAQLQQNK- 2551
Cdd:pfam12128  269 SDETLIASRQEERQETSAELNQLLRTLDDQWkekrDELNGELSAADAAVAKDRSELEAL----EDQHGAFLDADIETAAa 344

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2552 ------ELRNECTKLEERLKGLEAEKQSLQMSSDAL-QKEKQGLSKEIKNLQTQLTALQEEGTLG------VYHAQLKAK 2618
Cdd:pfam12128  345 dqeqlpSWQSELENLEERLKALTGKHQDVTAKYNRRrSKIKEQNNRDIAGIKDKLAKIREARDRQlavaedDLQALESEL 424

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2619 EEELQRLNMALSSSQKRTADLEEELVCVQKEATRKVSEIEDQLKK--ELKHLHHDAGIMRNETETA--EERVAELARD-- 2692
Cdd:pfam12128  425 REQLEAGKLEFNEEEYRLKSRLGELKLRLNQATATPELLLQLENFdeRIERAREEQEAANAEVERLqsELRQARKRRDqa 504

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2693 ---LVEMEQKLLTVTKENKDLMAQIqaFGRSMSSLQDSRDHATEELGDLKKKYDASLKELAQLKEWQDSSREGDVLSQAA 2769
Cdd:pfam12128  505 seaLRQASRRLEERQSALDELELQL--FPQAGTLLHFLRKEAPDWEQSIGKVISPELLHRTDLDPEVWDGSVGGELNLYG 582

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2770 FPLSTSENVLSRLEKLNQQLTSKDEQllhLSSELESSHNQVQSISKAMTSLQNERDRLWSELEkfrkseegkqraaapsa 2849
Cdd:pfam12128  583 VKLDLKRIDVPEWAASEEELRERLDK---AEEALQSAREKQAAAEEQLVQANGELEKASREET----------------- 642

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2850 asspaevqslkKAMSSLQNDRDRlLKELKNLQQQYLQMSQEMTELRPLKAQlQESQDQTKALQVMEEELRQENLSWQHEL 2929
Cdd:pfam12128  643 -----------FARTALKNARLD-LRRLFDEKQSEKDKKNKALAERKDSAN-ERLNSLEAQLKQLDKKHQAWLEEQKEQK 709

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2930 RQLRMEKNswelherrmkEQFLMAISDKDQQLGHLQSLLRELRSSSQAQI--LSTQYQRQAspetsASLDGSQKLVYETE 3007
Cdd:pfam12128  710 REARTEKQ----------AYWQVVEGALDAQLALLKAAIAARRSGAKAELkaLETWYKRDL-----ASLGVDPDVIAKLK 774

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1039751015 3008 LLRTQLNDSLKEIHQKELRIQQLNSKF-SQLLEEKNVLSTQLSDASQSLRE 3057
Cdd:pfam12128  775 REIRTLERKIERIAVRRQEVLRYFDWYqETWLQRRPRLATQLSNIERAISE 825
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 153-442 4.53e-04

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 46.21  E-value: 4.53e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  153 HELQEKEKLISSLQAQLDQSEQA-----SQLDKSSAEMEDFVLMKQQLQEKE----ELISTLQTQLSQTQAEQAAQLSSM 223
Cdd:TIGR02169  681 ERLEGLKRELSSLQSELRRIENRldelsQELSDASRKIGEIEKEIEQLEQEEeklkERLEELEEDLSSLEQEIENVKSEL 760

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  224 QQVVREKDARFETQVRLHE-------DELLQLVTQSDVETEMQQKLRVMQRK-LEEHEEALLGRAQVVDLLQKELTSAEQ 295
Cdd:TIGR02169  761 KELEARIEELEEDLHKLEEalndleaRLSHSRIPEIQAELSKLEEEVSRIEArLREIEQKLNRLTLEKEYLEKEIQELQE 840

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  296 RNQVLSQQLQLLEAEHNTLKNTMETERQESKTL----------MEKVELEVAERKLSFHNLQEEMHQLQGQLERAGQAQA 365
Cdd:TIGR02169  841 QRIDLKEQIKSIEKEIENLNGKKEELEEELEELeaalrdlesrLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLS 920

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  366 DLETQYSALQQRHKT------EMEEKTACILSL---QKNEQELQSACAALKEENSKL-------------LQEKHDQAAE 423
Cdd:TIGR02169  921 ELKAKLEALEEELSEiedpkgEDEEIPEEELSLedvQAELQRVEEEIRALEPVNMLAiqeyeevlkrldeLKEKRAKLEE 1000

                          330
                   ....*....|....*....
gi 1039751015  424 SAQAMRQLEDQLQQKSKEI 442
Cdd:TIGR02169 1001 ERKAILERIEEYEKKKREV 1019
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1710-1921 4.79e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.53  E-value: 4.79e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1710 SSLKEELEKITLEHKTLSKEFEALMAEKDALSEETRNLKLQVEA--QVLKQASLEATEKSDEPKDVIEEVTQAVVGKSQE 1787
Cdd:COG4942     23 AEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAAlaRRIRALEQELAALEAELAELEKEIAELRAELEAQ 102

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1788 RDALSDSAKledsEAILMGDGAKPGV---SETFSSHDDIKNYLQQL-DQLKGRIAELEMEKQKDRELSQALENEKNALLT 1863
Cdd:COG4942    103 KEELAELLR----ALYRLGRQPPLALllsPEDFLDAVRRLQYLKYLaPARREQAEELRADLAELAALRAELEAERAELEA 178

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1039751015 1864 QISAKDSELKLLEEEVTKRTTLNQQIQEELcrvtKLKETAEEEKDDLEERLMNQLAEL 1921
Cdd:COG4942    179 LLAELEEERAALEALKAERQKLLARLEKEL----AELAAELAELQQEAEELEALIARL 232
PRK11281 PRK11281
mechanosensitive channel MscK;
154-375 1.33e-03

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 44.52  E-value: 1.33e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  154 ELQEKEKLISSLQAQLDQSEQASQLDKSSAEMEDFVLMKQ-QLQEKEE-------LISTLQTQLSQTQAEQAAQLSSMQQ 225
Cdd:PRK11281    95 KLRQAQAELEALKDDNDEETRETLSTLSLRQLESRLAQTLdQLQNAQNdlaeynsQLVSLQTQPERAQAALYANSQRLQQ 174

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  226 VVREKDARFETQVRLHEDELLQLVTQS---DVETEMQQKL----RVMQRKLEEHEEALLGRAQV----VDLLQ-----KE 289
Cdd:PRK11281   175 IRNLLKGGKVGGKALRPSQRVLLQAEQallNAQNDLQRKSlegnTQLQDLLQKQRDYLTARIQRlehqLQLLQeainsKR 254

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  290 LTSAEQRNQVLSQQLQLLEAEHNTL-KNTMETERQESKTLMEKVELEVAerkLSFHNLQeemhqLQGQLERAGQAQADLE 368
Cdd:PRK11281   255 LTLSEKTVQEAQSQDEAARIQANPLvAQELEINLQLSQRLLKATEKLNT---LTQQNLR-----VKNWLDRLTQSERNIK 326


                   ....*..
gi 1039751015  369 TQYSALQ 375
Cdd:PRK11281   327 EQISVLK 333
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
2551-3036 2.61e-03

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 43.51  E-value: 2.61e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2551 KELRNECTKLEERLKGLEAEKQSLQMSSDALQKEKQGLSKEIKNLQTQLTALQEE-GTLGVYHAQLKAKEEELQRLNMAL 2629
Cdd:PRK03918   168 GEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREElEKLEKEVKELEELKEEIEELEKEL 247

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2630 SSSQKRTADLEEELVCVQKEATRKVSEIEDqLKKELKHLhhdagimrNETETAEERVAELARDLVEMEQKLLTVTKENKD 2709
Cdd:PRK03918   248 ESLEGSKRKLEEKIRELEERIEELKKEIEE-LEEKVKEL--------KELKEKAEEYIKLSEFYEEYLDELREIEKRLSR 318

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2710 LMAQIQAFGRSMSSLQDSRdhatEELGDLKKKYDASLKELAQLKEWQDSSREGDVLSQAAFPLSTSENVLSrLEKLNQQL 2789
Cdd:PRK03918   319 LEEEINGIEERIKELEEKE----ERLEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLT-PEKLEKEL 393

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2790 TSKDEQLLHLSSELESshnqvqsISKAMTSLQNERDRLWSELEKFRKSE--------EGKQRAAAPSAASSPAEVQSLKK 2861
Cdd:PRK03918   394 EELEKAKEEIEEEISK-------ITARIGELKKEIKELKKAIEELKKAKgkcpvcgrELTEEHRKELLEEYTAELKRIEK 466

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2862 AMSSLQNDRDRLLKELKNLQQQyLQMSQEMTELRPLKAQLQESQDQTKALQVME--------EELRQENLSWQHELRQLR 2933
Cdd:PRK03918   467 ELKEIEEKERKLRKELRELEKV-LKKESELIKLKELAEQLKELEEKLKKYNLEElekkaeeyEKLKEKLIKLKGEIKSLK 545

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2934 MEKNSWELHERRmKEQFLMAISDKDQQLGHLQSLLRELRSSSQAQI------LSTQYQR-----QASPETSASLDGSQKL 3002
Cdd:PRK03918   546 KELEKLEELKKK-LAELEKKLDELEEELAELLKELEELGFESVEELeerlkeLEPFYNEylelkDAEKELEREEKELKKL 624

                          490       500       510
                   ....*....|....*....|....*....|....
gi 1039751015 3003 VYETELLRTQLNDSLKEIHQKELRIQQLNSKFSQ 3036
Cdd:PRK03918   625 EEELDKAFEELAETEKRLEELRKELEELEKKYSE 658
 
Name Accession Description Interval E-value
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1830-2754 3.30e-20

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 99.36  E-value: 3.30e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1830 LDQLKGRIAELE-----MEKQKDR-ELSQALENEKNALLTQISAKDselklLEEEVTKRTTLNQQIQEelcrVTKLKETA 1903
Cdd:TIGR02168  188 LDRLEDILNELErqlksLERQAEKaERYKELKAELRELELALLVLR-----LEELREELEELQEELKE----AEEELEEL 258

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1904 EEEKDDLEErlmnQLAELNGSIGNYYQDVTDAQIKNEQLESEMRNLQRCVSELEEEKQQLVKEKTKVESEIRKeymekiq 1983
Cdd:TIGR02168  259 TAELQELEE----KLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEE------- 327

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1984 gaqkgpaNKSHAKELQELLREKQQEVKQLQKDCIRYLERISALEKTVKALEFVHTESQKDLDVTKGNLAQAVEHRKKAQA 2063
Cdd:TIGR02168  328 -------LESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNN 400

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2064 ELSSFKILLDDTQSEAARVLADNLKLKKELQSNKesiksqikqkdedlLRRLEQAEEKHRKEKKNMQEKLDALHREKAHV 2143
Cdd:TIGR02168  401 EIERLEARLERLEDRRERLQQEIEELLKKLEEAE--------------LKELQAELEELEEELEELQEELERLEEALEEL 466

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2144 EETLAEIQVSLTRKDQEMKELQGSLDStlaqlaafTKSMSSLQDDRDRVIDEAKKWERRFGDAIQTKEE--EVRLKEENC 2221
Cdd:TIGR02168  467 REELEEAEQALDAAERELAQLQARLDS--------LERLQENLEGFSEGVKALLKNQSGLSGILGVLSEliSVDEGYEAA 538

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2222 IALKDQLRQMAIHMEELKITVSRLEHDKEIWESKAqTELQHHQKAYDKLQEENKELTSQLEDARQLYHDSKNELTKLESE 2301
Cdd:TIGR02168  539 IEAALGGRLQAVVVENLNAAKKAIAFLKQNELGRV-TFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKA 617

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2302 LKSLKDQ---TTDLNNSLEKCKehENNLEGIIKQQEADIQNCKFsceqletdlaasreltsrlhdeinakeqkIISLLSG 2378
Cdd:TIGR02168  618 LSYLLGGvlvVDDLDNALELAK--KLRPGYRIVTLDGDLVRPGG-----------------------------VITGGSA 666

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2379 KEEAIQLAVEelhqqhsKEIKELENLLSQEEEENVALEEENKRALEKTNQLTEALEAIKKESFEQKAQLDSFVKSMSSLq 2458
Cdd:TIGR02168  667 KTNSSILERR-------REIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARL- 738

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2459 ddrdrivsdyRQLEERHLSAILEKDQLIQDAAAENNKLKEEMRGLRSHMDDLNSENAKLDAELVQYRRDLNEVIAIKDSQ 2538
Cdd:TIGR02168  739 ----------EAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDEL 808

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2539 QKQLldaqlqqnKELRNECTKLEERLKGLEAEKQSLQMSSDALQKEKQGLSKEIKNLQTQLTALQEEGTlgVYHAQLKAK 2618
Cdd:TIGR02168  809 RAEL--------TLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIE--ELESELEAL 878

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2619 EEELQRLNMALSSSQKRTADLEEELvcvqKEATRKVSEIEDQ---LKKELKHLHHDAGIMRNETETAEERVAELARDLVE 2695
Cdd:TIGR02168  879 LNERASLEEALALLRSELEELSEEL----RELESKRSELRREleeLREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLE 954

                          890       900       910       920       930       940
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2696 M-EQKLLTVTKENKDLMAQIQAFGRSMSSLQDSRDHATEELGDLKKKYDASLKELAQLKE 2754
Cdd:TIGR02168  955 EaEALENKIEDDEEEARRRLKRLENKIKELGPVNLAAIEEYEELKERYDFLTAQKEDLTE 1014
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2100-2912 3.33e-19

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 95.89  E-value: 3.33e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2100 IKSQIKQKDEDLL-RRLEQAEEKHR---KEKKNMQEKLDALHREKAHVEETLAEIQVSLTRKDQEMKELQGSLDSTLAQL 2175
Cdd:TIGR02168  218 LKAELRELELALLvLRLEELREELEelqEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEI 297

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2176 AAFTKSMSSLQDDRDRVIDEAKKWERRFGDAIQTKEEevrlKEENCIALKDQLRQMAIHMEELKITVSRLEHDKEIWESK 2255
Cdd:TIGR02168  298 SRLEQQKQILRERLANLERQLEELEAQLEELESKLDE----LAEELAELEEKLEELKEELESLEAELEELEAELEELESR 373

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2256 aqtelqhhqkaydklqeeNKELTSQLEDARQLYHDSKNELTKLESELKSLKDQTTDLNNSLEKckEHENNLEGIIKQQEA 2335
Cdd:TIGR02168  374 ------------------LEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRER--LQQEIEELLKKLEEA 433

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2336 DIQNCKFSCEQLETDLAasrELTSRLhDEINAKEQKIISLLSGKEEAIQLAVEELhQQHSKEIKELENLLSQEEEENVAL 2415
Cdd:TIGR02168  434 ELKELQAELEELEEELE---ELQEEL-ERLEEALEELREELEEAEQALDAAEREL-AQLQARLDSLERLQENLEGFSEGV 508

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2416 EEENKRALEKTNQLTEALEAIKKESFEQKAQLDSFVKSMSSLQDDRD----RIVSDYRQLEERHLSAILEKDQLIQDAAA 2491
Cdd:TIGR02168  509 KALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGRLQAVVVENLnaakKAIAFLKQNELGRVTFLPLDSIKGTEIQG 588

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2492 ENNKLKEEMRGLRSHMDDLNSENAKLDAeLVQYRrdLNEVIAIKDsqqkqlLDAQLQQNKELRnectkLEERLKGLEAE- 2570
Cdd:TIGR02168  589 NDREILKNIEGFLGVAKDLVKFDPKLRK-ALSYL--LGGVLVVDD------LDNALELAKKLR-----PGYRIVTLDGDl 654

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2571 ---KQSLQMSSDALQKEKQGLSKEIKNLQTQLTALQEEGTLGvyHAQLKAKEEELQRLNMALSSSQKRTADLEEELVCVQ 2647
Cdd:TIGR02168  655 vrpGGVITGGSAKTNSSILERRREIEELEEKIEELEEKIAEL--EKALAELRKELEELEEELEQLRKELEELSRQISALR 732

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2648 KEATRKVSEIEdQLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLTVTKENKDLMAQIQAFGRSMSSLQds 2727
Cdd:TIGR02168  733 KDLARLEAEVE-QLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELR-- 809

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2728 rdhatEELGDLKKKYDASLKELAQL-KEWQDSSREGDVLSQaafplsTSENVLSRLEKLNQQLTSKDEQLLHLSSELESS 2806
Cdd:TIGR02168  810 -----AELTLLNEEAANLRERLESLeRRIAATERRLEDLEE------QIEELSEDIESLAAEIEELEELIEELESELEAL 878

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2807 HNQVQSISKAMTSLQNERDrlwsELEKFRKSEEGKQRAAAPSAASSPAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQ 2886
Cdd:TIGR02168  879 LNERASLEEALALLRSELE----ELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLE 954

                          810       820
                   ....*....|....*....|....*.
gi 1039751015 2887 MSQEMTELRPlkAQLQESQDQTKALQ 2912
Cdd:TIGR02168  955 EAEALENKIE--DDEEEARRRLKRLE 978
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 309-1037 6.83e-19

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 94.74  E-value: 6.83e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  309 AEHNTLKNTMETERQESKTLMEKVELEVAERKLSFHNLQEEMHQLQGQLERAGQAQADLETQYSALQQRHK---TEMEEK 385
Cdd:TIGR02168  242 EELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLAnleRQLEEL 321

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  386 TACILSLQKNEQELQSACAALKEEN----------SKLLQEKHDQAAESAQAMRQLEDQLQQKSKEISQFVNKPNLQKNE 455
Cdd:TIGR02168  322 EAQLEELESKLDELAEELAELEEKLeelkeeleslEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNE 401

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  456 tasqtslpdvnnegdQAVMEETVASLQKRVVELENEKGALL---------LSSGELEELKAENEKLSSRitLLEAQNRAG 526
Cdd:TIGR02168  402 ---------------IERLEARLERLEDRRERLQQEIEELLkkleeaelkELQAELEELEEELEELQEE--LERLEEALE 464

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  527 EADGTVCEVSTAGTTLLNRSDSSpeENGQAVLENTFsQKHKELSVLLVEMKEAQEEIAFLKSQL-QGKRPEGDYE----- 600
Cdd:TIGR02168  465 ELREELEEAEQALDAAERELAQL--QARLDSLERLQ-ENLEGFSEGVKALLKNQSGLSGILGVLsELISVDEGYEaaiea 541

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  601 ---------VLDRREVQLMESEGPPSVTAGDVLCAPSDESSGPAAEEEQAGMKDRHRaSEAGPLNDagMELSSPKLDGV- 670
Cdd:TIGR02168  542 alggrlqavVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIE-GFLGVAKD--LVKFDPKLRKAl 618

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  671 DKSLAVSHVCQCHQGELERLKTqvLELETSLHTAE------------ETYKRNLS--EKVKEISSLTQLSEEVKESAEEA 736
Cdd:TIGR02168  619 SYLLGGVLVVDDLDNALELAKK--LRPGYRIVTLDgdlvrpggvitgGSAKTNSSilERRREIEELEEKIEELEEKIAEL 696

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  737 RSTLAAVTEERDQLlyqvkeLDVLAELRARVQELESSLAEAEKqrglDYESQRAQHNLLTEQIHSLSIEAKSKDVKIEAL 816
Cdd:TIGR02168  697 EKALAELRKELEEL------EEELEQLRKELEELSRQISALRK----DLARLEAEVEQLEERIAQLSKELTELEAEIEEL 766

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  817 QRELDGVQLQFCEQGTQMKTLQSQLEAKEREVREGTERLRDISQEMEGLSQALSQKELEIAKMDQLLLEKQKDVETLQQT 896
Cdd:TIGR02168  767 EERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQ 846

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  897 IQEKDQQVTELSFSMTEKMVQLNEEKfslgveiKTLKEQLNLLSRTEEATKEQVEESGAgSSLKLGHDESGQEGLQQELE 976
Cdd:TIGR02168  847 IEELSEDIESLAAEIEELEELIEELE-------SELEALLNERASLEEALALLRSELEE-LSEELRELESKRSELRRELE 918

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1039751015  977 LLRKESEQRKRKLQAALINRKELLQKVS---QLEEELAKVREDSRKEIPFG-ENERRKLEEDREN 1037
Cdd:TIGR02168  919 ELREKLAQLELRLEGLEVRIDNLQERLSeeySLTLEEAEALENKIEDDEEEaRRRLKRLENKIKE 983
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 730-1635 6.24e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 91.66  E-value: 6.24e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  730 KESAEEARSTLAAVTEERDQLLyqvkelDVLAELRARVQELESSLAEAEKQRGLDYESQRAQHNLLTEQIHSLsieaksk 809
Cdd:TIGR02168  171 KERRKETERKLERTRENLDRLE------DILNELERQLKSLERQAEKAERYKELKAELRELELALLVLRLEEL------- 237

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  810 DVKIEALQRELDGVQLQFCEQGTQMKTLQSQLEAKEREVREGTERLRDISQEMEGLSQALSQKELEIAKMDQLLLEKQKD 889
Cdd:TIGR02168  238 REELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQ 317

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  890 VETLQQTIQEKDQQVTElsfsmtekmvqLNEEKFSLGVEIKTLKEQLNLLSRTEEATKEQVEESgagsslklghdESGQE 969
Cdd:TIGR02168  318 LEELEAQLEELESKLDE-----------LAEELAELEEKLEELKEELESLEAELEELEAELEEL-----------ESRLE 375

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  970 GLQQELELLRKESEQRKRKLQAALINRKELLQKVSQLEEELAkvredsrkeipfgenerRKLEEDRENRDDPEEWGTSKW 1049
Cdd:TIGR02168  376 ELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRE-----------------RLQQEIEELLKKLEEAELKEL 438

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1050 REVEASLKQTISEKEVELEGIRRDLKEKTAAEEELQAVVQRMTRDLQSKTKQIDLLqEEVTENQATIQKLVTGTMDAGNG 1129
Cdd:TIGR02168  439 QAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSL-ERLQENLEGFSEGVKALLKNQSG 517

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1130 GSA-APVKETAASSPPGaggeehWKPELE----GRILDLEKDKTQLQKKLQEALiarkailkKAQEKEKQLKEELREQKD 1204
Cdd:TIGR02168  518 LSGiLGVLSELISVDEG------YEAAIEaalgGRLQAVVVENLNAAKKAIAFL--------KQNELGRVTFLPLDSIKG 583

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1205 AyhHLQGQFHEQNKEKENIADQLRQLqcqarESIDRQLPGTGQqepgppaPSLEGISLEDTepaSESDLHAAQPSPPGET 1284
Cdd:TIGR02168  584 T--EIQGNDREILKNIEGFLGVAKDL-----VKFDPKLRKALS-------YLLGGVLVVDD---LDNALELAKKLRPGYR 646

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1285 AALQATVSVAQIQAQLKEMEVEKEELELKVssiaSELAKKSEEVLLLQDQINEQGLEIQNLKAASVEAQAHTELLKQELE 1364
Cdd:TIGR02168  647 IVTLDGDLVRPGGVITGGSAKTNSSILERR----REIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELE 722

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1365 SSQLKVAGL-EHLKTLQPELDALHKHMGQKEEEVNYLYGQLSEKEQTLTTVQTEMVEQERLIKalhtQLEMQAKEHEERL 1443
Cdd:TIGR02168  723 ELSRQISALrKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIE----ELEAQIEQLKEEL 798

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1444 KQAQVEICELKKKPTELEEE----TNAKQQLQRKLQAALISRKEALKENKSLQEQLSSARDAVERLTKSLADVESQVSVQ 1519
Cdd:TIGR02168  799 KALREALDELRAELTLLNEEaanlRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEAL 878

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1520 NQEKDAVLGKLTILQEERDKLIAEMDRFLLENQSLSGSCESLKLALGGLTEDKEKLMEELESVRSSKMAestewqekhkE 1599
Cdd:TIGR02168  879 LNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSE----------E 948

                          890       900       910
                   ....*....|....*....|....*....|....*.
gi 1039751015 1600 LQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQEL 1635
Cdd:TIGR02168  949 YSLTLEEAEALENKIEDDEEEARRRLKRLENKIKEL 984
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1331-2164 2.37e-17

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 89.73  E-value: 2.37e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1331 LQDQINEQGLEIQNLKAASVEAQAHTELlKQELESSQLKVAGLEhLKTLQPELDALHKHMGQKEEEVNYLYGQLSEKEQT 1410
Cdd:TIGR02168  191 LEDILNELERQLKSLERQAEKAERYKEL-KAELRELELALLVLR-LEELREELEELQEELKEAEEELEELTAELQELEEK 268

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1411 LTTVQTEMVEQERLIKALHTQL----------EMQAKEHEERL-------KQAQVEICELKKKPTELEEETNAKQQLQRK 1473
Cdd:TIGR02168  269 LEELRLEVSELEEEIEELQKELyalaneisrlEQQKQILRERLanlerqlEELEAQLEELESKLDELAEELAELEEKLEE 348

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1474 LQAALISRKEALKE-----------NKSLQEQLSSARDAVERLTKSLADVESQVSVQNQEKDAVLGKLTILQEERDKLIA 1542
Cdd:TIGR02168  349 LKEELESLEAELEEleaeleelesrLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLK 428

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1543 EMDRflLENQSLSGSCESLKLALggltedkeklmeelesvrsskmaestewqekhKELQKEYEVLLQSYENVSNEAERIQ 1622
Cdd:TIGR02168  429 KLEE--AELKELQAELEELEEEL--------------------------------EELQEELERLEEALEELREELEEAE 474

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1623 HVVESVRQEKQELYAKLRSTESDKREREKQLQDAEQEMEEMKEKMRKFAKSKQQkiLELEEENDRLRAEAqpvggTGESM 1702
Cdd:TIGR02168  475 QALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSEL--ISVDEGYEAAIEAA-----LGGRL 547

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1703 EALLSSNSSLKEELEKITLEHKTLSKEFEALMAEKDALSEETRNLKLQVEAQVLKQASLEATEKSDEPKDVIEEVTQAVV 1782
Cdd:TIGR02168  548 QAVVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLV 627

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1783 GKSQErDALSDSAKLEDSEAI------------LMGDGAKPGVSETFSSHDDIKNYLQQLDQLKGRIAELEMEKQKDREL 1850
Cdd:TIGR02168  628 VDDLD-NALELAKKLRPGYRIvtldgdlvrpggVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKE 706

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1851 SQALENE-------KNALLTQISAKDSELKLLEEEVTKRTTLNQQIQEELCRVTKLKETAEEEKDDLEErlmnQLAELNG 1923
Cdd:TIGR02168  707 LEELEEEleqlrkeLEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEE----ELAEAEA 782

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1924 SIGNYYQDVTDAQIKNEQLESEMRNLQRCVSELEEEKQQLVKEKTKVESEIRKEYMEKIQGAQKGPANKSHAKELQELLR 2003
Cdd:TIGR02168  783 EIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIE 862

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2004 EKQQEVKQLQKDCIRYLERISALEKTVKALEFVHTESQKDLDVT-------KGNLAQAVEHRKKAQAELSSFKILLDDTQ 2076
Cdd:TIGR02168  863 ELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELeskrselRRELEELREKLAQLELRLEGLEVRIDNLQ 942

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2077 SEAARVLADNLKLKKELQSNKESIKSQIKQKDEDLLRRLEQ-------AEEKHRKEKknmqEKLDALHREKAHVEETLAE 2149
Cdd:TIGR02168  943 ERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKElgpvnlaAIEEYEELK----ERYDFLTAQKEDLTEAKET 1018

                          890
                   ....*....|....*
gi 1039751015 2150 IQVSLTRKDQEMKEL 2164
Cdd:TIGR02168 1019 LEEAIEEIDREARER 1033
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1826-2595 8.75e-17

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 88.19  E-value: 8.75e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1826 YLQQLDQLKGRIAELEMEKQKDRELSQALENEKNALLTQISAKDSELKLLEEEVTKRTTLNQQIQEELCRVTKLKETAEE 1905
Cdd:TIGR02168  230 LVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRE 309

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1906 EKDDLEerlmNQLAELNGSIgnyyqdvtdaqiknEQLESEMRNLQRCVSELEEEKQQLVKEKTKVESEIRKEYMEKiqga 1985
Cdd:TIGR02168  310 RLANLE----RQLEELEAQL--------------EELESKLDELAEELAELEEKLEELKEELESLEAELEELEAEL---- 367

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1986 qkgPANKSHAKELQELLREKQQEVKQLQKDCIRYLERISALEKTVKALEfvhTESQKDLDVTKGNLAQAVEHRKKA-QAE 2064
Cdd:TIGR02168  368 ---EELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLE---DRRERLQQEIEELLKKLEEAELKElQAE 441

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2065 LSSFKILLDDTQSEAARVLADNLKLKKELQSNKESIKS------QIKQKDEDLLRRLEQAEEKHRKEKKNMQEKL----- 2133
Cdd:TIGR02168  442 LEELEEELEELQEELERLEEALEELREELEEAEQALDAaerelaQLQARLDSLERLQENLEGFSEGVKALLKNQSglsgi 521

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2134 -----DALHREK---AHVEETLAE-IQVSLTRKDQEMKELQGSLDSTLAQLAAF------------------TKSMSSLQ 2186
Cdd:TIGR02168  522 lgvlsELISVDEgyeAAIEAALGGrLQAVVVENLNAAKKAIAFLKQNELGRVTFlpldsikgteiqgndreiLKNIEGFL 601

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2187 DDRDRVIDEAKKWERRFG---------DAIQTKEEEVRL--KEENCIALKDQL--RQMAIHMEELKITVSRLEHDKEIWE 2253
Cdd:TIGR02168  602 GVAKDLVKFDPKLRKALSyllggvlvvDDLDNALELAKKlrPGYRIVTLDGDLvrPGGVITGGSAKTNSSILERRREIEE 681

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2254 SKAQTElqhhqkaydKLQEENKELTSQLEDARQLYHDSKNELTKLESELKSLKDQTTDLNNSLEKCKEHENNLEGIIKQQ 2333
Cdd:TIGR02168  682 LEEKIE---------ELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQL 752

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2334 EADIQNCKFSCEQLETDLAASRELTSRLHDEINAKEQKIISLLS--GKEEAIQLAVEELHQQHSKEIKELENLLSQEEEE 2411
Cdd:TIGR02168  753 SKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEelKALREALDELRAELTLLNEEAANLRERLESLERR 832

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2412 NVALEEENKRALEKTNQLTEALEAIKKESFEQKAQLDSFVKSMSSLQDDRDRIvsdyRQLEERHLSAILEKDQLIQDAAA 2491
Cdd:TIGR02168  833 IAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASL----EEALALLRSELEELSEELRELES 908

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2492 ENNKLKEEMRGLRSHMDDLNSENAKLDAEL--------VQYRRDLNEVIAIKDSQQKQLLDAQlQQNKELRNECTKL--- 2560
Cdd:TIGR02168  909 KRSELRRELEELREKLAQLELRLEGLEVRIdnlqerlsEEYSLTLEEAEALENKIEDDEEEAR-RRLKRLENKIKELgpv 987

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|....*.
gi 1039751015 2561 -----------EERLKGLEAEKQSLQMSSDALQKEKQGLSKEIKNL 2595
Cdd:TIGR02168  988 nlaaieeyeelKERYDFLTAQKEDLTEAKETLEEAIEEIDREARER 1033
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1411-2314 8.87e-16

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 84.73  E-value: 8.87e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1411 LTTVQTEMVEQERLIKALHTQLEMQAKEHEERLKqaqVEICELKKKPTELEEETNAKQQLQRKLQAALISRKEALKENKS 1490
Cdd:TIGR02169  179 LEEVEENIERLDLIIDEKRQQLERLRREREKAER---YQALLKEKREYEGYELLKEKEALERQKEAIERQLASLEEELEK 255

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1491 LQEQLSSARDAVERLTKSLADVESQVS-VQNQEKDAVLGKLTILQEERDKLIAEMDRFLLENQSLSGSCESLKLALGGLT 1569
Cdd:TIGR02169  256 LTEEISELEKRLEEIEQLLEELNKKIKdLGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLL 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1570 EDKEKLMEELESVRsskmAESTEWQEKHKELQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQELYAKLrstESDKRER 1649
Cdd:TIGR02169  336 AEIEELEREIEEER----KRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREI---NELKREL 408

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1650 EKqLQDAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEAQPVGGTGESMEALLSSNSS----LKEELEKITLEHKT 1725
Cdd:TIGR02169  409 DR-LQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQelydLKEEYDRVEKELSK 487

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1726 LSKEFEALMAEKDALSEETRNLKLQVEaqvlkqasleatEKSDEPKDVIEEVTQAVVGKSQERDALSDSAkledseailm 1805
Cdd:TIGR02169  488 LQRELAEAEAQARASEERVRGGRAVEE------------VLKASIQGVHGTVAQLGSVGERYATAIEVAA---------- 545

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1806 GDGAKPGVSETfssHDDIKNYLQQLDQLK-GRIAELEMEKQKDRELSQALENEKNALltqisakDSELKLLEEEVTKRTT 1884
Cdd:TIGR02169  546 GNRLNNVVVED---DAVAKEAIELLKRRKaGRATFLPLNKMRDERRDLSILSEDGVI-------GFAVDLVEFDPKYEPA 615

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1885 LNQQIQEelcrvTKLKETAEEEKDDLEERLMNQLA----ELNGSIGNYYQDVTDAQIKNEQLESEMRNLQRCVSELEEEK 1960
Cdd:TIGR02169  616 FKYVFGD-----TLVVEDIEAARRLMGKYRMVTLEgelfEKSGAMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKREL 690

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1961 QQLVKEKTKVESEIrKEYMEKIQGAQKgpankshakelqeLLREKQQEVKQLQKDCIRYLERISALEKTVKALEFVHTES 2040
Cdd:TIGR02169  691 SSLQSELRRIENRL-DELSQELSDASR-------------KIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENV 756

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2041 QKDLDVTKGNLAQAVEHRKKAQAELSSFKILLDDTQSEAARVLADnlKLKKELQSNkESIKSQIKQKDEDLLRRLEQAEe 2120
Cdd:TIGR02169  757 KSELKELEARIEELEEDLHKLEEALNDLEARLSHSRIPEIQAELS--KLEEEVSRI-EARLREIEQKLNRLTLEKEYLE- 832

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2121 khrKEKKNMQEKLDALHREKAHVEETLAEIQVSLTRKDQEMKELQgsldstlAQLAAFTKSMSSLQDDRDRVIDEAKKWE 2200
Cdd:TIGR02169  833 ---KEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELE-------AALRDLESRLGDLKKERDELEAQLRELE 902

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2201 RRfgdaIQTKEEEVRLKEENciaLKDQLRQMAIHMEELKITVSRLEHDKEIWES-----KAQTELQHHQKAYDKLQEENK 2275
Cdd:TIGR02169  903 RK----IEELEAQIEKKRKR---LSELKAKLEALEEELSEIEDPKGEDEEIPEEelsleDVQAELQRVEEEIRALEPVNM 975

                          890       900       910
                   ....*....|....*....|....*....|....*....
gi 1039751015 2276 ELTSQLEDARQLYHDSKNELTKLESELKSLKDQTTDLNN 2314
Cdd:TIGR02169  976 LAIQEYEEVLKRLDELKEKRAKLEEERKAILERIEEYEK 1014
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1823-2664 1.10e-15

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 84.35  E-value: 1.10e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1823 IKNYLQQLDQLKGRIAELEMEKQKDRELSQA----LENEKNALLTQISAKDSELKLLEEEVTKRTTLNQQIQEELCRVTK 1898
Cdd:TIGR02169  193 IDEKRQQLERLRREREKAERYQALLKEKREYegyeLLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQ 272

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1899 LKETAEEEKDDLEERLMNQLaelngsignyyqdvtdaQIKNEQLESEMRNLQRCVSELEEEKQQLVKEKTKVESEIRKEy 1978
Cdd:TIGR02169  273 LLEELNKKIKDLGEEEQLRV-----------------KEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKL- 334

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1979 mekiqgaqkgpanKSHAKELQELLREKQQEVKQLQkdcirylERISALEKTVKALEFVHTESQKDLDVTKGNLAQAVEHR 2058
Cdd:TIGR02169  335 -------------LAEIEELEREIEEERKRRDKLT-------EEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKL 394

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2059 KKAQAELSSFKILLDDTQSEAARVLADNLKLKKELqsnkESIKSQIKQKDEDLLRRLEQAEEKHRKEKKNmQEKLDALHR 2138
Cdd:TIGR02169  395 EKLKREINELKRELDRLQEELQRLSEELADLNAAI----AGIEAKINELEEEKEDKALEIKKQEWKLEQL-AADLSKYEQ 469

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2139 EKAHVEETLAEIQVSLTRKDQEMKELQGSLDSTLAQLAAFTKSMSSLQDDRDRV---IDEAKKWERRFGDAIQTK----- 2210
Cdd:TIGR02169  470 ELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVhgtVAQLGSVGERYATAIEVAagnrl 549

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2211 -----EEEVRLKEenCIALkdqLRQMAI---------HMEELKITVSRLEHDKEIWESKAQTELQHHQKAYDKLQEENKE 2276
Cdd:TIGR02169  550 nnvvvEDDAVAKE--AIEL---LKRRKAgratflplnKMRDERRDLSILSEDGVIGFAVDLVEFDPKYEPAFKYVFGDTL 624

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2277 LTSQLEDARQLYhdSKNELTKLESELKSLKDQTTDLNNSlekckehENNLEGIIKQQEADIQNCKFSCEQLETDLAASRE 2356
Cdd:TIGR02169  625 VVEDIEAARRLM--GKYRMVTLEGELFEKSGAMTGGSRA-------PRGGILFSRSEPAELQRLRERLEGLKRELSSLQS 695

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2357 LTSRLHDEINAKEQKiISLLSGKEEAIQLAVEELHQQHSK---EIKELENLLSQEEEENVALEEENKRALEKTNQLTEAL 2433
Cdd:TIGR02169  696 ELRRIENRLDELSQE-LSDASRKIGEIEKEIEQLEQEEEKlkeRLEELEEDLSSLEQEIENVKSELKELEARIEELEEDL 774

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2434 EAIKKESFEQKA-----QLDSFVKSMSSLQDDRDRIVSDYRQLEERHLSAILEKDQL---IQDAAAENNKLKEEMRGLRS 2505
Cdd:TIGR02169  775 HKLEEALNDLEArlshsRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLekeIQELQEQRIDLKEQIKSIEK 854

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2506 HMDDLNSENAKLDAELVQYRRDLNEVIAIKDSQQKQLldaqlqqnKELRNECTKLEERLKGLEAEKQSLQMSSDALQKEK 2585
Cdd:TIGR02169  855 EIENLNGKKEELEEELEELEAALRDLESRLGDLKKER--------DELEAQLRELERKIEELEAQIEKKRKRLSELKAKL 926

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2586 QGLSKEIKNLQTQLTALQEEG----TLGVYHAQLKAKEEELQRL---NMA----LSSSQKRTADLEEELVCVQKEATRKV 2654
Cdd:TIGR02169  927 EALEEELSEIEDPKGEDEEIPeeelSLEDVQAELQRVEEEIRALepvNMLaiqeYEEVLKRLDELKEKRAKLEEERKAIL 1006

                          890
                   ....*....|..
gi 1039751015 2655 SEIE--DQLKKE 2664
Cdd:TIGR02169 1007 ERIEeyEKKKRE 1018
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1481-2382 5.56e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 82.03  E-value: 5.56e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1481 RKEALKenkslqeQLSSARDAVERLTKSLADVESQV-SVQNQEKDAVlgKLTILQEERDKLiaEMDRFLLENQSLSGSCE 1559
Cdd:TIGR02168  174 RKETER-------KLERTRENLDRLEDILNELERQLkSLERQAEKAE--RYKELKAELREL--ELALLVLRLEELREELE 242

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1560 SLKLALggltEDKEKLMEELESVRSSKMAESTEWQEKHKELQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQELYAKL 1639
Cdd:TIGR02168  243 ELQEEL----KEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQL 318

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1640 RSTESDKREREKQLQDAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEAQPVGGTGESMEALLSSNSSLKEELEKI 1719
Cdd:TIGR02168  319 EELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASL 398

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1720 TLEHKTLSKEFEALMAEKDALSEETRNLKLQVEAQVLKQASLEATEKSDEPKDVIEEVTQAVVGKSQERDALS------D 1793
Cdd:TIGR02168  399 NNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEeaeqalD 478

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1794 SAKLEDSEAILMGDGAKPGVSETFSSHDDIKNYLQQLDQLKGRIAELEMEKQKDRELSQALENEKNALLTQISAKDSELK 1873
Cdd:TIGR02168  479 AAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGRLQAVVVENLNAA 558

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1874 LLEEEVTKrttlnqqiQEELCRVTKLKETAEEEkDDLEERLMNQLAELNGSIGnYYQDVTDAQIKNEQLESEMRNLQRCV 1953
Cdd:TIGR02168  559 KKAIAFLK--------QNELGRVTFLPLDSIKG-TEIQGNDREILKNIEGFLG-VAKDLVKFDPKLRKALSYLLGGVLVV 628

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1954 SELEEEKQQLVKEKTKVESEIRKEYMEKIQGAQKGPANKSHA---------KELQELLREKQQEVKQLQKDCIRYLERIS 2024
Cdd:TIGR02168  629 DDLDNALELAKKLRPGYRIVTLDGDLVRPGGVITGGSAKTNSsilerrreiEELEEKIEELEEKIAELEKALAELRKELE 708

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2025 ALEKTVKALEFVHTESQKDLDVTKGNLAQAVEHRKKAQAELSSfkilLDDTQSEAARVLADNLKLKKELQSNKESIKSQI 2104
Cdd:TIGR02168  709 ELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQ----LSKELTELEAEIEELEERLEEAEEELAEAEAEI 784

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2105 KQKDEDLLRRLEQAeEKHRKEKKNMQEKLDALHREKAHVEETLAEIQVSLTRKDQEMKELQGSLDSTLAQLAAFTKSMSS 2184
Cdd:TIGR02168  785 EELEAQIEQLKEEL-KALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEE 863

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2185 LQDDRDRVIDEAKKWerrfgdaiqtkEEEVRLKEENCIALKDQLRQMAIHMEELKITVSRLEHDKEiwesKAQTELQHHQ 2264
Cdd:TIGR02168  864 LEELIEELESELEAL-----------LNERASLEEALALLRSELEELSEELRELESKRSELRRELE----ELREKLAQLE 928

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2265 KAYDKLQEENKELTSQL--------EDARQLYHDSKNELTKLESELKSLKDQTTDLNN----SLEKCKEHENNLEGIIKQ 2332
Cdd:TIGR02168  929 LRLEGLEVRIDNLQERLseeysltlEEAEALENKIEDDEEEARRRLKRLENKIKELGPvnlaAIEEYEELKERYDFLTAQ 1008

                          890       900       910       920       930
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1039751015 2333 QEaDIQNCKFSCEQLETDLaaSRELTSRLHD---EINAKEQKIISLLSGKEEA 2382
Cdd:TIGR02168 1009 KE-DLTEAKETLEEAIEEI--DREARERFKDtfdQVNENFQRVFPKLFGGGEA 1058
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 758-1400 5.94e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 78.44  E-value: 5.94e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  758 DVLAELRARVQELESSLAEAEKQRGLDYESQRAQHNLLTEQIHSLSIEAKSKDVKIEALQRELdgvqlqfceqgtqmKTL 837
Cdd:COG1196    193 DILGELERQLEPLERQAEKAERYRELKEELKELEAELLLLKLRELEAELEELEAELEELEAEL--------------EEL 258

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  838 QSQLEAKEREVREGTERLRDISQEMEGLSQALSQKELEIAKMDQLLLEKQKDVETLQQTIQEKDQQVTELsfsmTEKMVQ 917
Cdd:COG1196    259 EAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAEL----EEELEE 334

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  918 LNEEKFSLGVEIKTLKEQLNLLSRTEEATKEQVEEsgagsslklghDESGQEGLQQELELLRKESEQRKRKLQAALINRK 997
Cdd:COG1196    335 LEEELEELEEELEEAEEELEEAEAELAEAEEALLE-----------AEAELAEAEEELEELAEELLEALRAAAELAAQLE 403

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  998 ELLQKVSQLEEELAKVREDSRKEipfgENERRKLEEDRENRddpeewgtskwREVEASLKQTISEKEVELEGIRRDLKEK 1077
Cdd:COG1196    404 ELEEAEEALLERLERLEEELEEL----EEALAELEEEEEEE-----------EEALEEAAEEEAELEEEEEALLELLAEL 468

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1078 TAAEEELQAVVQRMTRDLQSKTKQIDLLQEEVTEnqatiqklvtgtMDAGNGGSAAPVKETAASSPPGAGGEEHWKPELE 1157
Cdd:COG1196    469 LEEAALLEAALAELLEELAEAAARLLLLLEAEAD------------YEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAY 536

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1158 GRILDLEKDKTQLQKKLQEALIARKAILKKAQEKEKQLKEELREQKDAYHHLQGQFHEQNKEKENIADQLRQLQCQARES 1237
Cdd:COG1196    537 EAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYY 616

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1238 IDRQLPGTGQQEPGPPAPSLEGISLEDTEPASESDLHAAQPSPPGETAALQATVSVAQIQAQLKEMEVEKEELELKVSSI 1317
Cdd:COG1196    617 VLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELE 696

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1318 ASELAKKSEEVLLLQDQINEQGLEIQNLKAASVEAQAHTELLKQELESSQLKVAGLEHLKTLQPELDALHKHMGQKEEEV 1397
Cdd:COG1196    697 EALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREI 776


                   ...
gi 1039751015 1398 NYL 1400
Cdd:COG1196    777 EAL 779
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1403-1976 8.77e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 78.05  E-value: 8.77e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1403 QLSEKEQTLTTVQTEMVEQERLIKALHTQLEMQAKEHEERLKQAQVEICELKKKPTELEE----ETNAKQQLQRKLQAAL 1478
Cdd:COG1196    243 ELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQdiarLEERRRELEERLEELE 322

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1479 ISRKEALKENKSLQEQLSSARDAVERLTKSLADVESQVSVQNQEKDAVLGKLTILQEERDKLIAEMDRFLLENQSLSGSC 1558
Cdd:COG1196    323 EELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQL 402

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1559 ESLKLALGGLTEDKEKLMEELESVRSSKMAESTEWQEKHKELQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQELYAK 1638
Cdd:COG1196    403 EELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAEL 482

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1639 LRSTESDKREREKQLQDAEQEMEEMKEKMRKFAKSKQQKILEL--EEENDRLRAEAQPVGGTGESMEALLSSNSSLKEEL 1716
Cdd:COG1196    483 LEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAvaVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAA 562

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1717 EKITLEHKTLSKEFEAL-MAEKDALSEETRNLKLQVEAQVLKQASLEATEKSDEPKDVIEEVTQAVVGKSQERDALSDSA 1795
Cdd:COG1196    563 IEYLKAAKAGRATFLPLdKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTL 642

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1796 KLEDSEAILMGDGAKPGVSETfsshddiknylqqLDQLKGRIAELEMEKQKDRELSQALENEKNALLTQISAKDSELKLL 1875
Cdd:COG1196    643 AGRLREVTLEGEGGSAGGSLT-------------GGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEEREL 709

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1876 EEEVTKRTTLNQQIQEELCRVTKLKETAEEEKDDLEERLMNQLAELNGSIgnyyQDVTDAQIKNEQLESEMRNLQRcV-- 1953
Cdd:COG1196    710 AEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEP----PDLEELERELERLEREIEALGP-Vnl 784

                          570       580
                   ....*....|....*....|....*....
gi 1039751015 1954 ------SELEEEKQQLVKEKTKVESEIRK 1976
Cdd:COG1196    785 laieeyEELEERYDFLSEQREDLEEARET 813
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 684-1258 1.21e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 74.20  E-value: 1.21e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  684 QGELERLKTQVLELETSLHTAEETYKRNLSEKVKEISSLTQLSEEVKESAEEARSTLAAVTEERDQLLYQVKELDVLAEL 763
Cdd:COG1196    238 EAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEER 317

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  764 RARVQELESSLAEAEKQRGLDYESQRAQHNLLTEQIHSLSIEAKSKDVKIEALQRELDGVQLQFCEQGTQMKTLQSQLEA 843
Cdd:COG1196    318 LEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAE 397

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  844 KEREVREGTERLRDISQEMEGLSQALSQKELEIAKMDQLLLEKQKDVETLQQTIQEKDQQVTELsfsmTEKMVQLNEEKF 923
Cdd:COG1196    398 LAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEAL----LELLAELLEEAA 473

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  924 SLGVEIKTLKEQLNLLSRTEEATKE-QVEESGAGSSLKLGHDESGQEGLQQELELLRKESEQRKRKLQAALInrkELLQK 1002
Cdd:COG1196    474 LLEAALAELLEELAEAAARLLLLLEaEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALA---AALQN 550

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1003 VSQLEEELAKVREDSRKEIPFGENERRKLEEDRENRDDPeewgtskwrevEASLKQTISEKEVELEGIRRDLKEKTAAEE 1082
Cdd:COG1196    551 IVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALA-----------AALARGAIGAAVDLVASDLREADARYYVLG 619

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1083 ELQAVVQRMTRDLQSKTKQIDLLQEEVTEnqatiqklVTGTMDAGNGGSAapvketaassppgaggeehwkpelEGRILD 1162
Cdd:COG1196    620 DTLLGRTLVAARLEAALRRAVTLAGRLRE--------VTLEGEGGSAGGS------------------------LTGGSR 667

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1163 LEKDKTQLQKKLQEALIARKAILKKAQEKEKQLKEELREQKDAYHHLQGQFHEQNKEKENIADQLRQLQCQARESIDRQL 1242
Cdd:COG1196    668 RELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEEL 747

                          570
                   ....*....|....*.
gi 1039751015 1243 PGTGQQEPGPPAPSLE 1258
Cdd:COG1196    748 LEEEALEELPEPPDLE 763
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 51-926 1.92e-12

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 73.55  E-value: 1.92e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015   51 EDALHRLAEAEKLVVELKDIISQKDVQLqqkdEALQEEKKAAE------NKIKKIKLH-AKAKIMSLNKHMEEIKTQgga 123
Cdd:TIGR02168  175 KETERKLERTRENLDRLEDILNELERQL----KSLERQAEKAErykelkAELRELELAlLVLRLEELREELEELQEE--- 247

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  124 alpPEAQAEELSKHNKSSTEEEMEIEKIKHELQEKEKLISSLQAQLDQSeqasqldksSAEMEDFVLMKQQLQEKEELIS 203
Cdd:TIGR02168  248 ---LKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYAL---------ANEISRLEQQKQILRERLANLE 315

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  204 TLQTQLSQTQAEQAAQLSSMQQVVREKDARFETQVRLHEDELLQLvtqsdveTEMQQKLRVMQRKLEEHEEALLGRAQVV 283
Cdd:TIGR02168  316 RQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAEL-------EELEAELEELESRLEELEEQLETLRSKV 388

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  284 DLLQKELTSAEQRNQVLSQQLQLLEAEHNTLKNTMETERQE-SKTLMEKVELEVAERKLSFHNLQEEMHQLQGQLERAGQ 362
Cdd:TIGR02168  389 AQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKlEEAELKELQAELEELEEELEELQEELERLEEALEELRE 468

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  363 AQADLETQYSALQQrhktEMEEKTACILSLQKNEQELQSACAALKE--ENSKLLQEKHDQAAESAQAMRQLEDQLQQKSK 440
Cdd:TIGR02168  469 ELEEAEQALDAAER----ELAQLQARLDSLERLQENLEGFSEGVKAllKNQSGLSGILGVLSELISVDEGYEAAIEAALG 544

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  441 EISQFVNKPNLQKNETASQTSLPdvNNEGDQAVMEETVAS---LQKRVVELENEKGALLLSSGELEELKAENEKLSSRI- 516
Cdd:TIGR02168  545 GRLQAVVVENLNAAKKAIAFLKQ--NELGRVTFLPLDSIKgteIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLl 622

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  517 -------TLLEAQNRAGEADGTVCEVSTAGTTLLNRSDSSPEENGQavlENTFSQKHKELSVLLVEMKEAQEEIAFLKSQ 589
Cdd:TIGR02168  623 ggvlvvdDLDNALELAKKLRPGYRIVTLDGDLVRPGGVITGGSAKT---NSSILERRREIEELEEKIEELEEKIAELEKA 699

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  590 LQGKrpegdyevldRREVQLMESEGPPSVTAGDVLCAPSDESSGPAAEEEQAGMKDRHRASEAgplndagmelsspkldg 669
Cdd:TIGR02168  700 LAEL----------RKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQL----------------- 752

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  670 vdkslavshvcqchQGELERLKTQVLELETSLHTAEETYKRNLSEKVKEISSLTQLSEEVKESAEEARSTLAAVTEERDQ 749
Cdd:TIGR02168  753 --------------SKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEE 818

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  750 llyqvkeldvLAELRARVQELESSLAEAEKQrgldYESQRAQHNLLTEQIHSLSIEAKSKDVKIEALQRELDGVQLQFCE 829
Cdd:TIGR02168  819 ----------AANLRERLESLERRIAATERR----LEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERAS 884

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  830 QGTQMKTLQSQLEAKEREVREGTERLRDISQEMEGLSQALSQKELEIAKMDQLLLEKQK----DVETLQQTIQEKDQQVT 905
Cdd:TIGR02168  885 LEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQErlseEYSLTLEEAEALENKIE 964

                          890       900
                   ....*....|....*....|.
gi 1039751015  906 ELSFSMTEKMVQLNEEKFSLG 926
Cdd:TIGR02168  965 DDEEEARRRLKRLENKIKELG 985
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1995-2595 2.20e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 73.43  E-value: 2.20e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1995 AKELQELLREKQQEVKQLQKDcirylerisALEKTVKALEFVHTESQKDLDVTKGNLAQAVEHRKKAQAELSSFKILLDD 2074
Cdd:COG1196    215 YRELKEELKELEAELLLLKLR---------ELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEE 285

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2075 TQSEAARVLADNLKLKKELQSNKESIKSQikqkdEDLLRRLEQAEEKHRKEKKNMQEKLDALHREKAHVEETLAEIQVSL 2154
Cdd:COG1196    286 AQAEEYELLAELARLEQDIARLEERRREL-----EERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAEL 360

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2155 TRKDQEMKELQGSLDSTLAQLAAFTKSMSSLQDDRDRvideakkwerrfgdaIQTKEEEVRLKEENCIALKDQLRQMAIH 2234
Cdd:COG1196    361 AEAEEALLEAEAELAEAEEELEELAEELLEALRAAAE---------------LAAQLEELEEAEEALLERLERLEEELEE 425

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2235 MEELKITVSRLEHDKEIWESKAQTELQHHQKAYDKLQEENKELTSQLEDARQLYHDSKNELTKLESELKSLKDQTTDLNN 2314
Cdd:COG1196    426 LEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEG 505

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2315 SLEKCKE-HENNLEGIIKQQEADIQNCKFSCEQLETDLAASRELTSRLHDEINAKE--QKIISLLSGKEEAIQLAVEELH 2391
Cdd:COG1196    506 FLEGVKAaLLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAaiEYLKAAKAGRATFLPLDKIRAR 585

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2392 QQHSKEIKELENLLSQEEEENVALEEENKRALEKTNQLTEALEAIKKES-FEQKAQLDSFVKSMSSLQDDRDRIVSDYRQ 2470
Cdd:COG1196    586 AALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAaLRRAVTLAGRLREVTLEGEGGSAGGSLTGG 665

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2471 LEERHLSAILEKDQLIQDAAAENNKLKEEMRGLRSHMDDLNSENAKLDAELVQYRRDLNEVIAIKDSQQKQLLDAQLQQN 2550
Cdd:COG1196    666 SRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEE 745

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*
gi 1039751015 2551 KELRNEctkleerlkglEAEKQSLQMSSDALQKEKQGLSKEIKNL 2595
Cdd:COG1196    746 ELLEEE-----------ALEELPEPPDLEELERELERLEREIEAL 779
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 2102-2920 2.38e-12

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 73.56  E-value: 2.38e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2102 SQIKQKDEDLLRRLEQAEEKHRKEKKNMQEK---LDALHREKAHVEETLAeiqVSLTRKDQEMKELQGSLDSTLAQLAAF 2178
Cdd:TIGR02169  166 AEFDRKKEKALEELEEVEENIERLDLIIDEKrqqLERLRREREKAERYQA---LLKEKREYEGYELLKEKEALERQKEAI 242

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2179 TKSMSSLQDDRDRVIDEAKKWERRFGDAIQTKEEEVR----LKEENCIALKDQLRQMAIHMEELKITVSRLEHDKEiwes 2254
Cdd:TIGR02169  243 ERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKkikdLGEEEQLRVKEKIGELEAEIASLERSIAEKERELE---- 318

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2255 KAQTELQHHQKAYDKLQEENKELTSQLEDARQlyhdsknELTKLESELKSLKDQTTDLNNSLEkckehennlegiikqqe 2334
Cdd:TIGR02169  319 DAEERLAKLEAEIDKLLAEIEELEREIEEERK-------RRDKLTEEYAELKEELEDLRAELE----------------- 374

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2335 adiqnckfsceQLETDLAASRELTSRLHDEINAKEQKIISLLSGKEEAIqlaveELHQQHSKEIKELENLLsqeeeenva 2414
Cdd:TIGR02169  375 -----------EVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQ-----EELQRLSEELADLNAAI--------- 429

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2415 leeenKRALEKTNQLTEALEAIKKESFEQKAQLDSFVKSMSSLQDDRDRIVSDYRQLEERhlsaILEKDQLIQDAAAENN 2494
Cdd:TIGR02169  430 -----AGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKE----LSKLQRELAEAEAQAR 500

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2495 KLKEEMRGLRSHMDDLNSENA---KLDAELVQYRRD------------LNEVIAIKDSQQKQ----LLDAQLQQNKELRN 2555
Cdd:TIGR02169  501 ASEERVRGGRAVEEVLKASIQgvhGTVAQLGSVGERyataievaagnrLNNVVVEDDAVAKEaielLKRRKAGRATFLPL 580

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2556 ECTKLEERLKGLEAEKQSLQMSSDALQKEKQ---------GLSKEIKNLQT--------QLTALQEE----------GTL 2608
Cdd:TIGR02169  581 NKMRDERRDLSILSEDGVIGFAVDLVEFDPKyepafkyvfGDTLVVEDIEAarrlmgkyRMVTLEGElfeksgamtgGSR 660

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2609 GVYHAQLKAKE--EELQRLNMALSSSQKRTADLEEELVCVQKEATRKVSEIEDqLKKELKHLHHDAGIMRNETETAEERV 2686
Cdd:TIGR02169  661 APRGGILFSRSepAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSD-ASRKIGEIEKEIEQLEQEEEKLKERL 739

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2687 AELARDLVEMEQKLLTVTKENKDLMAQIQAFGRSMSSLQdsrdhatEELGDLKKKYDASlkelaqlkEWQDSSREgdvls 2766
Cdd:TIGR02169  740 EELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLE-------EALNDLEARLSHS--------RIPEIQAE----- 799

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2767 qaafplstsenvlsrLEKLNQQLTSKDEQLLHLSSELESSHNQVQSISKAMTSLQNERDRLWSELEKFRKSEE---GKQR 2843
Cdd:TIGR02169  800 ---------------LSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIEnlnGKKE 864

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1039751015 2844 AAAPSAASSPAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQMSQEMTELRPLKAQLQEsqdqtkALQVMEEELRQ 2920
Cdd:TIGR02169  865 ELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKA------KLEALEEELSE 935
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1599-2381 4.05e-12

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 72.79  E-value: 4.05e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1599 ELQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQELyaklrSTESDKREREKQLQDaeqemeeMKEKMRKFAKSKQQKI 1678
Cdd:TIGR02169  167 EFDRKKEKALEELEEVEENIERLDLIIDEKRQQLERL-----RREREKAERYQALLK-------EKREYEGYELLKEKEA 234

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1679 LEleeendrlraeaqpvggtgESMEALLSSNSSLKEELEKITLEHKTLSKEFEALMAEKDAL--------SEETRNLKLQ 1750
Cdd:TIGR02169  235 LE-------------------RQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELnkkikdlgEEEQLRVKEK 295

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1751 VEAQVLKQASLEAT--EKSDEPKDVIEEVTQAVVGKSQERDALSDSAKLEDSEAILmgdgaKPGVSETFSSHDDIKNYL- 1827
Cdd:TIGR02169  296 IGELEAEIASLERSiaEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKR-----RDKLTEEYAELKEELEDLr 370

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1828 QQLDQLKGRIAELEMEKQKDRELSQALENEKNALLTQISAKDSELKLLEEEVTKrttLNQQIQEELCRVTKLKETAEEEK 1907
Cdd:TIGR02169  371 AELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELAD---LNAAIAGIEAKINELEEEKEDKA 447

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1908 DDLEErLMNQLAELNGSIGNYYQDVTDAQIKNEQLESEMRNLQRCVSELEEEKQQLVKEKT--KVESEIRKEYMEKIQG- 1984
Cdd:TIGR02169  448 LEIKK-QEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRggRAVEEVLKASIQGVHGt 526

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1985 -AQKGPANKSHAKELQELLREKQQEV----KQLQKDCIRYLERISALEKTVKAL-EFVHTESQKDLDVTKGNLAQAVEHR 2058
Cdd:TIGR02169  527 vAQLGSVGERYATAIEVAAGNRLNNVvvedDAVAKEAIELLKRRKAGRATFLPLnKMRDERRDLSILSEDGVIGFAVDLV 606

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2059 KKAQAELSSFKILLDDT----QSEAARVLADNLK---LKKEL---------QSNKESIKSQIKQKDEDLLRRLEQAEEKH 2122
Cdd:TIGR02169  607 EFDPKYEPAFKYVFGDTlvveDIEAARRLMGKYRmvtLEGELfeksgamtgGSRAPRGGILFSRSEPAELQRLRERLEGL 686

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2123 RKEKKNMQEKLDALHREKAHVEETLAEIQVSLTRKDQEMKELQGSLDSTLAQLAAFTKSMSSLQDDRDRVIDEAKKWERR 2202
Cdd:TIGR02169  687 KRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEAR 766

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2203 FGDaIQTKEEEVRLKEENCIA--LKDQLRQMAIHMEELKITVSRLE---HDKEIWESKAQTELQHHQKAYDKLQEENKEL 2277
Cdd:TIGR02169  767 IEE-LEEDLHKLEEALNDLEArlSHSRIPEIQAELSKLEEEVSRIEarlREIEQKLNRLTLEKEYLEKEIQELQEQRIDL 845

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2278 TSQLEDARQLYHDSKNELTKLESELKSLKDQTTDLNNSLEKCKEHENNLEGIIKQQEADIQNCKFSCEQLETDLAASREL 2357
Cdd:TIGR02169  846 KEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAK 925

                          810       820
                   ....*....|....*....|....
gi 1039751015 2358 TSRLHDEINAKEQKIISLLSGKEE 2381
Cdd:TIGR02169  926 LEALEEELSEIEDPKGEDEEIPEE 949
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1823-2352 4.14e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 72.66  E-value: 4.14e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1823 IKNYLQQLDQLKGRIAELEMEKQKDRELSQALENEKNALLTQISAKDSELKLLEEEVTKRTTLNQQIQEELCRVTKLKET 1902
Cdd:COG1196    234 LRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRE 313

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1903 AEEEKDDLEErlmnQLAELNGSIGNYYQDVTDAQIKNEQLESEMRNLQRCVSELEEEKQQLVKEKTKVESEIRKEYMEKI 1982
Cdd:COG1196    314 LEERLEELEE----ELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELL 389

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1983 qgaqkgpankshakELQELLREKQQEVKQLQKDCIRYLERISALEKTVKALEFVHTESQKDLDVTKGNLAQAVEHRKKAQ 2062
Cdd:COG1196    390 --------------EALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELE 455

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2063 AELSSFKILLDDTQSEAARVLADNLKLKKELQSNKESIKSQIKQKDEDLLrRLEQAEEKHRKEKKNMQEKLDALHREKAH 2142
Cdd:COG1196    456 EEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEG-FLEGVKAALLLAGLRGLAGAVAVLIGVEA 534

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2143 VEETLAE------IQVSLTRKDQEMKELQGSLDSTLAQLAAF-------------TKSMSSLQDDRDRVIDEAKKWERRF 2203
Cdd:COG1196    535 AYEAALEaalaaaLQNIVVEDDEVAAAAIEYLKAAKAGRATFlpldkiraraalaAALARGAIGAAVDLVASDLREADAR 614

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2204 GDAIQTKEEEVRLKEENCIA-------LKDQLRQMAIHMEELKITVSRLEHDKEIWESKAQTELQHHQKAYDKLQEENKE 2276
Cdd:COG1196    615 YYVLGDTLLGRTLVAARLEAalrravtLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELE 694

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1039751015 2277 LTSQLEDARQLYHDSKNELTKLESELKSLKDQTTDLNNSLEKCKEHENNLEGIIKQQEADIQNCKFSCEQLETDLA 2352
Cdd:COG1196    695 LEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELE 770
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2059-2624 5.56e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 72.28  E-value: 5.56e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2059 KKAQAELSSFKI-LLDDTQSEAARVLADNLKLKKELQSNKESIKSQIKQKDEDLLRrLEQAEEKHRKEKKNMQEKLDALH 2137
Cdd:COG1196    223 KELEAELLLLKLrELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEE-LELELEEAQAEEYELLAELARLE 301

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2138 REKAHVEETLAEIQVSLTRKDQEMKELQGSLDSTLAQLAAFTKSMSSLQDDRDRVIDEAKKWERRFGDAIQTKEEEVRLK 2217
Cdd:COG1196    302 QDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEEL 381

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2218 EENCIALKDQLRQMAIHMEELKITVSRLEhdkeiwesKAQTELQHHQKAYDKLQEENKELTSQLEDARQLYHDSKNELTK 2297
Cdd:COG1196    382 EELAEELLEALRAAAELAAQLEELEEAEE--------ALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAE 453

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2298 LESELKSLKDQTTDLNNSLEKCKEHENNLEGIIKQQEAdiqnckfsceQLETDLAASRELTSRLHDEINAKEQKIISLLS 2377
Cdd:COG1196    454 LEEEEEALLELLAELLEEAALLEAALAELLEELAEAAA----------RLLLLLEAEADYEGFLEGVKAALLLAGLRGLA 523

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2378 GKEEAIQLAVEELhqqhSKEIKELENLLSQEEEENVALEEENKRALEKTNQLTEA----LEAIKKESFEQKAQLDSFVKS 2453
Cdd:COG1196    524 GAVAVLIGVEAAY----EAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRAtflpLDKIRARAALAAALARGAIGA 599

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2454 MSSLQDDRDRIVSDYRQLEERHLSAILEKDQLIQDAAAENNKLKEEMRGLRSHMDDLNSENAKLDAELVQYRRDLNEVIA 2533
Cdd:COG1196    600 AVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEA 679

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2534 IKDSQQKQLLDAQLQQNKELRNEctkLEERLKGLEAEKQSLQMSSDALQKEKQGLSKEIKNLQTQLTALQEEGTLGVYHA 2613
Cdd:COG1196    680 ELEELAERLAEEELELEEALLAE---EEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEEL 756

                          570
                   ....*....|.
gi 1039751015 2614 QLKAKEEELQR 2624
Cdd:COG1196    757 PEPPDLEELER 767
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1420-2013 7.29e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 71.89  E-value: 7.29e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1420 EQERLIKALHTQLEMQAKEHEERLKQAQVEicelkkkptELEEETNAKQQLQRKLQAALISRKEALKEnksLQEQLSSAR 1499
Cdd:COG1196    220 EELKELEAELLLLKLRELEAELEELEAELE---------ELEAELEELEAELAELEAELEELRLELEE---LELELEEAQ 287

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1500 DAVERLTKSLADVESQVSVQNQEKDAvlgkltiLQEERDKLIAEMDRfllenqslsgsceslklalggLTEDKEKLMEEL 1579
Cdd:COG1196    288 AEEYELLAELARLEQDIARLEERRRE-------LEERLEELEEELAE---------------------LEEELEELEEEL 339

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1580 EsvrsskmaestEWQEKHKELQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQELYAKLRSTESDKREREKQLQDAEQE 1659
Cdd:COG1196    340 E-----------ELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEA 408

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1660 MEEMKEKMRKFAKSKQQKILELEEENDRLRAEAQPVggtgESMEALLSSNSSLKEELEKITLEHKTLSKEFEALMAEKDA 1739
Cdd:COG1196    409 EEALLERLERLEEELEELEEALAELEEEEEEEEEAL----EEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLE 484

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1740 LSEETRNLKLQVEAQVLKQASLEATEKSDEPKDVIEEVTQAVvgksqeRDALSDSAKLEDSEAILMGDGAKPGVSETFSS 1819
Cdd:COG1196    485 ELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAV------AVLIGVEAAYEAALEAALAAALQNIVVEDDEV 558

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1820 HDDIKNYLQQldQLKGRIAELEMEKQKDRELSQALEnEKNALLTQISAKDSELKLLEEevtkRTTLNQQIQEELCRVTKL 1899
Cdd:COG1196    559 AAAAIEYLKA--AKAGRATFLPLDKIRARAALAAAL-ARGAIGAAVDLVASDLREADA----RYYVLGDTLLGRTLVAAR 631

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1900 KETAEEEKDDLEERLmnQLAELNGSIGNYYQDVTDAQIKNEQLESEMRNLQRCVSELEEEKQQLVKEKTKVESEIRKEYM 1979
Cdd:COG1196    632 LEAALRRAVTLAGRL--REVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEEREL 709

                          570       580       590
                   ....*....|....*....|....*....|....
gi 1039751015 1980 EKIQGAQKGPANKSHAKELQELLREKQQEVKQLQ 2013
Cdd:COG1196    710 AEAEEERLEEELEEEALEEQLEAEREELLEELLE 743
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1570-2443 9.66e-12

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 71.25  E-value: 9.66e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1570 EDKEKLMEELESVRSSKMAESTEWQEKHKELQKeyevllqsYENVSNEAERIQHVVESVRQ-EKQELYAKLRSTESDKRE 1648
Cdd:TIGR02169  170 RKKEKALEELEEVEENIERLDLIIDEKRQQLER--------LRREREKAERYQALLKEKREyEGYELLKEKEALERQKEA 241

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1649 REKQLQDAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEaqpvgGTGESMEallssnssLKEELEKITLEHKTLSK 1728
Cdd:TIGR02169  242 IERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDL-----GEEEQLR--------VKEKIGELEAEIASLER 308

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1729 EFEALMAEKDALSEETRNLKLQVEAQVLKQASLEatEKSDEPKDVIEEVTQAVVGKSQERDALSDSAKLEDSEAilmgdg 1808
Cdd:TIGR02169  309 SIAEKERELEDAEERLAKLEAEIDKLLAEIEELE--REIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEF------ 380

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1809 akpgvSETFSSHDDIKnylQQLDQLKGRIAELEMEKQKDRELSQALENEKNALLTQISAKDSELKLLEEEVTKRTTLNQQ 1888
Cdd:TIGR02169  381 -----AETRDELKDYR---EKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKK 452

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1889 IQEELCRVTKLKETAEEEKDDLEERLmnqlaelngsignyyqdvtdaqiknEQLESEMRNLQRCVSELEEEKQQLVKEKT 1968
Cdd:TIGR02169  453 QEWKLEQLAADLSKYEQELYDLKEEY-------------------------DRVEKELSKLQRELAEAEAQARASEERVR 507

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1969 --KVESEIRKEYMEKIQG--AQKGPANKSHAKELQELLREKQQEV----KQLQKDCIRYLERISALEKTVKAL-EFVHTE 2039
Cdd:TIGR02169  508 ggRAVEEVLKASIQGVHGtvAQLGSVGERYATAIEVAAGNRLNNVvvedDAVAKEAIELLKRRKAGRATFLPLnKMRDER 587

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2040 SQKDLDVTKGNLAQAVEHRKKAQAELSSFKILLDDT----QSEAARVLADNLK---LKKEL---------QSNKESIKSQ 2103
Cdd:TIGR02169  588 RDLSILSEDGVIGFAVDLVEFDPKYEPAFKYVFGDTlvveDIEAARRLMGKYRmvtLEGELfeksgamtgGSRAPRGGIL 667

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2104 IKQKDEDLLRRLEQAEEKHRKEKKNMQEKLDALHREKAHVEETLAEIQVSLTRKDQEMKELQGSLDSTLAQLAAFTKSMS 2183
Cdd:TIGR02169  668 FSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLS 747

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2184 SLQDDRDRVIDEAKKWERRFGDaIQTKEEEVRLKEENCIA--LKDQLRQMAIHMEELKITVSRLE---HDKEIWESKAQT 2258
Cdd:TIGR02169  748 SLEQEIENVKSELKELEARIEE-LEEDLHKLEEALNDLEArlSHSRIPEIQAELSKLEEEVSRIEarlREIEQKLNRLTL 826

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2259 ELQHHQKAYDKLQEENKELTSQLEDARQLYHDSKNELTKLESELKSLKDQTTDLNNSLEKCKEHENNLEGIIKQQEADIQ 2338
Cdd:TIGR02169  827 EKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIE 906

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2339 NCKFSCEQLETDLAASRELTSRLHDEINAKEQKIISLLSGKEEA-----IQLAVEELHQQHSK----------EIKELEN 2403
Cdd:TIGR02169  907 ELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEElsledVQAELQRVEEEIRAlepvnmlaiqEYEEVLK 986

                          890       900       910       920
                   ....*....|....*....|....*....|....*....|
gi 1039751015 2404 LLSQEEEENVALEEENKRALEKTNQLTEALEAIKKESFEQ 2443
Cdd:TIGR02169  987 RLDELKEKRAKLEEERKAILERIEEYEKKKREVFMEAFEA 1026
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2255-3056 2.83e-11

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 70.09  E-value: 2.83e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2255 KAQTELQHHQKAYDKLQEENKELTSQLE------DARQLYHDSKNELTKLESELksLKDQTTDLNNSLEKCKEHENNLEG 2328
Cdd:TIGR02168  176 ETERKLERTRENLDRLEDILNELERQLKslerqaEKAERYKELKAELRELELAL--LVLRLEELREELEELQEELKEAEE 253

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2329 IIKQQEADIQNCKfscEQLETDLAASRELTSRLhDEINAKEQKIISLLSGKEEAIQLAVEELHQQHsKEIKELENLLSQE 2408
Cdd:TIGR02168  254 ELEELTAELQELE---EKLEELRLEVSELEEEI-EELQKELYALANEISRLEQQKQILRERLANLE-RQLEELEAQLEEL 328

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2409 EEENVALEEENKRALEKTNQLTEALEAIKKESFEQKAQLDSFVKSMSSLQDDRDRIVSDYRQLEERHLSA---ILEKDQL 2485
Cdd:TIGR02168  329 ESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLnneIERLEAR 408

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2486 IQDAAAENNKLKEEMRGLRSHMDDlnsenakldAELVQYRRDLNEVIAIKDSQQKQLLDAQlQQNKELRNECTKLEERLK 2565
Cdd:TIGR02168  409 LERLEDRRERLQQEIEELLKKLEE---------AELKELQAELEELEEELEELQEELERLE-EALEELREELEEAEQALD 478

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2566 GLEAEKQSLQMSSDALQK---EKQGLSKEIKNLQtqLTALQEEGTLGVYHAQLKAKEEELQRLNMALSSS--QKRTADLE 2640
Cdd:TIGR02168  479 AAERELAQLQARLDSLERlqeNLEGFSEGVKALL--KNQSGLSGILGVLSELISVDEGYEAAIEAALGGRlqAVVVENLN 556

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2641 EELVCVQ---KEATRKVS----------EIEDQLKKELKHLHHDAGIMRNETETAE----------------ERVAELAR 2691
Cdd:TIGR02168  557 AAKKAIAflkQNELGRVTflpldsikgtEIQGNDREILKNIEGFLGVAKDLVKFDPklrkalsyllggvlvvDDLDNALE 636

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2692 DLVEMEQKLLTVTKENKDLMAQ-IQAFGR-----SMSSLQDSRDHATEELGDLKKKYDASLKELAQLKEWQDSSREgdVL 2765
Cdd:TIGR02168  637 LAKKLRPGYRIVTLDGDLVRPGgVITGGSaktnsSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEE--EL 714

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2766 SQAAFPLSTSENVLSRLEKLNQQLTSKDEQLLHLSSELESSHNQVQSISKAMTSLQNERDRLWSELEKFRKSEEGKQRAA 2845
Cdd:TIGR02168  715 EQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQL 794

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2846 APSAASSPAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQMSQEMTELRPLKAQLQESQDQTkALQVMEEELRQENLSW 2925
Cdd:TIGR02168  795 KEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESL-AAEIEELEELIEELES 873

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2926 QHELRQLRMEKNSWELHERRMKEQFLMA-ISDKDQQLGHLQSLLRELRSS--------SQAQILSTQYQRQASPETSASL 2996
Cdd:TIGR02168  874 ELEALLNERASLEEALALLRSELEELSEeLRELESKRSELRRELEELREKlaqlelrlEGLEVRIDNLQERLSEEYSLTL 953

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1039751015 2997 DGSQKLVYETELLRTQLNDSLKEIHQKELRIQQLN----SKFSQLLEEKNVLSTQLSDASQSLR 3056
Cdd:TIGR02168  954 EEAEALENKIEDDEEEARRRLKRLENKIKELGPVNlaaiEEYEELKERYDFLTAQKEDLTEAKE 1017
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 261-1084 3.12e-11

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 69.71  E-value: 3.12e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  261 KLRVMQRKLEEHEEALLGRAQVVDLLQKELTSAEQRNQVLSQQLQLLEAEHNTLKNTMETERQESKTLMEKVELEVAERK 340
Cdd:TIGR02169  178 ELEEVEENIERLDLIIDEKRQQLERLRREREKAERYQALLKEKREYEGYELLKEKEALERQKEAIERQLASLEEELEKLT 257

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  341 LSFHNLQEEMHQLQGQLEragQAQADLETQYSALQQRHKTEMEEKTACILSLQKNEQELQSACAALKEENSKLLQEKHDQ 420
Cdd:TIGR02169  258 EEISELEKRLEEIEQLLE---ELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKL 334

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  421 AAESAQAMRQLEDQLQQKSKEISQFVNkpnLQKNETASQTSLPDVNNEGDQAVMEetVASLQKRVVELENEKGALLlssG 500
Cdd:TIGR02169  335 LAEIEELEREIEEERKRRDKLTEEYAE---LKEELEDLRAELEEVDKEFAETRDE--LKDYREKLEKLKREINELK---R 406

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  501 ELEELKAENEKLSSRITLLEAQNRAGEADgtVCEVSTAGTTLLNRSDSSPEENGQAV-----LENTFSQKHKELSVLLVE 575
Cdd:TIGR02169  407 ELDRLQEELQRLSEELADLNAAIAGIEAK--INELEEEKEDKALEIKKQEWKLEQLAadlskYEQELYDLKEEYDRVEKE 484

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  576 MKEAQEEIAFLKSQLQGKRPEgdyeVLDRREVQLMESEGPPSV--------------------TAGDVLCAPSDESSGPA 635
Cdd:TIGR02169  485 LSKLQRELAEAEAQARASEER----VRGGRAVEEVLKASIQGVhgtvaqlgsvgeryataievAAGNRLNNVVVEDDAVA 560

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  636 AEEEQagMKDRHRASEAG--PLN---DAGMELSSPKLDGVDKSL------------AVSHVCQ--------------CHQ 684
Cdd:TIGR02169  561 KEAIE--LLKRRKAGRATflPLNkmrDERRDLSILSEDGVIGFAvdlvefdpkyepAFKYVFGdtlvvedieaarrlMGK 638

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  685 GELERLKTQVLELETSLHTAEETYKRNLSEKVKEISSLTQLSEEvKESAEEARSTLAAVTEERDQLLYqvkeldvlaELR 764
Cdd:TIGR02169  639 YRMVTLEGELFEKSGAMTGGSRAPRGGILFSRSEPAELQRLRER-LEGLKRELSSLQSELRRIENRLD---------ELS 708

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  765 ARVQELESSLAEAEKQRgldyESQRAQHNLLTEQIHSLSIEAKSKDVKIEALQRELDGVQLQFCEQGTQMKTLQSQLEAK 844
Cdd:TIGR02169  709 QELSDASRKIGEIEKEI----EQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDL 784

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  845 ERevREGTERLRDISQEMEGLSQALSQKELEIAKMDQLLLEKQKDVETLQQTIQEKDQQVTELSF---SMTEKMVQLNEE 921
Cdd:TIGR02169  785 EA--RLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEqikSIEKEIENLNGK 862

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  922 KFSLGVEIKTLKEQLNLLSRTEEATKEQVEESGAgsslKLGHDESGQEGLQQELELLRKESEQRKRKLQAalinrkeLLQ 1001
Cdd:TIGR02169  863 KEELEEELEELEAALRDLESRLGDLKKERDELEA----QLRELERKIEELEAQIEKKRKRLSELKAKLEA-------LEE 931

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1002 KVSQLEEELAKVREDSRKEIPFG--ENERRKLEEDRENRDDPEEWGTSKWREVEASLKQtISEKEVELEGIRRDLKEKTA 1079
Cdd:TIGR02169  932 ELSEIEDPKGEDEEIPEEELSLEdvQAELQRVEEEIRALEPVNMLAIQEYEEVLKRLDE-LKEKRAKLEEERKAILERIE 1010


                   ....*
gi 1039751015 1080 AEEEL 1084
Cdd:TIGR02169 1011 EYEKK 1015
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1357-2150 6.66e-11

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 68.56  E-value: 6.66e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1357 ELLKQELESSQLKVAGLE-HLKTLQPELDALHKHMGQKEEEVNYLYGQLSEK-EQTLTTVQTEMVE---QERLIKALHTQ 1431
Cdd:TIGR02169  233 EALERQKEAIERQLASLEeELEKLTEEISELEKRLEEIEQLLEELNKKIKDLgEEEQLRVKEKIGEleaEIASLERSIAE 312

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1432 LEMQAKEHEERLKQAQVEICELKKKPTELEEETNAKQQLQRKLQAALISRKEalKENKSLQEqlssardaverltksLAD 1511
Cdd:TIGR02169  313 KERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKE--ELEDLRAE---------------LEE 375

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1512 VESQVSVQNQEKDAVLGKLTILQEERDKLIAEMDRFLLENQSLSGSCESLKLALGGLTEDKEKLMEELESVRsskmAEST 1591
Cdd:TIGR02169  376 VDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKA----LEIK 451

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1592 EWQEKHKELQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQELYAKLRSTESDKREREKQLQDAEQEMEEMKEKMRKFA 1671
Cdd:TIGR02169  452 KQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLG 531

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1672 KSKQQKILELE-EENDRLRAEAQPVGGTGESMEALLSSNSSLKEE---LEKITLEHKTLSKefealMAEKDALS------ 1741
Cdd:TIGR02169  532 SVGERYATAIEvAAGNRLNNVVVEDDAVAKEAIELLKRRKAGRATflpLNKMRDERRDLSI-----LSEDGVIGfavdlv 606

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1742 ---EETRNLKLQVEAQVLKQASLEATEKSDE-------PKDVIEEVTQAVVGKSQERDALSDSAKLEDSEailmgdgakP 1811
Cdd:TIGR02169  607 efdPKYEPAFKYVFGDTLVVEDIEAARRLMGkyrmvtlEGELFEKSGAMTGGSRAPRGGILFSRSEPAEL---------Q 677

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1812 GVSETFSSHDDIKNYLQQ-LDQLKGRIAELEMEKQKDRELSQALENEKNALLTQISAKDSELKLLEEEVtkrttlnQQIQ 1890
Cdd:TIGR02169  678 RLRERLEGLKRELSSLQSeLRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDL-------SSLE 750

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1891 EELCRVTKLKETAEEEKDDLEERLMNQLAELNgsignyyqdvtdaQIKNEQLESEMRNLQRCVSELEEEKQQLVKEKTKV 1970
Cdd:TIGR02169  751 QEIENVKSELKELEARIEELEEDLHKLEEALN-------------DLEARLSHSRIPEIQAELSKLEEEVSRIEARLREI 817

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1971 ESEIRKEYMEKIQGAQKGPANKSHAKELQELLREKQQEVKQLQKDCIRYLERISALEKTVKALEFVHTESQKDLDVTKGN 2050
Cdd:TIGR02169  818 EQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQ 897

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2051 LAQAVEHRKKAQAELSSFKILLDDTQsEAARVLADNLK----LKKELQSNKESIKS--QIKQKDEDLLRRLEQAE----- 2119
Cdd:TIGR02169  898 LRELERKIEELEAQIEKKRKRLSELK-AKLEALEEELSeiedPKGEDEEIPEEELSleDVQAELQRVEEEIRALEpvnml 976

                          810       820       830
                   ....*....|....*....|....*....|....*.
gi 1039751015 2120 -----EKHRKEKKNMQEKLDALHREKAHVEETLAEI 2150
Cdd:TIGR02169  977 aiqeyEEVLKRLDELKEKRAKLEEERKAILERIEEY 1012
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2208-2752 1.51e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 67.27  E-value: 1.51e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2208 QTKEEEVRLKEENCIALKDQLRQMAIhmEELKITVSRLEHDKEiwesKAQTELQHHQKAYDKLQEENKELTSQLEDARQL 2287
Cdd:COG1196    216 RELKEELKELEAELLLLKLRELEAEL--EELEAELEELEAELE----ELEAELAELEAELEELRLELEELELELEEAQAE 289

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2288 YHDSKNELTKLESELKSLKDQTTDLNNSLEKCKEHENNLEGIIKQQEADIQNCKFSCEQLETDLAASRELTSRLHDEINA 2367
Cdd:COG1196    290 EYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLE 369

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2368 KEQKIISLLSGKEEAIQLAVEELHQQ--HSKEIKELENLLSQEEEENVALEEENKRALEKTNQLTEALEAIKKESFEQKA 2445
Cdd:COG1196    370 AEAELAEAEEELEELAEELLEALRAAaeLAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAE 449

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2446 QLDSFVKSMSSLQDDRDRIVSDYRQLEERHLSAILEKDQLIQDAAAENN---------------KLKEEMRGLRSHMDDL 2510
Cdd:COG1196    450 EEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEaeadyegflegvkaaLLLAGLRGLAGAVAVL 529

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2511 NSENAKLDAELVQYRRDLNEVIAIKDSQQKQLLDAQLQQNKELRNECTKLEERLKGLEAEKQSLQMSSDALQKEKQGLSK 2590
Cdd:COG1196    530 IGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLR 609

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2591 EIKNLQTQLTALQEEGTL--------GVYHAQLKAKEEELQRLNMALSSSQKRTADLEEELVCVQKEATRKVSEIEDQLK 2662
Cdd:COG1196    610 EADARYYVLGDTLLGRTLvaarleaaLRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLA 689

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2663 KELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLTVTKENKDLMAQIQAFGRSMSSLQDSRDHATEELGDLKKKY 2742
Cdd:COG1196    690 EEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELEREL 769

                          570
                   ....*....|
gi 1039751015 2743 DASLKELAQL 2752
Cdd:COG1196    770 ERLEREIEAL 779
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 734-1583 1.66e-10

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 67.40  E-value: 1.66e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  734 EEARSTLAAVTEERDQLLYQVKELD-VLAELRARVQELESSLAEAEKQRGLDYESQRAQHNLLTEQIHSLSIEAKSKDVK 812
Cdd:TIGR02169  166 AEFDRKKEKALEELEEVEENIERLDlIIDEKRQQLERLRREREKAERYQALLKEKREYEGYELLKEKEALERQKEAIERQ 245

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  813 IEALQRELDGVQLQFCEQGTQMKTLQSQLEAKEREVRE-GTERLRDISQEMEGLSQALSQKELEIAKMDQLLLEKQKDVE 891
Cdd:TIGR02169  246 LASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDlGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLA 325

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  892 TLQQTIQEKDQQVTELSfsmtEKMVQLNEEKFSLGVEIKTLKEQLNLLsrteEATKEQVEESGAGSSLKLGHDESGQEGL 971
Cdd:TIGR02169  326 KLEAEIDKLLAEIEELE----REIEEERKRRDKLTEEYAELKEELEDL----RAELEEVDKEFAETRDELKDYREKLEKL 397

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  972 QQELELLRKESEQRKRKLQAALINRKELLQKVSQLEE---ELAKVREDSRKEIPFGENERRKLEEDRENRDDPEEWGTSK 1048
Cdd:TIGR02169  398 KREINELKRELDRLQEELQRLSEELADLNAAIAGIEAkinELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEE 477

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1049 WREVE---ASLKQTISEKEVELEGIRRDLKEKTAAEEELQAVVQRM---TRDLQSKTKQIDL---------LQEEVTENQ 1113
Cdd:TIGR02169  478 YDRVEkelSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVhgtVAQLGSVGERYATaievaagnrLNNVVVEDD 557

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1114 ATIQKLVTgTMDAGNGGSAA--PVKETAASSPPGAggeehwKPELEGrILDLEKDKTQLQKKLQEAL--IARKAILKKAQ 1189
Cdd:TIGR02169  558 AVAKEAIE-LLKRRKAGRATflPLNKMRDERRDLS------ILSEDG-VIGFAVDLVEFDPKYEPAFkyVFGDTLVVEDI 629

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1190 EKEKQLKEELReqkdaYHHLQGQFHEQNKEKENIADQLRQLQCQAResidrqlpgtgQQEPGPPAPSLEGISLEDTEPAS 1269
Cdd:TIGR02169  630 EAARRLMGKYR-----MVTLEGELFEKSGAMTGGSRAPRGGILFSR-----------SEPAELQRLRERLEGLKRELSSL 693

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1270 ESDLHAAQPSPPGETAALQ-ATVSVAQIQAQLKEMEVEKEELELKVSSIASELAKKSEEVLLLQDQINEQGLEIQNLKAA 1348
Cdd:TIGR02169  694 QSELRRIENRLDELSQELSdASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEED 773

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1349 SVEAQAHTELLKQELESSQLK--VAGLEHLKTLQPELDALHKHMGQKEEEVNYLYGQLSEKEQTLTTVQTEMVEQERLIK 1426
Cdd:TIGR02169  774 LHKLEEALNDLEARLSHSRIPeiQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIE 853

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1427 ALHTQLEMQAKEHEERLKQAQVEICELKKKPTELEEE----TNAKQQLQRKLQAALISRKEALKENKSLQEQLSSARDAV 1502
Cdd:TIGR02169  854 KEIENLNGKKEELEEELEELEAALRDLESRLGDLKKErdelEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEEL 933

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1503 ERLTKSLADVESQVsvqnqEKDAVLGKltiLQEERDKLIAEMDRFLLENQSLSGSCESLKLALGGLTEDKEKLMEELESV 1582
Cdd:TIGR02169  934 SEIEDPKGEDEEIP-----EEELSLED---VQAELQRVEEEIRALEPVNMLAIQEYEEVLKRLDELKEKRAKLEEERKAI 1005


                   .
gi 1039751015 1583 R 1583
Cdd:TIGR02169 1006 L 1006
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2419-3160 4.93e-10

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 65.85  E-value: 4.93e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2419 NKRALEKTNQLTEALEAIKKEsfEQKAQLDSFVKSMSSLQDDRDR---IVSDYRQLEERHLSAILEKDQLIQDAAAENNK 2495
Cdd:TIGR02168  201 QLKSLERQAEKAERYKELKAE--LRELELALLVLRLEELREELEElqeELKEAEEELEELTAELQELEEKLEELRLEVSE 278

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2496 LKEEMRGLRSHMDDLNSENAKLDAELVQYRRDLNEViaikdSQQKQLLDAQLQQNKELRNEctkLEERLKGLEAEKQSLQ 2575
Cdd:TIGR02168  279 LEEEIEELQKELYALANEISRLEQQKQILRERLANL-----ERQLEELEAQLEELESKLDE---LAEELAELEEKLEELK 350

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2576 MSSDALQKEKQGLSKEIKNLQTQLTALQEEgtlgvyHAQLKAKEEELQRlnmALSSSQKRTADLEEELVCVQKEATRKVS 2655
Cdd:TIGR02168  351 EELESLEAELEELEAELEELESRLEELEEQ------LETLRSKVAQLEL---QIASLNNEIERLEARLERLEDRRERLQQ 421

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2656 EIEDQLKKELKHLHHDAGIMRNETETAEErvaELARDLVEMEQKLLTVTKENKDLMAQIQAFGRSMSSLQdSRDHATEEL 2735
Cdd:TIGR02168  422 EIEELLKKLEEAELKELQAELEELEEELE---ELQEELERLEEALEELREELEEAEQALDAAERELAQLQ-ARLDSLERL 497

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2736 GDLKKKYDASLKELAQLKEWqdssregdvLSQAAFPLSTSENVLSRLEKLNQQLTSKDEQLLhLSSELESSHNQVQSISK 2815
Cdd:TIGR02168  498 QENLEGFSEGVKALLKNQSG---------LSGILGVLSELISVDEGYEAAIEAALGGRLQAV-VVENLNAAKKAIAFLKQ 567

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2816 AmtslqNERDRLWSELEKFRKSE-EGKQRAAAPSAASSPAEVQSLKKAMSSLQNDRDRLL------KELKNLQQQYLQMS 2888
Cdd:TIGR02168  568 N-----ELGRVTFLPLDSIKGTEiQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLggvlvvDDLDNALELAKKLR 642

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2889 QEMT-------------------------------ELRPLKAQLQESQDQTKALQVMEEELRQENLSWQHELRQLRMEKN 2937
Cdd:TIGR02168  643 PGYRivtldgdlvrpggvitggsaktnssilerrrEIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELE 722

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2938 SWELHERRMKEQfLMAISDKDQQLGHLQSLLRELRSSSQAQILSTQYQR-QASPETSASLDGSQKLVYETELLRTQLNDS 3016
Cdd:TIGR02168  723 ELSRQISALRKD-LARLEAEVEQLEERIAQLSKELTELEAEIEELEERLeEAEEELAEAEAEIEELEAQIEQLKEELKAL 801

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 3017 LKEIHQKELRIQQLNSKFSQLLEEKNVLSTQLSDASQSLRENQHHYSNLFNHCAILEKEVQKLQAGP--LNTDVapgapq 3094
Cdd:TIGR02168  802 REALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIeeLESEL------ 875

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1039751015 3095 EKNGMHRKSEPETTGEEQPSFSEVQQQLCNTKQDLRELKKLLEEERDQRLTAENALSLAKEQIRRL 3160
Cdd:TIGR02168  876 EALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNL 941
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2397-2935 6.16e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 65.34  E-value: 6.16e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2397 EIKELENLLSQEEEENVALEEENKRALEKTNQLTEALEAIKKESFEQKAQLDSFVKSMSSLQDDRDRIVSDYRQLEERHL 2476
Cdd:COG1196    233 KLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRR 312

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2477 SAILEKDQL---IQDAAAENNKLKEEMRGLRSHMDDLNSENAKLDAELVQYRRDLNEVIAIKDSQQKQLLDAQLQQNKEL 2553
Cdd:COG1196    313 ELEERLEELeeeLAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEAL 392

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2554 RNEcTKLEERLKGLEAEKQSLQMSSDALQKEKQGLSKEIKNLQTQLTALQEEgtLGVYHAQLKAKEEELQRLNMALSSSQ 2633
Cdd:COG1196    393 RAA-AELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEA--LEEAAEEEAELEEEEEALLELLAELL 469

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2634 KRTADLEEELVCVQKEATRKVSEIEDQLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLTVTKENKDLMAQ 2713
Cdd:COG1196    470 EEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQ 549

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2714 IQAFGRSMSSLQDSRDHATEELGDLKKKYDASLKELAQLKEWQDSSREGDVLSQAAFPLSTSENVLSRLEKLNQQLTSKD 2793
Cdd:COG1196    550 NIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVA 629

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2794 EQLLHLSSELESSHNQVQSISKAMTSLQNERDRLwselekfRKSEEGKQRAAAPSAASSPAEVQSLKKAMSSLQNDRDRL 2873
Cdd:COG1196    630 ARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLT-------GGSRRELLAALLEAEAELEELAERLAEEELELEEALLAE 702

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1039751015 2874 LKELKNLQQQYLQMSQEMTELRPLKAQLQESQDQTKALQVMEEELRQENL-----------SWQHELRQLRME 2935
Cdd:COG1196    703 EEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEAleelpeppdleELERELERLERE 775
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 153-798 6.64e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 65.34  E-value: 6.64e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  153 HELQEKEKLISSLQAQLDQSEQASQLDKSSAEMEDFVLMKQQLQEKEELISTLQTQLSQTQAEQAAQLSSMQQVVREKDA 232
Cdd:COG1196    216 RELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLA 295

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  233 RFET-------QVRLHEDELLQLVTQSDVETEMQQKLRVMQRKLEEHEEALLGRAQVVDLLQKELTSAEQRNQVLSQQLQ 305
Cdd:COG1196    296 ELARleqdiarLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELA 375

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  306 LLEAEHNTLKNTMETERQESKtlmekvelevaerklsfhNLQEEMHQLQGQLERAGQAQADLETQYSALQQRHKTEMEEK 385
Cdd:COG1196    376 EAEEELEELAEELLEALRAAA------------------ELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEE 437

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  386 taciLSLQKNEQELQSACAALKEENSKLLQEKHDQAAESAQAMRQLEDQLQQKSKEISQFVNKPNLQKNETASQTSLPDV 465
Cdd:COG1196    438 ----EEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAA 513

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  466 NNEGDQAVMEETVASLQKRVVELENEKGALLLssGELEELKAENEKLSSRITLLEAQNRAGEAdgTVCEVSTAGTTLLNR 545
Cdd:COG1196    514 LLLAGLRGLAGAVAVLIGVEAAYEAALEAALA--AALQNIVVEDDEVAAAAIEYLKAAKAGRA--TFLPLDKIRARAALA 589

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  546 SDSSPEENGQAVLENTFsqkhkelsvllvemkEAQEEIAFLksqlqgkRPEGDYEVLDRREVQLMESEGPPSVTAGDVLc 625
Cdd:COG1196    590 AALARGAIGAAVDLVAS---------------DLREADARY-------YVLGDTLLGRTLVAARLEAALRRAVTLAGRL- 646

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  626 apsDESSGPAAEEEQAGMKDRHRASEAGPLNDAGMELSSPKLDGVDKslavshvcqcHQGELERLKTQVLELETSLHTAE 705
Cdd:COG1196    647 ---REVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAE----------EELELEEALLAEEEEERELAEAE 713

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  706 ETYKRNLSEKVKEISSLTQLSEEVKESAEEARSTLAAVTEERDQLLYQVKELDV-LAELRARVQELES--SLAEAEkqrg 782
Cdd:COG1196    714 EERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELEReLERLEREIEALGPvnLLAIEE---- 789

                          650
                   ....*....|....*.
gi 1039751015  783 ldYESQRAQHNLLTEQ 798
Cdd:COG1196    790 --YEELEERYDFLSEQ 803
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 683-1236 8.52e-10

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 65.08  E-value: 8.52e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  683 HQGELERLKTQVLELETSLHTAE---ETYKRNLSEKVKEISSLTQLSEEVKESAEEARSTLA----AVTEERDQLLYQVK 755
Cdd:TIGR02168  307 LRERLANLERQLEELEAQLEELEsklDELAEELAELEEKLEELKEELESLEAELEELEAELEelesRLEELEEQLETLRS 386

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  756 ELDVL----AELRARVQELESSLAEAEKQRG-LDYESQRAQHNLLTEQIHSLSIEAKSKDVKIEALQRELDGVQLQFCEQ 830
Cdd:TIGR02168  387 KVAQLelqiASLNNEIERLEARLERLEDRRErLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEEL 466

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  831 GTQMKTLQSQLEAKEREVREGTER---LRDISQEMEGLSQALSQ----------------------KELEIAK------- 878
Cdd:TIGR02168  467 REELEEAEQALDAAERELAQLQARldsLERLQENLEGFSEGVKAllknqsglsgilgvlselisvdEGYEAAIeaalggr 546

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  879 MDQLLLEKQ----KDVETLQQ------------TIQEKDQQVTELSFSMTEKMVQL-------NEEKFSLGVE------- 928
Cdd:TIGR02168  547 LQAVVVENLnaakKAIAFLKQnelgrvtflpldSIKGTEIQGNDREILKNIEGFLGvakdlvkFDPKLRKALSyllggvl 626

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  929 -IKTLKEQLNLLSRTEEATK---EQVEESGAGSSLKLGHDE--SGQEGLQQELELLRKESEQRKRKLQAALINRKELLQK 1002
Cdd:TIGR02168  627 vVDDLDNALELAKKLRPGYRivtLDGDLVRPGGVITGGSAKtnSSILERRREIEELEEKIEELEEKIAELEKALAELRKE 706

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1003 VSQLEEELAKVREDSRKEIPFGENERRKLEEDRENRDDPEEWGTSKWREVEaSLKQTISEKEVELEGIRRDLKEKTAAEE 1082
Cdd:TIGR02168  707 LEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELT-ELEAEIEELEERLEEAEEELAEAEAEIE 785

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1083 ELQAVVQRMTRDLQSKTKQIDLLQEEVTENQATIQKLVTGTMDAGNggSAAPVKETAASSPPGAGGEEHWKPELEGRILD 1162
Cdd:TIGR02168  786 ELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLER--RIAATERRLEDLEEQIEELSEDIESLAAEIEE 863

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1163 LEKDKTQLQKKLQEALIARKAI----------LKKAQEKEKQLKEELREQKDAYHHLQGQFHEQNKEKENIADQLRQLQC 1232
Cdd:TIGR02168  864 LEELIEELESELEALLNERASLeealallrseLEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQE 943


                   ....
gi 1039751015 1233 QARE 1236
Cdd:TIGR02168  944 RLSE 947
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 727-1476 9.56e-10

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 64.70  E-value: 9.56e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  727 EEVKESAEEARSTLAAVTEERDQLLYQVKELDVLAELRARVQELESSL-------AEAEKQRGL-DYESQRAQHNLLTEQ 798
Cdd:TIGR02169  180 EEVEENIERLDLIIDEKRQQLERLRREREKAERYQALLKEKREYEGYEllkekeaLERQKEAIErQLASLEEELEKLTEE 259

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  799 IHSLSIEAKSKDVKIEALQREL----DGVQLQFCEQGTQMKTLQSQLEAK-----------EREVREGTERLRDISQEME 863
Cdd:TIGR02169  260 ISELEKRLEEIEQLLEELNKKIkdlgEEEQLRVKEKIGELEAEIASLERSiaekereledaEERLAKLEAEIDKLLAEIE 339

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  864 GLSQALSQKELEIAKMDQLLLEKQKDVETLQQTIQEKDQQVTELSfsmtEKMVQLNEEKFSLGVEIKTLKEQLNLLsrte 943
Cdd:TIGR02169  340 ELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETR----DELKDYREKLEKLKREINELKRELDRL---- 411

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  944 EATKEQVEESGAGSSLKLGHDESGQEGLQQELELLRKESEQRKRKLQAALINRKELLQKVSQLEEELAKV---REDSRKE 1020
Cdd:TIGR02169  412 QEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVekeLSKLQRE 491

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1021 IPFGENERRKLEEDRENRDDPEEWGTSKWREVEASLKQTISEKEvelegiRRDLKEKTAAEEELQAVV------------ 1088
Cdd:TIGR02169  492 LAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGE------RYATAIEVAAGNRLNNVVveddavakeaie 565

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1089 -------QRMT----RDLQSKTKQIDLLQEE----------------------------VTENQATIQKL---------- 1119
Cdd:TIGR02169  566 llkrrkaGRATflplNKMRDERRDLSILSEDgvigfavdlvefdpkyepafkyvfgdtlVVEDIEAARRLmgkyrmvtle 645

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1120 ---------VTGTMDAGNGGSAAPVKETAASsppgaggeehwkPELEGRILDLEKDKTQLQKKLQEALIARKAILKKAQE 1190
Cdd:TIGR02169  646 gelfeksgaMTGGSRAPRGGILFSRSEPAEL------------QRLRERLEGLKRELSSLQSELRRIENRLDELSQELSD 713

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1191 KEKQLKEELREQKDAyhhlqGQFHEQNKEK-ENIADQLRQLQcQARESIDRQLPgtgqqepgppapslegiSLEDTEPAS 1269
Cdd:TIGR02169  714 ASRKIGEIEKEIEQL-----EQEEEKLKERlEELEEDLSSLE-QEIENVKSELK-----------------ELEARIEEL 770

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1270 ESDLHAAQPsppgETAALQATVS---VAQIQAQLKEMEVEKEELELKVSSIASELAKKSEEVLLLQDqineqglEIQNLK 1346
Cdd:TIGR02169  771 EEDLHKLEE----ALNDLEARLShsrIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEK-------EIQELQ 839

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1347 AASVEAQAHTELLKQELESSQLKVAGLE-HLKTLQPELDALHKHMGQKEEEVNYLYGQLSEKEQTLTTVQTEMVEQERLI 1425
Cdd:TIGR02169  840 EQRIDLKEQIKSIEKEIENLNGKKEELEeELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRL 919

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1039751015 1426 KALHTQLEMQakehEERLKQAQVEICELKKKPTELEEETNAKQQLQRKLQA 1476
Cdd:TIGR02169  920 SELKAKLEAL----EEELSEIEDPKGEDEEIPEEELSLEDVQAELQRVEEE 966
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1167-2029 9.92e-10

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 64.69  E-value: 9.92e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1167 KTQLQKKLQEALIARKAILKKAQEKEKQL---KEELREQKDAYHHLQGQFHEQNKEKENIADQLRQLQCQaresidrqlp 1243
Cdd:TIGR02168  199 ERQLKSLERQAEKAERYKELKAELRELELallVLRLEELREELEELQEELKEAEEELEELTAELQELEEK---------- 268

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1244 gtgqqepgppapsLEGISLEDTEpaSESDLHAAQpsppgetAALQATVSvaqiqaqlkemevekeelelKVSSIASELAK 1323
Cdd:TIGR02168  269 -------------LEELRLEVSE--LEEEIEELQ-------KELYALAN--------------------EISRLEQQKQI 306

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1324 KSEEVLLLQDQINEQGLEIQNLKAASVEAQAHTELLKQELESSQLKVAGL-EHLKTLQPELDALHKHMGQKEEEVNYLYG 1402
Cdd:TIGR02168  307 LRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLeAELEELEAELEELESRLEELEEQLETLRS 386

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1403 QLSEKEQTLTTVQTEMVEQERLIKALHTQLEMQAKEHEERLKQAQveicelKKKPTELEEETNAKQQLQRKLQAALISRK 1482
Cdd:TIGR02168  387 KVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLE------EAELKELQAELEELEEELEELQEELERLE 460

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1483 EALKENKSLQEQLSSARDAVERLTKSL-ADVESQVSVQNQEKDAVLGKLTILQeERDKLIAEMDRFLLENQSLSGSCESL 1561
Cdd:TIGR02168  461 EALEELREELEEAEQALDAAERELAQLqARLDSLERLQENLEGFSEGVKALLK-NQSGLSGILGVLSELISVDEGYEAAI 539

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1562 KLALGG-----LTEDKEKLMEELESVRSSKMAEST---EWQEKHKELQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQ 1633
Cdd:TIGR02168  540 EAALGGrlqavVVENLNAAKKAIAFLKQNELGRVTflpLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALS 619

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1634 ELYAKLRSTESdkrerekqLQDAEQEmeemkekmrkfAKSKQQKILELEEENDRLRAEAQPVGGTGESMEALLssnsSLK 1713
Cdd:TIGR02168  620 YLLGGVLVVDD--------LDNALEL-----------AKKLRPGYRIVTLDGDLVRPGGVITGGSAKTNSSIL----ERR 676

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1714 EELEKITLEHKTLSKEFEALMAEKDALSEETRNLKLQVEAqvLKQASLEATEKSDEPKDVIEEVTQavvgKSQERDALSD 1793
Cdd:TIGR02168  677 REIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQ--LRKELEELSRQISALRKDLARLEA----EVEQLEERIA 750

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1794 SAKLEDSEAIlmgdgakpgvsetfsshDDIKNYLQQLDQLKGRIAELEMEKQKDRELSQALENEKNALLTQISAKDSELK 1873
Cdd:TIGR02168  751 QLSKELTELE-----------------AEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELT 813

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1874 LLEEEVTKRTTLNQQIQEELCRVTKLKETAEEEKDDLEErlmnQLAELNGSIGNYYQDVTDAQIKNEQLESEMRNLQRCV 1953
Cdd:TIGR02168  814 LLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSE----DIESLAAEIEELEELIEELESELEALLNERASLEEAL 889

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1039751015 1954 SELEEEKQQLVKEKTKVESEIRKEYMEkiqgaqkgpankshAKELQELLREKQQEVKQLQKDCIRYLERISALEKT 2029
Cdd:TIGR02168  890 ALLRSELEELSEELRELESKRSELRRE--------------LEELREKLAQLELRLEGLEVRIDNLQERLSEEYSL 951
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1996-2605 1.43e-09

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 63.89  E-value: 1.43e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1996 KELQELLREKQQEVKQLQKDCIRYLERISALEKTVKALEFVHTESQKDLDVTKGNLAQAVEHRKKAQAELSSFKILLDDT 2075
Cdd:TIGR04523   43 KTIKNELKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDLSKINSEIKNDKEQKNKL 122

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2076 QSEAArvladnlKLKKELQSNKESIKSQIKQ--KDEDLLRRLEQAEEKHRKEKKNMQEKLDALHREKAHVEETLAEIQVS 2153
Cdd:TIGR04523  123 EVELN-------KLEKQKKENKKNIDKFLTEikKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNK 195

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2154 LTR----------KDQEMKELQGSLDSTLAQLAAFTKSMSSLQDDRDRVIDEAKKWERRFGDAIQTKEEEvrlkeencia 2223
Cdd:TIGR04523  196 LLKlelllsnlkkKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKI---------- 265

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2224 lKDQLRQMAIHMEELKITVSRLEhdKEIWESKAQTELQHHQKAydklQEENKELTSQLEdarqlyhDSKNELTKLESELK 2303
Cdd:TIGR04523  266 -KKQLSEKQKELEQNNKKIKELE--KQLNQLKSEISDLNNQKE----QDWNKELKSELK-------NQEKKLEEIQNQIS 331

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2304 SLKDQTTDLNNSLEKCKEHENNLEGIIKQQEADIQNCKFSCEQLETDLAASRELTSRLHDEINAKEQKiISLLSGKEEAI 2383
Cdd:TIGR04523  332 QNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESK-IQNQEKLNQQK 410

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2384 QLAVEELHQQHSKEIKELENLLSQEEEENVALeeenKRALEKTNQLTEALEAIKKESFEQKAQLDSFVKSMSSLQDDRDR 2463
Cdd:TIGR04523  411 DEQIKKLQQEKELLEKEIERLKETIIKNNSEI----KDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQ 486

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2464 IVSDYRQLEERHLSAILEKDQLIQdaaaENNKLKEEMRGLRSHMDDLNSENAKLDAELVQYRRDLNEviaIKDSQQKQLL 2543
Cdd:TIGR04523  487 KQKELKSKEKELKKLNEEKKELEE----KVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNK---DDFELKKENL 559

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1039751015 2544 DAQLQQNKElrnECTKLEERLKGLEAEKQSLQMSSDALQKEKQGLSKEIKNLQTQLTALQEE 2605
Cdd:TIGR04523  560 EKEIDEKNK---EIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKE 618
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1911-2481 1.71e-09

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 63.93  E-value: 1.71e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1911 EERLMNQLAELNGSIGNYYQDVTDAQIKNEQLESEMRNLQRCVSELEEEKQ---QLVKEKTKVESEIRKEyMEKIQGAQK 1987
Cdd:PRK03918   188 TENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEeieELEKELESLEGSKRKL-EEKIRELEE 266

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1988 GPANKshaKELQELLREKQQEVKQLQKDCIRYLERISALEKTVKALefvhtesqKDLDVTKGNLAQAVEHRKKAQAELSS 2067
Cdd:PRK03918   267 RIEEL---KKEIEELEEKVKELKELKEKAEEYIKLSEFYEEYLDEL--------REIEKRLSRLEEEINGIEERIKELEE 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2068 FKILLDDTQseaarvladnlKLKKELQSNKESIKSQIKQKDEdlLRRLEQAEEKHRKEKKN-----MQEKLDALHREKAH 2142
Cdd:PRK03918   336 KEERLEELK-----------KKLKELEKRLEELEERHELYEE--AKAKKEELERLKKRLTGltpekLEKELEELEKAKEE 402

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2143 VEETLAEIQVSLTRKDQEMKELQGSL-------------------DSTLAQLAAFTKSMSSLQDDRDRVIDEAKKWERRF 2203
Cdd:PRK03918   403 IEEEISKITARIGELKKEIKELKKAIeelkkakgkcpvcgrelteEHRKELLEEYTAELKRIEKELKEIEEKERKLRKEL 482

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2204 gdaiqTKEEEVRLKEENCIALKDQLRQMAIHMEELKitvsrlEHDKEIWESKAqTELQHHQKAYDKLQEENKELTSQLED 2283
Cdd:PRK03918   483 -----RELEKVLKKESELIKLKELAEQLKELEEKLK------KYNLEELEKKA-EEYEKLKEKLIKLKGEIKSLKKELEK 550

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2284 ARQLyhdsKNELTKLESELKSLKDQTTDLNNSLEKCK-EHENNLEGIIKQQEA------DIQNCKFSCEQLETDLAASRE 2356
Cdd:PRK03918   551 LEEL----KKKLAELEKKLDELEEELAELLKELEELGfESVEELEERLKELEPfyneylELKDAEKELEREEKELKKLEE 626

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2357 LTSRLHDEINAKEQKIISLLSGKEEAIQLAVEELHQQHSKEIKELENLLSQEEEENVALEEENKRALEKTNQLTEALEAI 2436
Cdd:PRK03918   627 ELDKAFEELAETEKRLEELRKELEELEKKYSEEEYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEER 706

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*
gi 1039751015 2437 KKesfeQKAQLDSFVKSMSSLQDDRDRIVSDYRQLEERHLSAILE 2481
Cdd:PRK03918   707 EK----AKKELEKLEKALERVEELREKVKKYKALLKERALSKVGE 747
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 330-1119 2.73e-09

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 63.54  E-value: 2.73e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  330 EKVELEVAERKLSFHNLQEEMHQLQGQLERAGQAQADLETQYSALQqrhkTEMEEKTACILSLQKNEQELQSACAALKEE 409
Cdd:TIGR02168  221 ELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELE----EKLEELRLEVSELEEEIEELQKELYALANE 296

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  410 NSKLLQEKhdqaAESAQAMRQLEDQLQQKSKEISQFVNKPNLQKNETASqtslpdvnnegdqavMEETVASLQKRVVELE 489
Cdd:TIGR02168  297 ISRLEQQK----QILRERLANLERQLEELEAQLEELESKLDELAEELAE---------------LEEKLEELKEELESLE 357

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  490 NEkgalllssgeLEELKAENEKLSSRITLLEAQNRAgeadgtvcevstagttllNRSDSSPEENGQAVLENTFSQKHKEL 569
Cdd:TIGR02168  358 AE----------LEELEAELEELESRLEELEEQLET------------------LRSKVAQLELQIASLNNEIERLEARL 409

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  570 SVLLVEMKEAQEEIAFLKSQLQGKRPEGDYEVLDRREVQLMESEGppSVTAGDVLCAPSDESSGPAAEEEQAGMKDRHRA 649
Cdd:TIGR02168  410 ERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQE--ELERLEEALEELREELEEAEQALDAAERELAQL 487

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  650 SEAGPLNDAGMELSSPKLDGVDKSLAVSHVCQCHQGELerlkTQVLELETSLHTAEETY---------KRNLSEKVKEIS 720
Cdd:TIGR02168  488 QARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVL----SELISVDEGYEAAIEAAlggrlqavvVENLNAAKKAIA 563

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  721 SLTQ---------------------LSEEVKESAEEARSTLAAVTEERDQL----------LYQVKELDVLAELRARVQE 769
Cdd:TIGR02168  564 FLKQnelgrvtflpldsikgteiqgNDREILKNIEGFLGVAKDLVKFDPKLrkalsyllggVLVVDDLDNALELAKKLRP 643

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  770 LES---------------SLAEAEKQRGLDYESQ-----RAQHNLLTEQIHSLSIEAKSKDVKIEALQRELDGVQLQFCE 829
Cdd:TIGR02168  644 GYRivtldgdlvrpggviTGGSAKTNSSILERRReieelEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEE 723

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  830 QGTQMKTLQSQLEAKEREVREGTERLRDISQEMEGLSQALSQKELEIAKMDQLLLEKQKDVETLQQTIQEKDQQVTELSF 909
Cdd:TIGR02168  724 LSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALRE 803

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  910 SMTEKMVQLNEEKFSLGVEIKTLKEQLNLLSRTE------EATKEQVEESGAGSSLKLGHDESGQEGLQQELELLRKESE 983
Cdd:TIGR02168  804 ALDELRAELTLLNEEAANLRERLESLERRIAATErrledlEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERA 883

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  984 QRKRKLQAALINRKELLQKVSQLEEELAKVREDSRKEIPFGENERRKLEEDRENRDDPEEWGTSKWREVEASLKQTISEK 1063
Cdd:TIGR02168  884 SLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKI 963

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1039751015 1064 EVELEGIRRDLKEKT-----------AAEEELQAVVQRmtrdLQSKTKQIDLLQEEVTENQATIQKL 1119
Cdd:TIGR02168  964 EDDEEEARRRLKRLEnkikelgpvnlAAIEEYEELKER----YDFLTAQKEDLTEAKETLEEAIEEI 1026
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 2091-2668 4.00e-09

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 62.73  E-value: 4.00e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2091 KELQSNKESIKSQIKQKdEDLLRRLEQAEEKHRKEKKNMQEKLdalhrekahveETLAEIQVSLTRKDQEMKELQGSLDS 2170
Cdd:TIGR04523   36 KQLEKKLKTIKNELKNK-EKELKNLDKNLNKDEEKINNSNNKI-----------KILEQQIKDLNDKLKKNKDKINKLNS 103

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2171 TLAQLAAFTKSMSSLQDDRDRVIDEAKKWERRFGDAIQTKEEEVRLKEENCIALKDQLRQMAIHMEELKITVSRLEHDKE 2250
Cdd:TIGR04523  104 DLSKINSEIKNDKEQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKL 183

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2251 IWESK-AQTELQHHQKAY-----DKLQEENKELTSQLEDARQLYHDSKNELTKLESELKSLKDQTTDLNNSLEKCKEHEN 2324
Cdd:TIGR04523  184 NIQKNiDKIKNKLLKLELllsnlKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQN 263

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2325 NLEGIIKQQEADIQNCKFSCEQLETDLaasRELTSRLHDEINAKEQKIISLLSGKEEAIQLAVEELHQQHSKEIKELENL 2404
Cdd:TIGR04523  264 KIKKQLSEKQKELEQNNKKIKELEKQL---NQLKSEISDLNNQKEQDWNKELKSELKNQEKKLEEIQNQISQNNKIISQL 340

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2405 LSQEEEENVALEEENKRALEKTNQLTE---ALEAIKKESFEQKAQLDSFVKSMSSLQDDRDRIVSDYRQLEERHLSAILE 2481
Cdd:TIGR04523  341 NEQISQLKKELTNSESENSEKQRELEEkqnEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQE 420

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2482 KDQL---IQDAAAENNKLKEEMRGLRSHMDDLNSENAKLDA---ELVQYRRDLNEVIAIKDS---QQKQLLDAQLQQNKE 2552
Cdd:TIGR04523  421 KELLekeIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNtreSLETQLKVLSRSINKIKQnleQKQKELKSKEKELKK 500

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2553 LRNECTKLEERLKGLEAEKQSLQMSSDALQKEKQGLSKEIKNLQTQLTALQEEGTLGVYHAQLKAKEEELQRLNMALSSS 2632
Cdd:TIGR04523  501 LNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDFELKKENLEKEIDEKNKEIEELKQTQKSL 580

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|..
gi 1039751015 2633 QKRTADLEEELVCVQKEATRKVSEIE------DQLKKELKHL 2668
Cdd:TIGR04523  581 KKKQEEKQELIDQKEKEKKDLIKEIEekekkiSSLEKELEKA 622
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2275-2880 5.04e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 62.26  E-value: 5.04e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2275 KELTSQLEDARQlYHDSKNELTKLESELKSLKDQttdlnnslekckehenNLEGIIKQQEADIQNCKFSCEQLETDLAAS 2354
Cdd:COG1196    203 EPLERQAEKAER-YRELKEELKELEAELLLLKLR----------------ELEAELEELEAELEELEAELEELEAELAEL 265

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2355 RELTSRLHDEINAKEQKIiSLLSGKEEAIQLAVEELHQQHSKEIKELENLLSQEEEENVALEEENKRALEKTNQLTEALE 2434
Cdd:COG1196    266 EAELEELRLELEELELEL-EEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEE 344

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2435 AIKkesfEQKAQLDSFVKSMSSLQDDRDRIVSDYRQLEERHLSAILEKDQLIQDAAAENNKLKEemrgLRSHMDDLNSEN 2514
Cdd:COG1196    345 ELE----EAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEE----LEEAEEALLERL 416

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2515 AKLDAELVQYRRDLNEVIAIKDSQQKQLLDAQLQQNKELRNECTKLEERLKGLEAEKQSLQMSSDALQKEKQGLSKEikN 2594
Cdd:COG1196    417 ERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARL--L 494

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2595 LQTQLTALQEEGTLGVYHAQLKAKEEEL-QRLNMALSSSQKRTADLEEELVCVQKEATRKVSEIEDQLKKELKHlhHDAG 2673
Cdd:COG1196    495 LLLEAEADYEGFLEGVKAALLLAGLRGLaGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKA--AKAG 572

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2674 IMRNETETAEERVAELARDLVEMEQKLLTVTKENKDLMAQIQAFGRSMSSLQDSRDHATEELGDLKKKYDASLKELAQLK 2753
Cdd:COG1196    573 RATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLE 652

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2754 EWQDSSREGDVLSQAAFPLSTSENVLSRLEKLNQQLTSKDEQLLHLSSELESSHNQVQSISKAMTSLQNERDRLWSELEK 2833
Cdd:COG1196    653 GEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEA 732

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*..
gi 1039751015 2834 FRKSEEGKQRAAAPSAASSPAEVQSLKKAMSSLQNDRDRLLKELKNL 2880
Cdd:COG1196    733 EREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEAL 779
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 734-1220 6.53e-09

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 62.16  E-value: 6.53e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  734 EEARSTLAAVTEERDQLLYQVKELDVLAELRARVQELESSLAEAEKQRGLDYESQ-RAQHNLLTEQIHSLSIEAKSKDVK 812
Cdd:pfam12128  237 MKIRPEFTKLQQEFNTLESAELRLSHLHFGYKSDETLIASRQEERQETSAELNQLlRTLDDQWKEKRDELNGELSAADAA 316

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  813 IEALQRELDGVQ---LQFCEQG--------TQMKTLQSQLEAKEREVREGTERLRDISQEMEGLSQALSQK-ELEIAKMD 880
Cdd:pfam12128  317 VAKDRSELEALEdqhGAFLDADietaaadqEQLPSWQSELENLEERLKALTGKHQDVTAKYNRRRSKIKEQnNRDIAGIK 396

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  881 QLLlEKQKDVETLQQTIQEKD--QQVTELSFSMTEKMVQLNEEKFSLGVEIKTLKEQLNLLSRTEE--ATKEQVEESGAG 956
Cdd:pfam12128  397 DKL-AKIREARDRQLAVAEDDlqALESELREQLEAGKLEFNEEEYRLKSRLGELKLRLNQATATPEllLQLENFDERIER 475

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  957 SSLKLGHDESGQEGLQQELELLRKESEQRKRKLQAALINRKELLQKVSQLEEEL----AKVREDSRKEIP-FGENERRKL 1031
Cdd:pfam12128  476 AREEQEAANAEVERLQSELRQARKRRDQASEALRQASRRLEERQSALDELELQLfpqaGTLLHFLRKEAPdWEQSIGKVI 555

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1032 EEDRENRDD--PEEWgtskwrevEASLKQTISEKEVELEGIRRDLKEKTAAEEELQAVVQRMTRDLQSKTKQIDLLQEEV 1109
Cdd:pfam12128  556 SPELLHRTDldPEVW--------DGSVGGELNLYGVKLDLKRIDVPEWAASEEELRERLDKAEEALQSAREKQAAAEEQL 627

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1110 TENQATIQKLVTGTMDAGNGGSAApvketaassppgaggeehwkpelEGRILDLEKDKTQLQKKLQEALIARKA-ILKKA 1188
Cdd:pfam12128  628 VQANGELEKASREETFARTALKNA-----------------------RLDLRRLFDEKQSEKDKKNKALAERKDsANERL 684

                          490       500       510
                   ....*....|....*....|....*....|..
gi 1039751015 1189 QEKEKQLKEELREQKDAYHHLQGQFHEQNKEK 1220
Cdd:pfam12128  685 NSLEAQLKQLDKKHQAWLEEQKEQKREARTEK 716
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1595-2191 7.19e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 61.88  E-value: 7.19e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1595 EKHKELQKEYEVLlqsyenvsnEAERIQHVVESVRQEKQELyaklrSTESDKREREKQLQDAEQEMEEMKEKMRKfaKSK 1674
Cdd:COG1196    213 ERYRELKEELKEL---------EAELLLLKLRELEAELEEL-----EAELEELEAELEELEAELAELEAELEELR--LEL 276

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1675 QQKILELEEENDRLRAEAQPVGGTGESMEALLSSNSSLKEELEKITLEHKTLSKEFEALMAEKDALSEETRNLKLQVEAQ 1754
Cdd:COG1196    277 EELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEA 356

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1755 VLKQASLEATEKSDEpKDVIEEVTQAVVGKSQERDALSDSAKLEdseailmgdgakpgvsetfsshDDIKNYLQQLDQLK 1834
Cdd:COG1196    357 EAELAEAEEALLEAE-AELAEAEEELEELAEELLEALRAAAELA----------------------AQLEELEEAEEALL 413

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1835 GRIAELEMEKQKDRELSQALENEKNALLTQISAKDSELKLLEEEVTKRTTLNQQIQEELCRVTKLKETAEEEKDDLEERL 1914
Cdd:COG1196    414 ERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARL 493

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1915 mNQLAELNGSIGNYYQDVTDAQIKNEQ--LESEMRNLQRCVSELEEE---------KQQLVKEKTKVESEIRKEYMEKIQ 1983
Cdd:COG1196    494 -LLLLEAEADYEGFLEGVKAALLLAGLrgLAGAVAVLIGVEAAYEAAleaalaaalQNIVVEDDEVAAAAIEYLKAAKAG 572

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1984 GAQKGPANKSHAKELQELLREKQQEVKQLqkDCIRYLERISALEKTVKALEFVHTESQKDLDVTKGNLAQAVEHRKKAQA 2063
Cdd:COG1196    573 RATFLPLDKIRARAALAAALARGAIGAAV--DLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVT 650

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2064 ELSSFKILLDDTQSEAARVLADNLKLKKELQSNKESIKSQIKQKDEDLLRRLEQAEEKHRKEKKNMQEKLDALHREKAHV 2143
Cdd:COG1196    651 LEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQL 730

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*...
gi 1039751015 2144 EETLAEIQVSLTRKDQEMKELQGSLDSTLAQLAAFTKSMSSLQDDRDR 2191
Cdd:COG1196    731 EAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEA 778
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1158-1925 7.43e-09

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 62.00  E-value: 7.43e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1158 GRILDLEKDKTQLQKKLQEALIARKAILKKAQEKEKQLKE---ELREQKDAYHHLQGQFHEQNKEKENIADQLRQLQCQA 1234
Cdd:TIGR02168  232 LRLEELREELEELQEELKEAEEELEELTAELQELEEKLEElrlEVSELEEEIEELQKELYALANEISRLEQQKQILRERL 311

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1235 RESIDRQLPGTGQQEPGPPAPSLEGISLEDTEPASEsdlhaaqpsppgetaalQATVSVAQIQAQLKEMEVEKEELELKV 1314
Cdd:TIGR02168  312 ANLERQLEELEAQLEELESKLDELAEELAELEEKLE-----------------ELKEELESLEAELEELEAELEELESRL 374

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1315 SSIASELAKKSEEVLLLQDQINEQGLEIQNLKAASVEAQAHTELLKQELEsSQLKVAGLEHLKTLQPELDALHKHMGQKE 1394
Cdd:TIGR02168  375 EELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIE-ELLKKLEEAELKELQAELEELEEELEELQ 453

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1395 EEVNYLYGQLSEKEQTLTTVQTEMVEQERLIKALHTQLEMqAKEHEERLKQAQVEICELKKKPTELEEETNAKQQ----- 1469
Cdd:TIGR02168  454 EELERLEEALEELREELEEAEQALDAAERELAQLQARLDS-LERLQENLEGFSEGVKALLKNQSGLSGILGVLSElisvd 532

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1470 ----------LQRKLQAALISRKEALKENKSLQEQLSSARDAVERLTkSLADVESQVSVQN--QEKDAVLGKLTILQEER 1537
Cdd:TIGR02168  533 egyeaaieaaLGGRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLD-SIKGTEIQGNDREilKNIEGFLGVAKDLVKFD 611

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1538 DKLIAEMDRFLlenqSLSGSCESLKLALGGLTEDKEKLM-------------------EELESVRSSKMAESTEWQEKHK 1598
Cdd:TIGR02168  612 PKLRKALSYLL----GGVLVVDDLDNALELAKKLRPGYRivtldgdlvrpggvitggsAKTNSSILERRREIEELEEKIE 687

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1599 ELQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQELYAKLRSTESDKREREKQLQDAEQEMEEMKEKMRKFAKSKQQKI 1678
Cdd:TIGR02168  688 ELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELE 767

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1679 LELEEENDRLRAEAQPVGGTGESMEALLSSNSSLKEELEKITLEHKTLSKEFEAL-----MAEKDALSEETRNLKLQVEA 1753
Cdd:TIGR02168  768 ERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLrerleSLERRIAATERRLEDLEEQI 847

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1754 QVLKQASLEATEKSDEPKDVIEEVTQAVVGKSQERDALSDSAKLEDSEAILMGDGAKpgvsetfSSHDDIKNYLQQLDQL 1833
Cdd:TIGR02168  848 EELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELR-------ELESKRSELRRELEEL 920

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1834 KGRIAELEMEKQKdrelsqaLENEKNALLTQISAKDS-ELKLLEEEVTKRTTLNQQIQEELCRVT-KLKE------TAEE 1905
Cdd:TIGR02168  921 REKLAQLELRLEG-------LEVRIDNLQERLSEEYSlTLEEAEALENKIEDDEEEARRRLKRLEnKIKElgpvnlAAIE 993

                          810       820
                   ....*....|....*....|...
gi 1039751015 1906 EKDDLEER---LMNQLAELNGSI 1925
Cdd:TIGR02168  994 EYEELKERydfLTAQKEDLTEAK 1016
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 930-1635 1.14e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 61.11  E-value: 1.14e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  930 KTLKEQLNLLSRTEEATK-EQVEESGAGSSLKLGHDESGQEGLQQELELLRKESEQRKRKLQAALINRKELLQKVSQLEE 1008
Cdd:COG1196    216 RELKEELKELEAELLLLKlRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLA 295

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1009 ELAKVREDSRKEipfgeNERRKLEEDRENRDDPEEwgtSKWREVEASLKQTISEKEVELEGIRRDLKEKTAAEEELQAVV 1088
Cdd:COG1196    296 ELARLEQDIARL-----EERRRELEERLEELEEEL---AELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEAL 367

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1089 QRMTRDLQSKTKQIDLLQEEVTENQATIQklvtgtmdagnggsaapvketaassppgaggeehwkpELEGRILDLEKDKT 1168
Cdd:COG1196    368 LEAEAELAEAEEELEELAEELLEALRAAA-------------------------------------ELAAQLEELEEAEE 410

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1169 QLQKKLQEALIARKAILKKAQEKEKQLKEELREQKDAYHHLQGQFHEQNKEKENIADQLRQLQCQARESIDRQLPgtgqq 1248
Cdd:COG1196    411 ALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEE----- 485

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1249 epgppapslegislEDTEPASESDLHAAQPSPPGETAALQATVSVAQIQAQLKEMEVEKEELELKVSSIASELAkkseev 1328
Cdd:COG1196    486 --------------LAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALA------ 545

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1329 lllqdqineqGLEIQNLKAASVEAQAHTELLKQELESsqlKVAGLEHLKTLQPELDALHKHMGQKEEEVNYLYGQLSEKE 1408
Cdd:COG1196    546 ----------AALQNIVVEDDEVAAAAIEYLKAAKAG---RATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREAD 612

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1409 QTLTTVQTEMVEQERLIKALHT-QLEMQAKEHEERLKQAQVEICELKKKPTELEEETNAKQQLQRKLQAALISRKEAlKE 1487
Cdd:COG1196    613 ARYYVLGDTLLGRTLVAARLEAaLRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLA-EE 691

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1488 NKSLQEQLSSARDAVERLTKSLADVESQVSVQNQEKDAVLGKLTILQEERDKLIAEMDRFLLENQSLSGSCESLKLALGG 1567
Cdd:COG1196    692 ELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELER 771

                          650       660       670       680       690       700
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1039751015 1568 LTEDkeklMEELESVRSskMAEstewqEKHKELQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQEL 1635
Cdd:COG1196    772 LERE----IEALGPVNL--LAI-----EEYEELEERYDFLSEQREDLEEARETLEEAIEEIDRETRER 828
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1317-1841 5.89e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 58.79  E-value: 5.89e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1317 IASELAKKSEEVLLLQDQINEQGLEIQNLKAASVEAQAHTELLKQELESSQlkvAGLEHLKTLQPELDALHKHMGQKEEE 1396
Cdd:COG1196    251 LEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLE---QDIARLEERRRELEERLEELEEELAE 327

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1397 VNYLYGQLSEKEQTLTTVQTEMVEQERLIKALHTQLEMQAKEHEERLKQAQVEICELKKkptELEEETNAKQQLQRKLQA 1476
Cdd:COG1196    328 LEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAE---ELLEALRAAAELAAQLEE 404

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1477 ALISRKEALKENKSLQEQLSSARDAVERLTKSLADVESQVSVQNQEKDAVLGKLTILQEERDKLIAEMDRFLLENQSLSG 1556
Cdd:COG1196    405 LEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLE 484

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1557 SCESLKLALGGLTEDKEKLMEELESVRSSKMAEST--------EWQEKHKELQKEYEVLLQSY------ENVSNEAERIQ 1622
Cdd:COG1196    485 ELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLrglagavaVLIGVEAAYEAALEAALAAAlqnivvEDDEVAAAAIE 564

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1623 HVVESV--RQEKQELYAKLRSTESDKREREKQLQDAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEAQPVGGTGE 1700
Cdd:COG1196    565 YLKAAKagRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAG 644

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1701 SMEALLSSNSSLKEELEKITLEHKTLSKEFEALMAEKDALSEETRNLKLQVEAQVLKQASLEATEKSDEPKDVIEEVTQA 1780
Cdd:COG1196    645 RLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEE 724

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1039751015 1781 VVGKSQERDALSDSAKLEDSEAILMGDGAKPGVSEtfsshDDIKNYLQQLDQLKGRIAELE 1841
Cdd:COG1196    725 ALEEQLEAEREELLEELLEEEELLEEEALEELPEP-----PDLEELERELERLEREIEALG 780
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 683-1119 8.61e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 58.41  E-value: 8.61e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  683 HQGELERLKTQVLELETSLHTAEETYKRNLSEKVKEISSLTQLSEEVKESAEEARSTLAAVTEERDQllyqvkeldvLAE 762
Cdd:COG1196    293 LLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAE----------LAE 362

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  763 LRARVQELESSLAEAEKQRgldYESQRAQHNLLTEQIHSLSieakskdvKIEALQRELDGVQLQFCEQGTQMKTLQSQLE 842
Cdd:COG1196    363 AEEALLEAEAELAEAEEEL---EELAEELLEALRAAAELAA--------QLEELEEAEEALLERLERLEEELEELEEALA 431

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  843 AKEREVREGTERLRDISQEMEGLSQALSQKELEIAKMDQLLLEKQKDVETLQQTIQEKDQQVTELsfsmteKMVQLNEEK 922
Cdd:COG1196    432 ELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLL------LEAEADYEG 505

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  923 FSLGVEIKTLKEQLNLLS------RTEEATKEQVEESGAGSSLKLGHDESGQEGLQQeLELLRKESEQRKRKLQAALINR 996
Cdd:COG1196    506 FLEGVKAALLLAGLRGLAgavavlIGVEAAYEAALEAALAAALQNIVVEDDEVAAAA-IEYLKAAKAGRATFLPLDKIRA 584

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  997 KELLQKVSQLEEELAKVREDSRKEIPFGENERRKLEEDRENRDDPEEWGTSKWREVEASLKQTISEKEVELEGIRRDLKE 1076
Cdd:COG1196    585 RAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTG 664

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|...
gi 1039751015 1077 KTAAEEELQAVVQRMTRDLQSKTKQIDLLQEEVTENQATIQKL 1119
Cdd:COG1196    665 GSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEER 707
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 155-514 1.16e-07

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 58.14  E-value: 1.16e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  155 LQEKEKLISSLQAQLDqsEQASQLDKSSAEMEDfvlMKQQLQEKEELISTLQTQLSQTQAEQAAQlssmqqvvREKDARF 234
Cdd:TIGR02168  672 ILERRREIEELEEKIE--ELEEKIAELEKALAE---LRKELEELEEELEQLRKELEELSRQISAL--------RKDLARL 738

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  235 ETQVRLHEDELLQLvtqSDVETEMQQKLRVMQRKLEEHEEALLGRAQVVDLLQKELTSAEQRNQVLSQQLQLLEAEHNTL 314
Cdd:TIGR02168  739 EAEVEQLEERIAQL---SKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLL 815

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  315 KntmeTERQESKTLMEKVELEVAERKLSFHNLQEEMHQLQGQLERAGQAQADLETQYSALQQRHKTEMEEKTACILSLQK 394
Cdd:TIGR02168  816 N----EEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALAL 891

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  395 NEQELQSACAALKEENSKL--LQEKHDQAAESAQAMRQLEDQLQQKSKEISQFVNKpnlqknetASQTSLPDVNNEGDQA 472
Cdd:TIGR02168  892 LRSELEELSEELRELESKRseLRRELEELREKLAQLELRLEGLEVRIDNLQERLSE--------EYSLTLEEAEALENKI 963

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*.
gi 1039751015  473 VMEEtvASLQKRVVELENEKGAL----LLSSGELEELKAENEKLSS 514
Cdd:TIGR02168  964 EDDE--EEARRRLKRLENKIKELgpvnLAAIEEYEELKERYDFLTA 1007
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1823-2594 1.22e-07

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 58.06  E-value: 1.22e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1823 IKNYLQQLDQLKGRIAELEMEKQKDRELSQALENEKNALLTQISAKDSELKLLEEEVTKRttlnQQIQEELCRVTKLKET 1902
Cdd:pfam02463  281 KKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEEL----EKELKELEIKREAEEE 356

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1903 AEEEKDDLEERLMNQLAELNGSIGNYYQDVTDAQIKNEQLESEMRNLQRCVS---ELEEEKQQLVKEKTKVESEIRKEYM 1979
Cdd:pfam02463  357 EEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQlllELARQLEDLLKEEKKEELEILEEEE 436

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1980 EKIQGAQKGPANKSHAKELQELLREKQQEVKQLQKDcirylerisalektvkalefvhtesqkdldvtKGNLAQAVEHRK 2059
Cdd:pfam02463  437 ESIELKQGKLTEEKEELEKQELKLLKDELELKKSED--------------------------------LLKETQLVKLQE 484

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2060 KAQAELSSFKILLDDTQSEAARVLADNLKLKKELQSNKESIKSQIKQKDEDLLRRLEQAEEKHRKEKKNMQEKLDALHRE 2139
Cdd:pfam02463  485 QLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQ 564

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2140 KAHVEETLAEIQVSLTRKDQEMKELQGSLDSTLAQLAAfTKSMSSLQDDRDRVIDEAKKWERRFGDAIQTKEEEVRLKEE 2219
Cdd:pfam02463  565 KLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPI-LNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKA 643

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2220 NCIALKDQLRQMAIHMEELKITVSRLEHDKEIWESKAQTELQHHQKAYDKLQEENKELTSQLEDARQLYHDSKNELTKLE 2299
Cdd:pfam02463  644 KESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELL 723

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2300 SELKSLKDQTTDLNNSLEKCKEHENNLEGIIKQQEADIQNCKFSCEQLETDLAASReltsRLHDEINAKEQKIISLLSGK 2379
Cdd:pfam02463  724 ADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEE----REKTEKLKVEEEKEEKLKAQ 799

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2380 EEAIQLAVEELHQQHSKEIKELENLLSQEEEENVALEEENKRALEKTNQLTEALEAIKKESFEQKAQLDSFVKSMSSLQD 2459
Cdd:pfam02463  800 EEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEEL 879

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2460 DRDRIVsDYRQLEERHLSAILEKDQLIQDAAAENNKLKEEMRGLRSHMDDLNSENAKLDAELVQYRRDLNEVIAIKDSQQ 2539
Cdd:pfam02463  880 EEQKLK-DELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEE 958

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1039751015 2540 KQLLDAQLQQNKELRN-------ECTKLEERLKGLEAEKQSLQMSSDALQKEKQGLSKEIKN 2594
Cdd:pfam02463  959 EERNKRLLLAKEELGKvnlmaieEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQRLK 1020
PTZ00121 PTZ00121
MAEBL; Provisional
 965-1693 2.86e-07

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 56.69  E-value: 2.86e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  965 ESGQEGLQQELELLRKESEQRKRKLQAALINRKELLQKVSQLEEElAKVREDSRKEIPFGENERRKLEEDRENRDDPEEW 1044
Cdd:PTZ00121  1101 EEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEA-RKAEDAKRVEIARKAEDARKAEEARKAEDAKKAE 1179

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1045 GTSKWREVEASLKQTISEKEVELEGIRRDLKEKTAAE---EELQAVVQRMTRDLQSKTKQIDLLQEEVTENQATIQKLVT 1121
Cdd:PTZ00121  1180 AARKAEEVRKAEELRKAEDARKAEAARKAEEERKAEEarkAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEE 1259

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1122 GTMDAGNGGSAAPVKETAASSPPGAGGEEHWKPElEGRILDLEKDKTQLQKKLQEALIARKAiLKKAQEKEKQ---LKEE 1198
Cdd:PTZ00121  1260 ARMAHFARRQAAIKAEEARKADELKKAEEKKKAD-EAKKAEEKKKADEAKKKAEEAKKADEA-KKKAEEAKKKadaAKKK 1337

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1199 LREQKDAYHHLQGQFHEQNKEKENIADQLRQLQCQARESIDRQLPGTGQQEPGPPAPSLEGISLEDTEPASESDLHAAQP 1278
Cdd:PTZ00121  1338 AEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAK 1417

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1279 SPPGETAALQATVSVAQiqaqlkemeveKEELELKVSSIASELAKKSEEvlllqdqineqGLEIQNLKAASVEAQAHTEL 1358
Cdd:PTZ00121  1418 KKADEAKKKAEEKKKAD-----------EAKKKAEEAKKADEAKKKAEE-----------AKKAEEAKKKAEEAKKADEA 1475

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1359 LKQELESSQlkvagLEHLKTLQPELDALHKHMGQKEEEVNYLyGQLSEKEQTLTTVQTEMVEQERliKALHTQLEMQAKE 1438
Cdd:PTZ00121  1476 KKKAEEAKK-----ADEAKKKAEEAKKKADEAKKAAEAKKKA-DEAKKAEEAKKADEAKKAEEAK--KADEAKKAEEKKK 1547

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1439 HEERLKQAQVEICELKKKPTELEEETNAKQQLQRKLQAALISRKEALKENKSLQEQLSSARDAVERLTKSLADVESQVSV 1518
Cdd:PTZ00121  1548 ADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKK 1627

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1519 QNQEKDAVLGKLTILQEERDKliAEMDRFLLENQSLSGSCESLKLALGGLTEDKEKLMEELESVRSSKMAESTEWQEKHK 1598
Cdd:PTZ00121  1628 AEEEKKKVEQLKKKEAEEKKK--AEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAE 1705

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1599 ELQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQELYAKLRSTESDKREREKQLQDAEQEMEEMKEKMRKFAKSKQQki 1678
Cdd:PTZ00121  1706 ELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEE-- 1783

                          730
                   ....*....|....*
gi 1039751015 1679 lELEEENDRLRAEAQ 1693
Cdd:PTZ00121  1784 -ELDEEDEKRRMEVD 1797
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1938-2669 3.86e-07

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 56.13  E-value: 3.86e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1938 KNEQLESEMRNLQRCVSELEEEKQQLVKEKTKVESEIRKEY-MEKIQGAQKGPANKSHAKELQELLREKQQEVKQLQKDC 2016
Cdd:pfam02463  174 ALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQlKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEI 253

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2017 IRYLERISALEKTVKALEFVHTESQKDLDVTKGNLAQAVEHRKKAQAELSSFKILLDDTQSEAARVLADNLKLKKELQSN 2096
Cdd:pfam02463  254 ESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKE 333

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2097 KESIKSQIKQKDEDLLRRLEQAEEKhrkekknmqEKLDALHREKAHVEETLAEIQvsltRKDQEMKELQGSLDSTLAQLA 2176
Cdd:pfam02463  334 KEEIEELEKELKELEIKREAEEEEE---------EELEKLQEKLEQLEEELLAKK----KLESERLSSAAKLKEEELELK 400

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2177 AFTKSMSSLQDDRDRVIDEAKKWERRFGDAIQTKEEEVRLKEENCIALKDQLRQMAIHMEELKITVSRLEHDKEIWESKA 2256
Cdd:pfam02463  401 SEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLV 480

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2257 QTELQHHQKAYDKLQEENKELTSQLEDARQLYHDSKNELTKLESELKSLKdqTTDLNNSLEKCKEHENNLEGIIKQQEAD 2336
Cdd:pfam02463  481 KLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGR--LGDLGVAVENYKVAISTAVIVEVSATAD 558

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2337 IQNCKFSCEQLETDLAASRELTSRLHDEINAKEQKIISL-------LSGKEEAIQLAVEELHQQHSKEIKELENLLSQEE 2409
Cdd:pfam02463  559 EVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLeidpilnLAQLDKATLEADEDDKRAKVVEGILKDTELTKLK 638

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2410 EENVALEEENKRALEKTNQLTEALEAIKKESFEQKAQLDSFVKSMSSLQDdrdrivsdyrQLEERHLSAILEKDQLIQDA 2489
Cdd:pfam02463  639 ESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESE----------LAKEEILRRQLEIKKKEQRE 708

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2490 AAENNKLKEEMRGLRSHMDDLNSENAKLDAELVQYRRDLN----EVIAIKDSQQKQLLDAQLQQNKELRNECTKLEERLK 2565
Cdd:pfam02463  709 KEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEeeeeEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKV 788

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2566 GLEAEKQSLQMSSDALQKEKQGLSKEIKNLQTQLTALQEEGTLGVYHAQLKAKEEELQRLNMALSSSQKRTADLEEELVC 2645
Cdd:pfam02463  789 EEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEEL 868

                          730       740
                   ....*....|....*....|....
gi 1039751015 2646 VQKEATRKVSEIEDQLKKELKHLH 2669
Cdd:pfam02463  869 LQELLLKEEELEEQKLKDELESKE 892
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
2459-2738 6.48e-07

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 55.69  E-value: 6.48e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2459 DDRDRIVSDYrQLEERHLSAILEKDQLIQDAAAENNKLKEEMRGLRSHMDDLNSENAKLdAELVQYRRDLNEViaikDSQ 2538
Cdd:COG4913    593 DDRRRIRSRY-VLGFDNRAKLAALEAELAELEEELAEAEERLEALEAELDALQERREAL-QRLAEYSWDEIDV----ASA 666

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2539 QKQL--LDAQLQQNKELRNECTKLEERLKGLEAEKQSLQMSSDALQKEKQGLSKEIKNLQTQLTALQ---EEGTLGVYHA 2613
Cdd:COG4913    667 EREIaeLEAELERLDASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQdrlEAAEDLARLE 746

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2614 QLKAKEEELQRLNMALSSSQKRtADLEEELVCVQKEATRKVSEIEDQLKKELKHLHHDAGIMRNETETAEERVAELAR-- 2691
Cdd:COG4913    747 LRALLEERFAAALGDAVERELR-ENLEERIDALRARLNRAEEELERAMRAFNREWPAETADLDADLESLPEYLALLDRle 825

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2692 --DLVEMEQKLLT-VTKENKDLMAQIQafgrsmSSLQDSRDHATEELGDL 2738
Cdd:COG4913    826 edGLPEYEERFKElLNENSIEFVADLL------SKLRRAIREIKERIDPL 869
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1821-2454 1.09e-06

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 54.64  E-value: 1.09e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1821 DDIKNYLQQLDQLKGRIAELEMEKQKDRELSQALENEKNALLTQISAKDSELKLLEEEVTKRTTLNQQIQEELCRVTKLK 1900
Cdd:TIGR04523   89 DKLKKNKDKINKLNSDLSKINSEIKNDKEQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQK 168

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1901 ETAEEEKDDLEERLMNQLAELNGSIGNYYQDVTDAQI------KNEQLESEMRNLQRCVSELEEEKQQLVKEKTKVESEI 1974
Cdd:TIGR04523  169 EELENELNLLEKEKLNIQKNIDKIKNKLLKLELLLSNlkkkiqKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEI 248

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1975 rkeymekiqgaqkgpanKSHAKELQELLREKQQEVKQLQkdcirylerisalektvkalefvhtESQKDLDVTKGNLAQA 2054
Cdd:TIGR04523  249 -----------------SNTQTQLNQLKDEQNKIKKQLS-------------------------EKQKELEQNNKKIKEL 286

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2055 VEHRKKAQAELSsfkillddtqseaarvladNLKLKKELQSNKEsIKSQIKQKDEDlLRRLEQAEEKHRKEKKNMQEKLD 2134
Cdd:TIGR04523  287 EKQLNQLKSEIS-------------------DLNNQKEQDWNKE-LKSELKNQEKK-LEEIQNQISQNNKIISQLNEQIS 345

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2135 ALHREKAHVEETLAEIQVSLTRKDQEMKELQGSLDSTLAQLAAFTKSMSSLQddrdRVIDEAKKWERRFGDAIQTKEEEV 2214
Cdd:TIGR04523  346 QLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLE----SKIQNQEKLNQQKDEQIKKLQQEK 421

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2215 RLKEENCIALKDQLRQMAIHMEELKITvsrlEHDKEIWESKAQTELQHHQKAYDKLQEENKELTSQLEDARQLYHDSKNE 2294
Cdd:TIGR04523  422 ELLEKEIERLKETIIKNNSEIKDLTNQ----DSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKE 497

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2295 LTKLESELKSLKDQTTDLNNSLEKCKEHENNLEGIIKQQEADIQNCKFSCEQLETDLAasrelTSRLHDEINAKEQKIIS 2374
Cdd:TIGR04523  498 LKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDFELK-----KENLEKEIDEKNKEIEE 572

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2375 LLSGKE--EAIQLAVEELHQQHSKEIKELENLLSQEEEENVALeeenKRALEKTNQLTEALEAIKKESFEQKAQLDSFVK 2452
Cdd:TIGR04523  573 LKQTQKslKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSL----EKELEKAKKENEKLSSIIKNIKSKKNKLKQEVK 648


                   ..
gi 1039751015 2453 SM 2454
Cdd:TIGR04523  649 QI 650
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
731-996 1.13e-06

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 54.64  E-value: 1.13e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  731 ESAEEARSTLAAVTEE--RDQLLYQVKELD-VLAELRARVQELESSLAEAEKQrgldYESQRAQHNLLteqihSLSIEAK 807
Cdd:COG3206    145 PDPELAAAVANALAEAylEQNLELRREEARkALEFLEEQLPELRKELEEAEAA----LEEFRQKNGLV-----DLSEEAK 215

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  808 SKDVKIEALQRELDGVQLQFCEQGTQMKTLQSQLEAKEREVREGTErlrdiSQEMEGLSQALSQKELEIAKMDQLLLEKQ 887
Cdd:COG3206    216 LLLQQLSELESQLAEARAELAEAEARLAALRAQLGSGPDALPELLQ-----SPVIQQLRAQLAELEAELAELSARYTPNH 290

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  888 KDVETLQQTIQEKDQQVTElsfsmtekmvQLNEEKFSLGVEIKTLKEQLNLLSRTEEATKEQVEESGAgsslklghDESG 967
Cdd:COG3206    291 PDVIALRAQIAALRAQLQQ----------EAQRILASLEAELEALQAREASLQAQLAQLEARLAELPE--------LEAE 352

                          250       260
                   ....*....|....*....|....*....
gi 1039751015  968 QEGLQQELELLRKESEQRKRKLQAALINR 996
Cdd:COG3206    353 LRRLEREVEVARELYESLLQRLEEARLAE 381
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 47-529 1.16e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 54.56  E-value: 1.16e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015   47 ESTQEDALHRLAEAEKLVVELKDIISQKDVQLQQKDEALQEEKKAAENKIKKIKlHAKAKIMSLNKHMEEIktqggaalp 126
Cdd:COG1196    252 EAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIA-RLEERRRELEERLEEL--------- 321

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  127 pEAQAEELSKHNKSSTEEEMEIEKIKHELQEKEKLISSLQAQLDQSEQASQLDKSSAEMEDFVLMKQQLQEKEELISTLQ 206
Cdd:COG1196    322 -EEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAA 400

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  207 TQLSQTQAEQAAQlssmqqvvrEKDARFETQVRLHEDELLQLVTQSDVEtemQQKLRVMQRKLEEHEEALLGRAQVVDLL 286
Cdd:COG1196    401 QLEELEEAEEALL---------ERLERLEEELEELEEALAELEEEEEEE---EEALEEAAEEEAELEEEEEALLELLAEL 468

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  287 QKELTSAEQRNQVLSQQLQLLEAEHNTLKNTMETERQESKTLMEKVELEVAERklsfhnLQEEMHQLQGQLERAGQAQAD 366
Cdd:COG1196    469 LEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRG------LAGAVAVLIGVEAAYEAALEA 542

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  367 LETqySALQQRHKTEMEEKTACILSLQKNEQELQSACAALKEENSKLLQEKHDQAAEsAQAMRQLEDQLQQKSKEISQFV 446
Cdd:COG1196    543 ALA--AALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAI-GAAVDLVASDLREADARYYVLG 619

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  447 NkpnlqkneTASQTSLPDVNNEGDQAVMEETVASLQKRVVELENEKGALLLSSGELEELKAENEKLSSRITLLEAQNRAG 526
Cdd:COG1196    620 D--------TLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEE 691


                   ...
gi 1039751015  527 EAD 529
Cdd:COG1196    692 ELE 694
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 794-1015 1.30e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 53.61  E-value: 1.30e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  794 LLTEQIHSLSIEAKSKDVKIEALQRELDGVQLQFCEQGTQMKTLQSQLEAKEREVREGTERLRDISQEMEGLSQALSQKE 873
Cdd:COG4942     10 LLALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELE 89

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  874 LEIAKMDQLLLEKQKDVETLQQTIQEKDQQVTEL----------SFSMTEKMVQLNEEKFSLGVEIKTLKEQLNLLSRTE 943
Cdd:COG4942     90 KEIAELRAELEAQKEELAELLRALYRLGRQPPLAlllspedfldAVRRLQYLKYLAPARREQAEELRADLAELAALRAEL 169

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1039751015  944 EATKEQVEESGAGSSLKLGHDESGQEGLQQELELLRKESEQRKRKLQAALINRKELLQKVSQLEEELAKVRE 1015
Cdd:COG4942    170 EAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAE 241
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1331-1773 1.41e-06

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 54.35  E-value: 1.41e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1331 LQDQINEQGLEIQNL----KAASVEAQAHTEllkQELESSQLKVAGLEHLKTLQPELDALHKHMGQKEEEVNYLYGQLSE 1406
Cdd:pfam15921  417 LRRELDDRNMEVQRLeallKAMKSECQGQME---RQMAAIQGKNESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLES 493

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1407 KEQTLTTVQTEMVEQERLIKALHTQLEMQAKEHEERLKQAQveicelkkkptELEEETNAKQQLQRKLQAALISRKEALK 1486
Cdd:pfam15921  494 SERTVSDLTASLQEKERAIEATNAEITKLRSRVDLKLQELQ-----------HLKNEGDHLRNVQTECEALKLQMAEKDK 562

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1487 ENKSLQEQLSSARDAV---ERLTKSLADVESQVSVQNQEKDAVLGKLTILQEERDKLIAEmdrflLENQSLSGSCESLKL 1563
Cdd:pfam15921  563 VIEILRQQIENMTQLVgqhGRTAGAMQVEKAQLEKEINDRRLELQEFKILKDKKDAKIRE-----LEARVSDLELEKVKL 637

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1564 ALGGltEDKEKLMEELESVRSSKMAESTEWQEKHKELQKEYEVLLQSYENVSNEAERIQHvvesvrqekqELYAKLRSTE 1643
Cdd:pfam15921  638 VNAG--SERLRAVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMETTTN----------KLKMQLKSAQ 705

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1644 SDKREREKQLQDAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEAQPVGGTGESMEALLSSNSSLKEELEKITLEH 1723
Cdd:pfam15921  706 SELEQTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATEK 785

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1724 KTLSKEFEALMAEKDALSEETRNLKLQVEAQVLKQASLEATEKSDEPKDV 1773
Cdd:pfam15921  786 NKMAGELEVLRSQERRLKEKVANMEVALDKASLQFAECQDIIQRQEQESV 835
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 2190-3036 1.64e-06

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 54.35  E-value: 1.64e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2190 DRVIDE----AKKWERRFGDAIQTKEEEVRLKEENCIALKDQLRQMAIHMEELKITVSRLEHDKEIWESKAQTELQHHQK 2265
Cdd:pfam15921   77 ERVLEEyshqVKDLQRRLNESNELHEKQKFYLRQSVIDLQTKLQEMQMERDAMADIRRRESQSQEDLRNQLQNTVHELEA 156

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2266 AYDKLQEENKELTSQLEDARQLYHDSKNELTKLESELKSLKDQttdlnnSLEKCKEHENNLEGIIKQQEADIQNCkfsCE 2345
Cdd:pfam15921  157 AKCLKEDMLEDSNTQIEQLRKMMLSHEGVLQEIRSILVDFEEA------SGKKIYEHDSMSTMHFRSLGSAISKI---LR 227

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2346 QLETDLaasreltSRLHDEINAKEQKIISLLSGKEEAIQLaveeLHQQHSKEIkelENLLSQEEEENVALEEENKRALEK 2425
Cdd:pfam15921  228 ELDTEI-------SYLKGRIFPVEDQLEALKSESQNKIEL----LLQQHQDRI---EQLISEHEVEITGLTEKASSARSQ 293

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2426 TNQLTEALEAIKKESFEQKAQldsFVKSMSSLQDDRDRIVSDYRQLEERHLSAIlekDQLIQDAAAENNKLKEEmrglRS 2505
Cdd:pfam15921  294 ANSIQSQLEIIQEQARNQNSM---YMRQLSDLESTVSQLRSELREAKRMYEDKI---EELEKQLVLANSELTEA----RT 363

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2506 HMDDLNSENAKLDAELVQYRRDLNeviaikdsQQKQLLDAQLQQNKELRNECTkleerlkgleaekqSLQMSSDALQKEK 2585
Cdd:pfam15921  364 ERDQFSQESGNLDDQLQKLLADLH--------KREKELSLEKEQNKRLWDRDT--------------GNSITIDHLRREL 421

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2586 QGLSKEIKNLQTQLTALQEEgtlgvYHAQLKAKEEELQRLNMALSSSQKRTADLEEelvcvQKEATRKVSEIEDQLKKEL 2665
Cdd:pfam15921  422 DDRNMEVQRLEALLKAMKSE-----CQGQMERQMAAIQGKNESLEKVSSLTAQLES-----TKEMLRKVVEELTAKKMTL 491

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2666 khlhhdagimrnetETAEERVAELARDLVEMEQKLltvtkenkdlmaqiqafgrsmsslqdsrDHATEELGDLKKKYDAS 2745
Cdd:pfam15921  492 --------------ESSERTVSDLTASLQEKERAI----------------------------EATNAEITKLRSRVDLK 529

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2746 LKELAQLKEwqdssrEGDVLsqaafplstsENVLSRLEKLNQQLTSKDEQLLHLSSELESSHNQVQSISKAMTSLQNERD 2825
Cdd:pfam15921  530 LQELQHLKN------EGDHL----------RNVQTECEALKLQMAEKDKVIEILRQQIENMTQLVGQHGRTAGAMQVEKA 593

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2826 RLWSE-------LEKFRKSEEGKQ-RAAAPSAASSPAEVQSLK---------KAMSSLQNDRDRLLKELKNLQQQYLQMS 2888
Cdd:pfam15921  594 QLEKEindrrleLQEFKILKDKKDaKIRELEARVSDLELEKVKlvnagserlRAVKDIKQERDQLLNEVKTSRNELNSLS 673

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2889 QEMTELRplkaqlQESQDQTKALQVMEEELRQENLSWQHELRQLRMEKNSWE---LHERRMKEQFLMAISDKDQQLGHLQ 2965
Cdd:pfam15921  674 EDYEVLK------RNFRNKSEEMETTTNKLKMQLKSAQSELEQTRNTLKSMEgsdGHAMKVAMGMQKQITAKRGQIDALQ 747

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1039751015 2966 S----LLRELRSSSQAQILSTQYQRQASPETSASLDGSQKLVYETELLRTQLNDSLKEIHQKELRIQQLNSKFSQ 3036
Cdd:pfam15921  748 SkiqfLEEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANMEVALDKASLQFAE 822
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
2090-2665 1.81e-06

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 53.91  E-value: 1.81e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2090 KKELQSNKESIKSQIKQKDEDLLRRLEQAEEKhRKEKKNMQEKLDALHREKAHVEET---LAEIQVSLTRKDQEMKELQG 2166
Cdd:PRK03918   181 LEKFIKRTENIEELIKEKEKELEEVLREINEI-SSELPELREELEKLEKEVKELEELkeeIEELEKELESLEGSKRKLEE 259

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2167 SLDSTLAQLAAFTKSMSSLQDDRDRVID---EAKKWERRFGDAIQTKEEEVRLKEENCIaLKDQLRQMAIHMEELKITVS 2243
Cdd:PRK03918   260 KIRELEERIEELKKEIEELEEKVKELKElkeKAEEYIKLSEFYEEYLDELREIEKRLSR-LEEEINGIEERIKELEEKEE 338

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2244 RLEhdkeiWESKAQTELQHHQKAYDKLQEENKELTSQLEDARQLYHDSKN-ELTKLESELKSLKDQTTDLNNSLEKCKEH 2322
Cdd:PRK03918   339 RLE-----ELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGlTPEKLEKELEELEKAKEEIEEEISKITAR 413

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2323 ENNLEGIIKQQEADIQNCKFS------CEQLETDlAASRELTSRLHDEINAKEQKIISLLSGKEEAIQLAVE-------- 2388
Cdd:PRK03918   414 IGELKKEIKELKKAIEELKKAkgkcpvCGRELTE-EHRKELLEEYTAELKRIEKELKEIEEKERKLRKELRElekvlkke 492

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2389 -ELHQQHS--KEIKELENLLSQEEEENVALEEENKRAL-EKTNQLTEALEAIKKESFEQKAQLDSFVKSMSSLQDDRDRI 2464
Cdd:PRK03918   493 sELIKLKElaEQLKELEEKLKKYNLEELEKKAEEYEKLkEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEEL 572

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2465 VSDYRQLEERHLSAILEKDQLIQDAAAENNKLKEeMRGLRSHMDDLNSENAKLDAELVQYRRDLNEVIAIKDSQQKQLLD 2544
Cdd:PRK03918   573 AELLKELEELGFESVEELEERLKELEPFYNEYLE-LKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEE 651

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2545 AQLQQNKE----LRNECTKLEERLKGLEAEKQSlqmssdaLQKEKQGLSKEIKNLQTQLTALQEegtlgvyhaqlkaKEE 2620
Cdd:PRK03918   652 LEKKYSEEeyeeLREEYLELSRELAGLRAELEE-------LEKRREEIKKTLEKLKEELEEREK-------------AKK 711

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*
gi 1039751015 2621 ELQRLNMALSSSQKRTADLEEELVCVQKEATRKVSEIEDQLKKEL 2665
Cdd:PRK03918   712 ELEKLEKALERVEELREKVKKYKALLKERALSKVGEIASEIFEEL 756
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 810-1747 2.00e-06

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 53.92  E-value: 2.00e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  810 DVKIEALQRELDGVQLQFCEQGTQMKTLQSQLE--AKEREVREGTERLRDISQEMEGLSQALSQKELE--IAKMDQLLLE 885
Cdd:TIGR02169  169 DRKKEKALEELEEVEENIERLDLIIDEKRQQLErlRREREKAERYQALLKEKREYEGYELLKEKEALErqKEAIERQLAS 248

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  886 KQKDVETLQQTIQEKDQQVTELSFSMTEKMVQLN----EEKFSLGVEIKTLKEQLNLLSRTEEATKEQVEESGAgsslKL 961
Cdd:TIGR02169  249 LEEELEKLTEEISELEKRLEEIEQLLEELNKKIKdlgeEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEE----RL 324

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  962 GHDESGQEGLQQELELLRKESEQ---RKRKLQAALINRKE----LLQKVSQLEEELAKVRE---DSRKEIPFGENERRKL 1031
Cdd:TIGR02169  325 AKLEAEIDKLLAEIEELEREIEEerkRRDKLTEEYAELKEeledLRAELEEVDKEFAETRDelkDYREKLEKLKREINEL 404

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1032 EEDRENRDDPEEWGTSKWREVE---ASLKQTISEKEVELEGIRRDLKEKTAAEEELQAVVQRMTRDLQSKTKQIDLLQEE 1108
Cdd:TIGR02169  405 KRELDRLQEELQRLSEELADLNaaiAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKE 484

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1109 VTENQATIQKLVTGTMDAGNG-GSAAPVKETAASSPPGaggeehwkpeLEGRILDLEKDKTQLQKKLQEALIAR-KAILK 1186
Cdd:TIGR02169  485 LSKLQRELAEAEAQARASEERvRGGRAVEEVLKASIQG----------VHGTVAQLGSVGERYATAIEVAAGNRlNNVVV 554

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1187 KAQEKEKQLKEELREQKDAyhhlQGQFHEQNKEKeniadqlrqlqcqaresiDRQLPGTGQQEPGPPAPSLEGISLEDT- 1265
Cdd:TIGR02169  555 EDDAVAKEAIELLKRRKAG----RATFLPLNKMR------------------DERRDLSILSEDGVIGFAVDLVEFDPKy 612

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1266 EPASesdlhaaqpsppgeTAALQATVSVAQIQAqlkemevekeelelkvssiASELAKKSEEVLLLQDQINEQGLEIQNL 1345
Cdd:TIGR02169  613 EPAF--------------KYVFGDTLVVEDIEA-------------------ARRLMGKYRMVTLEGELFEKSGAMTGGS 659

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1346 KAASVEAQAHTELLKQELESSqlkvaglEHLKTLQPELDALHKHMGQKEEEVNYLYGQLSEKEQTLTTVQTEMveqeRLI 1425
Cdd:TIGR02169  660 RAPRGGILFSRSEPAELQRLR-------ERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEI----EQL 728

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1426 KALHTQLEMQAKEHEERLKQAQVEICELKKKPTELEEETNAKQQLQRKLQAAL--ISRKEALKENKSLQEQLSSARDAVE 1503
Cdd:TIGR02169  729 EQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALndLEARLSHSRIPEIQAELSKLEEEVS 808

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1504 RLTKSLADVEsqvsvqnqekdavlgkltilqeerdkliAEMDRFLLENQSLsgsceslklalggltedkEKLMEELESVR 1583
Cdd:TIGR02169  809 RIEARLREIE----------------------------QKLNRLTLEKEYL------------------EKEIQELQEQR 842

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1584 SskmaestEWQEKHKELQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQELYAKLRSTESDKREREKQLQDAEQEMEEM 1663
Cdd:TIGR02169  843 I-------DLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKK 915

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1664 KEKMRKFAKSKQQKILELEEENDRLRAEAQPVGGT-------------GESMEALLSSNSSLKEELEKITLEHKTLSKEF 1730
Cdd:TIGR02169  916 RKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEElsledvqaelqrvEEEIRALEPVNMLAIQEYEEVLKRLDELKEKR 995

                          970
                   ....*....|....*..
gi 1039751015 1731 EALMAEKDALSEETRNL 1747
Cdd:TIGR02169  996 AKLEEERKAILERIEEY 1012
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
2112-2710 2.10e-06

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 53.91  E-value: 2.10e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2112 LRRLEQAEEKHRKEKKNMQEKLDALHRE---KAHVEETLAEIQVSLTRKDQEMKELQGSLDSTLAQLAAFTKSMSSLQDD 2188
Cdd:PRK03918   157 LDDYENAYKNLGEVIKEIKRRIERLEKFikrTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEEL 236

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2189 RDRVIDEAKKWERRFGDAiqtKEEEVRLKEenciaLKDQLRQMAIHMEELKITVSRLEhdkeiweskaqtELQHHQKAYD 2268
Cdd:PRK03918   237 KEEIEELEKELESLEGSK---RKLEEKIRE-----LEERIEELKKEIEELEEKVKELK------------ELKEKAEEYI 296

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2269 KLQEENKELTSQLEDArqlyhdsKNELTKLESELKSLKDQTTDLNNSLEKCKEHENNLEGIIKQQEAdIQNCKFSCEQLE 2348
Cdd:PRK03918   297 KLSEFYEEYLDELREI-------EKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEE-LEERHELYEEAK 368

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2349 TDLAASRELTSRLHDEINAKEQKIISLLSGKEEAIQLAVEELHQqhskEIKELENLLSQEEEENVALEEENKRALEKTNQ 2428
Cdd:PRK03918   369 AKKEELERLKKRLTGLTPEKLEKELEELEKAKEEIEEEISKITA----RIGELKKEIKELKKAIEELKKAKGKCPVCGRE 444

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2429 LTEAleaikkesfEQKAQLDSFVKSMSSLQDDRDRIVSDYRQLEERHLSaiLEKDQLIQDAAAENNKLKEEMRGLRSHMD 2508
Cdd:PRK03918   445 LTEE---------HRKELLEEYTAELKRIEKELKEIEEKERKLRKELRE--LEKVLKKESELIKLKELAEQLKELEEKLK 513

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2509 DLNSENAKLDAElvQYRRDLNEVIAIKdSQQKQLLDaQLQQNKELRNECTKLEERLKGLEAEKQSLQ--------MSSDA 2580
Cdd:PRK03918   514 KYNLEELEKKAE--EYEKLKEKLIKLK-GEIKSLKK-ELEKLEELKKKLAELEKKLDELEEELAELLkeleelgfESVEE 589

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2581 LQKEKQGLSK------EIKNLQTQLTALQEEgtLGVYHAQLKAKEEELQRLNMALSSSQKRtadLEEELVCVQKEATRKV 2654
Cdd:PRK03918   590 LEERLKELEPfyneylELKDAEKELEREEKE--LKKLEEELDKAFEELAETEKRLEELRKE---LEELEKKYSEEEYEEL 664

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1039751015 2655 SEIEDQLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLTVTKENKDL 2710
Cdd:PRK03918   665 REEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKAKKELEKLEKAL 720
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 686-1109 2.21e-06

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 53.97  E-value: 2.21e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  686 ELERLKTQVLELETSLHTAEETYKRNLsekvkeissltqlsEEVKESAEEARSTLAAVTEERDQLLYQVKELD-----VL 760
Cdd:pfam15921  318 QLSDLESTVSQLRSELREAKRMYEDKI--------------EELEKQLVLANSELTEARTERDQFSQESGNLDdqlqkLL 383

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  761 AELRARVQELesSLAEAEKQRGLDYESQRA-QHNLLTEQIHSLSIEAKSKDVKIEALQRELDGvqlqfcEQGTQMKTLQS 839
Cdd:pfam15921  384 ADLHKREKEL--SLEKEQNKRLWDRDTGNSiTIDHLRRELDDRNMEVQRLEALLKAMKSECQG------QMERQMAAIQG 455

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  840 QLEAKER------EVREGTERLRDISQEMEGLSQALSQKELEIAKMDQLLLEKQKDVETLQQTIQEKDQQVtELSFSMTE 913
Cdd:pfam15921  456 KNESLEKvssltaQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEATNAEITKLRSRV-DLKLQELQ 534

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  914 KMVQLNEEKFSLGVEIKTLKEQLNLLSRTEEATKEQVEESgagsSLKLGHDESGQEGLQQELELLRKESEQRKRKLQAAL 993
Cdd:pfam15921  535 HLKNEGDHLRNVQTECEALKLQMAEKDKVIEILRQQIENM----TQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQEFK 610

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  994 INR-------KELLQKVSQLEEELAKV-----------------REDSRKEIPFGENERRKLEED-----RENRDDPEEW 1044
Cdd:pfam15921  611 ILKdkkdakiRELEARVSDLELEKVKLvnagserlravkdikqeRDQLLNEVKTSRNELNSLSEDyevlkRNFRNKSEEM 690

                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1039751015 1045 GTSKWReveasLKQTISEKEVELEGIRRDLKEKTAAEEELQAVVQRMTRDLQSKTKQIDLLQEEV 1109
Cdd:pfam15921  691 ETTTNK-----LKMQLKSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKI 750
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 1406-2210 2.84e-06

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 53.30  E-value: 2.84e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1406 EKEQTLTTVQTEMVE--QERLIKALHTQLEMQAKEHEERLKQAQVEICELKKKPTELEEETNAKQQLQRKLQAALISRKE 1483
Cdd:pfam12128  190 SKEGKFRDVKSMIVAilEDDGVVPPKSRLNRQQVEHWIRDIQAIAGIMKIRPEFTKLQQEFNTLESAELRLSHLHFGYKS 269

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1484 ALKENKSLQEQLSSARDAVERLTKSL-ADVESQVSVQNQEKDAVLGKLTILQEERDKLIAEMDRFLLENqslsgsCESLK 1562
Cdd:pfam12128  270 DETLIASRQEERQETSAELNQLLRTLdDQWKEKRDELNGELSAADAAVAKDRSELEALEDQHGAFLDAD------IETAA 343

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1563 LALggltedkeklmEELESVRS--SKMAESTEWQE-KHKELQKEYEVLLQsyeNVSNEAERIQHVVESVRQEKQELYAKL 1639
Cdd:pfam12128  344 ADQ-----------EQLPSWQSelENLEERLKALTgKHQDVTAKYNRRRS---KIKEQNNRDIAGIKDKLAKIREARDRQ 409

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1640 RSTESDKRER-EKQLQDaeqemeEMKEKMRKFAKSKQQKILELEEENDRLrAEAQPVGGTGESMEALLSSNSSLKEELEK 1718
Cdd:pfam12128  410 LAVAEDDLQAlESELRE------QLEAGKLEFNEEEYRLKSRLGELKLRL-NQATATPELLLQLENFDERIERAREEQEA 482

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1719 ITLEHKTLSKEFEALMAEKDALSEETRNLKLQVEAQVLKQASLEaTEKSDEPKDVIEEVTQAVVGKSQERDALSDSAKLE 1798
Cdd:pfam12128  483 ANAEVERLQSELRQARKRRDQASEALRQASRRLEERQSALDELE-LQLFPQAGTLLHFLRKEAPDWEQSIGKVISPELLH 561

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1799 DSEAILMGDGAKPGVSETFSS------HDDIKNYLQQLDQLKGRIAELEMEKQKDRELSQALENEknalLTQISAKDSEL 1872
Cdd:pfam12128  562 RTDLDPEVWDGSVGGELNLYGvkldlkRIDVPEWAASEEELRERLDKAEEALQSAREKQAAAEEQ----LVQANGELEKA 637

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1873 KLleEEVTKRTTLnQQIQEELCRVT--------KLKETAEEEKDDLEERLMNQLAELNgSIGNYYQDVTdAQIKNEQLES 1944
Cdd:pfam12128  638 SR--EETFARTAL-KNARLDLRRLFdekqsekdKKNKALAERKDSANERLNSLEAQLK-QLDKKHQAWL-EEQKEQKREA 712

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1945 EMRNLQRCVSELEEEKQQLVKEKTKVESEirkeymekiqgaqkgpaNKSHAKELQELLREKQQEVKQLQKDCirylERIS 2024
Cdd:pfam12128  713 RTEKQAYWQVVEGALDAQLALLKAAIAAR-----------------RSGAKAELKALETWYKRDLASLGVDP----DVIA 771

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2025 ALEKTVKalefvhtesqkdldvtkgNLAQAVEHRKKAQAELSSFKILLDDTQSEAARVLADNLklkKELQSNKESIKSQI 2104
Cdd:pfam12128  772 KLKREIR------------------TLERKIERIAVRRQEVLRYFDWYQETWLQRRPRLATQL---SNIERAISELQQQL 830

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2105 KQKDEDLLRRLeQAEEKHRKEKKNMQEKLDALHREKAHVEETLAEIQVsltrkDQEMKELQGSLDSTLAQLaaftksmSS 2184
Cdd:pfam12128  831 ARLIADTKLRR-AKLEMERKASEKQQVRLSENLRGLRCEMSKLATLKE-----DANSEQAQGSIGERLAQL-------ED 897

                          810       820
                   ....*....|....*....|....*.
gi 1039751015 2185 LQDDRDRVIDEAKKWERRFGDAIQTK 2210
Cdd:pfam12128  898 LKLKRDYLSESVKKYVEHFKNVIADH 923
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 1836-2598 3.09e-06

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 53.51  E-value: 3.09e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1836 RIAELEMEKQKDRELSQALENEKNALLTQISAKDSELKLLEEEVTKRTTLNQQIQEELcrvtklkETAEEEKDDLEERLM 1915
Cdd:TIGR00606  320 ELVDCQRELEKLNKERRLLNQEKTELLVEQGRLQLQADRHQEHIRARDSLIQSLATRL-------ELDGFERGPFSERQI 392

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1916 NQLAELNGSiGNYYQDVTDAQIKNEqLESEMRNLQRCVSELEEEKQQL---VKEKTKVESEIRKEYMEKIQGAQKGPANK 1992
Cdd:TIGR00606  393 KNFHTLVIE-RQEDEAKTAAQLCAD-LQSKERLKQEQADEIRDEKKGLgrtIELKKEILEKKQEELKFVIKELQQLEGSS 470

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1993 SHAKELQELLREKQQEVKQLQKDcirylerisALEKTVKALEFVHTESQKDLDVTKGNLAQAVEHRKKAQAELSSFKILL 2072
Cdd:TIGR00606  471 DRILELDQELRKAERELSKAEKN---------SLTETLKKEVKSLQNEKADLDRKLRKLDQEMEQLNHHTTTRTQMEMLT 541

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2073 DDTQSEAARV-------------LADNLKLKKELQSNKESIKSQIKQKDEDL------LRRLEQAEEKHRKEKKNMQEKL 2133
Cdd:TIGR00606  542 KDKMDKDEQIrkiksrhsdeltsLLGYFPNKKQLEDWLHSKSKEINQTRDRLaklnkeLASLEQNKNHINNELESKEEQL 621

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2134 DALHREKAHVEETLAEiQVSLTRKDQEMKELQGSLDSTLAQLAAFTKSMSSLQDDRDRVIDEAKKwerrfgdAIQTKEEe 2213
Cdd:TIGR00606  622 SSYEDKLFDVCGSQDE-ESDLERLKEEIEKSSKQRAMLAGATAVYSQFITQLTDENQSCCPVCQR-------VFQTEAE- 692

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2214 vrlKEENCIALKDQLRQMAIHMEELKITVSRLEHDKEIWESKA---QTELQHHQKAYDKLQEENKELTSQLEDARQLYHD 2290
Cdd:TIGR00606  693 ---LQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLApgrQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEE 769

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2291 SKNELTKLESELKSLKDQTTDLNnSLEKCKEHENNLEGIIKQQEADIQ-----------NCKFSCEQLETDLAASR-ELT 2358
Cdd:TIGR00606  770 QETLLGTIMPEEESAKVCLTDVT-IMERFQMELKDVERKIAQQAAKLQgsdldrtvqqvNQEKQEKQHELDTVVSKiELN 848

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2359 SRLHDEINAKEQKIISLLSG-KEEAIQL--------AVEELHQQHSKEIKELENLLSQEEEENVALEEENKRALEKTNQL 2429
Cdd:TIGR00606  849 RKLIQDQQEQIQHLKSKTNElKSEKLQIgtnlqrrqQFEEQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEEL 928

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2430 TEALEAIKKESFEQ----KAQLDSFVKSMSSLQDDRDRIVSDYRQLEERHLSAILEKdqlIQDAAAENNKLKEEMRGLRS 2505
Cdd:TIGR00606  929 ISSKETSNKKAQDKvndiKEKVKNIHGYMKDIENKIQDGKDDYLKQKETELNTVNAQ---LEECEKHQEKINEDMRLMRQ 1005

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2506 HMDDLNSENAKLDAELVQYRRDlNEVIAIKDSQQKQLLDAQLQQNKELRNECTKLEERLKGLEAEKQSLQMSSDALQKEK 2585
Cdd:TIGR00606 1006 DIDTQKIQERWLQDNLTLRKRE-NELKEVEEELKQHLKEMGQMQVLQMKQEHQKLEENIDLIKRNHVLALGRQKGYEKEI 1084

                          810
                   ....*....|...
gi 1039751015 2586 QGLSKEIKNLQTQ 2598
Cdd:TIGR00606 1085 KHFKKELREPQFR 1097
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1316-1966 3.33e-06

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 53.10  E-value: 3.33e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1316 SIASELAKKSEEVLLLQDQINEQGLEIQNLKAASVEAQAHTELLKQELESSQLKVAGL-EHLKTLQPELDALHKHMGQKE 1394
Cdd:TIGR04523   44 TIKNELKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLnSDLSKINSEIKNDKEQKNKLE 123

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1395 EEVNYLYGQLSEKEQTLTTVQTEMVEQERLIKALHTQLEMQAKEHEERLKQAQVEICELKKKPTELeeeTNAKQQLqRKL 1474
Cdd:TIGR04523  124 VELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNI---DKIKNKL-LKL 199

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1475 QAALISRKEALKENKSLQEQLSSARDAVERLTKSLADVESQVSVQNQEKDAVLGKLTILQEERDKLIAEMDRFLLEnqsl 1554
Cdd:TIGR04523  200 ELLLSNLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKE---- 275

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1555 sgsCESLKLALGGLTEDKEKLMEELESVRSSKMaestewQEKHKELQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQE 1634
Cdd:TIGR04523  276 ---LEQNNKKIKELEKQLNQLKSEISDLNNQKE------QDWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQ 346

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1635 LYAKLRSTESDKREREKQLqdaeqemeemkekmrkfaKSKQQKILELEEENDRLRaeaqpvggtgESMEALLSSNSSLKE 1714
Cdd:TIGR04523  347 LKKELTNSESENSEKQREL------------------EEKQNEIEKLKKENQSYK----------QEIKNLESQINDLES 398

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1715 ELEKITLEHKTLSKEFEALMAEKDALSEETRNLKLQVEAQvlKQASLEATEKSDEPKDVIEEVTQAVVGKSQERDALSDS 1794
Cdd:TIGR04523  399 KIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKN--NSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRS 476

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1795 AKLEDSEailmgdgAKPGVSETFSSHDDIKNYLQQLDQLKGRIAELEMEKQKDRELSQALENEKNALLTQISAKDSELKL 1874
Cdd:TIGR04523  477 INKIKQN-------LEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNK 549

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1875 LEEEVTKrTTLNQQIQEELCRVTKLKETAEEEKDDLEER-------------LMNQLAELNGSIGNYYQDVTDAQIKNEQ 1941
Cdd:TIGR04523  550 DDFELKK-ENLEKEIDEKNKEIEELKQTQKSLKKKQEEKqelidqkekekkdLIKEIEEKEKKISSLEKELEKAKKENEK 628

                          650       660
                   ....*....|....*....|....*
gi 1039751015 1942 LESEMRNLQRCVSELEEEKQQLVKE 1966
Cdd:TIGR04523  629 LSSIIKNIKSKKNKLKQEVKQIKET 653
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1452-1656 3.34e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 52.46  E-value: 3.34e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1452 ELKKKPTELEEETNAKQQLQRKLQAALISRKEALKENKSLQEQLSSARDAVERLTKSLADVESQVSVQNQEKDAVLGKLT 1531
Cdd:COG4942     21 AAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELE 100

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1532 ILQEERDKLIAEMDR--------FLLENQSLSGSCESLKLaLGGLTEDKEKLMEELEsvrsskmAESTEWQEKHKELQKE 1603
Cdd:COG4942    101 AQKEELAELLRALYRlgrqpplaLLLSPEDFLDAVRRLQY-LKYLAPARREQAEELR-------ADLAELAALRAELEAE 172

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1039751015 1604 YEVLLQSYENVSNEAERIqhvvESVRQEKQELYAKLRSTESDKREREKQLQDA 1656
Cdd:COG4942    173 RAELEALLAELEEERAAL----EALKAERQKLLARLEKELAELAAELAELQQE 221
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 683-1119 3.39e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 53.02  E-value: 3.39e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  683 HQGELERLKTQVLELETSLHTAEETYKRNLSEKVKEISSLTQLSEEVKESAEEARSTLAAVTEERDQLLYQVKELDVLAE 762
Cdd:COG1196    335 LEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLE 414

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  763 LRARVQELESSLAEAEKQRGLDYESQRAQHNLLTEQIHSLSIEAKSKDVKIEALQRELDGVQLQFCEQGTQMKTLQSQLE 842
Cdd:COG1196    415 RLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLL 494

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  843 AKE-----REVREGTERLRDISQEMEGLSQALS---------QKELEIAKMDQLLLEKQKDVETLQQTIQE-KDQQVTEL 907
Cdd:COG1196    495 LLLeaeadYEGFLEGVKAALLLAGLRGLAGAVAvligveaayEAALEAALAAALQNIVVEDDEVAAAAIEYlKAAKAGRA 574

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  908 SFSMTEKM--VQLNEEKFSLGV---------------EIKTLKEQLNLLSRTEEATK-------------EQVEESGAGS 957
Cdd:COG1196    575 TFLPLDKIraRAALAAALARGAigaavdlvasdlreaDARYYVLGDTLLGRTLVAARleaalrravtlagRLREVTLEGE 654

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  958 SLKLGHDESGQEGLQQELELLRKESEQRKRKLQAALINRKELLQKVSQLEEELAKVREDSRKEIPFGENERRKLEEDREN 1037
Cdd:COG1196    655 GGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAER 734

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1038 RDDPEEW-----GTSKWREVEASLKQTISEKEVELEGIRRDLKEK----TAAEEELQAVVQRmtrdLQSKTKQIDLLQEE 1108
Cdd:COG1196    735 EELLEELleeeeLLEEEALEELPEPPDLEELERELERLEREIEALgpvnLLAIEEYEELEER----YDFLSEQREDLEEA 810

                          490
                   ....*....|.
gi 1039751015 1109 VTENQATIQKL 1119
Cdd:COG1196    811 RETLEEAIEEI 821
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
717-952 3.56e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 53.00  E-value: 3.56e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  717 KEISSLTQL-------SEEVKESAEEARSTLAAVTEERDQLLYQVKELDVLAELRARVQELESSLAEAEKQRGLD----- 784
Cdd:COG4913    204 KPIGDLDDFvreymleEPDTFEAADALVEHFDDLERAHEALEDAREQIELLEPIRELAERYAAARERLAELEYLRaalrl 283

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  785 YESQRAQHNL------LTEQIHSLSIEAKSKDVKIEALQRELDGVQLQFCEQGTQmktlqsQLEAKEREVREGTERLRDI 858
Cdd:COG4913    284 WFAQRRLELLeaeleeLRAELARLEAELERLEARLDALREELDELEAQIRGNGGD------RLEQLEREIERLERELEER 357

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  859 SQEMEGLSQALSQKELEIAKMDQLLLEKQKDVETLQQTIQEKDQQVTELSFSMTEKMVQLNEEKFSLGVEIKTLKEQLNL 938
Cdd:COG4913    358 ERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSN 437

                          250
                   ....*....|....
gi 1039751015  939 LSRTEEATKEQVEE 952
Cdd:COG4913    438 IPARLLALRDALAE 451
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
2098-2569 3.86e-06

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 52.73  E-value: 3.86e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2098 ESIKSQIKQKDE-DLLRRLEQaeekHRKEKKNMQEKLDALHREKAHVEETLAEIQVSLTRKDQEMKELQgSLDSTLAQLA 2176
Cdd:PRK02224   190 DQLKAQIEEKEEkDLHERLNG----LESELAELDEEIERYEEQREQARETRDEADEVLEEHEERREELE-TLEAEIEDLR 264

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2177 AFTKSMSSLQDDRDRVIDEAKKWERRFGDAIQTKEEEVRLKEENCIALKDQLRQMAIHMEELKIT-----VSRLEHDKEI 2251
Cdd:PRK02224   265 ETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRleecrVAAQAHNEEA 344

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2252 wESKAQTELQHHQKAyDKLQEENKELTSQLEDARQLYHDSKNELTKLESELKSLK----DQTTDLNNS---LEKCKEHEN 2324
Cdd:PRK02224   345 -ESLREDADDLEERA-EELREEAAELESELEEAREAVEDRREEIEELEEEIEELRerfgDAPVDLGNAedfLEELREERD 422

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2325 NLEGIIKQQEADIQNCKFSCEQLETDLAASR-------------------------ELTSRLHD---EINAKEQKIISLL 2376
Cdd:PRK02224   423 ELREREAELEATLRTARERVEEAEALLEAGKcpecgqpvegsphvetieedrerveELEAELEDleeEVEEVEERLERAE 502

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2377 SGKEEAIQL--------AVEELHQQHSKEIKE----LENLLSQEEEENVALEEENKRALEKTNQLTEALEAIkKESFEQK 2444
Cdd:PRK02224   503 DLVEAEDRIerleerreDLEELIAERRETIEEkrerAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEV-AELNSKL 581

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2445 AQLDSFVKSMSSLQDDRDRIVSDYRQLEERH--LSAILEKDQLIQDAAAEnnkLKEEMRGLRSHMDDLNSENAKLD-AEL 2521
Cdd:PRK02224   582 AELKERIESLERIRTLLAAIADAEDEIERLRekREALAELNDERRERLAE---KRERKRELEAEFDEARIEEAREDkERA 658

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1039751015 2522 VQYRRDLNEVIAIKDSQQKQLLDA------QLQQNKELRNECTKLEERLKGLEA 2569
Cdd:PRK02224   659 EEYLEQVEEKLDELREERDDLQAEigavenELEELEELRERREALENRVEALEA 712
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1816-2032 4.04e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 52.07  E-value: 4.04e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1816 TFSSHDDIKNYLQQLDQLKGRIAELEMEKQKDRELSQALENEKNALLTQISAKDSELKLLEEEVtkrttlnQQIQEELCR 1895
Cdd:COG4942     15 AAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQEL-------AALEAELAE 87

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1896 VTKLKETAEEEKDDLEERLMNQLAELNGSIGNYY-------QDVTDAQIK-------NEQLESEMRNLQRCVSELEEEKQ 1961
Cdd:COG4942     88 LEKEIAELRAELEAQKEELAELLRALYRLGRQPPlalllspEDFLDAVRRlqylkylAPARREQAEELRADLAELAALRA 167

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1039751015 1962 QLVKEKTKVESEIRKEYMEKIQGAQKGPANKSHAKELQELLREKQQEVKQLQKDCIRYLERISALEKTVKA 2032
Cdd:COG4942    168 ELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAA 238
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 123-373 6.53e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 51.30  E-value: 6.53e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  123 AALPPEAQAEELSKHNKSSTEEEMEIEKIKHELQEKEKLISSLQAQLDQSEQasQLDKSSAEMEDfvlMKQQLQEKEELI 202
Cdd:COG4942     11 LALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALER--RIAALARRIRA---LEQELAALEAEL 85

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  203 STLQTQLSQTQAEQAAQLSSMQQVVRekdarfeTQVRLHEDELLQLVTQSDVETEMQQKLRVMQRKLEEHEEallgRAQV 282
Cdd:COG4942     86 AELEKEIAELRAELEAQKEELAELLR-------ALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARRE----QAEE 154

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  283 VDLLQKELTSAEQRNQVLSQQLQLLEAEHNTLKNTMETERQESKTLMEKVELEVAERKLSFHNLQEEMHQLQGQLERAGQ 362
Cdd:COG4942    155 LRADLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEA 234

                          250
                   ....*....|.
gi 1039751015  363 AQADLETQYSA 373
Cdd:COG4942    235 EAAAAAERTPA 245
PTZ00121 PTZ00121
MAEBL; Provisional
 714-1229 6.73e-06

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 52.45  E-value: 6.73e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  714 EKVKEISSLTQLSEEVKESAEEARSTLAAVTEERDQLLYQVKELDVLAELRARVQELEsslaEAEKQRGLDyESQRAQHN 793
Cdd:PTZ00121  1227 EAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELK----KAEEKKKAD-EAKKAEEK 1301

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  794 LLTEQIHSLSIEAKSKD---VKIEALQRELDGVQLQFCEQGTQMKTLQSQLEAKEREVREGTERlrdisQEMEGLSQALS 870
Cdd:PTZ00121  1302 KKADEAKKKAEEAKKADeakKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEK-----AEAAEKKKEEA 1376

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  871 QKELEIAKMDQlllEKQKDVETLQQTIQEKDQQVTELSFSMTEKmvQLNEEKFSLGVEIKT---LKEQLNLLSRTEEATK 947
Cdd:PTZ00121  1377 KKKADAAKKKA---EEKKKADEAKKKAEEDKKKADELKKAAAAK--KKADEAKKKAEEKKKadeAKKKAEEAKKADEAKK 1451

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  948 EQVEESGAGSSLKLGHDESGQEGLQQELELLRKESEQRKRKLQAalinrKELLQKVSQLEEELAKVREDSRKEIPFGENE 1027
Cdd:PTZ00121  1452 KAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEA-----KKKADEAKKAAEAKKKADEAKKAEEAKKADE 1526

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1028 RRKLEEDRENRDDPEEWGTSKWREVEASlkqtiseKEVELEGIRRDLKEKTAAEEELQAVVQRMTRDLQSKTKQIDLLQE 1107
Cdd:PTZ00121  1527 AKKAEEAKKADEAKKAEEKKKADELKKA-------EELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMK 1599

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1108 EVTENQatiqklvtgTMDAGNGGSAAPVKETAASSPPGAggEEHWKPELEGRILDLEKDKTQLQKKLQEALIARKAILKK 1187
Cdd:PTZ00121  1600 LYEEEK---------KMKAEEAKKAEEAKIKAEELKKAE--EEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAK 1668

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|..
gi 1039751015 1188 AQEKEKQLKEELREQKDAYHHLQGQFHEQNKEKENiADQLRQ 1229
Cdd:PTZ00121  1669 KAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKK-AEELKK 1709
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2110-2318 7.37e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 51.30  E-value: 7.37e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2110 DLLRRLEQAEEKHRKEKKNMQEKLDALHREKAHVEETLAEIQVSLTRKDQEMKELQGSLDSTLAQLAAFTKSMSSLQDDR 2189
Cdd:COG4942     20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAEL 99

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2190 D-------RVIDEAKKWERRFGDAIQTKEEEVRLKEENCIALKDQLRQMAIHMEELKITVSRLEHDKEiwesKAQTELQH 2262
Cdd:COG4942    100 EaqkeelaELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRA----ELEAERAE 175

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1039751015 2263 HQKAYDKLQEENKELTSQLEDARQLYHDSKNELTKLESELKSLKDQTTDLNNSLEK 2318
Cdd:COG4942    176 LEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIAR 231
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
683-1119 9.07e-06

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 51.60  E-value: 9.07e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  683 HQGELERLKTQVLELETSLHTAEETYK---RNLSEKVKEISSLTQLSEEVKESAEEAR--STLAAVTEERDQLLYQVKEL 757
Cdd:PRK03918   236 LKEEIEELEKELESLEGSKRKLEEKIReleERIEELKKEIEELEEKVKELKELKEKAEeyIKLSEFYEEYLDELREIEKR 315

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  758 -----DVLAELRARVQELESSLAEAEKQRGLDYESQRAQHNLltEQIHSLSIEAKSKDVKIEALQRELDGVQLQFCEQgt 832
Cdd:PRK03918   316 lsrleEEINGIEERIKELEEKEERLEELKKKLKELEKRLEEL--EERHELYEEAKAKKEELERLKKRLTGLTPEKLEK-- 391

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  833 QMKTLQSQLEAKEREVREGTERLRDISQEMEGLSQALSQ------------KELEIAKMDQLLLEKQKDVETLQQTIQEK 900
Cdd:PRK03918   392 ELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEElkkakgkcpvcgRELTEEHRKELLEEYTAELKRIEKELKEI 471

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  901 DQQVTELSFSMTEKMVQLNEEK-----FSLGVEIKTLKEQLNLLSRTEEATKEQVEESGAGSSLKLGHDESGQEGLQQEL 975
Cdd:PRK03918   472 EEKERKLRKELRELEKVLKKESeliklKELAEQLKELEEKLKKYNLEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKL 551

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  976 ELLRKESEQRKRKLQAALINRKELLQK--------VSQLEEELAKVREDSRKEIPFGENERRKleEDRENRDDPEEWGTS 1047
Cdd:PRK03918   552 EELKKKLAELEKKLDELEEELAELLKEleelgfesVEELEERLKELEPFYNEYLELKDAEKEL--EREEKELKKLEEELD 629

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1039751015 1048 KWREVEASLKQTISEKEVELEGIRRDLKEKTaaEEELQAVVQRMTRDLQSKTKQIDLLQEEVTENQATIQKL 1119
Cdd:PRK03918   630 KAFEELAETEKRLEELRKELEELEKKYSEEE--YEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKL 699
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1493-2039 1.04e-05

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 51.58  E-value: 1.04e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1493 EQLSSARDAVERLTK----SLADVESQVSvQNQEKDAVlGKLTILQEERDKLIAEMDRFLLENQSLSGSCESLKLALGGL 1568
Cdd:PRK02224   169 ERASDARLGVERVLSdqrgSLDQLKAQIE-EKEEKDLH-ERLNGLESELAELDEEIERYEEQREQARETRDEADEVLEEH 246

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1569 TEDKEKL------MEELESVRSSKMAESTEWQEKHKELQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQELYAKLRST 1642
Cdd:PRK02224   247 EERREELetleaeIEDLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEEL 326

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1643 ESDKREREKQLQDAEQEmeemkekmrkfAKSKQQKILELEEENDRLRAEAQPVGGTGESMEALLSSNSSLKEELEKitlE 1722
Cdd:PRK02224   327 RDRLEECRVAAQAHNEE-----------AESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEE---E 392

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1723 HKTLSKEFEALMAEKDALSEETRNLKLQVEAQVLKQASLEATEKSDEpkDVIEEVTQAV-----------VGKSQERDAL 1791
Cdd:PRK02224   393 IEELRERFGDAPVDLGNAEDFLEELREERDELREREAELEATLRTAR--ERVEEAEALLeagkcpecgqpVEGSPHVETI 470

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1792 SDS-AKLEDSEAILmgdgakpgvSETFSSHDDIKNYLQQLDQLKGRIAELEMEKQKdRELSQALENEKNALLTQISAKDS 1870
Cdd:PRK02224   471 EEDrERVEELEAEL---------EDLEEEVEEVEERLERAEDLVEAEDRIERLEER-REDLEELIAERRETIEEKRERAE 540

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1871 EL-----KLLEEEVTKR---TTLNQQIQEELCRVTKLKETAEEEKDDLEErlMNQLAELNGSIGNYYQDVTDAQIKNEQL 1942
Cdd:PRK02224   541 ELreraaELEAEAEEKReaaAEAEEEAEEAREEVAELNSKLAELKERIES--LERIRTLLAAIADAEDEIERLREKREAL 618

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1943 esemrnlqrcvSELEEEKQQLVKEKTKVESEIRKEYME-KIQGAQKGPAN-KSHAKELQELLREKQQEVKQLQKDC---- 2016
Cdd:PRK02224   619 -----------AELNDERRERLAEKRERKRELEAEFDEaRIEEAREDKERaEEYLEQVEEKLDELREERDDLQAEIgave 687

                          570       580
                   ....*....|....*....|....*....
gi 1039751015 2017 --IRYLE----RISALEKTVKALEFVHTE 2039
Cdd:PRK02224   688 neLEELEelreRREALENRVEALEALYDE 716
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1317-2059 1.21e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 51.22  E-value: 1.21e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1317 IASELAKKSEEVLLLQDQINEQGLEIQNLKAASVEAQAHTELLKQELESSQlkvaglEHLKTLQPELDALHKHMGQKEEE 1396
Cdd:TIGR02169  292 VKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELE------REIEEERKRRDKLTEEYAELKEE 365

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1397 VNYLYGQLSEKEQTLTTVQTEMveqerliKALHTQLEMQAKEHEERLKQAQVEICELKKKPTELEEETNAKQQLQRKLqA 1476
Cdd:TIGR02169  366 LEDLRAELEEVDKEFAETRDEL-------KDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKI-N 437

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1477 ALISRKEALKEN--------KSLQEQLSSARDAVERLTKSLADVESQVSVQNQEKDAVLGKLTILQEERDKLIAEMDRFL 1548
Cdd:TIGR02169  438 ELEEEKEDKALEikkqewklEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLK 517

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1549 LENQSLSGSCESL-----------KLALGG-----LTEDKEKLMEELESVRSSKMAEST-----EWQEKHKELQKEYEVL 1607
Cdd:TIGR02169  518 ASIQGVHGTVAQLgsvgeryataiEVAAGNrlnnvVVEDDAVAKEAIELLKRRKAGRATflplnKMRDERRDLSILSEDG 597

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1608 L-----------QSYENVSNEAERIQHVVESVrQEKQELYAKLRSTESDKREREKqlQDAEQEMEEMKEKMRKFAKSKQQ 1676
Cdd:TIGR02169  598 VigfavdlvefdPKYEPAFKYVFGDTLVVEDI-EAARRLMGKYRMVTLEGELFEK--SGAMTGGSRAPRGGILFSRSEPA 674

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1677 KILELEEENDRLRAEAQPVGGTGESMEALLSSNSSLKEELEKitlEHKTLSKEFEALMAEKDALSEETRNLKLQveaqvL 1756
Cdd:TIGR02169  675 ELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASR---KIGEIEKEIEQLEQEEEKLKERLEELEED-----L 746

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1757 KQASLEATEKSDEPKDVIEEVTQAVVGKSQERDALSDsakLEDSEAilmgdgakpgvsetfsshddiknyLQQLDQLKGR 1836
Cdd:TIGR02169  747 SSLEQEIENVKSELKELEARIEELEEDLHKLEEALND---LEARLS------------------------HSRIPEIQAE 799

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1837 IAELEMEKQKDRELSQALENEKNALltqisakDSELKLLEEEvtkrttlnqqIQEELCRVTKLKETAEEEKDDLEerlmn 1916
Cdd:TIGR02169  800 LSKLEEEVSRIEARLREIEQKLNRL-------TLEKEYLEKE----------IQELQEQRIDLKEQIKSIEKEIE----- 857

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1917 qlaELNGSIGNYYQDVTDAQIKNEQLESEMRNLQRCVSELEEEKQQLVKEKTKVESEIRKEYMEKIQGAQKGPANKSHAK 1996
Cdd:TIGR02169  858 ---NLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELS 934

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1039751015 1997 ELQELLREKQQEV------KQLQKDCIRYLERISALEKTVKALEFVHTESQKDLDVTKGNLAQAVEHRK 2059
Cdd:TIGR02169  935 EIEDPKGEDEEIPeeelslEDVQAELQRVEEEIRALEPVNMLAIQEYEEVLKRLDELKEKRAKLEEERK 1003
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
760-1032 1.23e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 51.45  E-value: 1.23e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  760 LAELRARVQELESSLAEAEKQRgldyESQRAQHNLLTEQIHSLS--IEAKSKDVKIEALQRELDGV--QLQFCEQG-TQM 834
Cdd:COG4913    612 LAALEAELAELEEELAEAEERL----EALEAELDALQERREALQrlAEYSWDEIDVASAEREIAELeaELERLDASsDDL 687

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  835 KTLQSQLEAKEREVREGTERLRDISQEMEGLSQALSQKELEIAKMDQLLLEKQKDVETLQQtiQEKDQQVTELSFSMTEK 914
Cdd:COG4913    688 AALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELR--ALLEERFAAALGDAVER 765

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  915 MVQLNeekfsLGVEIKTLKEQLNLLSRTEEATKEQVEESGAGSSLKLGHDESGQEGLQQELELLRKES----EQR-KRKL 989
Cdd:COG4913    766 ELREN-----LEERIDALRARLNRAEEELERAMRAFNREWPAETADLDADLESLPEYLALLDRLEEDGlpeyEERfKELL 840

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*....
gi 1039751015  990 QAALINRKELLQkvSQLEEELAKVRE------DSRKEIPFGENERRKLE 1032
Cdd:COG4913    841 NENSIEFVADLL--SKLRRAIREIKEridplnDSLKRIPFGPGRYLRLE 887
PTZ00121 PTZ00121
MAEBL; Provisional
 1728-2572 1.29e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 51.30  E-value: 1.29e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1728 KEFEALMAEKDALSEETRN-LKLQVEAQVLKQASLEATEKSDEPKDVIEEVTQAV-VGKSQERDALSDSAKLEDSEAILM 1805
Cdd:PTZ00121  1077 KDFDFDAKEDNRADEATEEaFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEeARKAEDARKAEEARKAEDAKRVEI 1156

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1806 GDGAKPGVSETFSSHDDiknylqqlDQLKGRIAELEMEKQKDRELSQALENEKnallTQISAKDSELKLLEEevtKRTTL 1885
Cdd:PTZ00121  1157 ARKAEDARKAEEARKAE--------DAKKAEAARKAEEVRKAEELRKAEDARK----AEAARKAEEERKAEE---ARKAE 1221

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1886 NQQIQEELCRVTKLKETAEEEKDDLEERLMNQLAELNGSIGNYYQDvTDAQIKNEQlesemrnlQRCVSELEEekqqlVK 1965
Cdd:PTZ00121  1222 DAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFAR-RQAAIKAEE--------ARKADELKK-----AE 1287

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1966 EKTKVESEIRKEYMEKIQGAQKGPANKSHAKELQELLREKQQEVKQLQKdciryleriSALEKTVKAlefvhtesqkdld 2045
Cdd:PTZ00121  1288 EKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKK---------KAEEAKKAA------------- 1345

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2046 vtkgNLAQAVEHRKKAQAELSSFKILLDDTQSEAARVLADNLKLKKELQSNKESIKSQIKQ--KDEDLLRRLEQAEEKHR 2123
Cdd:PTZ00121  1346 ----EAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEdkKKADELKKAAAAKKKAD 1421

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2124 KEKKNMQEKLDALHREKAHVEETLAEiqvSLTRKDQEMKELQGSLDSTlaqlaaftksmsslqdDRDRVIDEAKK--WER 2201
Cdd:PTZ00121  1422 EAKKKAEEKKKADEAKKKAEEAKKAD---EAKKKAEEAKKAEEAKKKA----------------EEAKKADEAKKkaEEA 1482

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2202 RFGDAIQTKEEEVRLKEENcialkdqlrqmAIHMEELKITVSRLEHDKEIWESKAQTELQHHQKAYDKLQEENKELTSQL 2281
Cdd:PTZ00121  1483 KKADEAKKKAEEAKKKADE-----------AKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADEL 1551

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2282 EDARQLyhDSKNELTKLESELKSLKDQTTDLNNSLEKCKEHENNLEGIIKQQEadiQNCKFSCEQLEtdlaasreltsrl 2361
Cdd:PTZ00121  1552 KKAEEL--KKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYE---EEKKMKAEEAK------------- 1613

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2362 hdeiNAKEQKIISLLSGKEEAIQLAVEELHQQHSKEIKELENLLSQEEEENVALEEENKRALEKTNQlteALEAIKKESF 2441
Cdd:PTZ00121  1614 ----KAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKK---AEEAKKAEED 1686

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2442 EQKAQldsfvksmsslqddrdriVSDYRQLEERHLSAILEKDQLIQDAAAENNKLKEEMRGLRSHMDDLNSENAKLDAEL 2521
Cdd:PTZ00121  1687 EKKAA------------------EALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEE 1748

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1039751015 2522 VQYRRDLNEVIAIKDSQQKQLLDAQLQQNKELRNECTKLEERLKGLEAEKQ 2572
Cdd:PTZ00121  1749 AKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKK 1799
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 2234-2753 1.34e-05

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 51.27  E-value: 1.34e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2234 HMEELKITVSRLEHD----KEIWESK----------AQTELQHHQKAYDKLQEENKELTSQLEDARQLYHDSKNELTKLE 2299
Cdd:pfam15921  318 QLSDLESTVSQLRSElreaKRMYEDKieelekqlvlANSELTEARTERDQFSQESGNLDDQLQKLLADLHKREKELSLEK 397

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2300 SELKSLKDQTTDLNNSLEKCKEHENNLEGIIKQQEADIQNCKFSCE-QLETDLAAsreltsrlhdeinakeqkiislLSG 2378
Cdd:pfam15921  398 EQNKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSECQgQMERQMAA----------------------IQG 455

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2379 KEEAIQlAVEELHQQHSKEIKELENLLSQEEEENVALEEENKRALEKTNQLTE---ALEAIKKESFEQKAQLDSFVKSMS 2455
Cdd:pfam15921  456 KNESLE-KVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEkerAIEATNAEITKLRSRVDLKLQELQ 534

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2456 SLQDDRDRIVSDYRQLEERHLSaILEKDQLIQDAAAENNKLKEEMRGLRSHMDDLNSENAKLDAELVQYRRDLNEVIAIK 2535
Cdd:pfam15921  535 HLKNEGDHLRNVQTECEALKLQ-MAEKDKVIEILRQQIENMTQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQEFKILK 613

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2536 DSQQKQLldaqlqqnKELRNECTKLE-ERLKGLEAEKQSLQMSSDaLQKEKQGLSKEIKNLQTQLTALQE---------- 2604
Cdd:pfam15921  614 DKKDAKI--------RELEARVSDLElEKVKLVNAGSERLRAVKD-IKQERDQLLNEVKTSRNELNSLSEdyevlkrnfr 684

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2605 ------EGTLGVYHAQLKAKEEELQRLNMALSSSQKRTADLEEELVCVQKEATRKVSEIeDQLKKELKHLHHDAGIMRNE 2678
Cdd:pfam15921  685 nkseemETTTNKLKMQLKSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQI-DALQSKIQFLEEAMTNANKE 763

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1039751015 2679 TETAEERVAELARDLVEMEQKLLTVTKENKDLMAQIQAFGRSMSSLQDSRDHATEELGDLKKKYDASLKELAQLK 2753
Cdd:pfam15921  764 KHFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANMEVALDKASLQFAECQDIIQRQEQESVRLK 838
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 2254-2909 1.38e-05

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 51.17  E-value: 1.38e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2254 SKAQTELQHHQKAYDKLQEENKELTSQLEDARQLYHDSKNELTKLESELKSLKDQTTDLNNSLEKCKEHENNLEGIIKQQ 2333
Cdd:TIGR04523   29 NKQDTEEKQLEKKLKTIKNELKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDLSKI 108

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2334 EADIQNCKfsceqletdlaasreltsrlhDEINAKEQKIISLLSGKEEaiqlaVEELHQQHSKEIKELENLLsqeeeenv 2413
Cdd:TIGR04523  109 NSEIKNDK---------------------EQKNKLEVELNKLEKQKKE-----NKKNIDKFLTEIKKKEKEL-------- 154

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2414 aleeenkralektNQLTEALEAIKKESFEQKAQLDSFVKSMSSLQDDRDRIVSDYRQLEERhLSAILEKDQLIQDAAAEN 2493
Cdd:TIGR04523  155 -------------EKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKLELL-LSNLKKKIQKNKSLESQI 220

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2494 NKLKEEMRGLRSHMDDLNSENAKLDAELVQYRRDLNEVIAIKDSQQKQLLDAQlqqnkelrNECTKLEERLKGLEAEKQS 2573
Cdd:TIGR04523  221 SELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQ--------KELEQNNKKIKELEKQLNQ 292

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2574 LQMSSDALQKEKQ-----GLSKEIKNLQTQLTALQeegtlgvyhAQLKAKEEELQRLNMALSSSQKRTADLEEELVCVQK 2648
Cdd:TIGR04523  293 LKSEISDLNNQKEqdwnkELKSELKNQEKKLEEIQ---------NQISQNNKIISQLNEQISQLKKELTNSESENSEKQR 363

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2649 EATRKVSEIE------DQLKKELKHLHHDAGIMRNETETAEE---------RVAELARDLVEMEQKLLTVT-----KENK 2708
Cdd:TIGR04523  364 ELEEKQNEIEklkkenQSYKQEIKNLESQINDLESKIQNQEKlnqqkdeqiKKLQQEKELLEKEIERLKETiiknnSEIK 443

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2709 DLMAQIQAFGRSMSSLQDSRDHATEELGDLKKKYDASLKELAQLKewQDSSREGDVLSQAAFPLSTSENVLSRLEKLNQQ 2788
Cdd:TIGR04523  444 DLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQ--KELKSKEKELKKLNEEKKELEEKVKDLTKKISS 521

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2789 LTSKDEQLLHLSSELESSHNQVQSISKAMTS------LQNERDRLWSELEKFR---KSEEGKQRAAAPSAASSPAEVQSL 2859
Cdd:TIGR04523  522 LKEKIEKLESEKKEKESKISDLEDELNKDDFelkkenLEKEIDEKNKEIEELKqtqKSLKKKQEEKQELIDQKEKEKKDL 601

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2860 KKAMSSLQNDRDRLLKELKNLQQQYLQMSQEMTELRPLKAQLQESQDQTK 2909
Cdd:TIGR04523  602 IKEIEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIK 651
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2776-3054 1.68e-05

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 50.71  E-value: 1.68e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2776 ENVLSRLEKLNQQLTSKDEQLLHLSSELESSHNQVQSISKAMTSLQNERDRLWSELEKFRKSEEGKQRaaapsaasspaE 2855
Cdd:COG1196    235 RELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQ-----------D 303

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2856 VQSLKKAMSSLQNDRDRLLKELKNLQQQYLQMSQEMTELRPLKAQLQESQDQTKALQVMEEELRQENLSWQHELRQLRME 2935
Cdd:COG1196    304 IARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEE 383

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2936 KNSWELHERRMKEQFLMAISDKDQQLGHLQSLLRELRSSSQAQILSTQYQRQASPETSASLDGSQKLVYETELLRTQLND 3015
Cdd:COG1196    384 LAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLE 463

                          250       260       270
                   ....*....|....*....|....*....|....*....
gi 1039751015 3016 SLKEIHQKELRIQQLNSKFSQLLEEKNVLSTQLSDASQS 3054
Cdd:COG1196    464 LLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEAD 502
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 1572-3075 1.80e-05

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 50.82  E-value: 1.80e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1572 KEKLMEELESVRSSKMAESTEWQEKHKELQKEYEV-------LLQSYENVSNEAERIQHVVESVRQEKQELYAKLRSTeS 1644
Cdd:TIGR01612  535 KAKLYKEIEAGLKESYELAKNWKKLIHEIKKELEEenedsihLEKEIKDLFDKYLEIDDEIIYINKLKLELKEKIKNI-S 613

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1645 DKREREKQLQDAEQEMEEMKEKMRKFAKSKQQKILELEEENDRL----RAEAQPVggTGESMEALLSSNSSLKEELEKIT 1720
Cdd:TIGR01612  614 DKNEYIKKAIDLKKIIENNNAYIDELAKISPYQVPEHLKNKDKIystiKSELSKI--YEDDIDALYNELSSIVKENAIDN 691

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1721 LEHKTlskEFEALMAEKDALSEETRNLklqvEAQVLKQASLEATEKSDEPKDVIEEVTQAVVGK-SQERDALsdsakLED 1799
Cdd:TIGR01612  692 TEDKA---KLDDLKSKIDKEYDKIQNM----ETATVELHLSNIENKKNELLDIIVEIKKHIHGEiNKDLNKI-----LED 759

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1800 seailmgdgAKPGVSETFSSHDDIKNYLQQLDQLKGRIAELE--------MEKQKDRELSQALENEKNALLTqISAKD-- 1869
Cdd:TIGR01612  760 ---------FKNKEKELSNKINDYAKEKDELNKYKSKISEIKnhyndqinIDNIKDEDAKQNYDKSKEYIKT-ISIKEde 829

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1870 -----SELKLLEEE----VTKRTTLNQQIQEELCR--------VTKLKETAEEEKDDLEERLMNQ----LAELNGSIGNY 1928
Cdd:TIGR01612  830 ifkiiNEMKFMKDDflnkVDKFINFENNCKEKIDSeheqfaelTNKIKAEISDDKLNDYEKKFNDskslINEINKSIEEE 909

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1929 YQDVTDAQIKNEQLE---------SEMRNLQRCVSELEEEKQQLVKEKTKVESEIRKEY----------MEKIQGAQKGP 1989
Cdd:TIGR01612  910 YQNINTLKKVDEYIKicentkesiEKFHNKQNILKEILNKNIDTIKESNLIEKSYKDKFdntlidkineLDKAFKDASLN 989

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1990 ANKSHAKELQELLREKQ------------QEVKQLQKDCIRYLERISALEKTVKALEFV-HTESQKDLDVTKGNLAQAVE 2056
Cdd:TIGR01612  990 DYEAKNNELIKYFNDLKanlgknkenmlyHQFDEKEKATNDIEQKIEDANKNIPNIEIAiHTSIYNIIDEIEKEIGKNIE 1069

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2057 HR-----KKAQAELSSFKIL--------LDDTQSEaarvlaDNLKLKKELQSNKESIKSQIKQKDEDL--LRRLEQAEEK 2121
Cdd:TIGR01612 1070 LLnkeilEEAEINITNFNEIkeklkhynFDDFGKE------ENIKYADEINKIKDDIKNLDQKIDHHIkaLEEIKKKSEN 1143

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2122 HRKEKKNMQEKLDALHREKAH---VEETLAEIQVSLTRKDQEmKELQGSLDSTLAQLAAFTKSMSSLQDDRD-------- 2190
Cdd:TIGR01612 1144 YIDEIKAQINDLEDVADKAISnddPEEIEKKIENIVTKIDKK-KNIYDEIKKLLNEIAEIEKDKTSLEEVKGinlsygkn 1222

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2191 ------RVIDEAKKWERRFGDAIQTKEEEV-RLKEENCIALKDQLRQMAIHMEelkITVSRLEHDKEiweSKAQTELQHH 2263
Cdd:TIGR01612 1223 lgklflEKIDEEKKKSEHMIKAMEAYIEDLdEIKEKSPEIENEMGIEMDIKAE---METFNISHDDD---KDHHIISKKH 1296

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2264 QKAYDKLQEENKELT------SQLEDARQLYHDSKNELTKLESELKSLKDQTTDLNNSLEKckeheNNLEGIIKQQEADI 2337
Cdd:TIGR01612 1297 DENISDIREKSLKIIedfseeSDINDIKKELQKNLLDAQKHNSDINLYLNEIANIYNILKL-----NKIKKIIDEVKEYT 1371

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2338 QNCKFSCEQLETDLAASRELTSRLHDEINAKE--QKIISLLSGKE--EAIQ---------LAVEELHQQHSKEIKEL-EN 2403
Cdd:TIGR01612 1372 KEIEENNKNIKDELDKSEKLIKKIKDDINLEEckSKIESTLDDKDidECIKkikelknhiLSEESNIDTYFKNADENnEN 1451

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2404 LL------------SQEEEENVALEEEN---------KRALEKTNQLTEALEAIKKESFEQKAQLDSFVKSMSSL----- 2457
Cdd:TIGR01612 1452 VLllfkniemadnkSQHILKIKKDNATNdhdfninelKEHIDKSKGCKDEADKNAKAIEKNKELFEQYKKDVTELlnkys 1531

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2458 -----------QDDRDRIVSDYRQLE----------ERHLSAILEKDQLIQDAAAENNKLKEEMRGLRSHMDDLNSENAK 2516
Cdd:TIGR01612 1532 alaiknkfaktKKDSEIIIKEIKDAHkkfileaeksEQKIKEIKKEKFRIEDDAAKNDKSNKAAIDIQLSLENFENKFLK 1611

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2517 LDaelvQYRRDLNEVIAIKDSQQKQL----LDAQLQQNKELRNECTKLEERLKGLEAEKQSLQMSsdalQKEKQGLSKEI 2592
Cdd:TIGR01612 1612 IS----DIKKKINDCLKETESIEKKIssfsIDSQDTELKENGDNLNSLQEFLESLKDQKKNIEDK----KKELDELDSEI 1683

                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2593 KNLQTQLTALQEEGTLGVYHA---QLKAKEEELQRLNMALSSSQKR------TADLEeelvcvQKEATRKVSEIEDQLKK 2663
Cdd:TIGR01612 1684 EKIEIDVDQHKKNYEIGIIEKikeIAIANKEEIESIKELIEPTIENlissfnTNDLE------GIDPNEKLEEYNTEIGD 1757

                         1290      1300      1310      1320      1330      1340      1350      1360
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2664 ELKHLHHDAGIMRNETET-AEERVA--ELARDLVEMEQKLLTVTKENKDLMA-----QIQAFGRSMSSLQDSRDHA---- 2731
Cdd:TIGR01612 1758 IYEEFIELYNIIAGCLETvSKEPITydEIKNTRINAQNEFLKIIEIEKKSKSylddiEAKEFDRIINHFKKKLDHVndkf 1837

                         1370      1380      1390      1400      1410      1420      1430      1440
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2732 TEELGDLKKKYDASLKELAQLKEWQDSSREGDVLSQaafplsTSENVLSRLEKLNQQLTSKDEQLLHLSSELESSHN-QV 2810
Cdd:TIGR01612 1838 TKEYSKINEGFDDISKSIENVKNSTDENLLFDILNK------TKDAYAGIIGKKYYSYKDEAEKIFINISKLANSINiQI 1911

                         1450      1460      1470      1480      1490      1500      1510      1520
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2811 QSiSKAMTSLQNERDRLWSELE-------KFRKSEEGKQRAAAPSAASSPAEVQSLKKAMSSLQNDRDRLLKELKNlQQQ 2883
Cdd:TIGR01612 1912 QN-NSGIDLFDNINIAILSSLDsekedtlKFIPSPEKEPEIYTKIRDSYDTLLDIFKKSQDLHKKEQDTLNIIFEN-QQL 1989

                         1530      1540      1550      1560      1570      1580      1590      1600
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2884 Y--LQMSQEMTE-LRPLKAQLQESQDQTKALQVMEEELRQENLSWQH--------ELRQLRMEKNSWELHERRMKEQFLM 2952
Cdd:TIGR01612 1990 YekIQASNELKDtLSDLKYKKEKILNDVKLLLHKFDELNKLSCDSQNydtilelsKQDKIKEKIDNYEKEKEKFGIDFDV 2069

                         1610      1620      1630      1640      1650      1660      1670      1680
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2953 AISDKdqqlgHLQSLLRELRSSSQAQILSTQYQRQASPETSASLDGSQKLVYETELLRTqlndslkEIHQKELRIQQLNS 3032
Cdd:TIGR01612 2070 KAMEE-----KFDNDIKDIEKFENNYKHSEKDNHDFSEEKDNIIQSKKKLKELTEAFNT-------EIKIIEDKIIEKND 2137

                         1690      1700      1710      1720
                   ....*....|....*....|....*....|....*....|....
gi 1039751015 3033 KFSQLLE-EKNVLSTQLSDASQSLRENQHHYSNLFNHCAILEKE 3075
Cdd:TIGR01612 2138 LIDKLIEmRKECLLFSYATLVETLKSKVINHSEFITSAAKFSKD 2181
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
2255-2884 1.83e-05

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 50.83  E-value: 1.83e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2255 KAQTELQHHQKAYDKLQEENKELTSQLEDARQLYHDSKNELTKLESELKSLKDQTTDLNNSLEKCKEHENNLE---GIIK 2331
Cdd:PRK03918   162 NAYKNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEelkEEIE 241

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2332 QQEADIQNCKFSCEQLETDLAASRELTSRLHDEINAKEQKIISLLSGKEEAIQ-LAVEELHQQHSKEIKELENLLSQEEE 2410
Cdd:PRK03918   242 ELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKEKAEEyIKLSEFYEEYLDELREIEKRLSRLEE 321

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2411 ENVALeeenKRALEKTNQLTEALEAIKKESFEQKAQLDSFVKSMSSLQDDRdRIVSDYRQLEERhlsailEKDQLIQDAA 2490
Cdd:PRK03918   322 EINGI----EERIKELEEKEERLEELKKKLKELEKRLEELEERHELYEEAK-AKKEELERLKKR------LTGLTPEKLE 390

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2491 AENNKLKEEMRGLRSHMDDLNSENAKLDAELVQYRRDLNEVIAIK-----------DSQQKQLLDAQLQQNKELRNECTK 2559
Cdd:PRK03918   391 KELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKgkcpvcgreltEEHRKELLEEYTAELKRIEKELKE 470

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2560 LEERLKGLEAEKQSLQMssdALQKEKQGLSkeIKNLQTQLTALQEEgtLGVYHAQ-LKAKEEELQRLNMALSSSQKRTAD 2638
Cdd:PRK03918   471 IEEKERKLRKELRELEK---VLKKESELIK--LKELAEQLKELEEK--LKKYNLEeLEKKAEEYEKLKEKLIKLKGEIKS 543

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2639 LEEELVCVQ--KEATRKVSEIEDQLKKELKHLHHdagIMRNETETAEERVAELARDLVEMEQKLLTVtkenKDLMAQIQA 2716
Cdd:PRK03918   544 LKKELEKLEelKKKLAELEKKLDELEEELAELLK---ELEELGFESVEELEERLKELEPFYNEYLEL----KDAEKELER 616

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2717 FGRSMSSLQDSRDHATEELGDLKKKYDASLKELAQLKEWQDSSRegdvlsqaafplstsenvlsrLEKLNQQLTSKDEQL 2796
Cdd:PRK03918   617 EEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEEE---------------------YEELREEYLELSREL 675

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2797 LHLSSELESSHNQVQSISKAMTSLQNERDrlwsELEKFRKseegkqraaapsaasspaEVQSLKKAMSSLQNDRDRlLKE 2876
Cdd:PRK03918   676 AGLRAELEELEKRREEIKKTLEKLKEELE----EREKAKK------------------ELEKLEKALERVEELREK-VKK 732


                   ....*...
gi 1039751015 2877 LKNLQQQY 2884
Cdd:PRK03918   733 YKALLKER 740
46 PHA02562
endonuclease subunit; Provisional
 1823-1981 1.88e-05

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 50.40  E-value: 1.88e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1823 IKNYLQQLDQLKGRIAELEMEKQKDRELSQALENEKNALLTQISAKDSELKLLEEEVTKRTTLnQQIQEELCRVTKLKE- 1901
Cdd:PHA02562   229 AKTIKAEIEELTDELLNLVMDIEDPSAALNKLNTAAAKIKSKIEQFQKVIKMYEKGGVCPTCT-QQISEGPDRITKIKDk 307

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1902 --------TAEEEKDDLEERLMNQLA-------ELNGSIGNYYQDVTDAQIKNEQLESEMRNLQRCVSELEEEKQQLVKE 1966
Cdd:PHA02562   308 lkelqhslEKLDTAIDELEEIMDEFNeqskkllELKNKISTNKQSLITLVDKAKKVKAAIEELQAEFVDNAEELAKLQDE 387

                          170
                   ....*....|....*
gi 1039751015 1967 KTKVESEIRKEYMEK 1981
Cdd:PHA02562   388 LDKIVKTKSELVKEK 402
PTZ00121 PTZ00121
MAEBL; Provisional
 717-1527 1.91e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 50.91  E-value: 1.91e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  717 KEISSLTQLSEEVKESAEEARSTLAA-VTEERDQLLYQVKELDVLAELRARVQELESSLAEAEKQRgldyESQRAQHNLL 795
Cdd:PTZ00121  1084 KEDNRADEATEEAFGKAEEAKKTETGkAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAE----DAKRVEIARK 1159

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  796 TEQIHSLSIEAKSKDV-KIEALQReldGVQLQFCEQGTQMKTLQSQLEAKEREVREGTERLRDISQEmeglSQALSQKEL 874
Cdd:PTZ00121  1160 AEDARKAEEARKAEDAkKAEAARK---AEEVRKAEELRKAEDARKAEAARKAEEERKAEEARKAEDA----KKAEAVKKA 1232

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  875 EIAKMDQllLEKQKDVETLQQTIQEKDQQVTELSFSMTEKMVQLNEEKFSLGVEIKTLKEQLNLLSRTEEATKEQVEESG 954
Cdd:PTZ00121  1233 EEAKKDA--EEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKK 1310

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  955 AGSSLKLGHDESGQEGLQQELELLRKESEQRKRKLQAALINRKELLQKVSQLEEELAKVREDSRKEIPFGENERRKLEED 1034
Cdd:PTZ00121  1311 AEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEK 1390

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1035 RENRDDPEEWGTSKWREVEASLKQTISEKEVELegiRRDLKEKTAAEEELQAVVQRMTRDLQSKTKQIDLLQEEVTENQA 1114
Cdd:PTZ00121  1391 KKADEAKKKAEEDKKKADELKKAAAAKKKADEA---KKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAE 1467

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1115 TIQKLVTGTMDAGNGGSAAPVKETAassppgaggEEHWKPELEGRILDLEKDKTQLQKKLQEALIARKAilKKAQEKEKq 1194
Cdd:PTZ00121  1468 EAKKADEAKKKAEEAKKADEAKKKA---------EEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEA--KKAEEAKK- 1535

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1195 lKEELREQKDAYHHLQGQFHEQNKEkeniADQLRQLQCQARESIDRQLPGTGQQEpgppapslegisLEDTEPASESDLH 1274
Cdd:PTZ00121  1536 -ADEAKKAEEKKKADELKKAEELKK----AEEKKKAEEAKKAEEDKNMALRKAEE------------AKKAEEARIEEVM 1598

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1275 AAQPSPPGETAALQATVSVAQIQAQLKEMEVEKEELELKVSSIASELAKKSEEVlllQDQINEQGLEIQNLKAASVEAQA 1354
Cdd:PTZ00121  1599 KLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEEL---KKAEEENKIKAAEEAKKAEEDKK 1675

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1355 HTELLKQELESSQLKVaglEHLKTLQPEldalhkhmGQKEEEVnylygQLSEKEQTLTTVQTEMVEQERLIKAlhTQLEM 1434
Cdd:PTZ00121  1676 KAEEAKKAEEDEKKAA---EALKKEAEE--------AKKAEEL-----KKKEAEEKKKAEELKKAEEENKIKA--EEAKK 1737

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1435 QAKEHEERLKQAQVEICElKKKPTELEEETNAKQQLQRKLQAALIsrKEALKENKSLQeqlssaRDAVERLTKSLADVES 1514
Cdd:PTZ00121  1738 EAEEDKKKAEEAKKDEEE-KKKIAHLKKEEEKKAEEIRKEKEAVI--EEELDEEDEKR------RMEVDKKIKDIFDNFA 1808

                          810
                   ....*....|...
gi 1039751015 1515 QVSVQNQEKDAVL 1527
Cdd:PTZ00121  1809 NIIEGGKEGNLVI 1821
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 153-934 2.17e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 50.45  E-value: 2.17e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  153 HELQEKEKLISSLQAQLDQSEQasQLDKSSAEMEDFVlmkQQLQEKEELISTLQTQLSQTQAEQAAQLSSMQQVVREKDA 232
Cdd:TIGR02169  230 KEKEALERQKEAIERQLASLEE--ELEKLTEEISELE---KRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIA 304

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  233 RFETQVRLHEDELLQLVTQsdvETEMQQKLRVMQRKLEEHEEALLGRAQVVDLLQKELTSAEQRNQVLSQQLQLLEAEHN 312
Cdd:TIGR02169  305 SLERSIAEKERELEDAEER---LAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFA 381

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  313 TLKNTMETERQE-SKTLMEKVELEVAERKL--SFHNLQEEMHQLQGQLERAGQAQADLEtqysalqqrhktemEEKTACI 389
Cdd:TIGR02169  382 ETRDELKDYREKlEKLKREINELKRELDRLqeELQRLSEELADLNAAIAGIEAKINELE--------------EEKEDKA 447

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  390 LSLQKNEQELQSACAALKEENSKLLQEKHDQaaesaqamRQLEDQLQQKSKEISQFVNKPNLQKNETASQTSLPDVNNEG 469
Cdd:TIGR02169  448 LEIKKQEWKLEQLAADLSKYEQELYDLKEEY--------DRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKAS 519

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  470 DQAVMeETVASLQKrvVELENEKGALLLSSGELEELKAENEKLSSRITLLEAQNRAGEAdgtvcevstagTTLLNRSDSS 549
Cdd:TIGR02169  520 IQGVH-GTVAQLGS--VGERYATAIEVAAGNRLNNVVVEDDAVAKEAIELLKRRKAGRA-----------TFLPLNKMRD 585

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  550 PEENGQAVLENTFSqkhkELSVLLVEMKEAQEEIAF-------LKSQLQGKRPEGDYEVLDRREVQLMESEGppSVTAGD 622
Cdd:TIGR02169  586 ERRDLSILSEDGVI----GFAVDLVEFDPKYEPAFKyvfgdtlVVEDIEAARRLMGKYRMVTLEGELFEKSG--AMTGGS 659

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  623 VlcAPSDESSGPAAEEEQAgmkdrhraseagplndagmELSSPKLDGVDKSLAVShvcqchQGELERLKTQVLELETSLH 702
Cdd:TIGR02169  660 R--APRGGILFSRSEPAEL-------------------QRLRERLEGLKRELSSL------QSELRRIENRLDELSQELS 712

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  703 TAEetykRNLSEKVKEISSLTQLSEEVKESAEEARSTLAAVTEERDQLLYQVKELD--------VLAELRARVQELESSL 774
Cdd:TIGR02169  713 DAS----RKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEarieeleeDLHKLEEALNDLEARL 788

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  775 AEAE-KQRGLDYESQRAQHNLLTEQIHSLSIEAKSKDVKIEALQRELDGVQLQFCEQGTQMKTLQSQLEAKEREVREGTE 853
Cdd:TIGR02169  789 SHSRiPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEE 868

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  854 RLRDISQEMEGLSQALSQKELEIAKMDQLLLEKQKDVETLQQTIQEKDQQVTELsfsmTEKMVQLNEEKFSLGVEIKTLK 933
Cdd:TIGR02169  869 ELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSEL----KAKLEALEEELSEIEDPKGEDE 944


                   .
gi 1039751015  934 E 934
Cdd:TIGR02169  945 E 945
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 2212-2961 2.88e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 50.07  E-value: 2.88e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2212 EEVRLKEENCIALKDQLRQmaiHMEELKITVSRLEHDKEIWESKAQTELQHHQKAYDKLQEENKELTSQLEDARQLYHDS 2291
Cdd:TIGR02169  180 EEVEENIERLDLIIDEKRQ---QLERLRREREKAERYQALLKEKREYEGYELLKEKEALERQKEAIERQLASLEEELEKL 256

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2292 KNELTKLESELKSLKDQTTDLNNSLEKCKEHE-NNLEGIIKQQEADIQNCKFSCEQLETDLAASRELTSRLHDEINAKEQ 2370
Cdd:TIGR02169  257 TEEISELEKRLEEIEQLLEELNKKIKDLGEEEqLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLA 336

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2371 KIISLlSGKEEAIQLAVEELhqqhSKEIKELENLLSQEEEENVALEEENKRALEKTNQLTEALEAIKKEsfeqkaqldsf 2450
Cdd:TIGR02169  337 EIEEL-EREIEEERKRRDKL----TEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKRE----------- 400

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2451 vksMSSLQDDRDRIVSDYRQLEERhlsaILEKDQLIQDAAAENNKLKEEMRGLRshmddlnsenakldAELVQYRRDLNE 2530
Cdd:TIGR02169  401 ---INELKRELDRLQEELQRLSEE----LADLNAAIAGIEAKINELEEEKEDKA--------------LEIKKQEWKLEQ 459

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2531 VIAIKDSQQKQLLDAQLQQNKeLRNECTKLEERLKGLEAEKQSL---QMSSDALQKEKQGLSKEIKNLQTQLTALQEEGT 2607
Cdd:TIGR02169  460 LAADLSKYEQELYDLKEEYDR-VEKELSKLQRELAEAEAQARASeerVRGGRAVEEVLKASIQGVHGTVAQLGSVGERYA 538

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2608 LGVYHA---QLKA----------------KEEELQRLN-MALSSSQKRTADLEEELVCVQKEATRKVSEIEDQLKKELKH 2667
Cdd:TIGR02169  539 TAIEVAagnRLNNvvveddavakeaiellKRRKAGRATfLPLNKMRDERRDLSILSEDGVIGFAVDLVEFDPKYEPAFKY 618

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2668 LHHDAGIMRNeTETAEE-----RVAELARDLVE----------MEQKLLTVTKENKD----LMAQIQAFGRSMSSLQDSR 2728
Cdd:TIGR02169  619 VFGDTLVVED-IEAARRlmgkyRMVTLEGELFEksgamtggsrAPRGGILFSRSEPAelqrLRERLEGLKRELSSLQSEL 697

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2729 DHATEELGDLKKKYDASLKELAQL-KEWQDSSREGDVLSQAAfplstsENVLSRLEKLNQQLTSKDEQLLHLSSELESSH 2807
Cdd:TIGR02169  698 RRIENRLDELSQELSDASRKIGEIeKEIEQLEQEEEKLKERL------EELEEDLSSLEQEIENVKSELKELEARIEELE 771

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2808 NQVQSISKAMTSLQNERDRlwselEKFRKSEEgKQRAAAPSAASSPAEVQSLKKAMSSLQNDRDRLLKELKNLQQQylqm 2887
Cdd:TIGR02169  772 EDLHKLEEALNDLEARLSH-----SRIPEIQA-ELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQ---- 841

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1039751015 2888 sqemteLRPLKAQLQESQDQTKALQVMEEELRQENLSWQHELRQLRMEKNSWELHERRMKEQfLMAISDKDQQL 2961
Cdd:TIGR02169  842 ------RIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQ-LRELERKIEEL 908
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
156-365 2.89e-05

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 50.02  E-value: 2.89e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  156 QEKEKLISSLQAQLDQSEQasQLDKSSAEMEDF------VLMKQQLQEKEELISTLQTQLSQTQAEQAAQLSSMQQVVRE 229
Cdd:COG3206    171 EEARKALEFLEEQLPELRK--ELEEAEAALEEFrqknglVDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQ 248

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  230 KDARFETQVRLHEDELLQLVTQSDVETEmQQKLRVMQRKLEEHEEALLGRAQVVDLLQKELTSAEQRNQVLSQQLQLLEA 309
Cdd:COG3206    249 LGSGPDALPELLQSPVIQQLRAQLAELE-AELAELSARYTPNHPDVIALRAQIAALRAQLQQEAQRILASLEAELEALQA 327

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1039751015  310 EHNTLKNTMETERQESKTLMEK-VELEVAERKLSfhNLQEEMHQLQGQLERAGQAQA 365
Cdd:COG3206    328 REASLQAQLAQLEARLAELPELeAELRRLEREVE--VARELYESLLQRLEEARLAEA 382
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 51-521 3.06e-05

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 49.94  E-value: 3.06e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015   51 EDALHRLAEAEKLVVELKDIISQKDVQLQQKDEALQEEKKAAENKIKKIKLHAKAKIMSLNKHMEEIKTQGGAALPPEAQ 130
Cdd:COG1196    315 EERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRA 394

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  131 AEELSKH---------NKSSTEEEMEIEKIKHELQEKEKLISSLQAQLDQSEQASQLDKSSAEMEDFVLMKQQLQEKEEL 201
Cdd:COG1196    395 AAELAAQleeleeaeeALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAAL 474

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  202 ISTLQTQLSQTQAEQAAQLSSMQQVVREKDARFETQVRLHEDELLQLVTQsdVETEMQQKLRVMQRKLEEHEEALLGRAQ 281
Cdd:COG1196    475 LEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAG--AVAVLIGVEAAYEAALEAALAAALQNIV 552

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  282 VVDLLQKE------------------LTSAEQRNQVLSQQLQLLEAEHNTLKNTMETERQESKTLMEKVELEVAERKLSF 343
Cdd:COG1196    553 VEDDEVAAaaieylkaakagratflpLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARL 632

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  344 HNLQEEMHQLQGQLERAGQAQADLETQYSALQQRHKTEMEEktacILSLQKNEQELQSACAALKEENSKLLQEKHDQAAE 423
Cdd:COG1196    633 EAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAA----LLEAEAELEELAERLAEEELELEEALLAEEEEERE 708

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  424 SAQAMRQLEDQLQQKSKEISQfVNKPNLQKNETASQTSLPDVNNEGDQAVMEETVASLQKRVVELENEKGAL----LLSS 499
Cdd:COG1196    709 LAEAEEERLEEELEEEALEEQ-LEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEALgpvnLLAI 787

                          490       500
                   ....*....|....*....|..
gi 1039751015  500 GELEELKAENEKLSSRITLLEA 521
Cdd:COG1196    788 EEYEELEERYDFLSEQREDLEE 809
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1813-2554 3.11e-05

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 50.12  E-value: 3.11e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1813 VSETFSSHDDIKNYLQQ-LDQLKGRIAELEMEKQK----DRELSQALENEKNALLTQISAKDSELKLLEEEVTKRTTLNQ 1887
Cdd:pfam15921   94 LNESNELHEKQKFYLRQsVIDLQTKLQEMQMERDAmadiRRRESQSQEDLRNQLQNTVHELEAAKCLKEDMLEDSNTQIE 173

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1888 QIQEELCRVTKLKETAEEEKDDLEERLMNQLAELNGSIGNYYQDVTDAQIKN-EQLESEMRNLQRCVSELEEEKQQLVKE 1966
Cdd:pfam15921  174 QLRKMMLSHEGVLQEIRSILVDFEEASGKKIYEHDSMSTMHFRSLGSAISKIlRELDTEISYLKGRIFPVEDQLEALKSE 253

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1967 ------------KTKVESEIRKEYMEKIQGAQKGPANKSHAKELQELLREKQQEVKQLQKdciRYLERISALEKTVKALE 2034
Cdd:pfam15921  254 sqnkielllqqhQDRIEQLISEHEVEITGLTEKASSARSQANSIQSQLEIIQEQARNQNS---MYMRQLSDLESTVSQLR 330

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2035 FVHTESQK----DLDVTKGNLAQAVEHRKKAQAELSSFKILLDDTQSEAARVLADNLKLKKELQSNKESIKsqiKQKDED 2110
Cdd:pfam15921  331 SELREAKRmyedKIEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLADLHKREKELSLEKEQNK---RLWDRD 407

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2111 LLRRLEQAEEKHRKEKKNMQekldaLHREKAHVEETLAEIQVSLtrkDQEMKELQGSlDSTLAQLAAFTKSMSSLQDDRD 2190
Cdd:pfam15921  408 TGNSITIDHLRRELDDRNME-----VQRLEALLKAMKSECQGQM---ERQMAAIQGK-NESLEKVSSLTAQLESTKEMLR 478

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2191 RVIDE--AKKW-----ERRFGD---AIQTKEEEVRLKEENCIALK-----------------DQLRQMAIHMEELKITVS 2243
Cdd:pfam15921  479 KVVEEltAKKMtlessERTVSDltaSLQEKERAIEATNAEITKLRsrvdlklqelqhlknegDHLRNVQTECEALKLQMA 558

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2244 RLEHDKEIWESKAQTELQ---HHQKAYDKLQEENKELTSQLEDARQLYHDSKNELTKLESELKSLKDQTTDLnnSLEKCK 2320
Cdd:pfam15921  559 EKDKVIEILRQQIENMTQlvgQHGRTAGAMQVEKAQLEKEINDRRLELQEFKILKDKKDAKIRELEARVSDL--ELEKVK 636

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2321 ehennLEGIIKQQEADIQNCKFSCEQLETDLAASRELTSRLHDEINAKEQKiislLSGKEEAIQLAVEELHQQHSKEIKE 2400
Cdd:pfam15921  637 -----LVNAGSERLRAVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRN----FRNKSEEMETTTNKLKMQLKSAQSE 707

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2401 LENLLSQEEEENVALEEENKRALEKTNQLTEaleaikkesfeQKAQLDSFVKSMSSLQDDRDRIVSDYRQLEErhlsail 2480
Cdd:pfam15921  708 LEQTRNTLKSMEGSDGHAMKVAMGMQKQITA-----------KRGQIDALQSKIQFLEEAMTNANKEKHFLKE------- 769

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1039751015 2481 EKDQLIQD---AAAENNKLKEEMRGLRSHMDDLNSENAKLDAELVQYRRDLNEVIAIKDSQQKQLLDAQLQQNKELR 2554
Cdd:pfam15921  770 EKNKLSQElstVATEKNKMAGELEVLRSQERRLKEKVANMEVALDKASLQFAECQDIIQRQEQESVRLKLQHTLDVK 846
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 1430-2246 3.41e-05

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 50.05  E-value: 3.41e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1430 TQLEMQAKEHEERLKQAQVEICELKKKPTELEEETNAKQQLQRKLQAALISRKEALKENKSLQEQL-------------- 1495
Cdd:TIGR00606  227 TSKEAQLESSREIVKSYENELDPLKNRLKEIEHNLSKIMKLDNEIKALKSRKKQMEKDNSELELKMekvfqgtdeqlndl 306

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1496 -----SSARDAVERLT---KSLADVESQVSVQNQEKDAVLGKLTILQEERDKLIAEMDRFLLENQSLSGSCESLKLALGG 1567
Cdd:TIGR00606  307 yhnhqRTVREKERELVdcqRELEKLNKERRLLNQEKTELLVEQGRLQLQADRHQEHIRARDSLIQSLATRLELDGFERGP 386

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1568 LTEDKEKLMEELESVRSSKMAES------------TEWQEKHKELQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQEL 1635
Cdd:TIGR00606  387 FSERQIKNFHTLVIERQEDEAKTaaqlcadlqskeRLKQEQADEIRDEKKGLGRTIELKKEILEKKQEELKFVIKELQQL 466

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1636 YAKLRSTESDKREREKQLQDAEQEME----EMKEKMRKFAKSKQQKILELEEENDRLRAEAQPVGGTGESMEALLSSNSS 1711
Cdd:TIGR00606  467 EGSSDRILELDQELRKAERELSKAEKnsltETLKKEVKSLQNEKADLDRKLRKLDQEMEQLNHHTTTRTQMEMLTKDKMD 546

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1712 LKEELEKITLEH--------------KTLSKEFEALMAEKDALSEETRNLKLQVEAQVLKQASLEATEKSDEPKDV---- 1773
Cdd:TIGR00606  547 KDEQIRKIKSRHsdeltsllgyfpnkKQLEDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSsyed 626

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1774 --------------IEEVTQAVVGKSQERDALSDSAKLEDS---EAILMGDGAKPGVSETFSSHDDIKNYLQQLdQLKGR 1836
Cdd:TIGR00606  627 klfdvcgsqdeesdLERLKEEIEKSSKQRAMLAGATAVYSQfitQLTDENQSCCPVCQRVFQTEAELQEFISDL-QSKLR 705

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1837 IAELEMEKQKdrELSQALENEKNALLTQISAKDSELKLLEEEVTKRTTLNQQIQEELCRVTKLKETAEEEKDDL--EERL 1914
Cdd:TIGR00606  706 LAPDKLKSTE--SELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTImpEEES 783

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1915 MNQLAELNGSIGNYYQDVTDAQIKNEQLESEMR--NLQRCVSELEEEKQQLVKEKTKVESEIR------KEYMEKIQGAQ 1986
Cdd:TIGR00606  784 AKVCLTDVTIMERFQMELKDVERKIAQQAAKLQgsDLDRTVQQVNQEKQEKQHELDTVVSKIElnrkliQDQQEQIQHLK 863

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1987 -KGPANKSHAKELQELLREKQQEVKQLQKDCIRYLERISALEKTVKALEFVHTESQKDLDVTKGNLAQAVEHRKKAQAEl 2065
Cdd:TIGR00606  864 sKTNELKSEKLQIGTNLQRRQQFEEQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEELISSKETSNKKAQDK- 942

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2066 ssfkilLDDTQSEAARVLADNLKLKKELQSNKESIKSQIKQKDEDLLRRLEQAEEKHRKEKKNMQEKLDALhrEKAHVEE 2145
Cdd:TIGR00606  943 ------VNDIKEKVKNIHGYMKDIENKIQDGKDDYLKQKETELNTVNAQLEECEKHQEKINEDMRLMRQDI--DTQKIQE 1014

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2146 TLAEIQVSLTRKDQEMKELQGSLDSTLAQLA-----AFTKSMSSLQDDRDRV-IDEAKKWERRFGDAIQTKEEEVRLKEE 2219
Cdd:TIGR00606 1015 RWLQDNLTLRKRENELKEVEEELKQHLKEMGqmqvlQMKQEHQKLEENIDLIkRNHVLALGRQKGYEKEIKHFKKELREP 1094

                          890       900
                   ....*....|....*....|....*..
gi 1039751015 2220 NCIALKDQLRQMAIHMEELKITVSRLE 2246
Cdd:TIGR00606 1095 QFRDAEEKYREMMIVMRTTELVNKDLD 1121
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2392-2605 3.68e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 48.99  E-value: 3.68e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2392 QQHSKEIKELENLLSQEEEENVALEEENKRALEKTNQLTEALEAIKKESFEQKAQLDSFVKSMSSLQDDRD--------R 2463
Cdd:COG4942     30 EQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEaqkeelaeL 109

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2464 IVSDYRQLEERHLSAILEKDQlIQDAAAENNKLKEEMRGLRSHMDDLNSENAKLdaelvqyrRDLNEVIAIKDSQQKQLL 2543
Cdd:COG4942    110 LRALYRLGRQPPLALLLSPED-FLDAVRRLQYLKYLAPARREQAEELRADLAEL--------AALRAELEAERAELEALL 180

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1039751015 2544 DAQLQQNKELRNECTKLEERLKGLEAEKQSLQMSSDALQKEKQGLSKEIKNLQTQLTALQEE 2605
Cdd:COG4942    181 AELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1608-2272 4.12e-05

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 49.68  E-value: 4.12e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1608 LQSYENVSNEAERIQHVVESVRQEKQELYAKLRSTESDKREREKQLQDAEQEMeemkekmrkfaKSKQQKILELEEENDR 1687
Cdd:PRK03918   157 LDDYENAYKNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREI-----------NEISSELPELREELEK 225

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1688 LRAEaqpvggtgesmeallssnsslKEELEKITLEHKTLSKEFEALMAEKDALSEETRNLKLQVEAQVLKQASLEatEKS 1767
Cdd:PRK03918   226 LEKE---------------------VKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELE--EKV 282

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1768 DEPKDVIEEVTQAVVGKSQERDALSDSAKLEDSEAILMgdgakpgvsetfSSHDDIKNYLQQLDQLKGRIAELEMEKQKD 1847
Cdd:PRK03918   283 KELKELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLE------------EEINGIEERIKELEEKEERLEELKKKLKEL 350

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1848 RELSQALEnEKNALLTQISAKDSELKLLEEEVTKRTTlnQQIQEELCRVTKLKETAEEEKDDLEERlmnqlaelngsIGN 1927
Cdd:PRK03918   351 EKRLEELE-ERHELYEEAKAKKEELERLKKRLTGLTP--EKLEKELEELEKAKEEIEEEISKITAR-----------IGE 416

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1928 YYQDVTDAQIKNEQLESEMRNLQRCVSEL-EEEKQQLVKEKTKVESEIRKEymekiqgaqkgpankshAKELQELLREKQ 2006
Cdd:PRK03918   417 LKKEIKELKKAIEELKKAKGKCPVCGRELtEEHRKELLEEYTAELKRIEKE-----------------LKEIEEKERKLR 479

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2007 QEVKQLQKDcIRYLERISALEKTVKALEFVHTESQKdldvtkgnlaQAVEHRKKAQAELSSFKILLDDTQSEaARVLADN 2086
Cdd:PRK03918   480 KELRELEKV-LKKESELIKLKELAEQLKELEEKLKK----------YNLEELEKKAEEYEKLKEKLIKLKGE-IKSLKKE 547

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2087 LKLKKELQSNKESIKSQIKQKDEDLLRRLEQAEEKHRKEKKNMQEKLDALhrEKAHVEE-TLAEIQVSLTRKDQEMKELQ 2165
Cdd:PRK03918   548 LEKLEELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERLKEL--EPFYNEYlELKDAEKELEREEKELKKLE 625

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2166 GSLDSTLAQLAAFTKSMSSLQDDrdrvIDEAKKweRRFGDAIQTKEEEVRLKEENCIALKDQLRQMAIHMEELKITVSRL 2245
Cdd:PRK03918   626 EELDKAFEELAETEKRLEELRKE----LEELEK--KYSEEEYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKL 699

                          650       660
                   ....*....|....*....|....*..
gi 1039751015 2246 EHDKEIWEsKAQTELQHHQKAYDKLQE 2272
Cdd:PRK03918   700 KEELEERE-KAKKELEKLEKALERVEE 725
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1155-1631 4.22e-05

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 49.65  E-value: 4.22e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1155 ELEGRILDLEKDKTQLQKKLQEAliarKAILKKAQEKekqlKEELREQKDAYHHLQGQFHEQNKEKENIADQLRQLQCQA 1234
Cdd:PRK02224   217 ELDEEIERYEEQREQARETRDEA----DEVLEEHEER----REELETLEAEIEDLRETIAETEREREELAEEVRDLRERL 288

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1235 ---RESIDRQLPGTGQQEPGPPAPSLEGISLEDTEPASESDLHAAQPSPPG-ETAALQATVSVAQIQAQLKEMEVEKEEL 1310
Cdd:PRK02224   289 eelEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQAhNEEAESLREDADDLEERAEELREEAAEL 368

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1311 ELKVSSIASELAKKSEEVLLLQDQINEQGLEIQNLKAASVEAQAHTELLKQELESSQLKVAGLE-HLKTL---------- 1379
Cdd:PRK02224   369 ESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAELEaTLRTArerveeaeal 448

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1380 ----------QPELDALH-KHMGQKEEEVNYLYGQLSEKEQTLTTVQ------TEMVEQERLIKALHTQLEMQAK---EH 1439
Cdd:PRK02224   449 leagkcpecgQPVEGSPHvETIEEDRERVEELEAELEDLEEEVEEVEerleraEDLVEAEDRIERLEERREDLEEliaER 528

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1440 EERLKQAQVEICELKKKPTELEEETNAKQQLQRKLQAALISRKEALKENKSLQEQLSSARDAVERLTKSLADVES--QVS 1517
Cdd:PRK02224   529 RETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLERIRTLLAAIADaeDEI 608

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1518 VQNQEKDAVLG--------KLTILQEERDKLIAEMDRFLLEN-----QSLSGSCESLKLALGGLTEDKEKLMEELESVRS 1584
Cdd:PRK02224   609 ERLREKREALAelnderreRLAEKRERKRELEAEFDEARIEEaredkERAEEYLEQVEEKLDELREERDDLQAEIGAVEN 688

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|....*..
gi 1039751015 1585 SkMAESTEWQEKHKELQKEYEVLlqsyENVSNEAERIQHVVESVRQE 1631
Cdd:PRK02224   689 E-LEELEELRERREALENRVEAL----EALYDEAEELESMYGDLRAE 730
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1148-2014 4.29e-05

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 49.58  E-value: 4.29e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1148 GEEHWKPELEGRILDLEKDKTQLQKKLQEALIARKAILKKAQEKEKQLKEELREQKDAYHHLQGQFHEQNKEKENIADQL 1227
Cdd:pfam02463  152 PERRLEIEEEAAGSRLKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDY 231

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1228 RQLQCQARESIDRQLPGTGQQEPGPPAPSLEGISLEDTEPASESDLHAAQPSppGETAALQATVSVAQIQAQLKEMEVEK 1307
Cdd:pfam02463  232 LKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKL--QEEELKLLAKEEEELKSELLKLERRK 309

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1308 EELELKVSSIASELAKKSEEVLLLQDQINEQGLEIQNLKAASveaqahTELLKQELESSQLKVAGLEHLKTLQPELDALH 1387
Cdd:pfam02463  310 VDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKR------EAEEEEEEELEKLQEKLEQLEEELLAKKKLES 383

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1388 KHMGQKEEEVNYLYGQLSEKEQTLTTVQTEMVEQERLIKALHTQLEMQAKEhEERLKQAQVEICELKKKPTELEEETNAK 1467
Cdd:pfam02463  384 ERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEE-EEESIELKQGKLTEEKEELEKQELKLLK 462

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1468 QQLQRKLQAALISRKEALKENKSLQEQLSSARDAvERLTKSLADVESQVSVQNQEKDAVLGKLTILQEERDKLIAEMDRF 1547
Cdd:pfam02463  463 DELELKKSEDLLKETQLVKLQEQLELLLSRQKLE-ERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENY 541

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1548 LLENQSL-----------SGSCESLKLALGGLTEDKEKLMEELESVRSSKMAESTEWQEKHKELQKEYEVLLQSYENVSN 1616
Cdd:pfam02463  542 KVAISTAvivevsatadeVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKR 621

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1617 EAERIQHVVESVRQEKQELYAKLRSTESDKREREKQLQDAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEAQPVG 1696
Cdd:pfam02463  622 AKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEI 701

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1697 GTGESMEALLSSNSSLKEE---LEKITLEHKTLSKEFEALMAEKDALSEETRNLKLQVEAQVLKQASLEATEKSDEPKDV 1773
Cdd:pfam02463  702 KKKEQREKEELKKLKLEAEellADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEERE 781

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1774 IEEVtqavvgKSQERDALSDSAKLEDSEAILMgdgakpgvsetfsSHDDIKNYLQQLDQLKGRIAELEMEKQKDRELSQA 1853
Cdd:pfam02463  782 KTEK------LKVEEEKEEKLKAQEEELRALE-------------EELKEEAELLEEEQLLIEQEEKIKEEELEELALEL 842

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1854 LENEKNALLTQISAKDSELKLLEEEVTKRTTLNQQIQEELCRVTKLKETAEEEKDDLEERLMNQLAELNgsiGNYYQDVT 1933
Cdd:pfam02463  843 KEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNL---LEEKENEI 919

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1934 DAQIKNEQLESEMRNLQRCVSELEEEKQQLVKEKTKVESEIRKEYMEKiQGAQKGPANKSHAKELQELLREKQQEVKQLQ 2013
Cdd:pfam02463  920 EERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRLLL-AKEELGKVNLMAIEEFEEKEERYNKDELEKE 998


                   .
gi 1039751015 2014 K 2014
Cdd:pfam02463  999 R 999
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
2479-2736 4.35e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 49.53  E-value: 4.35e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2479 ILEKDQLIQDAAAennkLKEEMRGLRSHMDDLNSENAKLDA--ELVQYRRDLNEVIAIKDSQQKQLLDAQLQQNKE---- 2552
Cdd:COG4913    217 MLEEPDTFEAADA----LVEHFDDLERAHEALEDAREQIELlePIRELAERYAAARERLAELEYLRAALRLWFAQRrlel 292

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2553 LRNECTKLEERLKGLEAEKQSLQMSSDALQKEKQGLSKEIKNLQTQ-LTALQEEgtlgvyhaqLKAKEEELQRLNMALSS 2631
Cdd:COG4913    293 LEAELEELRAELARLEAELERLEARLDALREELDELEAQIRGNGGDrLEQLERE---------IERLERELEERERRRAR 363

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2632 SQKRTADLEEELVCVQKEATRKVSEIEDQLkkelkhlhhdagimrnetETAEERVAELARDLVEMEQKLLTVTKENKDLM 2711
Cdd:COG4913    364 LEALLAALGLPLPASAEEFAALRAEAAALL------------------EALEEELEALEEALAEAEAALRDLRRELRELE 425

                          250       260
                   ....*....|....*....|....*....
gi 1039751015 2712 AQIQAFGRSMSS----LQDSRDHATEELG 2736
Cdd:COG4913    426 AEIASLERRKSNiparLLALRDALAEALG 454
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1988-2202 4.54e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 48.61  E-value: 4.54e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1988 GPANKSHAKELQELLREKQQEVKQLQKDCIRYLERISALEKTVKALEFVHTESQKDLDVTKGNLAQAVEHRKKAQAELSS 2067
Cdd:COG4942     15 AAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAE 94

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2068 FKILLDDTQSEAARVLA--------DNLKLKKELQSNKESIKS-----QIKQKDEDLLRRLEQAEEKHRKEKKNMQEKLD 2134
Cdd:COG4942     95 LRAELEAQKEELAELLRalyrlgrqPPLALLLSPEDFLDAVRRlqylkYLAPARREQAEELRADLAELAALRAELEAERA 174

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1039751015 2135 ALHREKAHVEETLAEIQVSLTRKDQEMKELQGSLDSTLAQLAAFTKSMSSLQDDRDRVIDEAKKWERR 2202
Cdd:COG4942    175 ELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 2477-3057 4.89e-05

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 49.45  E-value: 4.89e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2477 SAILEKDQLIQDAAAENNKLKEEMRGLRSHM----DDLNSENAKLDAELVQYRRDLNEViaikDSQQKQLLDAQLQQNK- 2551
Cdd:pfam12128  269 SDETLIASRQEERQETSAELNQLLRTLDDQWkekrDELNGELSAADAAVAKDRSELEAL----EDQHGAFLDADIETAAa 344

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2552 ------ELRNECTKLEERLKGLEAEKQSLQMSSDAL-QKEKQGLSKEIKNLQTQLTALQEEGTLG------VYHAQLKAK 2618
Cdd:pfam12128  345 dqeqlpSWQSELENLEERLKALTGKHQDVTAKYNRRrSKIKEQNNRDIAGIKDKLAKIREARDRQlavaedDLQALESEL 424

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2619 EEELQRLNMALSSSQKRTADLEEELVCVQKEATRKVSEIEDQLKK--ELKHLHHDAGIMRNETETA--EERVAELARD-- 2692
Cdd:pfam12128  425 REQLEAGKLEFNEEEYRLKSRLGELKLRLNQATATPELLLQLENFdeRIERAREEQEAANAEVERLqsELRQARKRRDqa 504

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2693 ---LVEMEQKLLTVTKENKDLMAQIqaFGRSMSSLQDSRDHATEELGDLKKKYDASLKELAQLKEWQDSSREGDVLSQAA 2769
Cdd:pfam12128  505 seaLRQASRRLEERQSALDELELQL--FPQAGTLLHFLRKEAPDWEQSIGKVISPELLHRTDLDPEVWDGSVGGELNLYG 582

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2770 FPLSTSENVLSRLEKLNQQLTSKDEQllhLSSELESSHNQVQSISKAMTSLQNERDRLWSELEkfrkseegkqraaapsa 2849
Cdd:pfam12128  583 VKLDLKRIDVPEWAASEEELRERLDK---AEEALQSAREKQAAAEEQLVQANGELEKASREET----------------- 642

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2850 asspaevqslkKAMSSLQNDRDRlLKELKNLQQQYLQMSQEMTELRPLKAQlQESQDQTKALQVMEEELRQENLSWQHEL 2929
Cdd:pfam12128  643 -----------FARTALKNARLD-LRRLFDEKQSEKDKKNKALAERKDSAN-ERLNSLEAQLKQLDKKHQAWLEEQKEQK 709

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2930 RQLRMEKNswelherrmkEQFLMAISDKDQQLGHLQSLLRELRSSSQAQI--LSTQYQRQAspetsASLDGSQKLVYETE 3007
Cdd:pfam12128  710 REARTEKQ----------AYWQVVEGALDAQLALLKAAIAARRSGAKAELkaLETWYKRDL-----ASLGVDPDVIAKLK 774

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1039751015 3008 LLRTQLNDSLKEIHQKELRIQQLNSKF-SQLLEEKNVLSTQLSDASQSLRE 3057
Cdd:pfam12128  775 REIRTLERKIERIAVRRQEVLRYFDWYqETWLQRRPRLATQLSNIERAISE 825
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1341-1760 5.24e-05

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 49.00  E-value: 5.24e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1341 EIQNLKAASVEAQAHTELLKQELESSQLKVAGLEHLKTLQPELDALHKHmGQKEEEVNYLYGQLSEKEQTLTTVQTEMVE 1420
Cdd:COG4717     89 EYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEAL-EAELAELPERLEELEERLEELRELEEELEE 167

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1421 QERLIKALHTQLEMQAK----EHEERLKQAQVEICELKKKPTELEEETNAKQQLQRKLQAA---LISRKEALKENKSLQE 1493
Cdd:COG4717    168 LEAELAELQEELEELLEqlslATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEEleqLENELEAAALEERLKE 247

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1494 QLSSARDAVERLTKSLADVESQVSVQNQEKDAVLG-------------KLTILQEERDKLIAEMDRFLLENQSLSGSCES 1560
Cdd:COG4717    248 ARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVlgllallflllarEKASLGKEAEELQALPALEELEEEELEELLAA 327

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1561 LKLALGGLTEDKEKLMEELESVRSS-KMAESTEWQEKHKELQKEYEVLLQSYeNVSNEAERIQHVVESvrQEKQELYAKL 1639
Cdd:COG4717    328 LGLPPDLSPEELLELLDRIEELQELlREAEELEEELQLEELEQEIAALLAEA-GVEDEEELRAALEQA--EEYQELKEEL 404

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1640 RSTESDKREREKQLQDAEQEMEEMKEKMRkfAKSKQQKILELEEENDRLRAEaqpVGGTGESMEALLSSN--SSLKEELE 1717
Cdd:COG4717    405 EELEEQLEELLGELEELLEALDEEELEEE--LEELEEELEELEEELEELREE---LAELEAELEQLEEDGelAELLQELE 479

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|...
gi 1039751015 1718 KITLEHKTLSKEFEALMAEKDALSEETRNLKLQVEAQVLKQAS 1760
Cdd:COG4717    480 ELKAELRELAEEWAALKLALELLEEAREEYREERLPPVLERAS 522
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2424-2642 6.47e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 48.22  E-value: 6.47e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2424 EKTNQLTEALEAIKKESFEQKAQLDSFVKSMSSLQDDRDRIVSDYRQLEERhlsailekdqlIQDAAAENNKLKEEMRGL 2503
Cdd:COG4942     27 AELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQE-----------LAALEAELAELEKEIAEL 95

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2504 RSHMDDLNSENAKLDAELVQYRR--DLNEVIAIKDSQQ--------KQLLDAQLQQNKELRNECTKLEERLKGLEAEKQS 2573
Cdd:COG4942     96 RAELEAQKEELAELLRALYRLGRqpPLALLLSPEDFLDavrrlqylKYLAPARREQAEELRADLAELAALRAELEAERAE 175

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1039751015 2574 LQMSSDALQKEKQGLSKEIKNLQTQLTALQEEgtLGVYHAQLKAKEEELQRLNMALSSSQKRTADLEEE 2642
Cdd:COG4942    176 LEALLAELEEERAALEALKAERQKLLARLEKE--LAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1585-2154 7.75e-05

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 48.50  E-value: 7.75e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1585 SKMAESTEwQEKHKELQKEYEVllqsyeNVSNEAERIQHVVESVRQEKQELYAKLRSTESDKREREKQLQDAEQEmeemk 1664
Cdd:PRK02224   213 SELAELDE-EIERYEEQREQAR------ETRDEADEVLEEHEERREELETLEAEIEDLRETIAETEREREELAEE----- 280

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1665 ekmrkfAKSKQQKILELEEENDRLRAEAQPVGGTGESMEALLSSNSSLKEELEKITLEHKTLSKEF--EALMAEKDALSE 1742
Cdd:PRK02224   281 ------VRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQAHneEAESLREDADDL 354

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1743 ETRNLKLQVEAQVLKQASLEATEKSDEPKDVIEEVtqavvgksqERDALSDSAKLEDSEAILmgDGAKPGVSETFSSHDD 1822
Cdd:PRK02224   355 EERAEELREEAAELESELEEAREAVEDRREEIEEL---------EEEIEELRERFGDAPVDL--GNAEDFLEELREERDE 423

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1823 IKNYLQQLD----QLKGRIAELE--MEKQKDRELSQALENEKNAllTQISAKDSELKLLEEEVTKRTTLNQQIQEELCRV 1896
Cdd:PRK02224   424 LREREAELEatlrTARERVEEAEalLEAGKCPECGQPVEGSPHV--ETIEEDRERVEELEAELEDLEEEVEEVEERLERA 501

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1897 TKLKETA------EEEKDDLEERLMNQLAELNgsignyyQDVTDAQIKNEQ---LESEMRNLQRCVSELEEEKQQlVKEK 1967
Cdd:PRK02224   502 EDLVEAEdrierlEERREDLEELIAERRETIE-------EKRERAEELRERaaeLEAEAEEKREAAAEAEEEAEE-AREE 573

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1968 TKVESEIRKEYMEKIQGAQKGPANKSHAKELQELLREKQQEVKQLQKDCIRYLERISALEKTVKALEFVHTESqkdldvt 2047
Cdd:PRK02224   574 VAELNSKLAELKERIESLERIRTLLAAIADAEDEIERLREKREALAELNDERRERLAEKRERKRELEAEFDEA------- 646

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2048 kgNLAQAVEHRKKAQAELSSFKILLDDTQSEaarvladnlklKKELQSNKESIKSQIKQKdEDLLRRLEQAEEKHrkekk 2127
Cdd:PRK02224   647 --RIEEAREDKERAEEYLEQVEEKLDELREE-----------RDDLQAEIGAVENELEEL-EELRERREALENRV----- 707

                          570       580
                   ....*....|....*....|....*..
gi 1039751015 2128 nmqEKLDALHREKAHVEETLAEIQVSL 2154
Cdd:PRK02224   708 ---EALEALYDEAEELESMYGDLRAEL 731
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 2686-3040 8.62e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 48.53  E-value: 8.62e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2686 VAELARDLVEMEQKLLTVTKENKDLMAQIQAFGRSMSSLQDSRDHATEELGDLKKKYDASLKELaqLKEWQDSSREgdvl 2765
Cdd:TIGR02169  165 VAEFDRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAERYQALLKEKREYEGYEL--LKEKEALERQ---- 238

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2766 sqaafpLSTSENVLSRLEKLNQQLTSKDEQLLHLSSELESSHNQVQSISKAMTSlqNERDRLWSELEKFrkseEGKQRAA 2845
Cdd:TIGR02169  239 ------KEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGE--EEQLRVKEKIGEL----EAEIASL 306

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2846 APSAASSPAEVQSLKKAMSSLQNDRDRLLKELKNL----QQQYLQMSQEMTELRPLKAQLQESQDQTKALQVMEEELRQE 2921
Cdd:TIGR02169  307 ERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELereiEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDE 386

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2922 NLSWQHELRQLRMEKNSWELHERRM---KEQFLMAISDKDQQLGHLQSLLRELRSSSQAQILSTQYQRQASPETSASLDG 2998
Cdd:TIGR02169  387 LKDYREKLEKLKREINELKRELDRLqeeLQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSK 466

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|..
gi 1039751015 2999 SQKLVYEtelLRTQLNDSLKEIHQKELRIQQLNSKFSQLLEE 3040
Cdd:TIGR02169  467 YEQELYD---LKEEYDRVEKELSKLQRELAEAEAQARASEER 505
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
684-1043 9.11e-05

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 48.50  E-value: 9.11e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  684 QGELERLKTQVLELETSLHTAEETYKRNLsekvKEISSLTQLSEEVKESAEEARSTLAAVTEERDQLLYQVKELDV-LAE 762
Cdd:PRK02224   320 EDRDEELRDRLEECRVAAQAHNEEAESLR----EDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEeIEE 395

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  763 LRARVQELESSLAEAEKQRgldyESQRAQHNLLTEQIHSLSIEAKSKDVKIEALQRELDGVQLQFCEQGTQMKTLQSQLE 842
Cdd:PRK02224   396 LRERFGDAPVDLGNAEDFL----EELREERDELREREAELEATLRTARERVEEAEALLEAGKCPECGQPVEGSPHVETIE 471

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  843 AKEREVREGTERLRDISQEMEGLSQALSQKE--LEIAKMDQLLLEKQKDVETL-----------QQTIQEKDQQVTELSF 909
Cdd:PRK02224   472 EDRERVEELEAELEDLEEEVEEVEERLERAEdlVEAEDRIERLEERREDLEELiaerretieekRERAEELRERAAELEA 551

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  910 SMTEKMVQ---LNEEKFSLGVEIKTLKEQLNLLSRTEEATkEQVEESGAGSSLKLGHDESGQEGLQQ--ELELLRKE--S 982
Cdd:PRK02224   552 EAEEKREAaaeAEEEAEEAREEVAELNSKLAELKERIESL-ERIRTLLAAIADAEDEIERLREKREAlaELNDERRErlA 630

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1039751015  983 EQRKRK--------------LQAALINRKELLQKVSQLEEELAKVREDSRKEIPFGENERRKLEEDRENRDDPEE 1043
Cdd:PRK02224   631 EKRERKreleaefdearieeAREDKERAEEYLEQVEEKLDELREERDDLQAEIGAVENELEELEELRERREALEN 705
46 PHA02562
endonuclease subunit; Provisional
 2525-2754 1.21e-04

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 47.70  E-value: 1.21e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2525 RRDLNE------VIAIKDSQQKQLLDAQLQQNKELRNECTKLEERLKGLEAEKQSLQMSSDALQKEKQG----LSKEIKN 2594
Cdd:PHA02562   152 RRKLVEdlldisVLSEMDKLNKDKIRELNQQIQTLDMKIDHIQQQIKTYNKNIEEQRKKNGENIARKQNkydeLVEEAKT 231

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2595 LQTQLTALQEEgtLGVYHAQLKAKEEELQRLNMALS--SSQKRTADLEEEL--------VCVQK---------EATRKVS 2655
Cdd:PHA02562   232 IKAEIEELTDE--LLNLVMDIEDPSAALNKLNTAAAkiKSKIEQFQKVIKMyekggvcpTCTQQisegpdritKIKDKLK 309

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2656 EIEDQLKKELKHLHHDAGIMrNETETAEERVAELARDLVEMEQKLLTVTKENKDLMAQIQafgrsmsSLQDSRDHATEEL 2735
Cdd:PHA02562   310 ELQHSLEKLDTAIDELEEIM-DEFNEQSKKLLELKNKISTNKQSLITLVDKAKKVKAAIE-------ELQAEFVDNAEEL 381

                          250
                   ....*....|....*....
gi 1039751015 2736 GDLKKKYDASLKELAQLKE 2754
Cdd:PHA02562   382 AKLQDELDKIVKTKSELVK 400
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 1156-1975 1.29e-04

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 48.12  E-value: 1.29e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1156 LEGRILDLEKDKTQLQKKLQEALIARKAILKKAQE-KEKQLKEELREQKDAYHHLQGQFHEQ---NKEKENIADQLRQLQ 1231
Cdd:TIGR00606  274 LKSRKKQMEKDNSELELKMEKVFQGTDEQLNDLYHnHQRTVREKERELVDCQRELEKLNKERrllNQEKTELLVEQGRLQ 353

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1232 CQARESIDRQLPGTGQQEPGPPAPSLEGISlEDTEPASESDLHAAQPSPPGETAALQATVSVAQIQAQLKEMEVEKEELE 1311
Cdd:TIGR00606  354 LQADRHQEHIRARDSLIQSLATRLELDGFE-RGPFSERQIKNFHTLVIERQEDEAKTAAQLCADLQSKERLKQEQADEIR 432

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1312 LKVSSIASELAKKSEEVLLLQDQINEQGLEIQNLKAASVEA-QAHTELLKQELESSQL--------KVAGLEHLKTLQPE 1382
Cdd:TIGR00606  433 DEKKGLGRTIELKKEILEKKQEELKFVIKELQQLEGSSDRIlELDQELRKAERELSKAeknsltetLKKEVKSLQNEKAD 512

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1383 LDALHKHMGQKEEEVNYLYGQLSEKEqTLTTVQTEMVEQERLIKALHTQLEMQAKEHEERLKQAQVEICELKKKPTELEE 1462
Cdd:TIGR00606  513 LDRKLRKLDQEMEQLNHHTTTRTQME-MLTKDKMDKDEQIRKIKSRHSDELTSLLGYFPNKKQLEDWLHSKSKEINQTRD 591

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1463 ETnakQQLQRKLQAALISRKEALKENKSLQEQLSSARDAVERLTKSlADVESQVSVQNQEKDAVLGKLTILQEERDKLIA 1542
Cdd:TIGR00606  592 RL---AKLNKELASLEQNKNHINNELESKEEQLSSYEDKLFDVCGS-QDEESDLERLKEEIEKSSKQRAMLAGATAVYSQ 667

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1543 EMDRFLLENQSLSGSCESLKLALGGLTEdkekLMEELESVRSSKMAESTEWQEKHKELQKEYEVLLQSYENVSNEAERIQ 1622
Cdd:TIGR00606  668 FITQLTDENQSCCPVCQRVFQTEAELQE----FISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKE 743

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1623 HVVESVRQEKQELYAKLRSTESDKREREKQLQ--DAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEAQPVGGTgE 1700
Cdd:TIGR00606  744 KEIPELRNKLQKVNRDIQRLKNDIEEQETLLGtiMPEEESAKVCLTDVTIMERFQMELKDVERKIAQQAAKLQGSDLD-R 822

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1701 SMEALLSSNSSLKEELEKITLEHKTLSKEFEALMAEKDALSEETRNLKlqVEAQVLKQASLEATEKSDEPKDVIEEVTQA 1780
Cdd:TIGR00606  823 TVQQVNQEKQEKQHELDTVVSKIELNRKLIQDQQEQIQHLKSKTNELK--SEKLQIGTNLQRRQQFEEQLVELSTEVQSL 900

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1781 VVGKSQERDALSDSAKLEDSEAILMGDGAKPGVSETFSSHDDIKNYLQQLDQLKGRIAELEMEKQ--KDRELSQAlENEK 1858
Cdd:TIGR00606  901 IREIKDAKEQDSPLETFLEKDQQEKEELISSKETSNKKAQDKVNDIKEKVKNIHGYMKDIENKIQdgKDDYLKQK-ETEL 979

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1859 NALLTQISAKDSELKLLEEEV--TKRTTLNQQIQEELCRVTKLKETAEEEKDDLEERLMNQLAELNgsignyYQDVTDAQ 1936
Cdd:TIGR00606  980 NTVNAQLEECEKHQEKINEDMrlMRQDIDTQKIQERWLQDNLTLRKRENELKEVEEELKQHLKEMG------QMQVLQMK 1053

                          810       820       830
                   ....*....|....*....|....*....|....*....
gi 1039751015 1937 IKNEQLESEMRNLQRCVSELEEEKQQLVKEKTKVESEIR 1975
Cdd:TIGR00606 1054 QEHQKLEENIDLIKRNHVLALGRQKGYEKEIKHFKKELR 1092
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 1841-2695 1.33e-04

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 47.86  E-value: 1.33e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1841 EMEKQKDRELSQALENEKNAlltqisakDSELKLLEEEVTKRTTLNQQIQEELCRVTKLKETAEEekddLEERLMNQLAE 1920
Cdd:pfam01576    5 EEMQAKEEELQKVKERQQKA--------ESELKELEKKHQQLCEEKNALQEQLQAETELCAEAEE----MRARLAARKQE 72

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1921 LNGSIGNYYQDVTDAQIKNEQLESEMRNLQRCVSELEEE-------KQQLVKEKTKVESEIRKEYMEKIQGAQKGPANKS 1993
Cdd:pfam01576   73 LEEILHELESRLEEEEERSQQLQNEKKKMQQHIQDLEEQldeeeaaRQKLQLEKVTTEAKIKKLEEDILLLEDQNSKLSK 152

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1994 HAKELQEL-------LREKQQEVKQLQKDCIRYLERISALEKTVKALEFVHTESQKDLDVTKGNLAQAVEHRKKAQAELS 2066
Cdd:pfam01576  153 ERKLLEERiseftsnLAEEEEKAKSLSKLKNKHEAMISDLEERLKKEEKGRQELEKAKRKLEGESTDLQEQIAELQAQIA 232

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2067 SFKILLDDTQSEAARVLA---DNLKLKKELQSNKESIKSQIKQKDEDLLRRlEQAEEKHRKEKKNMQEKLDALHREKAHV 2143
Cdd:pfam01576  233 ELRAQLAKKEEELQAALArleEETAQKNNALKKIRELEAQISELQEDLESE-RAARNKAEKQRRDLGEELEALKTELEDT 311

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2144 EETLAEIQVSLTRKDQEMKELQGSLDSTL----AQLAAFTKSMSSLQDDRDRVIDEAKKWERRFGDAIQTKEE------- 2212
Cdd:pfam01576  312 LDTTAAQQELRSKREQEVTELKKALEEETrsheAQLQEMRQKHTQALEELTEQLEQAKRNKANLEKAKQALESenaelqa 391

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2213 EVRLKEENCIALKDQLRQMAIHMEELKITVSRLEHDKEIWE---SKAQTELQHHQKAYD-------KLQEENKELTSQLE 2282
Cdd:pfam01576  392 ELRTLQQAKQDSEHKRKKLEGQLQELQARLSESERQRAELAeklSKLQSELESVSSLLNeaegkniKLSKDVSSLESQLQ 471

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2283 DARQLYHDSKNELTKLESELKSLKDQTTDLNNSLEKCKEHENNLEGIIKQQEADIQNCKFSCEQLETDLAASRELTSRLH 2362
Cdd:pfam01576  472 DTQELLQEETRQKLNLSTRLRQLEDERNSLQEQLEEEEEAKRNVERQLSTLQAQLSDMKKKLEEDAGTLEALEEGKKRLQ 551

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2363 DEINAKEQkiisllsgKEEAIQLAVEELHQQHSKEIKELENLLSQEEEENVALEEENKR--------ALEKT--NQLTEA 2432
Cdd:pfam01576  552 RELEALTQ--------QLEEKAAAYDKLEKTKNRLQQELDDLLVDLDHQRQLVSNLEKKqkkfdqmlAEEKAisARYAEE 623

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2433 LEAIKKESFEQKAQLDSFVKSMSSLQDDRDRIVSDYRQLEERHLSAILEKDQL---IQDAAAENNKLKEEMRGLRSHMDD 2509
Cdd:pfam01576  624 RDRAEAEAREKETRALSLARALEEALEAKEELERTNKQLRAEMEDLVSSKDDVgknVHELERSKRALEQQVEEMKTQLEE 703

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2510 LN-----SENAKLDAEL------VQYRRDLNEVIAIKDSQQKQLLDAQLQQNKELRNECTKLEERL---KGLEAEKQSLQ 2575
Cdd:pfam01576  704 LEdelqaTEDAKLRLEVnmqalkAQFERDLQARDEQGEEKRRQLVKQVRELEAELEDERKQRAQAVaakKKLELDLKELE 783

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2576 MSSDALQKEKQGLSKEIKNLQTQLTALQEEgtlgvyhaqlkAKEEELQRLNMALSS--SQKRTADLEEELVCVQKE---- 2649
Cdd:pfam01576  784 AQIDAANKGREEAVKQLKKLQAQMKDLQRE-----------LEEARASRDEILAQSkeSEKKLKNLEAELLQLQEDlaas 852

                          890       900       910       920
                   ....*....|....*....|....*....|....*....|....*...
gi 1039751015 2650 --ATRKVSEIEDQLKKELKHLHHDAGIMRNETETAEERVAELARDLVE 2695
Cdd:pfam01576  853 erARRQAQQERDELADEIASGASGKSALQDEKRRLEARIAQLEEELEE 900
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 1589-2163 1.43e-04

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 47.66  E-value: 1.43e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1589 ESTEWQEKHKELQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQELYAKLRSTESDKREREKQLQDAEQEMEEMKEKMR 1668
Cdd:TIGR00618  270 EELRAQEAVLEETQERINRARKAAPLAAHIKAVTQIEQQAQRIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQT 349

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1669 KFAKSKQQKI-----LELEEENDRLRAEAQPVGGTGESMEALLSSNSSLKEELEKITLEHKTLSKEFEALMAEKDALSEE 1743
Cdd:TIGR00618  350 LHSQEIHIRDahevaTSIREISCQQHTLTQHIHTLQQQKTTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAHA 429

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1744 TRNLKLQVEAQVLKQASLEATEKSDEPKDV--------IEEVTQAVVGKSQERDALSDSAKLEDSEAILMGDGAKPGVSE 1815
Cdd:TIGR00618  430 KKQQELQQRYAELCAAAITCTAQCEKLEKIhlqesaqsLKEREQQLQTKEQIHLQETRKKAVVLARLLELQEEPCPLCGS 509

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1816 TFSSHDDIKNYLQ------QLDQLKGRIAELEMEKQKDRELSQALENEKNALLTQISAKDSELKLLEEEVTKRTTLNQQI 1889
Cdd:TIGR00618  510 CIHPNPARQDIDNpgpltrRMQRGEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNL 589

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1890 QEELCRVTKLKETAEEEKDDLEERLMNQLAELNGSIGNYYQDVTDAQIKNEQLESEM---RNLQRCVSELEEEKQQLVKE 1966
Cdd:TIGR00618  590 QNITVRLQDLTEKLSEAEDMLACEQHALLRKLQPEQDLQDVRLHLQQCSQELALKLTalhALQLTLTQERVREHALSIRV 669

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1967 KTKVESEIRKEYMEKIQG-AQKGPANKSHAKELQELLREKQQEVKQLQKDCIRYLERISALEKTVKALEFVHTESQKDLD 2045
Cdd:TIGR00618  670 LPKELLASRQLALQKMQSeKEQLTYWKEMLAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKELM 749

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2046 VTKGNLAQAVEHRKKAQAELSSFKILLDDTQSEAARVLADNLKLKKELQSNKESIKSQIKQKDEDLLRRLEQAEEKHRKE 2125
Cdd:TIGR00618  750 HQARTVLKARTEAHFNNNEEVTAALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQCETLVQE 829

                          570       580       590
                   ....*....|....*....|....*....|....*...
gi 1039751015 2126 KKNMQEKLDALHREKAHVEETLAEIQVSLTRKDQEMKE 2163
Cdd:TIGR00618  830 EEQFLSRLEEKSATLGEITHQLLKYEECSKQLAQLTQE 867
PRK11281 PRK11281
mechanosensitive channel MscK;
2268-2631 1.79e-04

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 47.60  E-value: 1.79e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2268 DKLQEENKELTSQLEDARQLYHDSKNELTKLESELKSLKDQTTDlNNSLEKckehennLEGIIKQQEADIQNCKFSCEQL 2347
Cdd:PRK11281    76 DRQKEETEQLKQQLAQAPAKLRQAQAELEALKDDNDEETRETLS-TLSLRQ-------LESRLAQTLDQLQNAQNDLAEY 147

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2348 ETDLAASRELTSRLHDEINA---KEQKIISLLSGKEEAIQLAVEELHQQHSKEIKELENLLSQeeeenvaleeeNKRALE 2424
Cdd:PRK11281   148 NSQLVSLQTQPERAQAALYAnsqRLQQIRNLLKGGKVGGKALRPSQRVLLQAEQALLNAQNDL-----------QRKSLE 216

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2425 KTNQLTEALEAIKKESFEQKAQLDSFVKSMSSLQDDRDRIVSD--YRQLEERHLSAILEKDQLIQDAAAENNKLKEEMRG 2502
Cdd:PRK11281   217 GNTQLQDLLQKQRDYLTARIQRLEHQLQLLQEAINSKRLTLSEktVQEAQSQDEAARIQANPLVAQELEINLQLSQRLLK 296

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2503 LRSHMDDLNSENAK----LDaELVQYRRDLNEVI-AIKDS--------QQKQLLdAQLQQNKELRNECTKLeeRLKGLEA 2569
Cdd:PRK11281   297 ATEKLNTLTQQNLRvknwLD-RLTQSERNIKEQIsVLKGSlllsrilyQQQQAL-PSADLIEGLADRIADL--RLEQFEI 372

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1039751015 2570 EKQSLQMSSDA------LQKEKQGLSKEIKNlqtQLTALqeegtlgvyhaqLKAKEEELQRLNMALSS 2631
Cdd:PRK11281   373 NQQRDALFQPDayidklEAGHKSEVTDEVRD---ALLQL------------LDERRELLDQLNKQLNN 425
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 1359-1643 1.84e-04

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 47.23  E-value: 1.84e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1359 LKQELES--SQLKVAGLEHLKTLQPELDA-----LHKHMGQKEEEVNYLyGQLSEKEQTLTTVQTEMVEQErlikalhtq 1431
Cdd:PRK05771    14 LKSYKDEvlEALHELGVVHIEDLKEELSNerlrkLRSLLTKLSEALDKL-RSYLPKLNPLREEKKKVSVKS--------- 83

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1432 LEMQAKEHEERLKQAQVEICELKKKPTELEEEtnaKQQLQRKLQAALISRK-----EALKENKSLQEQLSSARDAVERLT 1506
Cdd:PRK05771    84 LEELIKDVEEELEKIEKEIKELEEEISELENE---IKELEQEIERLEPWGNfdldlSLLLGFKYVSVFVGTVPEDKLEEL 160

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1507 KSLADVESQVSV-QNQEKDAVLgkLTILQEERDKLIAEMDRFLLENQSLSGScESLKLALGGLTEDKEKLMEELESVRss 1585
Cdd:PRK05771   161 KLESDVENVEYIsTDKGYVYVV--VVVLKELSDEVEEELKKLGFERLELEEE-GTPSELIREIKEELEEIEKERESLL-- 235

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1039751015 1586 kmaestewqEKHKELQKEYE-VLLQSYENVSNEAERiqhvvesvrqekQELYAKLRSTE 1643
Cdd:PRK05771   236 ---------EELKELAKKYLeELLALYEYLEIELER------------AEALSKFLKTD 273
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2515-2745 1.86e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 46.68  E-value: 1.86e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2515 AKLDAELVQYRRDLNEVIAikdsQQKQLLDAQLQQNKELRNECTKLEERLKGLEAEKQSLQMSSDALQKEKQGLSKEIKN 2594
Cdd:COG4942     19 ADAAAEAEAELEQLQQEIA----ELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAE 94

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2595 LQTQLTALQEEGTLGVYHAQLKAKEEELQRLNMALSSSQK-RTADLEEELVCVQKEATRKVSEIEDQLKKELKHLHHDAG 2673
Cdd:COG4942     95 LRAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAvRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERA 174

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1039751015 2674 IMRNETETAEERVAELARDLVEMEQKLLTVTKENKDLMAQIQAFGRSMSSLQDSRDHATEELGDLKKKYDAS 2745
Cdd:COG4942    175 ELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAA 246
PRK11281 PRK11281
mechanosensitive channel MscK;
1377-1554 1.87e-04

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 47.60  E-value: 1.87e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1377 KTLQPELDALHKHmGQKEEEVNYLYGQLsekEQTLTTV-QTEMVEQErlikalHTQLEMQAKEHEERLKQAQVEICELKK 1455
Cdd:PRK11281    39 ADVQAQLDALNKQ-KLLEAEDKLVQQDL---EQTLALLdKIDRQKEE------TEQLKQQLAQAPAKLRQAQAELEALKD 108

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1456 KPTELEEETNAKQ---QLQRKLQAALISRKEALKENKSLQEQLSSARDAVERLTKSLAdvESQVSVQ---NQEKDAVLGK 1529
Cdd:PRK11281   109 DNDEETRETLSTLslrQLESRLAQTLDQLQNAQNDLAEYNSQLVSLQTQPERAQAALY--ANSQRLQqirNLLKGGKVGG 186

                          170       180       190
                   ....*....|....*....|....*....|....
gi 1039751015 1530 LTILQEERDKLIAEMD---------RFLLENQSL 1554
Cdd:PRK11281   187 KALRPSQRVLLQAEQAllnaqndlqRKSLEGNTQ 220
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
725-1116 1.88e-04

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 47.34  E-value: 1.88e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  725 LSEEVKESAEEARSTLAAVTEERDQLLYQVKELDVLAELRARVQELESSLAEAEKQRGLDYESQRAQHNLLTEQIHSLSI 804
Cdd:PRK02224   277 LAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLEE 356

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  805 EAKSKDVKIEALQRELDGVQLQFCEQGTQMKTLQSQLEAKEREVREGTERLRDISQEMEGLSQALSQKELEIAKMDQLLL 884
Cdd:PRK02224   357 RAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAELEATLR 436

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  885 EKQKDVETLQQ---------------------TIQEKDQQVTELSFSMTEKMVQLN--EEKFSLGVEIKTLKEQLNLLSR 941
Cdd:PRK02224   437 TARERVEEAEAlleagkcpecgqpvegsphveTIEEDRERVEELEAELEDLEEEVEevEERLERAEDLVEAEDRIERLEE 516

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  942 TEEATKEQVEESGAGsslkLGHDESGQEGLQQELELLRKESEQRKRKLQAALINRKELLQKVSQLEEELAKVRE------ 1015
Cdd:PRK02224   517 RREDLEELIAERRET----IEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKEriesle 592

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1016 DSRKEIPFGENERRKLEEDRENRDDPEEWGTSKwREVEASLKQTISEKEVELEGirrdlkektAAEEELQAVVQRMTRDL 1095
Cdd:PRK02224   593 RIRTLLAAIADAEDEIERLREKREALAELNDER-RERLAEKRERKRELEAEFDE---------ARIEEAREDKERAEEYL 662

                          410       420
                   ....*....|....*....|.
gi 1039751015 1096 QSKTKQIDLLQEEVTENQATI 1116
Cdd:PRK02224   663 EQVEEKLDELREERDDLQAEI 683
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 196-1013 1.95e-04

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 47.27  E-value: 1.95e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  196 QEKEELISTLQTQLSQTQAEQAAQLSSMQQVVREKDARFETQVRLHEDELLQLVTQSDVETEMQQKLRVMQRKLEEHEEA 275
Cdd:pfam02463  173 EALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEE 252

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  276 LL-------GRAQVVDLLQKELTSAEQRNQVLSQQLQLLEAEHNTLKNTMETERQESKTLMEKV---ELEVAERKLSFHN 345
Cdd:pfam02463  253 IEsskqeieKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLkesEKEKKKAEKELKK 332

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  346 LQEEMHQLQGQLERAGQAQADLETQYSALQQRHKTEMEEKTACILSLQKNEQELQSACAALKEENSKLLQEKHDQAAESA 425
Cdd:pfam02463  333 EKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLE 412

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  426 QAMRQLEDQLQQKSKEISQ------FVNKPNLQKNETASQTSLPDVNNEGDQAVMEETVASLQKRVVELENEKGALLLSS 499
Cdd:pfam02463  413 LARQLEDLLKEEKKEELEIleeeeeSIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSR 492

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  500 GELEELKAENEKLSSRITLLEAQNRAGEADG-------------------------TVCEVSTAGTTLLNRSDSSPEENG 554
Cdd:pfam02463  493 QKLEERSQKESKARSGLKVLLALIKDGVGGRiisahgrlgdlgvavenykvaistaVIVEVSATADEVEERQKLVRALTE 572

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  555 QAVLENTFSQKHKELSVLLVEMKEAQEEIAFLKSQLQGKRPEGDYEVLDRREVQLMESEGPPSVTAGDVLCAPSDESSGP 634
Cdd:pfam02463  573 LPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGV 652

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  635 AAEEEQAGMKDRHRASEAGPLNDAGMELSSPKLDGVDKSLAVSHVCQCHQGELERLKTQVLELETSLHTAEETYKRNLSE 714
Cdd:pfam02463  653 SLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQD 732

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  715 KVKEISSLtQLSEEVKESAEEARSTLAAVTEERDQLLYQVKELDVLAELRARVQELESSLAEAEKQRGLDYESQRAQHNL 794
Cdd:pfam02463  733 KINEELKL-LKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELK 811

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  795 LTEQIHSLSIEAKSKDVKIEALQRELDGVQLQFCEQGTQMKTLQSQLEAKEREVREGTERLRDISQEMEglsqalsqkEL 874
Cdd:pfam02463  812 EEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELE---------EQ 882

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  875 EIAKMDQLLLEKQKDVETLQQTIQEKDQQVTELSFSMTEKMVQLNEEKFSLGVEIKTLKEQLNLLSRTEEATKEQVEESG 954
Cdd:pfam02463  883 KLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERN 962

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1039751015  955 AGSSLKLGHDESGQEGLQQELELLRKESEQRKRKLQAALINRKELLQKVSQLEEELAKV 1013
Cdd:pfam02463  963 KRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQRLKE 1021
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2539-2758 2.03e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 46.68  E-value: 2.03e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2539 QKQLLDAQLQQNKELRNECTKLEERLKGLEAEKQSLQMSSDALQKEKQGLSKEIKNLQTQLTALQEEgtlgvyHAQLKAK 2618
Cdd:COG4942     18 QADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAE------LAELEKE 91

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2619 EEELQRlnmalsSSQKRTADLEEELVCVQKeaTRKVSEIEDQLK-KELKHLHHDAGIMRNETETAEERVAELARDLVEME 2697
Cdd:COG4942     92 IAELRA------ELEAQKEELAELLRALYR--LGRQPPLALLLSpEDFLDAVRRLQYLKYLAPARREQAEELRADLAELA 163

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1039751015 2698 QKLLTVTKENKDLMAQIQAFGRSMSSLQDSRDHATEELGDLKKKYDASLKELAQLKEWQDS 2758
Cdd:COG4942    164 ALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEE 224
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
812-1027 2.09e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 47.22  E-value: 2.09e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  812 KIEALQRELDGVQLQFCEQGTQMKTLQSQLEA--KEREVREGTERLRDISQEMEGLSQALSQKELEIAKmdqlLLEKQKD 889
Cdd:COG4913    611 KLAALEAELAELEEELAEAEERLEALEAELDAlqERREALQRLAEYSWDEIDVASAEREIAELEAELER----LDASSDD 686

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  890 VETLQQTIQEKDQQVTElsfsmtekmvqLNEEKFSLGVEIKTLKEQLNLLSRTEEATKEQVEESGAGsslklghdesGQE 969
Cdd:COG4913    687 LAALEEQLEELEAELEE-----------LEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDL----------ARL 745

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1039751015  970 GLQQELELLRKESEQRK--RKLQAALINRKELLQ-KVSQLEEELAKVREDSRKEIPFGENE 1027
Cdd:COG4913    746 ELRALLEERFAAALGDAveRELRENLEERIDALRaRLNRAEEELERAMRAFNREWPAETAD 806
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1307-1751 2.10e-04

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 47.32  E-value: 2.10e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1307 KEELELKVSSIASELAKKSEEVLLLQDQINEQGLEIQNLKAASVEAQAHTELLKQELESSQLKVAGLE-HLKTLQPELDA 1385
Cdd:TIGR04523  220 ISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEkQLNQLKSEISD 299

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1386 LHKhmgQKEEEVN-YLYGQLSEKEQTLTTVQTEMVEQERLIKALHTQLEMQAKEHEERLKQAQVEICELKKKPTELEEET 1464
Cdd:TIGR04523  300 LNN---QKEQDWNkELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLK 376

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1465 NAKQQLQRKLQaALISRKEAL--------KENKSLQEQLSSARDAVERLTKSLADVESQVSVQNQEKDAVLGKLTILQEE 1536
Cdd:TIGR04523  377 KENQSYKQEIK-NLESQINDLeskiqnqeKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELI 455

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1537 RDKLIAEMDRFLLENQSLSGSCESLKLALggltEDKEKLMEELESVRSSKMAESTEWQEKHKELQKEYEVLLQSYENVSN 1616
Cdd:TIGR04523  456 IKNLDNTRESLETQLKVLSRSINKIKQNL----EQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLES 531

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1617 EAERIQHVVESVRQEKQELYAKLRSTESDKREREKQLQDAEQEMEEMKEKMRKfaKSKQQKILELEEENDRLRAEaqpvg 1696
Cdd:TIGR04523  532 EKKEKESKISDLEDELNKDDFELKKENLEKEIDEKNKEIEELKQTQKSLKKKQ--EEKQELIDQKEKEKKDLIKE----- 604

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1039751015 1697 gtgesMEALLSSNSSLKEELEKITLEHKTLSKEFEALMAEKDALSEETRNLKLQV 1751
Cdd:TIGR04523  605 -----IEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETI 654
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 807-1088 2.18e-04

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 46.84  E-value: 2.18e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  807 KSKDVKIEALQrELDGVQLQFCEQGTQMKTLqSQLEAKEREVREGTERLRDISQEmEGLSQALsQKELEIAKMDQLLLEK 886
Cdd:PRK05771    16 SYKDEVLEALH-ELGVVHIEDLKEELSNERL-RKLRSLLTKLSEALDKLRSYLPK-LNPLREE-KKKVSVKSLEELIKDV 91

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  887 QKDVETLQQTIQEKDQQVTELsfsmTEKMVQLNEEKF------SLGVEIKTLKEQLNLLSRTEEATKEQVEESGAgsslk 960
Cdd:PRK05771    92 EEELEKIEKEIKELEEEISEL----ENEIKELEQEIErlepwgNFDLDLSLLLGFKYVSVFVGTVPEDKLEELKL----- 162

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  961 lghdESGQEGLqqelellrKESEQRKRKLQAALINRKELLQKVsqlEEELAKVrEDSRKEIPfgenerrkleedrenrdd 1040
Cdd:PRK05771   163 ----ESDVENV--------EYISTDKGYVYVVVVVLKELSDEV---EEELKKL-GFERLELE------------------ 208

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*...
gi 1039751015 1041 peEWGTSKwrEVEASLKQTISEKEVELEGIRRDLKEKTAAEEELQAVV 1088
Cdd:PRK05771   209 --EEGTPS--ELIREIKEELEEIEKERESLLEELKELAKKYLEELLAL 252
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
687-869 2.29e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 47.22  E-value: 2.29e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  687 LERLKTQVLELETSLHTAEETYK------RNLSEKVKEISSLTQLSEEVKESAEeARSTLAAVTEERDQLLyqvKELDVL 760
Cdd:COG4913    612 LAALEAELAELEEELAEAEERLEaleaelDALQERREALQRLAEYSWDEIDVAS-AEREIAELEAELERLD---ASSDDL 687

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  761 AELRARVQELESSLAEAEKQRgldyESQRAQHNLLTEQIHSLSIEAKSKDVKIEALQRELDGVQLQFCEQgtqmKTLQSQ 840
Cdd:COG4913    688 AALEEQLEELEAELEELEEEL----DELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEE----RFAAAL 759

                          170       180       190
                   ....*....|....*....|....*....|
gi 1039751015  841 LEAKEREVREG-TERLRDISQEMEGLSQAL 869
Cdd:COG4913    760 GDAVERELRENlEERIDALRARLNRAEEEL 789
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1285-1510 2.46e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 46.30  E-value: 2.46e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1285 AALQATVSVAQIQAQLKEMEVEKEELELKVSSIASELAKKSEEVLLLQDQINEQGLEIQNLKAASVEAQAHTELLKQELE 1364
Cdd:COG4942     14 AAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIA 93

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1365 SSQLKVAGLEHLktLQPELDALHKHMGQKEEEV---NYLYGQLSEKEQTLTTVQTEMVEQERLIKALHTQLEMQAKEHEE 1441
Cdd:COG4942     94 ELRAELEAQKEE--LAELLRALYRLGRQPPLALllsPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEA 171

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1039751015 1442 RLKQAQVEICELKKKPTELEEETNAKQQLQRKLQAALISRKEALKENKSLQEQLSSARDAVERLTKSLA 1510
Cdd:COG4942    172 ERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAA 240
PRK01156 PRK01156
chromosome segregation protein; Provisional
 1491-2043 2.62e-04

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 46.82  E-value: 2.62e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1491 LQEQLSSARDAVERLTKSLADVESQVSVQNQEKDAVLGKLTILQEERDKLIAEMDRFLLENQSLSGSCESLKLALGGLTE 1570
Cdd:PRK01156   188 LEEKLKSSNLELENIKKQIADDEKSHSITLKEIERLSIEYNNAMDDYNNLKSALNELSSLEDMKNRYESEIKTAESDLSM 267

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1571 DKEK------LMEELESVRSSKMAESTEWQEKHKELQKEYEVLLQSYENVSNEAERIQHVVESVrQEKQELYAKLRSTES 1644
Cdd:PRK01156   268 ELEKnnyykeLEERHMKIINDPVYKNRNYINDYFKYKNDIENKKQILSNIDAEINKYHAIIKKL-SVLQKDYNDYIKKKS 346

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1645 DKREREKQLQDAEQEMEEMKEKMRKFaKSKQQKILELEEENDRLRAEAQPVGGTGE-SMEALLSSNSSLKEELEKITLEH 1723
Cdd:PRK01156   347 RYDDLNNQILELEGYEMDYNSYLKSI-ESLKKKIEEYSKNIERMSAFISEILKIQEiDPDAIKKELNEINVKLQDISSKV 425

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1724 KTLSKEFEALMAEKDALSEETRNLKLQVEAQVLkqASLEATEKSdepKDVIEEVTQAVVGKSQERDALSDSAKLEDSEAI 1803
Cdd:PRK01156   426 SSLNQRIRALRENLDELSRNMEMLNGQSVCPVC--GTTLGEEKS---NHIINHYNEKKSRLEEKIREIEIEVKDIDEKIV 500

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1804 LMGDgakpgvSETFSSHDDIKNYLQQLDQLKGRIAELEMEKQKDRELSQAlENEKNALLTQISAKDseLKLLEEEVTKRT 1883
Cdd:PRK01156   501 DLKK------RKEYLESEEINKSINEYNKIESARADLEDIKIKINELKDK-HDKYEEIKNRYKSLK--LEDLDSKRTSWL 571

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1884 TLNQQIQE-ELCRVTKLKETAEEEKDDLEERLM--------------NQLAELNGSIGNY---YQDVTDAQIKNEQLESE 1945
Cdd:PRK01156   572 NALAVISLiDIETNRSRSNEIKKQLNDLESRLQeieigfpddksyidKSIREIENEANNLnnkYNEIQENKILIEKLRGK 651

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1946 MRNLQRCVSELEEEKQQLvKEKTKVESEIRKEYMEKIQGAQKGPANKSHAKELQELLREKQQEVKQLQKDCIRYLERISA 2025
Cdd:PRK01156   652 IDNYKKQIAEIDSIIPDL-KEITSRINDIEDNLKKSRKALDDAKANRARLESTIEILRTRINELSDRINDINETLESMKK 730

                          570
                   ....*....|....*...
gi 1039751015 2026 LEKTVKALEFVHTESQKD 2043
Cdd:PRK01156   731 IKKAIGDLKRLREAFDKS 748
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 1420-1692 2.69e-04

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 46.84  E-value: 2.69e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1420 EQERLIKALHtqlEMQAkeheerlkqaqVEICELKKKptELEEETNAKQQLQRKLQAALISRKEALKENKSLQEQLSSAR 1499
Cdd:PRK05771    17 YKDEVLEALH---ELGV-----------VHIEDLKEE--LSNERLRKLRSLLTKLSEALDKLRSYLPKLNPLREEKKKVS 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1500 -----DAVERLTKSLADVESQVSVQNQEkdavlgkLTILQEERDKLIAEMDR------FLLENQSLSGScESLKLALGGL 1568
Cdd:PRK05771    81 vksleELIKDVEEELEKIEKEIKELEEE-------ISELENEIKELEQEIERlepwgnFDLDLSLLLGF-KYVSVFVGTV 152

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1569 TEDKEKLMEELESVRSSKMAESTEwqEK-------HKELQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQELyaklrs 1641
Cdd:PRK05771   153 PEDKLEELKLESDVENVEYISTDK--GYvyvvvvvLKELSDEVEEELKKLGFERLELEEEGTPSELIREIKEEL------ 224

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1039751015 1642 tesdkREREKQLQDAEqemeemkEKMRKFAKSKQQKILELEE--ENDRLRAEA 1692
Cdd:PRK05771   225 -----EEIEKERESLL-------EELKELAKKYLEELLALYEylEIELERAEA 265
46 PHA02562
endonuclease subunit; Provisional
 2247-2467 3.35e-04

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 46.16  E-value: 3.35e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2247 HDKEIWESKAQT--ELQHHQKAYDKLQEENKELTSQLEDArqlyhdsKNELTKLESELKSLKDQTTDLNNSLEKCKEHEN 2324
Cdd:PHA02562   200 YNKNIEEQRKKNgeNIARKQNKYDELVEEAKTIKAEIEEL-------TDELLNLVMDIEDPSAALNKLNTAAAKIKSKIE 272

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2325 NLEGIIKQQEaDIQNCKfSCEQletDLAASRELTSRLHDEINAKEQKIISLLSGKEEAIQLAVEELHQQhsKEIKELENL 2404
Cdd:PHA02562   273 QFQKVIKMYE-KGGVCP-TCTQ---QISEGPDRITKIKDKLKELQHSLEKLDTAIDELEEIMDEFNEQS--KKLLELKNK 345

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1039751015 2405 LSQEEEENVALEEENKRALEKTNQLTEALEAIKKESFEQKAQLDSFVKSMSSLQDDRDR--IVSD 2467
Cdd:PHA02562   346 ISTNKQSLITLVDKAKKVKAAIEELQAEFVDNAEELAKLQDELDKIVKTKSELVKEKYHrgIVTD 410
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2655-2878 3.57e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.91  E-value: 3.57e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2655 SEIEDQLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLTVTKENKDLMAQIQAFGRSMSSLQDSRDHATEE 2734
Cdd:COG4942     19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE 98

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2735 LGDLKKKYDASLKELAQLkewQDSSREGDVLSQAAFplSTSENVLSRLEKLNQQLTSKDEQLLHLSSELESSHNQVQSIS 2814
Cdd:COG4942     99 LEAQKEELAELLRALYRL---GRQPPLALLLSPEDF--LDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAER 173

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1039751015 2815 KAMTSLQNERDRLWSELEKFRKSEEGKQRAAAPSAASSPAEVQSLKKAMSSLQNDRDRLLKELK 2878
Cdd:COG4942    174 AELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAA 237
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1318-1487 3.67e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 46.45  E-value: 3.67e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1318 ASELAKKSEEVLLLQDQINEQGLEIQNLKAASVEAQAHTELLKQELES--SQLKVAGLEHLKTLQPELDALHKHMGQKEE 1395
Cdd:COG4913    280 ALRLWFAQRRLELLEAELEELRAELARLEAELERLEARLDALREELDEleAQIRGNGGDRLEQLEREIERLERELEERER 359

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1396 EVNYLYGQLSEKEQTLTTVQTEMVEQERLIKALHTQLEMQAKEHEERLKQAQVEICELKKKPTELEEETNAKQQLQRKLQ 1475
Cdd:COG4913    360 RRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIP 439

                          170
                   ....*....|..
gi 1039751015 1476 AALISRKEALKE 1487
Cdd:COG4913    440 ARLLALRDALAE 451
PTZ00121 PTZ00121
MAEBL; Provisional
 688-1202 3.94e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 46.67  E-value: 3.94e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  688 ERLKTQVLELETSLHTAEETYKrnlSEKVKEISSLTQLSEEVKEsAEEARSTLAAVTEERDQLLYQVKELDVLAELRARV 767
Cdd:PTZ00121  1276 EARKADELKKAEEKKKADEAKK---AEEKKKADEAKKKAEEAKK-ADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAE 1351

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  768 QELESSLAEAEKQRGLDYESQRAQHNLLTEQIHSLSIEAKSKD---VKIEALQRELDGVQlqfceQGTQMKTLQSQLEAK 844
Cdd:PTZ00121  1352 AEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADeakKKAEEDKKKADELK-----KAAAAKKKADEAKKK 1426

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  845 EREVREGTERLRDISQEMEGLSQALSQKELEIAKMDQLLLEKQKDVETLQQTIQEKdQQVTELSFSMTEKMVQLNEEKfs 924
Cdd:PTZ00121  1427 AEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEA-KKADEAKKKAEEAKKKADEAK-- 1503

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  925 lgvEIKTLKEQLNLLSRTEEATK----EQVEESGAGSSLKLGHDESGQEGLQQELEL-----------LRKESEQRKRKL 989
Cdd:PTZ00121  1504 ---KAAEAKKKADEAKKAEEAKKadeaKKAEEAKKADEAKKAEEKKKADELKKAEELkkaeekkkaeeAKKAEEDKNMAL 1580

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  990 QAALINRKELLQKVSQLEEELAKVREDSRKEIPFGENERRKLEEDRENRDDPEEWGTSKWREVEASLKQTISEKEVELEG 1069
Cdd:PTZ00121  1581 RKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENK 1660

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1070 IRRDLKEKTAAEEELQA-VVQRMTRDLQSKTKQIDLLQEEVTENQATIQKLVTGTMDAGNGGSAAPVKETAASSPPGAGG 1148
Cdd:PTZ00121  1661 IKAAEEAKKAEEDKKKAeEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAE 1740

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1039751015 1149 EEHWKPElEGRILDLEKDKTQLQKKLQEaliarKAILKKAQEKEKQLKEELREQ 1202
Cdd:PTZ00121  1741 EDKKKAE-EAKKDEEEKKKIAHLKKEEE-----KKAEEIRKEKEAVIEEELDEE 1788
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 153-442 4.53e-04

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 46.21  E-value: 4.53e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  153 HELQEKEKLISSLQAQLDQSEQA-----SQLDKSSAEMEDFVLMKQQLQEKE----ELISTLQTQLSQTQAEQAAQLSSM 223
Cdd:TIGR02169  681 ERLEGLKRELSSLQSELRRIENRldelsQELSDASRKIGEIEKEIEQLEQEEeklkERLEELEEDLSSLEQEIENVKSEL 760

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  224 QQVVREKDARFETQVRLHE-------DELLQLVTQSDVETEMQQKLRVMQRK-LEEHEEALLGRAQVVDLLQKELTSAEQ 295
Cdd:TIGR02169  761 KELEARIEELEEDLHKLEEalndleaRLSHSRIPEIQAELSKLEEEVSRIEArLREIEQKLNRLTLEKEYLEKEIQELQE 840

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  296 RNQVLSQQLQLLEAEHNTLKNTMETERQESKTL----------MEKVELEVAERKLSFHNLQEEMHQLQGQLERAGQAQA 365
Cdd:TIGR02169  841 QRIDLKEQIKSIEKEIENLNGKKEELEEELEELeaalrdlesrLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLS 920

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  366 DLETQYSALQQRHKT------EMEEKTACILSL---QKNEQELQSACAALKEENSKL-------------LQEKHDQAAE 423
Cdd:TIGR02169  921 ELKAKLEALEEELSEiedpkgEDEEIPEEELSLedvQAELQRVEEEIRALEPVNMLAiqeyeevlkrldeLKEKRAKLEE 1000

                          330
                   ....*....|....*....
gi 1039751015  424 SAQAMRQLEDQLQQKSKEI 442
Cdd:TIGR02169 1001 ERKAILERIEEYEKKKREV 1019
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1710-1921 4.79e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.53  E-value: 4.79e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1710 SSLKEELEKITLEHKTLSKEFEALMAEKDALSEETRNLKLQVEA--QVLKQASLEATEKSDEPKDVIEEVTQAVVGKSQE 1787
Cdd:COG4942     23 AEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAAlaRRIRALEQELAALEAELAELEKEIAELRAELEAQ 102

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1788 RDALSDSAKledsEAILMGDGAKPGV---SETFSSHDDIKNYLQQL-DQLKGRIAELEMEKQKDRELSQALENEKNALLT 1863
Cdd:COG4942    103 KEELAELLR----ALYRLGRQPPLALllsPEDFLDAVRRLQYLKYLaPARREQAEELRADLAELAALRAELEAERAELEA 178

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1039751015 1864 QISAKDSELKLLEEEVTKRTTLNQQIQEELcrvtKLKETAEEEKDDLEERLMNQLAEL 1921
Cdd:COG4942    179 LLAELEEERAALEALKAERQKLLARLEKEL----AELAAELAELQQEAEELEALIARL 232
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
2347-2827 5.23e-04

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 45.80  E-value: 5.23e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2347 LETDLAASRELTSRLHDE-INAKEQKiisllsgkeEAIQLAVEElHQQHSKEIKELENLLSQEEEENVALEEENKRALEK 2425
Cdd:PRK02224   211 LESELAELDEEIERYEEQrEQARETR---------DEADEVLEE-HEERREELETLEAEIEDLRETIAETEREREELAEE 280

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2426 TNQLTEALEAIKKESFEQKAQLDSFVKSMSSLQDDRDRIVSDYRQLEERhlsaILEKDQLIQDAAAENNKLKEEMRGLRS 2505
Cdd:PRK02224   281 VRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDR----LEECRVAAQAHNEEAESLREDADDLEE 356

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2506 HMDDLNSENAKLDAELVQYRRDLNEviaikdsqqkqlldaQLQQNKELRNECTKLEERLKGLEAEKQSLQMSSDALQKEK 2585
Cdd:PRK02224   357 RAEELREEAAELESELEEAREAVED---------------RREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREER 421

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2586 QGLSKEIKNLQTQLT----------ALQEEG--------------------------TLGVYHAQLKAKEEEL-QRLNMA 2628
Cdd:PRK02224   422 DELREREAELEATLRtarerveeaeALLEAGkcpecgqpvegsphvetieedrerveELEAELEDLEEEVEEVeERLERA 501

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2629 --LSSSQKRTADLEE------ELVCVQKEATRKVSEIEDQLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKL 2700
Cdd:PRK02224   502 edLVEAEDRIERLEErredleELIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKL 581

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2701 LTVTKEN------KDLMAQIQAFGRSMSSLQDSRDHATeELGDLKKKYdasLKELAQLKEWQDSSREGDVLSQAAFPLST 2774
Cdd:PRK02224   582 AELKERIesleriRTLLAAIADAEDEIERLREKREALA-ELNDERRER---LAEKRERKRELEAEFDEARIEEAREDKER 657

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1039751015 2775 SENVLSRLEKLNQQLTSKDEQLLHLSSELESSHNQVQSISKAMTSLQNERDRL 2827
Cdd:PRK02224   658 AEEYLEQVEEKLDELREERDDLQAEIGAVENELEELEELRERREALENRVEAL 710
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 2051-2604 5.26e-04

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 45.98  E-value: 5.26e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2051 LAQAVEHRKKAQAELSSFKILLDDTQSEAARVLADNLKLKKELQSNKESIKSQIKQKDEDLLRRLEQAEEKHRKEKKNMq 2130
Cdd:pfam12128  246 LQQEFNTLESAELRLSHLHFGYKSDETLIASRQEERQETSAELNQLLRTLDDQWKEKRDELNGELSAADAAVAKDRSEL- 324

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2131 EKLDALHR-------EKAHVE-ETLAEIQVSLTRKDQEMKELQGSLDSTLAQLAAFTKSMSS--------LQDDRDRVID 2194
Cdd:pfam12128  325 EALEDQHGafldadiETAAADqEQLPSWQSELENLEERLKALTGKHQDVTAKYNRRRSKIKEqnnrdiagIKDKLAKIRE 404

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2195 EAKKWERRFGDAIQTKEEEVRLKEENCIA-LKDQLRQMAIHMEELKITV------SRLEHDKEIWES---KAQTELQHHQ 2264
Cdd:pfam12128  405 ARDRQLAVAEDDLQALESELREQLEAGKLeFNEEEYRLKSRLGELKLRLnqatatPELLLQLENFDErieRAREEQEAAN 484

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2265 KAYDKLQEENKELTSQLEDARQLYHDSKNELTKLESELKSLKDQ---------------------------------TTD 2311
Cdd:pfam12128  485 AEVERLQSELRQARKRRDQASEALRQASRRLEERQSALDELELQlfpqagtllhflrkeapdweqsigkvispellhRTD 564

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2312 LNNSL-EKCKEHENNLEGI-IKQQEADIQNCKFSCEQLETDLAASRELTSRLHDEINAKEQKiISLLSGKEEAIQLAVEE 2389
Cdd:pfam12128  565 LDPEVwDGSVGGELNLYGVkLDLKRIDVPEWAASEEELRERLDKAEEALQSAREKQAAAEEQ-LVQANGELEKASREETF 643

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2390 LHQQHSKEIKELENLLSQEEEENVALEEENKRALEKTNQLTEALEAikkesfeQKAQLDSFVKSMSSLQDDRDRIVSDYR 2469
Cdd:pfam12128  644 ARTALKNARLDLRRLFDEKQSEKDKKNKALAERKDSANERLNSLEA-------QLKQLDKKHQAWLEEQKEQKREARTEK 716

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2470 QLEERHLSAILEK--DQLIQDAAAENNKLKEEMRGLRSHMD--------------DLNSENAKLDAELVQYRRDLNEVIA 2533
Cdd:pfam12128  717 QAYWQVVEGALDAqlALLKAAIAARRSGAKAELKALETWYKrdlaslgvdpdviaKLKREIRTLERKIERIAVRRQEVLR 796

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1039751015 2534 IKDSQQKQLL---DAQLQQNKELRNECTKLEERLKGLEAE----KQSLQMSSDALQKEKQGLSKEIKNLQTQLTALQE 2604
Cdd:pfam12128  797 YFDWYQETWLqrrPRLATQLSNIERAISELQQQLARLIADtklrRAKLEMERKASEKQQVRLSENLRGLRCEMSKLAT 874
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1388-1925 5.37e-04

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 45.83  E-value: 5.37e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1388 KHMGQKEEEVNYLYGQLSEKEQTLTTVQTEMVEQERL------IKALHTQLEMQAKEHEERLKQAQVEICELKKKPTELE 1461
Cdd:PRK03918   200 KELEEVLREINEISSELPELREELEKLEKEVKELEELkeeieeLEKELESLEGSKRKLEEKIRELEERIEELKKEIEELE 279

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1462 E------ETNAKQQLQRKLQAALISRKEALKENKSLQEQLSSARDAVERLTKSLADVESQVSVQNQEKDAVLGKLTILqE 1535
Cdd:PRK03918   280 EkvkelkELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEEL-E 358

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1536 ERDKLIAEMDRFLLENQSLSG-----SCESLKLALGGLTEDKEKLMEELESVRsskmAESTEWQEKHKELQKEYEVL--- 1607
Cdd:PRK03918   359 ERHELYEEAKAKKEELERLKKrltglTPEKLEKELEELEKAKEEIEEEISKIT----ARIGELKKEIKELKKAIEELkka 434

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1608 ---------LQSYENVSNEAERIQHVVESVRQEKQELYAKLRSTESDKREREKQLQDAEQEMEEMKEKMRKFAKSKQQKI 1678
Cdd:PRK03918   435 kgkcpvcgrELTEEHRKELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKLKELAEQLKELEEKLKK 514

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1679 LELEEendrLRAEAQPVGGTGESMEALLSSNSSLKEELEKItlehKTLSKEFEALMAEKDALSEETRNLKLQVEAQVLKQ 1758
Cdd:PRK03918   515 YNLEE----LEKKAEEYEKLKEKLIKLKGEIKSLKKELEKL----EELKKKLAELEKKLDELEEELAELLKELEELGFES 586

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1759 ASlEATEKSDEPKDVIEEVTQAVVGKSQERDALSDSAKLEDSEailmgDGAKPGVSETFSSHDDIKNYLQQLDQL--KGR 1836
Cdd:PRK03918   587 VE-ELEERLKELEPFYNEYLELKDAEKELEREEKELKKLEEEL-----DKAFEELAETEKRLEELRKELEELEKKysEEE 660

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1837 IAELEMEKQKDRELSQALENEKNALLTQISAKDSELKLLEEEVTKRTTLNQQIQ---EELCRVTKLKETAEEEKDDLEER 1913
Cdd:PRK03918   661 YEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKAKKELEkleKALERVEELREKVKKYKALLKER 740

                          570
                   ....*....|..
gi 1039751015 1914 LMNQLAELNGSI 1925
Cdd:PRK03918   741 ALSKVGEIASEI 752
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1372-2185 5.46e-04

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 45.88  E-value: 5.46e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1372 GLEHLKTLQPELDALHKHMGQKEEEVNYLY-GQLSEKEQTLTTVQTEMVEQERLIKALHTQLEMQAKEHEERLKQAQVEI 1450
Cdd:pfam15921   72 GKEHIERVLEEYSHQVKDLQRRLNESNELHeKQKFYLRQSVIDLQTKLQEMQMERDAMADIRRRESQSQEDLRNQLQNTV 151

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1451 CELKKKPTELEEETNAKQQLQRKLQAALISRKEALKENKSLQEQLSSARDaverltKSLADVESQVSVQNQEKDAVLGKl 1530
Cdd:pfam15921  152 HELEAAKCLKEDMLEDSNTQIEQLRKMMLSHEGVLQEIRSILVDFEEASG------KKIYEHDSMSTMHFRSLGSAISK- 224

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1531 tILQEERDKLIAEMDR-FLLENQSLSGSCES---LKLALGGLTEDKEKLMEELESVRSSKMAESTEWQEKHKELQKEYEV 1606
Cdd:pfam15921  225 -ILRELDTEISYLKGRiFPVEDQLEALKSESqnkIELLLQQHQDRIEQLISEHEVEITGLTEKASSARSQANSIQSQLEI 303

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1607 LLQSYENVSNEAERIQHVVES-VRQEKQELYAKLRSTESDKREREKQLQDAEQEMEEMKEKMRKFAKS------------ 1673
Cdd:pfam15921  304 IQEQARNQNSMYMRQLSDLEStVSQLRSELREAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQEsgnlddqlqkll 383

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1674 ----KQQKILELEEENDRLRAEAQpvggTGESMeallsSNSSLKEELEKITLEHKTLSKEFEALMAEKDALSEETRNLKL 1749
Cdd:pfam15921  384 adlhKREKELSLEKEQNKRLWDRD----TGNSI-----TIDHLRRELDDRNMEVQRLEALLKAMKSECQGQMERQMAAIQ 454

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1750 QVEAQVLKQASLEATEKSDEP--KDVIEEVT-QAVVGKSQERDALSDSAKLEDSEAILMGDGAKpgvSETFSSHDDIKny 1826
Cdd:pfam15921  455 GKNESLEKVSSLTAQLESTKEmlRKVVEELTaKKMTLESSERTVSDLTASLQEKERAIEATNAE---ITKLRSRVDLK-- 529

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1827 LQQLDQLKGRIAELemekqkdrelsQALENEKNALLTQISAKDSELKLLEEEVTKRTTLNQQiqeelcrVTKLKETAEEE 1906
Cdd:pfam15921  530 LQELQHLKNEGDHL-----------RNVQTECEALKLQMAEKDKVIEILRQQIENMTQLVGQ-------HGRTAGAMQVE 591

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1907 KDDLEERLMNQLAELNgsignyyqdvtDAQIKNEQLESEMRNLQRCVSELEEEKQQLV---KEKTKVESEIRKEYMEKIQ 1983
Cdd:pfam15921  592 KAQLEKEINDRRLELQ-----------EFKILKDKKDAKIRELEARVSDLELEKVKLVnagSERLRAVKDIKQERDQLLN 660

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1984 GAQKGPANKSHAKELQELL----REKQQEVKQLQKDCIRYLERI-SALEKTVKALEFVHTESQKDLDVTKGNLAQAVEHR 2058
Cdd:pfam15921  661 EVKTSRNELNSLSEDYEVLkrnfRNKSEEMETTTNKLKMQLKSAqSELEQTRNTLKSMEGSDGHAMKVAMGMQKQITAKR 740

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2059 KKAQAELSSFKILLDDTQSeaARVLADNLKLKKELQSNKESIKSQIKQKDEDLLRRLEQAEEKHRKEKKNMQEKLDalhr 2138
Cdd:pfam15921  741 GQIDALQSKIQFLEEAMTN--ANKEKHFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANMEVALD---- 814

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1039751015 2139 eKAHVEetLAEIQVSLTRKDQE-----------MKELQG-------SLDSTLAQLAAFTKSMSSL 2185
Cdd:pfam15921  815 -KASLQ--FAECQDIIQRQEQEsvrlklqhtldVKELQGpgytsnsSMKPRLLQPASFTRTHSNV 876
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1584-2043 5.55e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 45.53  E-value: 5.55e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1584 SSKMAESTEWQEKHKELQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQ--ELYAKLRSTESDKREREKQLQDAEQEME 1661
Cdd:COG4717     77 EEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQllPLYQELEALEAELAELPERLEELEERLE 156

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1662 EMkekmrkfaKSKQQKILELEEENDRLRAEAQpvggtgesmEALLSSNSSLKEELEKITLEHKTLSKEFEALMAEKDALS 1741
Cdd:COG4717    157 EL--------RELEEELEELEAELAELQEELE---------ELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQ 219

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1742 EETRNLKLQVEAQVLKQASLEATEKSDEPKDVIEEVTQAVVGKSQERDALSDSAKLEDSEAILMGDGAKPGVSETFSSHD 1821
Cdd:COG4717    220 EELEELEEELEQLENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKAS 299

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1822 DIknylQQLDQLKGRIAELEMEKQKDRELSQALENEKNALLTQISAKDSELKLLEEEVTKRTTLNQQIQEELCRVTK--- 1898
Cdd:COG4717    300 LG----KEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQEIaal 375

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1899 LKETAEEEKDDLEERLM---------NQLAELNGSIGNYYQDVTD--AQIKNEQLESEMRNLQRCVSELEEEKQQLVKEK 1967
Cdd:COG4717    376 LAEAGVEDEEELRAALEqaeeyqelkEELEELEEQLEELLGELEEllEALDEEELEEELEELEEELEELEEELEELREEL 455

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1039751015 1968 TKVESEIRkeymekiqgaqkgpaNKSHAKELQELLREKQQEVKQLQkdciRYLERISALEKTVKALEFVHTESQKD 2043
Cdd:COG4717    456 AELEAELE---------------QLEEDGELAELLQELEELKAELR----ELAEEWAALKLALELLEEAREEYREE 512
MAD pfam05557
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ...
 1829-2318 6.02e-04

Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.


Pssm-ID: 461677 [Multi-domain]  Cd Length: 660  Bit Score: 45.50  E-value: 6.02e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1829 QLDQLKGRIAELEMEKQKDRELSQALENEKNALLTQISAKDSELKLLEEEVTKRTTLNQQIQEELCRVTKLKETAEEEKD 1908
Cdd:pfam05557   10 RLSQLQNEKKQMELEHKRARIELEKKASALKRQLDRESDRNQELQKRIRLLEKREAEAEEALREQAELNRLKKKYLEALN 89

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1909 DLEERLMNQLAELNGSIGNYYQDVTDAQIKNEQLESEmrnLQRCVSELEEEKQQLVKEKTKVEseirkEYMEKIQGAQKG 1988
Cdd:pfam05557   90 KKLNEKESQLADAREVISCLKNELSELRRQIQRAELE---LQSTNSELEELQERLDLLKAKAS-----EAEQLRQNLEKQ 161

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1989 P-ANKSHAKELQELLREKQQEV--KQLQKDCIRYLERISALEKTVKALEfvhtESQKDLDVTKGNLAQAVEHRKKAQAEL 2065
Cdd:pfam05557  162 QsSLAEAEQRIKELEFEIQSQEqdSEIVKNSKSELARIPELEKELERLR----EHNKHLNENIENKLLLKEEVEDLKRKL 237

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2066 SSFkillDDTQSEAARVLADNLKLKKELQSNKESIKSQIKQ--KDEDLLRRLEQAEekhrKEKKNMQEKLDALHREKAHV 2143
Cdd:pfam05557  238 ERE----EKYREEAATLELEKEKLEQELQSWVKLAQDTGLNlrSPEDLSRRIEQLQ----QREIVLKEENSSLTSSARQL 309

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2144 EETLAEIQVSLTRKDQEMKELQGSLDSTLAQLAAFTKSMSSLQDDRDRVIDEAKKWerrfgDAIQTKEEEVRLKEENCIA 2223
Cdd:pfam05557  310 EKARRELEQELAQYLKKIEDLNKKLKRHKALVRRLQRRVLLLTKERDGYRAILESY-----DKELTMSNYSPQLLERIEE 384

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2224 LKDQLRQMAIHMEELKITVSRLEHDKEIWESKAQTELQHHQKAydKLQEENKELTSQLEDARQLYHdsknELTKLESELK 2303
Cdd:pfam05557  385 AEDMTQKMQAHNEEMEAQLSVAEEELGGYKQQAQTLERELQAL--RQQESLADPSYSKEEVDSLRR----KLETLELERQ 458

                          490
                   ....*....|....*
gi 1039751015 2304 SLKDQTTDLNNSLEK 2318
Cdd:pfam05557  459 RLREQKNELEMELER 473
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1935-2389 6.09e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 45.68  E-value: 6.09e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1935 AQIKNEQLESEMRNLQRCVSELEEEKQQLVKEKTKVESEIRkEYMEKIQGAQkgpankshAKELQELlrekQQEVKQLQK 2014
Cdd:COG4913    286 AQRRLELLEAELEELRAELARLEAELERLEARLDALREELD-ELEAQIRGNG--------GDRLEQL----EREIERLER 352

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2015 DCIRYLERISALEKTVKALEFVHTESQKDLdvtKGNLAQAVEHRKKAQAELSSfkilLDDTQSEAARVLADNLKLKKELQ 2094
Cdd:COG4913    353 ELEERERRRARLEALLAALGLPLPASAEEF---AALRAEAAALLEALEEELEA----LEEALAEAEAALRDLRRELRELE 425

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2095 SNKESI---KSQIKQKDEDLLRRLEQA-----------------------------------------EEKHRK------ 2124
Cdd:COG4913    426 AEIASLerrKSNIPARLLALRDALAEAlgldeaelpfvgelievrpeeerwrgaiervlggfaltllvPPEHYAaalrwv 505

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2125 EKKNMQEKLDALHREKAHVEETLAEIQV-SLTRK-DQEMKELQGSLDSTLAQLAAFTK--SMSSLQDDRDRV-------- 2192
Cdd:COG4913    506 NRLHLRGRLVYERVRTGLPDPERPRLDPdSLAGKlDFKPHPFRAWLEAELGRRFDYVCvdSPEELRRHPRAItragqvkg 585

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2193 ------IDEAKKWERR--FG----DAIQTKEEEVRLKEENCIALKDQLRQMAIHMEELKITVSRLEHDKEIWESK----- 2255
Cdd:COG4913    586 ngtrheKDDRRRIRSRyvLGfdnrAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEidvas 665

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2256 AQTELQHHQKAYDKLQEEN---KELTSQLEDARQLYHDSKNELTKLESELKSLKDQTTDLNNSLEKCKEHENNLEGIIKQ 2332
Cdd:COG4913    666 AEREIAELEAELERLDASSddlAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARL 745

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1039751015 2333 QEAdiqnckfscEQLETDLAA--SRELTSRLHDEINAKEQKIISLLSGKEEAIQLAVEE 2389
Cdd:COG4913    746 ELR---------ALLEERFAAalGDAVERELRENLEERIDALRARLNRAEEELERAMRA 795
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 685-1241 8.10e-04

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 45.44  E-value: 8.10e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  685 GELERLKTQVLELETSLHTAE---ETYKRNLSEKVKEISSLTQLSEEVKESAEEARSTLAAVTEERDQLLYQVKEL-DVL 760
Cdd:TIGR02169  287 EEQLRVKEKIGELEAEIASLErsiAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELkEEL 366

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  761 AELRARVQELESSLAE-----AEKQRGLD------YESQRAQHNL------LTEQIHSLSIEAKSKDVKIEALQRELDGV 823
Cdd:TIGR02169  367 EDLRAELEEVDKEFAEtrdelKDYREKLEklkreiNELKRELDRLqeelqrLSEELADLNAAIAGIEAKINELEEEKEDK 446

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  824 QLQFCEQGTQMKTLQSQLEAKEREVREGTERLRDISQEMEGLSQALSQKE------------------------------ 873
Cdd:TIGR02169  447 ALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEaqaraseervrggraveevlkasiqgvhgt 526

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  874 --------------LEIAKMDQLLLEKQKDVETLQQTIQ-EKDQQVTELSFSMTEKMVQLNEEKfSLGVEIKTLKEQLNL 938
Cdd:TIGR02169  527 vaqlgsvgeryataIEVAAGNRLNNVVVEDDAVAKEAIElLKRRKAGRATFLPLNKMRDERRDL-SILSEDGVIGFAVDL 605

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  939 L--------------------SRTEEATK------------EQVEESGA--GSSLKLGHDESGQ--------------EG 970
Cdd:TIGR02169  606 VefdpkyepafkyvfgdtlvvEDIEAARRlmgkyrmvtlegELFEKSGAmtGGSRAPRGGILFSrsepaelqrlrerlEG 685

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  971 LQQELELLRKESEQRKRKLQAALINRKELLQKVSQLEEELAKVREDSRKEIPFGENERRKLEEdrenrddpeewgtskwr 1050
Cdd:TIGR02169  686 LKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSS----------------- 748

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1051 eveasLKQTISEKEVELEGIRRDLKEKTAAEEELQAVVQRMTRDL-----QSKTKQIDLLQEEVTENQATIQKLVTGTmd 1125
Cdd:TIGR02169  749 -----LEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLshsriPEIQAELSKLEEEVSRIEARLREIEQKL-- 821

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1126 agngGSAAPVKETAASSppgaggeehwKPELEGRILDLEKDKTQLQKKlQEALIARKAilkKAQEKEKQLKEELREQKDA 1205
Cdd:TIGR02169  822 ----NRLTLEKEYLEKE----------IQELQEQRIDLKEQIKSIEKE-IENLNGKKE---ELEEELEELEAALRDLESR 883

                          650       660       670
                   ....*....|....*....|....*....|....*.
gi 1039751015 1206 YHHLQGQFHEQNKEKENIADQLRQLQCQARESIDRQ 1241
Cdd:TIGR02169  884 LGDLKKERDELEAQLRELERKIEELEAQIEKKRKRL 919
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
710-1122 8.34e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 45.14  E-value: 8.34e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  710 RNLSEKVKEISSLTQLSEEVKESAEEARSTLAAVTEERDQLLYQVKELDVLAELRARVQELESSLAEAE--KQRGLDYES 787
Cdd:COG4717     81 KEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEALEAELAELPERLEelEERLEELRE 160

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  788 QRAQHNLLTEQIHSLSIEAKskdvkiEALQRELDGVQLQFCEQGTQMKTLQSQLEAKEREVREGTERLRDISQEMEGLSQ 867
Cdd:COG4717    161 LEEELEELEAELAELQEELE------ELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLEN 234

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  868 ALS----QKELEIAKMDQLLLEKQKDVETLQQTIQEKDQQVTELSFSMTEKMV----QLNEEKFSLGVEIKTLKEQLNLL 939
Cdd:COG4717    235 ELEaaalEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLAllflLLAREKASLGKEAEELQALPALE 314

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  940 SRTEEATKEQVEESGAGSSLKLGHDESGQEGLQQELELLRK-ESEQRKRKLQAALINRKELLQKVSQLEEELAKVREDSR 1018
Cdd:COG4717    315 ELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREaEELEEELQLEELEQEIAALLAEAGVEDEEELRAALEQA 394

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1019 KEIPFGENERRKLEEDRENRDDPEEWGTSKWreVEASLKQTISEKEVELEGIRRDLKEKTAAEEELQAVVQRMTRD--LQ 1096
Cdd:COG4717    395 EEYQELKEELEELEEQLEELLGELEELLEAL--DEEELEEELEELEEELEELEEELEELREELAELEAELEQLEEDgeLA 472

                          410       420
                   ....*....|....*....|....*.
gi 1039751015 1097 SKTKQIDLLQEEVTENQATIQKLVTG 1122
Cdd:COG4717    473 ELLQELEELKAELRELAEEWAALKLA 498
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 705-1111 8.64e-04

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 45.10  E-value: 8.64e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  705 EETYKRNLSEKVKEISSLTQLSEEVKESAEEARSTLAAVTEERDQLLYQVK-ELDVLAELRARVQELESSLAEAEKQRGL 783
Cdd:pfam05483  228 EEEYKKEINDKEKQVSLLLIQITEKENKMKDLTFLLEESRDKANQLEEKTKlQDENLKELIEKKDHLTKELEDIKMSLQR 307

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  784 DYESQRAQHNLLTEQIHSLSIEAKSKDVKIEALQRE-------LDGVQLQFCEQGTQMKTLQSQLEAKEREVREGTERLR 856
Cdd:pfam05483  308 SMSTQKALEEDLQIATKTICQLTEEKEAQMEELNKAkaahsfvVTEFEATTCSLEELLRTEQQRLEKNEDQLKIITMELQ 387

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  857 DISQEMEGLSQALSQKELEIAKM------DQLLLEKQKDVETLQQTIQEKDQQVTELSFSMTEKMVQLNEEKFSLGV-EI 929
Cdd:pfam05483  388 KKSSELEEMTKFKNNKEVELEELkkilaeDEKLLDEKKQFEKIAEELKGKEQELIFLLQAREKEIHDLEIQLTAIKTsEE 467

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  930 KTLKEQLNLLSRTEEATKEQVEESGAGSSLKLGHDESGQEGLQQELELLRKESE--QRKRKLQAALINRKELLQKVSQLE 1007
Cdd:pfam05483  468 HYLKEVEDLKTELEKEKLKNIELTAHCDKLLLENKELTQEASDMTLELKKHQEDiiNCKKQEERMLKQIENLEEKEMNLR 547

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1008 EELAKVREDSRKEipfGENERRKLEEDRENRDDPEEWGTSKWREVEASlkqtisekEVELEGIRRDLKEKTAAEEELQAV 1087
Cdd:pfam05483  548 DELESVREEFIQK---GDEVKCKLDKSEENARSIEYEVLKKEKQMKIL--------ENKCNNLKKQIENKNKNIEELHQE 616

                          410       420
                   ....*....|....*....|....
gi 1039751015 1088 VQRMTRDLQSKTKQIDLLQEEVTE 1111
Cdd:pfam05483  617 NKALKKKGSAENKQLNAYEIKVNK 640
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 690-1111 1.02e-03

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 45.01  E-value: 1.02e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  690 LKTQVLELE---TSLHTAEETYKRNLSEKVKEISSLTQLSEEVKESAEEARSTLAAVTEERDQLLYQVKELDvlaelrAR 766
Cdd:TIGR04523  216 LESQISELKkqnNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELE------KQ 289

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  767 VQELESSLAEAEKQRGLDYESQ-RAQHNLLTEQIHSLSIEAKSKDVKIEALQRELDGVQLQFCEQGTQMKTLQSQLEAKE 845
Cdd:TIGR04523  290 LNQLKSEISDLNNQKEQDWNKElKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQ 369

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  846 REVREGTERLRDISQEMEGLSQALSQKELEIAKMDQLLLEKQKDVETLQQTIQEKDQQVTELSfsmtEKMVQLNEEKFSL 925
Cdd:TIGR04523  370 NEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLK----ETIIKNNSEIKDL 445

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  926 GVEIKTLKEQLNLLSRTEEATKEQVEESgagsslklghdESGQEGLQQELELLRKESEQRKRKLQAALINRKELLQKVSQ 1005
Cdd:TIGR04523  446 TNQDSVKELIIKNLDNTRESLETQLKVL-----------SRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKD 514

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1006 LEEELAKVREDSRKEipfgenERRKLEEDRENRDDPEEWGTSKWREVEASLKQTISEKEVELEGIRRDLKEKTAAEEELQ 1085
Cdd:TIGR04523  515 LTKKISSLKEKIEKL------ESEKKEKESKISDLEDELNKDDFELKKENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQ 588

                          410       420
                   ....*....|....*....|....*.
gi 1039751015 1086 AVVQRMTRDLQSKTKQIDLLQEEVTE 1111
Cdd:TIGR04523  589 ELIDQKEKEKKDLIKEIEEKEKKISS 614
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 1902-2149 1.06e-03

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 44.92  E-value: 1.06e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1902 TAEEEKDDLEERLMN----QLAELNGSIGNYYqdvtdaqikNEQLESEMRNLQRCVSELEEEKQqlvKEKTKVESEIRKE 1977
Cdd:PRK05771    13 TLKSYKDEVLEALHElgvvHIEDLKEELSNER---------LRKLRSLLTKLSEALDKLRSYLP---KLNPLREEKKKVS 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1978 YMEKIQGAQKGPANKShakELQELLREKQQEVKQLQkdcirylERISALEKTVKALEFVhtesqKDLDV------TKGNL 2051
Cdd:PRK05771    81 VKSLEELIKDVEEELE---KIEKEIKELEEEISELE-------NEIKELEQEIERLEPW-----GNFDLdlslllGFKYV 145

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2052 AQAVEHRKKAQAELSS--------------------FKILLDDTQSEAARVLADNLKLKKELQ---------SNKESIKS 2102
Cdd:PRK05771   146 SVFVGTVPEDKLEELKlesdvenveyistdkgyvyvVVVVLKELSDEVEEELKKLGFERLELEeegtpseliREIKEELE 225

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*..
gi 1039751015 2103 QIKQKDEDLLRRLEQAEEKHRKEKKNMQEKLDALhREKAHVEETLAE 2149
Cdd:PRK05771   226 EIEKERESLLEELKELAKKYLEELLALYEYLEIE-LERAEALSKFLK 271
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 1828-1981 1.22e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 43.37  E-value: 1.22e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1828 QQLDQLKGRIAELEMEKQKDRELSQALENEKNALLTQISAKDSELKLLEEEVTKRTTLNQQIQEELCRVTKLKE------ 1901
Cdd:COG1579     17 SELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVRNNKEyealqk 96

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1902 ---TAEEEKDDLEERLMNQLAELNGSIGNYYQDVTDAQIKNEQLESEMRNLQRCVSELEEEKQQLVKEKTKVESEIRKEY 1978
Cdd:COG1579     97 eieSLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAEREELAAKIPPEL 176


                   ...
gi 1039751015 1979 MEK 1981
Cdd:COG1579    177 LAL 179
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1376-1759 1.22e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 44.37  E-value: 1.22e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1376 LKTLQPELDALHKHMGQK---------------------EEEVNYLYGQLSEKEQTLTTVQTEMVEQERLIKALHT---- 1430
Cdd:COG4717     48 LERLEKEADELFKPQGRKpelnlkelkeleeelkeaeekEEEYAELQEELEELEEELEELEAELEELREELEKLEKllql 127

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1431 --------QLEMQAKEHEERLKQAQVEICELKKKPTELEEETNAKQQLQRKLQAALISRKEALKEN-KSLQEQLSSARDA 1501
Cdd:COG4717    128 lplyqeleALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEElQDLAEELEELQQR 207

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1502 VERLTKSLADVESQVSVQNQEKDAVLGKLTILQEERDKLIAEMDRF----LLENQSLSGSCESLKLALGGL--------- 1568
Cdd:COG4717    208 LAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLLLLiaaaLLALLGLGGSLLSLILTIAGVlflvlglla 287

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1569 ---------TEDKEKLMEELESVRSSKMAESTEWQEKHKELQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQELyakl 1639
Cdd:COG4717    288 llflllareKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEEL---- 363

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1640 rSTESDKREREKQLQDAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEAqpvggTGESMEALLSSNSSLKEELEKI 1719
Cdd:COG4717    364 -QLEELEQEIAALLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELL-----GELEELLEALDEEELEEELEEL 437

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|
gi 1039751015 1720 TLEHKTLSKEFEALMAEKDALSEETRNLKLQVEAQVLKQA 1759
Cdd:COG4717    438 EEELEELEEELEELREELAELEAELEQLEEDGELAELLQE 477
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 690-1420 1.25e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 44.67  E-value: 1.25e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  690 LKTQVLELETSLHTAE-ETYKRNLSEKVKEISSLTQLSEEVKESAEEARSTLAAVTEERDQLLYQVKEL--DVLAELRAR 766
Cdd:TIGR02169  216 LLKEKREYEGYELLKEkEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLgeEEQLRVKEK 295

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  767 VQELESSLAEAE------KQRGLDYESQRAQhnlLTEQIHSLSIEAKSKDVKIEALQRELDGVQLQFCEQGTQMKTLQSQ 840
Cdd:TIGR02169  296 IGELEAEIASLErsiaekERELEDAEERLAK---LEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAE 372

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  841 LEAKEREVREGTERLRDISQEMEGLSQALSQKELEIAKMDQLLLEKQKDVETLQQTIQEKDQQVTELSFSMTEK------ 914
Cdd:TIGR02169  373 LEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKaleikk 452

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  915 -----------MVQLNEEKFSLGVEIKTLKEQLNLLSR---TEEATKEQVEESGAGSSLKLGHDESGQEGLQQELELLRK 980
Cdd:TIGR02169  453 qewkleqlaadLSKYEQELYDLKEEYDRVEKELSKLQRelaEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLGS 532

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  981 ESEQRKRKLQAALINRKELL----QKVSQLEEELAKVREDSRKE-IPFGENERRKLEEDRENRD------------DPEE 1043
Cdd:TIGR02169  533 VGERYATAIEVAAGNRLNNVvvedDAVAKEAIELLKRRKAGRATfLPLNKMRDERRDLSILSEDgvigfavdlvefDPKY 612

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1044 WGTSKW--------REVEASLKQTISEKEVELEGirrDLKEKTAA--------------EEELQAVVQRMTRDLQSKTKQ 1101
Cdd:TIGR02169  613 EPAFKYvfgdtlvvEDIEAARRLMGKYRMVTLEG---ELFEKSGAmtggsraprggilfSRSEPAELQRLRERLEGLKRE 689

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1102 IDLLQEEVTEnqatIQKLVTGTMDAGnggSAAPVKETAASSPPGAGGEEHWKpeLEGRILDLEKDKTQLQKKLQEALIAR 1181
Cdd:TIGR02169  690 LSSLQSELRR----IENRLDELSQEL---SDASRKIGEIEKEIEQLEQEEEK--LKERLEELEEDLSSLEQEIENVKSEL 760

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1182 KAILKKAQEKEKQLKEELREQKDAYHHLQGQFHEQ-NKEKENIADQLRQLQCQAREsIDRQLPgtgqqepgppAPSLEGI 1260
Cdd:TIGR02169  761 KELEARIEELEEDLHKLEEALNDLEARLSHSRIPEiQAELSKLEEEVSRIEARLRE-IEQKLN----------RLTLEKE 829

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1261 SLEDTEPASESDLHAAQPSPPGETAALQA-TVSVAQIQAQLKEMEVEKEELELKVSSIASELAKKSEEVLLLQDQINEQG 1339
Cdd:TIGR02169  830 YLEKEIQELQEQRIDLKEQIKSIEKEIENlNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELE 909

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1340 LEIQNLKAASVEAQAHTELLKQELESSQLKVAGLEHLKTLQPELDALHKHMGQKEEEVNYL-----------------YG 1402
Cdd:TIGR02169  910 AQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELSLEDVQAELQRVEEEIRALepvnmlaiqeyeevlkrLD 989

                          810
                   ....*....|....*...
gi 1039751015 1403 QLSEKEQTLTTVQTEMVE 1420
Cdd:TIGR02169  990 ELKEKRAKLEEERKAILE 1007
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 832-1036 1.28e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 44.05  E-value: 1.28e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  832 TQMKTLQSQLEAKEREVREGTERLRDISQEMEGLSQALSQKELEIAKMDQLLLEKQKDVETLQQTIQEKDQQVTELSFSM 911
Cdd:COG3883     16 PQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARAL 95

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  912 TEKMVQLNEEKFSLGVE-IKTLKEQLNLLSRTEEATKEQVEESGAgSSLKLGHDESGQEGLQQELELLRKESEQRKRKLQ 990
Cdd:COG3883     96 YRSGGSVSYLDVLLGSEsFSDFLDRLSALSKIADADADLLEELKA-DKAELEAKKAELEAKLAELEALKAELEAAKAELE 174

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*.
gi 1039751015  991 AALINRKELLQKVSQLEEELAKVREDSRKEIPFGENERRKLEEDRE 1036
Cdd:COG3883    175 AQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAA 220
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 2614-3057 1.30e-03

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 44.83  E-value: 1.30e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2614 QLKAKEEELQRLNMALSSSQKRTADLEEELVCVQKEATRKVSEIEDQLKKELKHLHHDAGIMRNETETAEERVAELARDL 2693
Cdd:pfam12128  252 TLESAELRLSHLHFGYKSDETLIASRQEERQETSAELNQLLRTLDDQWKEKRDELNGELSAADAAVAKDRSELEALEDQH 331

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2694 VEMEQKLLTVTKENKDLMAQIQAfgrSMSSLQDSRDHATEELGDLKKKYDA--------SLKELAQLKEWQDSSREGDVL 2765
Cdd:pfam12128  332 GAFLDADIETAAADQEQLPSWQS---ELENLEERLKALTGKHQDVTAKYNRrrskikeqNNRDIAGIKDKLAKIREARDR 408

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2766 SQAAfplstSENVLSRLE-----KLNQQLTSKDEQLLHLSS---ELESSHNQVQSISKAMTSLQNERDRL---WSELEKF 2834
Cdd:pfam12128  409 QLAV-----AEDDLQALEselreQLEAGKLEFNEEEYRLKSrlgELKLRLNQATATPELLLQLENFDERIeraREEQEAA 483

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2835 RKSEEGKQRAAAPSAASSPAEVQSLKKAMSSLQNDRDRllkeLKNLQQQYLQMSQEMTELRPLKAQLQEsQDQTKAL--- 2911
Cdd:pfam12128  484 NAEVERLQSELRQARKRRDQASEALRQASRRLEERQSA----LDELELQLFPQAGTLLHFLRKEAPDWE-QSIGKVIspe 558

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2912 ---------QVMEEELRQENLSWQHELRQLRMEKNSWELHERRMKE---QFLMAISDKDQQLGHLQSLLRELRSSSQAQI 2979
Cdd:pfam12128  559 llhrtdldpEVWDGSVGGELNLYGVKLDLKRIDVPEWAASEEELRErldKAEEALQSAREKQAAAEEQLVQANGELEKAS 638

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1039751015 2980 LSTQYQRQASPETSASLdgsQKLVYETELLRTQLNDSLKEihqkelRIQQLNSKFSQLLEEKNVLSTQLSDASQSLRE 3057
Cdd:pfam12128  639 REETFARTALKNARLDL---RRLFDEKQSEKDKKNKALAE------RKDSANERLNSLEAQLKQLDKKHQAWLEEQKE 707
HMMR_N pfam15905
Hyaluronan mediated motility receptor N-terminal; HMMR_N is the N-terminal region of ...
 870-1119 1.33e-03

Hyaluronan mediated motility receptor N-terminal; HMMR_N is the N-terminal region of eukaryotic hyaluronan-mediated motility receptor proteins. The protein is functionally associated with BRCA1 and thus predicted to be a common, low-penetrance breast cancer candidate.


Pssm-ID: 464932 [Multi-domain]  Cd Length: 329  Bit Score: 44.03  E-value: 1.33e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  870 SQKELEIAKmDQLLLEKQKDVETLQQTIQEKDQQVTELSFSMTE-KMVQLNEEKFSLGVEIKTLKEQLNLLSRTEEATKE 948
Cdd:pfam15905   65 SQKNLKESK-DQKELEKEIRALVQERGEQDKRLQALEEELEKVEaKLNAAVREKTSLSASVASLEKQLLELTRVNELLKA 143

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  949 QVEESGAGSSLKLGHDESGQegLQQELELLRKE----SEQRKRKLQAALINRKELLQKVSQLEEELAKVREDSRKE---- 1020
Cdd:pfam15905  144 KFSEDGTQKKMSSLSMELMK--LRNKLEAKMKEvmakQEGMEGKLQVTQKNLEHSKGKVAQLEEKLVSTEKEKIEEkset 221

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1021 ------IPFGENERRKLEEDRENRDDPEEWGTSKWREVEaSLKQTISEKEVELEGIRRDLKEKTA-AEEELQAVVQRMTR 1093
Cdd:pfam15905  222 eklleyITELSCVSEQVEKYKLDIAQLEELLKEKNDEIE-SLKQSLEEKEQELSKQIKDLNEKCKlLESEKEELLREYEE 300

                          250       260
                   ....*....|....*....|....*.
gi 1039751015 1094 DLQSKTKQIDLLQEEVTENQATIQKL 1119
Cdd:pfam15905  301 KEQTLNAELEELKEKLTLEEQEHQKL 326
PRK11281 PRK11281
mechanosensitive channel MscK;
154-375 1.33e-03

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 44.52  E-value: 1.33e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  154 ELQEKEKLISSLQAQLDQSEQASQLDKSSAEMEDFVLMKQ-QLQEKEE-------LISTLQTQLSQTQAEQAAQLSSMQQ 225
Cdd:PRK11281    95 KLRQAQAELEALKDDNDEETRETLSTLSLRQLESRLAQTLdQLQNAQNdlaeynsQLVSLQTQPERAQAALYANSQRLQQ 174

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  226 VVREKDARFETQVRLHEDELLQLVTQS---DVETEMQQKL----RVMQRKLEEHEEALLGRAQV----VDLLQ-----KE 289
Cdd:PRK11281   175 IRNLLKGGKVGGKALRPSQRVLLQAEQallNAQNDLQRKSlegnTQLQDLLQKQRDYLTARIQRlehqLQLLQeainsKR 254

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  290 LTSAEQRNQVLSQQLQLLEAEHNTL-KNTMETERQESKTLMEKVELEVAerkLSFHNLQeemhqLQGQLERAGQAQADLE 368
Cdd:PRK11281   255 LTLSEKTVQEAQSQDEAARIQANPLvAQELEINLQLSQRLLKATEKLNT---LTQQNLR-----VKNWLDRLTQSERNIK 326


                   ....*..
gi 1039751015  369 TQYSALQ 375
Cdd:PRK11281   327 EQISVLK 333
PRK12704 PRK12704
phosphodiesterase; Provisional
 1167-1242 1.34e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 44.38  E-value: 1.34e-03
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1039751015 1167 KTQLQKKLQEALIARKAILKKAQEKEKQLKEE-LREQKDAYHHLQGQFHEQNKEKEN-IADQLRQLQcQARESIDRQL 1242
Cdd:PRK12704    26 KKIAEAKIKEAEEEAKRILEEAKKEAEAIKKEaLLEAKEEIHKLRNEFEKELRERRNeLQKLEKRLL-QKEENLDRKL 102
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1054-1259 1.35e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.98  E-value: 1.35e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1054 ASLKQTISEKEVELEGIRRDLKEKTAAEEELQAVVQRMTRDLQSKTKQIDLLQEEVTENQATIQKLVTGTMDAGNGGSAA 1133
Cdd:COG4942     44 AALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELAELLRALYRLGRQPPLA 123

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1134 PVkeTAASSPPGAGGEEHW----KPELEGRILDLEKDKTQLQKKLQEALIARK---AILKKAQEKEKQLKEELREQKDAY 1206
Cdd:COG4942    124 LL--LSPEDFLDAVRRLQYlkylAPARREQAEELRADLAELAALRAELEAERAeleALLAELEEERAALEALKAERQKLL 201

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1039751015 1207 HHLQGQFHEQNKEKENIADQLRQLQcQARESIDRQLPGTGQQEPGPPAPSLEG 1259
Cdd:COG4942    202 ARLEKELAELAAELAELQQEAEELE-ALIARLEAEAAAAAERTPAAGFAALKG 253
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 759-1380 1.36e-03

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 44.72  E-value: 1.36e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  759 VLAELRARVQELESSLAEAEKQ-RGLDYESQRAQHNLLteQIHSLSIEAKSKDVKIEalqreLDGVQLQFCEQGTQMKTL 837
Cdd:pfam15921  225 ILRELDTEISYLKGRIFPVEDQlEALKSESQNKIELLL--QQHQDRIEQLISEHEVE-----ITGLTEKASSARSQANSI 297

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  838 QSQLEAKEREVREGTerlrdiSQEMEGLSqalsqkELEiAKMDQLLLEKQKDVETLQQTIQEKDQQVTELSFSMTEKMV- 916
Cdd:pfam15921  298 QSQLEIIQEQARNQN------SMYMRQLS------DLE-STVSQLRSELREAKRMYEDKIEELEKQLVLANSELTEARTe 364

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  917 --QLNEEKFSLGVEIKTLKEQLNLLSRTEEATKEQ---VEESGAGSSLKLGH-----DESGQE--GLQQELELLRKESEQ 984
Cdd:pfam15921  365 rdQFSQESGNLDDQLQKLLADLHKREKELSLEKEQnkrLWDRDTGNSITIDHlrrelDDRNMEvqRLEALLKAMKSECQG 444

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  985 RKRKLQAALINRKELLQKVSQLEEELAKVREDSRKEIPFGENERRKLEEDRENRDDPEEWGTSKWREVEAS------LKQ 1058
Cdd:pfam15921  445 QMERQMAAIQGKNESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEATnaeitkLRS 524

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1059 TISEKEVELEGIRRDLKEKTAAEEELQAVVQRMTrdlqSKTKQIDLLQEEVtENQATIQKLVTGTMDAGNGGSAAPVKET 1138
Cdd:pfam15921  525 RVDLKLQELQHLKNEGDHLRNVQTECEALKLQMA----EKDKVIEILRQQI-ENMTQLVGQHGRTAGAMQVEKAQLEKEI 599

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1139 ------AASSPPGAGGEEHWKPELEGRILDLEKDKTQLQKKLQEALIARKAIlkkAQEKEKQLKE------ELREQKDAY 1206
Cdd:pfam15921  600 ndrrleLQEFKILKDKKDAKIRELEARVSDLELEKVKLVNAGSERLRAVKDI---KQERDQLLNEvktsrnELNSLSEDY 676

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1207 HHLQGQFHEQNKEKENIADQLRqLQCQARESIDRQLPGTGQQEPGPPAPSLE-GISLEDTEPASESDLHAAQpsppGETA 1285
Cdd:pfam15921  677 EVLKRNFRNKSEEMETTTNKLK-MQLKSAQSELEQTRNTLKSMEGSDGHAMKvAMGMQKQITAKRGQIDALQ----SKIQ 751

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1286 ALQATVSVAqiQAQLKEMEVEKEELELKVSSIASELAKKSEEVLLLQDQINEQGLEIQNL-----KAASVEAQAHTELLK 1360
Cdd:pfam15921  752 FLEEAMTNA--NKEKHFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANMevaldKASLQFAECQDIIQR 829

                          650       660
                   ....*....|....*....|
gi 1039751015 1361 QELESSQLKVAGLEHLKTLQ 1380
Cdd:pfam15921  830 QEQESVRLKLQHTLDVKELQ 849
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
838-1077 1.50e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 44.52  E-value: 1.50e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  838 QSQLEAKEREVREGTERLRDISQEMEGLSQALS--QKELEIAKMDQLLLEKQKDVETLQQTIQEKDQQVTELSFSMtekm 915
Cdd:COG4913    609 RAKLAALEAELAELEEELAEAEERLEALEAELDalQERREALQRLAEYSWDEIDVASAEREIAELEAELERLDASS---- 684

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  916 vqlneekfslgVEIKTLKEQLnllsrteeatkeqveesgagsslklghdesgqEGLQQELELLRKESEQRKRKLQAALIN 995
Cdd:COG4913    685 -----------DDLAALEEQL--------------------------------EELEAELEELEEELDELKGEIGRLEKE 721

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  996 RKELLQKVSQLEEELAKVREDSRKEIPFGENERRKLEEDRENRDDPEEWgtskWREVEASLKQTISEKEVELEGIRRDLK 1075
Cdd:COG4913    722 LEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGDAVERELREN----LEERIDALRARLNRAEEELERAMRAFN 797


                   ..
gi 1039751015 1076 EK 1077
Cdd:COG4913    798 RE 799
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
2712-2883 1.67e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 44.14  E-value: 1.67e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2712 AQIQAFGRSMSSLQDSRDHATEELGDLKKKYDASLKELAQLKEWQDSSREGDVLSQAAFPLSTSENVLSRLEKLNQQLTS 2791
Cdd:COG4913    610 AKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEIDVASAEREIAELEAELERLDASSDDLAA 689

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2792 KDEQLLHLSSELESSHNQVQSISKAMTSLQNERDRLWSELEKFRKSEEGKQRAAAPSAASSPAEV-------QSLKKAMS 2864
Cdd:COG4913    690 LEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERfaaalgdAVERELRE 769

                          170
                   ....*....|....*....
gi 1039751015 2865 SLQNDRDRLLKELKNLQQQ 2883
Cdd:COG4913    770 NLEERIDALRARLNRAEEE 788
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1953-2336 1.70e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 43.99  E-value: 1.70e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1953 VSELEEEKQQLVKEKTKVESEIRKEYMEKIQGAQKGPANKSHAKELQELLREKQQEVKQLQKDCIRYLERISALEKTVKA 2032
Cdd:COG4717     48 LERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQL 127

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2033 LEfvhtesqkdldvtkgnlaqAVEHRKKAQAELSSFKILLDDTQSEAARVladnlklkKELQSNKESIKSQIKQKDEDLL 2112
Cdd:COG4717    128 LP-------------------LYQELEALEAELAELPERLEELEERLEEL--------RELEEELEELEAELAELQEELE 180

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2113 RRLEQAEEKHRKEKKNMQEKLDALHREKAHVEETLAEIQVSLTRKDQEMKELQGSLDS---------------------- 2170
Cdd:COG4717    181 ELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAaaleerlkearlllliaaalla 260

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2171 -------------------------TLAQLAAFTKSMSSLQDDRDRVIDEA----------KKWERRFGDAIQTKEEEVR 2215
Cdd:COG4717    261 llglggsllsliltiagvlflvlglLALLFLLLAREKASLGKEAEELQALPaleeleeeelEELLAALGLPPDLSPEELL 340

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2216 LKEENCIALKDQLRQMAIHMEELKITVSRLEHDKEIWESKAQTE-----LQHHQKAYDKLQEENKELTSQLEDARQLYHD 2290
Cdd:COG4717    341 ELLDRIEELQELLREAEELEEELQLEELEQEIAALLAEAGVEDEeelraALEQAEEYQELKEELEELEEQLEELLGELEE 420

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|....*...
gi 1039751015 2291 SKNELTK--LESELKSLKDQTTDLNNSLEKCKEHENNLEGIIKQQEAD 2336
Cdd:COG4717    421 LLEALDEeeLEEELEELEEELEELEEELEELREELAELEAELEQLEED 468
PLN03229 PLN03229
acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional
 684-1037 1.94e-03

acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional


Pssm-ID: 178768 [Multi-domain]  Cd Length: 762  Bit Score: 44.07  E-value: 1.94e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  684 QGELERLKTQVLELETSLHTAEETYKRNLSEKVKEISSLtQLSEEVKESAEEARstLAAVTEE------RDQLLYQVkel 757
Cdd:PLN03229   435 EGEVEKLKEQILKAKESSSKPSELALNEMIEKLKKEIDL-EYTEAVIAMGLQER--LENLREEfskansQDQLMHPV--- 508

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  758 dvLAELRARV-QELESSLAEAEkqrglDYESQRAQHNLLTEqiHSLSIEAKSKDVKIEALQRELDgvqlQFCEQGTQMKT 836
Cdd:PLN03229   509 --LMEKIEKLkDEFNKRLSRAP-----NYLSLKYKLDMLNE--FSRAKALSEKKSKAEKLKAEIN----KKFKEVMDRPE 575

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  837 LQSQLEA-KEREVREGTERLRDISQEM-EGLSQALSQKELEIAK----MD-QLLLEKQKDVETLQQTIQEkdqqvtelsf 909
Cdd:PLN03229   576 IKEKMEAlKAEVASSGASSGDELDDDLkEKVEKMKKEIELELAGvlksMGlEVIGVTKKNKDTAEQTPPP---------- 645

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  910 SMTEKMVQLNEEkfsLGVEIKTLKEQLNLLSRTEEatkeqveesgagssLKLGHDESGQEGLQQELELLRKESEQRKRKL 989
Cdd:PLN03229   646 NLQEKIESLNEE---INKKIERVIRSSDLKSKIEL--------------LKLEVAKASKTPDVTEKEKIEALEQQIKQKI 708

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*...
gi 1039751015  990 QAALiNRKELLQKVSQLEEELAKVREDSRkeipfGENERRKLEEDREN 1037
Cdd:PLN03229   709 AEAL-NSSELKEKFEELEAELAAARETAA-----ESNGSLKNDDDKEE 750
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
2534-2972 1.98e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 43.99  E-value: 1.98e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2534 IKDSQQKQLLDAQLQQNKELRNECTKLEERLKGLEAEKQSLQMSSDALQKEKQGLSKEIKNLQTQLTALQEEGTLGVYHA 2613
Cdd:COG4717     67 ELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEALEAELAELPE 146

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2614 Q---LKAKEEELQRLNMALSSSQKRTADLEEELVCVQKEATRKVSEIEDQLKKELKHLHHDAGIMRNETETAEERVAELA 2690
Cdd:COG4717    147 RleeLEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELE 226

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2691 RDLVEMEQKLLTVTKENKDLMAQIQAFGRSMSSLQDSRDHATEELGDLKKKYDASLKELAQL-------KEWQDSSREGD 2763
Cdd:COG4717    227 EELEQLENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALlflllarEKASLGKEAEE 306

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2764 VLSQAAFPLSTSENVLSRLEKLNQQLTSKDEQLLHLSSELESSHNQVQSISKAMTSLQneRDRLWSELEKFRKSEEGKQR 2843
Cdd:COG4717    307 LQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQ--LEELEQEIAALLAEAGVEDE 384

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2844 AAAPSAASSPAEVQSLKKAMSSLQNDRDRLLKELKNLqqqylqmsQEMTELRPLKAQLQESQDQTKALQVMEEELRQENL 2923
Cdd:COG4717    385 EELRAALEQAEEYQELKEELEELEEQLEELLGELEEL--------LEALDEEELEEELEELEEELEELEEELEELREELA 456

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2924 SWQHELRQLRMEKNSWEL-HERRMKEQFLMAISDKDQQLGHLQSLLRELR 2972
Cdd:COG4717    457 ELEAELEQLEEDGELAELlQELEELKAELRELAEEWAALKLALELLEEAR 506
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1317-2075 2.08e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 43.90  E-value: 2.08e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1317 IASELAKKSEEVLLLQDQINEQGLEI----QNLKAASVEAQAHTE----LLKQELESSQLKVAGLEH-LKTLQPELDALH 1387
Cdd:TIGR02169  242 IERQLASLEEELEKLTEEISELEKRLeeieQLLEELNKKIKDLGEeeqlRVKEKIGELEAEIASLERsIAEKERELEDAE 321

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1388 KHMGQKEEEVNYLYGQLSEKEQTLTTVQTEMVEQERLIKALHTQLEMQAKEHEERLKQAQVEICELKKKPTELEEETNAK 1467
Cdd:TIGR02169  322 ERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREI 401

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1468 QQLQRklqaalisrkealkENKSLQEQLSSARDAVERLTKSLADVEsqvsvqnqekdavlGKLTILQEERDKLIAEMDRF 1547
Cdd:TIGR02169  402 NELKR--------------ELDRLQEELQRLSEELADLNAAIAGIE--------------AKINELEEEKEDKALEIKKQ 453

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1548 LLENQSLSGSCESLKLALGGLTEDKEKLMEELESVRSskmaestEWQEKHKELQKEYEVLLQSYENVSNEAERIQHVVES 1627
Cdd:TIGR02169  454 EWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQR-------ELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGT 526

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1628 VRQ--EKQELYAKLRSTESDKRerekqLQDAEQEMEEMKEKMRKFAKSKQ---------QKILELEEENDRLR------- 1689
Cdd:TIGR02169  527 VAQlgSVGERYATAIEVAAGNR-----LNNVVVEDDAVAKEAIELLKRRKagratflplNKMRDERRDLSILSedgvigf 601

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1690 -------------AEAQPVGGTG--ESMEA---------LLSSNSSLKEELEKITLEHKTLSKEFEALMAEKDALSEETR 1745
Cdd:TIGR02169  602 avdlvefdpkyepAFKYVFGDTLvvEDIEAarrlmgkyrMVTLEGELFEKSGAMTGGSRAPRGGILFSRSEPAELQRLRE 681

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1746 NL-KLQVEAQVLKQASLEATEKSDEPKDVIEEVTQAVVGKSQERDALSD-----SAKLEDSEAILMgdgakpgvsetfSS 1819
Cdd:TIGR02169  682 RLeGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQeeeklKERLEELEEDLS------------SL 749

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1820 HDDIKNYLQQLDQLKGRIAELEMEKQKDRELSQALENEKNAllTQISAKDSELKLLEEEVTKRTTLNQQIQEELCRVTKL 1899
Cdd:TIGR02169  750 EQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSH--SRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLE 827

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1900 KETAEEEKDDLEErlmnQLAELNGSIGNYYQDVTDAQIKNEQLESEMRNLQRCVSELEEEKQQLVKEKTKVESEIRKEYM 1979
Cdd:TIGR02169  828 KEYLEKEIQELQE----QRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELER 903

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1980 EKIQGAQKGPANKSHAKELQELLREKQQEVKQLQKDCIRYLE-------------RISALEKTVKALEFVHTESQKDLDV 2046
Cdd:TIGR02169  904 KIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEipeeelsledvqaELQRVEEEIRALEPVNMLAIQEYEE 983

                          810       820
                   ....*....|....*....|....*....
gi 1039751015 2047 TKGNLAQAVEHRKKAQAELSSFKILLDDT 2075
Cdd:TIGR02169  984 VLKRLDELKEKRAKLEEERKAILERIEEY 1012
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1047-1299 2.13e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 43.28  E-value: 2.13e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1047 SKWREVEASLKQTISEKEVELEGIRRDLKEKTAAEEELQAVVQRMTRDLQSKTKQIDLLQEEVTENQATIQKLVTGTMDA 1126
Cdd:COG3883     19 QAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARALYRS 98

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1127 GNGGSAAPVKETAASSppgagGEEHWKPELEGRILDLEKDKTQLQKKLQEALIARKAILKKAQEKEKQLKEELREQKDAy 1206
Cdd:COG3883     99 GGSVSYLDVLLGSESF-----SDFLDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAE- 172

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1207 hhLQGQFHEQNKEKENIADQLRQLQcQARESIDRQLPGTGQQEPGPPAPSLEGISLEDTEPASESDLHAAQPSPPGETAA 1286
Cdd:COG3883    173 --LEAQQAEQEALLAQLSAEEAAAE-AQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAASAAGA 249

                          250
                   ....*....|...
gi 1039751015 1287 LQATVSVAQIQAQ 1299
Cdd:COG3883    250 GAAGAAGAAAGSA 262
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 1836-2431 2.14e-03

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 43.94  E-value: 2.14e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1836 RIAELEMEKQKDRELSQALENEKNALLTQISakdsELKLLEEevTKRTTLNQQIQEELCRVTKLKETAEEEKDDLEER-- 1913
Cdd:pfam05483  170 KTKKYEYEREETRQVYMDLNNNIEKMILAFE----ELRVQAE--NARLEMHFKLKEDHEKIQHLEEEYKKEINDKEKQvs 243

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1914 -LMNQLAELNGSIGNYYQDVTDAQIKNEQLESEMRNLQRCVSELEEEKQQLVKEKTKVeseirKEYMEKIQGAQKGPANK 1992
Cdd:pfam05483  244 lLLIQITEKENKMKDLTFLLEESRDKANQLEEKTKLQDENLKELIEKKDHLTKELEDI-----KMSLQRSMSTQKALEED 318

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1993 SH--AKELQELLREKQQEVKQLQKDCIRYLERISALEKTVKALEFVHTESQKDLDVTKGNLAQAVEHRKKAQAELSSFKI 2070
Cdd:pfam05483  319 LQiaTKTICQLTEEKEAQMEELNKAKAAHSFVVTEFEATTCSLEELLRTEQQRLEKNEDQLKIITMELQKKSSELEEMTK 398

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2071 LLDDTQ---SEAARVLADNLKLKKElQSNKESIKSQIKQKDEDLLRRLEQAEekhrKEKKNMQEKLDALHREKAHVEETL 2147
Cdd:pfam05483  399 FKNNKEvelEELKKILAEDEKLLDE-KKQFEKIAEELKGKEQELIFLLQARE----KEIHDLEIQLTAIKTSEEHYLKEV 473

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2148 AEIQVSLTRKDQEMKELQGSLDSTLAQLAAFTKSMS----SLQDDRDRVIDEAKKWERRFGDAIQTKEEEVRLKEE---- 2219
Cdd:pfam05483  474 EDLKTELEKEKLKNIELTAHCDKLLLENKELTQEASdmtlELKKHQEDIINCKKQEERMLKQIENLEEKEMNLRDElesv 553

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2220 ------NCIALKDQLRQMAIHMEELKITVSRLEHDKEIWESKA---QTELQHHQKAYDKLQEENKELTSQLEDARQLYHD 2290
Cdd:pfam05483  554 reefiqKGDEVKCKLDKSEENARSIEYEVLKKEKQMKILENKCnnlKKQIENKNKNIEELHQENKALKKKGSAENKQLNA 633

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2291 SKNELTKLESELKSLKDQTTDLNNSLEKCKE----HENNLEGIIKQQEADI-------QNCKFSCEQLETDLAASRELTS 2359
Cdd:pfam05483  634 YEIKVNKLELELASAKQKFEEIIDNYQKEIEdkkiSEEKLLEEVEKAKAIAdeavklqKEIDKRCQHKIAEMVALMEKHK 713

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1039751015 2360 RLHDEINAKEQKIISLLSGKEEAIQLAVEELHQQHSKEIKELENLLSQEEEENVALEEENKRALEKTNQLTE 2431
Cdd:pfam05483  714 HQYDKIIEERDSELGLYKNKEQEQSSAKAALEIELSNIKAELLSLKKQLEIEKEEKEKLKMEAKENTAILKD 785
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2271-2493 2.14e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.21  E-value: 2.14e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2271 QEENKELTSQLEDARQLYHDSKNELTKLESELKSLKDQTTDLNNSLEKCKEHENNLEGIIKQQEADIQNCKFSCEQLETD 2350
Cdd:COG4942     19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE 98

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2351 LAASRELTSRLHDEI-NAKEQKIISLLSGKEEAIQLA-----VEELHQQHSKEIKELENLLSQEEEENVALEEENKRALE 2424
Cdd:COG4942     99 LEAQKEELAELLRALyRLGRQPPLALLLSPEDFLDAVrrlqyLKYLAPARREQAEELRADLAELAALRAELEAERAELEA 178

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1039751015 2425 KTNQLTEALEAIKKESFEQKAQLDSFVKSMSSLQDDRDRIVSDYRQLEERHLSAILEKDQLIQDAAAEN 2493
Cdd:COG4942    179 LLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAG 247
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 2195-2866 2.28e-03

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 44.06  E-value: 2.28e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2195 EAKKWERRFGdaiQTKEEEVRLKEENcIALKDQLRQMAIHMEELKITVSRLEH-----DKEIWESKAqtELQHHQKAYDK 2269
Cdd:pfam12128  242 EFTKLQQEFN---TLESAELRLSHLH-FGYKSDETLIASRQEERQETSAELNQllrtlDDQWKEKRD--ELNGELSAADA 315

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2270 LQEENKELTSQLEDARQLYHDSKNELTKLESE-LKSLKDQTTDLNNSLEKCKEHENNLEGIIKQQEADI-QNCKFSCEQL 2347
Cdd:pfam12128  316 AVAKDRSELEALEDQHGAFLDADIETAAADQEqLPSWQSELENLEERLKALTGKHQDVTAKYNRRRSKIkEQNNRDIAGI 395

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2348 ETDLAASRELTSRLHDEINAKEQKIISLLSGKEEAIQLAVEELHQQHSKEIKELENLLSQEEEENVAleeenkraLEKTN 2427
Cdd:pfam12128  396 KDKLAKIREARDRQLAVAEDDLQALESELREQLEAGKLEFNEEEYRLKSRLGELKLRLNQATATPEL--------LLQLE 467

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2428 QLTEALEAIKKESFEQKAQLDSFVKSMSSLQDDRDRIVSDYRQLEERHLSAILEKDQLIQDAAAENNKLKEEmrgLRSHM 2507
Cdd:pfam12128  468 NFDERIERAREEQEAANAEVERLQSELRQARKRRDQASEALRQASRRLEERQSALDELELQLFPQAGTLLHF---LRKEA 544

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2508 DDLNSENAKLDAELVQYRRDLN-EVIAIKDSQQKQL----LDAQLQQNKELRNECTKLEERLKGLEAEKQSLQMSSDALQ 2582
Cdd:pfam12128  545 PDWEQSIGKVISPELLHRTDLDpEVWDGSVGGELNLygvkLDLKRIDVPEWAASEEELRERLDKAEEALQSAREKQAAAE 624

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2583 KEKQGLSKEIKNLQTQLTALQeegtlgvyhAQLKAKEEELQRLNMALSSSQKRtadLEEELVCVQKEATRKVSEIEDQlK 2662
Cdd:pfam12128  625 EQLVQANGELEKASREETFAR---------TALKNARLDLRRLFDEKQSEKDK---KNKALAERKDSANERLNSLEAQ-L 691

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2663 KELKHLHHDAgimrnetetAEERVAELARDLVEMEQKLLTVTKENKDLMAQIQAfgrsmsSLQDSRDHATEELGDLKKKY 2742
Cdd:pfam12128  692 KQLDKKHQAW---------LEEQKEQKREARTEKQAYWQVVEGALDAQLALLKA------AIAARRSGAKAELKALETWY 756

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2743 DASLKELAQlkewqdssrEGDVLSQAAFPLSTSENVLSRLEKLNQQLTSKDEQLLH-LSSELESSHNQVQSISKAMTSLQ 2821
Cdd:pfam12128  757 KRDLASLGV---------DPDVIAKLKREIRTLERKIERIAVRRQEVLRYFDWYQEtWLQRRPRLATQLSNIERAISELQ 827

                          650       660       670       680
                   ....*....|....*....|....*....|....*....|....*
gi 1039751015 2822 NERDRLWSELEKFRKSEEGKQRAAAPSAASSPAEVQSLKKAMSSL 2866
Cdd:pfam12128  828 QQLARLIADTKLRRAKLEMERKASEKQQVRLSENLRGLRCEMSKL 872
PTZ00121 PTZ00121
MAEBL; Provisional
 1318-1777 2.38e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 43.98  E-value: 2.38e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1318 ASELAKKSEEVLLLQDQINEQGLEIqnlKAASVEAQAHTELLKQELESSQLKVAGLEHLKTLQPELDALHKHMGQKEEEV 1397
Cdd:PTZ00121  1317 ADEAKKKAEEAKKKADAAKKKAEEA---KKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKA 1393

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1398 NYLYGQLSEKEQTLTTVQTEMVEQERLIKALHTQLEMQAKEHEERLKQAQVEICELKKKPTELEEETNAKQQLQRKLQAA 1477
Cdd:PTZ00121  1394 DEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKAD 1473

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1478 LISRK-EALKENKSLQEQLSSARDAVERLTKSLADVESQVSVQNQEKDAVLGKLTILQEERdkliaemdrfllenqslsg 1556
Cdd:PTZ00121  1474 EAKKKaEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAK------------------- 1534

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1557 SCESLKLALGGLTEDKEKLMEELESVRSSKMAEstewqEKHKELQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQELY 1636
Cdd:PTZ00121  1535 KADEAKKAEEKKKADELKKAEELKKAEEKKKAE-----EAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKA 1609

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1637 AKLRSTESDKREREKQLQDAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEAQPVGGTGESMEAllssNSSLKEEL 1716
Cdd:PTZ00121  1610 EEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKA----EEAKKAEE 1685

                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1039751015 1717 EKITLEHKTLSKEFEALMAE---KDALSEETRNLKLQVEAQVLKQASLEATEKSDEPKDVIEEV 1777
Cdd:PTZ00121  1686 DEKKAAEALKKEAEEAKKAEelkKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEA 1749
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
2551-3036 2.61e-03

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 43.51  E-value: 2.61e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2551 KELRNECTKLEERLKGLEAEKQSLQMSSDALQKEKQGLSKEIKNLQTQLTALQEE-GTLGVYHAQLKAKEEELQRLNMAL 2629
Cdd:PRK03918   168 GEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREElEKLEKEVKELEELKEEIEELEKEL 247

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2630 SSSQKRTADLEEELVCVQKEATRKVSEIEDqLKKELKHLhhdagimrNETETAEERVAELARDLVEMEQKLLTVTKENKD 2709
Cdd:PRK03918   248 ESLEGSKRKLEEKIRELEERIEELKKEIEE-LEEKVKEL--------KELKEKAEEYIKLSEFYEEYLDELREIEKRLSR 318

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2710 LMAQIQAFGRSMSSLQDSRdhatEELGDLKKKYDASLKELAQLKEWQDSSREGDVLSQAAFPLSTSENVLSrLEKLNQQL 2789
Cdd:PRK03918   319 LEEEINGIEERIKELEEKE----ERLEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLT-PEKLEKEL 393

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2790 TSKDEQLLHLSSELESshnqvqsISKAMTSLQNERDRLWSELEKFRKSE--------EGKQRAAAPSAASSPAEVQSLKK 2861
Cdd:PRK03918   394 EELEKAKEEIEEEISK-------ITARIGELKKEIKELKKAIEELKKAKgkcpvcgrELTEEHRKELLEEYTAELKRIEK 466

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2862 AMSSLQNDRDRLLKELKNLQQQyLQMSQEMTELRPLKAQLQESQDQTKALQVME--------EELRQENLSWQHELRQLR 2933
Cdd:PRK03918   467 ELKEIEEKERKLRKELRELEKV-LKKESELIKLKELAEQLKELEEKLKKYNLEElekkaeeyEKLKEKLIKLKGEIKSLK 545

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2934 MEKNSWELHERRmKEQFLMAISDKDQQLGHLQSLLRELRSSSQAQI------LSTQYQR-----QASPETSASLDGSQKL 3002
Cdd:PRK03918   546 KELEKLEELKKK-LAELEKKLDELEEELAELLKELEELGFESVEELeerlkeLEPFYNEylelkDAEKELEREEKELKKL 624

                          490       500       510
                   ....*....|....*....|....*....|....
gi 1039751015 3003 VYETELLRTQLNDSLKEIHQKELRIQQLNSKFSQ 3036
Cdd:PRK03918   625 EEELDKAFEELAETEKRLEELRKELEELEKKYSE 658
PTZ00121 PTZ00121
MAEBL; Provisional
 2073-2796 2.61e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 43.98  E-value: 2.61e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2073 DDTQSEAARVLADNLKLKKELQSNKESIKSQIKQKDEDLlRRLEQ---AEEKHRKEKKNMQEklDALHREKAHVEETLAE 2149
Cdd:PTZ00121  1089 ADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDA-RKAEEarkAEDARKAEEARKAE--DAKRVEIARKAEDARK 1165

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2150 IQVSltRKDQEMKELQGsldstlAQLAAFTKSMSSLQDDRD-RVIDEAKKWERrfgdaIQTKEEEVRLKEENCIALKDQL 2228
Cdd:PTZ00121  1166 AEEA--RKAEDAKKAEA------ARKAEEVRKAEELRKAEDaRKAEAARKAEE-----ERKAEEARKAEDAKKAEAVKKA 1232

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2229 RQMAIHMEELKITVSRLEHDKEIWESKAQTELQHHQKAYDKLQEENK-ELTSQLEDARQLYHDSKNELTKLESELKSLKD 2307
Cdd:PTZ00121  1233 EEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKaDELKKAEEKKKADEAKKAEEKKKADEAKKKAE 1312

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2308 QTTDLNNSLEKCKEHENNLEGIIKQQEadiqnckfscEQLETDLAASRELTSRlHDEINAKEQKIISLLSGKEEAIQLAv 2387
Cdd:PTZ00121  1313 EAKKADEAKKKAEEAKKKADAAKKKAE----------EAKKAAEAAKAEAEAA-ADEAEAAEEKAEAAEKKKEEAKKKA- 1380

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2388 eELHQQHSKEIKELENLLSQEEEENVALEEENKRALEKtnqltEALEAIKKESFEQKAQLDSFVKSMSSLQDDRDRivsd 2467
Cdd:PTZ00121  1381 -DAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAK-----KKADEAKKKAEEKKKADEAKKKAEEAKKADEAK---- 1450

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2468 yRQLEERHLSAILEKDQLIQDAAAENNKLKEEMRglrshmddlNSENAKLDAELVQYRRDlneVIAIKDSQQKQLLDAQL 2547
Cdd:PTZ00121  1451 -KKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAK---------KADEAKKKAEEAKKKAD---EAKKAAEAKKKADEAKK 1517

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2548 QQNKELRNECTKLEERLKGLEAEKQSLQMSSDALQKEKQGLSKEIKNLQTQLTALQEEGTLGVYHAQL-----KAKEEEL 2622
Cdd:PTZ00121  1518 AEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEakkaeEARIEEV 1597

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2623 QRLNMALSSSQKRTADLEEElVCVQKEATRKVSEIE---DQLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQK 2699
Cdd:PTZ00121  1598 MKLYEEEKKMKAEEAKKAEE-AKIKAEELKKAEEEKkkvEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKK 1676

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2700 LLTVTKENKDLMAQIQAFGRSMSSLQDSRDHATEELGDLKKKYDASLKELAQLKEWQDSSREGDVLSQAAFPLSTSENVL 2779
Cdd:PTZ00121  1677 AEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEK 1756

                          730
                   ....*....|....*..
gi 1039751015 2780 SRLEKLNQQLTSKDEQL 2796
Cdd:PTZ00121  1757 KKIAHLKKEEEKKAEEI 1773
ClpA COG0542
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ...
 2559-2658 2.66e-03

ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440308 [Multi-domain]  Cd Length: 836  Bit Score: 43.53  E-value: 2.66e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2559 KLEERLKGLEAEKQSLQMSSDALQKEK-QGLSKEIKNLQTQLTAL----QEEGTLgvyHAQLKAKEEELQRLNMALSSSQ 2633
Cdd:COG0542    415 ELERRLEQLEIEKEALKKEQDEASFERlAELRDELAELEEELEALkarwEAEKEL---IEEIQELKEELEQRYGKIPELE 491

                           90       100
                   ....*....|....*....|....*
gi 1039751015 2634 KRTADLEEELVCVQKEATRKVSEIE 2658
Cdd:COG0542    492 KELAELEEELAELAPLLREEVTEED 516
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 1421-2009 2.83e-03

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 43.56  E-value: 2.83e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1421 QERLIKALHTQLEMQAKEHEERLKQAQVEicelkkkpTELEEETNAKQqlqRKLQAALISRKEALKENKSLQEQLSSARD 1500
Cdd:pfam05483  200 EELRVQAENARLEMHFKLKEDHEKIQHLE--------EEYKKEINDKE---KQVSLLLIQITEKENKMKDLTFLLEESRD 268

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1501 AVERLtksladvESQVSVQNQEKDAVLGKLTILQEERDKLIAEMDRFLLENQSLSGSCESLKLALGGLTEDKEKLMEELE 1580
Cdd:pfam05483  269 KANQL-------EEKTKLQDENLKELIEKKDHLTKELEDIKMSLQRSMSTQKALEEDLQIATKTICQLTEEKEAQMEELN 341

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1581 SVRSSKMAESTEWQEKHKELQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQELYAKLRSTESDKREREKQL---QDAE 1657
Cdd:pfam05483  342 KAKAAHSFVVTEFEATTCSLEELLRTEQQRLEKNEDQLKIITMELQKKSSELEEMTKFKNNKEVELEELKKILaedEKLL 421

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1658 QEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEAQPVGGTGESMEALLSSNSSLKEELEKITLEHKTLSKEFEALMAEK 1737
Cdd:pfam05483  422 DEKKQFEKIAEELKGKEQELIFLLQAREKEIHDLEIQLTAIKTSEEHYLKEVEDLKTELEKEKLKNIELTAHCDKLLLEN 501

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1738 DALSEETRNLKLQVEAQvlkqasleateksdePKDVIEevtqavvGKSQERDALSDSAKLEDSEAILMgDGAKPGVSETF 1817
Cdd:pfam05483  502 KELTQEASDMTLELKKH---------------QEDIIN-------CKKQEERMLKQIENLEEKEMNLR-DELESVREEFI 558

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1818 SSHDDIKNylqQLDQLKGRIAELEMEKQKDRELSQALENEKNALLTQISAKDSELKLLEEE----VTKRTTLNQQIQEEL 1893
Cdd:pfam05483  559 QKGDEVKC---KLDKSEENARSIEYEVLKKEKQMKILENKCNNLKKQIENKNKNIEELHQEnkalKKKGSAENKQLNAYE 635

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1894 CRVTKLKETAEEEKDDLEErlmnqlaelngSIGNYYQDVTDAQIKNEQLESEMrnlqrcvseleEEKQQLVKEKTKVESE 1973
Cdd:pfam05483  636 IKVNKLELELASAKQKFEE-----------IIDNYQKEIEDKKISEEKLLEEV-----------EKAKAIADEAVKLQKE 693

                          570       580       590
                   ....*....|....*....|....*....|....*.
gi 1039751015 1974 IRKEYMEKIqgAQKGPANKSHAKELQELLREKQQEV 2009
Cdd:pfam05483  694 IDKRCQHKI--AEMVALMEKHKHQYDKIIEERDSEL 727
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1999-2215 3.00e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.83  E-value: 3.00e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1999 QELLREKQQEVKQLQKdciryleRISALEKTVKALEFVHTESQKDLDVTKGNLAQAVEHRKKAQAELSSFKILLDDTQSE 2078
Cdd:COG4942     19 ADAAAEAEAELEQLQQ-------EIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKE 91

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2079 AARVLADNLKLKKELqsnKESIKSQIKQKDEDLLRRLEQAEEKHRKEKknMQEKLDALHREKAHVEETLAEIQVSLTRKD 2158
Cdd:COG4942     92 IAELRAELEAQKEEL---AELLRALYRLGRQPPLALLLSPEDFLDAVR--RLQYLKYLAPARREQAEELRADLAELAALR 166

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1039751015 2159 QEMKELQGSLDSTLAQLAAFTKSMSSLQDDRDRVIDEAKKWERRFGDAIQTKEEEVR 2215
Cdd:COG4942    167 AELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAE 223
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
169-380 3.05e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 43.37  E-value: 3.05e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  169 LDQSEQASQLDKSSAEMEDFVLMKQQLQEKEELISTLQ--TQLSQTQAEQAAQLSSMQQVV--------REKDARFETQV 238
Cdd:COG4913    218 LEEPDTFEAADALVEHFDDLERAHEALEDAREQIELLEpiRELAERYAAARERLAELEYLRaalrlwfaQRRLELLEAEL 297

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  239 RLHEDELLQLVTQsdvETEMQQKLRVMQRKLEEHEEALLGR-AQVVDLLQKELTSAEQRNQVLSQQLQLLEAEHNTLKNT 317
Cdd:COG4913    298 EELRAELARLEAE---LERLEARLDALREELDELEAQIRGNgGDRLEQLEREIERLERELEERERRRARLEALLAALGLP 374

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1039751015  318 METERQESKTLMEKVELEVAERKLSFHNLQEEMHQLQGQLERAGQAQADLETQYSALQQRHKT 380
Cdd:COG4913    375 LPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSN 437
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 885-1136 3.56e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.83  E-value: 3.56e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  885 EKQKDVETLQQTIQEKDQQVTelsfsmtekmvQLNEEKFSLGVEIKTLKEQLNLLSRTEEATKEQVEESGAgsslKLGHD 964
Cdd:COG4942     24 EAEAELEQLQQEIAELEKELA-----------ALKKEEKALLKQLAALERRIAALARRIRALEQELAALEA----ELAEL 88

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  965 ESGQEGLQQELELLRKESEQRKRKLQAALINRKELLQKVSQLEEELAKVREDSRKEIPFGENERRKLEEDREnrddpeew 1044
Cdd:COG4942     89 EKEIAELRAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLA-------- 160

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1045 gtsKWREVEASLKQTISEKEVELEGIRRDLKEKTAAEEELQAVVQRMTRDLQSKTKQIDLLQEEVTENQATIQKLVTGTM 1124
Cdd:COG4942    161 ---ELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAA 237

                          250
                   ....*....|..
gi 1039751015 1125 DAGNGGSAAPVK 1136
Cdd:COG4942    238 AAAERTPAAGFA 249
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 2191-2922 3.86e-03

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 43.11  E-value: 3.86e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2191 RVIDEAKKWERRFGDAIQTKEEEVRLKE---ENCIALKDQLRQMAIHMEELKITVSRLEHD--------KEIWESKAQT- 2258
Cdd:TIGR00606  186 KALETLRQVRQTQGQKVQEHQMELKYLKqykEKACEIRDQITSKEAQLESSREIVKSYENEldplknrlKEIEHNLSKIm 265

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2259 ELQHHQKAYDKLQEENKELTSQLEDAR-QLYHDSKNELTKLE----SELKSLKDQTTDLNNSLEKckeheNNLEGIIKQQ 2333
Cdd:TIGR00606  266 KLDNEIKALKSRKKQMEKDNSELELKMeKVFQGTDEQLNDLYhnhqRTVREKERELVDCQRELEK-----LNKERRLLNQ 340

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2334 EADIQNCKFSCEQLETDLAASRELTSRLHDEINAKEQKIISLLSGKEEAIQL--AVEELHQQHSKEIKELENLLSQEEEE 2411
Cdd:TIGR00606  341 EKTELLVEQGRLQLQADRHQEHIRARDSLIQSLATRLELDGFERGPFSERQIknFHTLVIERQEDEAKTAAQLCADLQSK 420

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2412 NVALEEENKRALEKTNQLTEALEAIKKESFEQKAQLDSFVKSMSSLQDDRDRIVSDYRQL--EERHLSaILEKDQLIQDA 2489
Cdd:TIGR00606  421 ERLKQEQADEIRDEKKGLGRTIELKKEILEKKQEELKFVIKELQQLEGSSDRILELDQELrkAERELS-KAEKNSLTETL 499

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2490 AAENNKLKEEMRGLRSHMDDLNSENAKLDAE---------LVQYRRDLNEVIAIKDSQQKQLLDAQL---QQNKELRNEC 2557
Cdd:TIGR00606  500 KKEVKSLQNEKADLDRKLRKLDQEMEQLNHHtttrtqmemLTKDKMDKDEQIRKIKSRHSDELTSLLgyfPNKKQLEDWL 579

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2558 TKLEERLKGLEAEKQSLQMSSDALQKEKQGLSKEIKNLQTQLTALqEEGTLGVYHAQlkAKEEELQRLNMALSSSQKRTA 2637
Cdd:TIGR00606  580 HSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSY-EDKLFDVCGSQ--DEESDLERLKEEIEKSSKQRA 656

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2638 DLEEElvcvqkeatrkvSEIEDQLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLTVTKENKDLMAQIQAF 2717
Cdd:TIGR00606  657 MLAGA------------TAVYSQFITQLTDENQSCCPVCQRVFQTEAELQEFISDLQSKLRLAPDKLKSTESELKKKEKR 724

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2718 GRSMSSLQDSR----DHATEELGDLKKKYDASLKELAQLKewQDSSREGDVLSQAAFPLSTSENVLSR---LEKLNQQLT 2790
Cdd:TIGR00606  725 RDEMLGLAPGRqsiiDLKEKEIPELRNKLQKVNRDIQRLK--NDIEEQETLLGTIMPEEESAKVCLTDvtiMERFQMELK 802

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2791 SKDEQLLHLSSELESS--HNQVQSISKAMTSLQNERDRLWSELEKFRKSEEGKQRaaapsaasspaEVQSLKKAMSSLQN 2868
Cdd:TIGR00606  803 DVERKIAQQAAKLQGSdlDRTVQQVNQEKQEKQHELDTVVSKIELNRKLIQDQQE-----------QIQHLKSKTNELKS 871

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1039751015 2869 DRDRLLKELKNLQQQYLQMSQEMTELRPLKAQLQESQDQTKALQVMEEELRQEN 2922
Cdd:TIGR00606  872 EKLQIGTNLQRRQQFEEQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEK 925
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
83-525 3.88e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 42.83  E-value: 3.88e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015   83 EALQEEKKAAENKIKKIKLHAKAKIMSLNKHMEEIKTQGGAAlppEAQAEELSKHNKSSTEEEMEIEKIKHELQEKEKLI 162
Cdd:COG4717     49 ERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEY---AELQEELEELEEELEELEAELEELREELEKLEKLL 125

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  163 SSLQAQLDQSEQASQLDKSSAEMEDFVLMKQQLQEKEELISTLQTQLSQTQAEQAAQLSSMQQVVREKDARFETQVRLHE 242
Cdd:COG4717    126 QLLPLYQELEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQ 205

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  243 DELLQLVTQSDV-------------ETEMQQKLRVMQRKLEEHEEALLGRAQVVDLLQKELTSAEQRNQVLSQQLQLLEA 309
Cdd:COG4717    206 QRLAELEEELEEaqeeleeleeeleQLENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGL 285

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  310 EHnTLKNTMETERQESKTLMEKVELEVAERKLSFHNLQEEMHQLQGQLERAGQAQADLETQYSALQQRH-KTEMEEKTAC 388
Cdd:COG4717    286 LA-LLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLrEAEELEEELQ 364

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  389 ILSLQKNEQELQSACAALKEENSKLLQEKHDQAAESAQAMRQLEDQLQQKSKEISQFVNKPNLQKNETASQtslpdvNNE 468
Cdd:COG4717    365 LEELEQEIAALLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEELEEELE------ELE 438

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1039751015  469 GDQAVMEETVASLQKRVVELENEKGALLlSSGELEELKAENEKLSSRITLLEAQNRA 525
Cdd:COG4717    439 EELEELEEELEELREELAELEAELEQLE-EDGELAELLQELEELKAELRELAEEWAA 494
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 2210-2754 3.94e-03

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 43.24  E-value: 3.94e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2210 KEEEVRLKEENCIALKDQLRQMAIHMEELKITVSRLEHDKEIWESKAQTELQhhqkaydkLQEENKELTSQLEDARQLYH 2289
Cdd:pfam01576    3 QEEEMQAKEEELQKVKERQQKAESELKELEKKHQQLCEEKNALQEQLQAETE--------LCAEAEEMRARLAARKQELE 74

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2290 DSkneLTKLESELKSLKDQTTDLNNSLEKCKEHENNLEGIIKQQEADIQ-------NCKFSCEQLETDLAASRELTSRLH 2362
Cdd:pfam01576   75 EI---LHELESRLEEEEERSQQLQNEKKKMQQHIQDLEEQLDEEEAARQklqlekvTTEAKIKKLEEDILLLEDQNSKLS 151

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2363 DEINAKEQKIISLLS--GKEEAIQLAVEELHQQHSKEIKELENLLSQEEEENVALEEENKRALEKTNQLTEALEAIKKES 2440
Cdd:pfam01576  152 KERKLLEERISEFTSnlAEEEEKAKSLSKLKNKHEAMISDLEERLKKEEKGRQELEKAKRKLEGESTDLQEQIAELQAQI 231

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2441 FEQKAQLDSFVKSMSSLQDDRDRIVSDYRQLEERHLSAILEKDQLIQDAAAE----------NNKLKEEMRGLRSHMDD- 2509
Cdd:pfam01576  232 AELRAQLAKKEEELQAALARLEEETAQKNNALKKIRELEAQISELQEDLESEraarnkaekqRRDLGEELEALKTELEDt 311

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2510 LNSENA------KLDAELVQYRRDLNEVIAIKDSQQKQLLDAQLQQNKElrnectkLEERLKGLEAEKQSLQMSSDALQK 2583
Cdd:pfam01576  312 LDTTAAqqelrsKREQEVTELKKALEEETRSHEAQLQEMRQKHTQALEE-------LTEQLEQAKRNKANLEKAKQALES 384

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2584 EKQGLSKEIKNLQTqltalqeeGTLGVYHAQLKAkEEELQRLNMALSSSQKRTADLEEELVCVQKEaTRKVSEIEDQLKK 2663
Cdd:pfam01576  385 ENAELQAELRTLQQ--------AKQDSEHKRKKL-EGQLQELQARLSESERQRAELAEKLSKLQSE-LESVSSLLNEAEG 454

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2664 ELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLTVTKENKDLMAQIQAFGRSMSSLQDSRDHATEELGDLKKKYD 2743
Cdd:pfam01576  455 KNIKLSKDVSSLESQLQDTQELLQEETRQKLNLSTRLRQLEDERNSLQEQLEEEEEAKRNVERQLSTLQAQLSDMKKKLE 534

                          570
                   ....*....|.
gi 1039751015 2744 ASLKELAQLKE 2754
Cdd:pfam01576  535 EDAGTLEALEE 545
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
2051-2689 4.02e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 42.98  E-value: 4.02e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2051 LAQAVEH---RKKAQAELSSFKILLDDTQSEAARVLADNLK-----LKKELQSNKESIkSQIKQKDEDLLRRLEQAEEKH 2122
Cdd:COG4913    254 LEPIRELaerYAAARERLAELEYLRAALRLWFAQRRLELLEaeleeLRAELARLEAEL-ERLEARLDALREELDELEAQI 332

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2123 R----KEKKNMQEKLDALHREKAHVEETLAEIQVSLTRKDQEMKELQGSLDSTLAQLAAFTKSMSSLQDDRDRVIDEAKK 2198
Cdd:COG4913    333 RgnggDRLEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEA 412

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2199 WERRFGDAIQTKEEEVR-LKE------ENCIALKDQLRqmaihmEELKITVSRL---------EHDKEIWESKAQTELqh 2262
Cdd:COG4913    413 ALRDLRRELRELEAEIAsLERrksnipARLLALRDALA------EALGLDEAELpfvgelievRPEEERWRGAIERVL-- 484

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2263 HQKAYDKLQEENkeltsQLEDARQLYHDSKNELT----KLESELKSLKDQTTDLNNSLEKCKEHENNLEGIIKQQEADIQ 2338
Cdd:COG4913    485 GGFALTLLVPPE-----HYAAALRWVNRLHLRGRlvyeRVRTGLPDPERPRLDPDSLAGKLDFKPHPFRAWLEAELGRRF 559

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2339 N--CKFSCEQLE-TDLAASRE-LTSRLHD--EINAKEQKIISLLSGKEEAIQLAVEElhqqhsKEIKELEnllsqeeeen 2412
Cdd:COG4913    560 DyvCVDSPEELRrHPRAITRAgQVKGNGTrhEKDDRRRIRSRYVLGFDNRAKLAALE------AELAELE---------- 623

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2413 valeeenkRALEKTNQLTEALEAIKKESFEQKAQLdSFVKSMSSLQDDRDRIVSDYRQLEERhLSAILEKDQLIQDAAAE 2492
Cdd:COG4913    624 --------EELAEAEERLEALEAELDALQERREAL-QRLAEYSWDEIDVASAEREIAELEAE-LERLDASSDDLAALEEQ 693

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2493 NNKLKEEMRGLRSHMDDLNSENAKLDAELVQYRRDLNEViaikdsqQKQLLDAQLQQNKELRnecTKLEERLKGLEAEKQ 2572
Cdd:COG4913    694 LEELEAELEELEEELDELKGEIGRLEKELEQAEEELDEL-------QDRLEAAEDLARLELR---ALLEERFAAALGDAV 763

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2573 SLQMsSDALQKEKQGLSKEIKNLQTQLTALQEEgtlgvYHAQLKAKEEELQRLNMALSSSQKRTADLEEElvcvqkEATR 2652
Cdd:COG4913    764 EREL-RENLEERIDALRARLNRAEEELERAMRA-----FNREWPAETADLDADLESLPEYLALLDRLEED------GLPE 831

                          650       660       670       680
                   ....*....|....*....|....*....|....*....|.
gi 1039751015 2653 KVSEIEDQLKK----ELKHLHHDagiMRNETETAEERVAEL 2689
Cdd:COG4913    832 YEERFKELLNEnsieFVADLLSK---LRRAIREIKERIDPL 869
46 PHA02562
endonuclease subunit; Provisional
 2444-2669 4.46e-03

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 42.69  E-value: 4.46e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2444 KAQLDSFVKSMSSLQDDRDRIVSDYRQLEERHLSAILEKDQLIQDAAAENNKLKEEMRGLRSHMDDLNSENAKLDAELVQ 2523
Cdd:PHA02562   194 QQQIKTYNKNIEEQRKKNGENIARKQNKYDELVEEAKTIKAEIEELTDELLNLVMDIEDPSAALNKLNTAAAKIKSKIEQ 273

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2524 YRRDlneviaIKDSQQKQLLDAQLQQNKELRNECTKLEERLKGLEaekQSLQMSSDALQKEKQ------GLSKEIKNLQT 2597
Cdd:PHA02562   274 FQKV------IKMYEKGGVCPTCTQQISEGPDRITKIKDKLKELQ---HSLEKLDTAIDELEEimdefnEQSKKLLELKN 344

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1039751015 2598 QLTalQEEGTLGVYHAQLKAKEEELQRLnmalsssQKRTADLEEELVCVQKEATRKVSEIEDqLKKELKHLH 2669
Cdd:PHA02562   345 KIS--TNKQSLITLVDKAKKVKAAIEEL-------QAEFVDNAEELAKLQDELDKIVKTKSE-LVKEKYHRG 406
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2529-2761 4.66e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.44  E-value: 4.66e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2529 NEVIAIKDSQQKQLLDAQLQQNKELRnectKLEERLKGLEAEKQSLQMSSDALQKEKQGLSKEIKNLQTQLTALQEEgtL 2608
Cdd:COG4942     19 ADAAAEAEAELEQLQQEIAELEKELA----ALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKE--I 92

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2609 GVYHAQLKAKEEELQRLnmaLSSSQKRTADLEEELVCVQKEATRKVSEIEDqLKKELKHLHHDAGIMRNETETAEERVAE 2688
Cdd:COG4942     93 AELRAELEAQKEELAEL---LRALYRLGRQPPLALLLSPEDFLDAVRRLQY-LKYLAPARREQAEELRADLAELAALRAE 168

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1039751015 2689 LARDLVEMEQKLLTVTKENKDLMAQIQAFGRSMSSLQDSRDHATEELGDLKKKYDASLKELAQLKEWQDSSRE 2761
Cdd:COG4942    169 LEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAE 241
PRK12704 PRK12704
phosphodiesterase; Provisional
 2057-2219 4.99e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 42.46  E-value: 4.99e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2057 HRKKAQAELSSFKILLDDTQsEAARVLADNLKLKKELQSNKESIKSQIKQKDEDLLRR--LEQAEEKHRKEKKNMQEKLD 2134
Cdd:PRK12704    25 RKKIAEAKIKEAEEEAKRIL-EEAKKEAEAIKKEALLEAKEEIHKLRNEFEKELRERRneLQKLEKRLLQKEENLDRKLE 103

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2135 ALHREKAHVEETLAEI---QVSLTRKDQEMKELQGSLDSTLAQLAAFTKsmsslQDDRDRVIDEAKKwERRFGDAIQTKE 2211
Cdd:PRK12704   104 LLEKREEELEKKEKELeqkQQELEKKEEELEELIEEQLQELERISGLTA-----EEAKEILLEKVEE-EARHEAAVLIKE 177


                   ....*...
gi 1039751015 2212 EEVRLKEE 2219
Cdd:PRK12704   178 IEEEAKEE 185
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 2002-2215 5.09e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 42.12  E-value: 5.09e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2002 LREKQQEVKQLQKDCIRYLERISALEKTVKALEFVHTESQKDLDVTKGNLAQAVEHRKKAQAELSSFKILLDDTQSEAAR 2081
Cdd:COG3883     18 IQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARALYR 97

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2082 VLADNLKLKKELQS-------NKESIKSQIKQKDEDLLRRLEQAEEKHRKEKKNMQEKLDALHREKAHVEETLAEIQVSL 2154
Cdd:COG3883     98 SGGSVSYLDVLLGSesfsdflDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAELEAQQ 177

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1039751015 2155 TRKDQEMKELQGSLDSTLAQLAAFTKSMSSLQDDRDRVIDEAKKWERRFGDAIQTKEEEVR 2215
Cdd:COG3883    178 AEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAAAA 238
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
2543-2974 5.39e-03

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 42.74  E-value: 5.39e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2543 LDAQLQQNKELRNECTKLEERLKGLEAEKQSLQMSSDALQKEKQGLSKEIKNLQTQLTALQE-----------EGTLGVY 2611
Cdd:PRK03918   226 LEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKElkekaeeyiklSEFYEEY 305

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2612 HAQLKAKEEELQRLNMALSSSQKRTADLE------EELVCVQKEATRKVSEIEDQLKKELKHLHHDAGIMRNETETAEER 2685
Cdd:PRK03918   306 LDELREIEKRLSRLEEEINGIEERIKELEekeerlEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLT 385

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2686 VAELARDLVEMEQKLLTVTKENKDLMAQIQAFGRSMSSLQDS---------------RDHATEELGDLKKKYDASLKELA 2750
Cdd:PRK03918   386 PEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAieelkkakgkcpvcgRELTEEHRKELLEEYTAELKRIE 465

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2751 -QLKEWQDSSREGDVLSQAAFPLSTSENVLSRLEKLNQQLTSKDEQLLHLSSE-LESSHNQVQSISKAMTSLQNERDRLW 2828
Cdd:PRK03918   466 kELKEIEEKERKLRKELRELEKVLKKESELIKLKELAEQLKELEEKLKKYNLEeLEKKAEEYEKLKEKLIKLKGEIKSLK 545

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2829 SELEKFrKSEEGKQRAAAPSAASSPAEVQSLKKAMSSL----QNDRDRLLKELKNLQQQYLQMSQEMTELRPLKAQLQES 2904
Cdd:PRK03918   546 KELEKL-EELKKKLAELEKKLDELEEELAELLKELEELgfesVEELEERLKELEPFYNEYLELKDAEKELEREEKELKKL 624

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1039751015 2905 QDQTKALQVMEEELRQENLSWQHELRQLRMEKNSWELHE-RRMKEQFLMAISDKDQQLGHLQSLLRELRSS 2974
Cdd:PRK03918   625 EEELDKAFEELAETEKRLEELRKELEELEKKYSEEEYEElREEYLELSRELAGLRAELEELEKRREEIKKT 695
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 860-1083 5.50e-03

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 42.42  E-value: 5.50e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  860 QEMEGLSQALSQKELEIAKMDQLLLE--KQKDVETLQQTIQEKDQQVTElSFSMTEKMVQLNEEKFSLGVEIKTLKEQLN 937
Cdd:pfam17380  348 RELERIRQEERKRELERIRQEEIAMEisRMRELERLQMERQQKNERVRQ-ELEAARKVKILEEERQRKIQQQKVEMEQIR 426

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  938 llSRTEEATKEQVEESGAGSSLKLGHDESGQEGLQQELELLRKESEQRKRKLQAALINRKELLQKVSQLEEELAKVREDS 1017
Cdd:pfam17380  427 --AEQEEARQREVRRLEEERAREMERVRLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRRKILEKELEER 504

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1039751015 1018 RKEIPFGENERRKLEEDRENRDdpeewgTSKWREVEASLKQTISEKEVELEGIRRDLKEKTAAEEE 1083
Cdd:pfam17380  505 KQAMIEEERKRKLLEKEMEERQ------KAIYEEERRREAEEERRKQQEMEERRRIQEQMRKATEE 564
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 760-992 5.73e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.06  E-value: 5.73e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  760 LAELRARVQELESSLAEAEKQRgldyESQRAQHNLLTEQIHSLSIEAKSKDVKIEALQRELDGVQlqfceqgTQMKTLQS 839
Cdd:COG4942     29 LEQLQQEIAELEKELAALKKEE----KALLKQLAALERRIAALARRIRALEQELAALEAELAELE-------KEIAELRA 97

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  840 QLEAKEREVRE---GTERLRDISQEMEGLSQA-LSQKELEIAKMDQLLLEKQKDVETLQQTIQEKDQQVTELSFSMTEKM 915
Cdd:COG4942     98 ELEAQKEELAEllrALYRLGRQPPLALLLSPEdFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELE 177

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  916 VQLNE---EKFSLGVEIKTLKEQLNLLSRTEEATKEQVEESgagsslklghdESGQEGLQQELELLRKESEQRKRKLQAA 992
Cdd:COG4942    178 ALLAEleeERAALEALKAERQKLLARLEKELAELAAELAEL-----------QQEAEELEALIARLEAEAAAAAERTPAA 246
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1432-1622 6.63e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 42.31  E-value: 6.63e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1432 LEMQAKEHEERLKQAQVEICELKKK------PTELEEETNAKQQLQRKLQAALISRKEALKENKSLQEQLSSARDAVERL 1505
Cdd:COG3206    180 LEEQLPELRKELEEAEAALEEFRQKnglvdlSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLGSGPDALPEL 259

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1506 TKS--LADVESQVSVQNQEKDAVLGKLT-------ILQEERDKLIAEMdrflleNQSLSGSCESLKLALGGLTEDKEKLM 1576
Cdd:COG3206    260 LQSpvIQQLRAQLAELEAELAELSARYTpnhpdviALRAQIAALRAQL------QQEAQRILASLEAELEALQAREASLQ 333

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*.
gi 1039751015 1577 EELESVRSsKMAESTEWQEKHKELQKEYEVLLQSYENVSNEAERIQ 1622
Cdd:COG3206    334 AQLAQLEA-RLAELPELEAELRRLEREVEVARELYESLLQRLEEAR 378
46 PHA02562
endonuclease subunit; Provisional
 1824-2014 6.83e-03

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 41.92  E-value: 6.83e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1824 KNYLQQLDQLKG-RIAELEMEKQKDRELSQALENEKNALLTQISAKDSELKLLEEEVTKRTTLNQQIQEELCRVTKLKET 1902
Cdd:PHA02562   201 NKNIEEQRKKNGeNIARKQNKYDELVEEAKTIKAEIEELTDELLNLVMDIEDPSAALNKLNTAAAKIKSKIEQFQKVIKM 280

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1903 AEE------------EKDDLEERLMNQLAELNGSignyYQDVTDAQIKNEQLESEMRNLQRCVSEL----EEEKQQL--- 1963
Cdd:PHA02562   281 YEKggvcptctqqisEGPDRITKIKDKLKELQHS----LEKLDTAIDELEEIMDEFNEQSKKLLELknkiSTNKQSLitl 356

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1039751015 1964 VKEKTKVESEIRKeymekiqgAQKGPANksHAKELQELLREKQQEVKQLQK 2014
Cdd:PHA02562   357 VDKAKKVKAAIEE--------LQAEFVD--NAEELAKLQDELDKIVKTKSE 397
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1155-1631 7.10e-03

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 42.31  E-value: 7.10e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1155 ELEGRILDLEKDKTQLQK---KLQEALIARKAILKKAQEKEKQLKEELREQKDAYHHLQGQFHEQNKEKENIADQLRQLQ 1231
Cdd:TIGR04523  215 SLESQISELKKQNNQLKDnieKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLK 294

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1232 CQAREsidrqlpgtgqqepgppapsLEGISLEDTEPASESDLHAAQPS-PPGETAALQATVSVAQIQAQLKEMEVEKEEL 1310
Cdd:TIGR04523  295 SEISD--------------------LNNQKEQDWNKELKSELKNQEKKlEEIQNQISQNNKIISQLNEQISQLKKELTNS 354

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1311 ELKVSSIASELAKKSEEVLLLQDQINEQGLEIQNLKAASVEAQahTELLKQELESSQLKvaglEHLKTLQPELDALHKHM 1390
Cdd:TIGR04523  355 ESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLE--SKIQNQEKLNQQKD----EQIKKLQQEKELLEKEI 428

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1391 GQKEEEVNYLYGQLSEKEQTLTTVQTEMVEQERLIKALHTQLEMQAKEHEERLKQAQVEICELKKKPTELEEETNAKQQL 1470
Cdd:TIGR04523  429 ERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKEL 508

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1471 QrklqaalisrkealKENKSLQEQLSSARDAVERLTKSLADVESQVSVQNQEKDAVLGKLT--ILQEERDKLIAEMDRFL 1548
Cdd:TIGR04523  509 E--------------EKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDFELKkeNLEKEIDEKNKEIEELK 574

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1549 LENQSLSGSCESLKLALGGLTEDKEKLMEELEsvrsSKMAESTEWQEKHKELQKEYEVLLQSYENVSNEAERIQHVVESV 1628
Cdd:TIGR04523  575 QTQKSLKKKQEEKQELIDQKEKEKKDLIKEIE----EKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQI 650


                   ...
gi 1039751015 1629 RQE 1631
Cdd:TIGR04523  651 KET 653
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 46-402 7.12e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 42.36  E-value: 7.12e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015   46 MESTQEDALHRLAEAEKLVVELKDIIS---QKDVQLQQKDEALQEEKKAAENKIKKIKlhakAKIMSLNKHMEEIKTQGg 122
Cdd:TIGR02169  686 LKRELSSLQSELRRIENRLDELSQELSdasRKIGEIEKEIEQLEQEEEKLKERLEELE----EDLSSLEQEIENVKSEL- 760

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  123 AALPPEAQAEELSKHNKSSTEEEMEIEKIKHELQEKEKLISSLQAQLdqSEQASQLDKSSAEMEDFVLMKQQLQEKEELI 202
Cdd:TIGR02169  761 KELEARIEELEEDLHKLEEALNDLEARLSHSRIPEIQAELSKLEEEV--SRIEARLREIEQKLNRLTLEKEYLEKEIQEL 838

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  203 STLQTQLSQTQAEQAAQLSSMQQVVREKDARFE---TQVRLHEDELLQLVTQSDvetEMQQKLRVMQRKLEEHEEALLGR 279
Cdd:TIGR02169  839 QEQRIDLKEQIKSIEKEIENLNGKKEELEEELEeleAALRDLESRLGDLKKERD---ELEAQLRELERKIEELEAQIEKK 915

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  280 AQVVDLLQKELTSAEQRNqvlsqqlqlleAEHNTLKNTMETERQESKTLmEKVELEVAErklsfhnLQEEMHQLQGQLER 359
Cdd:TIGR02169  916 RKRLSELKAKLEALEEEL-----------SEIEDPKGEDEEIPEEELSL-EDVQAELQR-------VEEEIRALEPVNML 976

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|...
gi 1039751015  360 AGQAQADLETQYSALQQRHKTEMEEKTACILSLQKNEQELQSA 402
Cdd:TIGR02169  977 AIQEYEEVLKRLDELKEKRAKLEEERKAILERIEEYEKKKREV 1019
Crescentin pfam19220
Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament ...
 686-879 7.72e-03

Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament proteins, named crescentin, whose cytoskeletal function is required for the vibrioid and helical shapes of Caulobacter crescentus. Without crescentin, the cells adopt a straight-rod morphology. Crescentin has characteriztic features of IF proteins including the ability to assemble into filaments in vitro without energy or cofactor requirements. In vivo, crescentin forms a helical structure that colocalizes with the inner cell curvatures beneath the cytoplasmic membrane.


Pssm-ID: 437057 [Multi-domain]  Cd Length: 401  Bit Score: 41.59  E-value: 7.72e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  686 ELERLKTQVLELETSLHTAEETYkRNLSEKVKEISS-LTQLSEEVKESAEEARSTLAAVTEERdqllyqvkelDVLAELR 764
Cdd:pfam19220   42 ELPQAKSRLLELEALLAQERAAY-GKLRRELAGLTRrLSAAEGELEELVARLAKLEAALREAE----------AAKEELR 110

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  765 ARVQELESSLAEAEKQrgLDYESQRAQHnlLTEQIHSLSIEAKSKDVKIEALQRELDGVQLQFCEQGTQMKTLQSQLEAK 844
Cdd:pfam19220  111 IELRDKTAQAEALERQ--LAAETEQNRA--LEEENKALREEAQAAEKALQRAEGELATARERLALLEQENRRLQALSEEQ 186

                          170       180       190
                   ....*....|....*....|....*....|....*
gi 1039751015  845 EREVREGTERLRDISQEMEGLSQALSQKELEIAKM 879
Cdd:pfam19220  187 AAELAELTRRLAELETQLDATRARLRALEGQLAAE 221
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2579-2836 7.75e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 41.67  E-value: 7.75e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2579 DALQKEKQGLSKEIKNLQTQLTALQeegtlgvyhAQLKAKEEELQRLNMALSSSQKRTADLEEELvcvqKEATRKVSEIE 2658
Cdd:COG4942     23 AEAEAELEQLQQEIAELEKELAALK---------KEEKALLKQLAALERRIAALARRIRALEQEL----AALEAELAELE 89

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2659 DQLKKelkhlhhdagiMRNETETAEERVAELARDLVEMEQKLLTVTKENKDLMAQIQAFGRSMSSLQDSRDHATEELGDL 2738
Cdd:COG4942     90 KEIAE-----------LRAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRAD 158

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2739 KKKYDASLKELAQLKEWQDSSREgdvlsqaafplstseNVLSRLEKLNQQLTSKDEQLLHLSSELESSHNQVQSISKAMT 2818
Cdd:COG4942    159 LAELAALRAELEAERAELEALLA---------------ELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAE 223

                          250
                   ....*....|....*...
gi 1039751015 2819 SLQNERDRLWSELEKFRK 2836
Cdd:COG4942    224 ELEALIARLEAEAAAAAE 241
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1343-1525 8.06e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 41.93  E-value: 8.06e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1343 QNLKAASVEAQAHTELLKQELESSQLKVAGLEH-LKTLQPELDALhkhmgQKEEEVNYLYGQLSEKEQTLTTVQTEMVEQ 1421
Cdd:COG3206    164 QNLELRREEARKALEFLEEQLPELRKELEEAEAaLEEFRQKNGLV-----DLSEEAKLLLQQLSELESQLAEARAELAEA 238

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1422 ERLIKALHTQLEMQA------------KEHEERLKQAQVEICELKKKPTE--------LEEETNAKQQLQRKLQAALISR 1481
Cdd:COG3206    239 EARLAALRAQLGSGPdalpellqspviQQLRAQLAELEAELAELSARYTPnhpdvialRAQIAALRAQLQQEAQRILASL 318

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....
gi 1039751015 1482 KEALKENKSLQEQLSSARDAVERLTKSLADVESQVSVQNQEKDA 1525
Cdd:COG3206    319 EAELEALQAREASLQAQLAQLEARLAELPELEAELRRLEREVEV 362
mukB PRK04863
chromosome partition protein MukB;
2345-2692 8.95e-03

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 41.87  E-value: 8.95e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2345 EQLETDLAASRELTSRLHDEINAKEQKIISLLSGKEEAI--QLAV------EELHQQHSKEIKELENLLSQEEeenvale 2416
Cdd:PRK04863   785 EKRIEQLRAEREELAERYATLSFDVQKLQRLHQAFSRFIgsHLAVafeadpEAELRQLNRRRVELERALADHE------- 857

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2417 eenkralEKTNQLTEALEAIKkesfEQKAQLDSFVKSMSSLQDDR--DRIvsdyRQLEERhLSAILEKDQLIQDAAAENN 2494
Cdd:PRK04863   858 -------SQEQQQRSQLEQAK----EGLSALNRLLPRLNLLADETlaDRV----EEIREQ-LDEAEEAKRFVQQHGNALA 921

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2495 KLKEEMRGLRS---HMDDLNSENAKLDAELVQYR---RDLNEVIAIK------DSQQKQLLDAQL-----QQNKELRNEC 2557
Cdd:PRK04863   922 QLEPIVSVLQSdpeQFEQLKQDYQQAQQTQRDAKqqaFALTEVVQRRahfsyeDAAEMLAKNSDLneklrQRLEQAEQER 1001

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2558 TKLEERLKGLEAE-------KQSLQMSSDALQKEKQGLSKEIKNLQTQLTALQEEgtlgvyhaQLKAKEEElqrLNMALS 2630
Cdd:PRK04863  1002 TRAREQLRQAQAQlaqynqvLASLKSSYDAKRQMLQELKQELQDLGVPADSGAEE--------RARARRDE---LHARLS 1070

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1039751015 2631 SSQKRTADLEEELVCVQKEAtrkvseieDQLKKELKHLHHDAGIMRNETETAEER---VAELARD 2692
Cdd:PRK04863  1071 ANRSRRNQLEKQLTFCEAEM--------DNLTKKLRKLERDYHEMREQVVNAKAGwcaVLRLVKD 1127
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1813-2298 9.18e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 41.82  E-value: 9.18e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1813 VSETFSSHDDIKNYLQQLDQLKGRI----AELEMEKQKDRElsQALENEKNALLTQISAKDSELKLLEEEVTK-RTTLNQ 1887
Cdd:COG4913    257 IRELAERYAAARERLAELEYLRAALrlwfAQRRLELLEAEL--EELRAELARLEAELERLEARLDALREELDElEAQIRG 334

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1888 QIQEELCRVTKLKETAEEEKDDLEERLmNQLAELNGSIGnyYQDVTDAqiknEQLESEMRNLQRCVSELEEEKQQLVKEK 1967
Cdd:COG4913    335 NGGDRLEQLEREIERLERELEERERRR-ARLEALLAALG--LPLPASA----EEFAALRAEAAALLEALEEELEALEEAL 407

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 1968 TKVESEIRkeymekiqgaqkgpankshakELQELLREKQQEVKQLQ--KDCI-RYLERI-----SALEKTVKALEF---- 2035
Cdd:COG4913    408 AEAEAALR---------------------DLRRELRELEAEIASLErrKSNIpARLLALrdalaEALGLDEAELPFvgel 466

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2036 --VHTESQK--------------DLDVTKGNLAQAVEH--RKKAQAELSSFKILLDDTQSEAARVLADNLKLKKELQSNK 2097
Cdd:COG4913    467 ieVRPEEERwrgaiervlggfalTLLVPPEHYAAALRWvnRLHLRGRLVYERVRTGLPDPERPRLDPDSLAGKLDFKPHP 546

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2098 --ESIKSQIKQK-------DEDLLRRLEQA--------EEKHRKEKK-------------NMQEKLDALHREKAHVEETL 2147
Cdd:COG4913    547 frAWLEAELGRRfdyvcvdSPEELRRHPRAitragqvkGNGTRHEKDdrrrirsryvlgfDNRAKLAALEAELAELEEEL 626

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2148 AEIQVSLTRKDQEMKELQGSLDsTLAQLAAFT----------KSMSSLQDDRDRV------IDEAKKWERRFGDAIQTKE 2211
Cdd:COG4913    627 AEAEERLEALEAELDALQERRE-ALQRLAEYSwdeidvasaeREIAELEAELERLdassddLAALEEQLEELEAELEELE 705

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2212 EEVRLKEENCIALKDQLRQMAIHMEELKITVSRLEHDKEIWESKAQTELQHHQKAYDKLQEENKELTSQLEDARQLYHDS 2291
Cdd:COG4913    706 EELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGDAVERELRENLEERIDALRARLNRA 785


                   ....*..
gi 1039751015 2292 KNELTKL 2298
Cdd:COG4913    786 EEELERA 792
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 245-459 9.38e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 41.29  E-value: 9.38e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  245 LLQLVTQSDVETEMQQKLRVMQRKLEEHEEALLGRAQVVDLLQKELTSAEQRNQVLSQQLQLLEAEHNTLK---NTMETE 321
Cdd:COG4942     12 ALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEaelAELEKE 91

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  322 RQESKTLMEKVELEVAER---------------KLSFHNLQEEMHQLQ--GQLERAGQAQADLETQYSALQQRHKTEMEE 384
Cdd:COG4942     92 IAELRAELEAQKEELAELlralyrlgrqpplalLLSPEDFLDAVRRLQylKYLAPARREQAEELRADLAELAALRAELEA 171

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1039751015  385 KTACILSLQKNEQELQSACAALKEENSKLLQEKHDQAAESAQAMRQLEDQLQQKSKEISQFVNKPNLQKNETASQ 459
Cdd:COG4942    172 ERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAA 246
HMMR_N pfam15905
Hyaluronan mediated motility receptor N-terminal; HMMR_N is the N-terminal region of ...
 795-937 9.43e-03

Hyaluronan mediated motility receptor N-terminal; HMMR_N is the N-terminal region of eukaryotic hyaluronan-mediated motility receptor proteins. The protein is functionally associated with BRCA1 and thus predicted to be a common, low-penetrance breast cancer candidate.


Pssm-ID: 464932 [Multi-domain]  Cd Length: 329  Bit Score: 41.34  E-value: 9.43e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015  795 LTEQIHSLSIEAKSKDVKIEALQRELDGVQLQFCEQGTQMKTLQSQLEAKEREVRE---GTERLRDISQEMEGLSQALSQ 871
Cdd:pfam15905  161 LMKLRNKLEAKMKEVMAKQEGMEGKLQVTQKNLEHSKGKVAQLEEKLVSTEKEKIEeksETEKLLEYITELSCVSEQVEK 240

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1039751015  872 KELEIAKMDQLLLEKQKDVETLQQTIQEKDQQVTELSFSMTEKMVQLNEEKFSLGVEIKTLKEQLN 937
Cdd:pfam15905  241 YKLDIAQLEELLKEKNDEIESLKQSLEEKEQELSKQIKDLNEKCKLLESEKEELLREYEEKEQTLN 306
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
2449-2907 9.95e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 41.68  E-value: 9.95e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2449 SFVKSM--SSLQDDRDRIVSDYRQLEERHLSAILEKDQLIQDAAAEN---NKLKEEMRGLRSHMDDLNSENAKLDAELVQ 2523
Cdd:COG4717     41 AFIRAMllERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEeeyAELQEELEELEEELEELEAELEELREELEK 120

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2524 YRRDLNeviaikdsqqkqlLDAQLQQNKELRNECTKLEERLKGLEAEKQSLQmssdALQKEKQGLSKEIKNLQTQLTALQ 2603
Cdd:COG4717    121 LEKLLQ-------------LLPLYQELEALEAELAELPERLEELEERLEELR----ELEEELEELEAELAELQEELEELL 183

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2604 EEGTLgvyhaqlkAKEEELQRLNMALSSSQKRTADLEEELVCVQKEATRKVSEIEdQLKKELKHLHHDAGIMRNETET-A 2682
Cdd:COG4717    184 EQLSL--------ATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELE-QLENELEAAALEERLKEARLLLlI 254

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2683 EERVAELARDLVEMEQKLLTVTKENKDLMAQIQAFGRSMSSLQDSRDHATEELGDLKKKYDASLKELAQLKE--WQDSSR 2760
Cdd:COG4717    255 AAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAalGLPPDL 334

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751015 2761 EGDVLSQAAFPLSTSENVLSRLEKLNQQL------TSKDEQLLHLSSELESSHNQVQSISKAMTSLQNERDRLWSELEKF 2834
Cdd:COG4717    335 SPEELLELLDRIEELQELLREAEELEEELqleeleQEIAALLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEEL 414

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1039751015 2835 RKSEEgkQRAAAPSAASSPAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQMSQEmTELRPLKAQLQESQDQ 2907
Cdd:COG4717    415 LGELE--ELLEALDEEELEEELEELEEELEELEEELEELREELAELEAELEQLEED-GELAELLQELEELKAE 484
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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