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Conserved domains on  [gi|1039751022|ref|XP_017172454|]
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golgin subfamily B member 1 isoform X3 [Mus musculus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1792-2716 6.44e-20

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 98.21  E-value: 6.44e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1792 LDQLKGRIAELE-----MEKQKDR-ELSQALENEKNALLTQISAKDselklLEEEVTKRTTLNQQIQEelcrVTKLKETA 1865
Cdd:TIGR02168  188 LDRLEDILNELErqlksLERQAEKaERYKELKAELRELELALLVLR-----LEELREELEELQEELKE----AEEELEEL 258

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1866 EEEKDDLEErlmnQLAELNGSIGNYYQDVTDAQIKNEQLESEMRNLQRCVSELEEEKQQLVKEKTKVESEIRKeymekiq 1945
Cdd:TIGR02168  259 TAELQELEE----KLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEE------- 327

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1946 gaqkgpaNKSHAKELQELLREKQQEVKQLQKDCIRYLERISALEKTVKALEFVHTESQKDLDVTKGNLAQAVEHRKKAQA 2025
Cdd:TIGR02168  328 -------LESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNN 400

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2026 ELSSFKILLDDTQSEAARVLADNLKLKKELQSNKesiksqikqkdedlLRRLEQAEEKHRKEKKNMQEKLDALHREKAHV 2105
Cdd:TIGR02168  401 EIERLEARLERLEDRRERLQQEIEELLKKLEEAE--------------LKELQAELEELEEELEELQEELERLEEALEEL 466

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2106 EETLAEIQVSLTRKDQEMKELQGSLDStlaqlaafTKSMSSLQDDRDRVIDEAKKWERRFGDAIQTKEE--EVRLKEENC 2183
Cdd:TIGR02168  467 REELEEAEQALDAAERELAQLQARLDS--------LERLQENLEGFSEGVKALLKNQSGLSGILGVLSEliSVDEGYEAA 538

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2184 IALKDQLRQMAIHMEELKITVSRLEHDKEIWESKAqTELQHHQKAYDKLQEENKELTSQLEDARQLYHDSKNELTKLESE 2263
Cdd:TIGR02168  539 IEAALGGRLQAVVVENLNAAKKAIAFLKQNELGRV-TFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKA 617

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2264 LKSLKDQ---TTDLNNSLEKCKehENNLEGIIKQQEADIQNCKFsceqletdlaasreltsrlhdeinakeqkIISLLSG 2340
Cdd:TIGR02168  618 LSYLLGGvlvVDDLDNALELAK--KLRPGYRIVTLDGDLVRPGG-----------------------------VITGGSA 666

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2341 KEEAIQLAVEelhqqhsKEIKELENLLSQEEEENVALEEENKRALEKTNQLTEALEAIKKESFEQKAQLDSFVKSMSSLq 2420
Cdd:TIGR02168  667 KTNSSILERR-------REIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARL- 738

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2421 ddrdrivsdyRQLEERHLSAILEKDQLIQDAAAENNKLKEEMRGLRSHMDDLNSENAKLDAELVQYRRDLNEVIAIKDSQ 2500
Cdd:TIGR02168  739 ----------EAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDEL 808

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2501 QKQLldaqlqqnKELRNECTKLEERLKGLEAEKQSLQMSSDALQKEKQGLSKEIKNLQTQLTALQEEGTlgVYHAQLKAK 2580
Cdd:TIGR02168  809 RAEL--------TLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIE--ELESELEAL 878

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2581 EEELQRLNMALSSSQKRTADLEEELvcvqKEATRKVSEIEDQ---LKKELKHLHHDAGIMRNETETAEERVAELARDLVE 2657
Cdd:TIGR02168  879 LNERASLEEALALLRSELEELSEEL----RELESKRSELRREleeLREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLE 954

                          890       900       910       920       930       940
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2658 M-EQKLLTVTKENKDLMAQIQAFGRSMSSLQDSRDHATEELGDLKKKYDASLKELAQLKE 2716
Cdd:TIGR02168  955 EaEALENKIEDDEEEARRRLKRLENKIKELGPVNLAAIEEYEELKERYDFLTAQKEDLTE 1014
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 274-999 1.17e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 93.97  E-value: 1.17e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  274 NTLKNTMETERQESKTLMEKVELEVAERKLSFHNLQEEMHQLQGQLERAGQAQADLETQYSALQQRHK---TEMEEKTAC 350
Cdd:TIGR02168  245 QEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLAnleRQLEELEAQ 324

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  351 ILSLQKNEQELQSACAALKEENSKLLQEKHDQAA---ESAQAMRQLEDQLQQKSKEISQFVNKPNLQKNETASQTSlpdv 427
Cdd:TIGR02168  325 LEELESKLDELAEELAELEEKLEELKEELESLEAeleELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNN---- 400

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  428 nnegDQAVMEETVASLQKRVVELENEKGALL---------LSSGELEELKAENEKLSSRitLLEAQNRAGEADGTVCEVS 498
Cdd:TIGR02168  401 ----EIERLEARLERLEDRRERLQQEIEELLkkleeaelkELQAELEELEEELEELQEE--LERLEEALEELREELEEAE 474

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  499 TAGTTLLNRSDSSpeENGQAVLENTFsQKHKELSVLLVEMKEAQEEIAFLKSQL-QGKRPEGDYE--------------V 563
Cdd:TIGR02168  475 QALDAAERELAQL--QARLDSLERLQ-ENLEGFSEGVKALLKNQSGLSGILGVLsELISVDEGYEaaieaalggrlqavV 551

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  564 LDRREVQLMESEGPPSVTAGDVLCAPSDESSGPAAEEEQAGMKDRHRaSEAGPLNDagMELSSPKLDGV-DKSLAVSHVC 642
Cdd:TIGR02168  552 VENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIE-GFLGVAKD--LVKFDPKLRKAlSYLLGGVLVV 628

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  643 QCHQGELERLKTqvLELETSLHTAE------------ETYKRNLS--EKVKEISSLTQLSEEVKESAEEARSTLAAVTEE 708
Cdd:TIGR02168  629 DDLDNALELAKK--LRPGYRIVTLDgdlvrpggvitgGSAKTNSSilERRREIEELEEKIEELEEKIAELEKALAELRKE 706

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  709 RDQLlyqvkeLDVLAELRARVQELESSLAEAEKqrglDYESQRAQHNLLTEQIHSLSIEAKSKDVKIEALQRELDGVQLQ 788
Cdd:TIGR02168  707 LEEL------EEELEQLRKELEELSRQISALRK----DLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEE 776

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  789 FCEQGTQMKTLQSQLEAKEREVREGTERLRDISQEMEGLSQALSQKELEIAKMDQLLLEKQKDVETLQQTIQEKDQQVTE 868
Cdd:TIGR02168  777 LAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIES 856

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  869 LSFSMTEKMVQLNEEKfslgveiKTLKEQLNLLSRTEEATKEQVEESGAgSSLKLGHDESGQEGLQQELELLRKESEQRK 948
Cdd:TIGR02168  857 LAAEIEELEELIEELE-------SELEALLNERASLEEALALLRSELEE-LSEELRELESKRSELRRELEELREKLAQLE 928

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1039751022  949 RKLQAALINRKELLQKVS---QLEEELAKVREDSRKEIPFG-ENERRKLEEDREN 999
Cdd:TIGR02168  929 LRLEGLEVRIDNLQERLSeeySLTLEEAEALENKIEDDEEEaRRRLKRLENKIKE 983
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 692-1597 9.87e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 91.27  E-value: 9.87e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  692 KESAEEARSTLAAVTEERDQLLyqvkelDVLAELRARVQELESSLAEAEKQRGLDYESQRAQHNLLTEQIHSLsieaksk 771
Cdd:TIGR02168  171 KERRKETERKLERTRENLDRLE------DILNELERQLKSLERQAEKAERYKELKAELRELELALLVLRLEEL------- 237

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  772 DVKIEALQRELDGVQLQFCEQGTQMKTLQSQLEAKEREVREGTERLRDISQEMEGLSQALSQKELEIAKMDQLLLEKQKD 851
Cdd:TIGR02168  238 REELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQ 317

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  852 VETLQQTIQEKDQQVTElsfsmtekmvqLNEEKFSLGVEIKTLKEQLNLLSRTEEATKEQVEESgagsslklghdESGQE 931
Cdd:TIGR02168  318 LEELEAQLEELESKLDE-----------LAEELAELEEKLEELKEELESLEAELEELEAELEEL-----------ESRLE 375

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  932 GLQQELELLRKESEQRKRKLQAALINRKELLQKVSQLEEELAkvredsrkeipfgenerRKLEEDRENRDDPEEWGTSKW 1011
Cdd:TIGR02168  376 ELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRE-----------------RLQQEIEELLKKLEEAELKEL 438

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1012 REVEASLKQTISEKEVELEGIRRDLKEKTAAEEELQAVVQRMTRDLQSKTKQIDLLqEEVTENQATIQKLVTGTMDAGNG 1091
Cdd:TIGR02168  439 QAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSL-ERLQENLEGFSEGVKALLKNQSG 517

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1092 GSA-APVKETAASSPPGaggeehWKPELE----GRILDLEKDKTQLQKKLQEALiarkailkKAQEKEKQLKEELREQKD 1166
Cdd:TIGR02168  518 LSGiLGVLSELISVDEG------YEAAIEaalgGRLQAVVVENLNAAKKAIAFL--------KQNELGRVTFLPLDSIKG 583

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1167 AyhHLQGQFHEQNKEKENIADQLRQLqcqarESIDRQLPGTGQqepgppaPSLEGISLEDTepaSESDLHAAQPSPPGET 1246
Cdd:TIGR02168  584 T--EIQGNDREILKNIEGFLGVAKDL-----VKFDPKLRKALS-------YLLGGVLVVDD---LDNALELAKKLRPGYR 646

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1247 AALQATVSVAQIQAQLKEMEVEKEELELKVssiaSELAKKSEEVLLLQDQINEQGLEIQNLKAASVEAQAHTELLKQELE 1326
Cdd:TIGR02168  647 IVTLDGDLVRPGGVITGGSAKTNSSILERR----REIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELE 722

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1327 SSQLKVAGL-EHLKTLQPELDALHKHMGQKEEEVNYLYGQLSEKEQTLTTVQTEMVEQERLIKalhtQLEMQAKEHEERL 1405
Cdd:TIGR02168  723 ELSRQISALrKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIE----ELEAQIEQLKEEL 798

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1406 KQAQVEICELKKKPTELEEE----TNAKQQLQRKLQAALISRKEALKENKSLQEQLSSARDAVERLTKSLADVESQVSVQ 1481
Cdd:TIGR02168  799 KALREALDELRAELTLLNEEaanlRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEAL 878

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1482 NQEKDAVLGKLTILQEERDKLIAEMDRFLLENQSLSGSCESLKLALGGLTEDKEKLMEELESVRSSKMAestewqekhkE 1561
Cdd:TIGR02168  879 LNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSE----------E 948

                          890       900       910
                   ....*....|....*....|....*....|....*.
gi 1039751022 1562 LQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQEL 1597
Cdd:TIGR02168  949 YSLTLEEAEALENKIEDDEEEARRRLKRLENKIKEL 984
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2381-3122 6.99e-10

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 65.46  E-value: 6.99e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2381 NKRALEKTNQLTEALEAIKKEsfEQKAQLDSFVKSMSSLQDDRDR---IVSDYRQLEERHLSAILEKDQLIQDAAAENNK 2457
Cdd:TIGR02168  201 QLKSLERQAEKAERYKELKAE--LRELELALLVLRLEELREELEElqeELKEAEEELEELTAELQELEEKLEELRLEVSE 278

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2458 LKEEMRGLRSHMDDLNSENAKLDAELVQYRRDLNEViaikdSQQKQLLDAQLQQNKELRNEctkLEERLKGLEAEKQSLQ 2537
Cdd:TIGR02168  279 LEEEIEELQKELYALANEISRLEQQKQILRERLANL-----ERQLEELEAQLEELESKLDE---LAEELAELEEKLEELK 350

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2538 MSSDALQKEKQGLSKEIKNLQTQLTALQEEgtlgvyHAQLKAKEEELQRlnmALSSSQKRTADLEEELVCVQKEATRKVS 2617
Cdd:TIGR02168  351 EELESLEAELEELEAELEELESRLEELEEQ------LETLRSKVAQLEL---QIASLNNEIERLEARLERLEDRRERLQQ 421

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2618 EIEDQLKKELKHLHHDAGIMRNETETAEErvaELARDLVEMEQKLLTVTKENKDLMAQIQAFGRSMSSLQdSRDHATEEL 2697
Cdd:TIGR02168  422 EIEELLKKLEEAELKELQAELEELEEELE---ELQEELERLEEALEELREELEEAEQALDAAERELAQLQ-ARLDSLERL 497

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2698 GDLKKKYDASLKELAQLKEWqdssregdvLSQAAFPLSTSENVLSRLEKLNQQLTSKDEQLLhLSSELESSHNQVQSISK 2777
Cdd:TIGR02168  498 QENLEGFSEGVKALLKNQSG---------LSGILGVLSELISVDEGYEAAIEAALGGRLQAV-VVENLNAAKKAIAFLKQ 567

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2778 AmtslqNERDRLWSELEKFRKSE-EGKQRAAAPSAASSPAEVQSLKKAMSSLQNDRDRLL------KELKNLQQQYLQMS 2850
Cdd:TIGR02168  568 N-----ELGRVTFLPLDSIKGTEiQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLggvlvvDDLDNALELAKKLR 642

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2851 QEMT-------------------------------ELRPLKAQLQESQDQTKALQVMEEELRQENLSWQHELRQLRMEKN 2899
Cdd:TIGR02168  643 PGYRivtldgdlvrpggvitggsaktnssilerrrEIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELE 722

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2900 SWELHERRMKEQfLMAISDKDQQLGHLQSLLRELRSSSQAQILSTQYQR-QASPETSASLDGSQKLVYETELLRTQLNDS 2978
Cdd:TIGR02168  723 ELSRQISALRKD-LARLEAEVEQLEERIAQLSKELTELEAEIEELEERLeEAEEELAEAEAEIEELEAQIEQLKEELKAL 801

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2979 LKEIHQKELRIQQLNSKFSQLLEEKNVLSTQLSDASQSLRENQHHYSNLFNHCAILEKEVQKLQAGP--LNTDVapgapq 3056
Cdd:TIGR02168  802 REALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIeeLESEL------ 875

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1039751022 3057 EKNGMHRKSEPETTGEEQPSFSEVQQQLCNTKQDLRELKKLLEEERDQRLTAENALSLAKEQIRRL 3122
Cdd:TIGR02168  876 EALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNL 941
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 9-272 1.38e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 54.56  E-value: 1.38e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022    9 ESTQEDALHRLAEAEKLVVELKDIISQKDVQLQQKDEALQEEKKAAENKIKKIKlHAKAKIMSLNKHMEEIKTQGgaalp 88
Cdd:COG1196    252 EAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIA-RLEERRRELEERLEELEEEL----- 325

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022   89 pEAQAEELSKHNKSSTEEEMEIEKIKHELQEKEKLISSLQAQLdqSEQASQLDKSSAEMEDFVLMKQQLQEKEELISTLQ 168
Cdd:COG1196    326 -AELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEAL--LEAEAELAEAEEELEELAEELLEALRAAAELAAQL 402

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  169 TQLSQTQAEQAAQLSSMQQVVREKDARFETQVRLHEDELLQLVTQSDVETEMQQKLRVMQRKLEEHEEALLGRAQVVDLL 248
Cdd:COG1196    403 EELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAEL 482

                          250       260
                   ....*....|....*....|....
gi 1039751022  249 QKELTSAEQRNQVLSQQLQLLEAE 272
Cdd:COG1196    483 LEELAEAAARLLLLLEAEADYEGF 506
EnvC super family cl34844
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1672-1883 5.63e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG4942:

Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.14  E-value: 5.63e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1672 SSLKEELEKITLEHKTLSKEFEALMAEKDALSEETRNLKLQVEA--QVLKQASLEATEKSDEPKDVIEEVTQAVVGKSQE 1749
Cdd:COG4942     23 AEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAAlaRRIRALEQELAALEAELAELEKEIAELRAELEAQ 102

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1750 RDALSDSAKledsEAILMGDGAKPGV---SETFSSHDDIKNYLQQL-DQLKGRIAELEMEKQKDRELSQALENEKNALLT 1825
Cdd:COG4942    103 KEELAELLR----ALYRLGRQPPLALllsPEDFLDAVRRLQYLKYLaPARREQAEELRADLAELAALRAELEAERAELEA 178

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1039751022 1826 QISAKDSELKLLEEEVTKRTTLNQQIQEELcrvtKLKETAEEEKDDLEERLMNQLAEL 1883
Cdd:COG4942    179 LLAELEEERAALEALKAERQKLLARLEKEL----AELAAELAELQQEAEELEALIARL 232
 
Name Accession Description Interval E-value
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1792-2716 6.44e-20

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 98.21  E-value: 6.44e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1792 LDQLKGRIAELE-----MEKQKDR-ELSQALENEKNALLTQISAKDselklLEEEVTKRTTLNQQIQEelcrVTKLKETA 1865
Cdd:TIGR02168  188 LDRLEDILNELErqlksLERQAEKaERYKELKAELRELELALLVLR-----LEELREELEELQEELKE----AEEELEEL 258

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1866 EEEKDDLEErlmnQLAELNGSIGNYYQDVTDAQIKNEQLESEMRNLQRCVSELEEEKQQLVKEKTKVESEIRKeymekiq 1945
Cdd:TIGR02168  259 TAELQELEE----KLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEE------- 327

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1946 gaqkgpaNKSHAKELQELLREKQQEVKQLQKDCIRYLERISALEKTVKALEFVHTESQKDLDVTKGNLAQAVEHRKKAQA 2025
Cdd:TIGR02168  328 -------LESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNN 400

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2026 ELSSFKILLDDTQSEAARVLADNLKLKKELQSNKesiksqikqkdedlLRRLEQAEEKHRKEKKNMQEKLDALHREKAHV 2105
Cdd:TIGR02168  401 EIERLEARLERLEDRRERLQQEIEELLKKLEEAE--------------LKELQAELEELEEELEELQEELERLEEALEEL 466

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2106 EETLAEIQVSLTRKDQEMKELQGSLDStlaqlaafTKSMSSLQDDRDRVIDEAKKWERRFGDAIQTKEE--EVRLKEENC 2183
Cdd:TIGR02168  467 REELEEAEQALDAAERELAQLQARLDS--------LERLQENLEGFSEGVKALLKNQSGLSGILGVLSEliSVDEGYEAA 538

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2184 IALKDQLRQMAIHMEELKITVSRLEHDKEIWESKAqTELQHHQKAYDKLQEENKELTSQLEDARQLYHDSKNELTKLESE 2263
Cdd:TIGR02168  539 IEAALGGRLQAVVVENLNAAKKAIAFLKQNELGRV-TFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKA 617

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2264 LKSLKDQ---TTDLNNSLEKCKehENNLEGIIKQQEADIQNCKFsceqletdlaasreltsrlhdeinakeqkIISLLSG 2340
Cdd:TIGR02168  618 LSYLLGGvlvVDDLDNALELAK--KLRPGYRIVTLDGDLVRPGG-----------------------------VITGGSA 666

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2341 KEEAIQLAVEelhqqhsKEIKELENLLSQEEEENVALEEENKRALEKTNQLTEALEAIKKESFEQKAQLDSFVKSMSSLq 2420
Cdd:TIGR02168  667 KTNSSILERR-------REIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARL- 738

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2421 ddrdrivsdyRQLEERHLSAILEKDQLIQDAAAENNKLKEEMRGLRSHMDDLNSENAKLDAELVQYRRDLNEVIAIKDSQ 2500
Cdd:TIGR02168  739 ----------EAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDEL 808

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2501 QKQLldaqlqqnKELRNECTKLEERLKGLEAEKQSLQMSSDALQKEKQGLSKEIKNLQTQLTALQEEGTlgVYHAQLKAK 2580
Cdd:TIGR02168  809 RAEL--------TLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIE--ELESELEAL 878

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2581 EEELQRLNMALSSSQKRTADLEEELvcvqKEATRKVSEIEDQ---LKKELKHLHHDAGIMRNETETAEERVAELARDLVE 2657
Cdd:TIGR02168  879 LNERASLEEALALLRSELEELSEEL----RELESKRSELRREleeLREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLE 954

                          890       900       910       920       930       940
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2658 M-EQKLLTVTKENKDLMAQIQAFGRSMSSLQDSRDHATEELGDLKKKYDASLKELAQLKE 2716
Cdd:TIGR02168  955 EaEALENKIEDDEEEARRRLKRLENKIKELGPVNLAAIEEYEELKERYDFLTAQKEDLTE 1014
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 274-999 1.17e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 93.97  E-value: 1.17e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  274 NTLKNTMETERQESKTLMEKVELEVAERKLSFHNLQEEMHQLQGQLERAGQAQADLETQYSALQQRHK---TEMEEKTAC 350
Cdd:TIGR02168  245 QEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLAnleRQLEELEAQ 324

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  351 ILSLQKNEQELQSACAALKEENSKLLQEKHDQAA---ESAQAMRQLEDQLQQKSKEISQFVNKPNLQKNETASQTSlpdv 427
Cdd:TIGR02168  325 LEELESKLDELAEELAELEEKLEELKEELESLEAeleELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNN---- 400

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  428 nnegDQAVMEETVASLQKRVVELENEKGALL---------LSSGELEELKAENEKLSSRitLLEAQNRAGEADGTVCEVS 498
Cdd:TIGR02168  401 ----EIERLEARLERLEDRRERLQQEIEELLkkleeaelkELQAELEELEEELEELQEE--LERLEEALEELREELEEAE 474

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  499 TAGTTLLNRSDSSpeENGQAVLENTFsQKHKELSVLLVEMKEAQEEIAFLKSQL-QGKRPEGDYE--------------V 563
Cdd:TIGR02168  475 QALDAAERELAQL--QARLDSLERLQ-ENLEGFSEGVKALLKNQSGLSGILGVLsELISVDEGYEaaieaalggrlqavV 551

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  564 LDRREVQLMESEGPPSVTAGDVLCAPSDESSGPAAEEEQAGMKDRHRaSEAGPLNDagMELSSPKLDGV-DKSLAVSHVC 642
Cdd:TIGR02168  552 VENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIE-GFLGVAKD--LVKFDPKLRKAlSYLLGGVLVV 628

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  643 QCHQGELERLKTqvLELETSLHTAE------------ETYKRNLS--EKVKEISSLTQLSEEVKESAEEARSTLAAVTEE 708
Cdd:TIGR02168  629 DDLDNALELAKK--LRPGYRIVTLDgdlvrpggvitgGSAKTNSSilERRREIEELEEKIEELEEKIAELEKALAELRKE 706

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  709 RDQLlyqvkeLDVLAELRARVQELESSLAEAEKqrglDYESQRAQHNLLTEQIHSLSIEAKSKDVKIEALQRELDGVQLQ 788
Cdd:TIGR02168  707 LEEL------EEELEQLRKELEELSRQISALRK----DLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEE 776

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  789 FCEQGTQMKTLQSQLEAKEREVREGTERLRDISQEMEGLSQALSQKELEIAKMDQLLLEKQKDVETLQQTIQEKDQQVTE 868
Cdd:TIGR02168  777 LAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIES 856

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  869 LSFSMTEKMVQLNEEKfslgveiKTLKEQLNLLSRTEEATKEQVEESGAgSSLKLGHDESGQEGLQQELELLRKESEQRK 948
Cdd:TIGR02168  857 LAAEIEELEELIEELE-------SELEALLNERASLEEALALLRSELEE-LSEELRELESKRSELRRELEELREKLAQLE 928

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1039751022  949 RKLQAALINRKELLQKVS---QLEEELAKVREDSRKEIPFG-ENERRKLEEDREN 999
Cdd:TIGR02168  929 LRLEGLEVRIDNLQERLSeeySLTLEEAEALENKIEDDEEEaRRRLKRLENKIKE 983
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 692-1597 9.87e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 91.27  E-value: 9.87e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  692 KESAEEARSTLAAVTEERDQLLyqvkelDVLAELRARVQELESSLAEAEKQRGLDYESQRAQHNLLTEQIHSLsieaksk 771
Cdd:TIGR02168  171 KERRKETERKLERTRENLDRLE------DILNELERQLKSLERQAEKAERYKELKAELRELELALLVLRLEEL------- 237

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  772 DVKIEALQRELDGVQLQFCEQGTQMKTLQSQLEAKEREVREGTERLRDISQEMEGLSQALSQKELEIAKMDQLLLEKQKD 851
Cdd:TIGR02168  238 REELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQ 317

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  852 VETLQQTIQEKDQQVTElsfsmtekmvqLNEEKFSLGVEIKTLKEQLNLLSRTEEATKEQVEESgagsslklghdESGQE 931
Cdd:TIGR02168  318 LEELEAQLEELESKLDE-----------LAEELAELEEKLEELKEELESLEAELEELEAELEEL-----------ESRLE 375

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  932 GLQQELELLRKESEQRKRKLQAALINRKELLQKVSQLEEELAkvredsrkeipfgenerRKLEEDRENRDDPEEWGTSKW 1011
Cdd:TIGR02168  376 ELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRE-----------------RLQQEIEELLKKLEEAELKEL 438

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1012 REVEASLKQTISEKEVELEGIRRDLKEKTAAEEELQAVVQRMTRDLQSKTKQIDLLqEEVTENQATIQKLVTGTMDAGNG 1091
Cdd:TIGR02168  439 QAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSL-ERLQENLEGFSEGVKALLKNQSG 517

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1092 GSA-APVKETAASSPPGaggeehWKPELE----GRILDLEKDKTQLQKKLQEALiarkailkKAQEKEKQLKEELREQKD 1166
Cdd:TIGR02168  518 LSGiLGVLSELISVDEG------YEAAIEaalgGRLQAVVVENLNAAKKAIAFL--------KQNELGRVTFLPLDSIKG 583

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1167 AyhHLQGQFHEQNKEKENIADQLRQLqcqarESIDRQLPGTGQqepgppaPSLEGISLEDTepaSESDLHAAQPSPPGET 1246
Cdd:TIGR02168  584 T--EIQGNDREILKNIEGFLGVAKDL-----VKFDPKLRKALS-------YLLGGVLVVDD---LDNALELAKKLRPGYR 646

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1247 AALQATVSVAQIQAQLKEMEVEKEELELKVssiaSELAKKSEEVLLLQDQINEQGLEIQNLKAASVEAQAHTELLKQELE 1326
Cdd:TIGR02168  647 IVTLDGDLVRPGGVITGGSAKTNSSILERR----REIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELE 722

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1327 SSQLKVAGL-EHLKTLQPELDALHKHMGQKEEEVNYLYGQLSEKEQTLTTVQTEMVEQERLIKalhtQLEMQAKEHEERL 1405
Cdd:TIGR02168  723 ELSRQISALrKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIE----ELEAQIEQLKEEL 798

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1406 KQAQVEICELKKKPTELEEE----TNAKQQLQRKLQAALISRKEALKENKSLQEQLSSARDAVERLTKSLADVESQVSVQ 1481
Cdd:TIGR02168  799 KALREALDELRAELTLLNEEaanlRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEAL 878

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1482 NQEKDAVLGKLTILQEERDKLIAEMDRFLLENQSLSGSCESLKLALGGLTEDKEKLMEELESVRSSKMAestewqekhkE 1561
Cdd:TIGR02168  879 LNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSE----------E 948

                          890       900       910
                   ....*....|....*....|....*....|....*.
gi 1039751022 1562 LQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQEL 1597
Cdd:TIGR02168  949 YSLTLEEAEALENKIEDDEEEARRRLKRLENKIKEL 984
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 720-1362 7.88e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 78.05  E-value: 7.88e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  720 DVLAELRARVQELESSLAEAEKQRGLDYESQRAQHNLLTEQIHSLSIEAKSKDVKIEALQRELdgvqlqfceqgtqmKTL 799
Cdd:COG1196    193 DILGELERQLEPLERQAEKAERYRELKEELKELEAELLLLKLRELEAELEELEAELEELEAEL--------------EEL 258

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  800 QSQLEAKEREVREGTERLRDISQEMEGLSQALSQKELEIAKMDQLLLEKQKDVETLQQTIQEKDQQVTELsfsmTEKMVQ 879
Cdd:COG1196    259 EAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAEL----EEELEE 334

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  880 LNEEKFSLGVEIKTLKEQLNLLSRTEEATKEQVEEsgagsslklghDESGQEGLQQELELLRKESEQRKRKLQAALINRK 959
Cdd:COG1196    335 LEEELEELEEELEEAEEELEEAEAELAEAEEALLE-----------AEAELAEAEEELEELAEELLEALRAAAELAAQLE 403

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  960 ELLQKVSQLEEELAKVREDSRKEipfgENERRKLEEDRENRddpeewgtskwREVEASLKQTISEKEVELEGIRRDLKEK 1039
Cdd:COG1196    404 ELEEAEEALLERLERLEEELEEL----EEALAELEEEEEEE-----------EEALEEAAEEEAELEEEEEALLELLAEL 468

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1040 TAAEEELQAVVQRMTRDLQSKTKQIDLLQEEVTEnqatiqklvtgtMDAGNGGSAAPVKETAASSPPGAGGEEHWKPELE 1119
Cdd:COG1196    469 LEEAALLEAALAELLEELAEAAARLLLLLEAEAD------------YEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAY 536

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1120 GRILDLEKDKTQLQKKLQEALIARKAILKKAQEKEKQLKEELREQKDAYHHLQGQFHEQNKEKENIADQLRQLQCQARES 1199
Cdd:COG1196    537 EAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYY 616

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1200 IDRQLPGTGQQEPGPPAPSLEGISLEDTEPASESDLHAAQPSPPGETAALQATVSVAQIQAQLKEMEVEKEELELKVSSI 1279
Cdd:COG1196    617 VLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELE 696

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1280 ASELAKKSEEVLLLQDQINEQGLEIQNLKAASVEAQAHTELLKQELESSQLKVAGLEHLKTLQPELDALHKHMGQKEEEV 1359
Cdd:COG1196    697 EALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREI 776


                   ...
gi 1039751022 1360 NYL 1362
Cdd:COG1196    777 EAL 779
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1365-1938 1.13e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 77.67  E-value: 1.13e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1365 QLSEKEQTLTTVQTEMVEQERLIKALHTQLEMQAKEHEERLKQAQVEICELKKKPTELEE----ETNAKQQLQRKLQAAL 1440
Cdd:COG1196    243 ELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQdiarLEERRRELEERLEELE 322

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1441 ISRKEALKENKSLQEQLSSARDAVERLTKSLADVESQVSVQNQEKDAVLGKLTILQEERDKLIAEMDRFLLENQSLSGSC 1520
Cdd:COG1196    323 EELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQL 402

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1521 ESLKLALGGLTEDKEKLMEELESVRSSKMAESTEWQEKHKELQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQELYAK 1600
Cdd:COG1196    403 EELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAEL 482

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1601 LRSTESDKREREKQLQDAEQEMEEMKEKMRKFAKSKQQKILEL--EEENDRLRAEAQPVGGTGESMEALLSSNSSLKEEL 1678
Cdd:COG1196    483 LEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAvaVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAA 562

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1679 EKITLEHKTLSKEFEAL-MAEKDALSEETRNLKLQVEAQVLKQASLEATEKSDEPKDVIEEVTQAVVGKSQERDALSDSA 1757
Cdd:COG1196    563 IEYLKAAKAGRATFLPLdKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTL 642

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1758 KLEDSEAILMGDGAKPGVSETfsshddiknylqqLDQLKGRIAELEMEKQKDRELSQALENEKNALLTQISAKDSELKLL 1837
Cdd:COG1196    643 AGRLREVTLEGEGGSAGGSLT-------------GGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEEREL 709

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1838 EEEVTKRTTLNQQIQEELCRVTKLKETAEEEKDDLEERLMNQLAELNGSIgnyyQDVTDAQIKNEQLESEMRNLQRcV-- 1915
Cdd:COG1196    710 AEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEP----PDLEELERELERLEREIEALGP-Vnl 784

                          570       580
                   ....*....|....*....|....*....
gi 1039751022 1916 ------SELEEEKQQLVKEKTKVESEIRK 1938
Cdd:COG1196    785 laieeyEELEERYDFLSEQREDLEEARET 813
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 646-1220 1.55e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 73.82  E-value: 1.55e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  646 QGELERLKTQVLELETSLHTAEETYKRNLSEKVKEISSLTQLSEEVKESAEEARSTLAAVTEERDQLLYQVKELDVLAEL 725
Cdd:COG1196    238 EAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEER 317

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  726 RARVQELESSLAEAEKQRGLDYESQRAQHNLLTEQIHSLSIEAKSKDVKIEALQRELDGVQLQFCEQGTQMKTLQSQLEA 805
Cdd:COG1196    318 LEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAE 397

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  806 KEREVREGTERLRDISQEMEGLSQALSQKELEIAKMDQLLLEKQKDVETLQQTIQEKDQQVTELsfsmTEKMVQLNEEKF 885
Cdd:COG1196    398 LAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEAL----LELLAELLEEAA 473

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  886 SLGVEIKTLKEQLNLLSRTEEATKE-QVEESGAGSSLKLGHDESGQEGLQQELELLRKESEQRKRKLQAALInrkELLQK 964
Cdd:COG1196    474 LLEAALAELLEELAEAAARLLLLLEaEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALA---AALQN 550

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  965 VSQLEEELAKVREDSRKEIPFGENERRKLEEDRENRDDPeewgtskwrevEASLKQTISEKEVELEGIRRDLKEKTAAEE 1044
Cdd:COG1196    551 IVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALA-----------AALARGAIGAAVDLVASDLREADARYYVLG 619

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1045 ELQAVVQRMTRDLQSKTKQIDLLQEEVTEnqatiqklVTGTMDAGNGGSAapvketaassppgaggeehwkpelEGRILD 1124
Cdd:COG1196    620 DTLLGRTLVAARLEAALRRAVTLAGRLRE--------VTLEGEGGSAGGS------------------------LTGGSR 667

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1125 LEKDKTQLQKKLQEALIARKAILKKAQEKEKQLKEELREQKDAYHHLQGQFHEQNKEKENIADQLRQLQCQARESIDRQL 1204
Cdd:COG1196    668 RELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEEL 747

                          570
                   ....*....|....*.
gi 1039751022 1205 PGTGQQEPGPPAPSLE 1220
Cdd:COG1196    748 LEEEALEELPEPPDLE 763
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2381-3122 6.99e-10

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 65.46  E-value: 6.99e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2381 NKRALEKTNQLTEALEAIKKEsfEQKAQLDSFVKSMSSLQDDRDR---IVSDYRQLEERHLSAILEKDQLIQDAAAENNK 2457
Cdd:TIGR02168  201 QLKSLERQAEKAERYKELKAE--LRELELALLVLRLEELREELEElqeELKEAEEELEELTAELQELEEKLEELRLEVSE 278

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2458 LKEEMRGLRSHMDDLNSENAKLDAELVQYRRDLNEViaikdSQQKQLLDAQLQQNKELRNEctkLEERLKGLEAEKQSLQ 2537
Cdd:TIGR02168  279 LEEEIEELQKELYALANEISRLEQQKQILRERLANL-----ERQLEELEAQLEELESKLDE---LAEELAELEEKLEELK 350

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2538 MSSDALQKEKQGLSKEIKNLQTQLTALQEEgtlgvyHAQLKAKEEELQRlnmALSSSQKRTADLEEELVCVQKEATRKVS 2617
Cdd:TIGR02168  351 EELESLEAELEELEAELEELESRLEELEEQ------LETLRSKVAQLEL---QIASLNNEIERLEARLERLEDRRERLQQ 421

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2618 EIEDQLKKELKHLHHDAGIMRNETETAEErvaELARDLVEMEQKLLTVTKENKDLMAQIQAFGRSMSSLQdSRDHATEEL 2697
Cdd:TIGR02168  422 EIEELLKKLEEAELKELQAELEELEEELE---ELQEELERLEEALEELREELEEAEQALDAAERELAQLQ-ARLDSLERL 497

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2698 GDLKKKYDASLKELAQLKEWqdssregdvLSQAAFPLSTSENVLSRLEKLNQQLTSKDEQLLhLSSELESSHNQVQSISK 2777
Cdd:TIGR02168  498 QENLEGFSEGVKALLKNQSG---------LSGILGVLSELISVDEGYEAAIEAALGGRLQAV-VVENLNAAKKAIAFLKQ 567

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2778 AmtslqNERDRLWSELEKFRKSE-EGKQRAAAPSAASSPAEVQSLKKAMSSLQNDRDRLL------KELKNLQQQYLQMS 2850
Cdd:TIGR02168  568 N-----ELGRVTFLPLDSIKGTEiQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLggvlvvDDLDNALELAKKLR 642

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2851 QEMT-------------------------------ELRPLKAQLQESQDQTKALQVMEEELRQENLSWQHELRQLRMEKN 2899
Cdd:TIGR02168  643 PGYRivtldgdlvrpggvitggsaktnssilerrrEIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELE 722

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2900 SWELHERRMKEQfLMAISDKDQQLGHLQSLLRELRSSSQAQILSTQYQR-QASPETSASLDGSQKLVYETELLRTQLNDS 2978
Cdd:TIGR02168  723 ELSRQISALRKD-LARLEAEVEQLEERIAQLSKELTELEAEIEELEERLeEAEEELAEAEAEIEELEAQIEQLKEELKAL 801

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2979 LKEIHQKELRIQQLNSKFSQLLEEKNVLSTQLSDASQSLRENQHHYSNLFNHCAILEKEVQKLQAGP--LNTDVapgapq 3056
Cdd:TIGR02168  802 REALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIeeLESEL------ 875

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1039751022 3057 EKNGMHRKSEPETTGEEQPSFSEVQQQLCNTKQDLRELKKLLEEERDQRLTAENALSLAKEQIRRL 3122
Cdd:TIGR02168  876 EALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNL 941
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1873-2443 3.42e-09

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 62.77  E-value: 3.42e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1873 EERLMNQLAELNGSIGNYYQDVTDAQIKNEQLESEMRNLQRCVSELEEEKQ---QLVKEKTKVESEIRKEyMEKIQGAQK 1949
Cdd:PRK03918   188 TENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEeieELEKELESLEGSKRKL-EEKIRELEE 266

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1950 GPANKshaKELQELLREKQQEVKQLQKDCIRYLERISALEKTVKALefvhtesqKDLDVTKGNLAQAVEHRKKAQAELSS 2029
Cdd:PRK03918   267 RIEEL---KKEIEELEEKVKELKELKEKAEEYIKLSEFYEEYLDEL--------REIEKRLSRLEEEINGIEERIKELEE 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2030 FKILLDDTQseaarvladnlKLKKELQSNKESIKSQIKQKDEdlLRRLEQAEEKHRKEKKN-----MQEKLDALHREKAH 2104
Cdd:PRK03918   336 KEERLEELK-----------KKLKELEKRLEELEERHELYEE--AKAKKEELERLKKRLTGltpekLEKELEELEKAKEE 402

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2105 VEETLAEIQVSLTRKDQEMKELQGSL-------------------DSTLAQLAAFTKSMSSLQDDRDRVIDEAKKWERRF 2165
Cdd:PRK03918   403 IEEEISKITARIGELKKEIKELKKAIeelkkakgkcpvcgrelteEHRKELLEEYTAELKRIEKELKEIEEKERKLRKEL 482

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2166 gdaiqTKEEEVRLKEENCIALKDQLRQMAIHMEELKitvsrlEHDKEIWESKAqTELQHHQKAYDKLQEENKELTSQLED 2245
Cdd:PRK03918   483 -----RELEKVLKKESELIKLKELAEQLKELEEKLK------KYNLEELEKKA-EEYEKLKEKLIKLKGEIKSLKKELEK 550

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2246 ARQLyhdsKNELTKLESELKSLKDQTTDLNNSLEKCK-EHENNLEGIIKQQEA------DIQNCKFSCEQLETDLAASRE 2318
Cdd:PRK03918   551 LEEL----KKKLAELEKKLDELEEELAELLKELEELGfESVEELEERLKELEPfyneylELKDAEKELEREEKELKKLEE 626

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2319 LTSRLHDEINAKEQKIISLLSGKEEAIQLAVEELHQQHSKEIKELENLLSQEEEENVALEEENKRALEKTNQLTEALEAI 2398
Cdd:PRK03918   627 ELDKAFEELAETEKRLEELRKELEELEKKYSEEEYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEER 706

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*
gi 1039751022 2399 KKesfeQKAQLDSFVKSMSSLQDDRDRIVSDYRQLEERHLSAILE 2443
Cdd:PRK03918   707 EK----AKKELEKLEKALERVEELREKVKKYKALLKERALSKVGE 747
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 696-1182 7.76e-09

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 61.78  E-value: 7.76e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  696 EEARSTLAAVTEERDQLLYQVKELDVLAELRARVQELESSLAEAEKQRGLDYESQ-RAQHNLLTEQIHSLSIEAKSKDVK 774
Cdd:pfam12128  237 MKIRPEFTKLQQEFNTLESAELRLSHLHFGYKSDETLIASRQEERQETSAELNQLlRTLDDQWKEKRDELNGELSAADAA 316

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  775 IEALQRELDGVQ---LQFCEQG--------TQMKTLQSQLEAKEREVREGTERLRDISQEMEGLSQALSQK-ELEIAKMD 842
Cdd:pfam12128  317 VAKDRSELEALEdqhGAFLDADietaaadqEQLPSWQSELENLEERLKALTGKHQDVTAKYNRRRSKIKEQnNRDIAGIK 396

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  843 QLLlEKQKDVETLQQTIQEKD--QQVTELSFSMTEKMVQLNEEKFSLGVEIKTLKEQLNLLSRTEE--ATKEQVEESGAG 918
Cdd:pfam12128  397 DKL-AKIREARDRQLAVAEDDlqALESELREQLEAGKLEFNEEEYRLKSRLGELKLRLNQATATPEllLQLENFDERIER 475

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  919 SSLKLGHDESGQEGLQQELELLRKESEQRKRKLQAALINRKELLQKVSQLEEEL----AKVREDSRKEIP-FGENERRKL 993
Cdd:pfam12128  476 AREEQEAANAEVERLQSELRQARKRRDQASEALRQASRRLEERQSALDELELQLfpqaGTLLHFLRKEAPdWEQSIGKVI 555

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  994 EEDRENRDD--PEEWgtskwrevEASLKQTISEKEVELEGIRRDLKEKTAAEEELQAVVQRMTRDLQSKTKQIDLLQEEV 1071
Cdd:pfam12128  556 SPELLHRTDldPEVW--------DGSVGGELNLYGVKLDLKRIDVPEWAASEEELRERLDKAEEALQSAREKQAAAEEQL 627

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1072 TENQATIQKLVTGTMDAGNGGSAApvketaassppgaggeehwkpelEGRILDLEKDKTQLQKKLQEALIARKA-ILKKA 1150
Cdd:pfam12128  628 VQANGELEKASREETFARTALKNA-----------------------RLDLRRLFDEKQSEKDKKNKALAERKDsANERL 684

                          490       500       510
                   ....*....|....*....|....*....|..
gi 1039751022 1151 QEKEKQLKEELREQKDAYHHLQGQFHEQNKEK 1182
Cdd:pfam12128  685 NSLEAQLKQLDKKHQAWLEEQKEQKREARTEK 716
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1785-2556 2.30e-07

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 56.90  E-value: 2.30e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1785 IKNYLQQLDQLKGRIAELEMEKQKDRELSQALENEKNALLTQISAKDSELKLLEEEVTKRttlnQQIQEELCRVTKLKET 1864
Cdd:pfam02463  281 KKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEEL----EKELKELEIKREAEEE 356

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1865 AEEEKDDLEERLMNQLAELNGSIGNYYQDVTDAQIKNEQLESEMRNLQRCVS---ELEEEKQQLVKEKTKVESEIRKEYM 1941
Cdd:pfam02463  357 EEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQlllELARQLEDLLKEEKKEELEILEEEE 436

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1942 EKIQGAQKGPANKSHAKELQELLREKQQEVKQLQKDcirylerisalektvkalefvhtesqkdldvtKGNLAQAVEHRK 2021
Cdd:pfam02463  437 ESIELKQGKLTEEKEELEKQELKLLKDELELKKSED--------------------------------LLKETQLVKLQE 484

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2022 KAQAELSSFKILLDDTQSEAARVLADNLKLKKELQSNKESIKSQIKQKDEDLLRRLEQAEEKHRKEKKNMQEKLDALHRE 2101
Cdd:pfam02463  485 QLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQ 564

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2102 KAHVEETLAEIQVSLTRKDQEMKELQGSLDSTLAQLAAfTKSMSSLQDDRDRVIDEAKKWERRFGDAIQTKEEEVRLKEE 2181
Cdd:pfam02463  565 KLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPI-LNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKA 643

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2182 NCIALKDQLRQMAIHMEELKITVSRLEHDKEIWESKAQTELQHHQKAYDKLQEENKELTSQLEDARQLYHDSKNELTKLE 2261
Cdd:pfam02463  644 KESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELL 723

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2262 SELKSLKDQTTDLNNSLEKCKEHENNLEGIIKQQEADIQNCKFSCEQLETDLAASReltsRLHDEINAKEQKIISLLSGK 2341
Cdd:pfam02463  724 ADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEE----REKTEKLKVEEEKEEKLKAQ 799

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2342 EEAIQLAVEELHQQHSKEIKELENLLSQEEEENVALEEENKRALEKTNQLTEALEAIKKESFEQKAQLDSFVKSMSSLQD 2421
Cdd:pfam02463  800 EEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEEL 879

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2422 DRDRIVsDYRQLEERHLSAILEKDQLIQDAAAENNKLKEEMRGLRSHMDDLNSENAKLDAELVQYRRDLNEVIAIKDSQQ 2501
Cdd:pfam02463  880 EEQKLK-DELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEE 958

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1039751022 2502 KQLLDAQLQQNKELRN-------ECTKLEERLKGLEAEKQSLQMSSDALQKEKQGLSKEIKN 2556
Cdd:pfam02463  959 EERNKRLLLAKEELGKvnlmaieEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQRLK 1020
PTZ00121 PTZ00121
MAEBL; Provisional
 927-1655 3.79e-07

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 56.30  E-value: 3.79e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  927 ESGQEGLQQELELLRKESEQRKRKLQAALINRKELLQKVSQLEEElAKVREDSRKEIPFGENERRKLEEDRENRDDPEEW 1006
Cdd:PTZ00121  1101 EEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEA-RKAEDAKRVEIARKAEDARKAEEARKAEDAKKAE 1179

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1007 GTSKWREVEASLKQTISEKEVELEGIRRDLKEKTAAE---EELQAVVQRMTRDLQSKTKQIDLLQEEVTENQATIQKLVT 1083
Cdd:PTZ00121  1180 AARKAEEVRKAEELRKAEDARKAEAARKAEEERKAEEarkAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEE 1259

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1084 GTMDAGNGGSAAPVKETAASSPPGAGGEEHWKPElEGRILDLEKDKTQLQKKLQEALIARKAiLKKAQEKEKQ---LKEE 1160
Cdd:PTZ00121  1260 ARMAHFARRQAAIKAEEARKADELKKAEEKKKAD-EAKKAEEKKKADEAKKKAEEAKKADEA-KKKAEEAKKKadaAKKK 1337

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1161 LREQKDAYHHLQGQFHEQNKEKENIADQLRQLQCQARESIDRQLPGTGQQEPGPPAPSLEGISLEDTEPASESDLHAAQP 1240
Cdd:PTZ00121  1338 AEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAK 1417

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1241 SPPGETAALQATVSVAQiqaqlkemeveKEELELKVSSIASELAKKSEEvlllqdqineqGLEIQNLKAASVEAQAHTEL 1320
Cdd:PTZ00121  1418 KKADEAKKKAEEKKKAD-----------EAKKKAEEAKKADEAKKKAEE-----------AKKAEEAKKKAEEAKKADEA 1475

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1321 LKQELESSQlkvagLEHLKTLQPELDALHKHMGQKEEEVNYLyGQLSEKEQTLTTVQTEMVEQERliKALHTQLEMQAKE 1400
Cdd:PTZ00121  1476 KKKAEEAKK-----ADEAKKKAEEAKKKADEAKKAAEAKKKA-DEAKKAEEAKKADEAKKAEEAK--KADEAKKAEEKKK 1547

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1401 HEERLKQAQVEICELKKKPTELEEETNAKQQLQRKLQAALISRKEALKENKSLQEQLSSARDAVERLTKSLADVESQVSV 1480
Cdd:PTZ00121  1548 ADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKK 1627

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1481 QNQEKDAVLGKLTILQEERDKliAEMDRFLLENQSLSGSCESLKLALGGLTEDKEKLMEELESVRSSKMAESTEWQEKHK 1560
Cdd:PTZ00121  1628 AEEEKKKVEQLKKKEAEEKKK--AEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAE 1705

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1561 ELQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQELYAKLRSTESDKREREKQLQDAEQEMEEMKEKMRKFAKSKQQki 1640
Cdd:PTZ00121  1706 ELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEE-- 1783

                          730
                   ....*....|....*
gi 1039751022 1641 lELEEENDRLRAEAQ 1655
Cdd:PTZ00121  1784 -ELDEEDEKRRMEVD 1797
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 9-272 1.38e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 54.56  E-value: 1.38e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022    9 ESTQEDALHRLAEAEKLVVELKDIISQKDVQLQQKDEALQEEKKAAENKIKKIKlHAKAKIMSLNKHMEEIKTQGgaalp 88
Cdd:COG1196    252 EAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIA-RLEERRRELEERLEELEEEL----- 325

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022   89 pEAQAEELSKHNKSSTEEEMEIEKIKHELQEKEKLISSLQAQLdqSEQASQLDKSSAEMEDFVLMKQQLQEKEELISTLQ 168
Cdd:COG1196    326 -AELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEAL--LEAEAELAEAEEELEELAEELLEALRAAAELAAQL 402

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  169 TQLSQTQAEQAAQLSSMQQVVREKDARFETQVRLHEDELLQLVTQSDVETEMQQKLRVMQRKLEEHEEALLGRAQVVDLL 248
Cdd:COG1196    403 EELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAEL 482

                          250       260
                   ....*....|....*....|....
gi 1039751022  249 QKELTSAEQRNQVLSQQLQLLEAE 272
Cdd:COG1196    483 LEELAEAAARLLLLLEAEADYEGF 506
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1293-1735 1.84e-06

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 53.97  E-value: 1.84e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1293 LQDQINEQGLEIQNL----KAASVEAQAHTEllkQELESSQLKVAGLEHLKTLQPELDALHKHMGQKEEEVNYLYGQLSE 1368
Cdd:pfam15921  417 LRRELDDRNMEVQRLeallKAMKSECQGQME---RQMAAIQGKNESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLES 493

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1369 KEQTLTTVQTEMVEQERLIKALHTQLEMQAKEHEERLKQAQveicelkkkptELEEETNAKQQLQRKLQAALISRKEALK 1448
Cdd:pfam15921  494 SERTVSDLTASLQEKERAIEATNAEITKLRSRVDLKLQELQ-----------HLKNEGDHLRNVQTECEALKLQMAEKDK 562

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1449 ENKSLQEQLSSARDAV---ERLTKSLADVESQVSVQNQEKDAVLGKLTILQEERDKLIAEmdrflLENQSLSGSCESLKL 1525
Cdd:pfam15921  563 VIEILRQQIENMTQLVgqhGRTAGAMQVEKAQLEKEINDRRLELQEFKILKDKKDAKIRE-----LEARVSDLELEKVKL 637

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1526 ALGGltEDKEKLMEELESVRSSKMAESTEWQEKHKELQKEYEVLLQSYENVSNEAERIQHvvesvrqekqELYAKLRSTE 1605
Cdd:pfam15921  638 VNAG--SERLRAVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMETTTN----------KLKMQLKSAQ 705

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1606 SDKREREKQLQDAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEAQPVGGTGESMEALLSSNSSLKEELEKITLEH 1685
Cdd:pfam15921  706 SELEQTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATEK 785

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1686 KTLSKEFEALMAEKDALSEETRNLKLQVEAQVLKQASLEATEKSDEPKDV 1735
Cdd:pfam15921  786 NKMAGELEVLRSQERRLKEKVANMEVALDKASLQFAECQDIIQRQEQESV 835
PTZ00121 PTZ00121
MAEBL; Provisional
 676-1191 8.47e-06

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 52.07  E-value: 8.47e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  676 EKVKEISSLTQLSEEVKESAEEARSTLAAVTEERDQLLYQVKELDVLAELRARVQELEsslaEAEKQRGLDyESQRAQHN 755
Cdd:PTZ00121  1227 EAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELK----KAEEKKKAD-EAKKAEEK 1301

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  756 LLTEQIHSLSIEAKSKD---VKIEALQRELDGVQLQFCEQGTQMKTLQSQLEAKEREVREGTERlrdisQEMEGLSQALS 832
Cdd:PTZ00121  1302 KKADEAKKKAEEAKKADeakKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEK-----AEAAEKKKEEA 1376

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  833 QKELEIAKMDQlllEKQKDVETLQQTIQEKDQQVTELSFSMTEKmvQLNEEKFSLGVEIKT---LKEQLNLLSRTEEATK 909
Cdd:PTZ00121  1377 KKKADAAKKKA---EEKKKADEAKKKAEEDKKKADELKKAAAAK--KKADEAKKKAEEKKKadeAKKKAEEAKKADEAKK 1451

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  910 EQVEESGAGSSLKLGHDESGQEGLQQELELLRKESEQRKRKLQAalinrKELLQKVSQLEEELAKVREDSRKEIPFGENE 989
Cdd:PTZ00121  1452 KAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEA-----KKKADEAKKAAEAKKKADEAKKAEEAKKADE 1526

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  990 RRKLEEDRENRDDPEEWGTSKWREVEASlkqtiseKEVELEGIRRDLKEKTAAEEELQAVVQRMTRDLQSKTKQIDLLQE 1069
Cdd:PTZ00121  1527 AKKAEEAKKADEAKKAEEKKKADELKKA-------EELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMK 1599

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1070 EVTENQatiqklvtgTMDAGNGGSAAPVKETAASSPPGAggEEHWKPELEGRILDLEKDKTQLQKKLQEALIARKAILKK 1149
Cdd:PTZ00121  1600 LYEEEK---------KMKAEEAKKAEEAKIKAEELKKAE--EEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAK 1668

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|..
gi 1039751022 1150 AQEKEKQLKEELREQKDAYHHLQGQFHEQNKEKENiADQLRQ 1191
Cdd:PTZ00121  1669 KAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKK-AEELKK 1709
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2738-3016 1.75e-05

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 50.71  E-value: 1.75e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2738 ENVLSRLEKLNQQLTSKDEQLLHLSSELESSHNQVQSISKAMTSLQNERDRLWSELEKFRKSEEGKQRaaapsaasspaE 2817
Cdd:COG1196    235 RELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQ-----------D 303

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2818 VQSLKKAMSSLQNDRDRLLKELKNLQQQYLQMSQEMTELRPLKAQLQESQDQTKALQVMEEELRQENLSWQHELRQLRME 2897
Cdd:COG1196    304 IARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEE 383

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2898 KNSWELHERRMKEQFLMAISDKDQQLGHLQSLLRELRSSSQAQILSTQYQRQASPETSASLDGSQKLVYETELLRTQLND 2977
Cdd:COG1196    384 LAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLE 463

                          250       260       270
                   ....*....|....*....|....*....|....*....
gi 1039751022 2978 SLKEIHQKELRIQQLNSKFSQLLEEKNVLSTQLSDASQS 3016
Cdd:COG1196    464 LLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEAD 502
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 2439-3019 7.42e-05

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 48.68  E-value: 7.42e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2439 SAILEKDQLIQDAAAENNKLKEEMRGLRSHM----DDLNSENAKLDAELVQYRRDLNEViaikDSQQKQLLDAQLQQNK- 2513
Cdd:pfam12128  269 SDETLIASRQEERQETSAELNQLLRTLDDQWkekrDELNGELSAADAAVAKDRSELEAL----EDQHGAFLDADIETAAa 344

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2514 ------ELRNECTKLEERLKGLEAEKQSLQMSSDAL-QKEKQGLSKEIKNLQTQLTALQEEGTLG------VYHAQLKAK 2580
Cdd:pfam12128  345 dqeqlpSWQSELENLEERLKALTGKHQDVTAKYNRRrSKIKEQNNRDIAGIKDKLAKIREARDRQlavaedDLQALESEL 424

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2581 EEELQRLNMALSSSQKRTADLEEELVCVQKEATRKVSEIEDQLKK--ELKHLHHDAGIMRNETETA--EERVAELARD-- 2654
Cdd:pfam12128  425 REQLEAGKLEFNEEEYRLKSRLGELKLRLNQATATPELLLQLENFdeRIERAREEQEAANAEVERLqsELRQARKRRDqa 504

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2655 ---LVEMEQKLLTVTKENKDLMAQIqaFGRSMSSLQDSRDHATEELGDLKKKYDASLKELAQLKEWQDSSREGDVLSQAA 2731
Cdd:pfam12128  505 seaLRQASRRLEERQSALDELELQL--FPQAGTLLHFLRKEAPDWEQSIGKVISPELLHRTDLDPEVWDGSVGGELNLYG 582

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2732 FPLSTSENVLSRLEKLNQQLTSKDEQllhLSSELESSHNQVQSISKAMTSLQNERDRLWSELEkfrkseegkqraaapsa 2811
Cdd:pfam12128  583 VKLDLKRIDVPEWAASEEELRERLDK---AEEALQSAREKQAAAEEQLVQANGELEKASREET----------------- 642

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2812 asspaevqslkKAMSSLQNDRDRlLKELKNLQQQYLQMSQEMTELRPLKAQlQESQDQTKALQVMEEELRQENLSWQHEL 2891
Cdd:pfam12128  643 -----------FARTALKNARLD-LRRLFDEKQSEKDKKNKALAERKDSAN-ERLNSLEAQLKQLDKKHQAWLEEQKEQK 709

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2892 RQLRMEKNswelherrmkEQFLMAISDKDQQLGHLQSLLRELRSSSQAQI--LSTQYQRQAspetsASLDGSQKLVYETE 2969
Cdd:pfam12128  710 REARTEKQ----------AYWQVVEGALDAQLALLKAAIAARRSGAKAELkaLETWYKRDL-----ASLGVDPDVIAKLK 774

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1039751022 2970 LLRTQLNDSLKEIHQKELRIQQLNSKF-SQLLEEKNVLSTQLSDASQSLRE 3019
Cdd:pfam12128  775 REIRTLERKIERIAVRRQEVLRYFDWYqETWLQRRPRLATQLSNIERAISE 825
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1672-1883 5.63e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.14  E-value: 5.63e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1672 SSLKEELEKITLEHKTLSKEFEALMAEKDALSEETRNLKLQVEA--QVLKQASLEATEKSDEPKDVIEEVTQAVVGKSQE 1749
Cdd:COG4942     23 AEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAAlaRRIRALEQELAALEAELAELEKEIAELRAELEAQ 102

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1750 RDALSDSAKledsEAILMGDGAKPGV---SETFSSHDDIKNYLQQL-DQLKGRIAELEMEKQKDRELSQALENEKNALLT 1825
Cdd:COG4942    103 KEELAELLR----ALYRLGRQPPLALllsPEDFLDAVRRLQYLKYLaPARREQAEELRADLAELAALRAELEAERAELEA 178

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1039751022 1826 QISAKDSELKLLEEEVTKRTTLNQQIQEELcrvtKLKETAEEEKDDLEERLMNQLAEL 1883
Cdd:COG4942    179 LLAELEEERAALEALKAERQKLLARLEKEL----AELAAELAELQQEAEELEALIARL 232
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 115-404 5.67e-04

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 45.83  E-value: 5.67e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  115 HELQEKEKLISSLQAQLDQSEQA-----SQLDKSSAEMEDFVLMKQQLQEKE----ELISTLQTQLSQTQAEQAAQLSSM 185
Cdd:TIGR02169  681 ERLEGLKRELSSLQSELRRIENRldelsQELSDASRKIGEIEKEIEQLEQEEeklkERLEELEEDLSSLEQEIENVKSEL 760

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  186 QQVVREKDARFETQVRLHE-------DELLQLVTQSDVETEMQQKLRVMQRK-LEEHEEALLGRAQVVDLLQKELTSAEQ 257
Cdd:TIGR02169  761 KELEARIEELEEDLHKLEEalndleaRLSHSRIPEIQAELSKLEEEVSRIEArLREIEQKLNRLTLEKEYLEKEIQELQE 840

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  258 RNQVLSQQLQLLEAEHNTLKNTMETERQESKTL----------MEKVELEVAERKLSFHNLQEEMHQLQGQLERAGQAQA 327
Cdd:TIGR02169  841 QRIDLKEQIKSIEKEIENLNGKKEELEEELEELeaalrdlesrLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLS 920

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  328 DLETQYSALQQRHKT------EMEEKTACILSL---QKNEQELQSACAALKEENSKL-------------LQEKHDQAAE 385
Cdd:TIGR02169  921 ELKAKLEALEEELSEiedpkgEDEEIPEEELSLedvQAELQRVEEEIRALEPVNMLAiqeyeevlkrldeLKEKRAKLEE 1000

                          330
                   ....*....|....*....
gi 1039751022  386 SAQAMRQLEDQLQQKSKEI 404
Cdd:TIGR02169 1001 ERKAILERIEEYEKKKREV 1019
PRK11281 PRK11281
mechanosensitive channel MscK;
116-337 1.42e-03

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 44.52  E-value: 1.42e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  116 ELQEKEKLISSLQAQLDQSEQASQLDKSSAEMEDFVLMKQ-QLQEKEE-------LISTLQTQLSQTQAEQAAQLSSMQQ 187
Cdd:PRK11281    95 KLRQAQAELEALKDDNDEETRETLSTLSLRQLESRLAQTLdQLQNAQNdlaeynsQLVSLQTQPERAQAALYANSQRLQQ 174

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  188 VVREKDARFETQVRLHEDELLQLVTQS---DVETEMQQKL----RVMQRKLEEHEEALLGRAQV----VDLLQ-----KE 251
Cdd:PRK11281   175 IRNLLKGGKVGGKALRPSQRVLLQAEQallNAQNDLQRKSlegnTQLQDLLQKQRDYLTARIQRlehqLQLLQeainsKR 254

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  252 LTSAEQRNQVLSQQLQLLEAEHNTL-KNTMETERQESKTLMEKVELEVAerkLSFHNLQeemhqLQGQLERAGQAQADLE 330
Cdd:PRK11281   255 LTLSEKTVQEAQSQDEAARIQANPLvAQELEINLQLSQRLLKATEKLNT---LTQQNLR-----VKNWLDRLTQSERNIK 326


                   ....*..
gi 1039751022  331 TQYSALQ 337
Cdd:PRK11281   327 EQISVLK 333
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
2513-2998 4.49e-03

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 42.74  E-value: 4.49e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2513 KELRNECTKLEERLKGLEAEKQSLQMSSDALQKEKQGLSKEIKNLQTQLTALQEE-GTLGVYHAQLKAKEEELQRLNMAL 2591
Cdd:PRK03918   168 GEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREElEKLEKEVKELEELKEEIEELEKEL 247

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2592 SSSQKRTADLEEELVCVQKEATRKVSEIEDqLKKELKHLhhdagimrNETETAEERVAELARDLVEMEQKLLTVTKENKD 2671
Cdd:PRK03918   248 ESLEGSKRKLEEKIRELEERIEELKKEIEE-LEEKVKEL--------KELKEKAEEYIKLSEFYEEYLDELREIEKRLSR 318

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2672 LMAQIQAFGRSMSSLQDSRdhatEELGDLKKKYDASLKELAQLKEWQDSSREGDVLSQAAFPLSTSENVLSrLEKLNQQL 2751
Cdd:PRK03918   319 LEEEINGIEERIKELEEKE----ERLEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLT-PEKLEKEL 393

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2752 TSKDEQLLHLSSELESshnqvqsISKAMTSLQNERDRLWSELEKFRKSE--------EGKQRAAAPSAASSPAEVQSLKK 2823
Cdd:PRK03918   394 EELEKAKEEIEEEISK-------ITARIGELKKEIKELKKAIEELKKAKgkcpvcgrELTEEHRKELLEEYTAELKRIEK 466

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2824 AMSSLQNDRDRLLKELKNLQQQyLQMSQEMTELRPLKAQLQESQDQTKALQVME--------EELRQENLSWQHELRQLR 2895
Cdd:PRK03918   467 ELKEIEEKERKLRKELRELEKV-LKKESELIKLKELAEQLKELEEKLKKYNLEElekkaeeyEKLKEKLIKLKGEIKSLK 545

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2896 MEKNSWELHERRmKEQFLMAISDKDQQLGHLQSLLRELRSSSQAQI------LSTQYQR-----QASPETSASLDGSQKL 2964
Cdd:PRK03918   546 KELEKLEELKKK-LAELEKKLDELEEELAELLKELEELGFESVEELeerlkeLEPFYNEylelkDAEKELEREEKELKKL 624

                          490       500       510
                   ....*....|....*....|....*....|....
gi 1039751022 2965 VYETELLRTQLNDSLKEIHQKELRIQQLNSKFSQ 2998
Cdd:PRK03918   625 EEELDKAFEELAETEKRLEELRKELEELEKKYSE 658
 
Name Accession Description Interval E-value
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1792-2716 6.44e-20

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 98.21  E-value: 6.44e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1792 LDQLKGRIAELE-----MEKQKDR-ELSQALENEKNALLTQISAKDselklLEEEVTKRTTLNQQIQEelcrVTKLKETA 1865
Cdd:TIGR02168  188 LDRLEDILNELErqlksLERQAEKaERYKELKAELRELELALLVLR-----LEELREELEELQEELKE----AEEELEEL 258

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1866 EEEKDDLEErlmnQLAELNGSIGNYYQDVTDAQIKNEQLESEMRNLQRCVSELEEEKQQLVKEKTKVESEIRKeymekiq 1945
Cdd:TIGR02168  259 TAELQELEE----KLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEE------- 327

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1946 gaqkgpaNKSHAKELQELLREKQQEVKQLQKDCIRYLERISALEKTVKALEFVHTESQKDLDVTKGNLAQAVEHRKKAQA 2025
Cdd:TIGR02168  328 -------LESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNN 400

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2026 ELSSFKILLDDTQSEAARVLADNLKLKKELQSNKesiksqikqkdedlLRRLEQAEEKHRKEKKNMQEKLDALHREKAHV 2105
Cdd:TIGR02168  401 EIERLEARLERLEDRRERLQQEIEELLKKLEEAE--------------LKELQAELEELEEELEELQEELERLEEALEEL 466

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2106 EETLAEIQVSLTRKDQEMKELQGSLDStlaqlaafTKSMSSLQDDRDRVIDEAKKWERRFGDAIQTKEE--EVRLKEENC 2183
Cdd:TIGR02168  467 REELEEAEQALDAAERELAQLQARLDS--------LERLQENLEGFSEGVKALLKNQSGLSGILGVLSEliSVDEGYEAA 538

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2184 IALKDQLRQMAIHMEELKITVSRLEHDKEIWESKAqTELQHHQKAYDKLQEENKELTSQLEDARQLYHDSKNELTKLESE 2263
Cdd:TIGR02168  539 IEAALGGRLQAVVVENLNAAKKAIAFLKQNELGRV-TFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKA 617

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2264 LKSLKDQ---TTDLNNSLEKCKehENNLEGIIKQQEADIQNCKFsceqletdlaasreltsrlhdeinakeqkIISLLSG 2340
Cdd:TIGR02168  618 LSYLLGGvlvVDDLDNALELAK--KLRPGYRIVTLDGDLVRPGG-----------------------------VITGGSA 666

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2341 KEEAIQLAVEelhqqhsKEIKELENLLSQEEEENVALEEENKRALEKTNQLTEALEAIKKESFEQKAQLDSFVKSMSSLq 2420
Cdd:TIGR02168  667 KTNSSILERR-------REIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARL- 738

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2421 ddrdrivsdyRQLEERHLSAILEKDQLIQDAAAENNKLKEEMRGLRSHMDDLNSENAKLDAELVQYRRDLNEVIAIKDSQ 2500
Cdd:TIGR02168  739 ----------EAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDEL 808

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2501 QKQLldaqlqqnKELRNECTKLEERLKGLEAEKQSLQMSSDALQKEKQGLSKEIKNLQTQLTALQEEGTlgVYHAQLKAK 2580
Cdd:TIGR02168  809 RAEL--------TLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIE--ELESELEAL 878

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2581 EEELQRLNMALSSSQKRTADLEEELvcvqKEATRKVSEIEDQ---LKKELKHLHHDAGIMRNETETAEERVAELARDLVE 2657
Cdd:TIGR02168  879 LNERASLEEALALLRSELEELSEEL----RELESKRSELRREleeLREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLE 954

                          890       900       910       920       930       940
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2658 M-EQKLLTVTKENKDLMAQIQAFGRSMSSLQDSRDHATEELGDLKKKYDASLKELAQLKE 2716
Cdd:TIGR02168  955 EaEALENKIEDDEEEARRRLKRLENKIKELGPVNLAAIEEYEELKERYDFLTAQKEDLTE 1014
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2062-2874 5.69e-19

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 95.12  E-value: 5.69e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2062 IKSQIKQKDEDLL-RRLEQAEEKHR---KEKKNMQEKLDALHREKAHVEETLAEIQVSLTRKDQEMKELQGSLDSTLAQL 2137
Cdd:TIGR02168  218 LKAELRELELALLvLRLEELREELEelqEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEI 297

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2138 AAFTKSMSSLQDDRDRVIDEAKKWERRFGDAIQTKEEevrlKEENCIALKDQLRQMAIHMEELKITVSRLEHDKEIWESK 2217
Cdd:TIGR02168  298 SRLEQQKQILRERLANLERQLEELEAQLEELESKLDE----LAEELAELEEKLEELKEELESLEAELEELEAELEELESR 373

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2218 aqtelqhhqkaydklqeeNKELTSQLEDARQLYHDSKNELTKLESELKSLKDQTTDLNNSLEKckEHENNLEGIIKQQEA 2297
Cdd:TIGR02168  374 ------------------LEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRER--LQQEIEELLKKLEEA 433

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2298 DIQNCKFSCEQLETDLAasrELTSRLhDEINAKEQKIISLLSGKEEAIQLAVEELhQQHSKEIKELENLLSQEEEENVAL 2377
Cdd:TIGR02168  434 ELKELQAELEELEEELE---ELQEEL-ERLEEALEELREELEEAEQALDAAEREL-AQLQARLDSLERLQENLEGFSEGV 508

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2378 EEENKRALEKTNQLTEALEAIKKESFEQKAQLDSFVKSMSSLQDDRD----RIVSDYRQLEERHLSAILEKDQLIQDAAA 2453
Cdd:TIGR02168  509 KALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGRLQAVVVENLnaakKAIAFLKQNELGRVTFLPLDSIKGTEIQG 588

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2454 ENNKLKEEMRGLRSHMDDLNSENAKLDAeLVQYRrdLNEVIAIKDsqqkqlLDAQLQQNKELRnectkLEERLKGLEAE- 2532
Cdd:TIGR02168  589 NDREILKNIEGFLGVAKDLVKFDPKLRK-ALSYL--LGGVLVVDD------LDNALELAKKLR-----PGYRIVTLDGDl 654

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2533 ---KQSLQMSSDALQKEKQGLSKEIKNLQTQLTALQEEGTLGvyHAQLKAKEEELQRLNMALSSSQKRTADLEEELVCVQ 2609
Cdd:TIGR02168  655 vrpGGVITGGSAKTNSSILERRREIEELEEKIEELEEKIAEL--EKALAELRKELEELEEELEQLRKELEELSRQISALR 732

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2610 KEATRKVSEIEdQLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLTVTKENKDLMAQIQAFGRSMSSLQds 2689
Cdd:TIGR02168  733 KDLARLEAEVE-QLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELR-- 809

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2690 rdhatEELGDLKKKYDASLKELAQL-KEWQDSSREGDVLSQaafplsTSENVLSRLEKLNQQLTSKDEQLLHLSSELESS 2768
Cdd:TIGR02168  810 -----AELTLLNEEAANLRERLESLeRRIAATERRLEDLEE------QIEELSEDIESLAAEIEELEELIEELESELEAL 878

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2769 HNQVQSISKAMTSLQNERDrlwsELEKFRKSEEGKQRAAAPSAASSPAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQ 2848
Cdd:TIGR02168  879 LNERASLEEALALLRSELE----ELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLE 954

                          810       820
                   ....*....|....*....|....*.
gi 1039751022 2849 MSQEMTELRPlkAQLQESQDQTKALQ 2874
Cdd:TIGR02168  955 EAEALENKIE--DDEEEARRRLKRLE 978
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 274-999 1.17e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 93.97  E-value: 1.17e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  274 NTLKNTMETERQESKTLMEKVELEVAERKLSFHNLQEEMHQLQGQLERAGQAQADLETQYSALQQRHK---TEMEEKTAC 350
Cdd:TIGR02168  245 QEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLAnleRQLEELEAQ 324

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  351 ILSLQKNEQELQSACAALKEENSKLLQEKHDQAA---ESAQAMRQLEDQLQQKSKEISQFVNKPNLQKNETASQTSlpdv 427
Cdd:TIGR02168  325 LEELESKLDELAEELAELEEKLEELKEELESLEAeleELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNN---- 400

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  428 nnegDQAVMEETVASLQKRVVELENEKGALL---------LSSGELEELKAENEKLSSRitLLEAQNRAGEADGTVCEVS 498
Cdd:TIGR02168  401 ----EIERLEARLERLEDRRERLQQEIEELLkkleeaelkELQAELEELEEELEELQEE--LERLEEALEELREELEEAE 474

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  499 TAGTTLLNRSDSSpeENGQAVLENTFsQKHKELSVLLVEMKEAQEEIAFLKSQL-QGKRPEGDYE--------------V 563
Cdd:TIGR02168  475 QALDAAERELAQL--QARLDSLERLQ-ENLEGFSEGVKALLKNQSGLSGILGVLsELISVDEGYEaaieaalggrlqavV 551

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  564 LDRREVQLMESEGPPSVTAGDVLCAPSDESSGPAAEEEQAGMKDRHRaSEAGPLNDagMELSSPKLDGV-DKSLAVSHVC 642
Cdd:TIGR02168  552 VENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIE-GFLGVAKD--LVKFDPKLRKAlSYLLGGVLVV 628

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  643 QCHQGELERLKTqvLELETSLHTAE------------ETYKRNLS--EKVKEISSLTQLSEEVKESAEEARSTLAAVTEE 708
Cdd:TIGR02168  629 DDLDNALELAKK--LRPGYRIVTLDgdlvrpggvitgGSAKTNSSilERRREIEELEEKIEELEEKIAELEKALAELRKE 706

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  709 RDQLlyqvkeLDVLAELRARVQELESSLAEAEKqrglDYESQRAQHNLLTEQIHSLSIEAKSKDVKIEALQRELDGVQLQ 788
Cdd:TIGR02168  707 LEEL------EEELEQLRKELEELSRQISALRK----DLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEE 776

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  789 FCEQGTQMKTLQSQLEAKEREVREGTERLRDISQEMEGLSQALSQKELEIAKMDQLLLEKQKDVETLQQTIQEKDQQVTE 868
Cdd:TIGR02168  777 LAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIES 856

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  869 LSFSMTEKMVQLNEEKfslgveiKTLKEQLNLLSRTEEATKEQVEESGAgSSLKLGHDESGQEGLQQELELLRKESEQRK 948
Cdd:TIGR02168  857 LAAEIEELEELIEELE-------SELEALLNERASLEEALALLRSELEE-LSEELRELESKRSELRRELEELREKLAQLE 928

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1039751022  949 RKLQAALINRKELLQKVS---QLEEELAKVREDSRKEIPFG-ENERRKLEEDREN 999
Cdd:TIGR02168  929 LRLEGLEVRIDNLQERLSeeySLTLEEAEALENKIEDDEEEaRRRLKRLENKIKE 983
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 692-1597 9.87e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 91.27  E-value: 9.87e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  692 KESAEEARSTLAAVTEERDQLLyqvkelDVLAELRARVQELESSLAEAEKQRGLDYESQRAQHNLLTEQIHSLsieaksk 771
Cdd:TIGR02168  171 KERRKETERKLERTRENLDRLE------DILNELERQLKSLERQAEKAERYKELKAELRELELALLVLRLEEL------- 237

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  772 DVKIEALQRELDGVQLQFCEQGTQMKTLQSQLEAKEREVREGTERLRDISQEMEGLSQALSQKELEIAKMDQLLLEKQKD 851
Cdd:TIGR02168  238 REELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQ 317

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  852 VETLQQTIQEKDQQVTElsfsmtekmvqLNEEKFSLGVEIKTLKEQLNLLSRTEEATKEQVEESgagsslklghdESGQE 931
Cdd:TIGR02168  318 LEELEAQLEELESKLDE-----------LAEELAELEEKLEELKEELESLEAELEELEAELEEL-----------ESRLE 375

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  932 GLQQELELLRKESEQRKRKLQAALINRKELLQKVSQLEEELAkvredsrkeipfgenerRKLEEDRENRDDPEEWGTSKW 1011
Cdd:TIGR02168  376 ELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRE-----------------RLQQEIEELLKKLEEAELKEL 438

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1012 REVEASLKQTISEKEVELEGIRRDLKEKTAAEEELQAVVQRMTRDLQSKTKQIDLLqEEVTENQATIQKLVTGTMDAGNG 1091
Cdd:TIGR02168  439 QAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSL-ERLQENLEGFSEGVKALLKNQSG 517

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1092 GSA-APVKETAASSPPGaggeehWKPELE----GRILDLEKDKTQLQKKLQEALiarkailkKAQEKEKQLKEELREQKD 1166
Cdd:TIGR02168  518 LSGiLGVLSELISVDEG------YEAAIEaalgGRLQAVVVENLNAAKKAIAFL--------KQNELGRVTFLPLDSIKG 583

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1167 AyhHLQGQFHEQNKEKENIADQLRQLqcqarESIDRQLPGTGQqepgppaPSLEGISLEDTepaSESDLHAAQPSPPGET 1246
Cdd:TIGR02168  584 T--EIQGNDREILKNIEGFLGVAKDL-----VKFDPKLRKALS-------YLLGGVLVVDD---LDNALELAKKLRPGYR 646

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1247 AALQATVSVAQIQAQLKEMEVEKEELELKVssiaSELAKKSEEVLLLQDQINEQGLEIQNLKAASVEAQAHTELLKQELE 1326
Cdd:TIGR02168  647 IVTLDGDLVRPGGVITGGSAKTNSSILERR----REIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELE 722

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1327 SSQLKVAGL-EHLKTLQPELDALHKHMGQKEEEVNYLYGQLSEKEQTLTTVQTEMVEQERLIKalhtQLEMQAKEHEERL 1405
Cdd:TIGR02168  723 ELSRQISALrKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIE----ELEAQIEQLKEEL 798

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1406 KQAQVEICELKKKPTELEEE----TNAKQQLQRKLQAALISRKEALKENKSLQEQLSSARDAVERLTKSLADVESQVSVQ 1481
Cdd:TIGR02168  799 KALREALDELRAELTLLNEEaanlRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEAL 878

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1482 NQEKDAVLGKLTILQEERDKLIAEMDRFLLENQSLSGSCESLKLALGGLTEDKEKLMEELESVRSSKMAestewqekhkE 1561
Cdd:TIGR02168  879 LNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSE----------E 948

                          890       900       910
                   ....*....|....*....|....*....|....*.
gi 1039751022 1562 LQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQEL 1597
Cdd:TIGR02168  949 YSLTLEEAEALENKIEDDEEEARRRLKRLENKIKEL 984
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1293-2126 3.78e-17

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 89.35  E-value: 3.78e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1293 LQDQINEQGLEIQNLKAASVEAQAHTELlKQELESSQLKVAGLEhLKTLQPELDALHKHMGQKEEEVNYLYGQLSEKEQT 1372
Cdd:TIGR02168  191 LEDILNELERQLKSLERQAEKAERYKEL-KAELRELELALLVLR-LEELREELEELQEELKEAEEELEELTAELQELEEK 268

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1373 LTTVQTEMVEQERLIKALHTQL----------EMQAKEHEERL-------KQAQVEICELKKKPTELEEETNAKQQLQRK 1435
Cdd:TIGR02168  269 LEELRLEVSELEEEIEELQKELyalaneisrlEQQKQILRERLanlerqlEELEAQLEELESKLDELAEELAELEEKLEE 348

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1436 LQAALISRKEALKE-----------NKSLQEQLSSARDAVERLTKSLADVESQVSVQNQEKDAVLGKLTILQEERDKLIA 1504
Cdd:TIGR02168  349 LKEELESLEAELEEleaeleelesrLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLK 428

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1505 EMDRflLENQSLSGSCESLKLALggltedkeklmeelesvrsskmaestewqekhKELQKEYEVLLQSYENVSNEAERIQ 1584
Cdd:TIGR02168  429 KLEE--AELKELQAELEELEEEL--------------------------------EELQEELERLEEALEELREELEEAE 474

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1585 HVVESVRQEKQELYAKLRSTESDKREREKQLQDAEQEMEEMKEKMRKFAKSKQQkiLELEEENDRLRAEAqpvggTGESM 1664
Cdd:TIGR02168  475 QALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSEL--ISVDEGYEAAIEAA-----LGGRL 547

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1665 EALLSSNSSLKEELEKITLEHKTLSKEFEALMAEKDALSEETRNLKLQVEAQVLKQASLEATEKSDEPKDVIEEVTQAVV 1744
Cdd:TIGR02168  548 QAVVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLV 627

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1745 GKSQErDALSDSAKLEDSEAI------------LMGDGAKPGVSETFSSHDDIKNYLQQLDQLKGRIAELEMEKQKDREL 1812
Cdd:TIGR02168  628 VDDLD-NALELAKKLRPGYRIvtldgdlvrpggVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKE 706

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1813 SQALENE-------KNALLTQISAKDSELKLLEEEVTKRTTLNQQIQEELCRVTKLKETAEEEKDDLEErlmnQLAELNG 1885
Cdd:TIGR02168  707 LEELEEEleqlrkeLEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEE----ELAEAEA 782

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1886 SIGNYYQDVTDAQIKNEQLESEMRNLQRCVSELEEEKQQLVKEKTKVESEIRKEYMEKIQGAQKGPANKSHAKELQELLR 1965
Cdd:TIGR02168  783 EIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIE 862

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1966 EKQQEVKQLQKDCIRYLERISALEKTVKALEFVHTESQKDLDVT-------KGNLAQAVEHRKKAQAELSSFKILLDDTQ 2038
Cdd:TIGR02168  863 ELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELeskrselRRELEELREKLAQLELRLEGLEVRIDNLQ 942

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2039 SEAARVLADNLKLKKELQSNKESIKSQIKQKDEDLLRRLEQ-------AEEKHRKEKknmqEKLDALHREKAHVEETLAE 2111
Cdd:TIGR02168  943 ERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKElgpvnlaAIEEYEELK----ERYDFLTAQKEDLTEAKET 1018

                          890
                   ....*....|....*
gi 1039751022 2112 IQVSLTRKDQEMKEL 2126
Cdd:TIGR02168 1019 LEEAIEEIDREARER 1033
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1788-2557 1.39e-16

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 87.42  E-value: 1.39e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1788 YLQQLDQLKGRIAELEMEKQKDRELSQALENEKNALLTQISAKDSELKLLEEEVTKRTTLNQQIQEELCRVTKLKETAEE 1867
Cdd:TIGR02168  230 LVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRE 309

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1868 EKDDLEerlmNQLAELNGSIgnyyqdvtdaqiknEQLESEMRNLQRCVSELEEEKQQLVKEKTKVESEIRKEYMEKiqga 1947
Cdd:TIGR02168  310 RLANLE----RQLEELEAQL--------------EELESKLDELAEELAELEEKLEELKEELESLEAELEELEAEL---- 367

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1948 qkgPANKSHAKELQELLREKQQEVKQLQKDCIRYLERISALEKTVKALEfvhTESQKDLDVTKGNLAQAVEHRKKA-QAE 2026
Cdd:TIGR02168  368 ---EELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLE---DRRERLQQEIEELLKKLEEAELKElQAE 441

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2027 LSSFKILLDDTQSEAARVLADNLKLKKELQSNKESIKS------QIKQKDEDLLRRLEQAEEKHRKEKKNMQEKL----- 2095
Cdd:TIGR02168  442 LEELEEELEELQEELERLEEALEELREELEEAEQALDAaerelaQLQARLDSLERLQENLEGFSEGVKALLKNQSglsgi 521

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2096 -----DALHREK---AHVEETLAE-IQVSLTRKDQEMKELQGSLDSTLAQLAAF------------------TKSMSSLQ 2148
Cdd:TIGR02168  522 lgvlsELISVDEgyeAAIEAALGGrLQAVVVENLNAAKKAIAFLKQNELGRVTFlpldsikgteiqgndreiLKNIEGFL 601

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2149 DDRDRVIDEAKKWERRFG---------DAIQTKEEEVRL--KEENCIALKDQL--RQMAIHMEELKITVSRLEHDKEIWE 2215
Cdd:TIGR02168  602 GVAKDLVKFDPKLRKALSyllggvlvvDDLDNALELAKKlrPGYRIVTLDGDLvrPGGVITGGSAKTNSSILERRREIEE 681

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2216 SKAQTElqhhqkaydKLQEENKELTSQLEDARQLYHDSKNELTKLESELKSLKDQTTDLNNSLEKCKEHENNLEGIIKQQ 2295
Cdd:TIGR02168  682 LEEKIE---------ELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQL 752

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2296 EADIQNCKFSCEQLETDLAASRELTSRLHDEINAKEQKIISLLS--GKEEAIQLAVEELHQQHSKEIKELENLLSQEEEE 2373
Cdd:TIGR02168  753 SKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEelKALREALDELRAELTLLNEEAANLRERLESLERR 832

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2374 NVALEEENKRALEKTNQLTEALEAIKKESFEQKAQLDSFVKSMSSLQDDRDRIvsdyRQLEERHLSAILEKDQLIQDAAA 2453
Cdd:TIGR02168  833 IAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASL----EEALALLRSELEELSEELRELES 908

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2454 ENNKLKEEMRGLRSHMDDLNSENAKLDAEL--------VQYRRDLNEVIAIKDSQQKQLLDAQlQQNKELRNECTKL--- 2522
Cdd:TIGR02168  909 KRSELRRELEELREKLAQLELRLEGLEVRIdnlqerlsEEYSLTLEEAEALENKIEDDEEEAR-RRLKRLENKIKELgpv 987

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|....*.
gi 1039751022 2523 -----------EERLKGLEAEKQSLQMSSDALQKEKQGLSKEIKNL 2557
Cdd:TIGR02168  988 nlaaieeyeelKERYDFLTAQKEDLTEAKETLEEAIEEIDREARER 1033
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1373-2276 1.50e-15

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 83.96  E-value: 1.50e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1373 LTTVQTEMVEQERLIKALHTQLEMQAKEHEERLKqaqVEICELKKKPTELEEETNAKQQLQRKLQAALISRKEALKENKS 1452
Cdd:TIGR02169  179 LEEVEENIERLDLIIDEKRQQLERLRREREKAER---YQALLKEKREYEGYELLKEKEALERQKEAIERQLASLEEELEK 255

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1453 LQEQLSSARDAVERLTKSLADVESQVS-VQNQEKDAVLGKLTILQEERDKLIAEMDRFLLENQSLSGSCESLKLALGGLT 1531
Cdd:TIGR02169  256 LTEEISELEKRLEEIEQLLEELNKKIKdLGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLL 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1532 EDKEKLMEELESVRsskmAESTEWQEKHKELQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQELYAKLrstESDKRER 1611
Cdd:TIGR02169  336 AEIEELEREIEEER----KRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREI---NELKREL 408

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1612 EKqLQDAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEAQPVGGTGESMEALLSSNSS----LKEELEKITLEHKT 1687
Cdd:TIGR02169  409 DR-LQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQelydLKEEYDRVEKELSK 487

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1688 LSKEFEALMAEKDALSEETRNLKLQVEaqvlkqasleatEKSDEPKDVIEEVTQAVVGKSQERDALSDSAkledseailm 1767
Cdd:TIGR02169  488 LQRELAEAEAQARASEERVRGGRAVEE------------VLKASIQGVHGTVAQLGSVGERYATAIEVAA---------- 545

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1768 GDGAKPGVSETfssHDDIKNYLQQLDQLK-GRIAELEMEKQKDRELSQALENEKNALltqisakDSELKLLEEEVTKRTT 1846
Cdd:TIGR02169  546 GNRLNNVVVED---DAVAKEAIELLKRRKaGRATFLPLNKMRDERRDLSILSEDGVI-------GFAVDLVEFDPKYEPA 615

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1847 LNQQIQEelcrvTKLKETAEEEKDDLEERLMNQLA----ELNGSIGNYYQDVTDAQIKNEQLESEMRNLQRCVSELEEEK 1922
Cdd:TIGR02169  616 FKYVFGD-----TLVVEDIEAARRLMGKYRMVTLEgelfEKSGAMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKREL 690

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1923 QQLVKEKTKVESEIRkeymekiqgaqkgpANKSHAKELQELLREKQQEVKQLQKDCIRYLERISALEKTVKALEFVHTES 2002
Cdd:TIGR02169  691 SSLQSELRRIENRLD--------------ELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENV 756

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2003 QKDLDVTKGNLAQAVEHRKKAQAELSSFKILLDDTQSEAARVLADnlKLKKELQSNkESIKSQIKQKDEDLLRRLEQAEE 2082
Cdd:TIGR02169  757 KSELKELEARIEELEEDLHKLEEALNDLEARLSHSRIPEIQAELS--KLEEEVSRI-EARLREIEQKLNRLTLEKEYLEK 833

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2083 khrkEKKNMQEKLDALHREKAHVEETLAEIQVSLTRKDQEMKELQgsldstlAQLAAFTKSMSSLQDDRDRVIDEAKKWE 2162
Cdd:TIGR02169  834 ----EIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELE-------AALRDLESRLGDLKKERDELEAQLRELE 902

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2163 RRfgdaIQTKEEEVRLKEENciaLKDQLRQMAIHMEELKITVSRLEHDKEIWES-----KAQTELQHHQKAYDKLQEENK 2237
Cdd:TIGR02169  903 RK----IEELEAQIEKKRKR---LSELKAKLEALEEELSEIEDPKGEDEEIPEEelsleDVQAELQRVEEEIRALEPVNM 975

                          890       900       910
                   ....*....|....*....|....*....|....*....
gi 1039751022 2238 ELTSQLEDARQLYHDSKNELTKLESELKSLKDQTTDLNN 2276
Cdd:TIGR02169  976 LAIQEYEEVLKRLDELKEKRAKLEEERKAILERIEEYEK 1014
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1785-2626 1.93e-15

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 83.58  E-value: 1.93e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1785 IKNYLQQLDQLKGRIAELEMEKQKDRELSQA----LENEKNALLTQISAKDSELKLLEEEVTKRTTLNQQIQEELCRVTK 1860
Cdd:TIGR02169  193 IDEKRQQLERLRREREKAERYQALLKEKREYegyeLLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQ 272

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1861 LKETAEEEKDDLEERLMNQLaelngsignyyqdvtdaQIKNEQLESEMRNLQRCVSELEEEKQQLVKEKTKVESEIRKEy 1940
Cdd:TIGR02169  273 LLEELNKKIKDLGEEEQLRV-----------------KEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKL- 334

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1941 mekiqgaqkgpanKSHAKELQELLREKQQEVKQLQkdcirylERISALEKTVKALEFVHTESQKDLDVTKGNLAQAVEHR 2020
Cdd:TIGR02169  335 -------------LAEIEELEREIEEERKRRDKLT-------EEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKL 394

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2021 KKAQAELSSFKILLDDTQSEAARVLADNLKLKKELqsnkESIKSQIKQKDEDLLRRLEQAEEKHRKEKKNmQEKLDALHR 2100
Cdd:TIGR02169  395 EKLKREINELKRELDRLQEELQRLSEELADLNAAI----AGIEAKINELEEEKEDKALEIKKQEWKLEQL-AADLSKYEQ 469

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2101 EKAHVEETLAEIQVSLTRKDQEMKELQGSLDSTLAQLAAFTKSMSSLQDDRDRV---IDEAKKWERRFGDAIQTK----- 2172
Cdd:TIGR02169  470 ELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVhgtVAQLGSVGERYATAIEVAagnrl 549

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2173 -----EEEVRLKEenCIALkdqLRQMAI---------HMEELKITVSRLEHDKEIWESKAQTELQHHQKAYDKLQEENKE 2238
Cdd:TIGR02169  550 nnvvvEDDAVAKE--AIEL---LKRRKAgratflplnKMRDERRDLSILSEDGVIGFAVDLVEFDPKYEPAFKYVFGDTL 624

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2239 LTSQLEDARQLYhdSKNELTKLESELKSLKDQTTDLNNSlekckehENNLEGIIKQQEADIQNCKFSCEQLETDLAASRE 2318
Cdd:TIGR02169  625 VVEDIEAARRLM--GKYRMVTLEGELFEKSGAMTGGSRA-------PRGGILFSRSEPAELQRLRERLEGLKRELSSLQS 695

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2319 LTSRLHDEINAKEQKiISLLSGKEEAIQLAVEELHQQHSK---EIKELENLLSQEEEENVALEEENKRALEKTNQLTEAL 2395
Cdd:TIGR02169  696 ELRRIENRLDELSQE-LSDASRKIGEIEKEIEQLEQEEEKlkeRLEELEEDLSSLEQEIENVKSELKELEARIEELEEDL 774

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2396 EAIKKESFEQKA-----QLDSFVKSMSSLQDDRDRIVSDYRQLEERHLSAILEKDQL---IQDAAAENNKLKEEMRGLRS 2467
Cdd:TIGR02169  775 HKLEEALNDLEArlshsRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLekeIQELQEQRIDLKEQIKSIEK 854

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2468 HMDDLNSENAKLDAELVQYRRDLNEVIAIKDSQQKQLldaqlqqnKELRNECTKLEERLKGLEAEKQSLQMSSDALQKEK 2547
Cdd:TIGR02169  855 EIENLNGKKEELEEELEELEAALRDLESRLGDLKKER--------DELEAQLRELERKIEELEAQIEKKRKRLSELKAKL 926

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2548 QGLSKEIKNLQTQLTALQEEG----TLGVYHAQLKAKEEELQRL---NMA----LSSSQKRTADLEEELVCVQKEATRKV 2616
Cdd:TIGR02169  927 EALEEELSEIEDPKGEDEEIPeeelSLEDVQAELQRVEEEIRALepvNMLaiqeYEEVLKRLDELKEKRAKLEEERKAIL 1006

                          890
                   ....*....|..
gi 1039751022 2617 SEIE--DQLKKE 2626
Cdd:TIGR02169 1007 ERIEeyEKKKRE 1018
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1443-2344 9.82e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 81.26  E-value: 9.82e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1443 RKEALKenkslqeQLSSARDAVERLTKSLADVESQV-SVQNQEKDAVlgKLTILQEERDKLiaEMDRFLLENQSLSGSCE 1521
Cdd:TIGR02168  174 RKETER-------KLERTRENLDRLEDILNELERQLkSLERQAEKAE--RYKELKAELREL--ELALLVLRLEELREELE 242

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1522 SLKLALggltEDKEKLMEELESVRSSKMAESTEWQEKHKELQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQELYAKL 1601
Cdd:TIGR02168  243 ELQEEL----KEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQL 318

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1602 RSTESDKREREKQLQDAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEAQPVGGTGESMEALLSSNSSLKEELEKI 1681
Cdd:TIGR02168  319 EELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASL 398

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1682 TLEHKTLSKEFEALMAEKDALSEETRNLKLQVEAQVLKQASLEATEKSDEPKDVIEEVTQAVVGKSQERDALS------D 1755
Cdd:TIGR02168  399 NNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEeaeqalD 478

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1756 SAKLEDSEAILMGDGAKPGVSETFSSHDDIKNYLQQLDQLKGRIAELEMEKQKDRELSQALENEKNALLTQISAKDSELK 1835
Cdd:TIGR02168  479 AAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGRLQAVVVENLNAA 558

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1836 LLEEEVTKrttlnqqiQEELCRVTKLKETAEEEkDDLEERLMNQLAELNGSIGnYYQDVTDAQIKNEQLESEMRNLQRCV 1915
Cdd:TIGR02168  559 KKAIAFLK--------QNELGRVTFLPLDSIKG-TEIQGNDREILKNIEGFLG-VAKDLVKFDPKLRKALSYLLGGVLVV 628

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1916 SELEEEKQQLVKEKTKVESEIRKEYMEKIQGAQKGPANKSHA---------KELQELLREKQQEVKQLQKDCIRYLERIS 1986
Cdd:TIGR02168  629 DDLDNALELAKKLRPGYRIVTLDGDLVRPGGVITGGSAKTNSsilerrreiEELEEKIEELEEKIAELEKALAELRKELE 708

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1987 ALEKTVKALEFVHTESQKDLDVTKGNLAQAVEHRKKAQAELSSfkilLDDTQSEAARVLADNLKLKKELQSNKESIKSQI 2066
Cdd:TIGR02168  709 ELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQ----LSKELTELEAEIEELEERLEEAEEELAEAEAEI 784

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2067 KQKDEDLLRRLEQAeEKHRKEKKNMQEKLDALHREKAHVEETLAEIQVSLTRKDQEMKELQGSLDSTLAQLAAFTKSMSS 2146
Cdd:TIGR02168  785 EELEAQIEQLKEEL-KALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEE 863

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2147 LQDDRDRVIDEAKKWerrfgdaiqtkEEEVRLKEENCIALKDQLRQMAIHMEELKITVSRLEHDKEiwesKAQTELQHHQ 2226
Cdd:TIGR02168  864 LEELIEELESELEAL-----------LNERASLEEALALLRSELEELSEELRELESKRSELRRELE----ELREKLAQLE 928

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2227 KAYDKLQEENKELTSQL--------EDARQLYHDSKNELTKLESELKSLKDQTTDLNN----SLEKCKEHENNLEGIIKQ 2294
Cdd:TIGR02168  929 LRLEGLEVRIDNLQERLseeysltlEEAEALENKIEDDEEEARRRLKRLENKIKELGPvnlaAIEEYEELKERYDFLTAQ 1008

                          890       900       910       920       930
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1039751022 2295 QEaDIQNCKFSCEQLETDLaaSRELTSRLHD---EINAKEQKIISLLSGKEEA 2344
Cdd:TIGR02168 1009 KE-DLTEAKETLEEAIEEI--DREARERFKDtfdQVNENFQRVFPKLFGGGEA 1058
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 720-1362 7.88e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 78.05  E-value: 7.88e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  720 DVLAELRARVQELESSLAEAEKQRGLDYESQRAQHNLLTEQIHSLSIEAKSKDVKIEALQRELdgvqlqfceqgtqmKTL 799
Cdd:COG1196    193 DILGELERQLEPLERQAEKAERYRELKEELKELEAELLLLKLRELEAELEELEAELEELEAEL--------------EEL 258

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  800 QSQLEAKEREVREGTERLRDISQEMEGLSQALSQKELEIAKMDQLLLEKQKDVETLQQTIQEKDQQVTELsfsmTEKMVQ 879
Cdd:COG1196    259 EAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAEL----EEELEE 334

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  880 LNEEKFSLGVEIKTLKEQLNLLSRTEEATKEQVEEsgagsslklghDESGQEGLQQELELLRKESEQRKRKLQAALINRK 959
Cdd:COG1196    335 LEEELEELEEELEEAEEELEEAEAELAEAEEALLE-----------AEAELAEAEEELEELAEELLEALRAAAELAAQLE 403

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  960 ELLQKVSQLEEELAKVREDSRKEipfgENERRKLEEDRENRddpeewgtskwREVEASLKQTISEKEVELEGIRRDLKEK 1039
Cdd:COG1196    404 ELEEAEEALLERLERLEEELEEL----EEALAELEEEEEEE-----------EEALEEAAEEEAELEEEEEALLELLAEL 468

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1040 TAAEEELQAVVQRMTRDLQSKTKQIDLLQEEVTEnqatiqklvtgtMDAGNGGSAAPVKETAASSPPGAGGEEHWKPELE 1119
Cdd:COG1196    469 LEEAALLEAALAELLEELAEAAARLLLLLEAEAD------------YEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAY 536

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1120 GRILDLEKDKTQLQKKLQEALIARKAILKKAQEKEKQLKEELREQKDAYHHLQGQFHEQNKEKENIADQLRQLQCQARES 1199
Cdd:COG1196    537 EAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYY 616

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1200 IDRQLPGTGQQEPGPPAPSLEGISLEDTEPASESDLHAAQPSPPGETAALQATVSVAQIQAQLKEMEVEKEELELKVSSI 1279
Cdd:COG1196    617 VLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELE 696

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1280 ASELAKKSEEVLLLQDQINEQGLEIQNLKAASVEAQAHTELLKQELESSQLKVAGLEHLKTLQPELDALHKHMGQKEEEV 1359
Cdd:COG1196    697 EALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREI 776


                   ...
gi 1039751022 1360 NYL 1362
Cdd:COG1196    777 EAL 779
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1365-1938 1.13e-13

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 77.67  E-value: 1.13e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1365 QLSEKEQTLTTVQTEMVEQERLIKALHTQLEMQAKEHEERLKQAQVEICELKKKPTELEE----ETNAKQQLQRKLQAAL 1440
Cdd:COG1196    243 ELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQdiarLEERRRELEERLEELE 322

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1441 ISRKEALKENKSLQEQLSSARDAVERLTKSLADVESQVSVQNQEKDAVLGKLTILQEERDKLIAEMDRFLLENQSLSGSC 1520
Cdd:COG1196    323 EELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQL 402

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1521 ESLKLALGGLTEDKEKLMEELESVRSSKMAESTEWQEKHKELQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQELYAK 1600
Cdd:COG1196    403 EELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAEL 482

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1601 LRSTESDKREREKQLQDAEQEMEEMKEKMRKFAKSKQQKILEL--EEENDRLRAEAQPVGGTGESMEALLSSNSSLKEEL 1678
Cdd:COG1196    483 LEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAvaVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAA 562

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1679 EKITLEHKTLSKEFEAL-MAEKDALSEETRNLKLQVEAQVLKQASLEATEKSDEPKDVIEEVTQAVVGKSQERDALSDSA 1757
Cdd:COG1196    563 IEYLKAAKAGRATFLPLdKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTL 642

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1758 KLEDSEAILMGDGAKPGVSETfsshddiknylqqLDQLKGRIAELEMEKQKDRELSQALENEKNALLTQISAKDSELKLL 1837
Cdd:COG1196    643 AGRLREVTLEGEGGSAGGSLT-------------GGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEEREL 709

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1838 EEEVTKRTTLNQQIQEELCRVTKLKETAEEEKDDLEERLMNQLAELNGSIgnyyQDVTDAQIKNEQLESEMRNLQRcV-- 1915
Cdd:COG1196    710 AEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEP----PDLEELERELERLEREIEALGP-Vnl 784

                          570       580
                   ....*....|....*....|....*....
gi 1039751022 1916 ------SELEEEKQQLVKEKTKVESEIRK 1938
Cdd:COG1196    785 laieeyEELEERYDFLSEQREDLEEARET 813
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 646-1220 1.55e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 73.82  E-value: 1.55e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  646 QGELERLKTQVLELETSLHTAEETYKRNLSEKVKEISSLTQLSEEVKESAEEARSTLAAVTEERDQLLYQVKELDVLAEL 725
Cdd:COG1196    238 EAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEER 317

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  726 RARVQELESSLAEAEKQRGLDYESQRAQHNLLTEQIHSLSIEAKSKDVKIEALQRELDGVQLQFCEQGTQMKTLQSQLEA 805
Cdd:COG1196    318 LEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAE 397

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  806 KEREVREGTERLRDISQEMEGLSQALSQKELEIAKMDQLLLEKQKDVETLQQTIQEKDQQVTELsfsmTEKMVQLNEEKF 885
Cdd:COG1196    398 LAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEAL----LELLAELLEEAA 473

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  886 SLGVEIKTLKEQLNLLSRTEEATKE-QVEESGAGSSLKLGHDESGQEGLQQELELLRKESEQRKRKLQAALInrkELLQK 964
Cdd:COG1196    474 LLEAALAELLEELAEAAARLLLLLEaEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALA---AALQN 550

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  965 VSQLEEELAKVREDSRKEIPFGENERRKLEEDRENRDDPeewgtskwrevEASLKQTISEKEVELEGIRRDLKEKTAAEE 1044
Cdd:COG1196    551 IVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALA-----------AALARGAIGAAVDLVASDLREADARYYVLG 619

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1045 ELQAVVQRMTRDLQSKTKQIDLLQEEVTEnqatiqklVTGTMDAGNGGSAapvketaassppgaggeehwkpelEGRILD 1124
Cdd:COG1196    620 DTLLGRTLVAARLEAALRRAVTLAGRLRE--------VTLEGEGGSAGGS------------------------LTGGSR 667

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1125 LEKDKTQLQKKLQEALIARKAILKKAQEKEKQLKEELREQKDAYHHLQGQFHEQNKEKENIADQLRQLQCQARESIDRQL 1204
Cdd:COG1196    668 RELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEEL 747

                          570
                   ....*....|....*.
gi 1039751022 1205 PGTGQQEPGPPAPSLE 1220
Cdd:COG1196    748 LEEEALEELPEPPDLE 763
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1957-2557 2.66e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 73.05  E-value: 2.66e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1957 AKELQELLREKQQEVKQLQKDcirylerisALEKTVKALEFVHTESQKDLDVTKGNLAQAVEHRKKAQAELSSFKILLDD 2036
Cdd:COG1196    215 YRELKEELKELEAELLLLKLR---------ELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEE 285

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2037 TQSEAARVLADNLKLKKELQSNKESIKSQikqkdEDLLRRLEQAEEKHRKEKKNMQEKLDALHREKAHVEETLAEIQVSL 2116
Cdd:COG1196    286 AQAEEYELLAELARLEQDIARLEERRREL-----EERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAEL 360

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2117 TRKDQEMKELQGSLDSTLAQLAAFTKSMSSLQDDRDRvideakkwerrfgdaIQTKEEEVRLKEENCIALKDQLRQMAIH 2196
Cdd:COG1196    361 AEAEEALLEAEAELAEAEEELEELAEELLEALRAAAE---------------LAAQLEELEEAEEALLERLERLEEELEE 425

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2197 MEELKITVSRLEHDKEIWESKAQTELQHHQKAYDKLQEENKELTSQLEDARQLYHDSKNELTKLESELKSLKDQTTDLNN 2276
Cdd:COG1196    426 LEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEG 505

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2277 SLEKCKE-HENNLEGIIKQQEADIQNCKFSCEQLETDLAASRELTSRLHDEINAKE--QKIISLLSGKEEAIQLAVEELH 2353
Cdd:COG1196    506 FLEGVKAaLLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAaiEYLKAAKAGRATFLPLDKIRAR 585

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2354 QQHSKEIKELENLLSQEEEENVALEEENKRALEKTNQLTEALEAIKKES-FEQKAQLDSFVKSMSSLQDDRDRIVSDYRQ 2432
Cdd:COG1196    586 AALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAaLRRAVTLAGRLREVTLEGEGGSAGGSLTGG 665

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2433 LEERHLSAILEKDQLIQDAAAENNKLKEEMRGLRSHMDDLNSENAKLDAELVQYRRDLNEVIAIKDSQQKQLLDAQLQQN 2512
Cdd:COG1196    666 SRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEE 745

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*
gi 1039751022 2513 KELRNEctkleerlkglEAEKQSLQMSSDALQKEKQGLSKEIKNL 2557
Cdd:COG1196    746 ELLEEE-----------ALEELPEPPDLEELERELERLEREIEAL 779
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 13-888 2.79e-12

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 73.17  E-value: 2.79e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022   13 EDALHRLAEAEKLVVELKDIISQKDVQLqqkdEALQEEKKAAE------NKIKKIKLH-AKAKIMSLNKHMEEIKTQgga 85
Cdd:TIGR02168  175 KETERKLERTRENLDRLEDILNELERQL----KSLERQAEKAErykelkAELRELELAlLVLRLEELREELEELQEE--- 247

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022   86 alpPEAQAEELSKHNKSSTEEEMEIEKIKHELQEKEKLISSLQAQLDQSeqasqldksSAEMEDFVLMKQQLQEKEELIS 165
Cdd:TIGR02168  248 ---LKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYAL---------ANEISRLEQQKQILRERLANLE 315

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  166 TLQTQLSQTQAEQAAQLSSMQQVVREKDARFETQVRLHEDELLQLvtqsdveTEMQQKLRVMQRKLEEHEEALLGRAQVV 245
Cdd:TIGR02168  316 RQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAEL-------EELEAELEELESRLEELEEQLETLRSKV 388

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  246 DLLQKELTSAEQRNQVLSQQLQLLEAEHNTLKNTMETERQE-SKTLMEKVELEVAERKLSFHNLQEEMHQLQGQLERAGQ 324
Cdd:TIGR02168  389 AQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKlEEAELKELQAELEELEEELEELQEELERLEEALEELRE 468

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  325 AQADLETQYSALQQrhktEMEEKTACILSLQKNEQELQSACAALKE--ENSKLLQEKHDQAAESAQAMRQLEDQLQQKSK 402
Cdd:TIGR02168  469 ELEEAEQALDAAER----ELAQLQARLDSLERLQENLEGFSEGVKAllKNQSGLSGILGVLSELISVDEGYEAAIEAALG 544

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  403 EISQFVNKPNLQKNETASQTSLPdvNNEGDQAVMEETVAS---LQKRVVELENEKGALLLSSGELEELKAENEKLSSRI- 478
Cdd:TIGR02168  545 GRLQAVVVENLNAAKKAIAFLKQ--NELGRVTFLPLDSIKgteIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLl 622

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  479 -------TLLEAQNRAGEADGTVCEVSTAGTTLLNRSDSSPEENGQavlENTFSQKHKELSVLLVEMKEAQEEIAFLKSQ 551
Cdd:TIGR02168  623 ggvlvvdDLDNALELAKKLRPGYRIVTLDGDLVRPGGVITGGSAKT---NSSILERRREIEELEEKIEELEEKIAELEKA 699

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  552 LQGKrpegdyevldRREVQLMESEGPPSVTAGDVLCAPSDESSGPAAEEEQAGMKDRHRASEAgplndagmelsspkldg 631
Cdd:TIGR02168  700 LAEL----------RKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQL----------------- 752

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  632 vdkslavshvcqchQGELERLKTQVLELETSLHTAEETYKRNLSEKVKEISSLTQLSEEVKESAEEARSTLAAVTEERDQ 711
Cdd:TIGR02168  753 --------------SKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEE 818

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  712 llyqvkeldvLAELRARVQELESSLAEAEKQrgldYESQRAQHNLLTEQIHSLSIEAKSKDVKIEALQRELDGVQLQFCE 791
Cdd:TIGR02168  819 ----------AANLRERLESLERRIAATERR----LEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERAS 884

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  792 QGTQMKTLQSQLEAKEREVREGTERLRDISQEMEGLSQALSQKELEIAKMDQLLLEKQK----DVETLQQTIQEKDQQVT 867
Cdd:TIGR02168  885 LEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQErlseEYSLTLEEAEALENKIE 964

                          890       900
                   ....*....|....*....|.
gi 1039751022  868 ELSFSMTEKMVQLNEEKFSLG 888
Cdd:TIGR02168  965 DDEEEARRRLKRLENKIKELG 985
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 2064-2882 4.94e-12

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 72.41  E-value: 4.94e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2064 SQIKQKDEDLLRRLEQAEEKHRKEKKNMQEK---LDALHREKAHVEETLAeiqVSLTRKDQEMKELQGSLDSTLAQLAAF 2140
Cdd:TIGR02169  166 AEFDRKKEKALEELEEVEENIERLDLIIDEKrqqLERLRREREKAERYQA---LLKEKREYEGYELLKEKEALERQKEAI 242

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2141 TKSMSSLQDDRDRVIDEAKKWERRFGDAIQTKEEEVR----LKEENCIALKDQLRQMAIHMEELKITVSRLEHDKEiwes 2216
Cdd:TIGR02169  243 ERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKkikdLGEEEQLRVKEKIGELEAEIASLERSIAEKERELE---- 318

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2217 KAQTELQHHQKAYDKLQEENKELTSQLEDARQlyhdsknELTKLESELKSLKDQTTDLNNSLEkckehennlegiikqqe 2296
Cdd:TIGR02169  319 DAEERLAKLEAEIDKLLAEIEELEREIEEERK-------RRDKLTEEYAELKEELEDLRAELE----------------- 374

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2297 adiqnckfsceQLETDLAASRELTSRLHDEINAKEQKIISLLSGKEEAIqlaveELHQQHSKEIKELENLLsqeeeenva 2376
Cdd:TIGR02169  375 -----------EVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQ-----EELQRLSEELADLNAAI--------- 429

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2377 leeenKRALEKTNQLTEALEAIKKESFEQKAQLDSFVKSMSSLQDDRDRIVSDYRQLEERhlsaILEKDQLIQDAAAENN 2456
Cdd:TIGR02169  430 -----AGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKE----LSKLQRELAEAEAQAR 500

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2457 KLKEEMRGLRSHMDDLNSENA---KLDAELVQYRRD------------LNEVIAIKDSQQKQ----LLDAQLQQNKELRN 2517
Cdd:TIGR02169  501 ASEERVRGGRAVEEVLKASIQgvhGTVAQLGSVGERyataievaagnrLNNVVVEDDAVAKEaielLKRRKAGRATFLPL 580

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2518 ECTKLEERLKGLEAEKQSLQMSSDALQKEKQ---------GLSKEIKNLQT--------QLTALQEE----------GTL 2570
Cdd:TIGR02169  581 NKMRDERRDLSILSEDGVIGFAVDLVEFDPKyepafkyvfGDTLVVEDIEAarrlmgkyRMVTLEGElfeksgamtgGSR 660

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2571 GVYHAQLKAKE--EELQRLNMALSSSQKRTADLEEELVCVQKEATRKVSEIEDqLKKELKHLHHDAGIMRNETETAEERV 2648
Cdd:TIGR02169  661 APRGGILFSRSepAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSD-ASRKIGEIEKEIEQLEQEEEKLKERL 739

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2649 AELARDLVEMEQKLLTVTKENKDLMAQIQAFGRSMSSLQdsrdhatEELGDLKKKYDASlkelaqlkEWQDSSREgdvls 2728
Cdd:TIGR02169  740 EELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLE-------EALNDLEARLSHS--------RIPEIQAE----- 799

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2729 qaafplstsenvlsrLEKLNQQLTSKDEQLLHLSSELESSHNQVQSISKAMTSLQNERDRLWSELEKFRKSEE---GKQR 2805
Cdd:TIGR02169  800 ---------------LSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIEnlnGKKE 864

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1039751022 2806 AAAPSAASSPAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQMSQEMTELRPLKAQLQEsqdqtkALQVMEEELRQ 2882
Cdd:TIGR02169  865 ELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKA------KLEALEEELSE 935
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1785-2314 5.13e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 72.28  E-value: 5.13e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1785 IKNYLQQLDQLKGRIAELEMEKQKDRELSQALENEKNALLTQISAKDSELKLLEEEVTKRTTLNQQIQEELCRVTKLKET 1864
Cdd:COG1196    234 LRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRE 313

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1865 AEEEKDDLEErlmnQLAELNGSIGNYYQDVTDAQIKNEQLESEMRNLQRCVSELEEEKQQLVKEKTKVESEIRKEYMEKI 1944
Cdd:COG1196    314 LEERLEELEE----ELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELL 389

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1945 qgaqkgpankshakELQELLREKQQEVKQLQKDCIRYLERISALEKTVKALEFVHTESQKDLDVTKGNLAQAVEHRKKAQ 2024
Cdd:COG1196    390 --------------EALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELE 455

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2025 AELSSFKILLDDTQSEAARVLADNLKLKKELQSNKESIKSQIKQKDEDLLrRLEQAEEKHRKEKKNMQEKLDALHREKAH 2104
Cdd:COG1196    456 EEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEG-FLEGVKAALLLAGLRGLAGAVAVLIGVEA 534

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2105 VEETLAE------IQVSLTRKDQEMKELQGSLDSTLAQLAAF-------------TKSMSSLQDDRDRVIDEAKKWERRF 2165
Cdd:COG1196    535 AYEAALEaalaaaLQNIVVEDDEVAAAAIEYLKAAKAGRATFlpldkiraraalaAALARGAIGAAVDLVASDLREADAR 614

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2166 GDAIQTKEEEVRLKEENCIA-------LKDQLRQMAIHMEELKITVSRLEHDKEIWESKAQTELQHHQKAYDKLQEENKE 2238
Cdd:COG1196    615 YYVLGDTLLGRTLVAARLEAalrravtLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELE 694

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1039751022 2239 LTSQLEDARQLYHDSKNELTKLESELKSLKDQTTDLNNSLEKCKEHENNLEGIIKQQEADIQNCKFSCEQLETDLA 2314
Cdd:COG1196    695 LEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELE 770
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2018-2586 7.45e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 71.51  E-value: 7.45e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2018 EHRKKAQAELSSFKI-LLDDTQSEAARVLADNLKLKKELQSNKESIKSQIKQKDEDLLRrLEQAEEKHRKEKKNMQEKLD 2096
Cdd:COG1196    220 EELKELEAELLLLKLrELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEE-LELELEEAQAEEYELLAELA 298

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2097 ALHREKAHVEETLAEIQVSLTRKDQEMKELQGSLDSTLAQLAAFTKSMSSLQDDRDRVIDEAKKWERRFGDAIQTKEEEV 2176
Cdd:COG1196    299 RLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAE 378

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2177 RLKEENCIALKDQLRQMAIHMEELKITVSRLEhdkeiwesKAQTELQHHQKAYDKLQEENKELTSQLEDARQLYHDSKNE 2256
Cdd:COG1196    379 EELEELAEELLEALRAAAELAAQLEELEEAEE--------ALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEE 450

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2257 LTKLESELKSLKDQTTDLNNSLEKCKEHENNLEGIIKQQEAdiqnckfsceQLETDLAASRELTSRLHDEINAKEQKIIS 2336
Cdd:COG1196    451 EAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAA----------RLLLLLEAEADYEGFLEGVKAALLLAGLR 520

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2337 LLSGKEEAIQLAVEELhqqhSKEIKELENLLSQEEEENVALEEENKRALEKTNQLTEA----LEAIKKESFEQKAQLDSF 2412
Cdd:COG1196    521 GLAGAVAVLIGVEAAY----EAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRAtflpLDKIRARAALAAALARGA 596

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2413 VKSMSSLQDDRDRIVSDYRQLEERHLSAILEKDQLIQDAAAENNKLKEEMRGLRSHMDDLNSENAKLDAELVQYRRDLNE 2492
Cdd:COG1196    597 IGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLE 676

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2493 VIAIKDSQQKQLLDAQLQQNKELRNEctkLEERLKGLEAEKQSLQMSSDALQKEKQGLSKEIKNLQTQLTALQEEGTLGV 2572
Cdd:COG1196    677 AEAELEELAERLAEEELELEEALLAE---EEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEAL 753

                          570
                   ....*....|....
gi 1039751022 2573 YHAQLKAKEEELQR 2586
Cdd:COG1196    754 EELPEPPDLEELER 767
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1561-2343 7.59e-12

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 71.64  E-value: 7.59e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1561 ELQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQELyaklrSTESDKREREKQLQDaeqemeeMKEKMRKFAKSKQQKI 1640
Cdd:TIGR02169  167 EFDRKKEKALEELEEVEENIERLDLIIDEKRQQLERL-----RREREKAERYQALLK-------EKREYEGYELLKEKEA 234

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1641 LEleeendrlraeaqpvggtgESMEALLSSNSSLKEELEKITLEHKTLSKEFEALMAEKDAL--------SEETRNLKLQ 1712
Cdd:TIGR02169  235 LE-------------------RQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELnkkikdlgEEEQLRVKEK 295

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1713 VEAQVLKQASLEAT--EKSDEPKDVIEEVTQAVVGKSQERDALSDSAKLEDSEAILmgdgaKPGVSETFSSHDDIKNYL- 1789
Cdd:TIGR02169  296 IGELEAEIASLERSiaEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKR-----RDKLTEEYAELKEELEDLr 370

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1790 QQLDQLKGRIAELEMEKQKDRELSQALENEKNALLTQISAKDSELKLLEEEVTKrttLNQQIQEELCRVTKLKETAEEEK 1869
Cdd:TIGR02169  371 AELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELAD---LNAAIAGIEAKINELEEEKEDKA 447

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1870 DDLEErLMNQLAELNGSIGNYYQDVTDAQIKNEQLESEMRNLQRCVSELEEEKQQLVKEKT--KVESEIRKEYMEKIQG- 1946
Cdd:TIGR02169  448 LEIKK-QEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRggRAVEEVLKASIQGVHGt 526

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1947 -AQKGPANKSHAKELQELLREKQQEV----KQLQKDCIRYLERISALEKTVKAL-EFVHTESQKDLDVTKGNLAQAVEHR 2020
Cdd:TIGR02169  527 vAQLGSVGERYATAIEVAAGNRLNNVvvedDAVAKEAIELLKRRKAGRATFLPLnKMRDERRDLSILSEDGVIGFAVDLV 606

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2021 KKAQAELSSFKILLDDT----QSEAARVLADNLK---LKKEL---------QSNKESIKSQIKQKDEDLLRRLEQAEEKH 2084
Cdd:TIGR02169  607 EFDPKYEPAFKYVFGDTlvveDIEAARRLMGKYRmvtLEGELfeksgamtgGSRAPRGGILFSRSEPAELQRLRERLEGL 686

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2085 RKEKKNMQEKLDALHREKAHVEETLAEIQVSLTRKDQEMKELQGSLDSTLAQLAAFTKSMSSLQDDRDRVIDEAKKWERR 2164
Cdd:TIGR02169  687 KRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEAR 766

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2165 FGDaIQTKEEEVRLKEENCIA--LKDQLRQMAIHMEELKITVSRLE---HDKEIWESKAQTELQHHQKAYDKLQEENKEL 2239
Cdd:TIGR02169  767 IEE-LEEDLHKLEEALNDLEArlSHSRIPEIQAELSKLEEEVSRIEarlREIEQKLNRLTLEKEYLEKEIQELQEQRIDL 845

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2240 TSQLEDARQLYHDSKNELTKLESELKSLKDQTTDLNNSLEKCKEHENNLEGIIKQQEADIQNCKFSCEQLETDLAASREL 2319
Cdd:TIGR02169  846 KEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAK 925

                          810       820
                   ....*....|....*....|....
gi 1039751022 2320 TSRLHDEINAKEQKIISLLSGKEE 2343
Cdd:TIGR02169  926 LEALEEELSEIEDPKGEDEEIPEE 949
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1382-1975 9.20e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 71.51  E-value: 9.20e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1382 EQERLIKALHTQLEMQAKEHEERLKQAQVEicelkkkptELEEETNAKQQLQRKLQAALISRKEALKEnksLQEQLSSAR 1461
Cdd:COG1196    220 EELKELEAELLLLKLRELEAELEELEAELE---------ELEAELEELEAELAELEAELEELRLELEE---LELELEEAQ 287

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1462 DAVERLTKSLADVESQVSVQNQEKDAvlgkltiLQEERDKLIAEMDRfllenqslsgsceslklalggLTEDKEKLMEEL 1541
Cdd:COG1196    288 AEEYELLAELARLEQDIARLEERRRE-------LEERLEELEEELAE---------------------LEEELEELEEEL 339

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1542 EsvrsskmaestEWQEKHKELQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQELYAKLRSTESDKREREKQLQDAEQE 1621
Cdd:COG1196    340 E-----------ELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEA 408

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1622 MEEMKEKMRKFAKSKQQKILELEEENDRLRAEAQPVggtgESMEALLSSNSSLKEELEKITLEHKTLSKEFEALMAEKDA 1701
Cdd:COG1196    409 EEALLERLERLEEELEELEEALAELEEEEEEEEEAL----EEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLE 484

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1702 LSEETRNLKLQVEAQVLKQASLEATEKSDEPKDVIEEVTQAVvgksqeRDALSDSAKLEDSEAILMGDGAKPGVSETFSS 1781
Cdd:COG1196    485 ELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAV------AVLIGVEAAYEAALEAALAAALQNIVVEDDEV 558

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1782 HDDIKNYLQQldQLKGRIAELEMEKQKDRELSQALEnEKNALLTQISAKDSELKLLEEevtkRTTLNQQIQEELCRVTKL 1861
Cdd:COG1196    559 AAAAIEYLKA--AKAGRATFLPLDKIRARAALAAAL-ARGAIGAAVDLVASDLREADA----RYYVLGDTLLGRTLVAAR 631

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1862 KETAEEEKDDLEERLmnQLAELNGSIGNYYQDVTDAQIKNEQLESEMRNLQRCVSELEEEKQQLVKEKTKVESEIRKEYM 1941
Cdd:COG1196    632 LEAALRRAVTLAGRL--REVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEEREL 709

                          570       580       590
                   ....*....|....*....|....*....|....
gi 1039751022 1942 EKIQGAQKGPANKSHAKELQELLREKQQEVKQLQ 1975
Cdd:COG1196    710 AEAEEERLEEELEEEALEEQLEAEREELLEELLE 743
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1532-2405 1.81e-11

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 70.48  E-value: 1.81e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1532 EDKEKLMEELESVRSSKMAESTEWQEKHKELQKeyevllqsYENVSNEAERIQHVVESVRQ-EKQELYAKLRSTESDKRE 1610
Cdd:TIGR02169  170 RKKEKALEELEEVEENIERLDLIIDEKRQQLER--------LRREREKAERYQALLKEKREyEGYELLKEKEALERQKEA 241

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1611 REKQLQDAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEaqpvgGTGESMEallssnssLKEELEKITLEHKTLSK 1690
Cdd:TIGR02169  242 IERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDL-----GEEEQLR--------VKEKIGELEAEIASLER 308

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1691 EFEALMAEKDALSEETRNLKLQVEAQVLKQASLEatEKSDEPKDVIEEVTQAVVGKSQERDALSDSAKLEDSEAilmgdg 1770
Cdd:TIGR02169  309 SIAEKERELEDAEERLAKLEAEIDKLLAEIEELE--REIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEF------ 380

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1771 akpgvSETFSSHDDIKnylQQLDQLKGRIAELEMEKQKDRELSQALENEKNALLTQISAKDSELKLLEEEVTKRTTLNQQ 1850
Cdd:TIGR02169  381 -----AETRDELKDYR---EKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKK 452

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1851 IQEELCRVTKLKETAEEEKDDLEERLmnqlaelngsignyyqdvtdaqiknEQLESEMRNLQRCVSELEEEKQQLVKEKT 1930
Cdd:TIGR02169  453 QEWKLEQLAADLSKYEQELYDLKEEY-------------------------DRVEKELSKLQRELAEAEAQARASEERVR 507

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1931 --KVESEIRKEYMEKIQG--AQKGPANKSHAKELQELLREKQQEV----KQLQKDCIRYLERISALEKTVKAL-EFVHTE 2001
Cdd:TIGR02169  508 ggRAVEEVLKASIQGVHGtvAQLGSVGERYATAIEVAAGNRLNNVvvedDAVAKEAIELLKRRKAGRATFLPLnKMRDER 587

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2002 SQKDLDVTKGNLAQAVEHRKKAQAELSSFKILLDDT----QSEAARVLADNLK---LKKEL---------QSNKESIKSQ 2065
Cdd:TIGR02169  588 RDLSILSEDGVIGFAVDLVEFDPKYEPAFKYVFGDTlvveDIEAARRLMGKYRmvtLEGELfeksgamtgGSRAPRGGIL 667

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2066 IKQKDEDLLRRLEQAEEKHRKEKKNMQEKLDALHREKAHVEETLAEIQVSLTRKDQEMKELQGSLDSTLAQLAAFTKSMS 2145
Cdd:TIGR02169  668 FSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLS 747

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2146 SLQDDRDRVIDEAKKWERRFGDaIQTKEEEVRLKEENCIA--LKDQLRQMAIHMEELKITVSRLE---HDKEIWESKAQT 2220
Cdd:TIGR02169  748 SLEQEIENVKSELKELEARIEE-LEEDLHKLEEALNDLEArlSHSRIPEIQAELSKLEEEVSRIEarlREIEQKLNRLTL 826

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2221 ELQHHQKAYDKLQEENKELTSQLEDARQLYHDSKNELTKLESELKSLKDQTTDLNNSLEKCKEHENNLEGIIKQQEADIQ 2300
Cdd:TIGR02169  827 EKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIE 906

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2301 NCKFSCEQLETDLAASRELTSRLHDEINAKEQKIISLLSGKEEA-----IQLAVEELHQQHSK----------EIKELEN 2365
Cdd:TIGR02169  907 ELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEElsledVQAELQRVEEEIRAlepvnmlaiqEYEEVLK 986

                          890       900       910       920
                   ....*....|....*....|....*....|....*....|
gi 1039751022 2366 LLSQEEEENVALEEENKRALEKTNQLTEALEAIKKESFEQ 2405
Cdd:TIGR02169  987 RLDELKEKRAKLEEERKAILERIEEYEKKKREVFMEAFEA 1026
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2217-3018 4.08e-11

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 69.32  E-value: 4.08e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2217 KAQTELQHHQKAYDKLQEENKELTSQLE------DARQLYHDSKNELTKLESELksLKDQTTDLNNSLEKCKEHENNLEG 2290
Cdd:TIGR02168  176 ETERKLERTRENLDRLEDILNELERQLKslerqaEKAERYKELKAELRELELAL--LVLRLEELREELEELQEELKEAEE 253

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2291 IIKQQEADIQNCKfscEQLETDLAASRELTSRLhDEINAKEQKIISLLSGKEEAIQLAVEELHQQHsKEIKELENLLSQE 2370
Cdd:TIGR02168  254 ELEELTAELQELE---EKLEELRLEVSELEEEI-EELQKELYALANEISRLEQQKQILRERLANLE-RQLEELEAQLEEL 328

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2371 EEENVALEEENKRALEKTNQLTEALEAIKKESFEQKAQLDSFVKSMSSLQDDRDRIVSDYRQLEERHLSA---ILEKDQL 2447
Cdd:TIGR02168  329 ESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLnneIERLEAR 408

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2448 IQDAAAENNKLKEEMRGLRSHMDDlnsenakldAELVQYRRDLNEVIAIKDSQQKQLLDAQlQQNKELRNECTKLEERLK 2527
Cdd:TIGR02168  409 LERLEDRRERLQQEIEELLKKLEE---------AELKELQAELEELEEELEELQEELERLE-EALEELREELEEAEQALD 478

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2528 GLEAEKQSLQMSSDALQK---EKQGLSKEIKNLQtqLTALQEEGTLGVYHAQLKAKEEELQRLNMALSSS--QKRTADLE 2602
Cdd:TIGR02168  479 AAERELAQLQARLDSLERlqeNLEGFSEGVKALL--KNQSGLSGILGVLSELISVDEGYEAAIEAALGGRlqAVVVENLN 556

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2603 EELVCVQ---KEATRKVS----------EIEDQLKKELKHLHHDAGIMRNETETAE----------------ERVAELAR 2653
Cdd:TIGR02168  557 AAKKAIAflkQNELGRVTflpldsikgtEIQGNDREILKNIEGFLGVAKDLVKFDPklrkalsyllggvlvvDDLDNALE 636

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2654 DLVEMEQKLLTVTKENKDLMAQ-IQAFGR-----SMSSLQDSRDHATEELGDLKKKYDASLKELAQLKEWQDSSREgdVL 2727
Cdd:TIGR02168  637 LAKKLRPGYRIVTLDGDLVRPGgVITGGSaktnsSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEE--EL 714

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2728 SQAAFPLSTSENVLSRLEKLNQQLTSKDEQLLHLSSELESSHNQVQSISKAMTSLQNERDRLWSELEKFRKSEEGKQRAA 2807
Cdd:TIGR02168  715 EQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQL 794

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2808 APSAASSPAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQMSQEMTELRPLKAQLQESQDQTkALQVMEEELRQENLSW 2887
Cdd:TIGR02168  795 KEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESL-AAEIEELEELIEELES 873

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2888 QHELRQLRMEKNSWELHERRMKEQFLMA-ISDKDQQLGHLQSLLRELRSS--------SQAQILSTQYQRQASPETSASL 2958
Cdd:TIGR02168  874 ELEALLNERASLEEALALLRSELEELSEeLRELESKRSELRRELEELREKlaqlelrlEGLEVRIDNLQERLSEEYSLTL 953

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1039751022 2959 DGSQKLVYETELLRTQLNDSLKEIHQKELRIQQLN----SKFSQLLEEKNVLSTQLSDASQSLR 3018
Cdd:TIGR02168  954 EEAEALENKIEDDEEEARRRLKRLENKIKELGPVNlaaiEEYEELKERYDFLTAQKEDLTEAKE 1017
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 223-1046 5.15e-11

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 68.94  E-value: 5.15e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  223 KLRVMQRKLEEHEEALLGRAQVVDLLQKELTSAEQRNQVLSQQLQLLEAEHNTLKNTMETERQESKTLMEKVELEVAERK 302
Cdd:TIGR02169  178 ELEEVEENIERLDLIIDEKRQQLERLRREREKAERYQALLKEKREYEGYELLKEKEALERQKEAIERQLASLEEELEKLT 257

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  303 LSFHNLQEEMHQLQGQLEragQAQADLETQYSALQQRHKTEMEEKTACILSLQKNEQELQSACAALKEENSKLLQEKHDQ 382
Cdd:TIGR02169  258 EEISELEKRLEEIEQLLE---ELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKL 334

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  383 AAESAQAMRQLEDQLQQKSKEISQFVNkpnLQKNETASQTSLPDVNNEGDQAVMEetVASLQKRVVELENEKGALLlssG 462
Cdd:TIGR02169  335 LAEIEELEREIEEERKRRDKLTEEYAE---LKEELEDLRAELEEVDKEFAETRDE--LKDYREKLEKLKREINELK---R 406

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  463 ELEELKAENEKLSSRITLLEAQNRAGEADgtVCEVSTAGTTLLNRSDSSPEENGQAV-----LENTFSQKHKELSVLLVE 537
Cdd:TIGR02169  407 ELDRLQEELQRLSEELADLNAAIAGIEAK--INELEEEKEDKALEIKKQEWKLEQLAadlskYEQELYDLKEEYDRVEKE 484

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  538 MKEAQEEIAFLKSQLQGKRPEgdyeVLDRREVQLMESEGPPSV--------------------TAGDVLCAPSDESSGPA 597
Cdd:TIGR02169  485 LSKLQRELAEAEAQARASEER----VRGGRAVEEVLKASIQGVhgtvaqlgsvgeryataievAAGNRLNNVVVEDDAVA 560

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  598 AEEEQagMKDRHRASEAG--PLN---DAGMELSSPKLDGVDKSL------------AVSHVCQ--------------CHQ 646
Cdd:TIGR02169  561 KEAIE--LLKRRKAGRATflPLNkmrDERRDLSILSEDGVIGFAvdlvefdpkyepAFKYVFGdtlvvedieaarrlMGK 638

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  647 GELERLKTQVLELETSLHTAEETYKRNLSEKVKEISSLTQLSEEvKESAEEARSTLAAVTEERDQLLYqvkeldvlaELR 726
Cdd:TIGR02169  639 YRMVTLEGELFEKSGAMTGGSRAPRGGILFSRSEPAELQRLRER-LEGLKRELSSLQSELRRIENRLD---------ELS 708

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  727 ARVQELESSLAEAEKQRgldyESQRAQHNLLTEQIHSLSIEAKSKDVKIEALQRELDGVQLQFCEQGTQMKTLQSQLEAK 806
Cdd:TIGR02169  709 QELSDASRKIGEIEKEI----EQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDL 784

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  807 ERevREGTERLRDISQEMEGLSQALSQKELEIAKMDQLLLEKQKDVETLQQTIQEKDQQVTELSF---SMTEKMVQLNEE 883
Cdd:TIGR02169  785 EA--RLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEqikSIEKEIENLNGK 862

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  884 KFSLGVEIKTLKEQLNLLSRTEEATKEQVEESGAgsslKLGHDESGQEGLQQELELLRKESEQRKRKLQAalinrkeLLQ 963
Cdd:TIGR02169  863 KEELEEELEELEAALRDLESRLGDLKKERDELEA----QLRELERKIEELEAQIEKKRKRLSELKAKLEA-------LEE 931

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  964 KVSQLEEELAKVREDSRKEIPFG--ENERRKLEEDRENRDDPEEWGTSKWREVEASLKQtISEKEVELEGIRRDLKEKTA 1041
Cdd:TIGR02169  932 ELSEIEDPKGEDEEIPEEELSLEdvQAELQRVEEEIRALEPVNMLAIQEYEEVLKRLDE-LKEKRAKLEEERKAILERIE 1010


                   ....*
gi 1039751022 1042 AEEEL 1046
Cdd:TIGR02169 1011 EYEKK 1015
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1319-2112 1.15e-10

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 67.79  E-value: 1.15e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1319 ELLKQELESSQLKVAGLE-HLKTLQPELDALHKHMGQKEEEVNYLYGQLSEK-EQTLTTVQTEMVE---QERLIKALHTQ 1393
Cdd:TIGR02169  233 EALERQKEAIERQLASLEeELEKLTEEISELEKRLEEIEQLLEELNKKIKDLgEEEQLRVKEKIGEleaEIASLERSIAE 312

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1394 LEMQAKEHEERLKQAQVEICELKKKPTELEEETNAKQQLQRKLQAALISRKEalKENKSLQEqlssardaverltksLAD 1473
Cdd:TIGR02169  313 KERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKE--ELEDLRAE---------------LEE 375

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1474 VESQVSVQNQEKDAVLGKLTILQEERDKLIAEMDRFLLENQSLSGSCESLKLALGGLTEDKEKLMEELESVRsskmAEST 1553
Cdd:TIGR02169  376 VDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKA----LEIK 451

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1554 EWQEKHKELQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQELYAKLRSTESDKREREKQLQDAEQEMEEMKEKMRKFA 1633
Cdd:TIGR02169  452 KQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLG 531

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1634 KSKQQKILELE-EENDRLRAEAQPVGGTGESMEALLSSNSSLKEE---LEKITLEHKTLSKefealMAEKDALS------ 1703
Cdd:TIGR02169  532 SVGERYATAIEvAAGNRLNNVVVEDDAVAKEAIELLKRRKAGRATflpLNKMRDERRDLSI-----LSEDGVIGfavdlv 606

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1704 ---EETRNLKLQVEAQVLKQASLEATEKSDE-------PKDVIEEVTQAVVGKSQERDALSDSAKLEDSEailmgdgakP 1773
Cdd:TIGR02169  607 efdPKYEPAFKYVFGDTLVVEDIEAARRLMGkyrmvtlEGELFEKSGAMTGGSRAPRGGILFSRSEPAEL---------Q 677

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1774 GVSETFSSHDDIKNYLQQ-LDQLKGRIAELEMEKQKDRELSQALENEKNALLTQISAKDSELKLLEEEVtkrttlnQQIQ 1852
Cdd:TIGR02169  678 RLRERLEGLKRELSSLQSeLRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDL-------SSLE 750

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1853 EELCRVTKLKETAEEEKDDLEERLMNQLAELNgsignyyqdvtdaQIKNEQLESEMRNLQRCVSELEEEKQQLVKEKTKV 1932
Cdd:TIGR02169  751 QEIENVKSELKELEARIEELEEDLHKLEEALN-------------DLEARLSHSRIPEIQAELSKLEEEVSRIEARLREI 817

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1933 ESEIRKEYMEKIQGAQKGPANKSHAKELQELLREKQQEVKQLQKDCIRYLERISALEKTVKALEFVHTESQKDLDVTKGN 2012
Cdd:TIGR02169  818 EQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQ 897

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2013 LAQAVEHRKKAQAELSSFKILLDDTQsEAARVLADNLK----LKKELQSNKESIKS--QIKQKDEDLLRRLEQAE----- 2081
Cdd:TIGR02169  898 LRELERKIEELEAQIEKKRKRLSELK-AKLEALEEELSeiedPKGEDEEIPEEELSleDVQAELQRVEEEIRALEpvnml 976

                          810       820       830
                   ....*....|....*....|....*....|....*.
gi 1039751022 2082 -----EKHRKEKKNMQEKLDALHREKAHVEETLAEI 2112
Cdd:TIGR02169  977 aiqeyEEVLKRLDELKEKRAKLEEERKAILERIEEY 1012
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2170-2714 2.10e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 66.88  E-value: 2.10e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2170 QTKEEEVRLKEENCIALKDQLRQMAIhmEELKITVSRLEHDKEiwesKAQTELQHHQKAYDKLQEENKELTSQLEDARQL 2249
Cdd:COG1196    216 RELKEELKELEAELLLLKLRELEAEL--EELEAELEELEAELE----ELEAELAELEAELEELRLELEELELELEEAQAE 289

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2250 YHDSKNELTKLESELKSLKDQTTDLNNSLEKCKEHENNLEGIIKQQEADIQNCKFSCEQLETDLAASRELTSRLHDEINA 2329
Cdd:COG1196    290 EYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLE 369

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2330 KEQKIISLLSGKEEAIQLAVEELHQQ--HSKEIKELENLLSQEEEENVALEEENKRALEKTNQLTEALEAIKKESFEQKA 2407
Cdd:COG1196    370 AEAELAEAEEELEELAEELLEALRAAaeLAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAE 449

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2408 QLDSFVKSMSSLQDDRDRIVSDYRQLEERHLSAILEKDQLIQDAAAENN---------------KLKEEMRGLRSHMDDL 2472
Cdd:COG1196    450 EEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEaeadyegflegvkaaLLLAGLRGLAGAVAVL 529

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2473 NSENAKLDAELVQYRRDLNEVIAIKDSQQKQLLDAQLQQNKELRNECTKLEERLKGLEAEKQSLQMSSDALQKEKQGLSK 2552
Cdd:COG1196    530 IGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLR 609

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2553 EIKNLQTQLTALQEEGTL--------GVYHAQLKAKEEELQRLNMALSSSQKRTADLEEELVCVQKEATRKVSEIEDQLK 2624
Cdd:COG1196    610 EADARYYVLGDTLLGRTLvaarleaaLRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLA 689

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2625 KELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLTVTKENKDLMAQIQAFGRSMSSLQDSRDHATEELGDLKKKY 2704
Cdd:COG1196    690 EEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELEREL 769

                          570
                   ....*....|
gi 1039751022 2705 DASLKELAQL 2714
Cdd:COG1196    770 ERLEREIEAL 779
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 696-1051 2.71e-10

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 66.63  E-value: 2.71e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  696 EEARSTLAAVTEERDQLLYQVKELD-VLAELRARVQELESSLAEAEKQRGLDYESQRAQHNLLTEQIHSLSIEAKSKDVK 774
Cdd:TIGR02169  166 AEFDRKKEKALEELEEVEENIERLDlIIDEKRQQLERLRREREKAERYQALLKEKREYEGYELLKEKEALERQKEAIERQ 245

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  775 IEALQRELDGVQLQFCEQGTQMKTLQSQLEAKEREVRE-GTERLRDISQEMEGLSQALSQKELEIAKMDQLLLEKQKDVE 853
Cdd:TIGR02169  246 LASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDlGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLA 325

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  854 TLQQTIQEKDQQVTELSfsmtEKMVQLNEEKFSLGVEIKTLKEQLNLLsrteEATKEQVEESGAGSSLKLGHDESGQEGL 933
Cdd:TIGR02169  326 KLEAEIDKLLAEIEELE----REIEEERKRRDKLTEEYAELKEELEDL----RAELEEVDKEFAETRDELKDYREKLEKL 397

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  934 QQELELLRKESEQRKRKLQAALINRKELLQKVSQLEE---ELAKVREDSRKEIPFGENERRKLEEDRENRDDPEEWGTSK 1010
Cdd:TIGR02169  398 KREINELKRELDRLQEELQRLSEELADLNAAIAGIEAkinELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEE 477

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....
gi 1039751022 1011 WREVE---ASLKQTISEKEVELEGIRRDLKEKTAAEEELQAVVQ 1051
Cdd:TIGR02169  478 YDRVEkelSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQ 521
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2381-3122 6.99e-10

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 65.46  E-value: 6.99e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2381 NKRALEKTNQLTEALEAIKKEsfEQKAQLDSFVKSMSSLQDDRDR---IVSDYRQLEERHLSAILEKDQLIQDAAAENNK 2457
Cdd:TIGR02168  201 QLKSLERQAEKAERYKELKAE--LRELELALLVLRLEELREELEElqeELKEAEEELEELTAELQELEEKLEELRLEVSE 278

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2458 LKEEMRGLRSHMDDLNSENAKLDAELVQYRRDLNEViaikdSQQKQLLDAQLQQNKELRNEctkLEERLKGLEAEKQSLQ 2537
Cdd:TIGR02168  279 LEEEIEELQKELYALANEISRLEQQKQILRERLANL-----ERQLEELEAQLEELESKLDE---LAEELAELEEKLEELK 350

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2538 MSSDALQKEKQGLSKEIKNLQTQLTALQEEgtlgvyHAQLKAKEEELQRlnmALSSSQKRTADLEEELVCVQKEATRKVS 2617
Cdd:TIGR02168  351 EELESLEAELEELEAELEELESRLEELEEQ------LETLRSKVAQLEL---QIASLNNEIERLEARLERLEDRRERLQQ 421

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2618 EIEDQLKKELKHLHHDAGIMRNETETAEErvaELARDLVEMEQKLLTVTKENKDLMAQIQAFGRSMSSLQdSRDHATEEL 2697
Cdd:TIGR02168  422 EIEELLKKLEEAELKELQAELEELEEELE---ELQEELERLEEALEELREELEEAEQALDAAERELAQLQ-ARLDSLERL 497

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2698 GDLKKKYDASLKELAQLKEWqdssregdvLSQAAFPLSTSENVLSRLEKLNQQLTSKDEQLLhLSSELESSHNQVQSISK 2777
Cdd:TIGR02168  498 QENLEGFSEGVKALLKNQSG---------LSGILGVLSELISVDEGYEAAIEAALGGRLQAV-VVENLNAAKKAIAFLKQ 567

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2778 AmtslqNERDRLWSELEKFRKSE-EGKQRAAAPSAASSPAEVQSLKKAMSSLQNDRDRLL------KELKNLQQQYLQMS 2850
Cdd:TIGR02168  568 N-----ELGRVTFLPLDSIKGTEiQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLggvlvvDDLDNALELAKKLR 642

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2851 QEMT-------------------------------ELRPLKAQLQESQDQTKALQVMEEELRQENLSWQHELRQLRMEKN 2899
Cdd:TIGR02168  643 PGYRivtldgdlvrpggvitggsaktnssilerrrEIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELE 722

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2900 SWELHERRMKEQfLMAISDKDQQLGHLQSLLRELRSSSQAQILSTQYQR-QASPETSASLDGSQKLVYETELLRTQLNDS 2978
Cdd:TIGR02168  723 ELSRQISALRKD-LARLEAEVEQLEERIAQLSKELTELEAEIEELEERLeEAEEELAEAEAEIEELEAQIEQLKEELKAL 801

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2979 LKEIHQKELRIQQLNSKFSQLLEEKNVLSTQLSDASQSLRENQHHYSNLFNHCAILEKEVQKLQAGP--LNTDVapgapq 3056
Cdd:TIGR02168  802 REALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIeeLESEL------ 875

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1039751022 3057 EKNGMHRKSEPETTGEEQPSFSEVQQQLCNTKQDLRELKKLLEEERDQRLTAENALSLAKEQIRRL 3122
Cdd:TIGR02168  876 EALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNL 941
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2359-2897 7.83e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 64.96  E-value: 7.83e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2359 EIKELENLLSQEEEENVALEEENKRALEKTNQLTEALEAIKKESFEQKAQLDSFVKSMSSLQDDRDRIVSDYRQLEERHL 2438
Cdd:COG1196    233 KLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRR 312

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2439 SAILEKDQL---IQDAAAENNKLKEEMRGLRSHMDDLNSENAKLDAELVQYRRDLNEVIAIKDSQQKQLLDAQLQQNKEL 2515
Cdd:COG1196    313 ELEERLEELeeeLAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEAL 392

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2516 RNEcTKLEERLKGLEAEKQSLQMSSDALQKEKQGLSKEIKNLQTQLTALQEEgtLGVYHAQLKAKEEELQRLNMALSSSQ 2595
Cdd:COG1196    393 RAA-AELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEA--LEEAAEEEAELEEEEEALLELLAELL 469

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2596 KRTADLEEELVCVQKEATRKVSEIEDQLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLTVTKENKDLMAQ 2675
Cdd:COG1196    470 EEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQ 549

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2676 IQAFGRSMSSLQDSRDHATEELGDLKKKYDASLKELAQLKEWQDSSREGDVLSQAAFPLSTSENVLSRLEKLNQQLTSKD 2755
Cdd:COG1196    550 NIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVA 629

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2756 EQLLHLSSELESSHNQVQSISKAMTSLQNERDRLwselekfRKSEEGKQRAAAPSAASSPAEVQSLKKAMSSLQNDRDRL 2835
Cdd:COG1196    630 ARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLT-------GGSRRELLAALLEAEAELEELAERLAEEELELEEALLAE 702

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1039751022 2836 LKELKNLQQQYLQMSQEMTELRPLKAQLQESQDQTKALQVMEEELRQENL-----------SWQHELRQLRME 2897
Cdd:COG1196    703 EEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEAleelpeppdleELERELERLERE 775
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 115-760 1.00e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 64.57  E-value: 1.00e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  115 HELQEKEKLISSLQAQLDQSEQASQLDKSSAEMEDFVLMKQQLQEKEELISTLQTQLSQTQAEQAAQLSSMQQVVREKDA 194
Cdd:COG1196    216 RELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLA 295

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  195 RFET-------QVRLHEDELLQLVTQSDVETEMQQKLRVMQRKLEEHEEALLGRAQVVDLLQKELTSAEQRNQVLSQQLQ 267
Cdd:COG1196    296 ELARleqdiarLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELA 375

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  268 LLEAEHNTLKNTMETERQESKtlmekvelevaerklsfhNLQEEMHQLQGQLERAGQAQADLETQYSALQQRHKTEMEEK 347
Cdd:COG1196    376 EAEEELEELAEELLEALRAAA------------------ELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEE 437

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  348 taciLSLQKNEQELQSACAALKEENSKLLQEKHDQAAESAQAMRQLEDQLQQKSKEISQFVNKPNLQKNETASQTSLPDV 427
Cdd:COG1196    438 ----EEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAA 513

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  428 NNEGDQAVMEETVASLQKRVVELENEKGALLLssGELEELKAENEKLSSRITLLEAQNRAGEAdgTVCEVSTAGTTLLNR 507
Cdd:COG1196    514 LLLAGLRGLAGAVAVLIGVEAAYEAALEAALA--AALQNIVVEDDEVAAAAIEYLKAAKAGRA--TFLPLDKIRARAALA 589

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  508 SDSSPEENGQAVLENTFsqkhkelsvllvemkEAQEEIAFLksqlqgkRPEGDYEVLDRREVQLMESEGPPSVTAGDVLc 587
Cdd:COG1196    590 AALARGAIGAAVDLVAS---------------DLREADARY-------YVLGDTLLGRTLVAARLEAALRRAVTLAGRL- 646

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  588 apsDESSGPAAEEEQAGMKDRHRASEAGPLNDAGMELSSPKLDGVDKslavshvcqcHQGELERLKTQVLELETSLHTAE 667
Cdd:COG1196    647 ---REVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAE----------EELELEEALLAEEEEERELAEAE 713

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  668 ETYKRNLSEKVKEISSLTQLSEEVKESAEEARSTLAAVTEERDQLLYQVKELDV-LAELRARVQELES--SLAEAEkqrg 744
Cdd:COG1196    714 EERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELEReLERLEREIEALGPvnLLAIEE---- 789

                          650
                   ....*....|....*.
gi 1039751022  745 ldYESQRAQHNLLTEQ 760
Cdd:COG1196    790 --YEELEERYDFLSEQ 803
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 645-1198 1.24e-09

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 64.31  E-value: 1.24e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  645 HQGELERLKTQVLELETSLHTAE---ETYKRNLSEKVKEISSLTQLSEEVKESAEEARSTLA----AVTEERDQLLYQVK 717
Cdd:TIGR02168  307 LRERLANLERQLEELEAQLEELEsklDELAEELAELEEKLEELKEELESLEAELEELEAELEelesRLEELEEQLETLRS 386

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  718 ELDVL----AELRARVQELESSLAEAEKQRG-LDYESQRAQHNLLTEQIHSLSIEAKSKDVKIEALQRELDGVQLQFCEQ 792
Cdd:TIGR02168  387 KVAQLelqiASLNNEIERLEARLERLEDRRErLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEEL 466

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  793 GTQMKTLQSQLEAKEREVREGTER---LRDISQEMEGLSQALSQ----------------------KELEIAK------- 840
Cdd:TIGR02168  467 REELEEAEQALDAAERELAQLQARldsLERLQENLEGFSEGVKAllknqsglsgilgvlselisvdEGYEAAIeaalggr 546

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  841 MDQLLLEKQ----KDVETLQQ------------TIQEKDQQVTELSFSMTEKMVQL-------NEEKFSLGVE------- 890
Cdd:TIGR02168  547 LQAVVVENLnaakKAIAFLKQnelgrvtflpldSIKGTEIQGNDREILKNIEGFLGvakdlvkFDPKLRKALSyllggvl 626

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  891 -IKTLKEQLNLLSRTEEATK---EQVEESGAGSSLKLGHDE--SGQEGLQQELELLRKESEQRKRKLQAALINRKELLQK 964
Cdd:TIGR02168  627 vVDDLDNALELAKKLRPGYRivtLDGDLVRPGGVITGGSAKtnSSILERRREIEELEEKIEELEEKIAELEKALAELRKE 706

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  965 VSQLEEELAKVREDSRKEIPFGENERRKLEEDRENRDDPEEWGTSKWREVEaSLKQTISEKEVELEGIRRDLKEKTAAEE 1044
Cdd:TIGR02168  707 LEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELT-ELEAEIEELEERLEEAEEELAEAEAEIE 785

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1045 ELQAVVQRMTRDLQSKTKQIDLLQEEVTENQATIQKLVTGTMDAGNggSAAPVKETAASSPPGAGGEEHWKPELEGRILD 1124
Cdd:TIGR02168  786 ELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLER--RIAATERRLEDLEEQIEELSEDIESLAAEIEE 863

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1125 LEKDKTQLQKKLQEALIARKAI----------LKKAQEKEKQLKEELREQKDAYHHLQGQFHEQNKEKENIADQLRQLQC 1194
Cdd:TIGR02168  864 LEELIEELESELEALLNERASLeealallrseLEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQE 943


                   ....
gi 1039751022 1195 QARE 1198
Cdd:TIGR02168  944 RLSE 947
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1129-1938 1.61e-09

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 63.92  E-value: 1.61e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1129 KTQLQKKLQEALIARKAILKKAQEKEKQL---KEELREQKDAYHHLQGQFHEQNKEKENIADQLRQLQCQaresidrqlp 1205
Cdd:TIGR02168  199 ERQLKSLERQAEKAERYKELKAELRELELallVLRLEELREELEELQEELKEAEEELEELTAELQELEEK---------- 268

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1206 gtgqqepgppapsLEGISLEDTEpaSESDLHAAQpsppgetAALQATVSvaqiqaqlkemevekeelelKVSSIASELAK 1285
Cdd:TIGR02168  269 -------------LEELRLEVSE--LEEEIEELQ-------KELYALAN--------------------EISRLEQQKQI 306

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1286 KSEEVLLLQDQINEQGLEIQNLKAASVEAQAHTELLKQELESSQLKVAGL-EHLKTLQPELDALHKHMGQKEEEVNYLYG 1364
Cdd:TIGR02168  307 LRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLeAELEELEAELEELESRLEELEEQLETLRS 386

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1365 QLSEKEQTLTTVQTEMVEQERLIKALHTQLEMQAKEHEERLKQAQveicelKKKPTELEEETNAKQQLQRKLQAALISRK 1444
Cdd:TIGR02168  387 KVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLE------EAELKELQAELEELEEELEELQEELERLE 460

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1445 EALKENKSLQEQLSSARDAVERLTKSL-ADVESQVSVQNQEKDAVLGKLTILQeERDKLIAEMDRFLLENQSLSGSCESL 1523
Cdd:TIGR02168  461 EALEELREELEEAEQALDAAERELAQLqARLDSLERLQENLEGFSEGVKALLK-NQSGLSGILGVLSELISVDEGYEAAI 539

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1524 KLALGG-----LTEDKEKLMEELESVRSSKMAEST---EWQEKHKELQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQ 1595
Cdd:TIGR02168  540 EAALGGrlqavVVENLNAAKKAIAFLKQNELGRVTflpLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALS 619

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1596 ELYAKLRSTESdkrerekqLQDAEQEmeemkekmrkfAKSKQQKILELEEENDRLRAEAQPVGGTGESMEALLssnsSLK 1675
Cdd:TIGR02168  620 YLLGGVLVVDD--------LDNALEL-----------AKKLRPGYRIVTLDGDLVRPGGVITGGSAKTNSSIL----ERR 676

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1676 EELEKITLEHKTLSKEFEALMAEKDALSEETRNLKLQVEAqvLKQASLEATEKSDEPKDVIEEVTQavvgKSQERDALSD 1755
Cdd:TIGR02168  677 REIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQ--LRKELEELSRQISALRKDLARLEA----EVEQLEERIA 750

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1756 SAKLEDSEAIlmgdgakpgvsetfsshDDIKNYLQQLDQLKGRIAELEMEKQKDRELSQALENEKNALLTQISAKDSELK 1835
Cdd:TIGR02168  751 QLSKELTELE-----------------AEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELT 813

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1836 LLEEEVTKRTTLNQQIQEELCRVTKLKETAEEEKDDLEErlmnQLAELNGSIGNYYQDVTDAQIKNEQLESEMRNLQRCV 1915
Cdd:TIGR02168  814 LLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSE----DIESLAAEIEELEELIEELESELEALLNERASLEEAL 889

                          810       820
                   ....*....|....*....|...
gi 1039751022 1916 SELEEEKQQLVKEKTKVESEIRK 1938
Cdd:TIGR02168  890 ALLRSELEELSEELRELESKRSE 912
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 689-1438 1.76e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 63.93  E-value: 1.76e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  689 EEVKESAEEARSTLAAVTEERDQLLYQVKELDVLAELRARVQELESSL-------AEAEKQRGL-DYESQRAQHNLLTEQ 760
Cdd:TIGR02169  180 EEVEENIERLDLIIDEKRQQLERLRREREKAERYQALLKEKREYEGYEllkekeaLERQKEAIErQLASLEEELEKLTEE 259

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  761 IHSLSIEAKSKDVKIEALQREL----DGVQLQFCEQGTQMKTLQSQLEAK-----------EREVREGTERLRDISQEME 825
Cdd:TIGR02169  260 ISELEKRLEEIEQLLEELNKKIkdlgEEEQLRVKEKIGELEAEIASLERSiaekereledaEERLAKLEAEIDKLLAEIE 339

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  826 GLSQALSQKELEIAKMDQLLLEKQKDVETLQQTIQEKDQQVTELSfsmtEKMVQLNEEKFSLGVEIKTLKEQLNLLsrte 905
Cdd:TIGR02169  340 ELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETR----DELKDYREKLEKLKREINELKRELDRL---- 411

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  906 EATKEQVEESGAGSSLKLGHDESGQEGLQQELELLRKESEQRKRKLQAALINRKELLQKVSQLEEELAKV---REDSRKE 982
Cdd:TIGR02169  412 QEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVekeLSKLQRE 491

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  983 IPFGENERRKLEEDRENRDDPEEWGTSKWREVEASLKQTISEKEvelegiRRDLKEKTAAEEELQAVV------------ 1050
Cdd:TIGR02169  492 LAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGE------RYATAIEVAAGNRLNNVVveddavakeaie 565

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1051 -------QRMT----RDLQSKTKQIDLLQEE----------------------------VTENQATIQKL---------- 1081
Cdd:TIGR02169  566 llkrrkaGRATflplNKMRDERRDLSILSEDgvigfavdlvefdpkyepafkyvfgdtlVVEDIEAARRLmgkyrmvtle 645

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1082 ---------VTGTMDAGNGGSAAPVKETAASsppgaggeehwkPELEGRILDLEKDKTQLQKKLQEALIARKAILKKAQE 1152
Cdd:TIGR02169  646 gelfeksgaMTGGSRAPRGGILFSRSEPAEL------------QRLRERLEGLKRELSSLQSELRRIENRLDELSQELSD 713

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1153 KEKQLKEELREQKDAyhhlqGQFHEQNKEK-ENIADQLRQLQcQARESIDRQLPgtgqqepgppapslegiSLEDTEPAS 1231
Cdd:TIGR02169  714 ASRKIGEIEKEIEQL-----EQEEEKLKERlEELEEDLSSLE-QEIENVKSELK-----------------ELEARIEEL 770

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1232 ESDLHAAQPsppgETAALQATVS---VAQIQAQLKEMEVEKEELELKVSSIASELAKKSEEVLLLQDqineqglEIQNLK 1308
Cdd:TIGR02169  771 EEDLHKLEE----ALNDLEARLShsrIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEK-------EIQELQ 839

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1309 AASVEAQAHTELLKQELESSQLKVAGLE-HLKTLQPELDALHKHMGQKEEEVNYLYGQLSEKEQTLTTVQTEMVEQERLI 1387
Cdd:TIGR02169  840 EQRIDLKEQIKSIEKEIENLNGKKEELEeELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRL 919

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1039751022 1388 KALHTQLEMQakehEERLKQAQVEICELKKKPTELEEETNAKQQLQRKLQA 1438
Cdd:TIGR02169  920 SELKAKLEAL----EEELSEIEDPKGEDEEIPEEELSLEDVQAELQRVEEE 966
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1958-2567 2.65e-09

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 63.12  E-value: 2.65e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1958 KELQELLREKQQEVKQLQKDCIRYLERISALEKTVKALEFVHTESQKDLDVTKGNLAQAVEHRKKAQAELSSFKILLDDT 2037
Cdd:TIGR04523   43 KTIKNELKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDLSKINSEIKNDKEQKNKL 122

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2038 QSEAArvladnlKLKKELQSNKESIKSQIKQ--KDEDLLRRLEQAEEKHRKEKKNMQEKLDALHREKAHVEETLAEIQVS 2115
Cdd:TIGR04523  123 EVELN-------KLEKQKKENKKNIDKFLTEikKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNK 195

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2116 LTR----------KDQEMKELQGSLDSTLAQLAAFTKSMSSLQDDRDRVIDEAKKWERRFGDAIQTKEEEvrlkeencia 2185
Cdd:TIGR04523  196 LLKlelllsnlkkKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKI---------- 265

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2186 lKDQLRQMAIHMEELKITVSRLEhdKEIWESKAQTELQHHQKAydklQEENKELTSQLEdarqlyhDSKNELTKLESELK 2265
Cdd:TIGR04523  266 -KKQLSEKQKELEQNNKKIKELE--KQLNQLKSEISDLNNQKE----QDWNKELKSELK-------NQEKKLEEIQNQIS 331

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2266 SLKDQTTDLNNSLEKCKEHENNLEGIIKQQEADIQNCKFSCEQLETDLAASRELTSRLHDEINAKEQKiISLLSGKEEAI 2345
Cdd:TIGR04523  332 QNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESK-IQNQEKLNQQK 410

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2346 QLAVEELHQQHSKEIKELENLLSQEEEENVALeeenKRALEKTNQLTEALEAIKKESFEQKAQLDSFVKSMSSLQDDRDR 2425
Cdd:TIGR04523  411 DEQIKKLQQEKELLEKEIERLKETIIKNNSEI----KDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQ 486

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2426 IVSDYRQLEERHLSAILEKDQLIQdaaaENNKLKEEMRGLRSHMDDLNSENAKLDAELVQYRRDLNEviaIKDSQQKQLL 2505
Cdd:TIGR04523  487 KQKELKSKEKELKKLNEEKKELEE----KVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNK---DDFELKKENL 559

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1039751022 2506 DAQLQQNKElrnECTKLEERLKGLEAEKQSLQMSSDALQKEKQGLSKEIKNLQTQLTALQEE 2567
Cdd:TIGR04523  560 EKEIDEKNK---EIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKE 618
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1873-2443 3.42e-09

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 62.77  E-value: 3.42e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1873 EERLMNQLAELNGSIGNYYQDVTDAQIKNEQLESEMRNLQRCVSELEEEKQ---QLVKEKTKVESEIRKEyMEKIQGAQK 1949
Cdd:PRK03918   188 TENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEeieELEKELESLEGSKRKL-EEKIRELEE 266

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1950 GPANKshaKELQELLREKQQEVKQLQKDCIRYLERISALEKTVKALefvhtesqKDLDVTKGNLAQAVEHRKKAQAELSS 2029
Cdd:PRK03918   267 RIEEL---KKEIEELEEKVKELKELKEKAEEYIKLSEFYEEYLDEL--------REIEKRLSRLEEEINGIEERIKELEE 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2030 FKILLDDTQseaarvladnlKLKKELQSNKESIKSQIKQKDEdlLRRLEQAEEKHRKEKKN-----MQEKLDALHREKAH 2104
Cdd:PRK03918   336 KEERLEELK-----------KKLKELEKRLEELEERHELYEE--AKAKKEELERLKKRLTGltpekLEKELEELEKAKEE 402

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2105 VEETLAEIQVSLTRKDQEMKELQGSL-------------------DSTLAQLAAFTKSMSSLQDDRDRVIDEAKKWERRF 2165
Cdd:PRK03918   403 IEEEISKITARIGELKKEIKELKKAIeelkkakgkcpvcgrelteEHRKELLEEYTAELKRIEKELKEIEEKERKLRKEL 482

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2166 gdaiqTKEEEVRLKEENCIALKDQLRQMAIHMEELKitvsrlEHDKEIWESKAqTELQHHQKAYDKLQEENKELTSQLED 2245
Cdd:PRK03918   483 -----RELEKVLKKESELIKLKELAEQLKELEEKLK------KYNLEELEKKA-EEYEKLKEKLIKLKGEIKSLKKELEK 550

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2246 ARQLyhdsKNELTKLESELKSLKDQTTDLNNSLEKCK-EHENNLEGIIKQQEA------DIQNCKFSCEQLETDLAASRE 2318
Cdd:PRK03918   551 LEEL----KKKLAELEKKLDELEEELAELLKELEELGfESVEELEERLKELEPfyneylELKDAEKELEREEKELKKLEE 626

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2319 LTSRLHDEINAKEQKIISLLSGKEEAIQLAVEELHQQHSKEIKELENLLSQEEEENVALEEENKRALEKTNQLTEALEAI 2398
Cdd:PRK03918   627 ELDKAFEELAETEKRLEELRKELEELEKKYSEEEYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEER 706

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*
gi 1039751022 2399 KKesfeQKAQLDSFVKSMSSLQDDRDRIVSDYRQLEERHLSAILE 2443
Cdd:PRK03918   707 EK----AKKELEKLEKALERVEELREKVKKYKALLKERALSKVGE 747
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 292-1081 4.82e-09

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 62.38  E-value: 4.82e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  292 EKVELEVAERKLSFHNLQEEMHQLQGQLERAGQAQADLETQYSALQqrhkTEMEEKTACILSLQKNEQELQSACAALKEE 371
Cdd:TIGR02168  221 ELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELE----EKLEELRLEVSELEEEIEELQKELYALANE 296

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  372 NSKLLQEKhdqaAESAQAMRQLEDQLQQKSKEISQFVNKPNLQKNETASqtslpdvnnegdqavMEETVASLQKRVVELE 451
Cdd:TIGR02168  297 ISRLEQQK----QILRERLANLERQLEELEAQLEELESKLDELAEELAE---------------LEEKLEELKEELESLE 357

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  452 NEkgalllssgeLEELKAENEKLSSRITLLEAQNRAgeadgtvcevstagttllNRSDSSPEENGQAVLENTFSQKHKEL 531
Cdd:TIGR02168  358 AE----------LEELEAELEELESRLEELEEQLET------------------LRSKVAQLELQIASLNNEIERLEARL 409

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  532 SVLLVEMKEAQEEIAFLKSQLQGKRPEGDYEVLDRREVQLMESEGppSVTAGDVLCAPSDESSGPAAEEEQAGMKDRHRA 611
Cdd:TIGR02168  410 ERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQE--ELERLEEALEELREELEEAEQALDAAERELAQL 487

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  612 SEAGPLNDAGMELSSPKLDGVDKSLAVSHVCQCHQGELerlkTQVLELETSLHTAEETY---------KRNLSEKVKEIS 682
Cdd:TIGR02168  488 QARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVL----SELISVDEGYEAAIEAAlggrlqavvVENLNAAKKAIA 563

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  683 SLTQ---------------------LSEEVKESAEEARSTLAAVTEERDQL----------LYQVKELDVLAELRARVQE 731
Cdd:TIGR02168  564 FLKQnelgrvtflpldsikgteiqgNDREILKNIEGFLGVAKDLVKFDPKLrkalsyllggVLVVDDLDNALELAKKLRP 643

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  732 LES---------------SLAEAEKQRGLDYESQ-----RAQHNLLTEQIHSLSIEAKSKDVKIEALQRELDGVQLQFCE 791
Cdd:TIGR02168  644 GYRivtldgdlvrpggviTGGSAKTNSSILERRReieelEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEE 723

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  792 QGTQMKTLQSQLEAKEREVREGTERLRDISQEMEGLSQALSQKELEIAKMDQLLLEKQKDVETLQQTIQEKDQQVTELSF 871
Cdd:TIGR02168  724 LSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALRE 803

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  872 SMTEKMVQLNEEKFSLGVEIKTLKEQLNLLSRTE------EATKEQVEESGAGSSLKLGHDESGQEGLQQELELLRKESE 945
Cdd:TIGR02168  804 ALDELRAELTLLNEEAANLRERLESLERRIAATErrledlEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERA 883

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  946 QRKRKLQAALINRKELLQKVSQLEEELAKVREDSRKEIPFGENERRKLEEDRENRDDPEEWGTSKWREVEASLKQTISEK 1025
Cdd:TIGR02168  884 SLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKI 963

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1039751022 1026 EVELEGIRRDLKEKT-----------AAEEELQAVVQRmtrdLQSKTKQIDLLQEEVTENQATIQKL 1081
Cdd:TIGR02168  964 EDDEEEARRRLKRLEnkikelgpvnlAAIEEYEELKER----YDFLTAQKEDLTEAKETLEEAIEEI 1026
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2237-2842 6.52e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 61.88  E-value: 6.52e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2237 KELTSQLEDARQlYHDSKNELTKLESELKSLKDQttdlnnslekckehenNLEGIIKQQEADIQNCKFSCEQLETDLAAS 2316
Cdd:COG1196    203 EPLERQAEKAER-YRELKEELKELEAELLLLKLR----------------ELEAELEELEAELEELEAELEELEAELAEL 265

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2317 RELTSRLHDEINAKEQKIiSLLSGKEEAIQLAVEELHQQHSKEIKELENLLSQEEEENVALEEENKRALEKTNQLTEALE 2396
Cdd:COG1196    266 EAELEELRLELEELELEL-EEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEE 344

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2397 AIKkesfEQKAQLDSFVKSMSSLQDDRDRIVSDYRQLEERHLSAILEKDQLIQDAAAENNKLKEemrgLRSHMDDLNSEN 2476
Cdd:COG1196    345 ELE----EAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEE----LEEAEEALLERL 416

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2477 AKLDAELVQYRRDLNEVIAIKDSQQKQLLDAQLQQNKELRNECTKLEERLKGLEAEKQSLQMSSDALQKEKQGLSKEikN 2556
Cdd:COG1196    417 ERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARL--L 494

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2557 LQTQLTALQEEGTLGVYHAQLKAKEEEL-QRLNMALSSSQKRTADLEEELVCVQKEATRKVSEIEDQLKKELKHlhHDAG 2635
Cdd:COG1196    495 LLLEAEADYEGFLEGVKAALLLAGLRGLaGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKA--AKAG 572

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2636 IMRNETETAEERVAELARDLVEMEQKLLTVTKENKDLMAQIQAFGRSMSSLQDSRDHATEELGDLKKKYDASLKELAQLK 2715
Cdd:COG1196    573 RATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLE 652

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2716 EWQDSSREGDVLSQAAFPLSTSENVLSRLEKLNQQLTSKDEQLLHLSSELESSHNQVQSISKAMTSLQNERDRLWSELEK 2795
Cdd:COG1196    653 GEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEA 732

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*..
gi 1039751022 2796 FRKSEEGKQRAAAPSAASSPAEVQSLKKAMSSLQNDRDRLLKELKNL 2842
Cdd:COG1196    733 EREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEAL 779
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 2053-2630 7.34e-09

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 61.57  E-value: 7.34e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2053 KELQSNKESIKSQIKQKdEDLLRRLEQAEEKHRKEKKNMQEKLdalhrekahveETLAEIQVSLTRKDQEMKELQGSLDS 2132
Cdd:TIGR04523   36 KQLEKKLKTIKNELKNK-EKELKNLDKNLNKDEEKINNSNNKI-----------KILEQQIKDLNDKLKKNKDKINKLNS 103

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2133 TLAQLAAFTKSMSSLQDDRDRVIDEAKKWERRFGDAIQTKEEEVRLKEENCIALKDQLRQMAIHMEELKITVSRLEHDKE 2212
Cdd:TIGR04523  104 DLSKINSEIKNDKEQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKL 183

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2213 IWESK-AQTELQHHQKAY-----DKLQEENKELTSQLEDARQLYHDSKNELTKLESELKSLKDQTTDLNNSLEKCKEHEN 2286
Cdd:TIGR04523  184 NIQKNiDKIKNKLLKLELllsnlKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQN 263

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2287 NLEGIIKQQEADIQNCKFSCEQLETDLaasRELTSRLHDEINAKEQKIISLLSGKEEAIQLAVEELHQQHSKEIKELENL 2366
Cdd:TIGR04523  264 KIKKQLSEKQKELEQNNKKIKELEKQL---NQLKSEISDLNNQKEQDWNKELKSELKNQEKKLEEIQNQISQNNKIISQL 340

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2367 LSQEEEENVALEEENKRALEKTNQLTE---ALEAIKKESFEQKAQLDSFVKSMSSLQDDRDRIVSDYRQLEERHLSAILE 2443
Cdd:TIGR04523  341 NEQISQLKKELTNSESENSEKQRELEEkqnEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQE 420

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2444 KDQL---IQDAAAENNKLKEEMRGLRSHMDDLNSENAKLDA---ELVQYRRDLNEVIAIKDS---QQKQLLDAQLQQNKE 2514
Cdd:TIGR04523  421 KELLekeIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNtreSLETQLKVLSRSINKIKQnleQKQKELKSKEKELKK 500

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2515 LRNECTKLEERLKGLEAEKQSLQMSSDALQKEKQGLSKEIKNLQTQLTALQEEGTLGVYHAQLKAKEEELQRLNMALSSS 2594
Cdd:TIGR04523  501 LNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDFELKKENLEKEIDEKNKEIEELKQTQKSL 580

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|..
gi 1039751022 2595 QKRTADLEEELVCVQKEATRKVSEIE------DQLKKELKHL 2630
Cdd:TIGR04523  581 KKKQEEKQELIDQKEKEKKDLIKEIEekekkiSSLEKELEKA 622
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 696-1182 7.76e-09

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 61.78  E-value: 7.76e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  696 EEARSTLAAVTEERDQLLYQVKELDVLAELRARVQELESSLAEAEKQRGLDYESQ-RAQHNLLTEQIHSLSIEAKSKDVK 774
Cdd:pfam12128  237 MKIRPEFTKLQQEFNTLESAELRLSHLHFGYKSDETLIASRQEERQETSAELNQLlRTLDDQWKEKRDELNGELSAADAA 316

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  775 IEALQRELDGVQ---LQFCEQG--------TQMKTLQSQLEAKEREVREGTERLRDISQEMEGLSQALSQK-ELEIAKMD 842
Cdd:pfam12128  317 VAKDRSELEALEdqhGAFLDADietaaadqEQLPSWQSELENLEERLKALTGKHQDVTAKYNRRRSKIKEQnNRDIAGIK 396

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  843 QLLlEKQKDVETLQQTIQEKD--QQVTELSFSMTEKMVQLNEEKFSLGVEIKTLKEQLNLLSRTEE--ATKEQVEESGAG 918
Cdd:pfam12128  397 DKL-AKIREARDRQLAVAEDDlqALESELREQLEAGKLEFNEEEYRLKSRLGELKLRLNQATATPEllLQLENFDERIER 475

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  919 SSLKLGHDESGQEGLQQELELLRKESEQRKRKLQAALINRKELLQKVSQLEEEL----AKVREDSRKEIP-FGENERRKL 993
Cdd:pfam12128  476 AREEQEAANAEVERLQSELRQARKRRDQASEALRQASRRLEERQSALDELELQLfpqaGTLLHFLRKEAPdWEQSIGKVI 555

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  994 EEDRENRDD--PEEWgtskwrevEASLKQTISEKEVELEGIRRDLKEKTAAEEELQAVVQRMTRDLQSKTKQIDLLQEEV 1071
Cdd:pfam12128  556 SPELLHRTDldPEVW--------DGSVGGELNLYGVKLDLKRIDVPEWAASEEELRERLDKAEEALQSAREKQAAAEEQL 627

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1072 TENQATIQKLVTGTMDAGNGGSAApvketaassppgaggeehwkpelEGRILDLEKDKTQLQKKLQEALIARKA-ILKKA 1150
Cdd:pfam12128  628 VQANGELEKASREETFARTALKNA-----------------------RLDLRRLFDEKQSEKDKKNKALAERKDsANERL 684

                          490       500       510
                   ....*....|....*....|....*....|..
gi 1039751022 1151 QEKEKQLKEELREQKDAYHHLQGQFHEQNKEK 1182
Cdd:pfam12128  685 NSLEAQLKQLDKKHQAWLEEQKEQKREARTEK 716
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1557-2153 1.00e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 61.49  E-value: 1.00e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1557 EKHKELQKEYEVLlqsyenvsnEAERIQHVVESVRQEKQELyaklrSTESDKREREKQLQDAEQEMEEMKEKMRKfaKSK 1636
Cdd:COG1196    213 ERYRELKEELKEL---------EAELLLLKLRELEAELEEL-----EAELEELEAELEELEAELAELEAELEELR--LEL 276

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1637 QQKILELEEENDRLRAEAQPVGGTGESMEALLSSNSSLKEELEKITLEHKTLSKEFEALMAEKDALSEETRNLKLQVEAQ 1716
Cdd:COG1196    277 EELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEA 356

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1717 VLKQASLEATEKSDEpKDVIEEVTQAVVGKSQERDALSDSAKLEdseailmgdgakpgvsetfsshDDIKNYLQQLDQLK 1796
Cdd:COG1196    357 EAELAEAEEALLEAE-AELAEAEEELEELAEELLEALRAAAELA----------------------AQLEELEEAEEALL 413

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1797 GRIAELEMEKQKDRELSQALENEKNALLTQISAKDSELKLLEEEVTKRTTLNQQIQEELCRVTKLKETAEEEKDDLEERL 1876
Cdd:COG1196    414 ERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARL 493

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1877 mNQLAELNGSIGNYYQDVTDAQIKNEQ--LESEMRNLQRCVSELEEE---------KQQLVKEKTKVESEIRKEYMEKIQ 1945
Cdd:COG1196    494 -LLLLEAEADYEGFLEGVKAALLLAGLrgLAGAVAVLIGVEAAYEAAleaalaaalQNIVVEDDEVAAAAIEYLKAAKAG 572

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1946 GAQKGPANKSHAKELQELLREKQQEVKQLqkDCIRYLERISALEKTVKALEFVHTESQKDLDVTKGNLAQAVEHRKKAQA 2025
Cdd:COG1196    573 RATFLPLDKIRARAALAAALARGAIGAAV--DLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVT 650

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2026 ELSSFKILLDDTQSEAARVLADNLKLKKELQSNKESIKSQIKQKDEDLLRRLEQAEEKHRKEKKNMQEKLDALHREKAHV 2105
Cdd:COG1196    651 LEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQL 730

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*...
gi 1039751022 2106 EETLAEIQVSLTRKDQEMKELQGSLDSTLAQLAAFTKSMSSLQDDRDR 2153
Cdd:COG1196    731 EAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEA 778
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1120-1887 1.05e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 61.61  E-value: 1.05e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1120 GRILDLEKDKTQLQKKLQEALIARKAILKKAQEKEKQLKE---ELREQKDAYHHLQGQFHEQNKEKENIADQLRQLQCQA 1196
Cdd:TIGR02168  232 LRLEELREELEELQEELKEAEEELEELTAELQELEEKLEElrlEVSELEEEIEELQKELYALANEISRLEQQKQILRERL 311

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1197 RESIDRQLPGTGQQEPGPPAPSLEGISLEDTEPASEsdlhaaqpsppgetaalQATVSVAQIQAQLKEMEVEKEELELKV 1276
Cdd:TIGR02168  312 ANLERQLEELEAQLEELESKLDELAEELAELEEKLE-----------------ELKEELESLEAELEELEAELEELESRL 374

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1277 SSIASELAKKSEEVLLLQDQINEQGLEIQNLKAASVEAQAHTELLKQELEsSQLKVAGLEHLKTLQPELDALHKHMGQKE 1356
Cdd:TIGR02168  375 EELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIE-ELLKKLEEAELKELQAELEELEEELEELQ 453

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1357 EEVNYLYGQLSEKEQTLTTVQTEMVEQERLIKALHTQLEMqAKEHEERLKQAQVEICELKKKPTELEEETNAKQQ----- 1431
Cdd:TIGR02168  454 EELERLEEALEELREELEEAEQALDAAERELAQLQARLDS-LERLQENLEGFSEGVKALLKNQSGLSGILGVLSElisvd 532

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1432 ----------LQRKLQAALISRKEALKENKSLQEQLSSARDAVERLTkSLADVESQVSVQN--QEKDAVLGKLTILQEER 1499
Cdd:TIGR02168  533 egyeaaieaaLGGRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLD-SIKGTEIQGNDREilKNIEGFLGVAKDLVKFD 611

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1500 DKLIAEMDRFLlenqSLSGSCESLKLALGGLTEDKEKLM-------------------EELESVRSSKMAESTEWQEKHK 1560
Cdd:TIGR02168  612 PKLRKALSYLL----GGVLVVDDLDNALELAKKLRPGYRivtldgdlvrpggvitggsAKTNSSILERRREIEELEEKIE 687

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1561 ELQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQELYAKLRSTESDKREREKQLQDAEQEMEEMKEKMRKFAKSKQQKI 1640
Cdd:TIGR02168  688 ELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELE 767

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1641 LELEEENDRLRAEAQPVGGTGESMEALLSSNSSLKEELEKITLEHKTLSKEFEAL-----MAEKDALSEETRNLKLQVEA 1715
Cdd:TIGR02168  768 ERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLrerleSLERRIAATERRLEDLEEQI 847

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1716 QVLKQASLEATEKSDEPKDVIEEVTQAVVGKSQERDALSDSAKLEDSEAILMGDGAKpgvsetfSSHDDIKNYLQQLDQL 1795
Cdd:TIGR02168  848 EELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELR-------ELESKRSELRRELEEL 920

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1796 KGRIAELEMEKQKdrelsqaLENEKNALLTQISAKDS-ELKLLEEEVTKRTTLNQQIQEELCRVT-KLKE------TAEE 1867
Cdd:TIGR02168  921 REKLAQLELRLEG-------LEVRIDNLQERLSEEYSlTLEEAEALENKIEDDEEEARRRLKRLEnKIKElgpvnlAAIE 993

                          810       820
                   ....*....|....*....|...
gi 1039751022 1868 EKDDLEER---LMNQLAELNGSI 1887
Cdd:TIGR02168  994 EYEELKERydfLTAQKEDLTEAK 1016
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 892-1597 1.52e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 60.72  E-value: 1.52e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  892 KTLKEQLNLLSRTEEATK-EQVEESGAGSSLKLGHDESGQEGLQQELELLRKESEQRKRKLQAALINRKELLQKVSQLEE 970
Cdd:COG1196    216 RELKEELKELEAELLLLKlRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLA 295

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  971 ELAKVREDSRKEipfgeNERRKLEEDRENRDDPEEwgtSKWREVEASLKQTISEKEVELEGIRRDLKEKTAAEEELQAVV 1050
Cdd:COG1196    296 ELARLEQDIARL-----EERRRELEERLEELEEEL---AELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEAL 367

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1051 QRMTRDLQSKTKQIDLLQEEVTENQATIQklvtgtmdagnggsaapvketaassppgaggeehwkpELEGRILDLEKDKT 1130
Cdd:COG1196    368 LEAEAELAEAEEELEELAEELLEALRAAA-------------------------------------ELAAQLEELEEAEE 410

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1131 QLQKKLQEALIARKAILKKAQEKEKQLKEELREQKDAYHHLQGQFHEQNKEKENIADQLRQLQCQARESIDRQLPgtgqq 1210
Cdd:COG1196    411 ALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEE----- 485

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1211 epgppapslegislEDTEPASESDLHAAQPSPPGETAALQATVSVAQIQAQLKEMEVEKEELELKVSSIASELAkkseev 1290
Cdd:COG1196    486 --------------LAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALA------ 545

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1291 lllqdqineqGLEIQNLKAASVEAQAHTELLKQELESsqlKVAGLEHLKTLQPELDALHKHMGQKEEEVNYLYGQLSEKE 1370
Cdd:COG1196    546 ----------AALQNIVVEDDEVAAAAIEYLKAAKAG---RATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREAD 612

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1371 QTLTTVQTEMVEQERLIKALHT-QLEMQAKEHEERLKQAQVEICELKKKPTELEEETNAKQQLQRKLQAALISRKEAlKE 1449
Cdd:COG1196    613 ARYYVLGDTLLGRTLVAARLEAaLRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLA-EE 691

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1450 NKSLQEQLSSARDAVERLTKSLADVESQVSVQNQEKDAVLGKLTILQEERDKLIAEMDRFLLENQSLSGSCESLKLALGG 1529
Cdd:COG1196    692 ELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELER 771

                          650       660       670       680       690       700
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1039751022 1530 LTEDkeklMEELESVRSskMAEstewqEKHKELQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQEL 1597
Cdd:COG1196    772 LERE----IEALGPVNL--LAI-----EEYEELEERYDFLSEQREDLEEARETLEEAIEEIDRETRER 828
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1279-1803 7.55e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 58.41  E-value: 7.55e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1279 IASELAKKSEEVLLLQDQINEQGLEIQNLKAASVEAQAHTELLKQELESSQlkvAGLEHLKTLQPELDALHKHMGQKEEE 1358
Cdd:COG1196    251 LEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLE---QDIARLEERRRELEERLEELEEELAE 327

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1359 VNYLYGQLSEKEQTLTTVQTEMVEQERLIKALHTQLEMQAKEHEERLKQAQVEICELKKkptELEEETNAKQQLQRKLQA 1438
Cdd:COG1196    328 LEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAE---ELLEALRAAAELAAQLEE 404

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1439 ALISRKEALKENKSLQEQLSSARDAVERLTKSLADVESQVSVQNQEKDAVLGKLTILQEERDKLIAEMDRFLLENQSLSG 1518
Cdd:COG1196    405 LEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLE 484

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1519 SCESLKLALGGLTEDKEKLMEELESVRSSKMAEST--------EWQEKHKELQKEYEVLLQSY------ENVSNEAERIQ 1584
Cdd:COG1196    485 ELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLrglagavaVLIGVEAAYEAALEAALAAAlqnivvEDDEVAAAAIE 564

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1585 HVVESV--RQEKQELYAKLRSTESDKREREKQLQDAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEAQPVGGTGE 1662
Cdd:COG1196    565 YLKAAKagRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAG 644

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1663 SMEALLSSNSSLKEELEKITLEHKTLSKEFEALMAEKDALSEETRNLKLQVEAQVLKQASLEATEKSDEPKDVIEEVTQA 1742
Cdd:COG1196    645 RLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEE 724

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1039751022 1743 VVGKSQERDALSDSAKLEDSEAILMGDGAKPGVSEtfsshDDIKNYLQQLDQLKGRIAELE 1803
Cdd:COG1196    725 ALEEQLEAEREELLEELLEEEELLEEEALEELPEP-----PDLEELERELERLEREIEALG 780
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 645-1081 9.89e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 58.02  E-value: 9.89e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  645 HQGELERLKTQVLELETSLHTAEETYKRNLSEKVKEISSLTQLSEEVKESAEEARSTLAAVTEERDQllyqvkeldvLAE 724
Cdd:COG1196    293 LLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAE----------LAE 362

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  725 LRARVQELESSLAEAEKQRgldYESQRAQHNLLTEQIHSLSieakskdvKIEALQRELDGVQLQFCEQGTQMKTLQSQLE 804
Cdd:COG1196    363 AEEALLEAEAELAEAEEEL---EELAEELLEALRAAAELAA--------QLEELEEAEEALLERLERLEEELEELEEALA 431

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  805 AKEREVREGTERLRDISQEMEGLSQALSQKELEIAKMDQLLLEKQKDVETLQQTIQEKDQQVTELsfsmteKMVQLNEEK 884
Cdd:COG1196    432 ELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLL------LEAEADYEG 505

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  885 FSLGVEIKTLKEQLNLLS------RTEEATKEQVEESGAGSSLKLGHDESGQEGLQQeLELLRKESEQRKRKLQAALINR 958
Cdd:COG1196    506 FLEGVKAALLLAGLRGLAgavavlIGVEAAYEAALEAALAAALQNIVVEDDEVAAAA-IEYLKAAKAGRATFLPLDKIRA 584

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  959 KELLQKVSQLEEELAKVREDSRKEIPFGENERRKLEEDRENRDDPEEWGTSKWREVEASLKQTISEKEVELEGIRRDLKE 1038
Cdd:COG1196    585 RAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTG 664

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|...
gi 1039751022 1039 KTAAEEELQAVVQRMTRDLQSKTKQIDLLQEEVTENQATIQKL 1081
Cdd:COG1196    665 GSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEER 707
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 117-476 1.60e-07

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 57.37  E-value: 1.60e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  117 LQEKEKLISSLQAQLDqsEQASQLDKSSAEMEDfvlMKQQLQEKEELISTLQTQLSQTQAEQAAQlssmqqvvREKDARF 196
Cdd:TIGR02168  672 ILERRREIEELEEKIE--ELEEKIAELEKALAE---LRKELEELEEELEQLRKELEELSRQISAL--------RKDLARL 738

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  197 ETQVRLHEDELLQLvtqSDVETEMQQKLRVMQRKLEEHEEALLGRAQVVDLLQKELTSAEQRNQVLSQQLQLLEAEHNTL 276
Cdd:TIGR02168  739 EAEVEQLEERIAQL---SKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLL 815

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  277 KntmeTERQESKTLMEKVELEVAERKLSFHNLQEEMHQLQGQLERAGQAQADLETQYSALQQRHKTEMEEKTACILSLQK 356
Cdd:TIGR02168  816 N----EEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALAL 891

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  357 NEQELQSACAALKEENSKL--LQEKHDQAAESAQAMRQLEDQLQQKSKEISQFVNKpnlqknetASQTSLPDVNNEGDQA 434
Cdd:TIGR02168  892 LRSELEELSEELRELESKRseLRRELEELREKLAQLELRLEGLEVRIDNLQERLSE--------EYSLTLEEAEALENKI 963

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*.
gi 1039751022  435 VMEEtvASLQKRVVELENEKGAL----LLSSGELEELKAENEKLSS 476
Cdd:TIGR02168  964 EDDE--EEARRRLKRLENKIKELgpvnLAAIEEYEELKERYDFLTA 1007
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1785-2556 2.30e-07

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 56.90  E-value: 2.30e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1785 IKNYLQQLDQLKGRIAELEMEKQKDRELSQALENEKNALLTQISAKDSELKLLEEEVTKRttlnQQIQEELCRVTKLKET 1864
Cdd:pfam02463  281 KKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEEL----EKELKELEIKREAEEE 356

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1865 AEEEKDDLEERLMNQLAELNGSIGNYYQDVTDAQIKNEQLESEMRNLQRCVS---ELEEEKQQLVKEKTKVESEIRKEYM 1941
Cdd:pfam02463  357 EEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQlllELARQLEDLLKEEKKEELEILEEEE 436

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1942 EKIQGAQKGPANKSHAKELQELLREKQQEVKQLQKDcirylerisalektvkalefvhtesqkdldvtKGNLAQAVEHRK 2021
Cdd:pfam02463  437 ESIELKQGKLTEEKEELEKQELKLLKDELELKKSED--------------------------------LLKETQLVKLQE 484

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2022 KAQAELSSFKILLDDTQSEAARVLADNLKLKKELQSNKESIKSQIKQKDEDLLRRLEQAEEKHRKEKKNMQEKLDALHRE 2101
Cdd:pfam02463  485 QLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQ 564

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2102 KAHVEETLAEIQVSLTRKDQEMKELQGSLDSTLAQLAAfTKSMSSLQDDRDRVIDEAKKWERRFGDAIQTKEEEVRLKEE 2181
Cdd:pfam02463  565 KLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPI-LNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKA 643

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2182 NCIALKDQLRQMAIHMEELKITVSRLEHDKEIWESKAQTELQHHQKAYDKLQEENKELTSQLEDARQLYHDSKNELTKLE 2261
Cdd:pfam02463  644 KESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELL 723

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2262 SELKSLKDQTTDLNNSLEKCKEHENNLEGIIKQQEADIQNCKFSCEQLETDLAASReltsRLHDEINAKEQKIISLLSGK 2341
Cdd:pfam02463  724 ADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEE----REKTEKLKVEEEKEEKLKAQ 799

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2342 EEAIQLAVEELHQQHSKEIKELENLLSQEEEENVALEEENKRALEKTNQLTEALEAIKKESFEQKAQLDSFVKSMSSLQD 2421
Cdd:pfam02463  800 EEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEEL 879

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2422 DRDRIVsDYRQLEERHLSAILEKDQLIQDAAAENNKLKEEMRGLRSHMDDLNSENAKLDAELVQYRRDLNEVIAIKDSQQ 2501
Cdd:pfam02463  880 EEQKLK-DELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEE 958

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1039751022 2502 KQLLDAQLQQNKELRN-------ECTKLEERLKGLEAEKQSLQMSSDALQKEKQGLSKEIKN 2556
Cdd:pfam02463  959 EERNKRLLLAKEELGKvnlmaieEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQRLK 1020
PTZ00121 PTZ00121
MAEBL; Provisional
 927-1655 3.79e-07

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 56.30  E-value: 3.79e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  927 ESGQEGLQQELELLRKESEQRKRKLQAALINRKELLQKVSQLEEElAKVREDSRKEIPFGENERRKLEEDRENRDDPEEW 1006
Cdd:PTZ00121  1101 EEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEA-RKAEDAKRVEIARKAEDARKAEEARKAEDAKKAE 1179

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1007 GTSKWREVEASLKQTISEKEVELEGIRRDLKEKTAAE---EELQAVVQRMTRDLQSKTKQIDLLQEEVTENQATIQKLVT 1083
Cdd:PTZ00121  1180 AARKAEEVRKAEELRKAEDARKAEAARKAEEERKAEEarkAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEE 1259

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1084 GTMDAGNGGSAAPVKETAASSPPGAGGEEHWKPElEGRILDLEKDKTQLQKKLQEALIARKAiLKKAQEKEKQ---LKEE 1160
Cdd:PTZ00121  1260 ARMAHFARRQAAIKAEEARKADELKKAEEKKKAD-EAKKAEEKKKADEAKKKAEEAKKADEA-KKKAEEAKKKadaAKKK 1337

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1161 LREQKDAYHHLQGQFHEQNKEKENIADQLRQLQCQARESIDRQLPGTGQQEPGPPAPSLEGISLEDTEPASESDLHAAQP 1240
Cdd:PTZ00121  1338 AEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAK 1417

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1241 SPPGETAALQATVSVAQiqaqlkemeveKEELELKVSSIASELAKKSEEvlllqdqineqGLEIQNLKAASVEAQAHTEL 1320
Cdd:PTZ00121  1418 KKADEAKKKAEEKKKAD-----------EAKKKAEEAKKADEAKKKAEE-----------AKKAEEAKKKAEEAKKADEA 1475

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1321 LKQELESSQlkvagLEHLKTLQPELDALHKHMGQKEEEVNYLyGQLSEKEQTLTTVQTEMVEQERliKALHTQLEMQAKE 1400
Cdd:PTZ00121  1476 KKKAEEAKK-----ADEAKKKAEEAKKKADEAKKAAEAKKKA-DEAKKAEEAKKADEAKKAEEAK--KADEAKKAEEKKK 1547

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1401 HEERLKQAQVEICELKKKPTELEEETNAKQQLQRKLQAALISRKEALKENKSLQEQLSSARDAVERLTKSLADVESQVSV 1480
Cdd:PTZ00121  1548 ADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKK 1627

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1481 QNQEKDAVLGKLTILQEERDKliAEMDRFLLENQSLSGSCESLKLALGGLTEDKEKLMEELESVRSSKMAESTEWQEKHK 1560
Cdd:PTZ00121  1628 AEEEKKKVEQLKKKEAEEKKK--AEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAE 1705

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1561 ELQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQELYAKLRSTESDKREREKQLQDAEQEMEEMKEKMRKFAKSKQQki 1640
Cdd:PTZ00121  1706 ELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEE-- 1783

                          730
                   ....*....|....*
gi 1039751022 1641 lELEEENDRLRAEAQ 1655
Cdd:PTZ00121  1784 -ELDEEDEKRRMEVD 1797
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1900-2631 6.49e-07

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 55.36  E-value: 6.49e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1900 KNEQLESEMRNLQRCVSELEEEKQQLVKEKTKVESEIRKEY-MEKIQGAQKGPANKSHAKELQELLREKQQEVKQLQKDC 1978
Cdd:pfam02463  174 ALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQlKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEI 253

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1979 IRYLERISALEKTVKALEFVHTESQKDLDVTKGNLAQAVEHRKKAQAELSSFKILLDDTQSEAARVLADNLKLKKELQSN 2058
Cdd:pfam02463  254 ESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKE 333

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2059 KESIKSQIKQKDEDLLRRLEQAEEKhrkekknmqEKLDALHREKAHVEETLAEIQvsltRKDQEMKELQGSLDSTLAQLA 2138
Cdd:pfam02463  334 KEEIEELEKELKELEIKREAEEEEE---------EELEKLQEKLEQLEEELLAKK----KLESERLSSAAKLKEEELELK 400

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2139 AFTKSMSSLQDDRDRVIDEAKKWERRFGDAIQTKEEEVRLKEENCIALKDQLRQMAIHMEELKITVSRLEHDKEIWESKA 2218
Cdd:pfam02463  401 SEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLV 480

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2219 QTELQHHQKAYDKLQEENKELTSQLEDARQLYHDSKNELTKLESELKSLKdqTTDLNNSLEKCKEHENNLEGIIKQQEAD 2298
Cdd:pfam02463  481 KLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGR--LGDLGVAVENYKVAISTAVIVEVSATAD 558

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2299 IQNCKFSCEQLETDLAASRELTSRLHDEINAKEQKIISL-------LSGKEEAIQLAVEELHQQHSKEIKELENLLSQEE 2371
Cdd:pfam02463  559 EVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLeidpilnLAQLDKATLEADEDDKRAKVVEGILKDTELTKLK 638

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2372 EENVALEEENKRALEKTNQLTEALEAIKKESFEQKAQLDSFVKSMSSLQDdrdrivsdyrQLEERHLSAILEKDQLIQDA 2451
Cdd:pfam02463  639 ESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESE----------LAKEEILRRQLEIKKKEQRE 708

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2452 AAENNKLKEEMRGLRSHMDDLNSENAKLDAELVQYRRDLN----EVIAIKDSQQKQLLDAQLQQNKELRNECTKLEERLK 2527
Cdd:pfam02463  709 KEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEeeeeEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKV 788

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2528 GLEAEKQSLQMSSDALQKEKQGLSKEIKNLQTQLTALQEEGTLGVYHAQLKAKEEELQRLNMALSSSQKRTADLEEELVC 2607
Cdd:pfam02463  789 EEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEEL 868

                          730       740
                   ....*....|....*....|....
gi 1039751022 2608 VQKEATRKVSEIEDQLKKELKHLH 2631
Cdd:pfam02463  869 LQELLLKEEELEEQKLKDELESKE 892
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
2421-2700 6.96e-07

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 55.31  E-value: 6.96e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2421 DDRDRIVSDYrQLEERHLSAILEKDQLIQDAAAENNKLKEEMRGLRSHMDDLNSENAKLdAELVQYRRDLNEViaikDSQ 2500
Cdd:COG4913    593 DDRRRIRSRY-VLGFDNRAKLAALEAELAELEEELAEAEERLEALEAELDALQERREAL-QRLAEYSWDEIDV----ASA 666

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2501 QKQL--LDAQLQQNKELRNECTKLEERLKGLEAEKQSLQMSSDALQKEKQGLSKEIKNLQTQLTALQ---EEGTLGVYHA 2575
Cdd:COG4913    667 EREIaeLEAELERLDASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQdrlEAAEDLARLE 746

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2576 QLKAKEEELQRLNMALSSSQKRtADLEEELVCVQKEATRKVSEIEDQLKKELKHLHHDAGIMRNETETAEERVAELAR-- 2653
Cdd:COG4913    747 LRALLEERFAAALGDAVERELR-ENLEERIDALRARLNRAEEELERAMRAFNREWPAETADLDADLESLPEYLALLDRle 825

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2654 --DLVEMEQKLLT-VTKENKDLMAQIQafgrsmSSLQDSRDHATEELGDL 2700
Cdd:COG4913    826 edGLPEYEERFKElLNENSIEFVADLL------SKLRRAIREIKERIDPL 869
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
693-958 1.24e-06

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 54.25  E-value: 1.24e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  693 ESAEEARSTLAAVTEE--RDQLLYQVKELD-VLAELRARVQELESSLAEAEKQrgldYESQRAQHNLLteqihSLSIEAK 769
Cdd:COG3206    145 PDPELAAAVANALAEAylEQNLELRREEARkALEFLEEQLPELRKELEEAEAA----LEEFRQKNGLV-----DLSEEAK 215

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  770 SKDVKIEALQRELDGVQLQFCEQGTQMKTLQSQLEAKEREVREGTErlrdiSQEMEGLSQALSQKELEIAKMDQLLLEKQ 849
Cdd:COG3206    216 LLLQQLSELESQLAEARAELAEAEARLAALRAQLGSGPDALPELLQ-----SPVIQQLRAQLAELEAELAELSARYTPNH 290

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  850 KDVETLQQTIQEKDQQVTElsfsmtekmvQLNEEKFSLGVEIKTLKEQLNLLSRTEEATKEQVEESGAgsslklghDESG 929
Cdd:COG3206    291 PDVIALRAQIAALRAQLQQ----------EAQRILASLEAELEALQAREASLQAQLAQLEARLAELPE--------LEAE 352

                          250       260
                   ....*....|....*....|....*....
gi 1039751022  930 QEGLQQELELLRKESEQRKRKLQAALINR 958
Cdd:COG3206    353 LRRLEREVEVARELYESLLQRLEEARLAE 381
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 9-272 1.38e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 54.56  E-value: 1.38e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022    9 ESTQEDALHRLAEAEKLVVELKDIISQKDVQLQQKDEALQEEKKAAENKIKKIKlHAKAKIMSLNKHMEEIKTQGgaalp 88
Cdd:COG1196    252 EAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIA-RLEERRRELEERLEELEEEL----- 325

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022   89 pEAQAEELSKHNKSSTEEEMEIEKIKHELQEKEKLISSLQAQLdqSEQASQLDKSSAEMEDFVLMKQQLQEKEELISTLQ 168
Cdd:COG1196    326 -AELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEAL--LEAEAELAEAEEELEELAEELLEALRAAAELAAQL 402

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  169 TQLSQTQAEQAAQLSSMQQVVREKDARFETQVRLHEDELLQLVTQSDVETEMQQKLRVMQRKLEEHEEALLGRAQVVDLL 248
Cdd:COG1196    403 EELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAEL 482

                          250       260
                   ....*....|....*....|....
gi 1039751022  249 QKELTSAEQRNQVLSQQLQLLEAE 272
Cdd:COG1196    483 LEELAEAAARLLLLLEAEADYEGF 506
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 756-977 1.44e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 53.61  E-value: 1.44e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  756 LLTEQIHSLSIEAKSKDVKIEALQRELDGVQLQFCEQGTQMKTLQSQLEAKEREVREGTERLRDISQEMEGLSQALSQKE 835
Cdd:COG4942     10 LLALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELE 89

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  836 LEIAKMDQLLLEKQKDVETLQQTIQEKDQQVTEL----------SFSMTEKMVQLNEEKFSLGVEIKTLKEQLNLLSRTE 905
Cdd:COG4942     90 KEIAELRAELEAQKEELAELLRALYRLGRQPPLAlllspedfldAVRRLQYLKYLAPARREQAEELRADLAELAALRAEL 169

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1039751022  906 EATKEQVEESGAGSSLKLGHDESGQEGLQQELELLRKESEQRKRKLQAALINRKELLQKVSQLEEELAKVRE 977
Cdd:COG4942    170 EAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAE 241
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1293-1735 1.84e-06

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 53.97  E-value: 1.84e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1293 LQDQINEQGLEIQNL----KAASVEAQAHTEllkQELESSQLKVAGLEHLKTLQPELDALHKHMGQKEEEVNYLYGQLSE 1368
Cdd:pfam15921  417 LRRELDDRNMEVQRLeallKAMKSECQGQME---RQMAAIQGKNESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLES 493

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1369 KEQTLTTVQTEMVEQERLIKALHTQLEMQAKEHEERLKQAQveicelkkkptELEEETNAKQQLQRKLQAALISRKEALK 1448
Cdd:pfam15921  494 SERTVSDLTASLQEKERAIEATNAEITKLRSRVDLKLQELQ-----------HLKNEGDHLRNVQTECEALKLQMAEKDK 562

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1449 ENKSLQEQLSSARDAV---ERLTKSLADVESQVSVQNQEKDAVLGKLTILQEERDKLIAEmdrflLENQSLSGSCESLKL 1525
Cdd:pfam15921  563 VIEILRQQIENMTQLVgqhGRTAGAMQVEKAQLEKEINDRRLELQEFKILKDKKDAKIRE-----LEARVSDLELEKVKL 637

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1526 ALGGltEDKEKLMEELESVRSSKMAESTEWQEKHKELQKEYEVLLQSYENVSNEAERIQHvvesvrqekqELYAKLRSTE 1605
Cdd:pfam15921  638 VNAG--SERLRAVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMETTTN----------KLKMQLKSAQ 705

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1606 SDKREREKQLQDAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEAQPVGGTGESMEALLSSNSSLKEELEKITLEH 1685
Cdd:pfam15921  706 SELEQTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATEK 785

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1686 KTLSKEFEALMAEKDALSEETRNLKLQVEAQVLKQASLEATEKSDEPKDV 1735
Cdd:pfam15921  786 NKMAGELEVLRSQERRLKEKVANMEVALDKASLQFAECQDIIQRQEQESV 835
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1783-2416 2.13e-06

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 53.49  E-value: 2.13e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1783 DDIKNYLQQLDQLKGRIAELEMEKQKDRELSQALENEKNALLTQISAKDSELKLLEEEVTKRTTLNQQIQEELCRVTKLK 1862
Cdd:TIGR04523   89 DKLKKNKDKINKLNSDLSKINSEIKNDKEQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQK 168

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1863 ETAEEEKDDLEERLMNQLAELNGSIGNYYQDVTDAQI------KNEQLESEMRNLQRCVSELEEEKQQLVKEKTKVESEI 1936
Cdd:TIGR04523  169 EELENELNLLEKEKLNIQKNIDKIKNKLLKLELLLSNlkkkiqKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEI 248

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1937 rkeymekiqgaqkgpanKSHAKELQELLREKQQEVKQLQkdcirylerisalektvkalefvhtESQKDLDVTKGNLAQA 2016
Cdd:TIGR04523  249 -----------------SNTQTQLNQLKDEQNKIKKQLS-------------------------EKQKELEQNNKKIKEL 286

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2017 VEHRKKAQAELSsfkillddtqseaarvladNLKLKKELQSNKEsIKSQIKQKDEDlLRRLEQAEEKHRKEKKNMQEKLD 2096
Cdd:TIGR04523  287 EKQLNQLKSEIS-------------------DLNNQKEQDWNKE-LKSELKNQEKK-LEEIQNQISQNNKIISQLNEQIS 345

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2097 ALHREKAHVEETLAEIQVSLTRKDQEMKELQGSLDSTLAQLAAFTKSMSSLQddrdRVIDEAKKWERRFGDAIQTKEEEV 2176
Cdd:TIGR04523  346 QLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLE----SKIQNQEKLNQQKDEQIKKLQQEK 421

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2177 RLKEENCIALKDQLRQMAIHMEELKITVSRLEhdKEIWESKAQTELQhhQKAYDKLQEENKELTSQLEDARQLYHDSKNE 2256
Cdd:TIGR04523  422 ELLEKEIERLKETIIKNNSEIKDLTNQDSVKE--LIIKNLDNTRESL--ETQLKVLSRSINKIKQNLEQKQKELKSKEKE 497

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2257 LTKLESELKSLKDQTTDLNNSLEKCKEHENNLEGIIKQQEADIQNCKFSCEQLETDLAasrelTSRLHDEINAKEQKIIS 2336
Cdd:TIGR04523  498 LKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDFELK-----KENLEKEIDEKNKEIEE 572

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2337 LLSGKE--EAIQLAVEELHQQHSKEIKELENLLSQEEEENVALeeenKRALEKTNQLTEALEAIKKESFEQKAQLDSFVK 2414
Cdd:TIGR04523  573 LKQTQKslKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSL----EKELEKAKKENEKLSSIIKNIKSKKNKLKQEVK 648


                   ..
gi 1039751022 2415 SM 2416
Cdd:TIGR04523  649 QI 650
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 2152-2998 2.83e-06

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 53.58  E-value: 2.83e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2152 DRVIDE----AKKWERRFGDAIQTKEEEVRLKEENCIALKDQLRQMAIHMEELKITVSRLEHDKEIWESKAQTELQHHQK 2227
Cdd:pfam15921   77 ERVLEEyshqVKDLQRRLNESNELHEKQKFYLRQSVIDLQTKLQEMQMERDAMADIRRRESQSQEDLRNQLQNTVHELEA 156

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2228 AYDKLQEENKELTSQLEDARQLYHDSKNELTKLESELKSLKDQttdlnnSLEKCKEHENNLEGIIKQQEADIQNCkfsCE 2307
Cdd:pfam15921  157 AKCLKEDMLEDSNTQIEQLRKMMLSHEGVLQEIRSILVDFEEA------SGKKIYEHDSMSTMHFRSLGSAISKI---LR 227

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2308 QLETDLaasreltSRLHDEINAKEQKIISLLSGKEEAIQLaveeLHQQHSKEIkelENLLSQEEEENVALEEENKRALEK 2387
Cdd:pfam15921  228 ELDTEI-------SYLKGRIFPVEDQLEALKSESQNKIEL----LLQQHQDRI---EQLISEHEVEITGLTEKASSARSQ 293

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2388 TNQLTEALEAIKKESFEQKAQldsFVKSMSSLQDDRDRIVSDYRQLEERHLSAIlekDQLIQDAAAENNKLKEEmrglRS 2467
Cdd:pfam15921  294 ANSIQSQLEIIQEQARNQNSM---YMRQLSDLESTVSQLRSELREAKRMYEDKI---EELEKQLVLANSELTEA----RT 363

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2468 HMDDLNSENAKLDAELVQYRRDLNeviaikdsQQKQLLDAQLQQNKELRNECTkleerlkgleaekqSLQMSSDALQKEK 2547
Cdd:pfam15921  364 ERDQFSQESGNLDDQLQKLLADLH--------KREKELSLEKEQNKRLWDRDT--------------GNSITIDHLRREL 421

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2548 QGLSKEIKNLQTQLTALQEEgtlgvYHAQLKAKEEELQRLNMALSSSQKRTADLEEelvcvQKEATRKVSEIEDQLKKEL 2627
Cdd:pfam15921  422 DDRNMEVQRLEALLKAMKSE-----CQGQMERQMAAIQGKNESLEKVSSLTAQLES-----TKEMLRKVVEELTAKKMTL 491

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2628 khlhhdagimrnetETAEERVAELARDLVEMEQKLltvtkenkdlmaqiqafgrsmsslqdsrDHATEELGDLKKKYDAS 2707
Cdd:pfam15921  492 --------------ESSERTVSDLTASLQEKERAI----------------------------EATNAEITKLRSRVDLK 529

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2708 LKELAQLKEwqdssrEGDVLsqaafplstsENVLSRLEKLNQQLTSKDEQLLHLSSELESSHNQVQSISKAMTSLQNERD 2787
Cdd:pfam15921  530 LQELQHLKN------EGDHL----------RNVQTECEALKLQMAEKDKVIEILRQQIENMTQLVGQHGRTAGAMQVEKA 593

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2788 RLWSE-------LEKFRKSEEGKQ-RAAAPSAASSPAEVQSLK---------KAMSSLQNDRDRLLKELKNLQQQYLQMS 2850
Cdd:pfam15921  594 QLEKEindrrleLQEFKILKDKKDaKIRELEARVSDLELEKVKlvnagserlRAVKDIKQERDQLLNEVKTSRNELNSLS 673

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2851 QEMTELRplkaqlQESQDQTKALQVMEEELRQENLSWQHELRQLRMEKNSWE---LHERRMKEQFLMAISDKDQQLGHLQ 2927
Cdd:pfam15921  674 EDYEVLK------RNFRNKSEEMETTTNKLKMQLKSAQSELEQTRNTLKSMEgsdGHAMKVAMGMQKQITAKRGQIDALQ 747

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1039751022 2928 S----LLRELRSSSQAQILSTQYQRQASPETSASLDGSQKLVYETELLRTQLNDSLKEIHQKELRIQQLNSKFSQ 2998
Cdd:pfam15921  748 SkiqfLEEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANMEVALDKASLQFAE 822
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 648-1071 2.98e-06

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 53.20  E-value: 2.98e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  648 ELERLKTQVLELETSLHTAEETYKRNLsekvkeissltqlsEEVKESAEEARSTLAAVTEERDQLLYQVKELD-----VL 722
Cdd:pfam15921  318 QLSDLESTVSQLRSELREAKRMYEDKI--------------EELEKQLVLANSELTEARTERDQFSQESGNLDdqlqkLL 383

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  723 AELRARVQELesSLAEAEKQRGLDYESQRA-QHNLLTEQIHSLSIEAKSKDVKIEALQRELDGvqlqfcEQGTQMKTLQS 801
Cdd:pfam15921  384 ADLHKREKEL--SLEKEQNKRLWDRDTGNSiTIDHLRRELDDRNMEVQRLEALLKAMKSECQG------QMERQMAAIQG 455

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  802 QLEAKER------EVREGTERLRDISQEMEGLSQALSQKELEIAKMDQLLLEKQKDVETLQQTIQEKDQQVtELSFSMTE 875
Cdd:pfam15921  456 KNESLEKvssltaQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEATNAEITKLRSRV-DLKLQELQ 534

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  876 KMVQLNEEKFSLGVEIKTLKEQLNLLSRTEEATKEQVEESgagsSLKLGHDESGQEGLQQELELLRKESEQRKRKLQAAL 955
Cdd:pfam15921  535 HLKNEGDHLRNVQTECEALKLQMAEKDKVIEILRQQIENM----TQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQEFK 610

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  956 INR-------KELLQKVSQLEEELAKV-----------------REDSRKEIPFGENERRKLEED-----RENRDDPEEW 1006
Cdd:pfam15921  611 ILKdkkdakiRELEARVSDLELEKVKLvnagserlravkdikqeRDQLLNEVKTSRNELNSLSEDyevlkRNFRNKSEEM 690

                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1039751022 1007 GTSKWReveasLKQTISEKEVELEGIRRDLKEKTAAEEELQAVVQRMTRDLQSKTKQIDLLQEEV 1071
Cdd:pfam15921  691 ETTTNK-----LKMQLKSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKI 750
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
2052-2627 3.01e-06

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 53.14  E-value: 3.01e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2052 KKELQSNKESIKSQIKQKDEDLLRRLEQAEEKhRKEKKNMQEKLDALHREKAHVEET---LAEIQVSLTRKDQEMKELQG 2128
Cdd:PRK03918   181 LEKFIKRTENIEELIKEKEKELEEVLREINEI-SSELPELREELEKLEKEVKELEELkeeIEELEKELESLEGSKRKLEE 259

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2129 SLDSTLAQLAAFTKSMSSLQDDRDRVID---EAKKWERRFGDAIQTKEEEVRLKEENCIaLKDQLRQMAIHMEELKITVS 2205
Cdd:PRK03918   260 KIRELEERIEELKKEIEELEEKVKELKElkeKAEEYIKLSEFYEEYLDELREIEKRLSR-LEEEINGIEERIKELEEKEE 338

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2206 RLEhdkeiWESKAQTELQHHQKAYDKLQEENKELTSQLEDARQLYHDSKN-ELTKLESELKSLKDQTTDLNNSLEKCKEH 2284
Cdd:PRK03918   339 RLE-----ELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGlTPEKLEKELEELEKAKEEIEEEISKITAR 413

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2285 ENNLEGIIKQQEADIQNCKFS------CEQLETDlAASRELTSRLHDEINAKEQKIISLLSGKEEAIQLAVE-------- 2350
Cdd:PRK03918   414 IGELKKEIKELKKAIEELKKAkgkcpvCGRELTE-EHRKELLEEYTAELKRIEKELKEIEEKERKLRKELRElekvlkke 492

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2351 -ELHQQHS--KEIKELENLLSQEEEENVALEEENKRAL-EKTNQLTEALEAIKKESFEQKAQLDSFVKSMSSLQDDRDRI 2426
Cdd:PRK03918   493 sELIKLKElaEQLKELEEKLKKYNLEELEKKAEEYEKLkEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEEL 572

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2427 VSDYRQLEERHLSAILEKDQLIQDAAAENNKLKEeMRGLRSHMDDLNSENAKLDAELVQYRRDLNEVIAIKDSQQKQLLD 2506
Cdd:PRK03918   573 AELLKELEELGFESVEELEERLKELEPFYNEYLE-LKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEE 651

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2507 AQLQQNKE----LRNECTKLEERLKGLEAEKQSlqmssdaLQKEKQGLSKEIKNLQTQLTALQEegtlgvyhaqlkaKEE 2582
Cdd:PRK03918   652 LEKKYSEEeyeeLREEYLELSRELAGLRAELEE-------LEKRREEIKKTLEKLKEELEEREK-------------AKK 711

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*
gi 1039751022 2583 ELQRLNMALSSSQKRTADLEEELVCVQKEATRKVSEIEDQLKKEL 2627
Cdd:PRK03918   712 ELEKLEKALERVEELREKVKKYKALLKERALSKVGEIASEIFEEL 756
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
2074-2672 3.51e-06

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 53.14  E-value: 3.51e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2074 LRRLEQAEEKHRKEKKNMQEKLDALHRE---KAHVEETLAEIQVSLTRKDQEMKELQGSLDSTLAQLAAFTKSMSSLQDD 2150
Cdd:PRK03918   157 LDDYENAYKNLGEVIKEIKRRIERLEKFikrTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEEL 236

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2151 RDRVIDEAKKWERRFGDAiqtKEEEVRLKEenciaLKDQLRQMAIHMEELKITVSRLEhdkeiweskaqtELQHHQKAYD 2230
Cdd:PRK03918   237 KEEIEELEKELESLEGSK---RKLEEKIRE-----LEERIEELKKEIEELEEKVKELK------------ELKEKAEEYI 296

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2231 KLQEENKELTSQLEDArqlyhdsKNELTKLESELKSLKDQTTDLNNSLEKCKEHENNLEGIIKQQEAdIQNCKFSCEQLE 2310
Cdd:PRK03918   297 KLSEFYEEYLDELREI-------EKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEE-LEERHELYEEAK 368

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2311 TDLAASRELTSRLHDEINAKEQKIISLLSGKEEAIQLAVEELHQqhskEIKELENLLSQEEEENVALEEENKRALEKTNQ 2390
Cdd:PRK03918   369 AKKEELERLKKRLTGLTPEKLEKELEELEKAKEEIEEEISKITA----RIGELKKEIKELKKAIEELKKAKGKCPVCGRE 444

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2391 LTEAleaikkesfEQKAQLDSFVKSMSSLQDDRDRIVSDYRQLEERHLSaiLEKDQLIQDAAAENNKLKEEMRGLRSHMD 2470
Cdd:PRK03918   445 LTEE---------HRKELLEEYTAELKRIEKELKEIEEKERKLRKELRE--LEKVLKKESELIKLKELAEQLKELEEKLK 513

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2471 DLNSENAKLDAElvQYRRDLNEVIAIKdSQQKQLLDaQLQQNKELRNECTKLEERLKGLEAEKQSLQ--------MSSDA 2542
Cdd:PRK03918   514 KYNLEELEKKAE--EYEKLKEKLIKLK-GEIKSLKK-ELEKLEELKKKLAELEKKLDELEEELAELLkeleelgfESVEE 589

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2543 LQKEKQGLSK------EIKNLQTQLTALQEEgtLGVYHAQLKAKEEELQRLNMALSSSQKRtadLEEELVCVQKEATRKV 2616
Cdd:PRK03918   590 LEERLKELEPfyneylELKDAEKELEREEKE--LKKLEEELDKAFEELAETEKRLEELRKE---LEELEKKYSEEEYEEL 664

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1039751022 2617 SEIEDQLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLTVTKENKDL 2672
Cdd:PRK03918   665 REEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKAKKELEKLEKAL 720
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
679-914 3.89e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 53.00  E-value: 3.89e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  679 KEISSLTQL-------SEEVKESAEEARSTLAAVTEERDQLLYQVKELDVLAELRARVQELESSLAEAEKQRGLD----- 746
Cdd:COG4913    204 KPIGDLDDFvreymleEPDTFEAADALVEHFDDLERAHEALEDAREQIELLEPIRELAERYAAARERLAELEYLRaalrl 283

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  747 YESQRAQHNL------LTEQIHSLSIEAKSKDVKIEALQRELDGVQLQFCEQGTQmktlqsQLEAKEREVREGTERLRDI 820
Cdd:COG4913    284 WFAQRRLELLeaeleeLRAELARLEAELERLEARLDALREELDELEAQIRGNGGD------RLEQLEREIERLERELEER 357

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  821 SQEMEGLSQALSQKELEIAKMDQLLLEKQKDVETLQQTIQEKDQQVTELSFSMTEKMVQLNEEKFSLGVEIKTLKEQLNL 900
Cdd:COG4913    358 ERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSN 437

                          250
                   ....*....|....
gi 1039751022  901 LSRTEEATKEQVEE 914
Cdd:COG4913    438 IPARLLALRDALAE 451
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 1368-2172 3.89e-06

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 52.92  E-value: 3.89e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1368 EKEQTLTTVQTEMVE--QERLIKALHTQLEMQAKEHEERLKQAQVEICELKKKPTELEEETNAKQQLQRKLQAALISRKE 1445
Cdd:pfam12128  190 SKEGKFRDVKSMIVAilEDDGVVPPKSRLNRQQVEHWIRDIQAIAGIMKIRPEFTKLQQEFNTLESAELRLSHLHFGYKS 269

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1446 ALKENKSLQEQLSSARDAVERLTKSL-ADVESQVSVQNQEKDAVLGKLTILQEERDKLIAEMDRFLLENqslsgsCESLK 1524
Cdd:pfam12128  270 DETLIASRQEERQETSAELNQLLRTLdDQWKEKRDELNGELSAADAAVAKDRSELEALEDQHGAFLDAD------IETAA 343

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1525 LALggltedkeklmEELESVRS--SKMAESTEWQE-KHKELQKEYEVLLQsyeNVSNEAERIQHVVESVRQEKQELYAKL 1601
Cdd:pfam12128  344 ADQ-----------EQLPSWQSelENLEERLKALTgKHQDVTAKYNRRRS---KIKEQNNRDIAGIKDKLAKIREARDRQ 409

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1602 RSTESDKRER-EKQLQDaeqemeEMKEKMRKFAKSKQQKILELEEENDRLrAEAQPVGGTGESMEALLSSNSSLKEELEK 1680
Cdd:pfam12128  410 LAVAEDDLQAlESELRE------QLEAGKLEFNEEEYRLKSRLGELKLRL-NQATATPELLLQLENFDERIERAREEQEA 482

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1681 ITLEHKTLSKEFEALMAEKDALSEETRNLKLQVEAQVLKQASLEaTEKSDEPKDVIEEVTQAVVGKSQERDALSDSAKLE 1760
Cdd:pfam12128  483 ANAEVERLQSELRQARKRRDQASEALRQASRRLEERQSALDELE-LQLFPQAGTLLHFLRKEAPDWEQSIGKVISPELLH 561

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1761 DSEAILMGDGAKPGVSETFSS------HDDIKNYLQQLDQLKGRIAELEMEKQKDRELSQALENEknalLTQISAKDSEL 1834
Cdd:pfam12128  562 RTDLDPEVWDGSVGGELNLYGvkldlkRIDVPEWAASEEELRERLDKAEEALQSAREKQAAAEEQ----LVQANGELEKA 637

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1835 KLleEEVTKRTTLnQQIQEELCRVT--------KLKETAEEEKDDLEERLMNQLAELNgSIGNYYQDVTdAQIKNEQLES 1906
Cdd:pfam12128  638 SR--EETFARTAL-KNARLDLRRLFdekqsekdKKNKALAERKDSANERLNSLEAQLK-QLDKKHQAWL-EEQKEQKREA 712

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1907 EMRNLQRCVSELEEEKQQLVKEKTKVESEirkeymekiqgaqkgpaNKSHAKELQELLREKQQEVKQLQKDCirylERIS 1986
Cdd:pfam12128  713 RTEKQAYWQVVEGALDAQLALLKAAIAAR-----------------RSGAKAELKALETWYKRDLASLGVDP----DVIA 771

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1987 ALEKTVKalefvhtesqkdldvtkgNLAQAVEHRKKAQAELSSFKILLDDTQSEAARVLADNLklkKELQSNKESIKSQI 2066
Cdd:pfam12128  772 KLKREIR------------------TLERKIERIAVRRQEVLRYFDWYQETWLQRRPRLATQL---SNIERAISELQQQL 830

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2067 KQKDEDLLRRLeQAEEKHRKEKKNMQEKLDALHREKAHVEETLAEIQVsltrkDQEMKELQGSLDSTLAQLaaftksmSS 2146
Cdd:pfam12128  831 ARLIADTKLRR-AKLEMERKASEKQQVRLSENLRGLRCEMSKLATLKE-----DANSEQAQGSIGERLAQL-------ED 897

                          810       820
                   ....*....|....*....|....*.
gi 1039751022 2147 LQDDRDRVIDEAKKWERRFGDAIQTK 2172
Cdd:pfam12128  898 LKLKRDYLSESVKKYVEHFKNVIADH 923
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1414-1618 4.10e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 52.07  E-value: 4.10e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1414 ELKKKPTELEEETNAKQQLQRKLQAALISRKEALKENKSLQEQLSSARDAVERLTKSLADVESQVSVQNQEKDAVLGKLT 1493
Cdd:COG4942     21 AAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELE 100

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1494 ILQEERDKLIAEMDR--------FLLENQSLSGSCESLKLaLGGLTEDKEKLMEELEsvrsskmAESTEWQEKHKELQKE 1565
Cdd:COG4942    101 AQKEELAELLRALYRlgrqpplaLLLSPEDFLDAVRRLQY-LKYLAPARREQAEELR-------ADLAELAALRAELEAE 172

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1039751022 1566 YEVLLQSYENVSNEAERIqhvvESVRQEKQELYAKLRSTESDKREREKQLQDA 1618
Cdd:COG4942    173 RAELEALLAELEEERAAL----EALKAERQKLLARLEKELAELAAELAELQQE 221
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 645-1081 4.27e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 52.63  E-value: 4.27e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  645 HQGELERLKTQVLELETSLHTAEETYKRNLSEKVKEISSLTQLSEEVKESAEEARSTLAAVTEERDQLLYQVKELDVLAE 724
Cdd:COG1196    335 LEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLE 414

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  725 LRARVQELESSLAEAEKQRGLDYESQRAQHNLLTEQIHSLSIEAKSKDVKIEALQRELDGVQLQFCEQGTQMKTLQSQLE 804
Cdd:COG1196    415 RLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLL 494

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  805 AKE-----REVREGTERLRDISQEMEGLSQALS---------QKELEIAKMDQLLLEKQKDVETLQQTIQE-KDQQVTEL 869
Cdd:COG1196    495 LLLeaeadYEGFLEGVKAALLLAGLRGLAGAVAvligveaayEAALEAALAAALQNIVVEDDEVAAAAIEYlKAAKAGRA 574

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  870 SFSMTEKM--VQLNEEKFSLGV---------------EIKTLKEQLNLLSRTEEATK-------------EQVEESGAGS 919
Cdd:COG1196    575 TFLPLDKIraRAALAAALARGAigaavdlvasdlreaDARYYVLGDTLLGRTLVAARleaalrravtlagRLREVTLEGE 654

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  920 SLKLGHDESGQEGLQQELELLRKESEQRKRKLQAALINRKELLQKVSQLEEELAKVREDSRKEIPFGENERRKLEEDREN 999
Cdd:COG1196    655 GGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAER 734

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1000 RDDPEEW-----GTSKWREVEASLKQTISEKEVELEGIRRDLKEK----TAAEEELQAVVQRmtrdLQSKTKQIDLLQEE 1070
Cdd:COG1196    735 EELLEELleeeeLLEEEALEELPEPPDLEELERELERLEREIEALgpvnLLAIEEYEELEER----YDFLSEQREDLEEA 810

                          490
                   ....*....|.
gi 1039751022 1071 VTENQATIQKL 1081
Cdd:COG1196    811 RETLEEAIEEI 821
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 1798-2560 4.35e-06

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 52.74  E-value: 4.35e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1798 RIAELEMEKQKDRELSQALENEKNALLTQISAKDSELKLLEEEVTKRTTLNQQIQEELcrvtklkETAEEEKDDLEERLM 1877
Cdd:TIGR00606  320 ELVDCQRELEKLNKERRLLNQEKTELLVEQGRLQLQADRHQEHIRARDSLIQSLATRL-------ELDGFERGPFSERQI 392

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1878 NQLAELNGSiGNYYQDVTDAQIKNEqLESEMRNLQRCVSELEEEKQQL---VKEKTKVESEIRKEYMEKIQGAQKGPANK 1954
Cdd:TIGR00606  393 KNFHTLVIE-RQEDEAKTAAQLCAD-LQSKERLKQEQADEIRDEKKGLgrtIELKKEILEKKQEELKFVIKELQQLEGSS 470

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1955 SHAKELQELLREKQQEVKQLQKDcirylerisALEKTVKALEFVHTESQKDLDVTKGNLAQAVEHRKKAQAELSSFKILL 2034
Cdd:TIGR00606  471 DRILELDQELRKAERELSKAEKN---------SLTETLKKEVKSLQNEKADLDRKLRKLDQEMEQLNHHTTTRTQMEMLT 541

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2035 DDTQSEAARV-------------LADNLKLKKELQSNKESIKSQIKQKDEDL------LRRLEQAEEKHRKEKKNMQEKL 2095
Cdd:TIGR00606  542 KDKMDKDEQIrkiksrhsdeltsLLGYFPNKKQLEDWLHSKSKEINQTRDRLaklnkeLASLEQNKNHINNELESKEEQL 621

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2096 DALHREKAHVEETLAEiQVSLTRKDQEMKELQGSLDSTLAQLAAFTKSMSSLQDDRDRVIDEAKKwerrfgdAIQTKEEe 2175
Cdd:TIGR00606  622 SSYEDKLFDVCGSQDE-ESDLERLKEEIEKSSKQRAMLAGATAVYSQFITQLTDENQSCCPVCQR-------VFQTEAE- 692

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2176 vrlKEENCIALKDQLRQMAIHMEELKITVSRLEHDKEIWESKA---QTELQHHQKAYDKLQEENKELTSQLEDARQLYHD 2252
Cdd:TIGR00606  693 ---LQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLApgrQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEE 769

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2253 SKNELTKLESELKSLKDQTTDLNnSLEKCKEHENNLEGIIKQQEADIQ-----------NCKFSCEQLETDLAASR-ELT 2320
Cdd:TIGR00606  770 QETLLGTIMPEEESAKVCLTDVT-IMERFQMELKDVERKIAQQAAKLQgsdldrtvqqvNQEKQEKQHELDTVVSKiELN 848

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2321 SRLHDEINAKEQKIISLLSG-KEEAIQL--------AVEELHQQHSKEIKELENLLSQEEEENVALEEENKRALEKTNQL 2391
Cdd:TIGR00606  849 RKLIQDQQEQIQHLKSKTNElKSEKLQIgtnlqrrqQFEEQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEEL 928

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2392 TEALEAIKKESFEQ----KAQLDSFVKSMSSLQDDRDRIVSDYRQLEERHLSAILEKdqlIQDAAAENNKLKEEMRGLRS 2467
Cdd:TIGR00606  929 ISSKETSNKKAQDKvndiKEKVKNIHGYMKDIENKIQDGKDDYLKQKETELNTVNAQ---LEECEKHQEKINEDMRLMRQ 1005

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2468 HMDDLNSENAKLDAELVQYRRDlNEVIAIKDSQQKQLLDAQLQQNKELRNECTKLEERLKGLEAEKQSLQMSSDALQKEK 2547
Cdd:TIGR00606 1006 DIDTQKIQERWLQDNLTLRKRE-NELKEVEEELKQHLKEMGQMQVLQMKQEHQKLEENIDLIKRNHVLALGRQKGYEKEI 1084

                          810
                   ....*....|...
gi 1039751022 2548 QGLSKEIKNLQTQ 2560
Cdd:TIGR00606 1085 KHFKKELREPQFR 1097
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1778-1994 4.92e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 51.69  E-value: 4.92e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1778 TFSSHDDIKNYLQQLDQLKGRIAELEMEKQKDRELSQALENEKNALLTQISAKDSELKLLEEEVtkrttlnQQIQEELCR 1857
Cdd:COG4942     15 AAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQEL-------AALEAELAE 87

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1858 VTKLKETAEEEKDDLEERLMNQLAELNGSIGNYY-------QDVTDAQIK-------NEQLESEMRNLQRCVSELEEEKQ 1923
Cdd:COG4942     88 LEKEIAELRAELEAQKEELAELLRALYRLGRQPPlalllspEDFLDAVRRlqylkylAPARREQAEELRADLAELAALRA 167

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1039751022 1924 QLVKEKTKVESEIRKEYMEKIQGAQKGPANKSHAKELQELLREKQQEVKQLQKDCIRYLERISALEKTVKA 1994
Cdd:COG4942    168 ELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAA 238
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
2060-2531 5.08e-06

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 52.35  E-value: 5.08e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2060 ESIKSQIKQKDE-DLLRRLEQaeekHRKEKKNMQEKLDALHREKAHVEETLAEIQVSLTRKDQEMKELQgSLDSTLAQLA 2138
Cdd:PRK02224   190 DQLKAQIEEKEEkDLHERLNG----LESELAELDEEIERYEEQREQARETRDEADEVLEEHEERREELE-TLEAEIEDLR 264

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2139 AFTKSMSSLQDDRDRVIDEAKKWERRFGDAIQTKEEEVRLKEENCIALKDQLRQMAIHMEELKIT-----VSRLEHDKEI 2213
Cdd:PRK02224   265 ETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRleecrVAAQAHNEEA 344

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2214 wESKAQTELQHHQKAyDKLQEENKELTSQLEDARQLYHDSKNELTKLESELKSLK----DQTTDLNNS---LEKCKEHEN 2286
Cdd:PRK02224   345 -ESLREDADDLEERA-EELREEAAELESELEEAREAVEDRREEIEELEEEIEELRerfgDAPVDLGNAedfLEELREERD 422

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2287 NLEGIIKQQEADIQNCKFSCEQLETDLAASR-------------------------ELTSRLHD---EINAKEQKIISLL 2338
Cdd:PRK02224   423 ELREREAELEATLRTARERVEEAEALLEAGKcpecgqpvegsphvetieedrerveELEAELEDleeEVEEVEERLERAE 502

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2339 SGKEEAIQL--------AVEELHQQHSKEIKE----LENLLSQEEEENVALEEENKRALEKTNQLTEALEAIkKESFEQK 2406
Cdd:PRK02224   503 DLVEAEDRIerleerreDLEELIAERRETIEEkrerAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEV-AELNSKL 581

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2407 AQLDSFVKSMSSLQDDRDRIVSDYRQLEERH--LSAILEKDQLIQDAAAEnnkLKEEMRGLRSHMDDLNSENAKLD-AEL 2483
Cdd:PRK02224   582 AELKERIESLERIRTLLAAIADAEDEIERLRekREALAELNDERRERLAE---KRERKRELEAEFDEARIEEAREDkERA 658

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1039751022 2484 VQYRRDLNEVIAIKDSQQKQLLDA------QLQQNKELRNECTKLEERLKGLEA 2531
Cdd:PRK02224   659 EEYLEQVEEKLDELREERDDLQAEigavenELEELEELRERREALENRVEALEA 712
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1278-1928 5.42e-06

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 52.33  E-value: 5.42e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1278 SIASELAKKSEEVLLLQDQINEQGLEIQNLKAASVEAQAHTELLKQELESSQLKVAGL-EHLKTLQPELDALHKHMGQKE 1356
Cdd:TIGR04523   44 TIKNELKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLnSDLSKINSEIKNDKEQKNKLE 123

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1357 EEVNYLYGQLSEKEQTLTTVQTEMVEQERLIKALHTQLEMQAKEHEERLKQAQVEICELKKKPTELeeeTNAKQQLqRKL 1436
Cdd:TIGR04523  124 VELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNI---DKIKNKL-LKL 199

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1437 QAALISRKEALKENKSLQEQLSSARDAVERLTKSLADVESQVSVQNQEKDAVLGKLTILQEERDKLIAEMDRFLLEnqsl 1516
Cdd:TIGR04523  200 ELLLSNLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKE---- 275

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1517 sgsCESLKLALGGLTEDKEKLMEELESVRSSKMaestewQEKHKELQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQE 1596
Cdd:TIGR04523  276 ---LEQNNKKIKELEKQLNQLKSEISDLNNQKE------QDWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQ 346

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1597 LYAKLRSTESDKREREKQLQDaeqemeemkekmrkfaksKQQKILELEEENDRLRaeaqpvggtgESMEALLSSNSSLKE 1676
Cdd:TIGR04523  347 LKKELTNSESENSEKQRELEE------------------KQNEIEKLKKENQSYK----------QEIKNLESQINDLES 398

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1677 ELEKITLEHKTLSKEFEALMAEKDALSEETRNLKLQVEAQvlKQASLEATEKSDEPKDVIEEVTQAVVGKSQERDALSDS 1756
Cdd:TIGR04523  399 KIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKN--NSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRS 476

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1757 AKLEDSEailmgdgAKPGVSETFSSHDDIKNYLQQLDQLKGRIAELEMEKQKDRELSQALENEKNALLTQISAKDSELKL 1836
Cdd:TIGR04523  477 INKIKQN-------LEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNK 549

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1837 LEEEVTKrTTLNQQIQEELCRVTKLKETAEEEKDDLEER-------------LMNQLAELNGSIGNYYQDVTDAQIKNEQ 1903
Cdd:TIGR04523  550 DDFELKK-ENLEKEIDEKNKEIEELKQTQKSLKKKQEEKqelidqkekekkdLIKEIEEKEKKISSLEKELEKAKKENEK 628

                          650       660
                   ....*....|....*....|....*
gi 1039751022 1904 LESEMRNLQRCVSELEEEKQQLVKE 1928
Cdd:TIGR04523  629 LSSIIKNIKSKKNKLKQEVKQIKET 653
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 85-335 7.67e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 51.30  E-value: 7.67e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022   85 AALPPEAQAEELSKHNKSSTEEEMEIEKIKHELQEKEKLISSLQAQLDQSEQasQLDKSSAEMEDfvlMKQQLQEKEELI 164
Cdd:COG4942     11 LALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALER--RIAALARRIRA---LEQELAALEAEL 85

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  165 STLQTQLSQTQAEQAAQLSSMQQVVRekdarfeTQVRLHEDELLQLVTQSDVETEMQQKLRVMQRKLEEHEEallgRAQV 244
Cdd:COG4942     86 AELEKEIAELRAELEAQKEELAELLR-------ALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARRE----QAEE 154

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  245 VDLLQKELTSAEQRNQVLSQQLQLLEAEHNTLKNTMETERQESKTLMEKVELEVAERKLSFHNLQEEMHQLQGQLERAGQ 324
Cdd:COG4942    155 LRADLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEA 234

                          250
                   ....*....|.
gi 1039751022  325 AQADLETQYSA 335
Cdd:COG4942    235 EAAAAAERTPA 245
PTZ00121 PTZ00121
MAEBL; Provisional
 676-1191 8.47e-06

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 52.07  E-value: 8.47e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  676 EKVKEISSLTQLSEEVKESAEEARSTLAAVTEERDQLLYQVKELDVLAELRARVQELEsslaEAEKQRGLDyESQRAQHN 755
Cdd:PTZ00121  1227 EAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELK----KAEEKKKAD-EAKKAEEK 1301

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  756 LLTEQIHSLSIEAKSKD---VKIEALQRELDGVQLQFCEQGTQMKTLQSQLEAKEREVREGTERlrdisQEMEGLSQALS 832
Cdd:PTZ00121  1302 KKADEAKKKAEEAKKADeakKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEK-----AEAAEKKKEEA 1376

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  833 QKELEIAKMDQlllEKQKDVETLQQTIQEKDQQVTELSFSMTEKmvQLNEEKFSLGVEIKT---LKEQLNLLSRTEEATK 909
Cdd:PTZ00121  1377 KKKADAAKKKA---EEKKKADEAKKKAEEDKKKADELKKAAAAK--KKADEAKKKAEEKKKadeAKKKAEEAKKADEAKK 1451

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  910 EQVEESGAGSSLKLGHDESGQEGLQQELELLRKESEQRKRKLQAalinrKELLQKVSQLEEELAKVREDSRKEIPFGENE 989
Cdd:PTZ00121  1452 KAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEA-----KKKADEAKKAAEAKKKADEAKKAEEAKKADE 1526

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  990 RRKLEEDRENRDDPEEWGTSKWREVEASlkqtiseKEVELEGIRRDLKEKTAAEEELQAVVQRMTRDLQSKTKQIDLLQE 1069
Cdd:PTZ00121  1527 AKKAEEAKKADEAKKAEEKKKADELKKA-------EELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMK 1599

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1070 EVTENQatiqklvtgTMDAGNGGSAAPVKETAASSPPGAggEEHWKPELEGRILDLEKDKTQLQKKLQEALIARKAILKK 1149
Cdd:PTZ00121  1600 LYEEEK---------KMKAEEAKKAEEAKIKAEELKKAE--EEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAK 1668

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|..
gi 1039751022 1150 AQEKEKQLKEELREQKDAYHHLQGQFHEQNKEKENiADQLRQ 1191
Cdd:PTZ00121  1669 KAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKK-AEELKK 1709
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2072-2280 8.59e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 50.92  E-value: 8.59e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2072 DLLRRLEQAEEKHRKEKKNMQEKLDALHREKAHVEETLAEIQVSLTRKDQEMKELQGSLDSTLAQLAAFTKSMSSLQDDR 2151
Cdd:COG4942     20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAEL 99

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2152 D-------RVIDEAKKWERRFGDAIQTKEEEVRLKEENCIALKDQLRQMAIHMEELKITVSRLEHDKEiwesKAQTELQH 2224
Cdd:COG4942    100 EaqkeelaELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRA----ELEAERAE 175

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1039751022 2225 HQKAYDKLQEENKELTSQLEDARQLYHDSKNELTKLESELKSLKDQTTDLNNSLEK 2280
Cdd:COG4942    176 LEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIAR 231
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1455-2001 1.37e-05

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 51.19  E-value: 1.37e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1455 EQLSSARDAVERLTK----SLADVESQVSvQNQEKDAVlGKLTILQEERDKLIAEMDRFLLENQSLSGSCESLKLALGGL 1530
Cdd:PRK02224   169 ERASDARLGVERVLSdqrgSLDQLKAQIE-EKEEKDLH-ERLNGLESELAELDEEIERYEEQREQARETRDEADEVLEEH 246

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1531 TEDKEKL------MEELESVRSSKMAESTEWQEKHKELQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQELYAKLRST 1604
Cdd:PRK02224   247 EERREELetleaeIEDLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEEL 326

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1605 ESDKREREKQLQDAEQEmeemkekmrkfAKSKQQKILELEEENDRLRAEAQPVGGTGESMEALLSSNSSLKEELEKitlE 1684
Cdd:PRK02224   327 RDRLEECRVAAQAHNEE-----------AESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEE---E 392

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1685 HKTLSKEFEALMAEKDALSEETRNLKLQVEAQVLKQASLEATEKSDEpkDVIEEVTQAV-----------VGKSQERDAL 1753
Cdd:PRK02224   393 IEELRERFGDAPVDLGNAEDFLEELREERDELREREAELEATLRTAR--ERVEEAEALLeagkcpecgqpVEGSPHVETI 470

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1754 SDS-AKLEDSEAILmgdgakpgvSETFSSHDDIKNYLQQLDQLKGRIAELEMEKQKdRELSQALENEKNALLTQISAKDS 1832
Cdd:PRK02224   471 EEDrERVEELEAEL---------EDLEEEVEEVEERLERAEDLVEAEDRIERLEER-REDLEELIAERRETIEEKRERAE 540

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1833 EL-----KLLEEEVTKR---TTLNQQIQEELCRVTKLKETAEEEKDDLEErlMNQLAELNGSIGNYYQDVTDAQIKNEQL 1904
Cdd:PRK02224   541 ELreraaELEAEAEEKReaaAEAEEEAEEAREEVAELNSKLAELKERIES--LERIRTLLAAIADAEDEIERLREKREAL 618

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1905 esemrnlqrcvSELEEEKQQLVKEKTKVESEIRKEYME-KIQGAQKGPAN-KSHAKELQELLREKQQEVKQLQKDC---- 1978
Cdd:PRK02224   619 -----------AELNDERRERLAEKRERKRELEAEFDEaRIEEAREDKERaEEYLEQVEEKLDELREERDDLQAEIgave 687

                          570       580
                   ....*....|....*....|....*....
gi 1039751022 1979 --IRYLE----RISALEKTVKALEFVHTE 2001
Cdd:PRK02224   688 neLEELEelreRREALENRVEALEALYDE 716
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
645-1081 1.37e-05

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 51.22  E-value: 1.37e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  645 HQGELERLKTQVLELETSLHTAEETYK---RNLSEKVKEISSLTQLSEEVKESAEEAR--STLAAVTEERDQLLYQVKEL 719
Cdd:PRK03918   236 LKEEIEELEKELESLEGSKRKLEEKIReleERIEELKKEIEELEEKVKELKELKEKAEeyIKLSEFYEEYLDELREIEKR 315

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  720 -----DVLAELRARVQELESSLAEAEKQRGLDYESQRAQHNLltEQIHSLSIEAKSKDVKIEALQRELDGVQLQFCEQgt 794
Cdd:PRK03918   316 lsrleEEINGIEERIKELEEKEERLEELKKKLKELEKRLEEL--EERHELYEEAKAKKEELERLKKRLTGLTPEKLEK-- 391

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  795 QMKTLQSQLEAKEREVREGTERLRDISQEMEGLSQALSQ------------KELEIAKMDQLLLEKQKDVETLQQTIQEK 862
Cdd:PRK03918   392 ELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEElkkakgkcpvcgRELTEEHRKELLEEYTAELKRIEKELKEI 471

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  863 DQQVTELSFSMTEKMVQLNEEK-----FSLGVEIKTLKEQLNLLSRTEEATKEQVEESGAGSSLKLGHDESGQEGLQQEL 937
Cdd:PRK03918   472 EEKERKLRKELRELEKVLKKESeliklKELAEQLKELEEKLKKYNLEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKL 551

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  938 ELLRKESEQRKRKLQAALINRKELLQK--------VSQLEEELAKVREDSRKEIPFGENERRKleEDRENRDDPEEWGTS 1009
Cdd:PRK03918   552 EELKKKLAELEKKLDELEEELAELLKEleelgfesVEELEERLKELEPFYNEYLELKDAEKEL--EREEKELKKLEEELD 629

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1039751022 1010 KWREVEASLKQTISEKEVELEGIRRDLKEKTaaEEELQAVVQRMTRDLQSKTKQIDLLQEEVTENQATIQKL 1081
Cdd:PRK03918   630 KAFEELAETEKRLEELRKELEELEKKYSEEE--YEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKL 699
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
722-994 1.42e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 51.07  E-value: 1.42e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  722 LAELRARVQELESSLAEAEKQRgldyESQRAQHNLLTEQIHSLS--IEAKSKDVKIEALQRELDGV--QLQFCEQG-TQM 796
Cdd:COG4913    612 LAALEAELAELEEELAEAEERL----EALEAELDALQERREALQrlAEYSWDEIDVASAEREIAELeaELERLDASsDDL 687

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  797 KTLQSQLEAKEREVREGTERLRDISQEMEGLSQALSQKELEIAKMDQLLLEKQKDVETLQQtiQEKDQQVTELSFSMTEK 876
Cdd:COG4913    688 AALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELR--ALLEERFAAALGDAVER 765

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  877 MVQLNeekfsLGVEIKTLKEQLNLLSRTEEATKEQVEESGAGSSLKLGHDESGQEGLQQELELLRKES----EQR-KRKL 951
Cdd:COG4913    766 ELREN-----LEERIDALRARLNRAEEELERAMRAFNREWPAETADLDADLESLPEYLALLDRLEEDGlpeyEERfKELL 840

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*....
gi 1039751022  952 QAALINRKELLQkvSQLEEELAKVRE------DSRKEIPFGENERRKLE 994
Cdd:COG4913    841 NENSIEFVADLL--SKLRRAIREIKEridplnDSLKRIPFGPGRYLRLE 887
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2738-3016 1.75e-05

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 50.71  E-value: 1.75e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2738 ENVLSRLEKLNQQLTSKDEQLLHLSSELESSHNQVQSISKAMTSLQNERDRLWSELEKFRKSEEGKQRaaapsaasspaE 2817
Cdd:COG1196    235 RELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQ-----------D 303

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2818 VQSLKKAMSSLQNDRDRLLKELKNLQQQYLQMSQEMTELRPLKAQLQESQDQTKALQVMEEELRQENLSWQHELRQLRME 2897
Cdd:COG1196    304 IARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEE 383

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2898 KNSWELHERRMKEQFLMAISDKDQQLGHLQSLLRELRSSSQAQILSTQYQRQASPETSASLDGSQKLVYETELLRTQLND 2977
Cdd:COG1196    384 LAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLE 463

                          250       260       270
                   ....*....|....*....|....*....|....*....
gi 1039751022 2978 SLKEIHQKELRIQQLNSKFSQLLEEKNVLSTQLSDASQS 3016
Cdd:COG1196    464 LLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEAD 502
46 PHA02562
endonuclease subunit; Provisional
 1785-1943 2.00e-05

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 50.40  E-value: 2.00e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1785 IKNYLQQLDQLKGRIAELEMEKQKDRELSQALENEKNALLTQISAKDSELKLLEEEVTKRTTLnQQIQEELCRVTKLKE- 1863
Cdd:PHA02562   229 AKTIKAEIEELTDELLNLVMDIEDPSAALNKLNTAAAKIKSKIEQFQKVIKMYEKGGVCPTCT-QQISEGPDRITKIKDk 307

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1864 --------TAEEEKDDLEERLMNQLA-------ELNGSIGNYYQDVTDAQIKNEQLESEMRNLQRCVSELEEEKQQLVKE 1928
Cdd:PHA02562   308 lkelqhslEKLDTAIDELEEIMDEFNeqskkllELKNKISTNKQSLITLVDKAKKVKAAIEELQAEFVDNAEELAKLQDE 387

                          170
                   ....*....|....*
gi 1039751022 1929 KTKVESEIRKEYMEK 1943
Cdd:PHA02562   388 LDKIVKTKSELVKEK 402
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 2196-2715 2.12e-05

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 50.50  E-value: 2.12e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2196 HMEELKITVSRLEHD----KEIWESK----------AQTELQHHQKAYDKLQEENKELTSQLEDARQLYHDSKNELTKLE 2261
Cdd:pfam15921  318 QLSDLESTVSQLRSElreaKRMYEDKieelekqlvlANSELTEARTERDQFSQESGNLDDQLQKLLADLHKREKELSLEK 397

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2262 SELKSLKDQTTDLNNSLEKCKEHENNLEGIIKQQEADIQNCKFSCE-QLETDLAAsreltsrlhdeinakeqkiislLSG 2340
Cdd:pfam15921  398 EQNKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSECQgQMERQMAA----------------------IQG 455

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2341 KEEAIQlAVEELHQQHSKEIKELENLLSQEEEENVALEEENKRALEKTNQLTE---ALEAIKKESFEQKAQLDSFVKSMS 2417
Cdd:pfam15921  456 KNESLE-KVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEkerAIEATNAEITKLRSRVDLKLQELQ 534

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2418 SLQDDRDRIVSDYRQLEERHLSaILEKDQLIQDAAAENNKLKEEMRGLRSHMDDLNSENAKLDAELVQYRRDLNEVIAIK 2497
Cdd:pfam15921  535 HLKNEGDHLRNVQTECEALKLQ-MAEKDKVIEILRQQIENMTQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQEFKILK 613

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2498 DSQQKQLldaqlqqnKELRNECTKLE-ERLKGLEAEKQSLQMSSDaLQKEKQGLSKEIKNLQTQLTALQE---------- 2566
Cdd:pfam15921  614 DKKDAKI--------RELEARVSDLElEKVKLVNAGSERLRAVKD-IKQERDQLLNEVKTSRNELNSLSEdyevlkrnfr 684

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2567 ------EGTLGVYHAQLKAKEEELQRLNMALSSSQKRTADLEEELVCVQKEATRKVSEIeDQLKKELKHLHHDAGIMRNE 2640
Cdd:pfam15921  685 nkseemETTTNKLKMQLKSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQI-DALQSKIQFLEEAMTNANKE 763

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1039751022 2641 TETAEERVAELARDLVEMEQKLLTVTKENKDLMAQIQAFGRSMSSLQDSRDHATEELGDLKKKYDASLKELAQLK 2715
Cdd:pfam15921  764 KHFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANMEVALDKASLQFAECQDIIQRQEQESVRLK 838
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1279-2021 2.14e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 50.45  E-value: 2.14e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1279 IASELAKKSEEVLLLQDQINEQGLEIQNLKAASVEAQAHTELLKQELESSQlkvaglEHLKTLQPELDALHKHMGQKEEE 1358
Cdd:TIGR02169  292 VKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELE------REIEEERKRRDKLTEEYAELKEE 365

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1359 VNYLYGQLSEKEQTLTTVQTEMveqerliKALHTQLEMQAKEHEERLKQAQVEICELKKKPTELEEETNAKQQLQRKLqA 1438
Cdd:TIGR02169  366 LEDLRAELEEVDKEFAETRDEL-------KDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKI-N 437

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1439 ALISRKEALKEN--------KSLQEQLSSARDAVERLTKSLADVESQVSVQNQEKDAVLGKLTILQEERDKLIAEMDRFL 1510
Cdd:TIGR02169  438 ELEEEKEDKALEikkqewklEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLK 517

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1511 LENQSLSGSCESL-----------KLALGG-----LTEDKEKLMEELESVRSSKMAEST-----EWQEKHKELQKEYEVL 1569
Cdd:TIGR02169  518 ASIQGVHGTVAQLgsvgeryataiEVAAGNrlnnvVVEDDAVAKEAIELLKRRKAGRATflplnKMRDERRDLSILSEDG 597

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1570 L-----------QSYENVSNEAERIQHVVESVrQEKQELYAKLRSTESDKREREKqlQDAEQEMEEMKEKMRKFAKSKQQ 1638
Cdd:TIGR02169  598 VigfavdlvefdPKYEPAFKYVFGDTLVVEDI-EAARRLMGKYRMVTLEGELFEK--SGAMTGGSRAPRGGILFSRSEPA 674

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1639 KILELEEENDRLRAEAQPVGGTGESMEALLSSNSSLKEELEKitlEHKTLSKEFEALMAEKDALSEETRNLKLQveaqvL 1718
Cdd:TIGR02169  675 ELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASR---KIGEIEKEIEQLEQEEEKLKERLEELEED-----L 746

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1719 KQASLEATEKSDEPKDVIEEVTQAVVGKSQERDALSDsakLEDSEAilmgdgakpgvsetfsshddiknyLQQLDQLKGR 1798
Cdd:TIGR02169  747 SSLEQEIENVKSELKELEARIEELEEDLHKLEEALND---LEARLS------------------------HSRIPEIQAE 799

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1799 IAELEMEKQKDRELSQALENEKNALltqisakDSELKLLEEEvtkrttlnqqIQEELCRVTKLKETAEEEKDDLEerlmn 1878
Cdd:TIGR02169  800 LSKLEEEVSRIEARLREIEQKLNRL-------TLEKEYLEKE----------IQELQEQRIDLKEQIKSIEKEIE----- 857

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1879 qlaELNGSIGNYYQDVTDAQIKNEQLESEMRNLQRCVSELEEEKQQLVKEKTKVESEIRKEYMEKIQGAQKGPANKSHAK 1958
Cdd:TIGR02169  858 ---NLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELS 934

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1039751022 1959 ELQELLREKQQEV------KQLQKDCIRYLERISALEKTVKALEFVHTESQKDLDVTKGNLAQAVEHRK 2021
Cdd:TIGR02169  935 EIEDPKGEDEEIPeeelslEDVQAELQRVEEEIRALEPVNMLAIQEYEEVLKRLDELKEKRAKLEEERK 1003
PTZ00121 PTZ00121
MAEBL; Provisional
 1690-2534 2.24e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 50.52  E-value: 2.24e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1690 KEFEALMAEKDALSEETRN-LKLQVEAQVLKQASLEATEKSDEPKDVIEEVTQAV-VGKSQERDALSDSAKLEDSEAILM 1767
Cdd:PTZ00121  1077 KDFDFDAKEDNRADEATEEaFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEeARKAEDARKAEEARKAEDAKRVEI 1156

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1768 GDGAKPGVSETFSSHDDiknylqqlDQLKGRIAELEMEKQKDRELSQALENEKnallTQISAKDSELKLLEEevtKRTTL 1847
Cdd:PTZ00121  1157 ARKAEDARKAEEARKAE--------DAKKAEAARKAEEVRKAEELRKAEDARK----AEAARKAEEERKAEE---ARKAE 1221

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1848 NQQIQEELCRVTKLKETAEEEKDDLEERLMNQLAELNGSIGNYYQDvTDAQIKNEQlesemrnlQRCVSELEEekqqlVK 1927
Cdd:PTZ00121  1222 DAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFAR-RQAAIKAEE--------ARKADELKK-----AE 1287

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1928 EKTKVESEIRKEYMEKIQGAQKGPANKSHAKELQELLREKQQEVKQLQKDCirylerisalEKTVKALEfvhtesqkdld 2007
Cdd:PTZ00121  1288 EKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKA----------EEAKKAAE----------- 1346

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2008 vtkgnLAQAVEHRKKAQAELSSFKILLDDTQSEAARVLADNLKLKKELQSNKESIKSQIKQ--KDEDLLRRLEQAEEKHR 2085
Cdd:PTZ00121  1347 -----AAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEdkKKADELKKAAAAKKKAD 1421

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2086 KEKKNMQEKLDALHREKAHVEETLAEiqvSLTRKDQEMKELQGSLDSTlaqlaaftksmsslqdDRDRVIDEAKK--WER 2163
Cdd:PTZ00121  1422 EAKKKAEEKKKADEAKKKAEEAKKAD---EAKKKAEEAKKAEEAKKKA----------------EEAKKADEAKKkaEEA 1482

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2164 RFGDAIQTKEEEVRLKEENcialkdqlrqmAIHMEELKITVSRLEHDKEIWESKAQTELQHHQKAYDKLQEENKELTSQL 2243
Cdd:PTZ00121  1483 KKADEAKKKAEEAKKKADE-----------AKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADEL 1551

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2244 EDARQLyhDSKNELTKLESELKSLKDQTTDLNNSLEKCKEHENNLEGIIKQQEadiQNCKFSCEQLEtdlaasreltsrl 2323
Cdd:PTZ00121  1552 KKAEEL--KKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYE---EEKKMKAEEAK------------- 1613

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2324 hdeiNAKEQKIISLLSGKEEAIQLAVEELHQQHSKEIKELENLLSQEEEENVALEEENKRALEKTNQlteALEAIKKESF 2403
Cdd:PTZ00121  1614 ----KAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKK---AEEAKKAEED 1686

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2404 EQKAQldsfvksmsslqddrdriVSDYRQLEERHLSAILEKDQLIQDAAAENNKLKEEMRGLRSHMDDLNSENAKLDAEL 2483
Cdd:PTZ00121  1687 EKKAA------------------EALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEE 1748

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1039751022 2484 VQYRRDLNEVIAIKDSQQKQLLDAQLQQNKELRNECTKLEERLKGLEAEKQ 2534
Cdd:PTZ00121  1749 AKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKK 1799
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 2216-2871 2.49e-05

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 50.02  E-value: 2.49e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2216 SKAQTELQHHQKAYDKLQEENKELTSQLEDARQLYHDSKNELTKLESELKSLKDQTTDLNNSLEKCKEHENNLEGIIKQQ 2295
Cdd:TIGR04523   29 NKQDTEEKQLEKKLKTIKNELKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDLSKI 108

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2296 EADIQNCKfsceqletdlaasreltsrlhDEINAKEQKIISLLSGKEEaiqlaVEELHQQHSKEIKELENLLsqeeeenv 2375
Cdd:TIGR04523  109 NSEIKNDK---------------------EQKNKLEVELNKLEKQKKE-----NKKNIDKFLTEIKKKEKEL-------- 154

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2376 aleeenkralektNQLTEALEAIKKESFEQKAQLDSFVKSMSSLQDDRDRIVSDYRQLEERhLSAILEKDQLIQDAAAEN 2455
Cdd:TIGR04523  155 -------------EKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKLELL-LSNLKKKIQKNKSLESQI 220

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2456 NKLKEEMRGLRSHMDDLNSENAKLDAELVQYRRDLNEVIAIKDSQQKQLLDAQlqqnkelrNECTKLEERLKGLEAEKQS 2535
Cdd:TIGR04523  221 SELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQ--------KELEQNNKKIKELEKQLNQ 292

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2536 LQMSSDALQKEKQ-----GLSKEIKNLQTQLTALQeegtlgvyhAQLKAKEEELQRLNMALSSSQKRTADLEEELVCVQK 2610
Cdd:TIGR04523  293 LKSEISDLNNQKEqdwnkELKSELKNQEKKLEEIQ---------NQISQNNKIISQLNEQISQLKKELTNSESENSEKQR 363

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2611 EATRKVSEIE------DQLKKELKHLHHDAGIMRNETETAEE---------RVAELARDLVEMEQKLLTVT-----KENK 2670
Cdd:TIGR04523  364 ELEEKQNEIEklkkenQSYKQEIKNLESQINDLESKIQNQEKlnqqkdeqiKKLQQEKELLEKEIERLKETiiknnSEIK 443

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2671 DLMAQIQAFGRSMSSLQDSRDHATEELGDLKKKYDASLKELAQLKewQDSSREGDVLSQAAFPLSTSENVLSRLEKLNQQ 2750
Cdd:TIGR04523  444 DLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQ--KELKSKEKELKKLNEEKKELEEKVKDLTKKISS 521

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2751 LTSKDEQLLHLSSELESSHNQVQSISKAMTS------LQNERDRLWSELEKFR---KSEEGKQRAAAPSAASSPAEVQSL 2821
Cdd:TIGR04523  522 LKEKIEKLESEKKEKESKISDLEDELNKDDFelkkenLEKEIDEKNKEIEELKqtqKSLKKKQEEKQELIDQKEKEKKDL 601

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2822 KKAMSSLQNDRDRLLKELKNLQQQYLQMSQEMTELRPLKAQLQESQDQTK 2871
Cdd:TIGR04523  602 IKEIEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIK 651
PTZ00121 PTZ00121
MAEBL; Provisional
 679-1489 2.70e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 50.52  E-value: 2.70e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  679 KEISSLTQLSEEVKESAEEARSTLAA-VTEERDQLLYQVKELDVLAELRARVQELESSLAEAEKQRgldyESQRAQHNLL 757
Cdd:PTZ00121  1084 KEDNRADEATEEAFGKAEEAKKTETGkAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAE----DAKRVEIARK 1159

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  758 TEQIHSLSIEAKSKDV-KIEALQReldGVQLQFCEQGTQMKTLQSQLEAKEREVREGTERLRDISQEmeglSQALSQKEL 836
Cdd:PTZ00121  1160 AEDARKAEEARKAEDAkKAEAARK---AEEVRKAEELRKAEDARKAEAARKAEEERKAEEARKAEDA----KKAEAVKKA 1232

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  837 EIAKMDQllLEKQKDVETLQQTIQEKDQQVTELSFSMTEKMVQLNEEKFSLGVEIKTLKEQLNLLSRTEEATKEQVEESG 916
Cdd:PTZ00121  1233 EEAKKDA--EEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKK 1310

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  917 AGSSLKLGHDESGQEGLQQELELLRKESEQRKRKLQAALINRKELLQKVSQLEEELAKVREDSRKEIPFGENERRKLEED 996
Cdd:PTZ00121  1311 AEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEK 1390

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  997 RENRDDPEEWGTSKWREVEASLKQTISEKEVELegiRRDLKEKTAAEEELQAVVQRMTRDLQSKTKQIDLLQEEVTENQA 1076
Cdd:PTZ00121  1391 KKADEAKKKAEEDKKKADELKKAAAAKKKADEA---KKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAE 1467

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1077 TIQKLVTGTMDAGNGGSAAPVKETAassppgaggEEHWKPELEGRILDLEKDKTQLQKKLQEALIARKAilKKAQEKEKq 1156
Cdd:PTZ00121  1468 EAKKADEAKKKAEEAKKADEAKKKA---------EEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEA--KKAEEAKK- 1535

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1157 lKEELREQKDAYHHLQGQFHEQNKEkeniADQLRQLQCQARESIDRQLPGTGQQEpgppapslegisLEDTEPASESDLH 1236
Cdd:PTZ00121  1536 -ADEAKKAEEKKKADELKKAEELKK----AEEKKKAEEAKKAEEDKNMALRKAEE------------AKKAEEARIEEVM 1598

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1237 AAQPSPPGETAALQATVSVAQIQAQLKEMEVEKEELELKVSSIASELAKKSEEVlllQDQINEQGLEIQNLKAASVEAQA 1316
Cdd:PTZ00121  1599 KLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEEL---KKAEEENKIKAAEEAKKAEEDKK 1675

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1317 HTELLKQELESSQLKVaglEHLKTLQPEldalhkhmGQKEEEVnylygQLSEKEQTLTTVQTEMVEQERLIKAlhTQLEM 1396
Cdd:PTZ00121  1676 KAEEAKKAEEDEKKAA---EALKKEAEE--------AKKAEEL-----KKKEAEEKKKAEELKKAEEENKIKA--EEAKK 1737

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1397 QAKEHEERLKQAQVEICElKKKPTELEEETNAKQQLQRKLQAALIsrKEALKENKSLQeqlssaRDAVERLTKSLADVES 1476
Cdd:PTZ00121  1738 EAEEDKKKAEEAKKDEEE-KKKIAHLKKEEEKKAEEIRKEKEAVI--EEELDEEDEKR------RMEVDKKIKDIFDNFA 1808

                          810
                   ....*....|...
gi 1039751022 1477 QVSVQNQEKDAVL 1489
Cdd:PTZ00121  1809 NIIEGGKEGNLVI 1821
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
118-327 3.22e-05

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 49.63  E-value: 3.22e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  118 QEKEKLISSLQAQLDQSEQasQLDKSSAEMEDF------VLMKQQLQEKEELISTLQTQLSQTQAEQAAQLSSMQQVVRE 191
Cdd:COG3206    171 EEARKALEFLEEQLPELRK--ELEEAEAALEEFrqknglVDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQ 248

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  192 KDARFETQVRLHEDELLQLVTQSDVETEmQQKLRVMQRKLEEHEEALLGRAQVVDLLQKELTSAEQRNQVLSQQLQLLEA 271
Cdd:COG3206    249 LGSGPDALPELLQSPVIQQLRAQLAELE-AELAELSARYTPNHPDVIALRAQIAALRAQLQQEAQRILASLEAELEALQA 327

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1039751022  272 EHNTLKNTMETERQESKTLMEK-VELEVAERKLSfhNLQEEMHQLQGQLERAGQAQA 327
Cdd:COG3206    328 REASLQAQLAQLEARLAELPELeAELRRLEREVE--VARELYESLLQRLEEARLAEA 382
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 115-896 3.34e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 50.07  E-value: 3.34e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  115 HELQEKEKLISSLQAQLDQSEQasQLDKSSAEMEDFVlmkQQLQEKEELISTLQTQLSQTQAEQAAQLSSMQQVVREKDA 194
Cdd:TIGR02169  230 KEKEALERQKEAIERQLASLEE--ELEKLTEEISELE---KRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIA 304

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  195 RFETQVRLHEDELLQLVTQsdvETEMQQKLRVMQRKLEEHEEALLGRAQVVDLLQKELTSAEQRNQVLSQQLQLLEAEHN 274
Cdd:TIGR02169  305 SLERSIAEKERELEDAEER---LAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFA 381

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  275 TLKNTMETERQE-SKTLMEKVELEVAERKL--SFHNLQEEMHQLQGQLERAGQAQADLEtqysalqqrhktemEEKTACI 351
Cdd:TIGR02169  382 ETRDELKDYREKlEKLKREINELKRELDRLqeELQRLSEELADLNAAIAGIEAKINELE--------------EEKEDKA 447

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  352 LSLQKNEQELQSACAALKEENSKLLQEKHDQaaesaqamRQLEDQLQQKSKEISQFVNKPNLQKNETASQTSLPDVNNEG 431
Cdd:TIGR02169  448 LEIKKQEWKLEQLAADLSKYEQELYDLKEEY--------DRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKAS 519

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  432 DQAVMeETVASLQKrvVELENEKGALLLSSGELEELKAENEKLSSRITLLEAQNRAGEAdgtvcevstagTTLLNRSDSS 511
Cdd:TIGR02169  520 IQGVH-GTVAQLGS--VGERYATAIEVAAGNRLNNVVVEDDAVAKEAIELLKRRKAGRA-----------TFLPLNKMRD 585

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  512 PEENGQAVLENTFSqkhkELSVLLVEMKEAQEEIAF-------LKSQLQGKRPEGDYEVLDRREVQLMESEGppSVTAGD 584
Cdd:TIGR02169  586 ERRDLSILSEDGVI----GFAVDLVEFDPKYEPAFKyvfgdtlVVEDIEAARRLMGKYRMVTLEGELFEKSG--AMTGGS 659

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  585 VlcAPSDESSGPAAEEEQAgmkdrhraseagplndagmELSSPKLDGVDKSLAVShvcqchQGELERLKTQVLELETSLH 664
Cdd:TIGR02169  660 R--APRGGILFSRSEPAEL-------------------QRLRERLEGLKRELSSL------QSELRRIENRLDELSQELS 712

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  665 TAEetykRNLSEKVKEISSLTQLSEEVKESAEEARSTLAAVTEERDQLLYQVKELD--------VLAELRARVQELESSL 736
Cdd:TIGR02169  713 DAS----RKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEarieeleeDLHKLEEALNDLEARL 788

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  737 AEAE-KQRGLDYESQRAQHNLLTEQIHSLSIEAKSKDVKIEALQRELDGVQLQFCEQGTQMKTLQSQLEAKEREVREGTE 815
Cdd:TIGR02169  789 SHSRiPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEE 868

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  816 RLRDISQEMEGLSQALSQKELEIAKMDQLLLEKQKDVETLQQTIQEKDQQVTELsfsmTEKMVQLNEEKFSLGVEIKTLK 895
Cdd:TIGR02169  869 ELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSEL----KAKLEALEEELSEIEDPKGEDE 944


                   .
gi 1039751022  896 E 896
Cdd:TIGR02169  945 E 945
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
2217-2846 3.55e-05

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 49.68  E-value: 3.55e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2217 KAQTELQHHQKAYDKLQEENKELTSQLEDARQLYHDSKNELTKLESELKSLKDQTTDLNNSLEKCKEHENNLE---GIIK 2293
Cdd:PRK03918   162 NAYKNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEelkEEIE 241

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2294 QQEADIQNCKFSCEQLETDLAASRELTSRLHDEINAKEQKIISLLSGKEEAIQ-LAVEELHQQHSKEIKELENLLSQEEE 2372
Cdd:PRK03918   242 ELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKEKAEEyIKLSEFYEEYLDELREIEKRLSRLEE 321

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2373 ENVALeeenKRALEKTNQLTEALEAIKKESFEQKAQLDSFVKSMSSLQDDRdRIVSDYRQLEERhlsailEKDQLIQDAA 2452
Cdd:PRK03918   322 EINGI----EERIKELEEKEERLEELKKKLKELEKRLEELEERHELYEEAK-AKKEELERLKKR------LTGLTPEKLE 390

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2453 AENNKLKEEMRGLRSHMDDLNSENAKLDAELVQYRRDLNEVIAIK-----------DSQQKQLLDAQLQQNKELRNECTK 2521
Cdd:PRK03918   391 KELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKgkcpvcgreltEEHRKELLEEYTAELKRIEKELKE 470

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2522 LEERLKGLEAEKQSLQMssdALQKEKQGLSkeIKNLQTQLTALQEEgtLGVYHAQ-LKAKEEELQRLNMALSSSQKRTAD 2600
Cdd:PRK03918   471 IEEKERKLRKELRELEK---VLKKESELIK--LKELAEQLKELEEK--LKKYNLEeLEKKAEEYEKLKEKLIKLKGEIKS 543

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2601 LEEELVCVQ--KEATRKVSEIEDQLKKELKHLHHdagIMRNETETAEERVAELARDLVEMEQKLLTVtkenKDLMAQIQA 2678
Cdd:PRK03918   544 LKKELEKLEelKKKLAELEKKLDELEEELAELLK---ELEELGFESVEELEERLKELEPFYNEYLEL----KDAEKELER 616

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2679 FGRSMSSLQDSRDHATEELGDLKKKYDASLKELAQLKEWQDSSRegdvlsqaafplstsenvlsrLEKLNQQLTSKDEQL 2758
Cdd:PRK03918   617 EEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEEE---------------------YEELREEYLELSREL 675

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2759 LHLSSELESSHNQVQSISKAMTSLQNERDrlwsELEKFRKseegkqraaapsaasspaEVQSLKKAMSSLQNDRDRlLKE 2838
Cdd:PRK03918   676 AGLRAELEELEKRREEIKKTLEKLKEELE----EREKAKK------------------ELEKLEKALERVEELREK-VKK 732


                   ....*...
gi 1039751022 2839 LKNLQQQY 2846
Cdd:PRK03918   733 YKALLKER 740
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 13-483 3.58e-05

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 49.94  E-value: 3.58e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022   13 EDALHRLAEAEKLVVELKDIISQKDVQLQQKDEALQEEKKAAENKIKKIKLHAKAKIMSLNKHMEEIKTQGGAALPPEAQ 92
Cdd:COG1196    315 EERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRA 394

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022   93 AEELSKH---------NKSSTEEEMEIEKIKHELQEKEKLISSLQAQLDQSEQASQLDKSSAEMEDFVLMKQQLQEKEEL 163
Cdd:COG1196    395 AAELAAQleeleeaeeALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAAL 474

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  164 ISTLQTQLSQTQAEQAAQLSSMQQVVREKDARFETQVRLHEDELLQLVTQsdVETEMQQKLRVMQRKLEEHEEALLGRAQ 243
Cdd:COG1196    475 LEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAG--AVAVLIGVEAAYEAALEAALAAALQNIV 552

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  244 VVDLLQKE------------------LTSAEQRNQVLSQQLQLLEAEHNTLKNTMETERQESKTLMEKVELEVAERKLSF 305
Cdd:COG1196    553 VEDDEVAAaaieylkaakagratflpLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARL 632

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  306 HNLQEEMHQLQGQLERAGQAQADLETQYSALQQRHKTEMEEktacILSLQKNEQELQSACAALKEENSKLLQEKHDQAAE 385
Cdd:COG1196    633 EAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAA----LLEAEAELEELAERLAEEELELEEALLAEEEEERE 708

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  386 SAQAMRQLEDQLQQKSKEISQfVNKPNLQKNETASQTSLPDVNNEGDQAVMEETVASLQKRVVELENEKGAL----LLSS 461
Cdd:COG1196    709 LAEAEEERLEEELEEEALEEQ-LEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEALgpvnLLAI 787

                          490       500
                   ....*....|....*....|..
gi 1039751022  462 GELEELKAENEKLSSRITLLEA 483
Cdd:COG1196    788 EEYEELEERYDFLSEQREDLEE 809
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 1392-2208 4.19e-05

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 49.66  E-value: 4.19e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1392 TQLEMQAKEHEERLKQAQVEICELKKKPTELEEETNAKQQLQRKLQAALISRKEALKENKSLQEQL-------------- 1457
Cdd:TIGR00606  227 TSKEAQLESSREIVKSYENELDPLKNRLKEIEHNLSKIMKLDNEIKALKSRKKQMEKDNSELELKMekvfqgtdeqlndl 306

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1458 -----SSARDAVERLT---KSLADVESQVSVQNQEKDAVLGKLTILQEERDKLIAEMDRFLLENQSLSGSCESLKLALGG 1529
Cdd:TIGR00606  307 yhnhqRTVREKERELVdcqRELEKLNKERRLLNQEKTELLVEQGRLQLQADRHQEHIRARDSLIQSLATRLELDGFERGP 386

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1530 LTEDKEKLMEELESVRSSKMAES------------TEWQEKHKELQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQEL 1597
Cdd:TIGR00606  387 FSERQIKNFHTLVIERQEDEAKTaaqlcadlqskeRLKQEQADEIRDEKKGLGRTIELKKEILEKKQEELKFVIKELQQL 466

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1598 YAKLRSTESDKREREKQLQDAEQEME----EMKEKMRKFAKSKQQKILELEEENDRLRAEAQPVGGTGESMEALLSSNSS 1673
Cdd:TIGR00606  467 EGSSDRILELDQELRKAERELSKAEKnsltETLKKEVKSLQNEKADLDRKLRKLDQEMEQLNHHTTTRTQMEMLTKDKMD 546

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1674 LKEELEKITLEH--------------KTLSKEFEALMAEKDALSEETRNLKLQVEAQVLKQASLEATEKSDEPKDV---- 1735
Cdd:TIGR00606  547 KDEQIRKIKSRHsdeltsllgyfpnkKQLEDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSsyed 626

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1736 --------------IEEVTQAVVGKSQERDALSDSAKLEDS---EAILMGDGAKPGVSETFSSHDDIKNYLQQLdQLKGR 1798
Cdd:TIGR00606  627 klfdvcgsqdeesdLERLKEEIEKSSKQRAMLAGATAVYSQfitQLTDENQSCCPVCQRVFQTEAELQEFISDL-QSKLR 705

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1799 IAELEMEKQKdrELSQALENEKNALLTQISAKDSELKLLEEEVTKRTTLNQQIQEELCRVTKLKETAEEEKDDL--EERL 1876
Cdd:TIGR00606  706 LAPDKLKSTE--SELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTImpEEES 783

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1877 MNQLAELNGSIGNYYQDVTDAQIKNEQLESEMR--NLQRCVSELEEEKQQLVKEKTKVESEIR------KEYMEKIQGAQ 1948
Cdd:TIGR00606  784 AKVCLTDVTIMERFQMELKDVERKIAQQAAKLQgsDLDRTVQQVNQEKQEKQHELDTVVSKIElnrkliQDQQEQIQHLK 863

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1949 -KGPANKSHAKELQELLREKQQEVKQLQKDCIRYLERISALEKTVKALEFVHTESQKDLDVTKGNLAQAVEHRKKAQAEl 2027
Cdd:TIGR00606  864 sKTNELKSEKLQIGTNLQRRQQFEEQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEELISSKETSNKKAQDK- 942

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2028 ssfkilLDDTQSEAARVLADNLKLKKELQSNKESIKSQIKQKDEDLLRRLEQAEEKHRKEKKNMQEKLDALhrEKAHVEE 2107
Cdd:TIGR00606  943 ------VNDIKEKVKNIHGYMKDIENKIQDGKDDYLKQKETELNTVNAQLEECEKHQEKINEDMRLMRQDI--DTQKIQE 1014

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2108 TLAEIQVSLTRKDQEMKELQGSLDSTLAQLA-----AFTKSMSSLQDDRDRV-IDEAKKWERRFGDAIQTKEEEVRLKEE 2181
Cdd:TIGR00606 1015 RWLQDNLTLRKRENELKEVEEELKQHLKEMGqmqvlQMKQEHQKLEENIDLIkRNHVLALGRQKGYEKEIKHFKKELREP 1094

                          890       900
                   ....*....|....*....|....*..
gi 1039751022 2182 NCIALKDQLRQMAIHMEELKITVSRLE 2208
Cdd:TIGR00606 1095 QFRDAEEKYREMMIVMRTTELVNKDLD 1121
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2354-2567 4.36e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 48.61  E-value: 4.36e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2354 QQHSKEIKELENLLSQEEEENVALEEENKRALEKTNQLTEALEAIKKESFEQKAQLDSFVKSMSSLQDDRD--------R 2425
Cdd:COG4942     30 EQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEaqkeelaeL 109

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2426 IVSDYRQLEERHLSAILEKDQlIQDAAAENNKLKEEMRGLRSHMDDLNSENAKLdaelvqyrRDLNEVIAIKDSQQKQLL 2505
Cdd:COG4942    110 LRALYRLGRQPPLALLLSPED-FLDAVRRLQYLKYLAPARREQAEELRADLAEL--------AALRAELEAERAELEALL 180

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1039751022 2506 DAQLQQNKELRNECTKLEERLKGLEAEKQSLQMSSDALQKEKQGLSKEIKNLQTQLTALQEE 2567
Cdd:COG4942    181 AELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1775-2516 4.38e-05

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 49.35  E-value: 4.38e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1775 VSETFSSHDDIKNYLQQ-LDQLKGRIAELEMEKQK----DRELSQALENEKNALLTQISAKDSELKLLEEEVTKRTTLNQ 1849
Cdd:pfam15921   94 LNESNELHEKQKFYLRQsVIDLQTKLQEMQMERDAmadiRRRESQSQEDLRNQLQNTVHELEAAKCLKEDMLEDSNTQIE 173

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1850 QIQEELCRVTKLKETAEEEKDDLEERLMNQLAELNGSIGNYYQDVTDAQIKN-EQLESEMRNLQRCVSELEEEKQQLVKE 1928
Cdd:pfam15921  174 QLRKMMLSHEGVLQEIRSILVDFEEASGKKIYEHDSMSTMHFRSLGSAISKIlRELDTEISYLKGRIFPVEDQLEALKSE 253

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1929 ------------KTKVESEIRKEYMEKIQGAQKGPANKSHAKELQELLREKQQEVKQLQKdciRYLERISALEKTVKALE 1996
Cdd:pfam15921  254 sqnkielllqqhQDRIEQLISEHEVEITGLTEKASSARSQANSIQSQLEIIQEQARNQNS---MYMRQLSDLESTVSQLR 330

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1997 FVHTESQK----DLDVTKGNLAQAVEHRKKAQAELSSFKILLDDTQSEAARVLADNLKLKKELQSNKESIKsqiKQKDED 2072
Cdd:pfam15921  331 SELREAKRmyedKIEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLADLHKREKELSLEKEQNK---RLWDRD 407

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2073 LLRRLEQAEEKHRKEKKNMQekldaLHREKAHVEETLAEIQVSLtrkDQEMKELQGSlDSTLAQLAAFTKSMSSLQDDRD 2152
Cdd:pfam15921  408 TGNSITIDHLRRELDDRNME-----VQRLEALLKAMKSECQGQM---ERQMAAIQGK-NESLEKVSSLTAQLESTKEMLR 478

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2153 RVIDE--AKKW-----ERRFGD---AIQTKEEEVRLKEENCIALK-----------------DQLRQMAIHMEELKITVS 2205
Cdd:pfam15921  479 KVVEEltAKKMtlessERTVSDltaSLQEKERAIEATNAEITKLRsrvdlklqelqhlknegDHLRNVQTECEALKLQMA 558

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2206 RLEHDKEIWESKAQTELQ---HHQKAYDKLQEENKELTSQLEDARQLYHDSKNELTKLESELKSLKDQTTDLnnSLEKCK 2282
Cdd:pfam15921  559 EKDKVIEILRQQIENMTQlvgQHGRTAGAMQVEKAQLEKEINDRRLELQEFKILKDKKDAKIRELEARVSDL--ELEKVK 636

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2283 ehennLEGIIKQQEADIQNCKFSCEQLETDLAASRELTSRLHDEINAKEQKiislLSGKEEAIQLAVEELHQQHSKEIKE 2362
Cdd:pfam15921  637 -----LVNAGSERLRAVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRN----FRNKSEEMETTTNKLKMQLKSAQSE 707

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2363 LENLLSQEEEENVALEEENKRALEKTNQLTEaleaikkesfeQKAQLDSFVKSMSSLQDDRDRIVSDYRQLEErhlsail 2442
Cdd:pfam15921  708 LEQTRNTLKSMEGSDGHAMKVAMGMQKQITA-----------KRGQIDALQSKIQFLEEAMTNANKEKHFLKE------- 769

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1039751022 2443 EKDQLIQD---AAAENNKLKEEMRGLRSHMDDLNSENAKLDAELVQYRRDLNEVIAIKDSQQKQLLDAQLQQNKELR 2516
Cdd:pfam15921  770 EKNKLSQElstVATEKNKMAGELEVLRSQERRLKEKVANMEVALDKASLQFAECQDIIQRQEQESVRLKLQHTLDVK 846
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 2174-2923 4.57e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 49.30  E-value: 4.57e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2174 EEVRLKEENCIALKDQLRQmaiHMEELKITVSRLEHDKEIWESKAQTELQHHQKAYDKLQEENKELTSQLEDARQLYHDS 2253
Cdd:TIGR02169  180 EEVEENIERLDLIIDEKRQ---QLERLRREREKAERYQALLKEKREYEGYELLKEKEALERQKEAIERQLASLEEELEKL 256

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2254 KNELTKLESELKSLKDQTTDLNNSLEKCKEHE-NNLEGIIKQQEADIQNCKFSCEQLETDLAASRELTSRLHDEINAKEQ 2332
Cdd:TIGR02169  257 TEEISELEKRLEEIEQLLEELNKKIKDLGEEEqLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLA 336

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2333 KIISLlSGKEEAIQLAVEELhqqhSKEIKELENLLSQEEEENVALEEENKRALEKTNQLTEALEAIKKEsfeqkaqldsf 2412
Cdd:TIGR02169  337 EIEEL-EREIEEERKRRDKL----TEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKRE----------- 400

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2413 vksMSSLQDDRDRIVSDYRQLEERhlsaILEKDQLIQDAAAENNKLKEEMRGLRshmddlnsenakldAELVQYRRDLNE 2492
Cdd:TIGR02169  401 ---INELKRELDRLQEELQRLSEE----LADLNAAIAGIEAKINELEEEKEDKA--------------LEIKKQEWKLEQ 459

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2493 VIAIKDSQQKQLLDAQLQQNKeLRNECTKLEERLKGLEAEKQSL---QMSSDALQKEKQGLSKEIKNLQTQLTALQEEGT 2569
Cdd:TIGR02169  460 LAADLSKYEQELYDLKEEYDR-VEKELSKLQRELAEAEAQARASeerVRGGRAVEEVLKASIQGVHGTVAQLGSVGERYA 538

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2570 LGVYHA---QLKA----------------KEEELQRLN-MALSSSQKRTADLEEELVCVQKEATRKVSEIEDQLKKELKH 2629
Cdd:TIGR02169  539 TAIEVAagnRLNNvvveddavakeaiellKRRKAGRATfLPLNKMRDERRDLSILSEDGVIGFAVDLVEFDPKYEPAFKY 618

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2630 LHHDAGIMRNeTETAEE-----RVAELARDLVE----------MEQKLLTVTKENKD----LMAQIQAFGRSMSSLQDSR 2690
Cdd:TIGR02169  619 VFGDTLVVED-IEAARRlmgkyRMVTLEGELFEksgamtggsrAPRGGILFSRSEPAelqrLRERLEGLKRELSSLQSEL 697

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2691 DHATEELGDLKKKYDASLKELAQL-KEWQDSSREGDVLSQAAfplstsENVLSRLEKLNQQLTSKDEQLLHLSSELESSH 2769
Cdd:TIGR02169  698 RRIENRLDELSQELSDASRKIGEIeKEIEQLEQEEEKLKERL------EELEEDLSSLEQEIENVKSELKELEARIEELE 771

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2770 NQVQSISKAMTSLQNERDRlwselEKFRKSEEgKQRAAAPSAASSPAEVQSLKKAMSSLQNDRDRLLKELKNLQQQylqm 2849
Cdd:TIGR02169  772 EDLHKLEEALNDLEARLSH-----SRIPEIQA-ELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQ---- 841

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1039751022 2850 sqemteLRPLKAQLQESQDQTKALQVMEEELRQENLSWQHELRQLRMEKNSWELHERRMKEQfLMAISDKDQQL 2923
Cdd:TIGR02169  842 ------RIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQ-LRELERKIEEL 908
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
2441-2698 4.60e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 49.53  E-value: 4.60e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2441 ILEKDQLIQDAAAennkLKEEMRGLRSHMDDLNSENAKLDA--ELVQYRRDLNEVIAIKDSQQKQLLDAQLQQNKE---- 2514
Cdd:COG4913    217 MLEEPDTFEAADA----LVEHFDDLERAHEALEDAREQIELlePIRELAERYAAARERLAELEYLRAALRLWFAQRrlel 292

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2515 LRNECTKLEERLKGLEAEKQSLQMSSDALQKEKQGLSKEIKNLQTQ-LTALQEEgtlgvyhaqLKAKEEELQRLNMALSS 2593
Cdd:COG4913    293 LEAELEELRAELARLEAELERLEARLDALREELDELEAQIRGNGGDrLEQLERE---------IERLERELEERERRRAR 363

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2594 SQKRTADLEEELVCVQKEATRKVSEIEDQLkkelkhlhhdagimrnetETAEERVAELARDLVEMEQKLLTVTKENKDLM 2673
Cdd:COG4913    364 LEALLAALGLPLPASAEEFAALRAEAAALL------------------EALEEELEALEEALAEAEAALRDLRRELRELE 425

                          250       260
                   ....*....|....*....|....*....
gi 1039751022 2674 AQIQAFGRSMSS----LQDSRDHATEELG 2698
Cdd:COG4913    426 AEIASLERRKSNiparLLALRDALAEALG 454
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 1534-3037 5.12e-05

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 49.28  E-value: 5.12e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1534 KEKLMEELESVRSSKMAESTEWQEKHKELQKEYEV-------LLQSYENVSNEAERIQHVVESVRQEKQELYAKLRSTeS 1606
Cdd:TIGR01612  535 KAKLYKEIEAGLKESYELAKNWKKLIHEIKKELEEenedsihLEKEIKDLFDKYLEIDDEIIYINKLKLELKEKIKNI-S 613

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1607 DKREREKQLQDAEQEMEEMKEKMRKFAKSKQQKILELEEENDRL----RAEAQPVggTGESMEALLSSNSSLKEELEKIT 1682
Cdd:TIGR01612  614 DKNEYIKKAIDLKKIIENNNAYIDELAKISPYQVPEHLKNKDKIystiKSELSKI--YEDDIDALYNELSSIVKENAIDN 691

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1683 LEHKTlskEFEALMAEKDALSEETRNLklqvEAQVLKQASLEATEKSDEPKDVIEEVTQAVVGK-SQERDALsdsakLED 1761
Cdd:TIGR01612  692 TEDKA---KLDDLKSKIDKEYDKIQNM----ETATVELHLSNIENKKNELLDIIVEIKKHIHGEiNKDLNKI-----LED 759

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1762 seailmgdgAKPGVSETFSSHDDIKNYLQQLDQLKGRIAELE--------MEKQKDRELSQALENEKNALLTqISAKD-- 1831
Cdd:TIGR01612  760 ---------FKNKEKELSNKINDYAKEKDELNKYKSKISEIKnhyndqinIDNIKDEDAKQNYDKSKEYIKT-ISIKEde 829

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1832 -----SELKLLEEE----VTKRTTLNQQIQEELCR--------VTKLKETAEEEKDDLEERLMNQ----LAELNGSIGNY 1890
Cdd:TIGR01612  830 ifkiiNEMKFMKDDflnkVDKFINFENNCKEKIDSeheqfaelTNKIKAEISDDKLNDYEKKFNDskslINEINKSIEEE 909

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1891 YQDVTDAQIKNEQLE---------SEMRNLQRCVSELEEEKQQLVKEKTKVESEIRKEY----------MEKIQGAQKGP 1951
Cdd:TIGR01612  910 YQNINTLKKVDEYIKicentkesiEKFHNKQNILKEILNKNIDTIKESNLIEKSYKDKFdntlidkineLDKAFKDASLN 989

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1952 ANKSHAKELQELLREKQ------------QEVKQLQKDCIRYLERISALEKTVKALEFV-HTESQKDLDVTKGNLAQAVE 2018
Cdd:TIGR01612  990 DYEAKNNELIKYFNDLKanlgknkenmlyHQFDEKEKATNDIEQKIEDANKNIPNIEIAiHTSIYNIIDEIEKEIGKNIE 1069

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2019 HR-----KKAQAELSSFKIL--------LDDTQSEaarvlaDNLKLKKELQSNKESIKSQIKQKDEDL--LRRLEQAEEK 2083
Cdd:TIGR01612 1070 LLnkeilEEAEINITNFNEIkeklkhynFDDFGKE------ENIKYADEINKIKDDIKNLDQKIDHHIkaLEEIKKKSEN 1143

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2084 HRKEKKNMQEKLDALHREKAH---VEETLAEIQVSLTRKDQEmKELQGSLDSTLAQLAAFTKSMSSLQDDRD-------- 2152
Cdd:TIGR01612 1144 YIDEIKAQINDLEDVADKAISnddPEEIEKKIENIVTKIDKK-KNIYDEIKKLLNEIAEIEKDKTSLEEVKGinlsygkn 1222

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2153 ------RVIDEAKKWERRFGDAIQTKEEEV-RLKEENCIALKDQLRQMAIHMEelkITVSRLEHDKEiweSKAQTELQHH 2225
Cdd:TIGR01612 1223 lgklflEKIDEEKKKSEHMIKAMEAYIEDLdEIKEKSPEIENEMGIEMDIKAE---METFNISHDDD---KDHHIISKKH 1296

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2226 QKAYDKLQEENKELT------SQLEDARQLYHDSKNELTKLESELKSLKDQTTDLNNSLEKckeheNNLEGIIKQQEADI 2299
Cdd:TIGR01612 1297 DENISDIREKSLKIIedfseeSDINDIKKELQKNLLDAQKHNSDINLYLNEIANIYNILKL-----NKIKKIIDEVKEYT 1371

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2300 QNCKFSCEQLETDLAASRELTSRLHDEINAKE--QKIISLLSGKE--EAIQ---------LAVEELHQQHSKEIKEL-EN 2365
Cdd:TIGR01612 1372 KEIEENNKNIKDELDKSEKLIKKIKDDINLEEckSKIESTLDDKDidECIKkikelknhiLSEESNIDTYFKNADENnEN 1451

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2366 LL------------SQEEEENVALEEEN---------KRALEKTNQLTEALEAIKKESFEQKAQLDSFVKSMSSL----- 2419
Cdd:TIGR01612 1452 VLllfkniemadnkSQHILKIKKDNATNdhdfninelKEHIDKSKGCKDEADKNAKAIEKNKELFEQYKKDVTELlnkys 1531

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2420 -----------QDDRDRIVSDYRQLE----------ERHLSAILEKDQLIQDAAAENNKLKEEMRGLRSHMDDLNSENAK 2478
Cdd:TIGR01612 1532 alaiknkfaktKKDSEIIIKEIKDAHkkfileaeksEQKIKEIKKEKFRIEDDAAKNDKSNKAAIDIQLSLENFENKFLK 1611

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2479 LDaelvQYRRDLNEVIAIKDSQQKQL----LDAQLQQNKELRNECTKLEERLKGLEAEKQSLQMSsdalQKEKQGLSKEI 2554
Cdd:TIGR01612 1612 IS----DIKKKINDCLKETESIEKKIssfsIDSQDTELKENGDNLNSLQEFLESLKDQKKNIEDK----KKELDELDSEI 1683

                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2555 KNLQTQLTALQEEGTLGVYHA---QLKAKEEELQRLNMALSSSQKR------TADLEeelvcvQKEATRKVSEIEDQLKK 2625
Cdd:TIGR01612 1684 EKIEIDVDQHKKNYEIGIIEKikeIAIANKEEIESIKELIEPTIENlissfnTNDLE------GIDPNEKLEEYNTEIGD 1757

                         1290      1300      1310      1320      1330      1340      1350      1360
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2626 ELKHLHHDAGIMRNETETAEER---VAELARDLVEMEQKLLTVTKENKDLMA-----QIQAFGRSMSSLQDSRDHA---- 2693
Cdd:TIGR01612 1758 IYEEFIELYNIIAGCLETVSKEpitYDEIKNTRINAQNEFLKIIEIEKKSKSylddiEAKEFDRIINHFKKKLDHVndkf 1837

                         1370      1380      1390      1400      1410      1420      1430      1440
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2694 TEELGDLKKKYDASLKELAQLKEWQDSSREGDVLSQaafplsTSENVLSRLEKLNQQLTSKDEQLLHLSSELESSHN-QV 2772
Cdd:TIGR01612 1838 TKEYSKINEGFDDISKSIENVKNSTDENLLFDILNK------TKDAYAGIIGKKYYSYKDEAEKIFINISKLANSINiQI 1911

                         1450      1460      1470      1480      1490      1500      1510      1520
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2773 QSiSKAMTSLQNERDRLWSELE-------KFRKSEEGKQRAAAPSAASSPAEVQSLKKAMSSLQNDRDRLLKELKNlQQQ 2845
Cdd:TIGR01612 1912 QN-NSGIDLFDNINIAILSSLDsekedtlKFIPSPEKEPEIYTKIRDSYDTLLDIFKKSQDLHKKEQDTLNIIFEN-QQL 1989

                         1530      1540      1550      1560      1570      1580      1590      1600
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2846 Y--LQMSQEMTE-LRPLKAQLQESQDQTKALQVMEEELRQENLSWQH--------ELRQLRMEKNSWELHERRMKEQFLM 2914
Cdd:TIGR01612 1990 YekIQASNELKDtLSDLKYKKEKILNDVKLLLHKFDELNKLSCDSQNydtilelsKQDKIKEKIDNYEKEKEKFGIDFDV 2069

                         1610      1620      1630      1640      1650      1660      1670      1680
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2915 AISDKdqqlgHLQSLLRELRSSSQAQILSTQYQRQASPETSASLDGSQKLVYETELLRTqlndslkEIHQKELRIQQLNS 2994
Cdd:TIGR01612 2070 KAMEE-----KFDNDIKDIEKFENNYKHSEKDNHDFSEEKDNIIQSKKKLKELTEAFNT-------EIKIIEDKIIEKND 2137

                         1690      1700      1710      1720
                   ....*....|....*....|....*....|....*....|....
gi 1039751022 2995 KFSQLLE-EKNVLSTQLSDASQSLRENQHHYSNLFNHCAILEKE 3037
Cdd:TIGR01612 2138 LIDKLIEmRKECLLFSYATLVETLKSKVINHSEFITSAAKFSKD 2181
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1117-1593 5.15e-05

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 49.27  E-value: 5.15e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1117 ELEGRILDLEKDKTQLQKKLQEAliarKAILKKAQEKekqlKEELREQKDAYHHLQGQFHEQNKEKENIADQLRQLQCQA 1196
Cdd:PRK02224   217 ELDEEIERYEEQREQARETRDEA----DEVLEEHEER----REELETLEAEIEDLRETIAETEREREELAEEVRDLRERL 288

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1197 ---RESIDRQLPGTGQQEPGPPAPSLEGISLEDTEPASESDLHAAQPSPPG-ETAALQATVSVAQIQAQLKEMEVEKEEL 1272
Cdd:PRK02224   289 eelEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQAhNEEAESLREDADDLEERAEELREEAAEL 368

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1273 ELKVSSIASELAKKSEEVLLLQDQINEQGLEIQNLKAASVEAQAHTELLKQELESSQLKVAGLE-HLKTL---------- 1341
Cdd:PRK02224   369 ESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAELEaTLRTArerveeaeal 448

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1342 ----------QPELDALH-KHMGQKEEEVNYLYGQLSEKEQTLTTVQ------TEMVEQERLIKALHTQLEMQAK---EH 1401
Cdd:PRK02224   449 leagkcpecgQPVEGSPHvETIEEDRERVEELEAELEDLEEEVEEVEerleraEDLVEAEDRIERLEERREDLEEliaER 528

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1402 EERLKQAQVEICELKKKPTELEEETNAKQQLQRKLQAALISRKEALKENKSLQEQLSSARDAVERLTKSLADVES--QVS 1479
Cdd:PRK02224   529 RETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLERIRTLLAAIADaeDEI 608

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1480 VQNQEKDAVLG--------KLTILQEERDKLIAEMDRFLLEN-----QSLSGSCESLKLALGGLTEDKEKLMEELESVRS 1546
Cdd:PRK02224   609 ERLREKREALAelnderreRLAEKRERKRELEAEFDEARIEEaredkERAEEYLEQVEEKLDELREERDDLQAEIGAVEN 688

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|....*..
gi 1039751022 1547 SkMAESTEWQEKHKELQKEYEVLlqsyENVSNEAERIQHVVESVRQE 1593
Cdd:PRK02224   689 E-LEELEELRERREALENRVEAL----EALYDEAEELESMYGDLRAE 730
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1950-2164 5.47e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 48.61  E-value: 5.47e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1950 GPANKSHAKELQELLREKQQEVKQLQKDCIRYLERISALEKTVKALEFVHTESQKDLDVTKGNLAQAVEHRKKAQAELSS 2029
Cdd:COG4942     15 AAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAE 94

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2030 FKILLDDTQSEAARVLA--------DNLKLKKELQSNKESIKS-----QIKQKDEDLLRRLEQAEEKHRKEKKNMQEKLD 2096
Cdd:COG4942     95 LRAELEAQKEELAELLRalyrlgrqPPLALLLSPEDFLDAVRRlqylkYLAPARREQAEELRADLAELAALRAELEAERA 174

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1039751022 2097 ALHREKAHVEETLAEIQVSLTRKDQEMKELQGSLDSTLAQLAAFTKSMSSLQDDRDRVIDEAKKWERR 2164
Cdd:COG4942    175 ELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1570-2234 7.22e-05

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 48.52  E-value: 7.22e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1570 LQSYENVSNEAERIQHVVESVRQEKQELYAKLRSTESDKREREKQLQDAEQEMeemkekmrkfaKSKQQKILELEEENDR 1649
Cdd:PRK03918   157 LDDYENAYKNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREI-----------NEISSELPELREELEK 225

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1650 LRAEaqpvggtgesmeallssnsslKEELEKITLEHKTLSKEFEALMAEKDALSEETRNLKLQVEAQVLKQASLEatEKS 1729
Cdd:PRK03918   226 LEKE---------------------VKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELE--EKV 282

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1730 DEPKDVIEEVTQAVVGKSQERDALSDSAKLEDSEAILMgdgakpgvsetfSSHDDIKNYLQQLDQLKGRIAELEMEKQKD 1809
Cdd:PRK03918   283 KELKELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLE------------EEINGIEERIKELEEKEERLEELKKKLKEL 350

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1810 RELSQALEnEKNALLTQISAKDSELKLLEEEVTKRTTlnQQIQEELCRVTKLKETAEEEKDDLEERlmnqlaelngsIGN 1889
Cdd:PRK03918   351 EKRLEELE-ERHELYEEAKAKKEELERLKKRLTGLTP--EKLEKELEELEKAKEEIEEEISKITAR-----------IGE 416

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1890 YYQDVTDAQIKNEQLESEMRNLQRCVSEL-EEEKQQLVKEKTKVESEIRKEymekiqgaqkgpankshAKELQELLREKQ 1968
Cdd:PRK03918   417 LKKEIKELKKAIEELKKAKGKCPVCGRELtEEHRKELLEEYTAELKRIEKE-----------------LKEIEEKERKLR 479

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1969 QEVKQLQKDcIRYLERISALEKTVKALEFVHTESQKdldvtkgnlaQAVEHRKKAQAELSSFKILLDDTQSEaARVLADN 2048
Cdd:PRK03918   480 KELRELEKV-LKKESELIKLKELAEQLKELEEKLKK----------YNLEELEKKAEEYEKLKEKLIKLKGE-IKSLKKE 547

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2049 LKLKKELQSNKESIKSQIKQKDEDLLRRLEQAEEKHRKEKKNMQEKLDALhrEKAHVEE-TLAEIQVSLTRKDQEMKELQ 2127
Cdd:PRK03918   548 LEKLEELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERLKEL--EPFYNEYlELKDAEKELEREEKELKKLE 625

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2128 GSLDSTLAQLAAFTKSMSSLQDDrdrvIDEAKKweRRFGDAIQTKEEEVRLKEENCIALKDQLRQMAIHMEELKITVSRL 2207
Cdd:PRK03918   626 EELDKAFEELAETEKRLEELRKE----LEELEK--KYSEEEYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKL 699

                          650       660
                   ....*....|....*....|....*..
gi 1039751022 2208 EHDKEIWEsKAQTELQHHQKAYDKLQE 2234
Cdd:PRK03918   700 KEELEERE-KAKKELEKLEKALERVEE 725
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 2439-3019 7.42e-05

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 48.68  E-value: 7.42e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2439 SAILEKDQLIQDAAAENNKLKEEMRGLRSHM----DDLNSENAKLDAELVQYRRDLNEViaikDSQQKQLLDAQLQQNK- 2513
Cdd:pfam12128  269 SDETLIASRQEERQETSAELNQLLRTLDDQWkekrDELNGELSAADAAVAKDRSELEAL----EDQHGAFLDADIETAAa 344

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2514 ------ELRNECTKLEERLKGLEAEKQSLQMSSDAL-QKEKQGLSKEIKNLQTQLTALQEEGTLG------VYHAQLKAK 2580
Cdd:pfam12128  345 dqeqlpSWQSELENLEERLKALTGKHQDVTAKYNRRrSKIKEQNNRDIAGIKDKLAKIREARDRQlavaedDLQALESEL 424

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2581 EEELQRLNMALSSSQKRTADLEEELVCVQKEATRKVSEIEDQLKK--ELKHLHHDAGIMRNETETA--EERVAELARD-- 2654
Cdd:pfam12128  425 REQLEAGKLEFNEEEYRLKSRLGELKLRLNQATATPELLLQLENFdeRIERAREEQEAANAEVERLqsELRQARKRRDqa 504

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2655 ---LVEMEQKLLTVTKENKDLMAQIqaFGRSMSSLQDSRDHATEELGDLKKKYDASLKELAQLKEWQDSSREGDVLSQAA 2731
Cdd:pfam12128  505 seaLRQASRRLEERQSALDELELQL--FPQAGTLLHFLRKEAPDWEQSIGKVISPELLHRTDLDPEVWDGSVGGELNLYG 582

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2732 FPLSTSENVLSRLEKLNQQLTSKDEQllhLSSELESSHNQVQSISKAMTSLQNERDRLWSELEkfrkseegkqraaapsa 2811
Cdd:pfam12128  583 VKLDLKRIDVPEWAASEEELRERLDK---AEEALQSAREKQAAAEEQLVQANGELEKASREET----------------- 642

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2812 asspaevqslkKAMSSLQNDRDRlLKELKNLQQQYLQMSQEMTELRPLKAQlQESQDQTKALQVMEEELRQENLSWQHEL 2891
Cdd:pfam12128  643 -----------FARTALKNARLD-LRRLFDEKQSEKDKKNKALAERKDSAN-ERLNSLEAQLKQLDKKHQAWLEEQKEQK 709

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2892 RQLRMEKNswelherrmkEQFLMAISDKDQQLGHLQSLLRELRSSSQAQI--LSTQYQRQAspetsASLDGSQKLVYETE 2969
Cdd:pfam12128  710 REARTEKQ----------AYWQVVEGALDAQLALLKAAIAARRSGAKAELkaLETWYKRDL-----ASLGVDPDVIAKLK 774

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1039751022 2970 LLRTQLNDSLKEIHQKELRIQQLNSKF-SQLLEEKNVLSTQLSDASQSLRE 3019
Cdd:pfam12128  775 REIRTLERKIERIAVRRQEVLRYFDWYqETWLQRRPRLATQLSNIERAISE 825
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1110-1976 7.77e-05

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 48.81  E-value: 7.77e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1110 GEEHWKPELEGRILDLEKDKTQLQKKLQEALIARKAILKKAQEKEKQLKEELREQKDAYHHLQGQFHEQNKEKENIADQL 1189
Cdd:pfam02463  152 PERRLEIEEEAAGSRLKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDY 231

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1190 RQLQCQARESIDRQLPGTGQQEPGPPAPSLEGISLEDTEPASESDLHAAQPSppGETAALQATVSVAQIQAQLKEMEVEK 1269
Cdd:pfam02463  232 LKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKL--QEEELKLLAKEEEELKSELLKLERRK 309

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1270 EELELKVSSIASELAKKSEEVLLLQDQINEQGLEIQNLKAASveaqahTELLKQELESSQLKVAGLEHLKTLQPELDALH 1349
Cdd:pfam02463  310 VDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKR------EAEEEEEEELEKLQEKLEQLEEELLAKKKLES 383

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1350 KHMGQKEEEVNYLYGQLSEKEQTLTTVQTEMVEQERLIKALHTQLEMQAKEhEERLKQAQVEICELKKKPTELEEETNAK 1429
Cdd:pfam02463  384 ERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEE-EEESIELKQGKLTEEKEELEKQELKLLK 462

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1430 QQLQRKLQAALISRKEALKENKSLQEQLSSARDAvERLTKSLADVESQVSVQNQEKDAVLGKLTILQEERDKLIAEMDRF 1509
Cdd:pfam02463  463 DELELKKSEDLLKETQLVKLQEQLELLLSRQKLE-ERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENY 541

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1510 LLENQSL-----------SGSCESLKLALGGLTEDKEKLMEELESVRSSKMAESTEWQEKHKELQKEYEVLLQSYENVSN 1578
Cdd:pfam02463  542 KVAISTAvivevsatadeVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKR 621

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1579 EAERIQHVVESVRQEKQELYAKLRSTESDKREREKQLQDAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEAQPVG 1658
Cdd:pfam02463  622 AKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEI 701

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1659 GTGESMEALLSSNSSLKEE---LEKITLEHKTLSKEFEALMAEKDALSEETRNLKLQVEAQVLKQASLEATEKSDEPKDV 1735
Cdd:pfam02463  702 KKKEQREKEELKKLKLEAEellADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEERE 781

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1736 IEEVtqavvgKSQERDALSDSAKLEDSEAILMgdgakpgvsetfsSHDDIKNYLQQLDQLKGRIAELEMEKQKDRELSQA 1815
Cdd:pfam02463  782 KTEK------LKVEEEKEEKLKAQEEELRALE-------------EELKEEAELLEEEQLLIEQEEKIKEEELEELALEL 842

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1816 LENEKNALLTQISAKDSELKLLEEEVTKRTTLNQQIQEELCRVTKLKETAEEEKDDLEERLMNQLAELNgsiGNYYQDVT 1895
Cdd:pfam02463  843 KEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNL---LEEKENEI 919

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1896 DAQIKNEQLESEMRNLQRCVSELEEEKQQLVKEKTKVESEIRKEYMEKiQGAQKGPANKSHAKELQELLREKQQEVKQLQ 1975
Cdd:pfam02463  920 EERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRLLL-AKEELGKVNLMAIEEFEEKEERYNKDELEKE 998


                   .
gi 1039751022 1976 K 1976
Cdd:pfam02463  999 R 999
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2386-2604 7.94e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.84  E-value: 7.94e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2386 EKTNQLTEALEAIKKESFEQKAQLDSFVKSMSSLQDDRDRIVSDYRQLEERhlsailekdqlIQDAAAENNKLKEEMRGL 2465
Cdd:COG4942     27 AELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQE-----------LAALEAELAELEKEIAEL 95

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2466 RSHMDDLNSENAKLDAELVQYRR--DLNEVIAIKDSQQ--------KQLLDAQLQQNKELRNECTKLEERLKGLEAEKQS 2535
Cdd:COG4942     96 RAELEAQKEELAELLRALYRLGRqpPLALLLSPEDFLDavrrlqylKYLAPARREQAEELRADLAELAALRAELEAERAE 175

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1039751022 2536 LQMSSDALQKEKQGLSKEIKNLQTQLTALQEEgtLGVYHAQLKAKEEELQRLNMALSSSQKRTADLEEE 2604
Cdd:COG4942    176 LEALLAELEEERAALEALKAERQKLLARLEKE--LAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1303-1722 8.98e-05

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 48.23  E-value: 8.98e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1303 EIQNLKAASVEAQAHTELLKQELESSQLKVAGLEHLKTLQPELDALHKHmGQKEEEVNYLYGQLSEKEQTLTTVQTEMVE 1382
Cdd:COG4717     89 EYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEAL-EAELAELPERLEELEERLEELRELEEELEE 167

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1383 QERLIKALHTQLEMQAK----EHEERLKQAQVEICELKKKPTELEEETNAKQQLQRKLQAA---LISRKEALKENKSLQE 1455
Cdd:COG4717    168 LEAELAELQEELEELLEqlslATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEEleqLENELEAAALEERLKE 247

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1456 QLSSARDAVERLTKSLADVESQVSVQNQEKDAVLG-------------KLTILQEERDKLIAEMDRFLLENQSLSGSCES 1522
Cdd:COG4717    248 ARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVlgllallflllarEKASLGKEAEELQALPALEELEEEELEELLAA 327

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1523 LKLALGGLTEDKEKLMEELESVRSS-KMAESTEWQEKHKELQKEYEVLLQSYeNVSNEAERIQHVVESvrQEKQELYAKL 1601
Cdd:COG4717    328 LGLPPDLSPEELLELLDRIEELQELlREAEELEEELQLEELEQEIAALLAEA-GVEDEEELRAALEQA--EEYQELKEEL 404

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1602 RSTESDKREREKQLQDAEQEMEEMKEKMRkfAKSKQQKILELEEENDRLRAEaqpVGGTGESMEALLSSN--SSLKEELE 1679
Cdd:COG4717    405 EELEEQLEELLGELEELLEALDEEELEEE--LEELEEELEELEEELEELREE---LAELEAELEQLEEDGelAELLQELE 479

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|...
gi 1039751022 1680 KITLEHKTLSKEFEALMAEKDALSEETRNLKLQVEAQVLKQAS 1722
Cdd:COG4717    480 ELKAELRELAEEWAALKLALELLEEAREEYREERLPPVLERAS 522
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1547-2116 1.04e-04

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 48.11  E-value: 1.04e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1547 SKMAESTEwQEKHKELQKEYEVllqsyeNVSNEAERIQHVVESVRQEKQELYAKLRSTESDKREREKQLQDAEQEmeemk 1626
Cdd:PRK02224   213 SELAELDE-EIERYEEQREQAR------ETRDEADEVLEEHEERREELETLEAEIEDLRETIAETEREREELAEE----- 280

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1627 ekmrkfAKSKQQKILELEEENDRLRAEAQPVGGTGESMEALLSSNSSLKEELEKITLEHKTLSKEF--EALMAEKDALSE 1704
Cdd:PRK02224   281 ------VRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQAHneEAESLREDADDL 354

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1705 ETRNLKLQVEAQVLKQASLEATEKSDEPKDVIEEVtqavvgksqERDALSDSAKLEDSEAILmgDGAKPGVSETFSSHDD 1784
Cdd:PRK02224   355 EERAEELREEAAELESELEEAREAVEDRREEIEEL---------EEEIEELRERFGDAPVDL--GNAEDFLEELREERDE 423

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1785 IKNYLQQLD----QLKGRIAELE--MEKQKDRELSQALENEKNAllTQISAKDSELKLLEEEVTKRTTLNQQIQEELCRV 1858
Cdd:PRK02224   424 LREREAELEatlrTARERVEEAEalLEAGKCPECGQPVEGSPHV--ETIEEDRERVEELEAELEDLEEEVEEVEERLERA 501

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1859 TKLKETA------EEEKDDLEERLMNQLAELNgsignyyQDVTDAQIKNEQ---LESEMRNLQRCVSELEEEKQQlVKEK 1929
Cdd:PRK02224   502 EDLVEAEdrierlEERREDLEELIAERRETIE-------EKRERAEELRERaaeLEAEAEEKREAAAEAEEEAEE-AREE 573

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1930 TKVESEIRKEYMEKIQGAQKGPANKSHAKELQELLREKQQEVKQLQKDCIRYLERISALEKTVKALEFVHTESqkdldvt 2009
Cdd:PRK02224   574 VAELNSKLAELKERIESLERIRTLLAAIADAEDEIERLREKREALAELNDERRERLAEKRERKRELEAEFDEA------- 646

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2010 kgNLAQAVEHRKKAQAELSSFKILLDDTQSEaarvladnlklKKELQSNKESIKSQIKQKdEDLLRRLEQAEEKHrkekk 2089
Cdd:PRK02224   647 --RIEEAREDKERAEEYLEQVEEKLDELREE-----------RDDLQAEIGAVENELEEL-EELRERREALENRV----- 707

                          570       580
                   ....*....|....*....|....*..
gi 1039751022 2090 nmqEKLDALHREKAHVEETLAEIQVSL 2116
Cdd:PRK02224   708 ---EALEALYDEAEELESMYGDLRAEL 731
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 2648-3002 1.08e-04

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 48.14  E-value: 1.08e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2648 VAELARDLVEMEQKLLTVTKENKDLMAQIQAFGRSMSSLQDSRDHATEELGDLKKKYDASLKELaqLKEWQDSSREgdvl 2727
Cdd:TIGR02169  165 VAEFDRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAERYQALLKEKREYEGYEL--LKEKEALERQ---- 238

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2728 sqaafpLSTSENVLSRLEKLNQQLTSKDEQLLHLSSELESSHNQVQSISKAMTSlqNERDRLWSELEKFrkseEGKQRAA 2807
Cdd:TIGR02169  239 ------KEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGE--EEQLRVKEKIGEL----EAEIASL 306

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2808 APSAASSPAEVQSLKKAMSSLQNDRDRLLKELKNL----QQQYLQMSQEMTELRPLKAQLQESQDQTKALQVMEEELRQE 2883
Cdd:TIGR02169  307 ERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELereiEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDE 386

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2884 NLSWQHELRQLRMEKNSWELHERRM---KEQFLMAISDKDQQLGHLQSLLRELRSSSQAQILSTQYQRQASPETSASLDG 2960
Cdd:TIGR02169  387 LKDYREKLEKLKREINELKRELDRLqeeLQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSK 466

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|..
gi 1039751022 2961 SQKLVYEtelLRTQLNDSLKEIHQKELRIQQLNSKFSQLLEE 3002
Cdd:TIGR02169  467 YEQELYD---LKEEYDRVEKELSKLQRELAEAEAQARASEER 505
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
646-1005 1.09e-04

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 48.11  E-value: 1.09e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  646 QGELERLKTQVLELETSLHTAEETYKRNLsekvKEISSLTQLSEEVKESAEEARSTLAAVTEERDQLLYQVKELDV-LAE 724
Cdd:PRK02224   320 EDRDEELRDRLEECRVAAQAHNEEAESLR----EDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEeIEE 395

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  725 LRARVQELESSLAEAEKQRgldyESQRAQHNLLTEQIHSLSIEAKSKDVKIEALQRELDGVQLQFCEQGTQMKTLQSQLE 804
Cdd:PRK02224   396 LRERFGDAPVDLGNAEDFL----EELREERDELREREAELEATLRTARERVEEAEALLEAGKCPECGQPVEGSPHVETIE 471

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  805 AKEREVREGTERLRDISQEMEGLSQALSQKE--LEIAKMDQLLLEKQKDVETL-----------QQTIQEKDQQVTELSF 871
Cdd:PRK02224   472 EDRERVEELEAELEDLEEEVEEVEERLERAEdlVEAEDRIERLEERREDLEELiaerretieekRERAEELRERAAELEA 551

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  872 SMTEKMVQ---LNEEKFSLGVEIKTLKEQLNLLSRTEEATkEQVEESGAGSSLKLGHDESGQEGLQQ--ELELLRKE--S 944
Cdd:PRK02224   552 EAEEKREAaaeAEEEAEEAREEVAELNSKLAELKERIESL-ERIRTLLAAIADAEDEIERLREKREAlaELNDERRErlA 630

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1039751022  945 EQRKRK--------------LQAALINRKELLQKVSQLEEELAKVREDSRKEIPFGENERRKLEEDRENRDDPEE 1005
Cdd:PRK02224   631 EKRERKreleaefdearieeAREDKERAEEYLEQVEEKLDELREERDDLQAEIGAVENELEELEELRERREALEN 705
46 PHA02562
endonuclease subunit; Provisional
 2487-2716 1.27e-04

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 47.70  E-value: 1.27e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2487 RRDLNE------VIAIKDSQQKQLLDAQLQQNKELRNECTKLEERLKGLEAEKQSLQMSSDALQKEKQG----LSKEIKN 2556
Cdd:PHA02562   152 RRKLVEdlldisVLSEMDKLNKDKIRELNQQIQTLDMKIDHIQQQIKTYNKNIEEQRKKNGENIARKQNkydeLVEEAKT 231

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2557 LQTQLTALQEEgtLGVYHAQLKAKEEELQRLNMALS--SSQKRTADLEEEL--------VCVQK---------EATRKVS 2617
Cdd:PHA02562   232 IKAEIEELTDE--LLNLVMDIEDPSAALNKLNTAAAkiKSKIEQFQKVIKMyekggvcpTCTQQisegpdritKIKDKLK 309

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2618 EIEDQLKKELKHLHHDAGIMrNETETAEERVAELARDLVEMEQKLLTVTKENKDLMAQIQafgrsmsSLQDSRDHATEEL 2697
Cdd:PHA02562   310 ELQHSLEKLDTAIDELEEIM-DEFNEQSKKLLELKNKISTNKQSLITLVDKAKKVKAAIE-------ELQAEFVDNAEEL 381

                          250
                   ....*....|....*....
gi 1039751022 2698 GDLKKKYDASLKELAQLKE 2716
Cdd:PHA02562   382 AKLQDELDKIVKTKSELVK 400
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 1245-1937 1.62e-04

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 47.73  E-value: 1.62e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1245 ETAALQATVSVAQIQAQLKEMEVEKEELELKVSSIASELAKKSEEVLLLQDQINEQGLEIQNLKAASVEA-QAHTELLKQ 1323
Cdd:TIGR00606  404 EDEAKTAAQLCADLQSKERLKQEQADEIRDEKKGLGRTIELKKEILEKKQEELKFVIKELQQLEGSSDRIlELDQELRKA 483

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1324 ELESSQL--------KVAGLEHLKTLQPELDALHKHMGQKEEEVNYLYGQLSEKEqTLTTVQTEMVEQERLIKALHTQLE 1395
Cdd:TIGR00606  484 ERELSKAeknsltetLKKEVKSLQNEKADLDRKLRKLDQEMEQLNHHTTTRTQME-MLTKDKMDKDEQIRKIKSRHSDEL 562

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1396 MQAKEHEERLKQAQVEICELKKKPTELEEETnakQQLQRKLQAALISRKEALKENKSLQEQLSSARDAVERLTKSlADVE 1475
Cdd:TIGR00606  563 TSLLGYFPNKKQLEDWLHSKSKEINQTRDRL---AKLNKELASLEQNKNHINNELESKEEQLSSYEDKLFDVCGS-QDEE 638

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1476 SQVSVQNQEKDAVLGKLTILQEERDKLIAEMDRFLLENQSLSGSCESLKLALGGLTEdkekLMEELESVRSSKMAESTEW 1555
Cdd:TIGR00606  639 SDLERLKEEIEKSSKQRAMLAGATAVYSQFITQLTDENQSCCPVCQRVFQTEAELQE----FISDLQSKLRLAPDKLKST 714

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1556 QEKHKELQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQELYAKLRSTESDKREREKQLQ--DAEQEMEEMKEKMRKFA 1633
Cdd:TIGR00606  715 ESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGtiMPEEESAKVCLTDVTIM 794

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1634 KSKQQKILELEEENDRLRAEAQPVGGTgESMEALLSSNSSLKEELEKITLEHKTLSKEFEALMAEKDALSEETRNLKlqV 1713
Cdd:TIGR00606  795 ERFQMELKDVERKIAQQAAKLQGSDLD-RTVQQVNQEKQEKQHELDTVVSKIELNRKLIQDQQEQIQHLKSKTNELK--S 871

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1714 EAQVLKQASLEATEKSDEPKDVIEEVTQAVVGKSQERDALSDSAKLEDSEAILMGDGAKPGVSETFSSHDDIKNYLQQLD 1793
Cdd:TIGR00606  872 EKLQIGTNLQRRQQFEEQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEELISSKETSNKKAQDKVNDIKEKVK 951

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1794 QLKGRIAELEMEKQ--KDRELSQAlENEKNALLTQISAKDSELKLLEEEV--TKRTTLNQQIQEELCRVTKLKETAEEEK 1869
Cdd:TIGR00606  952 NIHGYMKDIENKIQdgKDDYLKQK-ETELNTVNAQLEECEKHQEKINEDMrlMRQDIDTQKIQERWLQDNLTLRKRENEL 1030

                          650       660       670       680       690       700
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1039751022 1870 DDLEERLMNQLAELNgsignyYQDVTDAQIKNEQLESEMRNLQRCVSELEEEKQQLVKEKTKVESEIR 1937
Cdd:TIGR00606 1031 KEVEEELKQHLKEMG------QMQVLQMKQEHQKLEENIDLIKRNHVLALGRQKGYEKEIKHFKKELR 1092
PRK11281 PRK11281
mechanosensitive channel MscK;
2230-2593 1.80e-04

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 47.60  E-value: 1.80e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2230 DKLQEENKELTSQLEDARQLYHDSKNELTKLESELKSLKDQTTDlNNSLEKckehennLEGIIKQQEADIQNCKFSCEQL 2309
Cdd:PRK11281    76 DRQKEETEQLKQQLAQAPAKLRQAQAELEALKDDNDEETRETLS-TLSLRQ-------LESRLAQTLDQLQNAQNDLAEY 147

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2310 ETDLAASRELTSRLHDEINA---KEQKIISLLSGKEEAIQLAVEELHQQHSKEIKELENLLSQeeeenvaleeeNKRALE 2386
Cdd:PRK11281   148 NSQLVSLQTQPERAQAALYAnsqRLQQIRNLLKGGKVGGKALRPSQRVLLQAEQALLNAQNDL-----------QRKSLE 216

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2387 KTNQLTEALEAIKKESFEQKAQLDSFVKSMSSLQDDRDRIVSD--YRQLEERHLSAILEKDQLIQDAAAENNKLKEEMRG 2464
Cdd:PRK11281   217 GNTQLQDLLQKQRDYLTARIQRLEHQLQLLQEAINSKRLTLSEktVQEAQSQDEAARIQANPLVAQELEINLQLSQRLLK 296

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2465 LRSHMDDLNSENAK----LDaELVQYRRDLNEVI-AIKDS--------QQKQLLdAQLQQNKELRNECTKLeeRLKGLEA 2531
Cdd:PRK11281   297 ATEKLNTLTQQNLRvknwLD-RLTQSERNIKEQIsVLKGSlllsrilyQQQQAL-PSADLIEGLADRIADL--RLEQFEI 372

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1039751022 2532 EKQSLQMSSDA------LQKEKQGLSKEIKNlqtQLTALqeegtlgvyhaqLKAKEEELQRLNMALSS 2593
Cdd:PRK11281   373 NQQRDALFQPDayidklEAGHKSEVTDEVRD---ALLQL------------LDERRELLDQLNKQLNN 425
PRK11281 PRK11281
mechanosensitive channel MscK;
1339-1516 1.89e-04

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 47.60  E-value: 1.89e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1339 KTLQPELDALHKHmGQKEEEVNYLYGQLsekEQTLTTV-QTEMVEQErlikalHTQLEMQAKEHEERLKQAQVEICELKK 1417
Cdd:PRK11281    39 ADVQAQLDALNKQ-KLLEAEDKLVQQDL---EQTLALLdKIDRQKEE------TEQLKQQLAQAPAKLRQAQAELEALKD 108

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1418 KPTELEEETNAKQ---QLQRKLQAALISRKEALKENKSLQEQLSSARDAVERLTKSLAdvESQVSVQ---NQEKDAVLGK 1491
Cdd:PRK11281   109 DNDEETRETLSTLslrQLESRLAQTLDQLQNAQNDLAEYNSQLVSLQTQPERAQAALY--ANSQRLQqirNLLKGGKVGG 186

                          170       180       190
                   ....*....|....*....|....*....|....
gi 1039751022 1492 LTILQEERDKLIAEMD---------RFLLENQSL 1516
Cdd:PRK11281   187 KALRPSQRVLLQAEQAllnaqndlqRKSLEGNTQ 220
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 1321-1605 2.01e-04

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 47.23  E-value: 2.01e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1321 LKQELES--SQLKVAGLEHLKTLQPELDA-----LHKHMGQKEEEVNYLyGQLSEKEQTLTTVQTEMVEQErlikalhtq 1393
Cdd:PRK05771    14 LKSYKDEvlEALHELGVVHIEDLKEELSNerlrkLRSLLTKLSEALDKL-RSYLPKLNPLREEKKKVSVKS--------- 83

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1394 LEMQAKEHEERLKQAQVEICELKKKPTELEEEtnaKQQLQRKLQAALISRK-----EALKENKSLQEQLSSARDAVERLT 1468
Cdd:PRK05771    84 LEELIKDVEEELEKIEKEIKELEEEISELENE---IKELEQEIERLEPWGNfdldlSLLLGFKYVSVFVGTVPEDKLEEL 160

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1469 KSLADVESQVSV-QNQEKDAVLgkLTILQEERDKLIAEMDRFLLENQSLSGSceslklalGGLTEDKEKLMEELESVRSS 1547
Cdd:PRK05771   161 KLESDVENVEYIsTDKGYVYVV--VVVLKELSDEVEEELKKLGFERLELEEE--------GTPSELIREIKEELEEIEKE 230

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1039751022 1548 KmaESTEwqEKHKELQKEYE-VLLQSYENVSNEAERiqhvvesvrqekQELYAKLRSTE 1605
Cdd:PRK05771   231 R--ESLL--EELKELAKKYLeELLALYEYLEIELER------------AEALSKFLKTD 273
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 1551-2125 2.04e-04

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 47.27  E-value: 2.04e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1551 ESTEWQEKHKELQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQELYAKLRSTESDKREREKQLQDAEQEMEEMKEKMR 1630
Cdd:TIGR00618  270 EELRAQEAVLEETQERINRARKAAPLAAHIKAVTQIEQQAQRIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQT 349

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1631 KFAKSKQQKI-----LELEEENDRLRAEAQPVGGTGESMEALLSSNSSLKEELEKITLEHKTLSKEFEALMAEKDALSEE 1705
Cdd:TIGR00618  350 LHSQEIHIRDahevaTSIREISCQQHTLTQHIHTLQQQKTTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAHA 429

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1706 TRNLKLQVEAQVLKQASLEATEKSDEPKDV--------IEEVTQAVVGKSQERDALSDSAKLEDSEAILMGDGAKPGVSE 1777
Cdd:TIGR00618  430 KKQQELQQRYAELCAAAITCTAQCEKLEKIhlqesaqsLKEREQQLQTKEQIHLQETRKKAVVLARLLELQEEPCPLCGS 509

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1778 TFSSHDDIKNYLQ------QLDQLKGRIAELEMEKQKDRELSQALENEKNALLTQISAKDSELKLLEEEVTKRTTLNQQI 1851
Cdd:TIGR00618  510 CIHPNPARQDIDNpgpltrRMQRGEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNL 589

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1852 QEELCRVTKLKETAEEEKDDLEERLMNQLAELNGSIGNYYQDVTDAQIKNEQLESEM---RNLQRCVSELEEEKQQLVKE 1928
Cdd:TIGR00618  590 QNITVRLQDLTEKLSEAEDMLACEQHALLRKLQPEQDLQDVRLHLQQCSQELALKLTalhALQLTLTQERVREHALSIRV 669

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1929 KTKVESEIRKEYMEKIQG-AQKGPANKSHAKELQELLREKQQEVKQLQKDCIRYLERISALEKTVKALEFVHTESQKDLD 2007
Cdd:TIGR00618  670 LPKELLASRQLALQKMQSeKEQLTYWKEMLAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKELM 749

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2008 VTKGNLAQAVEHRKKAQAELSSFKILLDDTQSEAARVLADNLKLKKELQSNKESIKSQIKQKDEDLLRRLEQAEEKHRKE 2087
Cdd:TIGR00618  750 HQARTVLKARTEAHFNNNEEVTAALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQCETLVQE 829

                          570       580       590
                   ....*....|....*....|....*....|....*...
gi 1039751022 2088 KKNMQEKLDALHREKAHVEETLAEIQVSLTRKDQEMKE 2125
Cdd:TIGR00618  830 EEQFLSRLEEKSATLGEITHQLLKYEECSKQLAQLTQE 867
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
687-1078 2.15e-04

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 47.34  E-value: 2.15e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  687 LSEEVKESAEEARSTLAAVTEERDQLLYQVKELDVLAELRARVQELESSLAEAEKQRGLDYESQRAQHNLLTEQIHSLSI 766
Cdd:PRK02224   277 LAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLEE 356

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  767 EAKSKDVKIEALQRELDGVQLQFCEQGTQMKTLQSQLEAKEREVREGTERLRDISQEMEGLSQALSQKELEIAKMDQLLL 846
Cdd:PRK02224   357 RAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAELEATLR 436

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  847 EKQKDVETLQQ---------------------TIQEKDQQVTELSFSMTEKMVQLN--EEKFSLGVEIKTLKEQLNLLSR 903
Cdd:PRK02224   437 TARERVEEAEAlleagkcpecgqpvegsphveTIEEDRERVEELEAELEDLEEEVEevEERLERAEDLVEAEDRIERLEE 516

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  904 TEEATKEQVEESGAGsslkLGHDESGQEGLQQELELLRKESEQRKRKLQAALINRKELLQKVSQLEEELAKVRE------ 977
Cdd:PRK02224   517 RREDLEELIAERRET----IEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKEriesle 592

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  978 DSRKEIPFGENERRKLEEDRENRDDPEEWGTSKwREVEASLKQTISEKEVELEGirrdlkektAAEEELQAVVQRMTRDL 1057
Cdd:PRK02224   593 RIRTLLAAIADAEDEIERLREKREALAELNDER-RERLAEKRERKRELEAEFDE---------ARIEEAREDKERAEEYL 662

                          410       420
                   ....*....|....*....|.
gi 1039751022 1058 QSKTKQIDLLQEEVTENQATI 1078
Cdd:PRK02224   663 EQVEEKLDELREERDDLQAEI 683
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2477-2707 2.23e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 46.68  E-value: 2.23e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2477 AKLDAELVQYRRDLNEVIAikdsQQKQLLDAQLQQNKELRNECTKLEERLKGLEAEKQSLQMSSDALQKEKQGLSKEIKN 2556
Cdd:COG4942     19 ADAAAEAEAELEQLQQEIA----ELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAE 94

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2557 LQTQLTALQEEGTLGVYHAQLKAKEEELQRLNMALSSSQK-RTADLEEELVCVQKEATRKVSEIEDQLKKELKHLHHDAG 2635
Cdd:COG4942     95 LRAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAvRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERA 174

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1039751022 2636 IMRNETETAEERVAELARDLVEMEQKLLTVTKENKDLMAQIQAFGRSMSSLQDSRDHATEELGDLKKKYDAS 2707
Cdd:COG4942    175 ELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAA 246
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2501-2720 2.27e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 46.30  E-value: 2.27e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2501 QKQLLDAQLQQNKELRNECTKLEERLKGLEAEKQSLQMSSDALQKEKQGLSKEIKNLQTQLTALQEEgtlgvyHAQLKAK 2580
Cdd:COG4942     18 QADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAE------LAELEKE 91

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2581 EEELQRlnmalsSSQKRTADLEEELVCVQKeaTRKVSEIEDQLK-KELKHLHHDAGIMRNETETAEERVAELARDLVEME 2659
Cdd:COG4942     92 IAELRA------ELEAQKEELAELLRALYR--LGRQPPLALLLSpEDFLDAVRRLQYLKYLAPARREQAEELRADLAELA 163

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1039751022 2660 QKLLTVTKENKDLMAQIQAFGRSMSSLQDSRDHATEELGDLKKKYDASLKELAQLKEWQDS 2720
Cdd:COG4942    164 ALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEE 224
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 769-1050 2.28e-04

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 46.84  E-value: 2.28e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  769 KSKDVKIEALQrELDGVQLQFCEQGTQMKTLqSQLEAKEREVREGTERLRDISQEmEGLSQALsQKELEIAKMDQLLLEK 848
Cdd:PRK05771    16 SYKDEVLEALH-ELGVVHIEDLKEELSNERL-RKLRSLLTKLSEALDKLRSYLPK-LNPLREE-KKKVSVKSLEELIKDV 91

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  849 QKDVETLQQTIQEKDQQVTELsfsmTEKMVQLNEEKF------SLGVEIKTLKEQLNLLSRTEEATKEQVEESGAgsslk 922
Cdd:PRK05771    92 EEELEKIEKEIKELEEEISEL----ENEIKELEQEIErlepwgNFDLDLSLLLGFKYVSVFVGTVPEDKLEELKL----- 162

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  923 lghdESGQEGLqqelellrKESEQRKRKLQAALINRKELLQKVsqlEEELAKVrEDSRKEIPfgenerrkleedrenrdd 1002
Cdd:PRK05771   163 ----ESDVENV--------EYISTDKGYVYVVVVVLKELSDEV---EEELKKL-GFERLELE------------------ 208

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*...
gi 1039751022 1003 peEWGTSKwrEVEASLKQTISEKEVELEGIRRDLKEKTAAEEELQAVV 1050
Cdd:PRK05771   209 --EEGTPS--ELIREIKEELEEIEKERESLLEELKELAKKYLEELLAL 252
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
774-989 2.48e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 46.83  E-value: 2.48e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  774 KIEALQRELDGVQLQFCEQGTQMKTLQSQLEA--KEREVREGTERLRDISQEMEGLSQALSQKELEIAKmdqlLLEKQKD 851
Cdd:COG4913    611 KLAALEAELAELEEELAEAEERLEALEAELDAlqERREALQRLAEYSWDEIDVASAEREIAELEAELER----LDASSDD 686

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  852 VETLQQTIQEKDQQVTElsfsmtekmvqLNEEKFSLGVEIKTLKEQLNLLSRTEEATKEQVEESGAGsslklghdesGQE 931
Cdd:COG4913    687 LAALEEQLEELEAELEE-----------LEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDL----------ARL 745

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1039751022  932 GLQQELELLRKESEQRK--RKLQAALINRKELLQ-KVSQLEEELAKVREDSRKEIPFGENE 989
Cdd:COG4913    746 ELRALLEERFAAALGDAveRELRENLEERIDALRaRLNRAEEELERAMRAFNREWPAETAD 806
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 1807-2657 2.60e-04

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 47.09  E-value: 2.60e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1807 QKDRELSQALENEKNAlltqisakDSELKLLEEEVTKRTTLNQQIQEELCRVTKLKETAEEekddLEERLMNQLAELNGS 1886
Cdd:pfam01576    9 AKEEELQKVKERQQKA--------ESELKELEKKHQQLCEEKNALQEQLQAETELCAEAEE----MRARLAARKQELEEI 76

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1887 IGNYYQDVTDAQIKNEQLESEMRNLQRCVSELEEE-------KQQLVKEKTKVESEIRKEYMEKIQGAQKGPANKSHAKE 1959
Cdd:pfam01576   77 LHELESRLEEEEERSQQLQNEKKKMQQHIQDLEEQldeeeaaRQKLQLEKVTTEAKIKKLEEDILLLEDQNSKLSKERKL 156

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1960 LQEL-------LREKQQEVKQLQKDCIRYLERISALEKTVKALEFVHTESQKDLDVTKGNLAQAVEHRKKAQAELSSFKI 2032
Cdd:pfam01576  157 LEERiseftsnLAEEEEKAKSLSKLKNKHEAMISDLEERLKKEEKGRQELEKAKRKLEGESTDLQEQIAELQAQIAELRA 236

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2033 LLDDTQSEAARVLA---DNLKLKKELQSNKESIKSQIKQKDEDLLRRlEQAEEKHRKEKKNMQEKLDALHREKAHVEETL 2109
Cdd:pfam01576  237 QLAKKEEELQAALArleEETAQKNNALKKIRELEAQISELQEDLESE-RAARNKAEKQRRDLGEELEALKTELEDTLDTT 315

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2110 AEIQVSLTRKDQEMKELQGSLDSTL----AQLAAFTKSMSSLQDDRDRVIDEAKKWERRFGDAIQTKEE-------EVRL 2178
Cdd:pfam01576  316 AAQQELRSKREQEVTELKKALEEETrsheAQLQEMRQKHTQALEELTEQLEQAKRNKANLEKAKQALESenaelqaELRT 395

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2179 KEENCIALKDQLRQMAIHMEELKITVSRLEHDKEIWE---SKAQTELQH-------HQKAYDKLQEENKELTSQLEDARQ 2248
Cdd:pfam01576  396 LQQAKQDSEHKRKKLEGQLQELQARLSESERQRAELAeklSKLQSELESvssllneAEGKNIKLSKDVSSLESQLQDTQE 475

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2249 LYHDSKNELTKLESELKSLKDQTTDLNNSLEKCKEHENNLEGIIKQQEADIQNCKFSCEQLETDLAASRELTSRLHDEIN 2328
Cdd:pfam01576  476 LLQEETRQKLNLSTRLRQLEDERNSLQEQLEEEEEAKRNVERQLSTLQAQLSDMKKKLEEDAGTLEALEEGKKRLQRELE 555

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2329 AKEQkiisllsgKEEAIQLAVEELHQQHSKEIKELENLLSQEEEENVALEEENKR--------ALEKT--NQLTEALEAI 2398
Cdd:pfam01576  556 ALTQ--------QLEEKAAAYDKLEKTKNRLQQELDDLLVDLDHQRQLVSNLEKKqkkfdqmlAEEKAisARYAEERDRA 627

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2399 KKESFEQKAQLDSFVKSMSSLQDDRDRIVSDYRQLEERHLSAILEKDQL---IQDAAAENNKLKEEMRGLRSHMDDLN-- 2473
Cdd:pfam01576  628 EAEAREKETRALSLARALEEALEAKEELERTNKQLRAEMEDLVSSKDDVgknVHELERSKRALEQQVEEMKTQLEELEde 707

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2474 ---SENAKLDAEL------VQYRRDLNEVIAIKDSQQKQLLDAQLQQNKELRNECTKLEERL---KGLEAEKQSLQMSSD 2541
Cdd:pfam01576  708 lqaTEDAKLRLEVnmqalkAQFERDLQARDEQGEEKRRQLVKQVRELEAELEDERKQRAQAVaakKKLELDLKELEAQID 787

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2542 ALQKEKQGLSKEIKNLQTQLTALQEEgtlgvyhaqlkAKEEELQRLNMALSS--SQKRTADLEEELVCVQKE------AT 2613
Cdd:pfam01576  788 AANKGREEAVKQLKKLQAQMKDLQRE-----------LEEARASRDEILAQSkeSEKKLKNLEAELLQLQEDlaaserAR 856

                          890       900       910       920
                   ....*....|....*....|....*....|....*....|....
gi 1039751022 2614 RKVSEIEDQLKKELKHLHHDAGIMRNETETAEERVAELARDLVE 2657
Cdd:pfam01576  857 RQAQQERDELADEIASGASGKSALQDEKRRLEARIAQLEEELEE 900
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
649-831 2.63e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 46.83  E-value: 2.63e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  649 LERLKTQVLELETSLHTAEETYK------RNLSEKVKEISSLTQLSEEVKESAEeARSTLAAVTEERDQLLyqvKELDVL 722
Cdd:COG4913    612 LAALEAELAELEEELAEAEERLEaleaelDALQERREALQRLAEYSWDEIDVAS-AEREIAELEAELERLD---ASSDDL 687

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  723 AELRARVQELESSLAEAEKQRgldyESQRAQHNLLTEQIHSLSIEAKSKDVKIEALQRELDGVQLQFCEQgtqmKTLQSQ 802
Cdd:COG4913    688 AALEEQLEELEAELEELEEEL----DELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEE----RFAAAL 759

                          170       180       190
                   ....*....|....*....|....*....|
gi 1039751022  803 LEAKEREVREG-TERLRDISQEMEGLSQAL 831
Cdd:COG4913    760 GDAVERELRENlEERIDALRARLNRAEEEL 789
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1247-1472 2.77e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 46.30  E-value: 2.77e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1247 AALQATVSVAQIQAQLKEMEVEKEELELKVSSIASELAKKSEEVLLLQDQINEQGLEIQNLKAASVEAQAHTELLKQELE 1326
Cdd:COG4942     14 AAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIA 93

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1327 SSQLKVAGLEHLktLQPELDALHKHMGQKEEEV---NYLYGQLSEKEQTLTTVQTEMVEQERLIKALHTQLEMQAKEHEE 1403
Cdd:COG4942     94 ELRAELEAQKEE--LAELLRALYRLGRQPPLALllsPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEA 171

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1039751022 1404 RLKQAQVEICELKKKPTELEEETNAKQQLQRKLQAALISRKEALKENKSLQEQLSSARDAVERLTKSLA 1472
Cdd:COG4942    172 ERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAA 240
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 1382-1654 2.77e-04

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 46.46  E-value: 2.77e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1382 EQERLIKALHtqlEMQAkeheerlkqaqVEICELKKKptELEEETNAKQQLQRKLQAALISRKEALKENKSLQEQLSSAR 1461
Cdd:PRK05771    17 YKDEVLEALH---ELGV-----------VHIEDLKEE--LSNERLRKLRSLLTKLSEALDKLRSYLPKLNPLREEKKKVS 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1462 -----DAVERLTKSLADVESQVSVQNQEkdavlgkLTILQEERDKLIAEMDR------FLLENQSLSGScESLKLALGGL 1530
Cdd:PRK05771    81 vksleELIKDVEEELEKIEKEIKELEEE-------ISELENEIKELEQEIERlepwgnFDLDLSLLLGF-KYVSVFVGTV 152

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1531 TEDKEKLMEELESVRSSKMAESTEwqEK-------HKELQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQELyaklrs 1603
Cdd:PRK05771   153 PEDKLEELKLESDVENVEYISTDK--GYvyvvvvvLKELSDEVEEELKKLGFERLELEEEGTPSELIREIKEEL------ 224

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1039751022 1604 tesdkREREKQLQDAEqemeemkEKMRKFAKSKQQKILELEE--ENDRLRAEA 1654
Cdd:PRK05771   225 -----EEIEKERESLL-------EELKELAKKYLEELLALYEylEIELERAEA 265
PRK01156 PRK01156
chromosome segregation protein; Provisional
 1453-2005 2.92e-04

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 46.82  E-value: 2.92e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1453 LQEQLSSARDAVERLTKSLADVESQVSVQNQEKDAVLGKLTILQEERDKLIAEMDRFLLENQSLSGSCESLKLALGGLTE 1532
Cdd:PRK01156   188 LEEKLKSSNLELENIKKQIADDEKSHSITLKEIERLSIEYNNAMDDYNNLKSALNELSSLEDMKNRYESEIKTAESDLSM 267

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1533 DKEK------LMEELESVRSSKMAESTEWQEKHKELQKEYEVLLQSYENVSNEAERIQHVVESVrQEKQELYAKLRSTES 1606
Cdd:PRK01156   268 ELEKnnyykeLEERHMKIINDPVYKNRNYINDYFKYKNDIENKKQILSNIDAEINKYHAIIKKL-SVLQKDYNDYIKKKS 346

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1607 DKREREKQLQDAEQEMEEMKEKMRKFaKSKQQKILELEEENDRLRAEAQPVGGTGE-SMEALLSSNSSLKEELEKITLEH 1685
Cdd:PRK01156   347 RYDDLNNQILELEGYEMDYNSYLKSI-ESLKKKIEEYSKNIERMSAFISEILKIQEiDPDAIKKELNEINVKLQDISSKV 425

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1686 KTLSKEFEALMAEKDALSEETRNLKLQVEAQVLkqASLEATEKSdepKDVIEEVTQAVVGKSQERDALSDSAKLEDSEAI 1765
Cdd:PRK01156   426 SSLNQRIRALRENLDELSRNMEMLNGQSVCPVC--GTTLGEEKS---NHIINHYNEKKSRLEEKIREIEIEVKDIDEKIV 500

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1766 LMGDgakpgvSETFSSHDDIKNYLQQLDQLKGRIAELEMEKQKDRELSQAlENEKNALLTQISAKDseLKLLEEEVTKRT 1845
Cdd:PRK01156   501 DLKK------RKEYLESEEINKSINEYNKIESARADLEDIKIKINELKDK-HDKYEEIKNRYKSLK--LEDLDSKRTSWL 571

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1846 TLNQQIQE-ELCRVTKLKETAEEEKDDLEERLM--------------NQLAELNGSIGNY---YQDVTDAQIKNEQLESE 1907
Cdd:PRK01156   572 NALAVISLiDIETNRSRSNEIKKQLNDLESRLQeieigfpddksyidKSIREIENEANNLnnkYNEIQENKILIEKLRGK 651

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1908 MRNLQRCVSELEEEKQQLvKEKTKVESEIRKEYMEKIQGAQKGPANKSHAKELQELLREKQQEVKQLQKDCIRYLERISA 1987
Cdd:PRK01156   652 IDNYKKQIAEIDSIIPDL-KEITSRINDIEDNLKKSRKALDDAKANRARLESTIEILRTRINELSDRINDINETLESMKK 730

                          570
                   ....*....|....*...
gi 1039751022 1988 LEKTVKALEFVHTESQKD 2005
Cdd:PRK01156   731 IKKAIGDLKRLREAFDKS 748
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 158-975 3.48e-04

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 46.50  E-value: 3.48e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  158 QEKEELISTLQTQLSQTQAEQAAQLSSMQQVVREKDARFETQVRLHEDELLQLVTQSDVETEMQQKLRVMQRKLEEHEEA 237
Cdd:pfam02463  173 EALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEE 252

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  238 LL-------GRAQVVDLLQKELTSAEQRNQVLSQQLQLLEAEHNTLKNTMETERQESKTLMEKV---ELEVAERKLSFHN 307
Cdd:pfam02463  253 IEsskqeieKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLkesEKEKKKAEKELKK 332

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  308 LQEEMHQLQGQLERAGQAQADLETQYSALQQRHKTEMEEKTACILSLQKNEQELQSACAALKEENSKLLQEKHDQAAESA 387
Cdd:pfam02463  333 EKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLE 412

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  388 QAMRQLEDQLQQKSKEISQ------FVNKPNLQKNETASQTSLPDVNNEGDQAVMEETVASLQKRVVELENEKGALLLSS 461
Cdd:pfam02463  413 LARQLEDLLKEEKKEELEIleeeeeSIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSR 492

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  462 GELEELKAENEKLSSRITLLEAQNRAGEADG-------------------------TVCEVSTAGTTLLNRSDSSPEENG 516
Cdd:pfam02463  493 QKLEERSQKESKARSGLKVLLALIKDGVGGRiisahgrlgdlgvavenykvaistaVIVEVSATADEVEERQKLVRALTE 572

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  517 QAVLENTFSQKHKELSVLLVEMKEAQEEIAFLKSQLQGKRPEGDYEVLDRREVQLMESEGPPSVTAGDVLCAPSDESSGP 596
Cdd:pfam02463  573 LPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGV 652

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  597 AAEEEQAGMKDRHRASEAGPLNDAGMELSSPKLDGVDKSLAVSHVCQCHQGELERLKTQVLELETSLHTAEETYKRNLSE 676
Cdd:pfam02463  653 SLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQD 732

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  677 KVKEISSLtQLSEEVKESAEEARSTLAAVTEERDQLLYQVKELDVLAELRARVQELESSLAEAEKQRGLDYESQRAQHNL 756
Cdd:pfam02463  733 KINEELKL-LKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELK 811

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  757 LTEQIHSLSIEAKSKDVKIEALQRELDGVQLQFCEQGTQMKTLQSQLEAKEREVREGTERLRDISQEMEglsqalsqkEL 836
Cdd:pfam02463  812 EEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELE---------EQ 882

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  837 EIAKMDQLLLEKQKDVETLQQTIQEKDQQVTELSFSMTEKMVQLNEEKFSLGVEIKTLKEQLNLLSRTEEATKEQVEESG 916
Cdd:pfam02463  883 KLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERN 962

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1039751022  917 AGSSLKLGHDESGQEGLQQELELLRKESEQRKRKLQAALINRKELLQKVSQLEEELAKV 975
Cdd:pfam02463  963 KRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQRLKE 1021
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1269-1713 3.71e-04

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 46.17  E-value: 3.71e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1269 KEELELKVSSIASELAKKSEEVLLLQDQINEQGLEIQNLKAASVEAQAHTELLKQELESSQLKVAGLE-HLKTLQPELDA 1347
Cdd:TIGR04523  220 ISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEkQLNQLKSEISD 299

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1348 LHKhmgQKEEEVN-YLYGQLSEKEQTLTTVQTEMVEQERLIKALHTQLEMQAKEHEERLKQAQVEICELKKKPTELEEET 1426
Cdd:TIGR04523  300 LNN---QKEQDWNkELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLK 376

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1427 NAKQQLQRKLQaALISRKEAL--------KENKSLQEQLSSARDAVERLTKSLADVESQVSVQNQEKDAVLGKLTILQEE 1498
Cdd:TIGR04523  377 KENQSYKQEIK-NLESQINDLeskiqnqeKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELI 455

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1499 RDKLIAEMDRFLLENQSLSGSCESLKLALggltEDKEKLMEELESVRSSKMAESTEWQEKHKELQKEYEVLLQSYENVSN 1578
Cdd:TIGR04523  456 IKNLDNTRESLETQLKVLSRSINKIKQNL----EQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLES 531

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1579 EAERIQHVVESVRQEKQELYAKLRSTESDKREREKQLQDAEQEMEEMKEKMRKfaKSKQQKILELEEENDRLRAEaqpvg 1658
Cdd:TIGR04523  532 EKKEKESKISDLEDELNKDDFELKKENLEKEIDEKNKEIEELKQTQKSLKKKQ--EEKQELIDQKEKEKKDLIKE----- 604

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1039751022 1659 gtgesMEALLSSNSSLKEELEKITLEHKTLSKEFEALMAEKDALSEETRNLKLQV 1713
Cdd:TIGR04523  605 -----IEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETI 654
46 PHA02562
endonuclease subunit; Provisional
 2209-2429 3.79e-04

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 46.16  E-value: 3.79e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2209 HDKEIWESKAQT--ELQHHQKAYDKLQEENKELTSQLEDArqlyhdsKNELTKLESELKSLKDQTTDLNNSLEKCKEHEN 2286
Cdd:PHA02562   200 YNKNIEEQRKKNgeNIARKQNKYDELVEEAKTIKAEIEEL-------TDELLNLVMDIEDPSAALNKLNTAAAKIKSKIE 272

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2287 NLEGIIKQQEaDIQNCKfSCEQletDLAASRELTSRLHDEINAKEQKIISLLSGKEEAIQLAVEELHQQhsKEIKELENL 2366
Cdd:PHA02562   273 QFQKVIKMYE-KGGVCP-TCTQ---QISEGPDRITKIKDKLKELQHSLEKLDTAIDELEEIMDEFNEQS--KKLLELKNK 345

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1039751022 2367 LSQEEEENVALEEENKRALEKTNQLTEALEAIKKESFEQKAQLDSFVKSMSSLQDDRDR--IVSD 2429
Cdd:PHA02562   346 ISTNKQSLITLVDKAKKVKAAIEELQAEFVDNAEELAKLQDELDKIVKTKSELVKEKYHrgIVTD 410
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1280-1449 3.98e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 46.45  E-value: 3.98e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1280 ASELAKKSEEVLLLQDQINEQGLEIQNLKAASVEAQAHTELLKQELES--SQLKVAGLEHLKTLQPELDALHKHMGQKEE 1357
Cdd:COG4913    280 ALRLWFAQRRLELLEAELEELRAELARLEAELERLEARLDALREELDEleAQIRGNGGDRLEQLEREIERLERELEERER 359

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1358 EVNYLYGQLSEKEQTLTTVQTEMVEQERLIKALHTQLEMQAKEHEERLKQAQVEICELKKKPTELEEETNAKQQLQRKLQ 1437
Cdd:COG4913    360 RRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIP 439

                          170
                   ....*....|..
gi 1039751022 1438 AALISRKEALKE 1449
Cdd:COG4913    440 ARLLALRDALAE 451
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2617-2840 4.09e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.53  E-value: 4.09e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2617 SEIEDQLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLTVTKENKDLMAQIQAFGRSMSSLQDSRDHATEE 2696
Cdd:COG4942     19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE 98

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2697 LGDLKKKYDASLKELAQLkewQDSSREGDVLSQAAFplSTSENVLSRLEKLNQQLTSKDEQLLHLSSELESSHNQVQSIS 2776
Cdd:COG4942     99 LEAQKEELAELLRALYRL---GRQPPLALLLSPEDF--LDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAER 173

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1039751022 2777 KAMTSLQNERDRLWSELEKFRKSEEGKQRAAAPSAASSPAEVQSLKKAMSSLQNDRDRLLKELK 2840
Cdd:COG4942    174 AELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAA 237
PTZ00121 PTZ00121
MAEBL; Provisional
 650-1164 4.97e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 46.29  E-value: 4.97e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  650 ERLKTQVLELETSLHTAEETYKrnlSEKVKEISSLTQLSEEVKEsAEEARSTLAAVTEERDQLLYQVKELDVLAELRARV 729
Cdd:PTZ00121  1276 EARKADELKKAEEKKKADEAKK---AEEKKKADEAKKKAEEAKK-ADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAE 1351

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  730 QELESSLAEAEKQRGLDYESQRAQHNLLTEQIHSLSIEAKSKD---VKIEALQRELDGVQlqfceQGTQMKTLQSQLEAK 806
Cdd:PTZ00121  1352 AEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADeakKKAEEDKKKADELK-----KAAAAKKKADEAKKK 1426

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  807 EREVREGTERLRDISQEMEGLSQALSQKELEIAKMDQLLLEKQKDVETLQQTIQEKdQQVTELSFSMTEKMVQLNEEKfs 886
Cdd:PTZ00121  1427 AEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEA-KKADEAKKKAEEAKKKADEAK-- 1503

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  887 lgvEIKTLKEQLNLLSRTEEATK----EQVEESGAGSSLKLGHDESGQEGLQQELEL-----------LRKESEQRKRKL 951
Cdd:PTZ00121  1504 ---KAAEAKKKADEAKKAEEAKKadeaKKAEEAKKADEAKKAEEKKKADELKKAEELkkaeekkkaeeAKKAEEDKNMAL 1580

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  952 QAALINRKELLQKVSQLEEELAKVREDSRKEIPFGENERRKLEEDRENRDDPEEWGTSKWREVEASLKQTISEKEVELEG 1031
Cdd:PTZ00121  1581 RKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENK 1660

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1032 IRRDLKEKTAAEEELQA-VVQRMTRDLQSKTKQIDLLQEEVTENQATIQKLVTGTMDAGNGGSAAPVKETAASSPPGAGG 1110
Cdd:PTZ00121  1661 IKAAEEAKKAEEDKKKAeEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAE 1740

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1039751022 1111 EEHWKPElEGRILDLEKDKTQLQKKLQEaliarKAILKKAQEKEKQLKEELREQ 1164
Cdd:PTZ00121  1741 EDKKKAE-EAKKDEEEKKKIAHLKKEEE-----KKAEEIRKEKEAVIEEELDEE 1788
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1672-1883 5.63e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.14  E-value: 5.63e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1672 SSLKEELEKITLEHKTLSKEFEALMAEKDALSEETRNLKLQVEA--QVLKQASLEATEKSDEPKDVIEEVTQAVVGKSQE 1749
Cdd:COG4942     23 AEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAAlaRRIRALEQELAALEAELAELEKEIAELRAELEAQ 102

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1750 RDALSDSAKledsEAILMGDGAKPGV---SETFSSHDDIKNYLQQL-DQLKGRIAELEMEKQKDRELSQALENEKNALLT 1825
Cdd:COG4942    103 KEELAELLR----ALYRLGRQPPLALllsPEDFLDAVRRLQYLKYLaPARREQAEELRADLAELAALRAELEAERAELEA 178

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1039751022 1826 QISAKDSELKLLEEEVTKRTTLNQQIQEELcrvtKLKETAEEEKDDLEERLMNQLAEL 1883
Cdd:COG4942    179 LLAELEEERAALEALKAERQKLLARLEKEL----AELAAELAELQQEAEELEALIARL 232
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 115-404 5.67e-04

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 45.83  E-value: 5.67e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  115 HELQEKEKLISSLQAQLDQSEQA-----SQLDKSSAEMEDFVLMKQQLQEKE----ELISTLQTQLSQTQAEQAAQLSSM 185
Cdd:TIGR02169  681 ERLEGLKRELSSLQSELRRIENRldelsQELSDASRKIGEIEKEIEQLEQEEeklkERLEELEEDLSSLEQEIENVKSEL 760

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  186 QQVVREKDARFETQVRLHE-------DELLQLVTQSDVETEMQQKLRVMQRK-LEEHEEALLGRAQVVDLLQKELTSAEQ 257
Cdd:TIGR02169  761 KELEARIEELEEDLHKLEEalndleaRLSHSRIPEIQAELSKLEEEVSRIEArLREIEQKLNRLTLEKEYLEKEIQELQE 840

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  258 RNQVLSQQLQLLEAEHNTLKNTMETERQESKTL----------MEKVELEVAERKLSFHNLQEEMHQLQGQLERAGQAQA 327
Cdd:TIGR02169  841 QRIDLKEQIKSIEKEIENLNGKKEELEEELEELeaalrdlesrLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLS 920

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  328 DLETQYSALQQRHKT------EMEEKTACILSL---QKNEQELQSACAALKEENSKL-------------LQEKHDQAAE 385
Cdd:TIGR02169  921 ELKAKLEALEEELSEiedpkgEDEEIPEEELSLedvQAELQRVEEEIRALEPVNMLAiqeyeevlkrldeLKEKRAKLEE 1000

                          330
                   ....*....|....*....
gi 1039751022  386 SAQAMRQLEDQLQQKSKEI 404
Cdd:TIGR02169 1001 ERKAILERIEEYEKKKREV 1019
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 2013-2566 6.86e-04

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 45.60  E-value: 6.86e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2013 LAQAVEHRKKAQAELSSFKILLDDTQSEAARVLADNLKLKKELQSNKESIKSQIKQKDEDLLRRLEQAEEKHRKEKKNMq 2092
Cdd:pfam12128  246 LQQEFNTLESAELRLSHLHFGYKSDETLIASRQEERQETSAELNQLLRTLDDQWKEKRDELNGELSAADAAVAKDRSEL- 324

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2093 EKLDALHR-------EKAHVE-ETLAEIQVSLTRKDQEMKELQGSLDSTLAQLAAFTKSMSS--------LQDDRDRVID 2156
Cdd:pfam12128  325 EALEDQHGafldadiETAAADqEQLPSWQSELENLEERLKALTGKHQDVTAKYNRRRSKIKEqnnrdiagIKDKLAKIRE 404

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2157 EAKKWERRFGDAIQTKEEEVRLKEENCIA-LKDQLRQMAIHMEELKITV------SRLEHDKEIWES---KAQTELQHHQ 2226
Cdd:pfam12128  405 ARDRQLAVAEDDLQALESELREQLEAGKLeFNEEEYRLKSRLGELKLRLnqatatPELLLQLENFDErieRAREEQEAAN 484

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2227 KAYDKLQEENKELTSQLEDARQLYHDSKNELTKLESELKSLKDQ---------------------------------TTD 2273
Cdd:pfam12128  485 AEVERLQSELRQARKRRDQASEALRQASRRLEERQSALDELELQlfpqagtllhflrkeapdweqsigkvispellhRTD 564

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2274 LNNSL-EKCKEHENNLEGI-IKQQEADIQNCKFSCEQLETDLAASRELTSRLHDEINAKEQKiISLLSGKEEAIQLAVEE 2351
Cdd:pfam12128  565 LDPEVwDGSVGGELNLYGVkLDLKRIDVPEWAASEEELRERLDKAEEALQSAREKQAAAEEQ-LVQANGELEKASREETF 643

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2352 LHQQHSKEIKELENLLSQEEEENVALEEENKRALEKTNQLTEALEAikkesfeQKAQLDSFVKSMSSLQDDRDRIVSDYR 2431
Cdd:pfam12128  644 ARTALKNARLDLRRLFDEKQSEKDKKNKALAERKDSANERLNSLEA-------QLKQLDKKHQAWLEEQKEQKREARTEK 716

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2432 QLEERHLSAILEK--DQLIQDAAAENNKLKEEMRGLRSHMD--------------DLNSENAKLDAELVQYRRDLNEVIA 2495
Cdd:pfam12128  717 QAYWQVVEGALDAqlALLKAAIAARRSGAKAELKALETWYKrdlaslgvdpdviaKLKREIRTLERKIERIAVRRQEVLR 796

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1039751022 2496 IKDSQQKQLL---DAQLQQNKELRNECTKLEERLKGLEAE----KQSLQMSSDALQKEKQGLSKEIKNLQTQLTALQE 2566
Cdd:pfam12128  797 YFDWYQETWLqrrPRLATQLSNIERAISELQQQLARLIADtklrRAKLEMERKASEKQQVRLSENLRGLRCEMSKLAT 874
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
2309-2789 7.06e-04

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 45.42  E-value: 7.06e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2309 LETDLAASRELTSRLHDE-INAKEQKiisllsgkeEAIQLAVEElHQQHSKEIKELENLLSQEEEENVALEEENKRALEK 2387
Cdd:PRK02224   211 LESELAELDEEIERYEEQrEQARETR---------DEADEVLEE-HEERREELETLEAEIEDLRETIAETEREREELAEE 280

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2388 TNQLTEALEAIKKESFEQKAQLDSFVKSMSSLQDDRDRIVSDYRQLEERhlsaILEKDQLIQDAAAENNKLKEEMRGLRS 2467
Cdd:PRK02224   281 VRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDR----LEECRVAAQAHNEEAESLREDADDLEE 356

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2468 HMDDLNSENAKLDAELVQYRRDLNEviaikdsqqkqlldaQLQQNKELRNECTKLEERLKGLEAEKQSLQMSSDALQKEK 2547
Cdd:PRK02224   357 RAEELREEAAELESELEEAREAVED---------------RREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREER 421

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2548 QGLSKEIKNLQTQLT----------ALQEEG--------------------------TLGVYHAQLKAKEEEL-QRLNMA 2590
Cdd:PRK02224   422 DELREREAELEATLRtarerveeaeALLEAGkcpecgqpvegsphvetieedrerveELEAELEDLEEEVEEVeERLERA 501

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2591 --LSSSQKRTADLEE------ELVCVQKEATRKVSEIEDQLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKL 2662
Cdd:PRK02224   502 edLVEAEDRIERLEErredleELIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKL 581

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2663 LTVTKEN------KDLMAQIQAFGRSMSSLQDSRDHATeELGDLKKKYdasLKELAQLKEWQDSSREGDVLSQAAFPLST 2736
Cdd:PRK02224   582 AELKERIesleriRTLLAAIADAEDEIERLREKREALA-ELNDERRER---LAEKRERKRELEAEFDEARIEEAREDKER 657

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1039751022 2737 SENVLSRLEKLNQQLTSKDEQLLHLSSELESSHNQVQSISKAMTSLQNERDRL 2789
Cdd:PRK02224   658 AEEYLEQVEEKLDELREERDDLQAEIGAVENELEELEELRERREALENRVEAL 710
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1546-2005 7.26e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 45.14  E-value: 7.26e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1546 SSKMAESTEWQEKHKELQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQ--ELYAKLRSTESDKREREKQLQDAEQEME 1623
Cdd:COG4717     77 EEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQllPLYQELEALEAELAELPERLEELEERLE 156

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1624 EMkekmrkfaKSKQQKILELEEENDRLRAEAQpvggtgesmEALLSSNSSLKEELEKITLEHKTLSKEFEALMAEKDALS 1703
Cdd:COG4717    157 EL--------RELEEELEELEAELAELQEELE---------ELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQ 219

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1704 EETRNLKLQVEAQVLKQASLEATEKSDEPKDVIEEVTQAVVGKSQERDALSDSAKLEDSEAILMGDGAkPGVSETFSSHD 1783
Cdd:COG4717    220 EELEELEEELEQLENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLA-LLFLLLAREKA 298

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1784 DIKNYLQQLDQLKGRIAELEMEKQKDRELSQALENEKNALLTQISAKDSELKLLEEEVTKRTTLNQQIQEELCRVTKLKE 1863
Cdd:COG4717    299 SLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQEIAALLAE 378

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1864 TAEEEKDDLEERLM---------NQLAELNGSIGNYYQDVTD--AQIKNEQLESEMRNLQRCVSELEEEKQQLVKEKTKV 1932
Cdd:COG4717    379 AGVEDEEELRAALEqaeeyqelkEELEELEEQLEELLGELEEllEALDEEELEEELEELEEELEELEEELEELREELAEL 458

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1039751022 1933 ESEIRkeymekiqgaqkgpaNKSHAKELQELLREKQQEVKQLQkdciRYLERISALEKTVKALEFVHTESQKD 2005
Cdd:COG4717    459 EAELE---------------QLEEDGELAELLQELEELKAELR----ELAEEWAALKLALELLEEAREEYREE 512
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1897-2351 7.36e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 45.29  E-value: 7.36e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1897 AQIKNEQLESEMRNLQRCVSELEEEKQQLVKEKTKVESEIRkEYMEKIQGAQkgpankshAKELQELlrekQQEVKQLQK 1976
Cdd:COG4913    286 AQRRLELLEAELEELRAELARLEAELERLEARLDALREELD-ELEAQIRGNG--------GDRLEQL----EREIERLER 352

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1977 DCIRYLERISALEKTVKALEFVHTESQKDLdvtKGNLAQAVEHRKKAQAELSSfkilLDDTQSEAARVLADNLKLKKELQ 2056
Cdd:COG4913    353 ELEERERRRARLEALLAALGLPLPASAEEF---AALRAEAAALLEALEEELEA----LEEALAEAEAALRDLRRELRELE 425

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2057 SNKESI---KSQIKQKDEDLLRRLEQA-----------------------------------------EEKHRK------ 2086
Cdd:COG4913    426 AEIASLerrKSNIPARLLALRDALAEAlgldeaelpfvgelievrpeeerwrgaiervlggfaltllvPPEHYAaalrwv 505

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2087 EKKNMQEKLDALHREKAHVEETLAEIQV-SLTRK-DQEMKELQGSLDSTLAQLAAFTK--SMSSLQDDRDRV-------- 2154
Cdd:COG4913    506 NRLHLRGRLVYERVRTGLPDPERPRLDPdSLAGKlDFKPHPFRAWLEAELGRRFDYVCvdSPEELRRHPRAItragqvkg 585

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2155 ------IDEAKKWERR--FG----DAIQTKEEEVRLKEENCIALKDQLRQMAIHMEELKITVSRLEHDKEIWESK----- 2217
Cdd:COG4913    586 ngtrheKDDRRRIRSRyvLGfdnrAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEidvas 665

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2218 AQTELQHHQKAYDKLQEEN---KELTSQLEDARQLYHDSKNELTKLESELKSLKDQTTDLNNSLEKCKEHENNLEGIIKQ 2294
Cdd:COG4913    666 AEREIAELEAELERLDASSddlAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARL 745

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1039751022 2295 QEAdiqnckfscEQLETDLAA--SRELTSRLHDEINAKEQKIISLLSGKEEAIQLAVEE 2351
Cdd:COG4913    746 ELR---------ALLEERFAAalGDAVERELRENLEERIDALRARLNRAEEELERAMRA 795
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1350-1887 8.16e-04

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 45.44  E-value: 8.16e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1350 KHMGQKEEEVNYLYGQLSEKEQTLTTVQTEMVEQERL------IKALHTQLEMQAKEHEERLKQAQVEICELKKKPTELE 1423
Cdd:PRK03918   200 KELEEVLREINEISSELPELREELEKLEKEVKELEELkeeieeLEKELESLEGSKRKLEEKIRELEERIEELKKEIEELE 279

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1424 E------ETNAKQQLQRKLQAALISRKEALKENKSLQEQLSSARDAVERLTKSLADVESQVSVQNQEKDAVLGKLTILqE 1497
Cdd:PRK03918   280 EkvkelkELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEEL-E 358

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1498 ERDKLIAEMDRFLLENQSLSG-----SCESLKLALGGLTEDKEKLMEELESVRsskmAESTEWQEKHKELQKEYEVL--- 1569
Cdd:PRK03918   359 ERHELYEEAKAKKEELERLKKrltglTPEKLEKELEELEKAKEEIEEEISKIT----ARIGELKKEIKELKKAIEELkka 434

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1570 ---------LQSYENVSNEAERIQHVVESVRQEKQELYAKLRSTESDKREREKQLQDAEQEMEEMKEKMRKFAKSKQQKI 1640
Cdd:PRK03918   435 kgkcpvcgrELTEEHRKELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKLKELAEQLKELEEKLKK 514

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1641 LELEEendrLRAEAQPVGGTGESMEALLSSNSSLKEELEKItlehKTLSKEFEALMAEKDALSEETRNLKLQVEAQVLKQ 1720
Cdd:PRK03918   515 YNLEE----LEKKAEEYEKLKEKLIKLKGEIKSLKKELEKL----EELKKKLAELEKKLDELEEELAELLKELEELGFES 586

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1721 ASlEATEKSDEPKDVIEEVTQAVVGKSQERDALSDSAKLEDSEailmgDGAKPGVSETFSSHDDIKNYLQQLDQL--KGR 1798
Cdd:PRK03918   587 VE-ELEERLKELEPFYNEYLELKDAEKELEREEKELKKLEEEL-----DKAFEELAETEKRLEELRKELEELEKKysEEE 660

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1799 IAELEMEKQKDRELSQALENEKNALLTQISAKDSELKLLEEEVTKRTTLNQQIQ---EELCRVTKLKETAEEEKDDLEER 1875
Cdd:PRK03918   661 YEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKAKKELEkleKALERVEELREKVKKYKALLKER 740

                          570
                   ....*....|..
gi 1039751022 1876 LMNQLAELNGSI 1887
Cdd:PRK03918   741 ALSKVGEIASEI 752
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1366-2138 8.29e-04

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 45.49  E-value: 8.29e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1366 LSEKEQTLTTVQTEMVEQERLIKALHTQLEMQAKEHEERLKQAQVE---ICELKKKPTELEEE-TNAKQQLQRKLQAALI 1441
Cdd:pfam15921   80 LEEYSHQVKDLQRRLNESNELHEKQKFYLRQSVIDLQTKLQEMQMErdaMADIRRRESQSQEDlRNQLQNTVHELEAAKC 159

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1442 SRKEALKENKSLQEQLS----SARDAVERLTKSLADVESQVSVQNQEKDAVLG-KLTILQEERDKLIAEMDR-------- 1508
Cdd:pfam15921  160 LKEDMLEDSNTQIEQLRkmmlSHEGVLQEIRSILVDFEEASGKKIYEHDSMSTmHFRSLGSAISKILRELDTeisylkgr 239

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1509 -FLLENQSLSGSCES---LKLALGGLTEDKEKLMEELESVRSSKMAESTEWQEKHKELQKEYEVLLQSYENVSNEAERIQ 1584
Cdd:pfam15921  240 iFPVEDQLEALKSESqnkIELLLQQHQDRIEQLISEHEVEITGLTEKASSARSQANSIQSQLEIIQEQARNQNSMYMRQL 319

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1585 HVVES-VRQEKQELYAKLRSTESDKREREKQLQDAeqemeemkekmrkfakskQQKILELEEENDRLRAEAqpvGGTGES 1663
Cdd:pfam15921  320 SDLEStVSQLRSELREAKRMYEDKIEELEKQLVLA------------------NSELTEARTERDQFSQES---GNLDDQ 378

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1664 MEALLSSNSSLKEELekitlehkTLSKEFEALMAEKDALSEET-RNLKLQVEAQVLKQASLEATEKS--DEPKDVIEEVT 1740
Cdd:pfam15921  379 LQKLLADLHKREKEL--------SLEKEQNKRLWDRDTGNSITiDHLRRELDDRNMEVQRLEALLKAmkSECQGQMERQM 450

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1741 QAVVGKSQERDALSD-SAKLEDSEAILMGdgakpgVSETFSSHDdiknylQQLDQLKGRIAELEMEKQKDRELSQALENE 1819
Cdd:pfam15921  451 AAIQGKNESLEKVSSlTAQLESTKEMLRK------VVEELTAKK------MTLESSERTVSDLTASLQEKERAIEATNAE 518

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1820 KNALLTQISAKDSELKLLEEEVTKRttlnQQIQEElCRVTKLKETaeeEKDDLEERLMNQLAELNGSIGNYYQDVTDAQI 1899
Cdd:pfam15921  519 ITKLRSRVDLKLQELQHLKNEGDHL----RNVQTE-CEALKLQMA---EKDKVIEILRQQIENMTQLVGQHGRTAGAMQV 590

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1900 KNEQLESEMRNLQRCVSELEEEKQQLVKEKTKVESEIRKEYMEKIQGAQKGpankshaKELQELLREKQQEVKQLQKDCI 1979
Cdd:pfam15921  591 EKAQLEKEINDRRLELQEFKILKDKKDAKIRELEARVSDLELEKVKLVNAG-------SERLRAVKDIKQERDQLLNEVK 663

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1980 RYLERISALEKTVKALEFVHTESQKDLDVTKGNLAQAVehrKKAQAELSSFKILLDDTQSEAARVLADNLKLKKELQSNK 2059
Cdd:pfam15921  664 TSRNELNSLSEDYEVLKRNFRNKSEEMETTTNKLKMQL---KSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQKQITAKR 740

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2060 ESIKSqIKQKDEDLLRRLEQA-EEKH--RKEKKNMQEKLDALHREKAHVEETLAEIQVSLTRKDQEMKELQGSLDSTLAQ 2136
Cdd:pfam15921  741 GQIDA-LQSKIQFLEEAMTNAnKEKHflKEEKNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANMEVALDKASLQ 819


                   ..
gi 1039751022 2137 LA 2138
Cdd:pfam15921  820 FA 821
MAD pfam05557
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ...
 1791-2280 8.49e-04

Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.


Pssm-ID: 461677 [Multi-domain]  Cd Length: 660  Bit Score: 45.12  E-value: 8.49e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1791 QLDQLKGRIAELEMEKQKDRELSQALENEKNALLTQISAKDSELKLLEEEVTKRTTLNQQIQEELCRVTKLKETAEEEKD 1870
Cdd:pfam05557   10 RLSQLQNEKKQMELEHKRARIELEKKASALKRQLDRESDRNQELQKRIRLLEKREAEAEEALREQAELNRLKKKYLEALN 89

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1871 DLEERLMNQLAELNGSIGNYYQDVTDAQIKNEQLESEmrnLQRCVSELEEEKQQLVKEKTKVEseirkEYMEKIQGAQKG 1950
Cdd:pfam05557   90 KKLNEKESQLADAREVISCLKNELSELRRQIQRAELE---LQSTNSELEELQERLDLLKAKAS-----EAEQLRQNLEKQ 161

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1951 P-ANKSHAKELQELLREKQQEV--KQLQKDCIRYLERISALEKTVKALEfvhtESQKDLDVTKGNLAQAVEHRKKAQAEL 2027
Cdd:pfam05557  162 QsSLAEAEQRIKELEFEIQSQEqdSEIVKNSKSELARIPELEKELERLR----EHNKHLNENIENKLLLKEEVEDLKRKL 237

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2028 SSFkillDDTQSEAARVLADNLKLKKELQSNKESIKSQIKQ--KDEDLLRRLEQAEekhrKEKKNMQEKLDALHREKAHV 2105
Cdd:pfam05557  238 ERE----EKYREEAATLELEKEKLEQELQSWVKLAQDTGLNlrSPEDLSRRIEQLQ----QREIVLKEENSSLTSSARQL 309

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2106 EETLAEIQVSLTRKDQEMKELQGSLDSTLAQLAAFTKSMSSLQDDRDRVIDEAKKWerrfgDAIQTKEEEVRLKEENCIA 2185
Cdd:pfam05557  310 EKARRELEQELAQYLKKIEDLNKKLKRHKALVRRLQRRVLLLTKERDGYRAILESY-----DKELTMSNYSPQLLERIEE 384

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2186 LKDQLRQMAIHMEELKITVSRLEHDKEIWESKAQTELQHHQKAydKLQEENKELTSQLEDARQLYHdsknELTKLESELK 2265
Cdd:pfam05557  385 AEDMTQKMQAHNEEMEAQLSVAEEELGGYKQQAQTLERELQAL--RQQESLADPSYSKEEVDSLRR----KLETLELERQ 458

                          490
                   ....*....|....*
gi 1039751022 2266 SLKDQTTDLNNSLEK 2280
Cdd:pfam05557  459 RLREQKNELEMELER 473
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1334-2147 8.50e-04

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 45.11  E-value: 8.50e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1334 GLEHLKTLQPELDALHKHMGQKEEEVNYLY-GQLSEKEQTLTTVQTEMVEQERLIKALHTQLEMQAKEHEERLKQAQVEI 1412
Cdd:pfam15921   72 GKEHIERVLEEYSHQVKDLQRRLNESNELHeKQKFYLRQSVIDLQTKLQEMQMERDAMADIRRRESQSQEDLRNQLQNTV 151

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1413 CELKKKPTELEEETNAKQQLQRKLQAALISRKEALKENKSLQEQLSSARDaverltKSLADVESQVSVQNQEKDAVLGKl 1492
Cdd:pfam15921  152 HELEAAKCLKEDMLEDSNTQIEQLRKMMLSHEGVLQEIRSILVDFEEASG------KKIYEHDSMSTMHFRSLGSAISK- 224

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1493 tILQEERDKLIAEMDR-FLLENQSLSGSCES---LKLALGGLTEDKEKLMEELESVRSSKMAESTEWQEKHKELQKEYEV 1568
Cdd:pfam15921  225 -ILRELDTEISYLKGRiFPVEDQLEALKSESqnkIELLLQQHQDRIEQLISEHEVEITGLTEKASSARSQANSIQSQLEI 303

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1569 LLQSYENVSNEAERIQHVVES-VRQEKQELYAKLRSTESDKREREKQLQDAEQEMEEMKEKMRKFAKS------------ 1635
Cdd:pfam15921  304 IQEQARNQNSMYMRQLSDLEStVSQLRSELREAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQEsgnlddqlqkll 383

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1636 ----KQQKILELEEENDRLRAEAQpvggTGESMeallsSNSSLKEELEKITLEHKTLSKEFEALMAEKDALSEETRNLKL 1711
Cdd:pfam15921  384 adlhKREKELSLEKEQNKRLWDRD----TGNSI-----TIDHLRRELDDRNMEVQRLEALLKAMKSECQGQMERQMAAIQ 454

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1712 QVEAQVLKQASLEATEKSDEP--KDVIEEVT-QAVVGKSQERDALSDSAKLEDSEAILMGDGAKpgvSETFSSHDDIKny 1788
Cdd:pfam15921  455 GKNESLEKVSSLTAQLESTKEmlRKVVEELTaKKMTLESSERTVSDLTASLQEKERAIEATNAE---ITKLRSRVDLK-- 529

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1789 LQQLDQLKGRIAELemekqkdrelsQALENEKNALLTQISAKDSELKLLEEEVTKRTTLNQQiqeelcrVTKLKETAEEE 1868
Cdd:pfam15921  530 LQELQHLKNEGDHL-----------RNVQTECEALKLQMAEKDKVIEILRQQIENMTQLVGQ-------HGRTAGAMQVE 591

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1869 KDDLEERLMNQLAELNgsignyyqdvtDAQIKNEQLESEMRNLQRCVSELEEEKQQLV---KEKTKVESEIRKEYMEKIQ 1945
Cdd:pfam15921  592 KAQLEKEINDRRLELQ-----------EFKILKDKKDAKIRELEARVSDLELEKVKLVnagSERLRAVKDIKQERDQLLN 660

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1946 GAQKGPANKSHAKELQELL----REKQQEVKQLQKDCIRYLERI-SALEKTVKALEFVHTESQKDLDVTKGNLAQAVEHR 2020
Cdd:pfam15921  661 EVKTSRNELNSLSEDYEVLkrnfRNKSEEMETTTNKLKMQLKSAqSELEQTRNTLKSMEGSDGHAMKVAMGMQKQITAKR 740

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2021 KKAQAELSSFKILLDDTQSeaARVLADNLKLKKELQSNKESIKSQIKQKDEDLLRRLEQAEEKHRKEKKNMQEKLDalhr 2100
Cdd:pfam15921  741 GQIDALQSKIQFLEEAMTN--ANKEKHFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANMEVALD---- 814

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1039751022 2101 eKAHVEetLAEIQVSLTRKDQE-----------MKELQG-------SLDSTLAQLAAFTKSMSSL 2147
Cdd:pfam15921  815 -KASLQ--FAECQDIIQRQEQEsvrlklqhtldVKELQGpgytsnsSMKPRLLQPASFTRTHSNV 876
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
672-1084 1.11e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 44.76  E-value: 1.11e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  672 RNLSEKVKEISSLTQLSEEVKESAEEARSTLAAVTEERDQLLYQVKELDVLAELRARVQELESSLAEAE--KQRGLDYES 749
Cdd:COG4717     81 KEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEALEAELAELPERLEelEERLEELRE 160

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  750 QRAQHNLLTEQIHSLSIEAKskdvkiEALQRELDGVQLQFCEQGTQMKTLQSQLEAKEREVREGTERLRDISQEMEGLSQ 829
Cdd:COG4717    161 LEEELEELEAELAELQEELE------ELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLEN 234

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  830 ALS----QKELEIAKMDQLLLEKQKDVETLQQTIQEKDQQVTELSFSMTEKMV----QLNEEKFSLGVEIKTLKEQLNLL 901
Cdd:COG4717    235 ELEaaalEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLAllflLLAREKASLGKEAEELQALPALE 314

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  902 SRTEEATKEQVEESGAGSSLKLGHDESGQEGLQQELELLRK-ESEQRKRKLQAALINRKELLQKVSQLEEELAKVREDSR 980
Cdd:COG4717    315 ELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREaEELEEELQLEELEQEIAALLAEAGVEDEEELRAALEQA 394

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  981 KEIPFGENERRKLEEDRENRDDPEEWGTSKWreVEASLKQTISEKEVELEGIRRDLKEKTAAEEELQAVVQRMTRD--LQ 1058
Cdd:COG4717    395 EEYQELKEELEELEEQLEELLGELEELLEAL--DEEELEEELEELEEELEELEEELEELREELAELEAELEQLEEDgeLA 472

                          410       420
                   ....*....|....*....|....*.
gi 1039751022 1059 SKTKQIDLLQEEVTENQATIQKLVTG 1084
Cdd:COG4717    473 ELLQELEELKAELRELAEEWAALKLA 498
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 1864-2111 1.14e-03

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 44.53  E-value: 1.14e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1864 TAEEEKDDLEERLMN----QLAELNGSIGNYYqdvtdaqikNEQLESEMRNLQRCVSELEEEKQqlvKEKTKVESEIRKE 1939
Cdd:PRK05771    13 TLKSYKDEVLEALHElgvvHIEDLKEELSNER---------LRKLRSLLTKLSEALDKLRSYLP---KLNPLREEKKKVS 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1940 YMEKIQGAQKGPANKShakELQELLREKQQEVKQLQkdcirylERISALEKTVKALEFVhtesqKDLDV------TKGNL 2013
Cdd:PRK05771    81 VKSLEELIKDVEEELE---KIEKEIKELEEEISELE-------NEIKELEQEIERLEPW-----GNFDLdlslllGFKYV 145

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2014 AQAVEHRKKAQAELSS--------------------FKILLDDTQSEAARVLADNLKLKKELQ---------SNKESIKS 2064
Cdd:PRK05771   146 SVFVGTVPEDKLEELKlesdvenveyistdkgyvyvVVVVLKELSDEVEEELKKLGFERLELEeegtpseliREIKEELE 225

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*..
gi 1039751022 2065 QIKQKDEDLLRRLEQAEEKHRKEKKNMQEKLDALhREKAHVEETLAE 2111
Cdd:PRK05771   226 EIEKERESLLEELKELAKKYLEELLALYEYLEIE-LERAEALSKFLK 271
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 667-1073 1.37e-03

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 44.33  E-value: 1.37e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  667 EETYKRNLSEKVKEISSLTQLSEEVKESAEEARSTLAAVTEERDQLLYQVK-ELDVLAELRARVQELESSLAEAEKQRGL 745
Cdd:pfam05483  228 EEEYKKEINDKEKQVSLLLIQITEKENKMKDLTFLLEESRDKANQLEEKTKlQDENLKELIEKKDHLTKELEDIKMSLQR 307

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  746 DYESQRAQHNLLTEQIHSLSIEAKSKDVKIEALQRE-------LDGVQLQFCEQGTQMKTLQSQLEAKEREVREGTERLR 818
Cdd:pfam05483  308 SMSTQKALEEDLQIATKTICQLTEEKEAQMEELNKAkaahsfvVTEFEATTCSLEELLRTEQQRLEKNEDQLKIITMELQ 387

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  819 DISQEMEGLSQALSQKELEIAKM------DQLLLEKQKDVETLQQTIQEKDQQVTELSFSMTEKMVQLNEEKFSLGV-EI 891
Cdd:pfam05483  388 KKSSELEEMTKFKNNKEVELEELkkilaeDEKLLDEKKQFEKIAEELKGKEQELIFLLQAREKEIHDLEIQLTAIKTsEE 467

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  892 KTLKEQLNLLSRTEEATKEQVEESGAGSSLKLGHDESGQEGLQQELELLRKESE--QRKRKLQAALINRKELLQKVSQLE 969
Cdd:pfam05483  468 HYLKEVEDLKTELEKEKLKNIELTAHCDKLLLENKELTQEASDMTLELKKHQEDiiNCKKQEERMLKQIENLEEKEMNLR 547

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  970 EELAKVREDSRKEipfGENERRKLEEDRENRDDPEEWGTSKWREVEASlkqtisekEVELEGIRRDLKEKTAAEEELQAV 1049
Cdd:pfam05483  548 DELESVREEFIQK---GDEVKCKLDKSEENARSIEYEVLKKEKQMKIL--------ENKCNNLKKQIENKNKNIEELHQE 616

                          410       420
                   ....*....|....*....|....
gi 1039751022 1050 VQRMTRDLQSKTKQIDLLQEEVTE 1073
Cdd:pfam05483  617 NKALKKKGSAENKQLNAYEIKVNK 640
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 652-1073 1.39e-03

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 44.24  E-value: 1.39e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  652 LKTQVLELE---TSLHTAEETYKRNLSEKVKEISSLTQLSEEVKESAEEARSTLAAVTEERDQLLYQVKELDvlaelrAR 728
Cdd:TIGR04523  216 LESQISELKkqnNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELE------KQ 289

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  729 VQELESSLAEAEKQRGLDYESQ-RAQHNLLTEQIHSLSIEAKSKDVKIEALQRELDGVQLQFCEQGTQMKTLQSQLEAKE 807
Cdd:TIGR04523  290 LNQLKSEISDLNNQKEQDWNKElKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQ 369

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  808 REVREGTERLRDISQEMEGLSQALSQKELEIAKMDQLLLEKQKDVETLQQTIQEKDQQVTELSfsmtEKMVQLNEEKFSL 887
Cdd:TIGR04523  370 NEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLK----ETIIKNNSEIKDL 445

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  888 GVEIKTLKEQLNLLSRTEEATKEQVEESgagsslklghdESGQEGLQQELELLRKESEQRKRKLQAALINRKELLQKVSQ 967
Cdd:TIGR04523  446 TNQDSVKELIIKNLDNTRESLETQLKVL-----------SRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKD 514

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  968 LEEELAKVREDSRKEipfgenERRKLEEDRENRDDPEEWGTSKWREVEASLKQTISEKEVELEGIRRDLKEKTAAEEELQ 1047
Cdd:TIGR04523  515 LTKKISSLKEKIEKL------ESEKKEKESKISDLEDELNKDDFELKKENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQ 588

                          410       420
                   ....*....|....*....|....*.
gi 1039751022 1048 AVVQRMTRDLQSKTKQIDLLQEEVTE 1073
Cdd:TIGR04523  589 ELIDQKEKEKKDLIKEIEEKEKKISS 614
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 794-998 1.40e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 44.05  E-value: 1.40e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  794 TQMKTLQSQLEAKEREVREGTERLRDISQEMEGLSQALSQKELEIAKMDQLLLEKQKDVETLQQTIQEKDQQVTELSFSM 873
Cdd:COG3883     16 PQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARAL 95

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  874 TEKMVQLNEEKFSLGVE-IKTLKEQLNLLSRTEEATKEQVEESGAgSSLKLGHDESGQEGLQQELELLRKESEQRKRKLQ 952
Cdd:COG3883     96 YRSGGSVSYLDVLLGSEsFSDFLDRLSALSKIADADADLLEELKA-DKAELEAKKAELEAKLAELEALKAELEAAKAELE 174

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*.
gi 1039751022  953 AALINRKELLQKVSQLEEELAKVREDSRKEIPFGENERRKLEEDRE 998
Cdd:COG3883    175 AQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAA 220
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 647-1203 1.41e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 44.67  E-value: 1.41e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  647 GELERLKTQVLELETSLHTAE---ETYKRNLSEKVKEISSLTQLSEEVKESAEEARSTLAAVTEERDQLLYQVKEL-DVL 722
Cdd:TIGR02169  287 EEQLRVKEKIGELEAEIASLErsiAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELkEEL 366

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  723 AELRARVQELESSLAE-----AEKQRGLD------YESQRAQHNL------LTEQIHSLSIEAKSKDVKIEALQRELDGV 785
Cdd:TIGR02169  367 EDLRAELEEVDKEFAEtrdelKDYREKLEklkreiNELKRELDRLqeelqrLSEELADLNAAIAGIEAKINELEEEKEDK 446

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  786 QLQFCEQGTQMKTLQSQLEAKEREVREGTERLRDISQEMEGLSQALSQKE------------------------------ 835
Cdd:TIGR02169  447 ALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEaqaraseervrggraveevlkasiqgvhgt 526

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  836 --------------LEIAKMDQLLLEKQKDVETLQQTIQ-EKDQQVTELSFSMTEKMVQLNEEKfSLGVEIKTLKEQLNL 900
Cdd:TIGR02169  527 vaqlgsvgeryataIEVAAGNRLNNVVVEDDAVAKEAIElLKRRKAGRATFLPLNKMRDERRDL-SILSEDGVIGFAVDL 605

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  901 L--------------------SRTEEATK------------EQVEESGA--GSSLKLGHDESGQ--------------EG 932
Cdd:TIGR02169  606 VefdpkyepafkyvfgdtlvvEDIEAARRlmgkyrmvtlegELFEKSGAmtGGSRAPRGGILFSrsepaelqrlrerlEG 685

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  933 LQQELELLRKESEQRKRKLQAALINRKELLQKVSQLEEELAKVREDSRKEIPFGENERRKLEEdrenrddpeewgtskwr 1012
Cdd:TIGR02169  686 LKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSS----------------- 748

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1013 eveasLKQTISEKEVELEGIRRDLKEKTAAEEELQAVVQRMTRDL-----QSKTKQIDLLQEEVTENQATIQKLVTGTmd 1087
Cdd:TIGR02169  749 -----LEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLshsriPEIQAELSKLEEEVSRIEARLREIEQKL-- 821

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1088 agngGSAAPVKETAASSppgaggeehwKPELEGRILDLEKDKTQLQKKlQEALIARKAilkKAQEKEKQLKEELREQKDA 1167
Cdd:TIGR02169  822 ----NRLTLEKEYLEKE----------IQELQEQRIDLKEQIKSIEKE-IENLNGKKE---ELEEELEELEAALRDLESR 883

                          650       660       670
                   ....*....|....*....|....*....|....*.
gi 1039751022 1168 YHHLQGQFHEQNKEKENIADQLRQLQCQARESIDRQ 1203
Cdd:TIGR02169  884 LGDLKKERDELEAQLRELERKIEELEAQIEKKRKRL 919
PRK11281 PRK11281
mechanosensitive channel MscK;
116-337 1.42e-03

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 44.52  E-value: 1.42e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  116 ELQEKEKLISSLQAQLDQSEQASQLDKSSAEMEDFVLMKQ-QLQEKEE-------LISTLQTQLSQTQAEQAAQLSSMQQ 187
Cdd:PRK11281    95 KLRQAQAELEALKDDNDEETRETLSTLSLRQLESRLAQTLdQLQNAQNdlaeynsQLVSLQTQPERAQAALYANSQRLQQ 174

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  188 VVREKDARFETQVRLHEDELLQLVTQS---DVETEMQQKL----RVMQRKLEEHEEALLGRAQV----VDLLQ-----KE 251
Cdd:PRK11281   175 IRNLLKGGKVGGKALRPSQRVLLQAEQallNAQNDLQRKSlegnTQLQDLLQKQRDYLTARIQRlehqLQLLQeainsKR 254

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  252 LTSAEQRNQVLSQQLQLLEAEHNTL-KNTMETERQESKTLMEKVELEVAerkLSFHNLQeemhqLQGQLERAGQAQADLE 330
Cdd:PRK11281   255 LTLSEKTVQEAQSQDEAARIQANPLvAQELEINLQLSQRLLKATEKLNT---LTQQNLR-----VKNWLDRLTQSERNIK 326


                   ....*..
gi 1039751022  331 TQYSALQ 337
Cdd:PRK11281   327 EQISVLK 333
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1016-1221 1.48e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.98  E-value: 1.48e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1016 ASLKQTISEKEVELEGIRRDLKEKTAAEEELQAVVQRMTRDLQSKTKQIDLLQEEVTENQATIQKLVTGTMDAGNGGSAA 1095
Cdd:COG4942     44 AALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELAELLRALYRLGRQPPLA 123

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1096 PVkeTAASSPPGAGGEEHW----KPELEGRILDLEKDKTQLQKKLQEALIARK---AILKKAQEKEKQLKEELREQKDAY 1168
Cdd:COG4942    124 LL--LSPEDFLDAVRRLQYlkylAPARREQAEELRADLAELAALRAELEAERAeleALLAELEEERAALEALKAERQKLL 201

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1039751022 1169 HHLQGQFHEQNKEKENIADQLRQLQcQARESIDRQLPGTGQQEPGPPAPSLEG 1221
Cdd:COG4942    202 ARLEKELAELAAELAELQQEAEELE-ALIARLEAEAAAAAERTPAAGFAALKG 253
PRK12704 PRK12704
phosphodiesterase; Provisional
 1129-1204 1.52e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 44.00  E-value: 1.52e-03
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1039751022 1129 KTQLQKKLQEALIARKAILKKAQEKEKQLKEE-LREQKDAYHHLQGQFHEQNKEKEN-IADQLRQLQcQARESIDRQL 1204
Cdd:PRK12704    26 KKIAEAKIKEAEEEAKRILEEAKKEAEAIKKEaLLEAKEEIHKLRNEFEKELRERRNeLQKLEKRLL-QKEENLDRKL 102
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1338-1721 1.58e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 43.99  E-value: 1.58e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1338 LKTLQPELDALHKHMGQK---------------------EEEVNYLYGQLSEKEQTLTTVQTEMVEQERLIKALHT---- 1392
Cdd:COG4717     48 LERLEKEADELFKPQGRKpelnlkelkeleeelkeaeekEEEYAELQEELEELEEELEELEAELEELREELEKLEKllql 127

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1393 --------QLEMQAKEHEERLKQAQVEICELKKKPTELEEETNAKQQLQRKLQAALISRKEALKEN-KSLQEQLSSARDA 1463
Cdd:COG4717    128 lplyqeleALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEElQDLAEELEELQQR 207

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1464 VERLTKSLADVESQVSVQNQEKDAVLGKLTILQEERDKLIAEMDRF----LLENQSLSGSCESLKLALGGL--------- 1530
Cdd:COG4717    208 LAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLLLLiaaaLLALLGLGGSLLSLILTIAGVlflvlglla 287

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1531 ---------TEDKEKLMEELESVRSSKMAESTEWQEKHKELQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQELyakl 1601
Cdd:COG4717    288 llflllareKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEEL---- 363

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1602 rSTESDKREREKQLQDAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEAqpvggTGESMEALLSSNSSLKEELEKI 1681
Cdd:COG4717    364 -QLEELEQEIAALLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELL-----GELEELLEALDEEELEEELEEL 437

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|
gi 1039751022 1682 TLEHKTLSKEFEALMAEKDALSEETRNLKLQVEAQVLKQA 1721
Cdd:COG4717    438 EEELEELEEELEELREELAELEAELEQLEEDGELAELLQE 477
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 2576-3019 1.61e-03

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 44.44  E-value: 1.61e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2576 QLKAKEEELQRLNMALSSSQKRTADLEEELVCVQKEATRKVSEIEDQLKKELKHLHHDAGIMRNETETAEERVAELARDL 2655
Cdd:pfam12128  252 TLESAELRLSHLHFGYKSDETLIASRQEERQETSAELNQLLRTLDDQWKEKRDELNGELSAADAAVAKDRSELEALEDQH 331

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2656 VEMEQKLLTVTKENKDLMAQIQAfgrSMSSLQDSRDHATEELGDLKKKYDA--------SLKELAQLKEWQDSSREGDVL 2727
Cdd:pfam12128  332 GAFLDADIETAAADQEQLPSWQS---ELENLEERLKALTGKHQDVTAKYNRrrskikeqNNRDIAGIKDKLAKIREARDR 408

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2728 SQAAfplstSENVLSRLE-----KLNQQLTSKDEQLLHLSS---ELESSHNQVQSISKAMTSLQNERDRL---WSELEKF 2796
Cdd:pfam12128  409 QLAV-----AEDDLQALEselreQLEAGKLEFNEEEYRLKSrlgELKLRLNQATATPELLLQLENFDERIeraREEQEAA 483

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2797 RKSEEGKQRAAAPSAASSPAEVQSLKKAMSSLQNDRDRllkeLKNLQQQYLQMSQEMTELRPLKAQLQEsQDQTKAL--- 2873
Cdd:pfam12128  484 NAEVERLQSELRQARKRRDQASEALRQASRRLEERQSA----LDELELQLFPQAGTLLHFLRKEAPDWE-QSIGKVIspe 558

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2874 ---------QVMEEELRQENLSWQHELRQLRMEKNSWELHERRMKE---QFLMAISDKDQQLGHLQSLLRELRSSSQAQI 2941
Cdd:pfam12128  559 llhrtdldpEVWDGSVGGELNLYGVKLDLKRIDVPEWAASEEELRErldKAEEALQSAREKQAAAEEQLVQANGELEKAS 638

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1039751022 2942 LSTQYQRQASPETSASLdgsQKLVYETELLRTQLNDSLKEihqkelRIQQLNSKFSQLLEEKNVLSTQLSDASQSLRE 3019
Cdd:pfam12128  639 REETFARTALKNARLDL---RRLFDEKQSEKDKKNKALAE------RKDSANERLNSLEAQLKQLDKKHQAWLEEQKE 707
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 1790-1943 1.62e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 42.99  E-value: 1.62e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1790 QQLDQLKGRIAELEMEKQKDRELSQALENEKNALLTQISAKDSELKLLEEEVTKRTTLNQQIQEELCRVTKLKE------ 1863
Cdd:COG1579     17 SELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVRNNKEyealqk 96

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1864 ---TAEEEKDDLEERLMNQLAELNGSIGNYYQDVTDAQIKNEQLESEMRNLQRCVSELEEEKQQLVKEKTKVESEIRKEY 1940
Cdd:COG1579     97 eieSLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAEREELAAKIPPEL 176


                   ...
gi 1039751022 1941 MEK 1943
Cdd:COG1579    177 LAL 179
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
800-1039 1.68e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 44.14  E-value: 1.68e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  800 QSQLEAKEREVREGTERLRDISQEMEGLSQALS--QKELEIAKMDQLLLEKQKDVETLQQTIQEKDQQVTELSFSMtekm 877
Cdd:COG4913    609 RAKLAALEAELAELEEELAEAEERLEALEAELDalQERREALQRLAEYSWDEIDVASAEREIAELEAELERLDASS---- 684

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  878 vqlneekfslgVEIKTLKEQLnllsrteeatkeqveesgagsslklghdesgqEGLQQELELLRKESEQRKRKLQAALIN 957
Cdd:COG4913    685 -----------DDLAALEEQL--------------------------------EELEAELEELEEELDELKGEIGRLEKE 721

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  958 RKELLQKVSQLEEELAKVREDSRKEIPFGENERRKLEEDRENRDDPEEWgtskWREVEASLKQTISEKEVELEGIRRDLK 1037
Cdd:COG4913    722 LEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGDAVERELREN----LEERIDALRARLNRAEEELERAMRAFN 797


                   ..
gi 1039751022 1038 EK 1039
Cdd:COG4913    798 RE 799
HMMR_N pfam15905
Hyaluronan mediated motility receptor N-terminal; HMMR_N is the N-terminal region of ...
 832-1081 1.84e-03

Hyaluronan mediated motility receptor N-terminal; HMMR_N is the N-terminal region of eukaryotic hyaluronan-mediated motility receptor proteins. The protein is functionally associated with BRCA1 and thus predicted to be a common, low-penetrance breast cancer candidate.


Pssm-ID: 464932 [Multi-domain]  Cd Length: 329  Bit Score: 43.26  E-value: 1.84e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  832 SQKELEIAKmDQLLLEKQKDVETLQQTIQEKDQQVTELSFSMTE-KMVQLNEEKFSLGVEIKTLKEQLNLLSRTEEATKE 910
Cdd:pfam15905   65 SQKNLKESK-DQKELEKEIRALVQERGEQDKRLQALEEELEKVEaKLNAAVREKTSLSASVASLEKQLLELTRVNELLKA 143

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  911 QVEESGAGSSLKLGHDESGQegLQQELELLRKE----SEQRKRKLQAALINRKELLQKVSQLEEELAKVREDSRKE---- 982
Cdd:pfam15905  144 KFSEDGTQKKMSSLSMELMK--LRNKLEAKMKEvmakQEGMEGKLQVTQKNLEHSKGKVAQLEEKLVSTEKEKIEEkset 221

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  983 ------IPFGENERRKLEEDRENRDDPEEWGTSKWREVEaSLKQTISEKEVELEGIRRDLKEKTA-AEEELQAVVQRMTR 1055
Cdd:pfam15905  222 eklleyITELSCVSEQVEKYKLDIAQLEELLKEKNDEIE-SLKQSLEEKEQELSKQIKDLNEKCKlLESEKEELLREYEE 300

                          250       260
                   ....*....|....*....|....*.
gi 1039751022 1056 DLQSKTKQIDLLQEEVTENQATIQKL 1081
Cdd:pfam15905  301 KEQTLNAELEELKEKLTLEEQEHQKL 326
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
2674-2845 1.86e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 44.14  E-value: 1.86e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2674 AQIQAFGRSMSSLQDSRDHATEELGDLKKKYDASLKELAQLKEWQDSSREGDVLSQAAFPLSTSENVLSRLEKLNQQLTS 2753
Cdd:COG4913    610 AKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEIDVASAEREIAELEAELERLDASSDDLAA 689

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2754 KDEQLLHLSSELESSHNQVQSISKAMTSLQNERDRLWSELEKFRKSEEGKQRAAAPSAASSPAEV-------QSLKKAMS 2826
Cdd:COG4913    690 LEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERfaaalgdAVERELRE 769

                          170
                   ....*....|....*....
gi 1039751022 2827 SLQNDRDRLLKELKNLQQQ 2845
Cdd:COG4913    770 NLEERIDALRARLNRAEEE 788
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 721-1342 1.88e-03

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 43.95  E-value: 1.88e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  721 VLAELRARVQELESSLAEAEKQ-RGLDYESQRAQHNLLteQIHSLSIEAKSKDVKIEalqreLDGVQLQFCEQGTQMKTL 799
Cdd:pfam15921  225 ILRELDTEISYLKGRIFPVEDQlEALKSESQNKIELLL--QQHQDRIEQLISEHEVE-----ITGLTEKASSARSQANSI 297

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  800 QSQLEAKEREVREGTerlrdiSQEMEGLSqalsqkELEiAKMDQLLLEKQKDVETLQQTIQEKDQQVTELSFSMTEKMV- 878
Cdd:pfam15921  298 QSQLEIIQEQARNQN------SMYMRQLS------DLE-STVSQLRSELREAKRMYEDKIEELEKQLVLANSELTEARTe 364

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  879 --QLNEEKFSLGVEIKTLKEQLNLLSRTEEATKEQ---VEESGAGSSLKLGH-----DESGQE--GLQQELELLRKESEQ 946
Cdd:pfam15921  365 rdQFSQESGNLDDQLQKLLADLHKREKELSLEKEQnkrLWDRDTGNSITIDHlrrelDDRNMEvqRLEALLKAMKSECQG 444

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  947 RKRKLQAALINRKELLQKVSQLEEELAKVREDSRKEIPFGENERRKLEEDRENRDDPEEWGTSKWREVEAS------LKQ 1020
Cdd:pfam15921  445 QMERQMAAIQGKNESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEATnaeitkLRS 524

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1021 TISEKEVELEGIRRDLKEKTAAEEELQAVVQRMTrdlqSKTKQIDLLQEEVtENQATIQKLVTGTMDAGNGGSAAPVKET 1100
Cdd:pfam15921  525 RVDLKLQELQHLKNEGDHLRNVQTECEALKLQMA----EKDKVIEILRQQI-ENMTQLVGQHGRTAGAMQVEKAQLEKEI 599

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1101 ------AASSPPGAGGEEHWKPELEGRILDLEKDKTQLQKKLQEALIARKAIlkkAQEKEKQLKE------ELREQKDAY 1168
Cdd:pfam15921  600 ndrrleLQEFKILKDKKDAKIRELEARVSDLELEKVKLVNAGSERLRAVKDI---KQERDQLLNEvktsrnELNSLSEDY 676

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1169 HHLQGQFHEQNKEKENIADQLRqLQCQARESIDRQLPGTGQQEPGPPAPSLE-GISLEDTEPASESDLHAAQpsppGETA 1247
Cdd:pfam15921  677 EVLKRNFRNKSEEMETTTNKLK-MQLKSAQSELEQTRNTLKSMEGSDGHAMKvAMGMQKQITAKRGQIDALQ----SKIQ 751

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1248 ALQATVSVAqiQAQLKEMEVEKEELELKVSSIASELAKKSEEVLLLQDQINEQGLEIQNL-----KAASVEAQAHTELLK 1322
Cdd:pfam15921  752 FLEEAMTNA--NKEKHFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANMevaldKASLQFAECQDIIQR 829

                          650       660
                   ....*....|....*....|
gi 1039751022 1323 QELESSQLKVAGLEHLKTLQ 1342
Cdd:pfam15921  830 QEQESVRLKLQHTLDVKELQ 849
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 652-1382 2.02e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 43.90  E-value: 2.02e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  652 LKTQVLELETSLHTAE-ETYKRNLSEKVKEISSLTQLSEEVKESAEEARSTLAAVTEERDQLLYQVKEL--DVLAELRAR 728
Cdd:TIGR02169  216 LLKEKREYEGYELLKEkEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLgeEEQLRVKEK 295

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  729 VQELESSLAEAE------KQRGLDYESQRAQhnlLTEQIHSLSIEAKSKDVKIEALQRELDGVQLQFCEQGTQMKTLQSQ 802
Cdd:TIGR02169  296 IGELEAEIASLErsiaekERELEDAEERLAK---LEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAE 372

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  803 LEAKEREVREGTERLRDISQEMEGLSQALSQKELEIAKMDQLLLEKQKDVETLQQTIQEKDQQVTELSFSMTEK------ 876
Cdd:TIGR02169  373 LEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKaleikk 452

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  877 -----------MVQLNEEKFSLGVEIKTLKEQLNLLSR---TEEATKEQVEESGAGSSLKLGHDESGQEGLQQELELLRK 942
Cdd:TIGR02169  453 qewkleqlaadLSKYEQELYDLKEEYDRVEKELSKLQRelaEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLGS 532

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  943 ESEQRKRKLQAALINRKELL----QKVSQLEEELAKVREDSRKE-IPFGENERRKLEEDRENRD------------DPEE 1005
Cdd:TIGR02169  533 VGERYATAIEVAAGNRLNNVvvedDAVAKEAIELLKRRKAGRATfLPLNKMRDERRDLSILSEDgvigfavdlvefDPKY 612

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1006 WGTSKW--------REVEASLKQTISEKEVELEGirrDLKEKTAA--------------EEELQAVVQRMTRDLQSKTKQ 1063
Cdd:TIGR02169  613 EPAFKYvfgdtlvvEDIEAARRLMGKYRMVTLEG---ELFEKSGAmtggsraprggilfSRSEPAELQRLRERLEGLKRE 689

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1064 IDLLQEEVTEnqatIQKLVTGTMDAGnggSAAPVKETAASSPPGAGGEEHWKpeLEGRILDLEKDKTQLQKKLQEALIAR 1143
Cdd:TIGR02169  690 LSSLQSELRR----IENRLDELSQEL---SDASRKIGEIEKEIEQLEQEEEK--LKERLEELEEDLSSLEQEIENVKSEL 760

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1144 KAILKKAQEKEKQLKEELREQKDAYHHLQGQFHEQ-NKEKENIADQLRQLQCQAREsIDRQLPgtgqqepgppAPSLEGI 1222
Cdd:TIGR02169  761 KELEARIEELEEDLHKLEEALNDLEARLSHSRIPEiQAELSKLEEEVSRIEARLRE-IEQKLN----------RLTLEKE 829

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1223 SLEDTEPASESDLHAAQPSPPGETAALQA-TVSVAQIQAQLKEMEVEKEELELKVSSIASELAKKSEEVLLLQDQINEQG 1301
Cdd:TIGR02169  830 YLEKEIQELQEQRIDLKEQIKSIEKEIENlNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELE 909

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1302 LEIQNLKAASVEAQAHTELLKQELESSQLKVAGLEHLKTLQPELDALHKHMGQKEEEVNYL-----------------YG 1364
Cdd:TIGR02169  910 AQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELSLEDVQAELQRVEEEIRALepvnmlaiqeyeevlkrLD 989

                          810
                   ....*....|....*...
gi 1039751022 1365 QLSEKEQTLTTVQTEMVE 1382
Cdd:TIGR02169  990 ELKEKRAKLEEERKAILE 1007
PLN03229 PLN03229
acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional
 646-999 2.18e-03

acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional


Pssm-ID: 178768 [Multi-domain]  Cd Length: 762  Bit Score: 43.69  E-value: 2.18e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  646 QGELERLKTQVLELETSLHTAEETYKRNLSEKVKEISSLtQLSEEVKESAEEARstLAAVTEE------RDQLLYQVkel 719
Cdd:PLN03229   435 EGEVEKLKEQILKAKESSSKPSELALNEMIEKLKKEIDL-EYTEAVIAMGLQER--LENLREEfskansQDQLMHPV--- 508

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  720 dvLAELRARV-QELESSLAEAEkqrglDYESQRAQHNLLTEqiHSLSIEAKSKDVKIEALQRELDgvqlQFCEQGTQMKT 798
Cdd:PLN03229   509 --LMEKIEKLkDEFNKRLSRAP-----NYLSLKYKLDMLNE--FSRAKALSEKKSKAEKLKAEIN----KKFKEVMDRPE 575

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  799 LQSQLEA-KEREVREGTERLRDISQEM-EGLSQALSQKELEIAK----MD-QLLLEKQKDVETLQQTIQEkdqqvtelsf 871
Cdd:PLN03229   576 IKEKMEAlKAEVASSGASSGDELDDDLkEKVEKMKKEIELELAGvlksMGlEVIGVTKKNKDTAEQTPPP---------- 645

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  872 SMTEKMVQLNEEkfsLGVEIKTLKEQLNLLSRTEEatkeqveesgagssLKLGHDESGQEGLQQELELLRKESEQRKRKL 951
Cdd:PLN03229   646 NLQEKIESLNEE---INKKIERVIRSSDLKSKIEL--------------LKLEVAKASKTPDVTEKEKIEALEQQIKQKI 708

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*...
gi 1039751022  952 QAALiNRKELLQKVSQLEEELAKVREDSRkeipfGENERRKLEEDREN 999
Cdd:PLN03229   709 AEAL-NSSELKEKFEELEAELAAARETAA-----ESNGSLKNDDDKEE 750
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1009-1261 2.21e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 43.28  E-value: 2.21e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1009 SKWREVEASLKQTISEKEVELEGIRRDLKEKTAAEEELQAVVQRMTRDLQSKTKQIDLLQEEVTENQATIQKLVTGTMDA 1088
Cdd:COG3883     19 QAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARALYRS 98

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1089 GNGGSAAPVKETAASSppgagGEEHWKPELEGRILDLEKDKTQLQKKLQEALIARKAILKKAQEKEKQLKEELREQKDAy 1168
Cdd:COG3883     99 GGSVSYLDVLLGSESF-----SDFLDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAE- 172

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1169 hhLQGQFHEQNKEKENIADQLRQLQcQARESIDRQLPGTGQQEPGPPAPSLEGISLEDTEPASESDLHAAQPSPPGETAA 1248
Cdd:COG3883    173 --LEAQQAEQEALLAQLSAEEAAAE-AQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAASAAGA 249

                          250
                   ....*....|...
gi 1039751022 1249 LQATVSVAQIQAQ 1261
Cdd:COG3883    250 GAAGAAGAAAGSA 262
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
2496-2934 2.24e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 43.60  E-value: 2.24e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2496 IKDSQQKQLLDAQLQQNKELRNECTKLEERLKGLEAEKQSLQMSSDALQKEKQGLSKEIKNLQTQLTALQEEGTLGVYHA 2575
Cdd:COG4717     67 ELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEALEAELAELPE 146

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2576 Q---LKAKEEELQRLNMALSSSQKRTADLEEELVCVQKEATRKVSEIEDQLKKELKHLHHDAGIMRNETETAEERVAELA 2652
Cdd:COG4717    147 RleeLEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELE 226

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2653 RDLVEMEQKLLTVTKENKDLMAQIQAFGRSMSSLQDSRDHATEELGDLKKKYDASLKELAQL-------KEWQDSSREGD 2725
Cdd:COG4717    227 EELEQLENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALlflllarEKASLGKEAEE 306

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2726 VLSQAAFPLSTSENVLSRLEKLNQQLTSKDEQLLHLSSELESSHNQVQSISKAMTSLQneRDRLWSELEKFRKSEEGKQR 2805
Cdd:COG4717    307 LQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQ--LEELEQEIAALLAEAGVEDE 384

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2806 AAAPSAASSPAEVQSLKKAMSSLQNDRDRLLKELKNLqqqylqmsQEMTELRPLKAQLQESQDQTKALQVMEEELRQENL 2885
Cdd:COG4717    385 EELRAALEQAEEYQELKEELEELEEQLEELLGELEEL--------LEALDEEELEEELEELEEELEELEEELEELREELA 456

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2886 SWQHELRQLRMEKNSWEL-HERRMKEQFLMAISDKDQQLGHLQSLLRELR 2934
Cdd:COG4717    457 ELEAELEQLEEDGELAELlQELEELKAELRELAEEWAALKLALELLEEAR 506
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1915-2298 2.28e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 43.60  E-value: 2.28e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1915 VSELEEEKQQLVKEKTKVESEIRKEYMEKIQGAQKGPANKSHAKELQELLREKQQEVKQLQKDCIRYLERISALEKTVKA 1994
Cdd:COG4717     48 LERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQL 127

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1995 LEfvhtesqkdldvtkgnlaqAVEHRKKAQAELSSFKILLDDTQSEAARVladnlklkKELQSNKESIKSQIKQKDEDLL 2074
Cdd:COG4717    128 LP-------------------LYQELEALEAELAELPERLEELEERLEEL--------RELEEELEELEAELAELQEELE 180

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2075 RRLEQAEEKHRKEKKNMQEKLDALHREKAHVEETLAEIQVSLTRKDQEMKELQGSLDS---------------------- 2132
Cdd:COG4717    181 ELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAaaleerlkearlllliaaalla 260

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2133 -------------------------TLAQLAAFTKSMSSLQDDRDRVIDEA----------KKWERRFGDAIQTKEEEVR 2177
Cdd:COG4717    261 llglggsllsliltiagvlflvlglLALLFLLLAREKASLGKEAEELQALPaleeleeeelEELLAALGLPPDLSPEELL 340

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2178 LKEENCIALKDQLRQMAIHMEELKITVSRLEHDKEIWESKAQTE-----LQHHQKAYDKLQEENKELTSQLEDARQLYHD 2252
Cdd:COG4717    341 ELLDRIEELQELLREAEELEEELQLEELEQEIAALLAEAGVEDEeelraALEQAEEYQELKEELEELEEQLEELLGELEE 420

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|....*...
gi 1039751022 2253 SKNELTK--LESELKSLKDQTTDLNNSLEKCKEHENNLEGIIKQQEAD 2298
Cdd:COG4717    421 LLEALDEeeLEEELEELEEELEELEEELEELREELAELEAELEQLEED 468
PTZ00121 PTZ00121
MAEBL; Provisional
 1280-1739 2.55e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 43.98  E-value: 2.55e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1280 ASELAKKSEEVLLLQDQINEQGLEIqnlKAASVEAQAHTELLKQELESSQLKVAGLEHLKTLQPELDALHKHMGQKEEEV 1359
Cdd:PTZ00121  1317 ADEAKKKAEEAKKKADAAKKKAEEA---KKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKA 1393

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1360 NYLYGQLSEKEQTLTTVQTEMVEQERLIKALHTQLEMQAKEHEERLKQAQVEICELKKKPTELEEETNAKQQLQRKLQAA 1439
Cdd:PTZ00121  1394 DEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKAD 1473

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1440 LISRK-EALKENKSLQEQLSSARDAVERLTKSLADVESQVSVQNQEKDAVLGKLTILQEERdkliaemdrfllenqslsg 1518
Cdd:PTZ00121  1474 EAKKKaEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAK------------------- 1534

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1519 SCESLKLALGGLTEDKEKLMEELESVRSSKMAEstewqEKHKELQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQELY 1598
Cdd:PTZ00121  1535 KADEAKKAEEKKKADELKKAEELKKAEEKKKAE-----EAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKA 1609

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1599 AKLRSTESDKREREKQLQDAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEAQPVGGTGESMEAllssNSSLKEEL 1678
Cdd:PTZ00121  1610 EEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKA----EEAKKAEE 1685

                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1039751022 1679 EKITLEHKTLSKEFEALMAE---KDALSEETRNLKLQVEAQVLKQASLEATEKSDEPKDVIEEV 1739
Cdd:PTZ00121  1686 DEKKAAEALKKEAEEAKKAEelkKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEA 1749
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2233-2455 2.65e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.21  E-value: 2.65e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2233 QEENKELTSQLEDARQLYHDSKNELTKLESELKSLKDQTTDLNNSLEKCKEHENNLEGIIKQQEADIQNCKFSCEQLETD 2312
Cdd:COG4942     19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE 98

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2313 LAASRELTSRLHDEI-NAKEQKIISLLSGKEEAIQLA-----VEELHQQHSKEIKELENLLSQEEEENVALEEENKRALE 2386
Cdd:COG4942     99 LEAQKEELAELLRALyRLGRQPPLALLLSPEDFLDAVrrlqyLKYLAPARREQAEELRADLAELAALRAELEAERAELEA 178

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1039751022 2387 KTNQLTEALEAIKKESFEQKAQLDSFVKSMSSLQDDRDRIVSDYRQLEERHLSAILEKDQLIQDAAAEN 2455
Cdd:COG4942    179 LLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAG 247
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 2157-2828 2.75e-03

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 43.67  E-value: 2.75e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2157 EAKKWERRFGdaiQTKEEEVRLKEENcIALKDQLRQMAIHMEELKITVSRLEH-----DKEIWESKAqtELQHHQKAYDK 2231
Cdd:pfam12128  242 EFTKLQQEFN---TLESAELRLSHLH-FGYKSDETLIASRQEERQETSAELNQllrtlDDQWKEKRD--ELNGELSAADA 315

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2232 LQEENKELTSQLEDARQLYHDSKNELTKLESE-LKSLKDQTTDLNNSLEKCKEHENNLEGIIKQQEADI-QNCKFSCEQL 2309
Cdd:pfam12128  316 AVAKDRSELEALEDQHGAFLDADIETAAADQEqLPSWQSELENLEERLKALTGKHQDVTAKYNRRRSKIkEQNNRDIAGI 395

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2310 ETDLAASRELTSRLHDEINAKEQKIISLLSGKEEAIQLAVEELHQQHSKEIKELENLLSQEEEENVAleeenkraLEKTN 2389
Cdd:pfam12128  396 KDKLAKIREARDRQLAVAEDDLQALESELREQLEAGKLEFNEEEYRLKSRLGELKLRLNQATATPEL--------LLQLE 467

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2390 QLTEALEAIKKESFEQKAQLDSFVKSMSSLQDDRDRIVSDYRQLEERHLSAILEKDQLIQDAAAENNKLKEEmrgLRSHM 2469
Cdd:pfam12128  468 NFDERIERAREEQEAANAEVERLQSELRQARKRRDQASEALRQASRRLEERQSALDELELQLFPQAGTLLHF---LRKEA 544

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2470 DDLNSENAKLDAELVQYRRDLN-EVIAIKDSQQKQL----LDAQLQQNKELRNECTKLEERLKGLEAEKQSLQMSSDALQ 2544
Cdd:pfam12128  545 PDWEQSIGKVISPELLHRTDLDpEVWDGSVGGELNLygvkLDLKRIDVPEWAASEEELRERLDKAEEALQSAREKQAAAE 624

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2545 KEKQGLSKEIKNLQTQLTALQeegtlgvyhAQLKAKEEELQRLNMALSSSQKRtadLEEELVCVQKEATRKVSEIEDQlK 2624
Cdd:pfam12128  625 EQLVQANGELEKASREETFAR---------TALKNARLDLRRLFDEKQSEKDK---KNKALAERKDSANERLNSLEAQ-L 691

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2625 KELKHLHHDAgimrnetetAEERVAELARDLVEMEQKLLTVTKENKDLMAQIQAfgrsmsSLQDSRDHATEELGDLKKKY 2704
Cdd:pfam12128  692 KQLDKKHQAW---------LEEQKEQKREARTEKQAYWQVVEGALDAQLALLKA------AIAARRSGAKAELKALETWY 756

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2705 DASLKELAQlkewqdssrEGDVLSQAAFPLSTSENVLSRLEKLNQQLTSKDEQLLH-LSSELESSHNQVQSISKAMTSLQ 2783
Cdd:pfam12128  757 KRDLASLGV---------DPDVIAKLKREIRTLERKIERIAVRRQEVLRYFDWYQEtWLQRRPRLATQLSNIERAISELQ 827

                          650       660       670       680
                   ....*....|....*....|....*....|....*....|....*
gi 1039751022 2784 NERDRLWSELEKFRKSEEGKQRAAAPSAASSPAEVQSLKKAMSSL 2828
Cdd:pfam12128  828 QQLARLIADTKLRRAKLEMERKASEKQQVRLSENLRGLRCEMSKL 872
ClpA COG0542
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ...
 2521-2620 2.89e-03

ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440308 [Multi-domain]  Cd Length: 836  Bit Score: 43.53  E-value: 2.89e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2521 KLEERLKGLEAEKQSLQMSSDALQKEK-QGLSKEIKNLQTQLTAL----QEEGTLgvyHAQLKAKEEELQRLNMALSSSQ 2595
Cdd:COG0542    415 ELERRLEQLEIEKEALKKEQDEASFERlAELRDELAELEEELEALkarwEAEKEL---IEEIQELKEELEQRYGKIPELE 491

                           90       100
                   ....*....|....*....|....*
gi 1039751022 2596 KRTADLEEELVCVQKEATRKVSEIE 2620
Cdd:COG0542    492 KELAELEEELAELAPLLREEVTEED 516
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
131-342 3.11e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 43.37  E-value: 3.11e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  131 LDQSEQASQLDKSSAEMEDFVLMKQQLQEKEELISTLQ--TQLSQTQAEQAAQLSSMQQVV--------REKDARFETQV 200
Cdd:COG4913    218 LEEPDTFEAADALVEHFDDLERAHEALEDAREQIELLEpiRELAERYAAARERLAELEYLRaalrlwfaQRRLELLEAEL 297

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  201 RLHEDELLQLVTQsdvETEMQQKLRVMQRKLEEHEEALLGR-AQVVDLLQKELTSAEQRNQVLSQQLQLLEAEHNTLKNT 279
Cdd:COG4913    298 EELRAELARLEAE---LERLEARLDALREELDELEAQIRGNgGDRLEQLEREIERLERELEERERRRARLEALLAALGLP 374

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1039751022  280 METERQESKTLMEKVELEVAERKLSFHNLQEEMHQLQGQLERAGQAQADLETQYSALQQRHKT 342
Cdd:COG4913    375 LPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSN 437
PTZ00121 PTZ00121
MAEBL; Provisional
 2035-2758 3.20e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 43.59  E-value: 3.20e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2035 DDTQSEAARVLADNLKLKKELQSNKESIKSQIKQKDEDLlRRLEQ---AEEKHRKEKKNMQEklDALHREKAHVEETLAE 2111
Cdd:PTZ00121  1089 ADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDA-RKAEEarkAEDARKAEEARKAE--DAKRVEIARKAEDARK 1165

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2112 IQVSltRKDQEMKELQGsldstlAQLAAFTKSMSSLQDDRD-RVIDEAKKWERrfgdaIQTKEEEVRLKEENCIALKDQL 2190
Cdd:PTZ00121  1166 AEEA--RKAEDAKKAEA------ARKAEEVRKAEELRKAEDaRKAEAARKAEE-----ERKAEEARKAEDAKKAEAVKKA 1232

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2191 RQMAIHMEELKITVSRLEHDKEIWESKAQTELQHHQKAYDKLQEENK-ELTSQLEDARQLYHDSKNELTKLESELKSLKD 2269
Cdd:PTZ00121  1233 EEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKaDELKKAEEKKKADEAKKAEEKKKADEAKKKAE 1312

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2270 QTTDLNNSLEKCKEHENNLEGIIKQQEadiqnckfscEQLETDLAASRELTSRlHDEINAKEQKIISLLSGKEEAIQLAv 2349
Cdd:PTZ00121  1313 EAKKADEAKKKAEEAKKKADAAKKKAE----------EAKKAAEAAKAEAEAA-ADEAEAAEEKAEAAEKKKEEAKKKA- 1380

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2350 eELHQQHSKEIKELENLLSQEEEENVALEEENKRALEKtnqltEALEAIKKESFEQKAQLDSFVKSMSSLQDDRDRivsd 2429
Cdd:PTZ00121  1381 -DAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAK-----KKADEAKKKAEEKKKADEAKKKAEEAKKADEAK---- 1450

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2430 yRQLEERHLSAILEKDQLIQDAAAENNKLKEEMRglrshmddlNSENAKLDAELVQYRRDlneVIAIKDSQQKQLLDAQL 2509
Cdd:PTZ00121  1451 -KKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAK---------KADEAKKKAEEAKKKAD---EAKKAAEAKKKADEAKK 1517

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2510 QQNKELRNECTKLEERLKGLEAEKQSLQMSSDALQKEKQGLSKEIKNLQTQLTALQEEGTLGVYHAQL-----KAKEEEL 2584
Cdd:PTZ00121  1518 AEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEakkaeEARIEEV 1597

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2585 QRLNMALSSSQKRTADLEEElVCVQKEATRKVSEIE---DQLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQK 2661
Cdd:PTZ00121  1598 MKLYEEEKKMKAEEAKKAEE-AKIKAEELKKAEEEKkkvEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKK 1676

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2662 LLTVTKENKDLMAQIQAFGRSMSSLQDSRDHATEELGDLKKKYDASLKELAQLKEWQDSSREGDVLSQAAFPLSTSENVL 2741
Cdd:PTZ00121  1677 AEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEK 1756

                          730
                   ....*....|....*..
gi 1039751022 2742 SRLEKLNQQLTSKDEQL 2758
Cdd:PTZ00121  1757 KKIAHLKKEEEKKAEEI 1773
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1961-2177 3.37e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.83  E-value: 3.37e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1961 QELLREKQQEVKQLQKdciryleRISALEKTVKALEFVHTESQKDLDVTKGNLAQAVEHRKKAQAELSSFKILLDDTQSE 2040
Cdd:COG4942     19 ADAAAEAEAELEQLQQ-------EIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKE 91

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2041 AARVLADNLKLKKELqsnKESIKSQIKQKDEDLLRRLEQAEEKHRKEKknMQEKLDALHREKAHVEETLAEIQVSLTRKD 2120
Cdd:COG4942     92 IAELRAELEAQKEEL---AELLRALYRLGRQPPLALLLSPEDFLDAVR--RLQYLKYLAPARREQAEELRADLAELAALR 166

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1039751022 2121 QEMKELQGSLDSTLAQLAAFTKSMSSLQDDRDRVIDEAKKWERRFGDAIQTKEEEVR 2177
Cdd:COG4942    167 AELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAE 223
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1279-2037 3.49e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 43.13  E-value: 3.49e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1279 IASELAKKSEEVLLLQDQINEQGLEI----QNLKAASVEAQAHTE----LLKQELESSQLKVAGLEH-LKTLQPELDALH 1349
Cdd:TIGR02169  242 IERQLASLEEELEKLTEEISELEKRLeeieQLLEELNKKIKDLGEeeqlRVKEKIGELEAEIASLERsIAEKERELEDAE 321

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1350 KHMGQKEEEVNYLYGQLSEKEQTLTTVQTEMVEQERLIKALHTQLEMQAKEHEERLKQAQVEICELKKKPTELEEETNAK 1429
Cdd:TIGR02169  322 ERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREI 401

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1430 QQLQRklqaalisrkealkENKSLQEQLSSARDAVERLTKSLADVEsqvsvqnqekdavlGKLTILQEERDKLIAEMDRF 1509
Cdd:TIGR02169  402 NELKR--------------ELDRLQEELQRLSEELADLNAAIAGIE--------------AKINELEEEKEDKALEIKKQ 453

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1510 LLENQSLSGSCESLKLALGGLTEDKEKLMEELESVRSskmaestEWQEKHKELQKEYEVLLQSYENVSNEAERIQHVVES 1589
Cdd:TIGR02169  454 EWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQR-------ELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGT 526

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1590 VRQ--EKQELYAKLRSTESDKRerekqLQDAEQEMEEMKEKMRKFAKSKQ---------QKILELEEENDRLR------- 1651
Cdd:TIGR02169  527 VAQlgSVGERYATAIEVAAGNR-----LNNVVVEDDAVAKEAIELLKRRKagratflplNKMRDERRDLSILSedgvigf 601

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1652 -------------AEAQPVGGTG--ESMEA---------LLSSNSSLKEELEKITLEHKTLSKEFEALMAEKDALSEETR 1707
Cdd:TIGR02169  602 avdlvefdpkyepAFKYVFGDTLvvEDIEAarrlmgkyrMVTLEGELFEKSGAMTGGSRAPRGGILFSRSEPAELQRLRE 681

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1708 NL-KLQVEAQVLKQASLEATEKSDEPKDVIEEVTQAVVGKSQERDALSD-----SAKLEDSEAILMgdgakpgvsetfSS 1781
Cdd:TIGR02169  682 RLeGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQeeeklKERLEELEEDLS------------SL 749

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1782 HDDIKNYLQQLDQLKGRIAELEMEKQKDRELSQALENEKNAllTQISAKDSELKLLEEEVTKRTTLNQQIQEELCRVTKL 1861
Cdd:TIGR02169  750 EQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSH--SRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLE 827

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1862 KETAEEEKDDLEErlmnQLAELNGSIGNYYQDVTDAQIKNEQLESEMRNLQRCVSELEEEKQQLVKEKTKVESEIRKEYM 1941
Cdd:TIGR02169  828 KEYLEKEIQELQE----QRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELER 903

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1942 EKIQGAQKGPANKSHAKELQELLREKQQEVKQLQKDCIRYLE-------------RISALEKTVKALEFVHTESQKDLDV 2008
Cdd:TIGR02169  904 KIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEipeeelsledvqaELQRVEEEIRALEPVNMLAIQEYEE 983

                          810       820
                   ....*....|....*....|....*....
gi 1039751022 2009 TKGNLAQAVEHRKKAQAELSSFKILLDDT 2037
Cdd:TIGR02169  984 VLKRLDELKEKRAKLEEERKAILERIEEY 1012
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 1798-2393 3.98e-03

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 42.79  E-value: 3.98e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1798 RIAELEMEKQKDRELSQALENEKNALLTQISakdsELKLLEEevTKRTTLNQQIQEELCRVTKLKETAEEEKDDLEER-- 1875
Cdd:pfam05483  170 KTKKYEYEREETRQVYMDLNNNIEKMILAFE----ELRVQAE--NARLEMHFKLKEDHEKIQHLEEEYKKEINDKEKQvs 243

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1876 -LMNQLAELNGSIGNYYQDVTDAQIKNEQLESEMRNLQRCVSELEEEKQQLVKEKTKVeseirKEYMEKIQGAQKGPAN- 1953
Cdd:pfam05483  244 lLLIQITEKENKMKDLTFLLEESRDKANQLEEKTKLQDENLKELIEKKDHLTKELEDI-----KMSLQRSMSTQKALEEd 318

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1954 -KSHAKELQELLREKQQEVKQLQKDCIRYLERISALEKTVKALEFVHTESQKDLDVTKGNLAQAVEHRKKAQAELSSFKI 2032
Cdd:pfam05483  319 lQIATKTICQLTEEKEAQMEELNKAKAAHSFVVTEFEATTCSLEELLRTEQQRLEKNEDQLKIITMELQKKSSELEEMTK 398

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2033 LLDDTQ---SEAARVLADNLKLKKElQSNKESIKSQIKQKDEDLLRRLEQAEekhrKEKKNMQEKLDALHREKAHVEETL 2109
Cdd:pfam05483  399 FKNNKEvelEELKKILAEDEKLLDE-KKQFEKIAEELKGKEQELIFLLQARE----KEIHDLEIQLTAIKTSEEHYLKEV 473

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2110 AEIQVSLTRKDQEMKELQGSLDSTLAQLAAFTKSMS----SLQDDRDRVIDEAKKWERRFGDAIQTKEEEVRLKEE---- 2181
Cdd:pfam05483  474 EDLKTELEKEKLKNIELTAHCDKLLLENKELTQEASdmtlELKKHQEDIINCKKQEERMLKQIENLEEKEMNLRDElesv 553

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2182 ------NCIALKDQLRQMAIHMEELKITVSRLEHDKEIWESKA---QTELQHHQKAYDKLQEENKELTSQLEDARQLYHD 2252
Cdd:pfam05483  554 reefiqKGDEVKCKLDKSEENARSIEYEVLKKEKQMKILENKCnnlKKQIENKNKNIEELHQENKALKKKGSAENKQLNA 633

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2253 SKNELTKLESELKSLKDQTTDLNNSLEKCKE----HENNLEGIIKQQEADI-------QNCKFSCEQLETDLAASRELTS 2321
Cdd:pfam05483  634 YEIKVNKLELELASAKQKFEEIIDNYQKEIEdkkiSEEKLLEEVEKAKAIAdeavklqKEIDKRCQHKIAEMVALMEKHK 713

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1039751022 2322 RLHDEINAKEQKIISLLSGKEEAIQLAVEELHQQHSKEIKELENLLSQEEEENVALEEENKRALEKTNQLTE 2393
Cdd:pfam05483  714 HQYDKIIEERDSELGLYKNKEQEQSSAKAALEIELSNIKAELLSLKKQLEIEKEEKEKLKMEAKENTAILKD 785
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 847-1098 4.26e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.44  E-value: 4.26e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  847 EKQKDVETLQQTIQEKDQQVTelsfsmtekmvQLNEEKFSLGVEIKTLKEQLNLLSRTEEATKEQVEESGAgsslKLGHD 926
Cdd:COG4942     24 EAEAELEQLQQEIAELEKELA-----------ALKKEEKALLKQLAALERRIAALARRIRALEQELAALEA----ELAEL 88

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  927 ESGQEGLQQELELLRKESEQRKRKLQAALINRKELLQKVSQLEEELAKVREDSRKEIPFGENERRKLEEDREnrddpeew 1006
Cdd:COG4942     89 EKEIAELRAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLA-------- 160

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1007 gtsKWREVEASLKQTISEKEVELEGIRRDLKEKTAAEEELQAVVQRMTRDLQSKTKQIDLLQEEVTENQATIQKLVTGTM 1086
Cdd:COG4942    161 ---ELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAA 237

                          250
                   ....*....|..
gi 1039751022 1087 DAGNGGSAAPVK 1098
Cdd:COG4942    238 AAAERTPAAGFA 249
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
2513-2998 4.49e-03

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 42.74  E-value: 4.49e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2513 KELRNECTKLEERLKGLEAEKQSLQMSSDALQKEKQGLSKEIKNLQTQLTALQEE-GTLGVYHAQLKAKEEELQRLNMAL 2591
Cdd:PRK03918   168 GEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREElEKLEKEVKELEELKEEIEELEKEL 247

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2592 SSSQKRTADLEEELVCVQKEATRKVSEIEDqLKKELKHLhhdagimrNETETAEERVAELARDLVEMEQKLLTVTKENKD 2671
Cdd:PRK03918   248 ESLEGSKRKLEEKIRELEERIEELKKEIEE-LEEKVKEL--------KELKEKAEEYIKLSEFYEEYLDELREIEKRLSR 318

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2672 LMAQIQAFGRSMSSLQDSRdhatEELGDLKKKYDASLKELAQLKEWQDSSREGDVLSQAAFPLSTSENVLSrLEKLNQQL 2751
Cdd:PRK03918   319 LEEEINGIEERIKELEEKE----ERLEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLT-PEKLEKEL 393

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2752 TSKDEQLLHLSSELESshnqvqsISKAMTSLQNERDRLWSELEKFRKSE--------EGKQRAAAPSAASSPAEVQSLKK 2823
Cdd:PRK03918   394 EELEKAKEEIEEEISK-------ITARIGELKKEIKELKKAIEELKKAKgkcpvcgrELTEEHRKELLEEYTAELKRIEK 466

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2824 AMSSLQNDRDRLLKELKNLQQQyLQMSQEMTELRPLKAQLQESQDQTKALQVME--------EELRQENLSWQHELRQLR 2895
Cdd:PRK03918   467 ELKEIEEKERKLRKELRELEKV-LKKESELIKLKELAEQLKELEEKLKKYNLEElekkaeeyEKLKEKLIKLKGEIKSLK 545

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2896 MEKNSWELHERRmKEQFLMAISDKDQQLGHLQSLLRELRSSSQAQI------LSTQYQR-----QASPETSASLDGSQKL 2964
Cdd:PRK03918   546 KELEKLEELKKK-LAELEKKLDELEEELAELLKELEELGFESVEELeerlkeLEPFYNEylelkDAEKELEREEKELKKL 624

                          490       500       510
                   ....*....|....*....|....*....|....
gi 1039751022 2965 VYETELLRTQLNDSLKEIHQKELRIQQLNSKFSQ 2998
Cdd:PRK03918   625 EEELDKAFEELAETEKRLEELRKELEELEKKYSE 658
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
45-487 4.50e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 42.83  E-value: 4.50e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022   45 EALQEEKKAAENKIKKIKLHAKAKIMSLNKHMEEIKTQGGAAlppEAQAEELSKHNKSSTEEEMEIEKIKHELQEKEKLI 124
Cdd:COG4717     49 ERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEY---AELQEELEELEEELEELEAELEELREELEKLEKLL 125

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  125 SSLQAQLDQSEQASQLDKSSAEMEDFVLMKQQLQEKEELISTLQTQLSQTQAEQAAQLSSMQQVVREKDARFETQVRLHE 204
Cdd:COG4717    126 QLLPLYQELEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQ 205

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  205 DELLQLVTQSDV-------------ETEMQQKLRVMQRKLEEHEEALLGRAQVVDLLQKELTSAEQRNQVLSQQLQLLEA 271
Cdd:COG4717    206 QRLAELEEELEEaqeeleeleeeleQLENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGL 285

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  272 EHnTLKNTMETERQESKTLMEKVELEVAERKLSFHNLQEEMHQLQGQLERAGQAQADLETQYSALQQRH-KTEMEEKTAC 350
Cdd:COG4717    286 LA-LLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLrEAEELEEELQ 364

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  351 ILSLQKNEQELQSACAALKEENSKLLQEKHDQAAESAQAMRQLEDQLQQKSKEISQFVNKPNLQKNETASQtslpdvNNE 430
Cdd:COG4717    365 LEELEQEIAALLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEELEEELE------ELE 438

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1039751022  431 GDQAVMEETVASLQKRVVELENEKGALLlSSGELEELKAENEKLSSRITLLEAQNRA 487
Cdd:COG4717    439 EELEELEEELEELREELAELEAELEQLE-EDGELAELLQELEELKAELRELAEEWAA 494
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
2013-2651 4.70e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 42.98  E-value: 4.70e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2013 LAQAVEH---RKKAQAELSSFKILLDDTQSEAARVLADNLK-----LKKELQSNKESIkSQIKQKDEDLLRRLEQAEEKH 2084
Cdd:COG4913    254 LEPIRELaerYAAARERLAELEYLRAALRLWFAQRRLELLEaeleeLRAELARLEAEL-ERLEARLDALREELDELEAQI 332

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2085 R----KEKKNMQEKLDALHREKAHVEETLAEIQVSLTRKDQEMKELQGSLDSTLAQLAAFTKSMSSLQDDRDRVIDEAKK 2160
Cdd:COG4913    333 RgnggDRLEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEA 412

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2161 WERRFGDAIQTKEEEVR-LKE------ENCIALKDQLRqmaihmEELKITVSRL---------EHDKEIWESKAQTELqh 2224
Cdd:COG4913    413 ALRDLRRELRELEAEIAsLERrksnipARLLALRDALA------EALGLDEAELpfvgelievRPEEERWRGAIERVL-- 484

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2225 HQKAYDKLQEENkeltsQLEDARQLYHDSKNELT----KLESELKSLKDQTTDLNNSLEKCKEHENNLEGIIKQQEADIQ 2300
Cdd:COG4913    485 GGFALTLLVPPE-----HYAAALRWVNRLHLRGRlvyeRVRTGLPDPERPRLDPDSLAGKLDFKPHPFRAWLEAELGRRF 559

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2301 N--CKFSCEQLE-TDLAASRE-LTSRLHD--EINAKEQKIISLLSGKEEAIQLAVEElhqqhsKEIKELEnllsqeeeen 2374
Cdd:COG4913    560 DyvCVDSPEELRrHPRAITRAgQVKGNGTrhEKDDRRRIRSRYVLGFDNRAKLAALE------AELAELE---------- 623

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2375 valeeenkRALEKTNQLTEALEAIKKESFEQKAQLdSFVKSMSSLQDDRDRIVSDYRQLEERhLSAILEKDQLIQDAAAE 2454
Cdd:COG4913    624 --------EELAEAEERLEALEAELDALQERREAL-QRLAEYSWDEIDVASAEREIAELEAE-LERLDASSDDLAALEEQ 693

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2455 NNKLKEEMRGLRSHMDDLNSENAKLDAELVQYRRDLNEViaikdsqQKQLLDAQLQQNKELRnecTKLEERLKGLEAEKQ 2534
Cdd:COG4913    694 LEELEAELEELEEELDELKGEIGRLEKELEQAEEELDEL-------QDRLEAAEDLARLELR---ALLEERFAAALGDAV 763

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2535 SLQMsSDALQKEKQGLSKEIKNLQTQLTALQEEgtlgvYHAQLKAKEEELQRLNMALSSSQKRTADLEEElvcvqkEATR 2614
Cdd:COG4913    764 EREL-RENLEERIDALRARLNRAEEELERAMRA-----FNREWPAETADLDADLESLPEYLALLDRLEED------GLPE 831

                          650       660       670       680
                   ....*....|....*....|....*....|....*....|.
gi 1039751022 2615 KVSEIEDQLKK----ELKHLHHDagiMRNETETAEERVAEL 2651
Cdd:COG4913    832 YEERFKELLNEnsieFVADLLSK---LRRAIREIKERIDPL 869
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1964-2177 5.03e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 42.12  E-value: 5.03e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1964 LREKQQEVKQLQKDCIRYLERISALEKTVKALEFVHTESQKDLDVTKGNLAQAVEHRKKAQAELSSFKILLDDTQSEAAR 2043
Cdd:COG3883     18 IQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARALYR 97

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2044 VLADNLKLKKELQS-------NKESIKSQIKQKDEDLLRRLEQAEEKHRKEKKNMQEKLDALHREKAHVEETLAEIQVSL 2116
Cdd:COG3883     98 SGGSVSYLDVLLGSesfsdflDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAELEAQQ 177

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1039751022 2117 TRKDQEMKELQGSLDSTLAQLAAFTKSMSSLQDDRDRVIDEAKKWERRFGDAIQTKEEEVR 2177
Cdd:COG3883    178 AEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAAAA 238
46 PHA02562
endonuclease subunit; Provisional
 2406-2631 5.09e-03

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 42.31  E-value: 5.09e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2406 KAQLDSFVKSMSSLQDDRDRIVSDYRQLEERHLSAILEKDQLIQDAAAENNKLKEEMRGLRSHMDDLNSENAKLDAELVQ 2485
Cdd:PHA02562   194 QQQIKTYNKNIEEQRKKNGENIARKQNKYDELVEEAKTIKAEIEELTDELLNLVMDIEDPSAALNKLNTAAAKIKSKIEQ 273

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2486 YRRDlneviaIKDSQQKQLLDAQLQQNKELRNECTKLEERLKGLEaekQSLQMSSDALQKEKQ------GLSKEIKNLQT 2559
Cdd:PHA02562   274 FQKV------IKMYEKGGVCPTCTQQISEGPDRITKIKDKLKELQ---HSLEKLDTAIDELEEimdefnEQSKKLLELKN 344

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1039751022 2560 QLTalQEEGTLGVYHAQLKAKEEELQRLnmalsssQKRTADLEEELVCVQKEATRKVSEIEDqLKKELKHLH 2631
Cdd:PHA02562   345 KIS--TNKQSLITLVDKAKKVKAAIEEL-------QAEFVDNAEELAKLQDELDKIVKTKSE-LVKEKYHRG 406
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 2172-2716 5.13e-03

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 42.85  E-value: 5.13e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2172 KEEEVRLKEENCIALKDQLRQMAIHMEELKITVSRLEHDKEIWESKAQTELQhhqkaydkLQEENKELTSQLEDARQLYH 2251
Cdd:pfam01576    3 QEEEMQAKEEELQKVKERQQKAESELKELEKKHQQLCEEKNALQEQLQAETE--------LCAEAEEMRARLAARKQELE 74

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2252 DSkneLTKLESELKSLKDQTTDLNNSLEKCKEHENNLEGIIKQQEADIQ-------NCKFSCEQLETDLAASRELTSRLH 2324
Cdd:pfam01576   75 EI---LHELESRLEEEEERSQQLQNEKKKMQQHIQDLEEQLDEEEAARQklqlekvTTEAKIKKLEEDILLLEDQNSKLS 151

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2325 DEINAKEQKIISLLS--GKEEAIQLAVEELHQQHSKEIKELENLLSQEEEENVALEEENKRALEKTNQLTEALEAIKKES 2402
Cdd:pfam01576  152 KERKLLEERISEFTSnlAEEEEKAKSLSKLKNKHEAMISDLEERLKKEEKGRQELEKAKRKLEGESTDLQEQIAELQAQI 231

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2403 FEQKAQLDSFVKSMSSLQDDRDRIVSDYRQLEERHLSAILEKDQLIQDAAAE----------NNKLKEEMRGLRSHMDD- 2471
Cdd:pfam01576  232 AELRAQLAKKEEELQAALARLEEETAQKNNALKKIRELEAQISELQEDLESEraarnkaekqRRDLGEELEALKTELEDt 311

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2472 LNSENA------KLDAELVQYRRDLNEVIAIKDSQQKQLLDAQLQQNKElrnectkLEERLKGLEAEKQSLQMSSDALQK 2545
Cdd:pfam01576  312 LDTTAAqqelrsKREQEVTELKKALEEETRSHEAQLQEMRQKHTQALEE-------LTEQLEQAKRNKANLEKAKQALES 384

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2546 EKQGLSKEIKNLQTqltalqeeGTLGVYHAQLKAkEEELQRLNMALSSSQKRTADLEEELVCVQKEaTRKVSEIEDQLKK 2625
Cdd:pfam01576  385 ENAELQAELRTLQQ--------AKQDSEHKRKKL-EGQLQELQARLSESERQRAELAEKLSKLQSE-LESVSSLLNEAEG 454

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2626 ELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLTVTKENKDLMAQIQAFGRSMSSLQDSRDHATEELGDLKKKYD 2705
Cdd:pfam01576  455 KNIKLSKDVSSLESQLQDTQELLQEETRQKLNLSTRLRQLEDERNSLQEQLEEEEEAKRNVERQLSTLQAQLSDMKKKLE 534

                          570
                   ....*....|.
gi 1039751022 2706 ASLKELAQLKE 2716
Cdd:pfam01576  535 EDAGTLEALEE 545
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 2153-2884 5.33e-03

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 42.73  E-value: 5.33e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2153 RVIDEAKKWERRFGDAIQTKEEEVRLKE---ENCIALKDQLRQMAIHMEELKITVSRLEHD--------KEIWESKAQT- 2220
Cdd:TIGR00606  186 KALETLRQVRQTQGQKVQEHQMELKYLKqykEKACEIRDQITSKEAQLESSREIVKSYENEldplknrlKEIEHNLSKIm 265

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2221 ELQHHQKAYDKLQEENKELTSQLEDAR-QLYHDSKNELTKLE----SELKSLKDQTTDLNNSLEKckeheNNLEGIIKQQ 2295
Cdd:TIGR00606  266 KLDNEIKALKSRKKQMEKDNSELELKMeKVFQGTDEQLNDLYhnhqRTVREKERELVDCQRELEK-----LNKERRLLNQ 340

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2296 EADIQNCKFSCEQLETDLAASRELTSRLHDEINAKEQKIISLLSGKEEAIQL--AVEELHQQHSKEIKELENLLSQEEEE 2373
Cdd:TIGR00606  341 EKTELLVEQGRLQLQADRHQEHIRARDSLIQSLATRLELDGFERGPFSERQIknFHTLVIERQEDEAKTAAQLCADLQSK 420

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2374 NVALEEENKRALEKTNQLTEALEAIKKESFEQKAQLDSFVKSMSSLQDDRDRIVSDYRQL--EERHLSaILEKDQLIQDA 2451
Cdd:TIGR00606  421 ERLKQEQADEIRDEKKGLGRTIELKKEILEKKQEELKFVIKELQQLEGSSDRILELDQELrkAERELS-KAEKNSLTETL 499

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2452 AAENNKLKEEMRGLRSHMDDLNSENAKLDAE---------LVQYRRDLNEVIAIKDSQQKQLLDAQL---QQNKELRNEC 2519
Cdd:TIGR00606  500 KKEVKSLQNEKADLDRKLRKLDQEMEQLNHHtttrtqmemLTKDKMDKDEQIRKIKSRHSDELTSLLgyfPNKKQLEDWL 579

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2520 TKLEERLKGLEAEKQSLQMSSDALQKEKQGLSKEIKNLQTQLTALqEEGTLGVYHAQlkAKEEELQRLNMALSSSQKRTA 2599
Cdd:TIGR00606  580 HSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSY-EDKLFDVCGSQ--DEESDLERLKEEIEKSSKQRA 656

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2600 DLEEElvcvqkeatrkvSEIEDQLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLTVTKENKDLMAQIQAF 2679
Cdd:TIGR00606  657 MLAGA------------TAVYSQFITQLTDENQSCCPVCQRVFQTEAELQEFISDLQSKLRLAPDKLKSTESELKKKEKR 724

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2680 GRSMSSLQDSR----DHATEELGDLKKKYDASLKELAQLKewQDSSREGDVLSQAAFPLSTSENVLSR---LEKLNQQLT 2752
Cdd:TIGR00606  725 RDEMLGLAPGRqsiiDLKEKEIPELRNKLQKVNRDIQRLK--NDIEEQETLLGTIMPEEESAKVCLTDvtiMERFQMELK 802

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2753 SKDEQLLHLSSELESS--HNQVQSISKAMTSLQNERDRLWSELEKFRKSEEGKQRaaapsaasspaEVQSLKKAMSSLQN 2830
Cdd:TIGR00606  803 DVERKIAQQAAKLQGSdlDRTVQQVNQEKQEKQHELDTVVSKIELNRKLIQDQQE-----------QIQHLKSKTNELKS 871

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1039751022 2831 DRDRLLKELKNLQQQYLQMSQEMTELRPLKAQLQESQDQTKALQVMEEELRQEN 2884
Cdd:TIGR00606  872 EKLQIGTNLQRRQQFEEQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEK 925
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 1383-1971 5.40e-03

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 42.40  E-value: 5.40e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1383 QERLIKALHTQLEMQAKEHEERLKQAQVEicelkkkpTELEEETNAKQqlqRKLQAALISRKEALKENKSLQEQLSSARD 1462
Cdd:pfam05483  200 EELRVQAENARLEMHFKLKEDHEKIQHLE--------EEYKKEINDKE---KQVSLLLIQITEKENKMKDLTFLLEESRD 268

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1463 AVERLtksladvESQVSVQNQEKDAVLGKLTILQEERDKLIAEMDRFLLENQSLSGSCESLKLALGGLTEDKEKLMEELE 1542
Cdd:pfam05483  269 KANQL-------EEKTKLQDENLKELIEKKDHLTKELEDIKMSLQRSMSTQKALEEDLQIATKTICQLTEEKEAQMEELN 341

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1543 SVRSSKMAESTEWQEKHKELQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQELYAKLRSTESDKREREKQL---QDAE 1619
Cdd:pfam05483  342 KAKAAHSFVVTEFEATTCSLEELLRTEQQRLEKNEDQLKIITMELQKKSSELEEMTKFKNNKEVELEELKKILaedEKLL 421

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1620 QEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEAQPVGGTGESMEALLSSNSSLKEELEKITLEHKTLSKEFEALMAEK 1699
Cdd:pfam05483  422 DEKKQFEKIAEELKGKEQELIFLLQAREKEIHDLEIQLTAIKTSEEHYLKEVEDLKTELEKEKLKNIELTAHCDKLLLEN 501

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1700 DALSEETRNLKLQVEAQvlkqasleateksdePKDVIEevtqavvGKSQERDALSDSAKLEDSEAILMgDGAKPGVSETF 1779
Cdd:pfam05483  502 KELTQEASDMTLELKKH---------------QEDIIN-------CKKQEERMLKQIENLEEKEMNLR-DELESVREEFI 558

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1780 SSHDDIKNylqQLDQLKGRIAELEMEKQKDRELSQALENEKNALLTQISAKDSELKLLEEE----VTKRTTLNQQIQEEL 1855
Cdd:pfam05483  559 QKGDEVKC---KLDKSEENARSIEYEVLKKEKQMKILENKCNNLKKQIENKNKNIEELHQEnkalKKKGSAENKQLNAYE 635

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1856 CRVTKLKETAEEEKDDLEErlmnqlaelngSIGNYYQDVTDAQIKNEQLESEMrnlqrcvseleEEKQQLVKEKTKVESE 1935
Cdd:pfam05483  636 IKVNKLELELASAKQKFEE-----------IIDNYQKEIEDKKISEEKLLEEV-----------EKAKAIADEAVKLQKE 693

                          570       580       590
                   ....*....|....*....|....*....|....*.
gi 1039751022 1936 IRKEYMEKIqgAQKGPANKSHAKELQELLREKQQEV 1971
Cdd:pfam05483  694 IDKRCQHKI--AEMVALMEKHKHQYDKIIEERDSEL 727
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2491-2723 5.61e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.06  E-value: 5.61e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2491 NEVIAIKDSQQKQLLDAQLQQNKELRnectKLEERLKGLEAEKQSLQMSSDALQKEKQGLSKEIKNLQTQLTALQEEgtL 2570
Cdd:COG4942     19 ADAAAEAEAELEQLQQEIAELEKELA----ALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKE--I 92

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2571 GVYHAQLKAKEEELQRLnmaLSSSQKRTADLEEELVCVQKEATRKVSEIEDqLKKELKHLHHDAGIMRNETETAEERVAE 2650
Cdd:COG4942     93 AELRAELEAQKEELAEL---LRALYRLGRQPPLALLLSPEDFLDAVRRLQY-LKYLAPARREQAEELRADLAELAALRAE 168

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1039751022 2651 LARDLVEMEQKLLTVTKENKDLMAQIQAFGRSMSSLQDSRDHATEELGDLKKKYDASLKELAQLKEWQDSSRE 2723
Cdd:COG4942    169 LEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAE 241
PRK12704 PRK12704
phosphodiesterase; Provisional
 2019-2181 5.65e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 42.07  E-value: 5.65e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2019 HRKKAQAELSSFKILLDDTQsEAARVLADNLKLKKELQSNKESIKSQIKQKDEDLLRR--LEQAEEKHRKEKKNMQEKLD 2096
Cdd:PRK12704    25 RKKIAEAKIKEAEEEAKRIL-EEAKKEAEAIKKEALLEAKEEIHKLRNEFEKELRERRneLQKLEKRLLQKEENLDRKLE 103

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2097 ALHREKAHVEETLAEI---QVSLTRKDQEMKELQGSLDSTLAQLAAFTKsmsslQDDRDRVIDEAKKwERRFGDAIQTKE 2173
Cdd:PRK12704   104 LLEKREEELEKKEKELeqkQQELEKKEEELEELIEEQLQELERISGLTA-----EEAKEILLEKVEE-EARHEAAVLIKE 177


                   ....*...
gi 1039751022 2174 EEVRLKEE 2181
Cdd:PRK12704   178 IEEEAKEE 185
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1394-1584 6.83e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 42.31  E-value: 6.83e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1394 LEMQAKEHEERLKQAQVEICELKKK------PTELEEETNAKQQLQRKLQAALISRKEALKENKSLQEQLSSARDAVERL 1467
Cdd:COG3206    180 LEEQLPELRKELEEAEAALEEFRQKnglvdlSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLGSGPDALPEL 259

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1468 TKS--LADVESQVSVQNQEKDAVLGKLT-------ILQEERDKLIAEMdrflleNQSLSGSCESLKLALGGLTEDKEKLM 1538
Cdd:COG3206    260 LQSpvIQQLRAQLAELEAELAELSARYTpnhpdviALRAQIAALRAQL------QQEAQRILASLEAELEALQAREASLQ 333

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*.
gi 1039751022 1539 EELESVRSsKMAESTEWQEKHKELQKEYEVLLQSYENVSNEAERIQ 1584
Cdd:COG3206    334 AQLAQLEA-RLAELPELEAELRRLEREVEVARELYESLLQRLEEAR 378
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 722-954 7.09e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 41.67  E-value: 7.09e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  722 LAELRARVQELESSLAEAEKQRgldyESQRAQHNLLTEQIHSLSIEAKSKDVKIEALQRELDGVQlqfceqgTQMKTLQS 801
Cdd:COG4942     29 LEQLQQEIAELEKELAALKKEE----KALLKQLAALERRIAALARRIRALEQELAALEAELAELE-------KEIAELRA 97

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  802 QLEAKEREVRE---GTERLRDISQEMEGLSQA-LSQKELEIAKMDQLLLEKQKDVETLQQTIQEKDQQVTELSFSMTEKM 877
Cdd:COG4942     98 ELEAQKEELAEllrALYRLGRQPPLALLLSPEdFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELE 177

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  878 VQLNE---EKFSLGVEIKTLKEQLNLLSRTEEATKEQVEESgagsslklghdESGQEGLQQELELLRKESEQRKRKLQAA 954
Cdd:COG4942    178 ALLAEleeERAALEALKAERQKLLARLEKELAELAAELAEL-----------QQEAEELEALIARLEAEAAAAAERTPAA 246
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 822-1045 7.25e-03

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 42.03  E-value: 7.25e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  822 QEMEGLSQALSQKELEIAKMDQLLLE--KQKDVETLQQTIQEKDQQVTElSFSMTEKMVQLNEEKFSLGVEIKTLKEQLN 899
Cdd:pfam17380  348 RELERIRQEERKRELERIRQEEIAMEisRMRELERLQMERQQKNERVRQ-ELEAARKVKILEEERQRKIQQQKVEMEQIR 426

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  900 llSRTEEATKEQVEESGAGSSLKLGHDESGQEGLQQELELLRKESEQRKRKLQAALINRKELLQKVSQLEEELAKVREDS 979
Cdd:pfam17380  427 --AEQEEARQREVRRLEEERAREMERVRLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRRKILEKELEER 504

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1039751022  980 RKEIPFGENERRKLEEDRENRDdpeewgTSKWREVEASLKQTISEKEVELEGIRRDLKEKTAAEEE 1045
Cdd:pfam17380  505 KQAMIEEERKRKLLEKEMEERQ------KAIYEEERRREAEEERRKQQEMEERRRIQEQMRKATEE 564
46 PHA02562
endonuclease subunit; Provisional
 1786-1976 7.59e-03

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 41.92  E-value: 7.59e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1786 KNYLQQLDQLKG-RIAELEMEKQKDRELSQALENEKNALLTQISAKDSELKLLEEEVTKRTTLNQQIQEELCRVTKLKET 1864
Cdd:PHA02562   201 NKNIEEQRKKNGeNIARKQNKYDELVEEAKTIKAEIEELTDELLNLVMDIEDPSAALNKLNTAAAKIKSKIEQFQKVIKM 280

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1865 AEE------------EKDDLEERLMNQLAELNGSignyYQDVTDAQIKNEQLESEMRNLQRCVSEL----EEEKQQL--- 1925
Cdd:PHA02562   281 YEKggvcptctqqisEGPDRITKIKDKLKELQHS----LEKLDTAIDELEEIMDEFNEQSKKLLELknkiSTNKQSLitl 356

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1039751022 1926 VKEKTKVESEIRKeymekiqgAQKGPANksHAKELQELLREKQQEVKQLQK 1976
Cdd:PHA02562   357 VDKAKKVKAAIEE--------LQAEFVD--NAEELAKLQDELDKIVKTKSE 397
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
2505-2936 7.72e-03

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 41.97  E-value: 7.72e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2505 LDAQLQQNKELRNECTKLEERLKGLEAEKQSLQMSSDALQKEKQGLSKEIKNLQTQLTALQE-----------EGTLGVY 2573
Cdd:PRK03918   226 LEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKElkekaeeyiklSEFYEEY 305

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2574 HAQLKAKEEELQRLNMALSSSQKRTADLE------EELVCVQKEATRKVSEIEDQLKKELKHLHHDAGIMRNETETAEER 2647
Cdd:PRK03918   306 LDELREIEKRLSRLEEEINGIEERIKELEekeerlEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLT 385

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2648 VAELARDLVEMEQKLLTVTKENKDLMAQIQAFGRSMSSLQDS---------------RDHATEELGDLKKKYDASLKELA 2712
Cdd:PRK03918   386 PEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAieelkkakgkcpvcgRELTEEHRKELLEEYTAELKRIE 465

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2713 -QLKEWQDSSREGDVLSQAAFPLSTSENVLSRLEKLNQQLTSKDEQLLHLSSE-LESSHNQVQSISKAMTSLQNERDRLW 2790
Cdd:PRK03918   466 kELKEIEEKERKLRKELRELEKVLKKESELIKLKELAEQLKELEEKLKKYNLEeLEKKAEEYEKLKEKLIKLKGEIKSLK 545

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2791 SELEKFrKSEEGKQRAAAPSAASSPAEVQSLKKAMSSL----QNDRDRLLKELKNLQQQYLQMSQEMTELRPLKAQLQES 2866
Cdd:PRK03918   546 KELEKL-EELKKKLAELEKKLDELEEELAELLKELEELgfesVEELEERLKELEPFYNEYLELKDAEKELEREEKELKKL 624

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1039751022 2867 QDQTKALQVMEEELRQENLSWQHELRQLRMEKNSWELHE-RRMKEQFLMAISDKDQQLGHLQSLLRELRSS 2936
Cdd:PRK03918   625 EEELDKAFEELAETEKRLEELRKELEELEKKYSEEEYEElREEYLELSRELAGLRAELEELEKRREEIKKT 695
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1305-1487 8.24e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 41.93  E-value: 8.24e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1305 QNLKAASVEAQAHTELLKQELESSQLKVAGLEH-LKTLQPELDALhkhmgQKEEEVNYLYGQLSEKEQTLTTVQTEMVEQ 1383
Cdd:COG3206    164 QNLELRREEARKALEFLEEQLPELRKELEEAEAaLEEFRQKNGLV-----DLSEEAKLLLQQLSELESQLAEARAELAEA 238

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1384 ERLIKALHTQLEMQA------------KEHEERLKQAQVEICELKKKPTE--------LEEETNAKQQLQRKLQAALISR 1443
Cdd:COG3206    239 EARLAALRAQLGSGPdalpellqspviQQLRAQLAELEAELAELSARYTPnhpdvialRAQIAALRAQLQQEAQRILASL 318

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....
gi 1039751022 1444 KEALKENKSLQEQLSSARDAVERLTKSLADVESQVSVQNQEKDA 1487
Cdd:COG3206    319 EAELEALQAREASLQAQLAQLEARLAELPELEAELRRLEREVEV 362
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 8-364 8.32e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 41.98  E-value: 8.32e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022    8 MESTQEDALHRLAEAEKLVVELKDIIS---QKDVQLQQKDEALQEEKKAAENKIKKIKlhakAKIMSLNKHMEEIKTQGg 84
Cdd:TIGR02169  686 LKRELSSLQSELRRIENRLDELSQELSdasRKIGEIEKEIEQLEQEEEKLKERLEELE----EDLSSLEQEIENVKSEL- 760

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022   85 AALPPEAQAEELSKHNKSSTEEEMEIEKIKHELQEKEKLISSLQAQLdqSEQASQLDKSSAEMEDFVLMKQQLQEKEELI 164
Cdd:TIGR02169  761 KELEARIEELEEDLHKLEEALNDLEARLSHSRIPEIQAELSKLEEEV--SRIEARLREIEQKLNRLTLEKEYLEKEIQEL 838

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  165 STLQTQLSQTQAEQAAQLSSMQQVVREKDARFE---TQVRLHEDELLQLVTQSDvetEMQQKLRVMQRKLEEHEEALLGR 241
Cdd:TIGR02169  839 QEQRIDLKEQIKSIEKEIENLNGKKEELEEELEeleAALRDLESRLGDLKKERD---ELEAQLRELERKIEELEAQIEKK 915

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  242 AQVVDLLQKELTSAEQRNqvlsqqlqlleAEHNTLKNTMETERQESKTLmEKVELEVAErklsfhnLQEEMHQLQGQLER 321
Cdd:TIGR02169  916 RKRLSELKAKLEALEEEL-----------SEIEDPKGEDEEIPEEELSL-EDVQAELQR-------VEEEIRALEPVNML 976

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|...
gi 1039751022  322 AGQAQADLETQYSALQQRHKTEMEEKTACILSLQKNEQELQSA 364
Cdd:TIGR02169  977 AIQEYEEVLKRLDELKEKRAKLEEERKAILERIEEYEKKKREV 1019
Crescentin pfam19220
Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament ...
 648-841 8.75e-03

Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament proteins, named crescentin, whose cytoskeletal function is required for the vibrioid and helical shapes of Caulobacter crescentus. Without crescentin, the cells adopt a straight-rod morphology. Crescentin has characteriztic features of IF proteins including the ability to assemble into filaments in vitro without energy or cofactor requirements. In vivo, crescentin forms a helical structure that colocalizes with the inner cell curvatures beneath the cytoplasmic membrane.


Pssm-ID: 437057 [Multi-domain]  Cd Length: 401  Bit Score: 41.59  E-value: 8.75e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  648 ELERLKTQVLELETSLHTAEETYkRNLSEKVKEISS-LTQLSEEVKESAEEARSTLAAVTEERdqllyqvkelDVLAELR 726
Cdd:pfam19220   42 ELPQAKSRLLELEALLAQERAAY-GKLRRELAGLTRrLSAAEGELEELVARLAKLEAALREAE----------AAKEELR 110

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022  727 ARVQELESSLAEAEKQrgLDYESQRAQHnlLTEQIHSLSIEAKSKDVKIEALQRELDGVQLQFCEQGTQMKTLQSQLEAK 806
Cdd:pfam19220  111 IELRDKTAQAEALERQ--LAAETEQNRA--LEEENKALREEAQAAEKALQRAEGELATARERLALLEQENRRLQALSEEQ 186

                          170       180       190
                   ....*....|....*....|....*....|....*
gi 1039751022  807 EREVREGTERLRDISQEMEGLSQALSQKELEIAKM 841
Cdd:pfam19220  187 AAELAELTRRLAELETQLDATRARLRALEGQLAAE 221
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1775-2260 9.70e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 41.82  E-value: 9.70e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1775 VSETFSSHDDIKNYLQQLDQLKGRI----AELEMEKQKDRElsQALENEKNALLTQISAKDSELKLLEEEVTK-RTTLNQ 1849
Cdd:COG4913    257 IRELAERYAAARERLAELEYLRAALrlwfAQRRLELLEAEL--EELRAELARLEAELERLEARLDALREELDElEAQIRG 334

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1850 QIQEELCRVTKLKETAEEEKDDLEERLmNQLAELNGSIGnyYQDVTDAqiknEQLESEMRNLQRCVSELEEEKQQLVKEK 1929
Cdd:COG4913    335 NGGDRLEQLEREIERLERELEERERRR-ARLEALLAALG--LPLPASA----EEFAALRAEAAALLEALEEELEALEEAL 407

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1930 TKVESEIRkeymekiqgaqkgpankshakELQELLREKQQEVKQLQ--KDCI-RYLERI-----SALEKTVKALEF---- 1997
Cdd:COG4913    408 AEAEAALR---------------------DLRRELRELEAEIASLErrKSNIpARLLALrdalaEALGLDEAELPFvgel 466

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 1998 --VHTESQK--------------DLDVTKGNLAQAVEH--RKKAQAELSSFKILLDDTQSEAARVLADNLKLKKELQSNK 2059
Cdd:COG4913    467 ieVRPEEERwrgaiervlggfalTLLVPPEHYAAALRWvnRLHLRGRLVYERVRTGLPDPERPRLDPDSLAGKLDFKPHP 546

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2060 --ESIKSQIKQK-------DEDLLRRLEQA--------EEKHRKEKK-------------NMQEKLDALHREKAHVEETL 2109
Cdd:COG4913    547 frAWLEAELGRRfdyvcvdSPEELRRHPRAitragqvkGNGTRHEKDdrrrirsryvlgfDNRAKLAALEAELAELEEEL 626

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2110 AEIQVSLTRKDQEMKELQGSLDsTLAQLAAFT----------KSMSSLQDDRDRV------IDEAKKWERRFGDAIQTKE 2173
Cdd:COG4913    627 AEAEERLEALEAELDALQERRE-ALQRLAEYSwdeidvasaeREIAELEAELERLdassddLAALEEQLEELEAELEELE 705

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2174 EEVRLKEENCIALKDQLRQMAIHMEELKITVSRLEHDKEIWESKAQTELQHHQKAYDKLQEENKELTSQLEDARQLYHDS 2253
Cdd:COG4913    706 EELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGDAVERELRENLEERIDALRARLNRA 785


                   ....*..
gi 1039751022 2254 KNELTKL 2260
Cdd:COG4913    786 EEELERA 792
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2541-2798 9.84e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 41.29  E-value: 9.84e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2541 DALQKEKQGLSKEIKNLQTQLTALQeegtlgvyhAQLKAKEEELQRLNMALSSSQKRTADLEEELvcvqKEATRKVSEIE 2620
Cdd:COG4942     23 AEAEAELEQLQQEIAELEKELAALK---------KEEKALLKQLAALERRIAALARRIRALEQEL----AALEAELAELE 89

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2621 DQLKKelkhlhhdagiMRNETETAEERVAELARDLVEMEQKLLTVTKENKDLMAQIQAFGRSMSSLQDSRDHATEELGDL 2700
Cdd:COG4942     90 KEIAE-----------LRAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRAD 158

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751022 2701 KKKYDASLKELAQLKEWQDSSREgdvlsqaafplstseNVLSRLEKLNQQLTSKDEQLLHLSSELESSHNQVQSISKAMT 2780
Cdd:COG4942    159 LAELAALRAELEAERAELEALLA---------------ELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAE 223

                          250
                   ....*....|....*...
gi 1039751022 2781 SLQNERDRLWSELEKFRK 2798
Cdd:COG4942    224 ELEALIARLEAEAAAAAE 241
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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