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Conserved domains on  [gi|1039751285|ref|XP_017172520|]
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transport and Golgi organization 2 homolog isoform X1 [Mus musculus]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
TANGO2 pfam05742
Transport and Golgi organization 2; In eukaryotes this family is predicted to play a role in ...
1-259 6.87e-120

Transport and Golgi organization 2; In eukaryotes this family is predicted to play a role in protein secretion and Golgi organization. In plants this family includes Swiss:A9X6Y0, which is involved in water permeability in the cuticles of fruit. Swiss:P54797 has been found to be expressed during early embryogenesis in mice. This protein contains a conserved NRDE motif. This gene has been characterized in Drosophila melanogaster and named as transport and Golgi organization 2, hence the name Tango2.


:

Pssm-ID: 461729  Cd Length: 255  Bit Score: 343.09  E-value: 6.87e-120
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751285   1 MCIIFFKFDPRPvsknAYRLILAANRDEFYNRPSKLADFWGNNSEILSGLDMEeGKAGGTWLGISTRGKLGALTNYLQPR 80
Cdd:pfam05742   1 MCILFFAWNAHP----KYPLILAANRDEFLNRPTAPAHWWEENPNILGGRDLE-GREGGTWLGITKQGRIAALTNYREPS 75
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751285  81 QEP----DARGRGELVSHFLTSDMDSLSYLKKVSTEGHLYNGFNIIAADLSTSKGdvVCYYGNRGEPEPIVLTPGTYGLS 156
Cdd:pfam05742  76 SGPpdavGARSRGLLVNDFLTSNPDPEEYLEELAKEADKYNGFNLLVGDLNGSKS--LAYISNRGNPTPDQLSPGIHGLS 153
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751285 157 NALLETPWKKLCFGKQLFMEAVEQSEALPKDVLVTQLLDVLNNEEaQLPDPAIEDQGQEYVQPilnkYAAVCVRC----A 232
Cdd:pfam05742 154 NSLLDSPWPKVERGKRLFEELVEESVEDSEDQLIEELFDLLSDDT-LPRDPELPDTGPEWERL----LSSIFIPPippgG 228
                         250       260
                  ....*....|....*....|....*..
gi 1039751285 233 TYGTRTNTIILVDANGHVTFTERSMLD 259
Cdd:pfam05742 229 RYGTRSQTVILVDKDGKVTFIERTLYD 255
 
Name Accession Description Interval E-value
TANGO2 pfam05742
Transport and Golgi organization 2; In eukaryotes this family is predicted to play a role in ...
1-259 6.87e-120

Transport and Golgi organization 2; In eukaryotes this family is predicted to play a role in protein secretion and Golgi organization. In plants this family includes Swiss:A9X6Y0, which is involved in water permeability in the cuticles of fruit. Swiss:P54797 has been found to be expressed during early embryogenesis in mice. This protein contains a conserved NRDE motif. This gene has been characterized in Drosophila melanogaster and named as transport and Golgi organization 2, hence the name Tango2.


Pssm-ID: 461729  Cd Length: 255  Bit Score: 343.09  E-value: 6.87e-120
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751285   1 MCIIFFKFDPRPvsknAYRLILAANRDEFYNRPSKLADFWGNNSEILSGLDMEeGKAGGTWLGISTRGKLGALTNYLQPR 80
Cdd:pfam05742   1 MCILFFAWNAHP----KYPLILAANRDEFLNRPTAPAHWWEENPNILGGRDLE-GREGGTWLGITKQGRIAALTNYREPS 75
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751285  81 QEP----DARGRGELVSHFLTSDMDSLSYLKKVSTEGHLYNGFNIIAADLSTSKGdvVCYYGNRGEPEPIVLTPGTYGLS 156
Cdd:pfam05742  76 SGPpdavGARSRGLLVNDFLTSNPDPEEYLEELAKEADKYNGFNLLVGDLNGSKS--LAYISNRGNPTPDQLSPGIHGLS 153
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751285 157 NALLETPWKKLCFGKQLFMEAVEQSEALPKDVLVTQLLDVLNNEEaQLPDPAIEDQGQEYVQPilnkYAAVCVRC----A 232
Cdd:pfam05742 154 NSLLDSPWPKVERGKRLFEELVEESVEDSEDQLIEELFDLLSDDT-LPRDPELPDTGPEWERL----LSSIFIPPippgG 228
                         250       260
                  ....*....|....*....|....*..
gi 1039751285 233 TYGTRTNTIILVDANGHVTFTERSMLD 259
Cdd:pfam05742 229 RYGTRSQTVILVDKDGKVTFIERTLYD 255
Tango2 COG3332
Uncharacterized stress-responsive protein, TANGO2 (Transport and Golgi organisation 2) family, ...
1-276 1.22e-83

Uncharacterized stress-responsive protein, TANGO2 (Transport and Golgi organisation 2) family, contains NRDE motif [General function prediction only];


Pssm-ID: 442561  Cd Length: 257  Bit Score: 251.33  E-value: 1.22e-83
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751285   1 MCIIFFKFDPRPvsknAYRLILAANRDEFYNRPSKLADFWGNNSEILSGLDMEegkAGGTWLGISTRGKLGALTNYLQP- 79
Cdd:COG3332     1 MCLIAFAWQPHP----DYPLVLAANRDEFYARPTAPPARWPDAPGVLAGRDLE---AGGTWLGVNRHGRFAALTNRRDPs 73
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751285  80 RQEPDARGRGELVSHFLTSDMDSLSYLKKVSTEGHLYNGFNIIAADlstskGDVVCYYGNRGEPEPIVLTPGTYGLSNAL 159
Cdd:COG3332    74 GPPAGARSRGELVLDFLAGESAPAAYLALLALDAAAYNGFNLLVGD-----ADRLFYLSNRGDALVRRLAPGVHGLSNAL 148
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751285 160 LETPWKKLCFGKQLFMEAVEQSEALPkdvlvTQLLDVLNNEE----AQLPDPAIedqGQEYVQpilnKYAAVCVRCATYG 235
Cdd:COG3332   149 LDTPWPKVARLKAALAAALAPDDPDP-----DALFALLADRTpapdAELPDTGV---GLEWER----LLSSIFIHGPGYG 216
                         250       260       270       280
                  ....*....|....*....|....*....|....*....|.
gi 1039751285 236 TRTNTIILVDANGHVTFTERSmLDKDTSRWETNTYEFTLQS 276
Cdd:COG3332   217 TRSSTLLALDADGRVEFAERR-FDADGPPCGTRRFRFTLLS 256
 
Name Accession Description Interval E-value
TANGO2 pfam05742
Transport and Golgi organization 2; In eukaryotes this family is predicted to play a role in ...
1-259 6.87e-120

Transport and Golgi organization 2; In eukaryotes this family is predicted to play a role in protein secretion and Golgi organization. In plants this family includes Swiss:A9X6Y0, which is involved in water permeability in the cuticles of fruit. Swiss:P54797 has been found to be expressed during early embryogenesis in mice. This protein contains a conserved NRDE motif. This gene has been characterized in Drosophila melanogaster and named as transport and Golgi organization 2, hence the name Tango2.


Pssm-ID: 461729  Cd Length: 255  Bit Score: 343.09  E-value: 6.87e-120
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751285   1 MCIIFFKFDPRPvsknAYRLILAANRDEFYNRPSKLADFWGNNSEILSGLDMEeGKAGGTWLGISTRGKLGALTNYLQPR 80
Cdd:pfam05742   1 MCILFFAWNAHP----KYPLILAANRDEFLNRPTAPAHWWEENPNILGGRDLE-GREGGTWLGITKQGRIAALTNYREPS 75
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751285  81 QEP----DARGRGELVSHFLTSDMDSLSYLKKVSTEGHLYNGFNIIAADLSTSKGdvVCYYGNRGEPEPIVLTPGTYGLS 156
Cdd:pfam05742  76 SGPpdavGARSRGLLVNDFLTSNPDPEEYLEELAKEADKYNGFNLLVGDLNGSKS--LAYISNRGNPTPDQLSPGIHGLS 153
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751285 157 NALLETPWKKLCFGKQLFMEAVEQSEALPKDVLVTQLLDVLNNEEaQLPDPAIEDQGQEYVQPilnkYAAVCVRC----A 232
Cdd:pfam05742 154 NSLLDSPWPKVERGKRLFEELVEESVEDSEDQLIEELFDLLSDDT-LPRDPELPDTGPEWERL----LSSIFIPPippgG 228
                         250       260
                  ....*....|....*....|....*..
gi 1039751285 233 TYGTRTNTIILVDANGHVTFTERSMLD 259
Cdd:pfam05742 229 RYGTRSQTVILVDKDGKVTFIERTLYD 255
Tango2 COG3332
Uncharacterized stress-responsive protein, TANGO2 (Transport and Golgi organisation 2) family, ...
1-276 1.22e-83

Uncharacterized stress-responsive protein, TANGO2 (Transport and Golgi organisation 2) family, contains NRDE motif [General function prediction only];


Pssm-ID: 442561  Cd Length: 257  Bit Score: 251.33  E-value: 1.22e-83
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751285   1 MCIIFFKFDPRPvsknAYRLILAANRDEFYNRPSKLADFWGNNSEILSGLDMEegkAGGTWLGISTRGKLGALTNYLQP- 79
Cdd:COG3332     1 MCLIAFAWQPHP----DYPLVLAANRDEFYARPTAPPARWPDAPGVLAGRDLE---AGGTWLGVNRHGRFAALTNRRDPs 73
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751285  80 RQEPDARGRGELVSHFLTSDMDSLSYLKKVSTEGHLYNGFNIIAADlstskGDVVCYYGNRGEPEPIVLTPGTYGLSNAL 159
Cdd:COG3332    74 GPPAGARSRGELVLDFLAGESAPAAYLALLALDAAAYNGFNLLVGD-----ADRLFYLSNRGDALVRRLAPGVHGLSNAL 148
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039751285 160 LETPWKKLCFGKQLFMEAVEQSEALPkdvlvTQLLDVLNNEE----AQLPDPAIedqGQEYVQpilnKYAAVCVRCATYG 235
Cdd:COG3332   149 LDTPWPKVARLKAALAAALAPDDPDP-----DALFALLADRTpapdAELPDTGV---GLEWER----LLSSIFIHGPGYG 216
                         250       260       270       280
                  ....*....|....*....|....*....|....*....|.
gi 1039751285 236 TRTNTIILVDANGHVTFTERSmLDKDTSRWETNTYEFTLQS 276
Cdd:COG3332   217 TRSSTLLALDADGRVEFAERR-FDADGPPCGTRRFRFTLLS 256
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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