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Conserved domains on  [gi|1039768907|ref|XP_017175916|]
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cylicin-2 isoform X1 [Mus musculus]

Protein Classification

Cylicin_N domain-containing protein( domain architecture ID 10633634)

Cylicin_N domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Cylicin_N pfam15241
Cylicin N-terminus; This is the N-terminus of cylicin proteins, which may play a role in ...
 8-113 2.99e-49

Cylicin N-terminus; This is the N-terminus of cylicin proteins, which may play a role in spermatid differentiation.


:

Pssm-ID: 464581  Cd Length: 107  Bit Score: 167.22  E-value: 2.99e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039768907   8 KVTYGAYDNYIPVSELSKKSWNQQYFSLAFPKPPRPGKKRRSLPSQLQNNTaPVIDEEKL-GVHRPPL-WMHRSLMRISE 85
Cdd:pfam15241   1 KVNIGTYDNYIPVSESSKKSWNQQHFSLTFPKPPRPGKKRRSRPSELQETV-PRHDERKLkEDQKPAHiWMHRSLMKISE 79

                          90       100
                  ....*....|....*....|....*...
gi 1039768907  86 RPSVYLAARKGLIPKPLHFGKGESKSVG 113
Cdd:pfam15241  80 RPSIYLAARRQPPFRHPYTPKTHSKKAE 107
PTZ00121 super family cl31754
MAEBL; Provisional
 200-490 2.61e-11

MAEBL; Provisional


The actual alignment was detected with superfamily member PTZ00121:

Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 67.47  E-value: 2.61e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039768907  200 EGEKAGSKKEAKVTKKGSTGKDSTSESGGEKAgsKKEAKVTKKGSTGKDSASESGGEKAGSKKEAKVTKKGSTGKDSASE 279
Cdd:PTZ00121  1276 EARKADELKKAEEKKKADEAKKAEEKKKADEA--KKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAE 1353

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039768907  280 SGGEKA-GSKKEAKVTKKGSTGKDSASESGGEKAGSKKEAKVTKKGSKSKDSASESGGEKAGSKKEAKVTKKGSTGKDSA 358
Cdd:PTZ00121  1354 AAADEAeAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKA 1433

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039768907  359 SESGgEKAGSKKEAKATKKGSKSKDSAsESGGEKAGSKKEAKATKKGSKSKDSASESGGEKAGSKKEAKATKKGSKDKTS 438
Cdd:PTZ00121  1434 DEAK-KKAEEAKKADEAKKKAEEAKKA-EEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKK 1511

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1039768907  439 ISESgsEKAGSKKEAKTTKKgSKDKVSATESggEKAGSKKEAKATKKGSKDK 490
Cdd:PTZ00121  1512 ADEA--KKAEEAKKADEAKK-AEEAKKADEA--KKAEEKKKADELKKAEELK 1558
 
Name Accession Description Interval E-value
Cylicin_N pfam15241
Cylicin N-terminus; This is the N-terminus of cylicin proteins, which may play a role in ...
 8-113 2.99e-49

Cylicin N-terminus; This is the N-terminus of cylicin proteins, which may play a role in spermatid differentiation.


Pssm-ID: 464581  Cd Length: 107  Bit Score: 167.22  E-value: 2.99e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039768907   8 KVTYGAYDNYIPVSELSKKSWNQQYFSLAFPKPPRPGKKRRSLPSQLQNNTaPVIDEEKL-GVHRPPL-WMHRSLMRISE 85
Cdd:pfam15241   1 KVNIGTYDNYIPVSESSKKSWNQQHFSLTFPKPPRPGKKRRSRPSELQETV-PRHDERKLkEDQKPAHiWMHRSLMKISE 79

                          90       100
                  ....*....|....*....|....*...
gi 1039768907  86 RPSVYLAARKGLIPKPLHFGKGESKSVG 113
Cdd:pfam15241  80 RPSIYLAARRQPPFRHPYTPKTHSKKAE 107
PTZ00121 PTZ00121
MAEBL; Provisional
 200-490 2.61e-11

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 67.47  E-value: 2.61e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039768907  200 EGEKAGSKKEAKVTKKGSTGKDSTSESGGEKAgsKKEAKVTKKGSTGKDSASESGGEKAGSKKEAKVTKKGSTGKDSASE 279
Cdd:PTZ00121  1276 EARKADELKKAEEKKKADEAKKAEEKKKADEA--KKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAE 1353

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039768907  280 SGGEKA-GSKKEAKVTKKGSTGKDSASESGGEKAGSKKEAKVTKKGSKSKDSASESGGEKAGSKKEAKVTKKGSTGKDSA 358
Cdd:PTZ00121  1354 AAADEAeAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKA 1433

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039768907  359 SESGgEKAGSKKEAKATKKGSKSKDSAsESGGEKAGSKKEAKATKKGSKSKDSASESGGEKAGSKKEAKATKKGSKDKTS 438
Cdd:PTZ00121  1434 DEAK-KKAEEAKKADEAKKKAEEAKKA-EEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKK 1511

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1039768907  439 ISESgsEKAGSKKEAKTTKKgSKDKVSATESggEKAGSKKEAKATKKGSKDK 490
Cdd:PTZ00121  1512 ADEA--KKAEEAKKADEAKK-AEEAKKADEA--KKAEEKKKADELKKAEELK 1558
2A1904 TIGR00927
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ...
 191-452 1.60e-06

K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273344 [Multi-domain]  Cd Length: 1096  Bit Score: 51.53  E-value: 1.60e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039768907  191 KGKDSASESEGEKAGSKKEAKVTKKGSTGKdstsESGGEKAGSKKEAKVTKKGSTGkDSASESGGEKA--GSKKEAKVTK 268
Cdd:TIGR00927  632 KGDVAEAEHTGERTGEEGERPTEAEGENGE----ESGGEAEQEGETETKGENESEG-EIPAERKGEQEgeGEIEAKEADH 706

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039768907  269 KGSTGKDSASESGGEKAGSKKEAKVTKKGSTGKDSASESGGEKAGSKKEAKVTKKGSKSKDSASESGGEKAGSKKEAKVT 348
Cdd:TIGR00927  707 KGETEAEEVEHEGETEAEGTEDEGEIETGEEGEEVEDEGEGEAEGKHEVETEGDRKETEHEGETEAEGKEDEDEGEIQAG 786

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039768907  349 KKGSTGKDSASESGGEKAGSKKEAKATKKGSKSKDSASESGGEKAGSKKEAKATKKG-SKSKDSASESGGEKAGSKKEAK 427
Cdd:TIGR00927  787 EDGEMKGDEGAEGKVEHEGETEAGEKDEHEGQSETQADDTEVKDETGEQELNAENQGeAKQDEKGVDGGGGSDGGDSEEE 866

                          250       260
                   ....*....|....*....|....*
gi 1039768907  428 ATKKGSKDKTSISESGSEKAGSKKE 452
Cdd:TIGR00927  867 EEEEEEEEEEEEEEEEEEEEEEENE 891
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 145-503 2.27e-04

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 44.51  E-value: 2.27e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039768907 145 DKEGSPKPAKKNIPRDSQKDKGRVSSDSE-GEKAGVKKGSKKVKNTPKGKDSASESE-GEKAGSKKEAKVTKKGSTGKDS 222
Cdd:NF033609  549 DEPGEIEPIPEDSDSDPGSDSGSDSSNSDsGSDSGSDSTSDSGSDSASDSDSASDSDsASDSDSASDSDSASDSDSASDS 628

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039768907 223 TSESGGEKAGSKKEAKVTKKGSTGKDSASESGGEKAGSKKEAKVTKKGSTGKDSASESGGEKAGSKKEAKVTKKGSTGKD 302
Cdd:NF033609  629 DSASDSDSASDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 708

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039768907 303 SASESGGEKAGSKKEAKVTKKGSKSKDSASESGGEKAGSKKEAKVTKKGSTGKDSASESGGEKAGSKKEAKATKKGSKSK 382
Cdd:NF033609  709 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 788

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039768907 383 DSASESGGEKAGSKKEAKATKKGSKSKDSASESGGEKAGSKKEAKATKKGSKDKTSISESGSEKAGSKKEAKTTKKGSKD 462
Cdd:NF033609  789 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSESDSNSDSESGS 868

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|.
gi 1039768907 463 KVSATESGGEKAGSKKEAKATKKGSKDKVSGTESGGEKAGS 503
Cdd:NF033609  869 NNNVVPPNSPKNGTNASNKNEAKDSKEPLPDTGSEDEANTS 909
 
Name Accession Description Interval E-value
Cylicin_N pfam15241
Cylicin N-terminus; This is the N-terminus of cylicin proteins, which may play a role in ...
 8-113 2.99e-49

Cylicin N-terminus; This is the N-terminus of cylicin proteins, which may play a role in spermatid differentiation.


Pssm-ID: 464581  Cd Length: 107  Bit Score: 167.22  E-value: 2.99e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039768907   8 KVTYGAYDNYIPVSELSKKSWNQQYFSLAFPKPPRPGKKRRSLPSQLQNNTaPVIDEEKL-GVHRPPL-WMHRSLMRISE 85
Cdd:pfam15241   1 KVNIGTYDNYIPVSESSKKSWNQQHFSLTFPKPPRPGKKRRSRPSELQETV-PRHDERKLkEDQKPAHiWMHRSLMKISE 79

                          90       100
                  ....*....|....*....|....*...
gi 1039768907  86 RPSVYLAARKGLIPKPLHFGKGESKSVG 113
Cdd:pfam15241  80 RPSIYLAARRQPPFRHPYTPKTHSKKAE 107
PTZ00121 PTZ00121
MAEBL; Provisional
 200-490 2.61e-11

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 67.47  E-value: 2.61e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039768907  200 EGEKAGSKKEAKVTKKGSTGKDSTSESGGEKAgsKKEAKVTKKGSTGKDSASESGGEKAGSKKEAKVTKKGSTGKDSASE 279
Cdd:PTZ00121  1276 EARKADELKKAEEKKKADEAKKAEEKKKADEA--KKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAE 1353

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039768907  280 SGGEKA-GSKKEAKVTKKGSTGKDSASESGGEKAGSKKEAKVTKKGSKSKDSASESGGEKAGSKKEAKVTKKGSTGKDSA 358
Cdd:PTZ00121  1354 AAADEAeAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKA 1433

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039768907  359 SESGgEKAGSKKEAKATKKGSKSKDSAsESGGEKAGSKKEAKATKKGSKSKDSASESGGEKAGSKKEAKATKKGSKDKTS 438
Cdd:PTZ00121  1434 DEAK-KKAEEAKKADEAKKKAEEAKKA-EEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKK 1511

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1039768907  439 ISESgsEKAGSKKEAKTTKKgSKDKVSATESggEKAGSKKEAKATKKGSKDK 490
Cdd:PTZ00121  1512 ADEA--KKAEEAKKADEAKK-AEEAKKADEA--KKAEEKKKADELKKAEELK 1558
PTZ00121 PTZ00121
MAEBL; Provisional
 137-490 4.95e-11

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 66.32  E-value: 4.95e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039768907  137 KEKTALKTDKEGSPKPAKKNIPRDSQKDKGRVSSDSEGEKAGVKKGSKKVKNTPKGKDSASESEGEKAGSKKEAKVTKKG 216
Cdd:PTZ00121  1238 DAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKA 1317

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039768907  217 STGKDSTSESGGEKAGSKKEAKVTKKGSTGKDSASESGGEKA-GSKKEAKVTKKGSTGKDSASESGGEKAGSKKEAKVTK 295
Cdd:PTZ00121  1318 DEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAeAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAK 1397

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039768907  296 KGSTGKDSASESGGEKAGSKKEAKVTKKGSKSKDSASESgGEKAGSKKEAKVTKKGSTGKDSAsESGGEKAGSKKEAKAT 375
Cdd:PTZ00121  1398 KKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEA-KKKAEEAKKADEAKKKAEEAKKA-EEAKKKAEEAKKADEA 1475

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039768907  376 KKGSKSKDSASESGGEKAGSKKEAKATKKGSKSKDSASESggEKAGSKKEAKATKKGSKDKTSiseSGSEKAGSKKEAKT 455
Cdd:PTZ00121  1476 KKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEA--KKAEEAKKADEAKKAEEAKKA---DEAKKAEEKKKADE 1550

                          330       340       350
                   ....*....|....*....|....*....|....*
gi 1039768907  456 TKKGSKDKvsatesggeKAGSKKEAKATKKGSKDK 490
Cdd:PTZ00121  1551 LKKAEELK---------KAEEKKKAEEAKKAEEDK 1576
PTZ00121 PTZ00121
MAEBL; Provisional
 163-522 1.40e-09

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 61.70  E-value: 1.40e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039768907  163 KDKGRVSSDSEGEKAGVKKGSKKVKNTPKGKDSASESEGEKAGSKKEAKVTKKGSTGKDSTSESGGEKAGSKKEAK---- 238
Cdd:PTZ00121  1149 EDAKRVEIARKAEDARKAEEARKAEDAKKAEAARKAEEVRKAEELRKAEDARKAEAARKAEEERKAEEARKAEDAKkaea 1228

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039768907  239 ------VTKKGSTGKDSASESGGEKAGSKKEAKVTKKGSTGKDSASESGgEKAGSKKEAKVTKKGSTGKDSASESGGEKA 312
Cdd:PTZ00121  1229 vkkaeeAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEA-RKADELKKAEEKKKADEAKKAEEKKKADEA 1307

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039768907  313 gsKKEAKVTKKGSKSKDSASESGGEKAGSKKEAKVTKKGSTGKDSASESGGEKA-GSKKEAKATKKGSKSKDSASESGGE 391
Cdd:PTZ00121  1308 --KKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAeAAEEKAEAAEKKKEEAKKKADAAKK 1385

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039768907  392 KAGSKKEAKATKKGSKSKDSASESGGEKAGSKKEAKATKKGSKDKTSiSESGSEKAGSKKEAKTTKKGSKDKVSAtESGG 471
Cdd:PTZ00121  1386 KAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKK-ADEAKKKAEEAKKADEAKKKAEEAKKA-EEAK 1463

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1039768907  472 EKAGSKKEAKATKKGSKDKVSGTESGGEKAGSKKEAKTTKKESKDKVSATE 522
Cdd:PTZ00121  1464 KKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADE 1514
PTZ00121 PTZ00121
MAEBL; Provisional
 108-495 1.66e-09

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 61.31  E-value: 1.66e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039768907  108 ESKSVGTHKSLASEKTKKEVKMKKDGFEAKEKTALKTDKEGSPkpAKKNIPRDSQKDKGRVSSDSEGEKAGVKKGSKKVK 187
Cdd:PTZ00121  1333 AAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEE--AKKKADAAKKKAEEKKKADEAKKKAEEDKKKADEL 1410

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039768907  188 NTPKGKDSASESEGEKAGSKKEAKVTKKGSTGKDSTSESGgEKAGSKKEAKVTKKGSTGKDSASESGgEKAGSKKEAKVT 267
Cdd:PTZ00121  1411 KKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAK-KKAEEAKKAEEAKKKAEEAKKADEAK-KKAEEAKKADEA 1488

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039768907  268 KKGSTGKDSASESGGEKAGSKKEAKVTKKGSTGKDSASESGGEKAGSKKEAKVTKKGSKSKDSASESGGEKAGSKKEAKV 347
Cdd:PTZ00121  1489 KKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEE 1568

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039768907  348 TKKGSTGKDSASESGGE--KAGSKKEAKATKKGSKSKDSASESGGEKAGSKKEAKATKKGSKSKDSASESGGEKAGSKKE 425
Cdd:PTZ00121  1569 AKKAEEDKNMALRKAEEakKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKK 1648

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1039768907  426 AKATKKGSKDKTSISESGSEKAGS-KKEAKTTKKGSKDKVSATESGGEKAGSKKEAKATKKGSKDKVSGTE 495
Cdd:PTZ00121  1649 AEELKKAEEENKIKAAEEAKKAEEdKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAE 1719
PTZ00121 PTZ00121
MAEBL; Provisional
 193-484 2.33e-09

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 60.93  E-value: 2.33e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039768907  193 KDSASESEGEKAGSKKEAKVTKKGSTGKDSTSESGGEKA-GSKKEAKVTKKGSTGKDSASESGGEKAGSKKEAKVTKKGS 271
Cdd:PTZ00121  1321 KKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAeAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKA 1400

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039768907  272 TGKDSASESGGEKAGSKKEAKVTKKGSTGKDSASESgGEKAGSKKEAKVTKKGSKSKDSAsESGGEKAGSKKEAKVTKKG 351
Cdd:PTZ00121  1401 EEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEA-KKKAEEAKKADEAKKKAEEAKKA-EEAKKKAEEAKKADEAKKK 1478

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039768907  352 STGKDSASESGGEKAGSKKEAKATKKGSKSKDSASES-GGEKAGSKKEAKATKKGSKSKDSASESGGEKAGSKKEAKATK 430
Cdd:PTZ00121  1479 AEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAkKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELK 1558

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1039768907  431 KGSKDKTSISESGSE--KAGSKKEAKTTKKGSKDKVSATESGGEKAGSKKEAKATK 484
Cdd:PTZ00121  1559 KAEEKKKAEEAKKAEedKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKK 1614
PTZ00121 PTZ00121
MAEBL; Provisional
 135-522 6.37e-09

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 59.38  E-value: 6.37e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039768907  135 EAKEKTALKTDKEGSPKPAKKNIPRDSQKDKGRVSSDS-EGEKAGVKKGSKKVKNTPKGKDSASESEGEKAGSKKEAKVT 213
Cdd:PTZ00121  1102 EAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDArKAEEARKAEDAKRVEIARKAEDARKAEEARKAEDAKKAEAA 1181

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039768907  214 KKGSTGKDSTSESGGEKAGSKKEAKVTKKGSTGKDSASESGGEKAGSKKEAKVTKKGSTGKDSASESGGEKAGSKKEAKV 293
Cdd:PTZ00121  1182 RKAEEVRKAEELRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEAR 1261

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039768907  294 TKKGSTGKDSASESGGEKAGSKKEAKVTKKGSKSKDSASESGGEKAgsKKEAKVTKKGSTGKDSASESGGEKAGSKKEAK 373
Cdd:PTZ00121  1262 MAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEA--KKKAEEAKKADEAKKKAEEAKKKADAAKKKAE 1339

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039768907  374 ATKKGSKSKDSASESGGEKA-GSKKEAKATKKGSKSKDSASESGGEKAGSKKEA-KATKKGSKDKTSISESgSEKAGSKK 451
Cdd:PTZ00121  1340 EAKKAAEAAKAEAEAAADEAeAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKAdEAKKKAEEDKKKADEL-KKAAAAKK 1418

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1039768907  452 EAKTTKKGSKDKVSATESgGEKAGSKKEAKATKKGSKDKvSGTESGGEKAGSKKEAKTTKKESKDKVSATE 522
Cdd:PTZ00121  1419 KADEAKKKAEEKKKADEA-KKKAEEAKKADEAKKKAEEA-KKAEEAKKKAEEAKKADEAKKKAEEAKKADE 1487
PTZ00121 PTZ00121
MAEBL; Provisional
 135-573 4.60e-07

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 53.61  E-value: 4.60e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039768907  135 EAKEKTALKTDKEGSPKPAKKNIPRDSQKDKGRVSSDSEGEKAGVKKGSKKVKNTPKGKDSASESEGEKAGSKKEAKVTK 214
Cdd:PTZ00121  1285 KAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEE 1364

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039768907  215 KGSTGKDSTSESGGEKAGSKKEAKVTKKGSTGKDSASESggekagsKKEAKVTKKGSTGKDSASESGgEKAGSKKEAKVT 294
Cdd:PTZ00121  1365 KAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEED-------KKKADELKKAAAAKKKADEAK-KKAEEKKKADEA 1436

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039768907  295 KKGSTGKDSASESGgEKAGSKKEAKVTKKGSKSKDSASESGgEKAGSKKEAKVTKKGSTGKDSASESGGEKAGSKKEAKA 374
Cdd:PTZ00121  1437 KKKAEEAKKADEAK-KKAEEAKKAEEAKKKAEEAKKADEAK-KKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADE 1514

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039768907  375 TKKGSKSKDSASESGGEKAGSKKEAKATKKGSKSKDSASESGGEKAGSKKEAKATKKGSKDKTSISESGSE--KAGSKKE 452
Cdd:PTZ00121  1515 AKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEakKAEEARI 1594

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039768907  453 AKTTKKGSKDKVSATESGGEKAGSKKEAKATKKGSKDKVSGTESGGEKAGSKKEAKTTKKESKDKVSATESGGEKAGSKK 532
Cdd:PTZ00121  1595 EEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDK 1674

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|.
gi 1039768907  533 EAKDDKKDATSSQETllstAADKDGKKKEEKPVKQSSKSKD 573
Cdd:PTZ00121  1675 KKAEEAKKAEEDEKK----AAEALKKEAEEAKKAEELKKKE 1711
PTZ00121 PTZ00121
MAEBL; Provisional
 120-590 1.10e-06

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 52.07  E-value: 1.10e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039768907  120 SEKTKKEVKMKKDGFEAKEKTALKTDKEGSPKPAKKNIPRDSQKDKGRVSSDSEGEKAGVKKGskkvkntpKGKDSASES 199
Cdd:PTZ00121  1298 AEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAE--------AAEEKAEAA 1369

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039768907  200 EGEKAGSKKEAKVTKKGSTGKDSTSESGGEKAGSKKEAKVTKKGSTGKDSASESGgEKAGSKKEAKVTKKGSTGKDSASE 279
Cdd:PTZ00121  1370 EKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAK-KKAEEKKKADEAKKKAEEAKKADE 1448

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039768907  280 SGgEKAGSKKEAKVTKKGSTGKDSASESGgEKAGSKKEAKVTKKGSKSKDSASESGGEKAGSKKEAKVTKKGSTGKDSAS 359
Cdd:PTZ00121  1449 AK-KKAEEAKKAEEAKKKAEEAKKADEAK-KKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADE 1526

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039768907  360 ESGGEKAGSKKEAKATKKGSKSKDSASESGGEKAGSKKEAKATKKGSKSKDSASESGGE--KAGSKKEAKATKKGSKDKT 437
Cdd:PTZ00121  1527 AKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEakKAEEARIEEVMKLYEEEKK 1606

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039768907  438 SISESGSEKAGSKKEAKTTKKGSKDKVSATESGGEKAGSKKEAKATKKGSKD-KVSGTESGGEKAGSKKEAKTTKKESKD 516
Cdd:PTZ00121  1607 MKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEEnKIKAAEEAKKAEEDKKKAEEAKKAEED 1686

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1039768907  517 KVSATESGGEKAgskKEAKDDKKDATSSQETLLSTAADKDGKKKEEKPVKQSSKSKDTVKDSAsekgDEKKEDK 590
Cdd:PTZ00121  1687 EKKAAEALKKEA---EEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKA----EEAKKDE 1753
2A1904 TIGR00927
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ...
 191-452 1.60e-06

K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273344 [Multi-domain]  Cd Length: 1096  Bit Score: 51.53  E-value: 1.60e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039768907  191 KGKDSASESEGEKAGSKKEAKVTKKGSTGKdstsESGGEKAGSKKEAKVTKKGSTGkDSASESGGEKA--GSKKEAKVTK 268
Cdd:TIGR00927  632 KGDVAEAEHTGERTGEEGERPTEAEGENGE----ESGGEAEQEGETETKGENESEG-EIPAERKGEQEgeGEIEAKEADH 706

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039768907  269 KGSTGKDSASESGGEKAGSKKEAKVTKKGSTGKDSASESGGEKAGSKKEAKVTKKGSKSKDSASESGGEKAGSKKEAKVT 348
Cdd:TIGR00927  707 KGETEAEEVEHEGETEAEGTEDEGEIETGEEGEEVEDEGEGEAEGKHEVETEGDRKETEHEGETEAEGKEDEDEGEIQAG 786

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039768907  349 KKGSTGKDSASESGGEKAGSKKEAKATKKGSKSKDSASESGGEKAGSKKEAKATKKG-SKSKDSASESGGEKAGSKKEAK 427
Cdd:TIGR00927  787 EDGEMKGDEGAEGKVEHEGETEAGEKDEHEGQSETQADDTEVKDETGEQELNAENQGeAKQDEKGVDGGGGSDGGDSEEE 866

                          250       260
                   ....*....|....*....|....*
gi 1039768907  428 ATKKGSKDKTSISESGSEKAGSKKE 452
Cdd:TIGR00927  867 EEEEEEEEEEEEEEEEEEEEEEENE 891
PTZ00121 PTZ00121
MAEBL; Provisional
 108-485 2.82e-06

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 50.91  E-value: 2.82e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039768907  108 ESKSVGTHKSLASEKTKKEVKMKKDGFEAKEKTALKTDKEGSPKPAKKNIPRDSQKDKGRVSSDSEGEKAGVKKGSKKVK 187
Cdd:PTZ00121  1382 AAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEE 1461

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039768907  188 NTPKGKDSASESEGEK-AGSKKEAKVTKKGSTGKDSTSESGGEKAGSKKEAKVTKKGSTGKDSASESGGEKAGSKKEAKV 266
Cdd:PTZ00121  1462 AKKKAEEAKKADEAKKkAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKK 1541

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039768907  267 TKKGSTGKDSASESGGEKAGSKKEAKVTKKGSTGKDSASESGGE----------------KAGSKKEAKVTKKGSKSKDS 330
Cdd:PTZ00121  1542 AEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEakkaeearieevmklyEEEKKMKAEEAKKAEEAKIK 1621

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039768907  331 ASESGGEKAGSKKEAKVTKKGSTGKDSASESGGEKAGSK-KEAKATKKGSKSKDSASESGGEKAGSKKEAKATKKGSKSK 409
Cdd:PTZ00121  1622 AEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKiKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEA 1701

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1039768907  410 DSASESGGEKAGSKKEAKATKKGSK-DKTSISESGSEKAGSKKEAKTTKKGSKDKVSATESGGEKAGSKKEAKATKK 485
Cdd:PTZ00121  1702 KKAEELKKKEAEEKKKAEELKKAEEeNKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKE 1778
PTZ00121 PTZ00121
MAEBL; Provisional
 153-490 3.89e-06

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 50.52  E-value: 3.89e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039768907  153 AKKNIPRDSQKDKGRVSSDSEGEKAGVKKGSKKV-KNTPKGKDSASESEGEKAGSKKEAKVTKKGSTGKDSTSESGGEKA 231
Cdd:PTZ00121  1096 AFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKaEEARKAEDARKAEEARKAEDAKRVEIARKAEDARKAEEARKAEDA 1175

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039768907  232 GSKKEAKVTKKGSTGKDSASESGGEKAGSKKEAKVTKKGSTGKDSASESGGEKAGSKKEAKvtKKGSTGKDSASESGGEK 311
Cdd:PTZ00121  1176 KKAEAARKAEEVRKAEELRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAK--KDAEEAKKAEEERNNEE 1253

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039768907  312 AGSKKEAKVTKKGSKSKDSASESGgEKAGSKKEAKVTKKGSTGKDSASESGGEKAgsKKEAKATKKGSKSKDSASESGGE 391
Cdd:PTZ00121  1254 IRKFEEARMAHFARRQAAIKAEEA-RKADELKKAEEKKKADEAKKAEEKKKADEA--KKKAEEAKKADEAKKKAEEAKKK 1330

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039768907  392 KAGSKKEAKATKKGSKSKDSASESGGEKA-GSKKEAKATKKGSKDKTSISESGSEKAGSKKEA-KTTKKGSKDKVSATES 469
Cdd:PTZ00121  1331 ADAAKKKAEEAKKAAEAAKAEAEAAADEAeAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKAdEAKKKAEEDKKKADEL 1410

                          330       340
                   ....*....|....*....|.
gi 1039768907  470 GGEKAGSKKEAKATKKGSKDK 490
Cdd:PTZ00121  1411 KKAAAAKKKADEAKKKAEEKK 1431
PTZ00108 PTZ00108
DNA topoisomerase 2-like protein; Provisional
 208-425 1.75e-05

DNA topoisomerase 2-like protein; Provisional


Pssm-ID: 240271 [Multi-domain]  Cd Length: 1388  Bit Score: 48.12  E-value: 1.75e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039768907  208 KEAKVTKKGSTGKDSTSESGGEKAGSKKEAKVTKKGSTGKDSASESGGEKAGSKKEAKVTKKGSTGKDSASESGGEKAGS 287
Cdd:PTZ00108  1154 KEQRLKSKTKGKASKLRKPKLKKKEKKKKKSSADKSKKASVVGNSKRVDSDEKRKLDDKPDNKKSNSSGSDQEDDEEQKT 1233

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039768907  288 KKEAKVTKKGSTGKDSASESGgeKAGSKKEAKVTKKGSKSKDSASESGGEKAGSKKEAKVTKKGSTGKDSASESG----- 362
Cdd:PTZ00108  1234 KPKKSSVKRLKSKKNNSSKSS--EDNDEFSSDDLSKEGKPKNAPKRVSAVQYSPPPPSKRPDGESNGGSKPSSPTkkkvk 1311

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039768907  363 -------GEKAGSKKEAKATKKGSKSKDSASESGGEKAGSKKEAKATKKGSKSKDSASESGGEKAGSKKE 425
Cdd:PTZ00108  1312 krlegslAALKKKKKSEKKTARKKKSKTRVKQASASQSSRLLRRPRKKKSDSSSEDDDDSEVDDSEDEDD 1381
PRK05901 PRK05901
RNA polymerase sigma factor; Provisional
 298-520 7.60e-05

RNA polymerase sigma factor; Provisional


Pssm-ID: 235640 [Multi-domain]  Cd Length: 509  Bit Score: 45.76  E-value: 7.60e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039768907 298 STGKDSASESGGEKAGSKKEAKVTKKGSKSKDSASESGGEKAGSKKEAKVTKKGSTGKDSASESGGEKAGSKKEAKATKK 377
Cdd:PRK05901    2 TTASTKAELAAEEEAKKKLKKLAAKSKSKGFITKEEIKEALESKKKTPEQIDQVLIFLSGMVKDTDDATESDIPKKKTKT 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039768907 378 GSKSKDSasesggeKAGSKKEAKATKKGSKSKDSASESGGEKAGSKKEAKATKKGSKDKTSISESGSEKAGSKKEAKTTK 457
Cdd:PRK05901   82 AAKAAAA-------KAPAKKKLKDELDSSKKAEKKNALDKDDDLNYVKDIDVLNQADDDDDDDDDDDLDDDDIDDDDDDE 154

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1039768907 458 KGSKDkvSATESGGEKAGSKKEAKATKKGSKDKVSGTESGGEKAGSKKEAKTTKKESKDKVSA 520
Cdd:PRK05901  155 DDDED--DDDDDVDDEDEEKKEAKELEKLSDDDDFVWDEDDSEALRQARKDAKLTATADPVKA 215
MSCRAMM_ClfA NF033609
MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial ...
 145-503 2.27e-04

MSCRAMM family adhesin clumping factor ClfA; Clumping factor A is an MSCRAMM (Microbial Surface Components Recognizing Adhesive Matrix Molecules). It is heavily studied in Staphylococcus aureus both for its biological role in adhesion and for its potential for vaccination. Features of the sequence, but also of other MSCRAMM adhesins, include a long run of Ser-Asp dipeptide repeats and a C-terminal cell wall anchoring LPXTG motif.


Pssm-ID: 468110 [Multi-domain]  Cd Length: 934  Bit Score: 44.51  E-value: 2.27e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039768907 145 DKEGSPKPAKKNIPRDSQKDKGRVSSDSE-GEKAGVKKGSKKVKNTPKGKDSASESE-GEKAGSKKEAKVTKKGSTGKDS 222
Cdd:NF033609  549 DEPGEIEPIPEDSDSDPGSDSGSDSSNSDsGSDSGSDSTSDSGSDSASDSDSASDSDsASDSDSASDSDSASDSDSASDS 628

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039768907 223 TSESGGEKAGSKKEAKVTKKGSTGKDSASESGGEKAGSKKEAKVTKKGSTGKDSASESGGEKAGSKKEAKVTKKGSTGKD 302
Cdd:NF033609  629 DSASDSDSASDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 708

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039768907 303 SASESGGEKAGSKKEAKVTKKGSKSKDSASESGGEKAGSKKEAKVTKKGSTGKDSASESGGEKAGSKKEAKATKKGSKSK 382
Cdd:NF033609  709 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS 788

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039768907 383 DSASESGGEKAGSKKEAKATKKGSKSKDSASESGGEKAGSKKEAKATKKGSKDKTSISESGSEKAGSKKEAKTTKKGSKD 462
Cdd:NF033609  789 DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSESDSNSDSESGS 868

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|.
gi 1039768907 463 KVSATESGGEKAGSKKEAKATKKGSKDKVSGTESGGEKAGS 503
Cdd:NF033609  869 NNNVVPPNSPKNGTNASNKNEAKDSKEPLPDTGSEDEANTS 909
2A1904 TIGR00927
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ...
 149-425 3.53e-04

K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273344 [Multi-domain]  Cd Length: 1096  Bit Score: 43.83  E-value: 3.53e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039768907  149 SPKPAKKNIPRDSQKDKGRVSSDSEGEKAGVKKGSKKVKNTPKGKdsasESEGEKAGSKKEAKVTKKGSTGkDSTSESGG 228
Cdd:TIGR00927  617 SRRPVAKVMALGDLSKGDVAEAEHTGERTGEEGERPTEAEGENGE----ESGGEAEQEGETETKGENESEG-EIPAERKG 691

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039768907  229 EKA--GSKKEAKVTKKGSTGKDSASESGGEKAGSKKEAKVTKKGSTGKDSASESGGEKAGSKKEAKVTKKGSTGKDSASE 306
Cdd:TIGR00927  692 EQEgeGEIEAKEADHKGETEAEEVEHEGETEAEGTEDEGEIETGEEGEEVEDEGEGEAEGKHEVETEGDRKETEHEGETE 771

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039768907  307 SGGEKAGSKKEAKVTKKGSKSKDSASESGGEKAGSKKEAKVTKKGSTGKDSASESGGEKAGSKKEAKATKKG-SKSKDSA 385
Cdd:TIGR00927  772 AEGKEDEDEGEIQAGEDGEMKGDEGAEGKVEHEGETEAGEKDEHEGQSETQADDTEVKDETGEQELNAENQGeAKQDEKG 851

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|
gi 1039768907  386 SESGGEKAGSKKEAKATKKGSKSKDSASESGGEKAGSKKE 425
Cdd:TIGR00927  852 VDGGGGSDGGDSEEEEEEEEEEEEEEEEEEEEEEEEEENE 891
2A1904 TIGR00927
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ...
 132-371 6.57e-04

K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273344 [Multi-domain]  Cd Length: 1096  Bit Score: 43.06  E-value: 6.57e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039768907  132 DGFEAKEKTALKTDKEGSPKPAKKNIPRDSQKDKGRV-SSDSEGEKAGVKKGSKKVKNTPKGKDSASESEGEKAGSKKEA 210
Cdd:TIGR00927  634 DVAEAEHTGERTGEEGERPTEAEGENGEESGGEAEQEgETETKGENESEGEIPAERKGEQEGEGEIEAKEADHKGETEAE 713

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039768907  211 KVTKKGSTGKDSTSESG-GEKAGSKKEAKVTKKGSTGKDSASESGGEKAGSKKEAKVTKKGSTGKDSA---SESGGEKAG 286
Cdd:TIGR00927  714 EVEHEGETEAEGTEDEGeIETGEEGEEVEDEGEGEAEGKHEVETEGDRKETEHEGETEAEGKEDEDEGeiqAGEDGEMKG 793

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039768907  287 SKKEAKVTKKGSTGKDSASESGGEKAGSKKEAKVTKKGSKSKDSASESGGEKAGSKKEAKvTKKGSTGKDSASESGGEKA 366
Cdd:TIGR00927  794 DEGAEGKVEHEGETEAGEKDEHEGQSETQADDTEVKDETGEQELNAENQGEAKQDEKGVD-GGGGSDGGDSEEEEEEEEE 872


                   ....*
gi 1039768907  367 GSKKE 371
Cdd:TIGR00927  873 EEEEE 877
2A1904 TIGR00927
K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying ...
 237-499 8.20e-04

K+-dependent Na+/Ca+ exchanger; [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 273344 [Multi-domain]  Cd Length: 1096  Bit Score: 42.68  E-value: 8.20e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039768907  237 AKVTKKG--STGKDSASESGGEKAGSKKEAKVTKKGSTGKdsasESGGEKAGSKKEAKVTKKGSTGkDSASESGGEKAG- 313
Cdd:TIGR00927  622 AKVMALGdlSKGDVAEAEHTGERTGEEGERPTEAEGENGE----ESGGEAEQEGETETKGENESEG-EIPAERKGEQEGe 696

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039768907  314 --SKKEAKVTKKGSKSKDSASESGGEKAGSKKEAKvTKKGSTGKDSASESGGEKAGSKKEAKATKKGSKSKDSASESGGE 391
Cdd:TIGR00927  697 geIEAKEADHKGETEAEEVEHEGETEAEGTEDEGE-IETGEEGEEVEDEGEGEAEGKHEVETEGDRKETEHEGETEAEGK 775

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039768907  392 KAGSKKEAKATKKGSKSKDSASESGGEKAGSKKEAKATKKGSKDKTSISESGSEKAGSKKEAKTTKKGskdkvsatesgg 471
Cdd:TIGR00927  776 EDEDEGEIQAGEDGEMKGDEGAEGKVEHEGETEAGEKDEHEGQSETQADDTEVKDETGEQELNAENQG------------ 843

                          250       260
                   ....*....|....*....|....*...
gi 1039768907  472 ekagskkEAKATKKGSKDKvsGTESGGE 499
Cdd:TIGR00927  844 -------EAKQDEKGVDGG--GGSDGGD 862
PRK13808 PRK13808
adenylate kinase; Provisional
 354-485 1.05e-03

adenylate kinase; Provisional


Pssm-ID: 172341 [Multi-domain]  Cd Length: 333  Bit Score: 41.80  E-value: 1.05e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039768907 354 GKDSASESGGEKAGSKKEAKATKKGSKSKDSASESGGEKAGSKKEAKATKKGSKSKDSASESGGE---KAGSKKEAKATK 430
Cdd:PRK13808  197 ANAKKAAKTPAAKSGAKKASAKAKSAAKKVSKKKAAKTAVSAKKAAKTAAKAAKKAKKTAKKALKkaaKAVKKAAKKAAK 276

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1039768907 431 KGSKDKTSISESGSEKAGSKKEAKTTKKGSKDKVSATESGGEKAGSKKEAKATKK 485
Cdd:PRK13808  277 AAAKAAKGAAKATKGKAKAKKKAGKKAAAGSKAKATAKAPKRGAKGKKAKKVTKK 331
PTZ00108 PTZ00108
DNA topoisomerase 2-like protein; Provisional
 369-579 1.06e-03

DNA topoisomerase 2-like protein; Provisional


Pssm-ID: 240271 [Multi-domain]  Cd Length: 1388  Bit Score: 42.34  E-value: 1.06e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039768907  369 KKEAKATKKGSKSKDSASESGGEKAGSKKEAKATKKGSKSKDSASesggekaGSKKEAKATKKGSKDKTSISESGSEKAG 448
Cdd:PTZ00108  1146 EVEEKEIAKEQRLKSKTKGKASKLRKPKLKKKEKKKKKSSADKSK-------KASVVGNSKRVDSDEKRKLDDKPDNKKS 1218

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039768907  449 SKKEAKTTKKGSKDKVSATESGGEKAGSKKEAKATKKGSKDKVSGTESGGEKAGSKKEAKTTKKESKDKVSATESGGEKA 528
Cdd:PTZ00108  1219 NSSGSDQEDDEEQKTKPKKSSVKRLKSKKNNSSKSSEDNDEFSSDDLSKEGKPKNAPKRVSAVQYSPPPPSKRPDGESNG 1298

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1039768907  529 GSKKEAKDDKKDatssQETLLSTAADKDGKKKEEKPVKQSSKSKDTVKDSA 579
Cdd:PTZ00108  1299 GSKPSSPTKKKV----KKRLEGSLAALKKKKKSEKKTARKKKSKTRVKQAS 1345
PRK05901 PRK05901
RNA polymerase sigma factor; Provisional
 249-459 1.26e-03

RNA polymerase sigma factor; Provisional


Pssm-ID: 235640 [Multi-domain]  Cd Length: 509  Bit Score: 41.90  E-value: 1.26e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039768907 249 SASESGGEKAGSKKEAKVTKKGSTGKDSASESGGEKAGSKKE----AKVTKKGSTGKDSASESGGEKAGSKKEAKVTKKG 324
Cdd:PRK05901    6 TKAELAAEEEAKKKLKKLAAKSKSKGFITKEEIKEALESKKKtpeqIDQVLIFLSGMVKDTDDATESDIPKKKTKTAAKA 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039768907 325 SKSKDSASESG-GEKAGSKKEAKVTKKGSTGKDSASESGGEKAGSKKEAKATKKGSKSKDSASESGGEKAGSKKEAKATK 403
Cdd:PRK05901   86 AAAKAPAKKKLkDELDSSKKAEKKNALDKDDDLNYVKDIDVLNQADDDDDDDDDDDLDDDDIDDDDDDEDDDEDDDDDDV 165

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1039768907 404 KgskskdsasesggEKAGSKKEAKaTKKGSKDKTSISESGSEKAGSKKEAKTTKKG 459
Cdd:PRK05901  166 D-------------DEDEEKKEAK-ELEKLSDDDDFVWDEDDSEALRQARKDAKLT 207
PRK13808 PRK13808
adenylate kinase; Provisional
 300-431 2.81e-03

adenylate kinase; Provisional


Pssm-ID: 172341 [Multi-domain]  Cd Length: 333  Bit Score: 40.26  E-value: 2.81e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039768907 300 GKDSASESGGEKAGSKKEAKVTKKGSKSKDSASESGGEKAGSKKEAKVTKKGSTGKDSASESGGE---KAGSKKEAKATK 376
Cdd:PRK13808  197 ANAKKAAKTPAAKSGAKKASAKAKSAAKKVSKKKAAKTAVSAKKAAKTAAKAAKKAKKTAKKALKkaaKAVKKAAKKAAK 276

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1039768907 377 KGSKSKDSASESGGEKAGSKKEAKATKKGSKSKDSASESGGEKAGSKKEAKATKK 431
Cdd:PRK13808  277 AAAKAAKGAAKATKGKAKAKKKAGKKAAAGSKAKATAKAPKRGAKGKKAKKVTKK 331
PRK05901 PRK05901
RNA polymerase sigma factor; Provisional
 222-432 6.78e-03

RNA polymerase sigma factor; Provisional


Pssm-ID: 235640 [Multi-domain]  Cd Length: 509  Bit Score: 39.59  E-value: 6.78e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039768907 222 STSESGGEKAGSKKEAKVTKKGSTGKDSASESGGEKAGSKKE----AKVTKKGSTGKDSASESGGEKAGSKKEAKVTKKG 297
Cdd:PRK05901    6 TKAELAAEEEAKKKLKKLAAKSKSKGFITKEEIKEALESKKKtpeqIDQVLIFLSGMVKDTDDATESDIPKKKTKTAAKA 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039768907 298 STGKDSASESG-GEKAGSKKEAKVTKKGSKSKDSASESGGEKAGSKKEAKVTKKGSTGKDSASESGGEKAGSKKEAKATK 376
Cdd:PRK05901   86 AAAKAPAKKKLkDELDSSKKAEKKNALDKDDDLNYVKDIDVLNQADDDDDDDDDDDLDDDDIDDDDDDEDDDEDDDDDDV 165

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1039768907 377 KgskskdsasesggEKAGSKKEAKaTKKGSKSKDSASESGGEKAGSKKEAKATKKG 432
Cdd:PRK05901  166 D-------------DEDEEKKEAK-ELEKLSDDDDFVWDEDDSEALRQARKDAKLT 207
PRK13108 PRK13108
prolipoprotein diacylglyceryl transferase; Reviewed
 344-495 7.68e-03

prolipoprotein diacylglyceryl transferase; Reviewed


Pssm-ID: 237284 [Multi-domain]  Cd Length: 460  Bit Score: 39.19  E-value: 7.68e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039768907 344 EAKVTKKGSTGKDSASESGGEKAGSKK---EAKATKKGSKSKDSASESG------GEKAGSKKEA-KATKKGSKSKDSAS 413
Cdd:PRK13108  302 ELAAAAVASAASAVGPVGPGEPNQPDDvaeAVKAEVAEVTDEVAAESVVqvadrdGESTPAVEETsEADIEREQPGDLAG 381

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039768907 414 ESGGEKAGSKKEAKATKKGSKDKTSISESGSEKAGSKKEAKTTKKGSKDKVSATESGGEKAGSKkeakatKKGSKDKVSG 493
Cdd:PRK13108  382 QAPAAHQVDAEAASAAPEEPAALASEAHDETEPEVPEKAAPIPDPAKPDELAVAGPGDDPAEPD------GIRRQDDFSS 455


                  ..
gi 1039768907 494 TE 495
Cdd:PRK13108  456 RR 457
valS PRK14900
valyl-tRNA synthetase; Provisional
 303-451 7.88e-03

valyl-tRNA synthetase; Provisional


Pssm-ID: 237855 [Multi-domain]  Cd Length: 1052  Bit Score: 39.59  E-value: 7.88e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039768907  303 SASESGGEKAGSKKEAKVTKKGSKSKDSASESGGEKAGS-KKEAKVTKKGSTGKDSASESGGEK--AGSKKEAKATKKGS 379
Cdd:PRK14900   906 SEANSARRDTMEIQNEQKPTQDGPAAEAQPAQENTVVESaEKAVAAVSEAAQQAATAVASGIEKvaEAVRKTVRRSVKKA 985

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1039768907  380 KSKDSASESGGEKAGSKKEAKATKKGSKsKDSASESGGEKAGSKKEAK--ATKKGSKdktsiseSGSEKAGSKK 451
Cdd:PRK14900   986 AATRAAMKKKVAKKAPAKKAAAKKAAAK-KAAAKKKVAKKAPAKKVARkpAAKKAAK-------KPARKAAGRK 1051
PTZ00449 PTZ00449
104 kDa microneme/rhoptry antigen; Provisional
 151-330 9.20e-03

104 kDa microneme/rhoptry antigen; Provisional


Pssm-ID: 185628 [Multi-domain]  Cd Length: 943  Bit Score: 39.29  E-value: 9.20e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039768907 151 KPAKKNIPRDSQKDKGRVSSDSEGEKAGVKKgskkvkntPKGKDSASESEGEKaGSKKEAKVTKKGSTGKDSTSESGGEK 230
Cdd:PTZ00449  490 KKSKKKLAPIEEEDSDKHDEPPEGPEASGLP--------PKAPGDKEGEEGEH-EDSKESDEPKEGGKPGETKEGEVGKK 560

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039768907 231 AGSKKEAKVTKKGSTGKDSASESGGEKAGSKKEAKVTKKGSTGKDSASESGGEKAGSKKEAKVTKKGSTGKDSASESGGE 310
Cdd:PTZ00449  561 PGPAKEHKPSKIPTLSKKPEFPKDPKHPKDPEEPKKPKRPRSAQRPTRPKSPKLPELLDIPKSPKRPESPKSPKRPPPPQ 640

                         170       180
                  ....*....|....*....|..
gi 1039768907 311 KAGSKKEAKVTK--KGSKSKDS 330
Cdd:PTZ00449  641 RPSSPERPEGPKiiKSPKPPKS 662
PRK05901 PRK05901
RNA polymerase sigma factor; Provisional
 325-552 9.74e-03

RNA polymerase sigma factor; Provisional


Pssm-ID: 235640 [Multi-domain]  Cd Length: 509  Bit Score: 38.82  E-value: 9.74e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039768907 325 SKSKDSASESGGEKAGSKKEAKVTKKGSTGKDSASEsggekagskKEAKATKKGSKSKDSAsesggekagsKKEAKATKK 404
Cdd:PRK05901    1 MTTASTKAELAAEEEAKKKLKKLAAKSKSKGFITKE---------EIKEALESKKKTPEQI----------DQVLIFLSG 61

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1039768907 405 GSKSKDSASESGGEKAGSKKEAKATKKGSKDKTSISEsgsEKAGSKKEAKTTKKGSKDKVSATESGGEKAGSKKEAKATK 484
Cdd:PRK05901   62 MVKDTDDATESDIPKKKTKTAAKAAAAKAPAKKKLKD---ELDSSKKAEKKNALDKDDDLNYVKDIDVLNQADDDDDDDD 138

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1039768907 485 KGSKDKVSGTESGGEKAGSKKEAKTTKKESKDKVSATESGGEKAGSKKEAKDDKKDATSSQETLLSTA 552
Cdd:PRK05901  139 DDDLDDDDIDDDDDDEDDDEDDDDDDVDDEDEEKKEAKELEKLSDDDDFVWDEDDSEALRQARKDAKL 206
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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