|
Name |
Accession |
Description |
Interval |
E-value |
| LRR_RI |
cd00116 |
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ... |
784-1110 |
1.22e-78 |
|
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).
:
Pssm-ID: 238064 [Multi-domain] Cd Length: 319 Bit Score: 261.14 E-value: 1.22e-78
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196069858 784 LTRYLKRLKLGSLRAGRLLELLHCaheTQEPGIWEHVVHQlpGHLSFLGTRLTPP--DVHVLGRALETASqdfslDLRQT 861
Cdd:cd00116 1 LQLSLKGELLKTERATELLPKLLC---LQVLRLEGNTLGE--EAAKALASALRPQpsLKELCLSLNETGR-----IPRGL 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196069858 862 GIEPSGLGNLVGLSCVTSFRAALS-DTMVLWESLRH---QGEPQLLQAAEEKfTLEPFKAKSPKDV-EDLDSLVQTQRLR 936
Cdd:cd00116 71 QSLLQGLTKGCGLQELDLSDNALGpDGCGVLESLLRsssLQELKLNNNGLGD-RGLRLLAKGLKDLpPALEKLVLGRNRL 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196069858 937 N--PSEDAALDLPAIRDLKKLEFALGPvLGPQAFPTLVKILPAFSSLQHLDLDSlseNKIGDEGVSRLAATFTQLKVLET 1014
Cdd:cd00116 150 EgaSCEALAKALRANRDLKELNLANNG-IGDAGIRALAEGLKANCNLEVLDLNN---NGLTDEGASALAETLASLKSLEV 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196069858 1015 LNLSQNSITDVGACKLAEALPALAKSLLRLsSLYNNCICDAGARSLAQVLPDMVSLRVMDVQFNKFTAAGAQQLASSLqK 1094
Cdd:cd00116 226 LNLGDNNLTDAGAAALASALLSPNISLLTL-SLSCNDITDDGAKDLAEVLAEKESLLELDLRGNKFGEEGAQLLAESL-L 303
|
330
....*....|....*.
gi 1196069858 1095 CPQVETLAMWTPTIPF 1110
Cdd:cd00116 304 EPGNELESLWVKDDSF 319
|
|
| NACHT |
pfam05729 |
NACHT domain; This NTPase domain is found in apoptosis proteins as well as those involved in ... |
412-583 |
7.58e-49 |
|
NACHT domain; This NTPase domain is found in apoptosis proteins as well as those involved in MHC transcription activation. This family is closely related to pfam00931.
:
Pssm-ID: 428606 [Multi-domain] Cd Length: 166 Bit Score: 170.95 E-value: 7.58e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196069858 412 QVVAVLGKAGQGKSHWARTVSQAWARGQLPQY-DFVFYVPCHCLDHPGDTYHLQDLLCPPSLQPLVMDDEVLGHIVRQPD 490
Cdd:pfam05729 1 RTVILQGEAGSGKTTLLQKLALLWAQGKLPQGfDFVFFLPCRELSRSGNARSLADLLFSQWPEPAAPVSEVWAVILELPE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196069858 491 RVLLILDAFEELEAQDGLLHGPCGPLppepcsfrGLLAGLFQRKLLRGCTLLLTARPRGR--LTQSLSKADaIFEVPSFS 568
Cdd:pfam05729 81 RLLLILDGLDELVSDLGQLDGPCPVL--------TLLSSLLRKKLLPGASLLLTVRPDALrdLRRGLEEPR-YLEVRGFS 151
|
170
....*....|....*
gi 1196069858 569 TRQAQTYMRHYFENS 583
Cdd:pfam05729 152 ESDRKQYVRKYFSDE 166
|
|
| NLRC4_HD2 super family |
cl39284 |
NLRC4 helical domain HD2; This entry represents a helical domain found in the NLRC4 protein ... |
711-813 |
1.00e-07 |
|
NLRC4 helical domain HD2; This entry represents a helical domain found in the NLRC4 protein and NOD2 protein.
The actual alignment was detected with superfamily member pfam17776:
Pssm-ID: 465499 [Multi-domain] Cd Length: 122 Bit Score: 51.52 E-value: 1.00e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196069858 711 LQCFLGAVWLAQCNEIRDKELPQYLaLTPRKKRPYDNWLEGVP-----------RFLTGLVFQPRAHCLGALMEPAVADR 779
Cdd:pfam17776 4 FQEFFAALFYVLSFKEEKSNPLKEF-FGLRKRESLKSLLDKALksknghldlflRFLFGLLNEENQRLLEGLLGCKLSSE 82
|
90 100 110
....*....|....*....|....*....|....
gi 1196069858 780 KRKVLTRYLKRLKLGSLRAGRLLELLHCAHETQE 813
Cdd:pfam17776 83 IKQELLQWIKSLIQKELSSERFLNLFHCLYELQD 116
|
|
| PHA03377 super family |
cl31823 |
EBNA-3C; Provisional |
120-348 |
1.63e-05 |
|
EBNA-3C; Provisional
The actual alignment was detected with superfamily member PHA03377:
Pssm-ID: 177614 [Multi-domain] Cd Length: 1000 Bit Score: 49.28 E-value: 1.63e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196069858 120 IERIETEEGFSESME---VPVEAGERSQKRRS----PEEHPMDPKHRKLAEPSMVPMLTGSFLMGPASISTMPYLPPALS 192
Cdd:PHA03377 517 VETTEEEESVTQPAKphrKVQDGFQRSGRRQKratpPKVSPSDRGPPKASPPVMAPPSTGPRVMATPSTGPRDMAPPSTG 596
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196069858 193 NQEPVSCHIHLEGATQTSVPPSRSSPNCLDLTIGHI----QLLPT----LPQGLWQIQgAGTGLPSVliyhgEMPQVNHV 264
Cdd:PHA03377 597 PRQQAKCKDGPPASGPHEKQPPSSAPRDMAPSVVRMflreRLLEQstgpKPKSFWEMR-AGRDGSGI-----QQEPSSRR 670
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196069858 265 IPSGSPTvsslpksPDRPCstspFAPSVADLPSMPepaltsrvneaedTTSPSPCQEGPESPIKlPKWPASverfqHSLK 344
Cdd:PHA03377 671 QPATQST-------PPRPS----WLPSVFVLPSVD-------------AGRAQPSEESHLSSMS-PTQPIS-----HEEQ 720
|
....
gi 1196069858 345 DKYQ 348
Cdd:PHA03377 721 PRYE 724
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| LRR_RI |
cd00116 |
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ... |
784-1110 |
1.22e-78 |
|
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).
Pssm-ID: 238064 [Multi-domain] Cd Length: 319 Bit Score: 261.14 E-value: 1.22e-78
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196069858 784 LTRYLKRLKLGSLRAGRLLELLHCaheTQEPGIWEHVVHQlpGHLSFLGTRLTPP--DVHVLGRALETASqdfslDLRQT 861
Cdd:cd00116 1 LQLSLKGELLKTERATELLPKLLC---LQVLRLEGNTLGE--EAAKALASALRPQpsLKELCLSLNETGR-----IPRGL 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196069858 862 GIEPSGLGNLVGLSCVTSFRAALS-DTMVLWESLRH---QGEPQLLQAAEEKfTLEPFKAKSPKDV-EDLDSLVQTQRLR 936
Cdd:cd00116 71 QSLLQGLTKGCGLQELDLSDNALGpDGCGVLESLLRsssLQELKLNNNGLGD-RGLRLLAKGLKDLpPALEKLVLGRNRL 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196069858 937 N--PSEDAALDLPAIRDLKKLEFALGPvLGPQAFPTLVKILPAFSSLQHLDLDSlseNKIGDEGVSRLAATFTQLKVLET 1014
Cdd:cd00116 150 EgaSCEALAKALRANRDLKELNLANNG-IGDAGIRALAEGLKANCNLEVLDLNN---NGLTDEGASALAETLASLKSLEV 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196069858 1015 LNLSQNSITDVGACKLAEALPALAKSLLRLsSLYNNCICDAGARSLAQVLPDMVSLRVMDVQFNKFTAAGAQQLASSLqK 1094
Cdd:cd00116 226 LNLGDNNLTDAGAAALASALLSPNISLLTL-SLSCNDITDDGAKDLAEVLAEKESLLELDLRGNKFGEEGAQLLAESL-L 303
|
330
....*....|....*.
gi 1196069858 1095 CPQVETLAMWTPTIPF 1110
Cdd:cd00116 304 EPGNELESLWVKDDSF 319
|
|
| NACHT |
pfam05729 |
NACHT domain; This NTPase domain is found in apoptosis proteins as well as those involved in ... |
412-583 |
7.58e-49 |
|
NACHT domain; This NTPase domain is found in apoptosis proteins as well as those involved in MHC transcription activation. This family is closely related to pfam00931.
Pssm-ID: 428606 [Multi-domain] Cd Length: 166 Bit Score: 170.95 E-value: 7.58e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196069858 412 QVVAVLGKAGQGKSHWARTVSQAWARGQLPQY-DFVFYVPCHCLDHPGDTYHLQDLLCPPSLQPLVMDDEVLGHIVRQPD 490
Cdd:pfam05729 1 RTVILQGEAGSGKTTLLQKLALLWAQGKLPQGfDFVFFLPCRELSRSGNARSLADLLFSQWPEPAAPVSEVWAVILELPE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196069858 491 RVLLILDAFEELEAQDGLLHGPCGPLppepcsfrGLLAGLFQRKLLRGCTLLLTARPRGR--LTQSLSKADaIFEVPSFS 568
Cdd:pfam05729 81 RLLLILDGLDELVSDLGQLDGPCPVL--------TLLSSLLRKKLLPGASLLLTVRPDALrdLRRGLEEPR-YLEVRGFS 151
|
170
....*....|....*
gi 1196069858 569 TRQAQTYMRHYFENS 583
Cdd:pfam05729 152 ESDRKQYVRKYFSDE 166
|
|
| RNA1 |
COG5238 |
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ... |
971-1123 |
3.46e-17 |
|
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];
Pssm-ID: 444072 [Multi-domain] Cd Length: 434 Bit Score: 85.61 E-value: 3.46e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196069858 971 LVKILPAFSSLQHLDLdslSENKIGDEGVSRLAATFTQLKVLETLNLSQNSITDVGACKLAEALPALaKSLLRLsSLYNN 1050
Cdd:COG5238 284 LAKALQGNTTLTSLDL---SVNRIGDEGAIALAEGLQGNKTLHTLNLAYNGIGAQGAIALAKALQEN-TTLHSL-DLSDN 358
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1196069858 1051 CICDAGARSLAQVLPDMVSLRVMDVQFNKFTAAGAQQLASSLQKcPQVETLAMWTPTIPFGVQEHLQQLDSRI 1123
Cdd:COG5238 359 QIGDEGAIALAKYLEGNTTLRELNLGKNNIGKQGAEALIDALQT-NRLHTLILDGNLIGAEAQQRLEQLLERI 430
|
|
| NLRC4_HD2 |
pfam17776 |
NLRC4 helical domain HD2; This entry represents a helical domain found in the NLRC4 protein ... |
711-813 |
1.00e-07 |
|
NLRC4 helical domain HD2; This entry represents a helical domain found in the NLRC4 protein and NOD2 protein.
Pssm-ID: 465499 [Multi-domain] Cd Length: 122 Bit Score: 51.52 E-value: 1.00e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196069858 711 LQCFLGAVWLAQCNEIRDKELPQYLaLTPRKKRPYDNWLEGVP-----------RFLTGLVFQPRAHCLGALMEPAVADR 779
Cdd:pfam17776 4 FQEFFAALFYVLSFKEEKSNPLKEF-FGLRKRESLKSLLDKALksknghldlflRFLFGLLNEENQRLLEGLLGCKLSSE 82
|
90 100 110
....*....|....*....|....*....|....
gi 1196069858 780 KRKVLTRYLKRLKLGSLRAGRLLELLHCAHETQE 813
Cdd:pfam17776 83 IKQELLQWIKSLIQKELSSERFLNLFHCLYELQD 116
|
|
| PHA03377 |
PHA03377 |
EBNA-3C; Provisional |
120-348 |
1.63e-05 |
|
EBNA-3C; Provisional
Pssm-ID: 177614 [Multi-domain] Cd Length: 1000 Bit Score: 49.28 E-value: 1.63e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196069858 120 IERIETEEGFSESME---VPVEAGERSQKRRS----PEEHPMDPKHRKLAEPSMVPMLTGSFLMGPASISTMPYLPPALS 192
Cdd:PHA03377 517 VETTEEEESVTQPAKphrKVQDGFQRSGRRQKratpPKVSPSDRGPPKASPPVMAPPSTGPRVMATPSTGPRDMAPPSTG 596
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196069858 193 NQEPVSCHIHLEGATQTSVPPSRSSPNCLDLTIGHI----QLLPT----LPQGLWQIQgAGTGLPSVliyhgEMPQVNHV 264
Cdd:PHA03377 597 PRQQAKCKDGPPASGPHEKQPPSSAPRDMAPSVVRMflreRLLEQstgpKPKSFWEMR-AGRDGSGI-----QQEPSSRR 670
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196069858 265 IPSGSPTvsslpksPDRPCstspFAPSVADLPSMPepaltsrvneaedTTSPSPCQEGPESPIKlPKWPASverfqHSLK 344
Cdd:PHA03377 671 QPATQST-------PPRPS----WLPSVFVLPSVD-------------AGRAQPSEESHLSSMS-PTQPIS-----HEEQ 720
|
....
gi 1196069858 345 DKYQ 348
Cdd:PHA03377 721 PRYE 724
|
|
| Atrophin-1 |
pfam03154 |
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ... |
143-429 |
6.99e-05 |
|
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.
Pssm-ID: 460830 [Multi-domain] Cd Length: 991 Bit Score: 47.07 E-value: 6.99e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196069858 143 SQKRRSPEEHPMDPK-----HRKLAEPSMVPMLTG-------SFLMGPASISTMPYLPP--------ALSNQEPVSCHih 202
Cdd:pfam03154 334 LQSQQPPREQPLPPAplsmpHIKPPPTTPIPQLPNpqshkhpPHLSGPSPFQMNSNLPPppalkplsSLSTHHPPSAH-- 411
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196069858 203 legatqtsVPPSRSSPNCLDLtighiQLLPTLPQGLWQIQG---AGTGLPSVLIYHGEMPQ----VNHVIPSGSPTVSSl 275
Cdd:pfam03154 412 --------PPPLQLMPQSQQL-----PPPPAQPPVLTQSQSlppPAASHPPTSGLHQVPSQspfpQHPFVPGGPPPITP- 477
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196069858 276 PKSPdrPCSTSPFAP------SVADLPSMPEPALTSRV-----------NEAEDTTSPSPCQEGPESP---IKLPKWPAS 335
Cdd:pfam03154 478 PSGP--PTSTSSAMPgiqppsSASVSSSGPVPAAVSCPlppvqikeealDEAEEPESPPPPPRSPSPEptvVNTPSHASQ 555
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196069858 336 VERFQHSLKDKYQ--VEPENLSVPMVAVELVRARLERGSNKSQERELATPDWTERQLARGGldqvlqavvDRRRPRETQV 413
Cdd:pfam03154 556 SARFYKHLDRGYNscARTDLYFMPLAGSKLAKKREEALEKAKREAEQKAREEKEREKEKEK---------ERERERERER 626
|
330
....*....|....*.
gi 1196069858 414 VAVLGKAGQGKSHWAR 429
Cdd:pfam03154 627 EAERAAKASSSSHEGR 642
|
|
| LRR_RI |
smart00368 |
Leucine rich repeat, ribonuclease inhibitor type; |
1039-1066 |
1.42e-03 |
|
Leucine rich repeat, ribonuclease inhibitor type;
Pssm-ID: 197686 [Multi-domain] Cd Length: 28 Bit Score: 37.00 E-value: 1.42e-03
10 20
....*....|....*....|....*...
gi 1196069858 1039 KSLLRLSsLYNNCICDAGARSLAQVLPD 1066
Cdd:smart00368 2 PSLRELD-LSNNKLGDEGARALAEALKD 28
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| LRR_RI |
cd00116 |
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ... |
784-1110 |
1.22e-78 |
|
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).
Pssm-ID: 238064 [Multi-domain] Cd Length: 319 Bit Score: 261.14 E-value: 1.22e-78
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196069858 784 LTRYLKRLKLGSLRAGRLLELLHCaheTQEPGIWEHVVHQlpGHLSFLGTRLTPP--DVHVLGRALETASqdfslDLRQT 861
Cdd:cd00116 1 LQLSLKGELLKTERATELLPKLLC---LQVLRLEGNTLGE--EAAKALASALRPQpsLKELCLSLNETGR-----IPRGL 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196069858 862 GIEPSGLGNLVGLSCVTSFRAALS-DTMVLWESLRH---QGEPQLLQAAEEKfTLEPFKAKSPKDV-EDLDSLVQTQRLR 936
Cdd:cd00116 71 QSLLQGLTKGCGLQELDLSDNALGpDGCGVLESLLRsssLQELKLNNNGLGD-RGLRLLAKGLKDLpPALEKLVLGRNRL 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196069858 937 N--PSEDAALDLPAIRDLKKLEFALGPvLGPQAFPTLVKILPAFSSLQHLDLDSlseNKIGDEGVSRLAATFTQLKVLET 1014
Cdd:cd00116 150 EgaSCEALAKALRANRDLKELNLANNG-IGDAGIRALAEGLKANCNLEVLDLNN---NGLTDEGASALAETLASLKSLEV 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196069858 1015 LNLSQNSITDVGACKLAEALPALAKSLLRLsSLYNNCICDAGARSLAQVLPDMVSLRVMDVQFNKFTAAGAQQLASSLqK 1094
Cdd:cd00116 226 LNLGDNNLTDAGAAALASALLSPNISLLTL-SLSCNDITDDGAKDLAEVLAEKESLLELDLRGNKFGEEGAQLLAESL-L 303
|
330
....*....|....*.
gi 1196069858 1095 CPQVETLAMWTPTIPF 1110
Cdd:cd00116 304 EPGNELESLWVKDDSF 319
|
|
| NACHT |
pfam05729 |
NACHT domain; This NTPase domain is found in apoptosis proteins as well as those involved in ... |
412-583 |
7.58e-49 |
|
NACHT domain; This NTPase domain is found in apoptosis proteins as well as those involved in MHC transcription activation. This family is closely related to pfam00931.
Pssm-ID: 428606 [Multi-domain] Cd Length: 166 Bit Score: 170.95 E-value: 7.58e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196069858 412 QVVAVLGKAGQGKSHWARTVSQAWARGQLPQY-DFVFYVPCHCLDHPGDTYHLQDLLCPPSLQPLVMDDEVLGHIVRQPD 490
Cdd:pfam05729 1 RTVILQGEAGSGKTTLLQKLALLWAQGKLPQGfDFVFFLPCRELSRSGNARSLADLLFSQWPEPAAPVSEVWAVILELPE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196069858 491 RVLLILDAFEELEAQDGLLHGPCGPLppepcsfrGLLAGLFQRKLLRGCTLLLTARPRGR--LTQSLSKADaIFEVPSFS 568
Cdd:pfam05729 81 RLLLILDGLDELVSDLGQLDGPCPVL--------TLLSSLLRKKLLPGASLLLTVRPDALrdLRRGLEEPR-YLEVRGFS 151
|
170
....*....|....*
gi 1196069858 569 TRQAQTYMRHYFENS 583
Cdd:pfam05729 152 ESDRKQYVRKYFSDE 166
|
|
| RNA1 |
COG5238 |
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ... |
971-1123 |
3.46e-17 |
|
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];
Pssm-ID: 444072 [Multi-domain] Cd Length: 434 Bit Score: 85.61 E-value: 3.46e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196069858 971 LVKILPAFSSLQHLDLdslSENKIGDEGVSRLAATFTQLKVLETLNLSQNSITDVGACKLAEALPALaKSLLRLsSLYNN 1050
Cdd:COG5238 284 LAKALQGNTTLTSLDL---SVNRIGDEGAIALAEGLQGNKTLHTLNLAYNGIGAQGAIALAKALQEN-TTLHSL-DLSDN 358
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1196069858 1051 CICDAGARSLAQVLPDMVSLRVMDVQFNKFTAAGAQQLASSLQKcPQVETLAMWTPTIPFGVQEHLQQLDSRI 1123
Cdd:COG5238 359 QIGDEGAIALAKYLEGNTTLRELNLGKNNIGKQGAEALIDALQT-NRLHTLILDGNLIGAEAQQRLEQLLERI 430
|
|
| RNA1 |
COG5238 |
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ... |
964-1101 |
1.41e-16 |
|
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];
Pssm-ID: 444072 [Multi-domain] Cd Length: 434 Bit Score: 83.69 E-value: 1.41e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196069858 964 GPQAFPTLVKILPAFSSLQHLDLdslSENKIGDEGVSRLAATFTQLKVLETLNLSQNSITDVGACKLAEALpALAKSLLR 1043
Cdd:COG5238 221 GDEGAEILAEALKGNKSLTTLDL---SNNQIGDEGVIALAEALKNNTTVETLYLSGNQIGAEGAIALAKAL-QGNTTLTS 296
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*...
gi 1196069858 1044 LSSLYNNcICDAGARSLAQVLPDMVSLRVMDVQFNKFTAAGAQQLASSLQKCPQVETL 1101
Cdd:COG5238 297 LDLSVNR-IGDEGAIALAEGLQGNKTLHTLNLAYNGIGAQGAIALAKALQENTTLHSL 353
|
|
| RNA1 |
COG5238 |
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ... |
963-1101 |
3.59e-16 |
|
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];
Pssm-ID: 444072 [Multi-domain] Cd Length: 434 Bit Score: 82.53 E-value: 3.59e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196069858 963 LGPQAFPTLVKILPAFSSLQHLDLdslSENKIGDEGVSRLAATFTQLKVLETLNLSQNSITDVGACKLAEALpALAKSLL 1042
Cdd:COG5238 248 IGDEGVIALAEALKNNTTVETLYL---SGNQIGAEGAIALAKALQGNTTLTSLDLSVNRIGDEGAIALAEGL-QGNKTLH 323
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*....
gi 1196069858 1043 RLSSLYNNcICDAGARSLAQVLPDMVSLRVMDVQFNKFTAAGAQQLASSLQKCPQVETL 1101
Cdd:COG5238 324 TLNLAYNG-IGAQGAIALAKALQENTTLHSLDLSDNQIGDEGAIALAKYLEGNTTLREL 381
|
|
| RNA1 |
COG5238 |
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ... |
982-1118 |
4.30e-15 |
|
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];
Pssm-ID: 444072 [Multi-domain] Cd Length: 434 Bit Score: 79.06 E-value: 4.30e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196069858 982 QHLDLDSLSENKIGDEGVSRLAATFTQLKVLETLNLSQNSITDVGACKLAEALPALAKslLRLSSLYNNCICDAGARSLA 1061
Cdd:COG5238 180 NSVETVYLGCNQIGDEGIEELAEALTQNTTVTTLWLKRNPIGDEGAEILAEALKGNKS--LTTLDLSNNQIGDEGVIALA 257
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1196069858 1062 QVLPDMVSLRVMDVQFNKFTAAGAQQLASSLQKCPQVETLAMWTPTIPF----GVQEHLQQ 1118
Cdd:COG5238 258 EALKNNTTVETLYLSGNQIGAEGAIALAKALQGNTTLTSLDLSVNRIGDegaiALAEGLQG 318
|
|
| RNA1 |
COG5238 |
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ... |
963-1101 |
7.45e-14 |
|
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];
Pssm-ID: 444072 [Multi-domain] Cd Length: 434 Bit Score: 75.21 E-value: 7.45e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196069858 963 LGPQAFPTLVKILPAFSSLQHLDLdslSENKIGDEGVSRLAATFTQLKVLETLNLSQNSITDVGACKLAEALpALAKSLL 1042
Cdd:COG5238 192 IGDEGIEELAEALTQNTTVTTLWL---KRNPIGDEGAEILAEALKGNKSLTTLDLSNNQIGDEGVIALAEAL-KNNTTVE 267
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*....
gi 1196069858 1043 RLsSLYNNCICDAGARSLAQVLPDMVSLRVMDVQFNKFTAAGAQQLASSLQKCPQVETL 1101
Cdd:COG5238 268 TL-YLSGNQIGAEGAIALAKALQGNTTLTSLDLSVNRIGDEGAIALAEGLQGNKTLHTL 325
|
|
| NACHT |
COG5635 |
Predicted NTPase, NACHT family domain [Signal transduction mechanisms]; |
327-1071 |
1.03e-09 |
|
Predicted NTPase, NACHT family domain [Signal transduction mechanisms];
Pssm-ID: 444362 [Multi-domain] Cd Length: 935 Bit Score: 62.90 E-value: 1.03e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196069858 327 IKLPKWPASVERFQHSLKDKYQVEPENLSVPMVAVELVRARLERGSNKSQERELATPDWTERQLARGGLDQVLQAVVDRR 406
Cdd:COG5635 88 ESLLLLLLLLLLLAEALLALLELAALLKAVLLSLSGGSDLVLLLSESDLLLALLILLLDADGLLVSLDDLYVPLNLLERI 167
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196069858 407 RPRET--------QVVAVLGKAGQGKSHWAR-TVSQAWARGQLPQYDFVFYVPCHclDHPGDtYHLQDLLCPPSLQPLVM 477
Cdd:COG5635 168 ESLKRlelleakkKRLLILGEPGSGKTTLLRyLALELAERYLDAEDPIPILIELR--DLAEE-ASLEDLLAEALEKRGGE 244
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196069858 478 DDEVLGHIVRQpDRVLLILDAFEELEAQDGLLHgpcgplppepcsFRGLLAGLFQRklLRGCTLLLTARPRGRLTQSLSK 557
Cdd:COG5635 245 PEDALERLLRN-GRLLLLLDGLDEVPDEADRDE------------VLNQLRRFLER--YPKARVIITSRPEGYDSSELEG 309
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196069858 558 ADaIFEVPSFSTRQAQTYMRHYFENsgTAGDKDKALGLLEGQPFLLTHSHSPALCRAVCQLskaLLEQGtetQLPCTLTG 637
Cdd:COG5635 310 FE-VLELAPLSDEQIEEFLKKWFEA--TERKAERLLEALEENPELRELARNPLLLTLLALL---LRERG---ELPDTRAE 380
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196069858 638 LYVGLL------GPAVRDSPPG----------ALTELAKLAWELGRRHQSTLQGTQLLSEEVRTWAVTQGLVHPTMGTT- 700
Cdd:COG5635 381 LYEQFVelllerWDEQRGLTIYrelsreelreLLSELALAMQENGRTEFAREELEEILREYLGRRKDAEALLDELLLRTg 460
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196069858 701 ------ETQLAFSSFLLQCFLGAVWLAqcneirdkELPQYLALTPRKKRPYDNWLEGVPRFLTGLVFQPRAHC--LGALM 772
Cdd:COG5635 461 llvergEGRYSFAHRSFQEYLAARALV--------EELDEELLELLAEHLEDPRWREVLLLLAGLLDDVKQIKelIDALL 532
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196069858 773 EPAVADRKRKVLTRYLKRLKLGSLRAGRLLELLHCAHETQEPGIWEHVVHQLPGHLSFLGTRLTPPDVHVLGRALETASQ 852
Cdd:COG5635 533 ARDDAAALALAAALLLALLLALALLALLALLLLLRLLLALLALLLLALLLLLLLALLLALLALDLGLAALLLLLLLLLLL 612
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196069858 853 DFSLDLRQTGIEPSGLGNLVGLSCVTSFRAALSDTMVLWESLRHQGEPQLLQAAEEKFTLEPFKAKSPKDVEDLDSLVQt 932
Cdd:COG5635 613 LLLLALALLLALLLLLLLLLLAELLLLALLALVLLSLLLASRLLLITLLLLAAASAALLLLLLLLLAELLLALLALASL- 691
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196069858 933 qrlrnpSEDAALDLPAIRDLKKLEFALGPVLGPQAFPTLVKILPAFSSLQHLDLDSLSENKIGDEGVSRLAATFTQLKVL 1012
Cdd:COG5635 692 ------LLLLLLALALALALLLLAVLLAAALDLLLLLVLLLALLLVLALALSLLLLALALLLAGALLLESSALLAVLLAS 765
|
730 740 750 760 770
....*....|....*....|....*....|....*....|....*....|....*....
gi 1196069858 1013 ETLNLSQNSITDVGACKLAEALPALAKSLLRLSSLYNNCICDAGARSLAQVLPDMVSLR 1071
Cdd:COG5635 766 LLLALLLLSLLLLLVLLLALALLASLLLALLLLILLLVLLGSLLLLRLLDDLALLLLLA 824
|
|
| NLRC4_HD2 |
pfam17776 |
NLRC4 helical domain HD2; This entry represents a helical domain found in the NLRC4 protein ... |
711-813 |
1.00e-07 |
|
NLRC4 helical domain HD2; This entry represents a helical domain found in the NLRC4 protein and NOD2 protein.
Pssm-ID: 465499 [Multi-domain] Cd Length: 122 Bit Score: 51.52 E-value: 1.00e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196069858 711 LQCFLGAVWLAQCNEIRDKELPQYLaLTPRKKRPYDNWLEGVP-----------RFLTGLVFQPRAHCLGALMEPAVADR 779
Cdd:pfam17776 4 FQEFFAALFYVLSFKEEKSNPLKEF-FGLRKRESLKSLLDKALksknghldlflRFLFGLLNEENQRLLEGLLGCKLSSE 82
|
90 100 110
....*....|....*....|....*....|....
gi 1196069858 780 KRKVLTRYLKRLKLGSLRAGRLLELLHCAHETQE 813
Cdd:pfam17776 83 IKQELLQWIKSLIQKELSSERFLNLFHCLYELQD 116
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
975-1101 |
5.98e-07 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 53.40 E-value: 5.98e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196069858 975 LPAFSSLQHLDLdslSENKIGDegvsrLAATFTQLKVLETLNLSQNSITDvgackLAEALPALaKSLLRLsSLYNNCIcd 1054
Cdd:COG4886 109 LSNLTNLESLDL---SGNQLTD-----LPEELANLTNLKELDLSNNQLTD-----LPEPLGNL-TNLKSL-DLSNNQL-- 171
|
90 100 110 120
....*....|....*....|....*....|....*....|....*..
gi 1196069858 1055 agaRSLAQVLPDMVSLRVMDVQFNKFTAagaqqLASSLQKCPQVETL 1101
Cdd:COG4886 172 ---TDLPEELGNLTNLKELDLSNNQITD-----LPEPLGNLTNLEEL 210
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
847-1081 |
1.15e-05 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 49.16 E-value: 1.15e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196069858 847 LETASQDFSLDLRQTGIEPSGLGNLVGLSCVTSFRAALSDTMVLWESLRHQGEPQLLQAAEEKFTLEPFKAKSPKDVEDL 926
Cdd:COG4886 30 LLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELDLSGNEEL 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196069858 927 DSLVQTQRL---RNPSEDAALDLPAIRDLKKLEFA------LGPVLGpqAFPTLVKI---------LPA-FSSLQHLDLD 987
Cdd:COG4886 110 SNLTNLESLdlsGNQLTDLPEELANLTNLKELDLSnnqltdLPEPLG--NLTNLKSLdlsnnqltdLPEeLGNLTNLKEL 187
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196069858 988 SLSENKIGDegvsrLAATFTQLKVLETLNLSQNSITDvgackLAEALPALaKSLLRLsSLYNNCIcdagaRSLAQvLPDM 1067
Cdd:COG4886 188 DLSNNQITD-----LPEPLGNLTNLEELDLSGNQLTD-----LPEPLANL-TNLETL-DLSNNQL-----TDLPE-LGNL 249
|
250
....*....|....
gi 1196069858 1068 VSLRVMDVQFNKFT 1081
Cdd:COG4886 250 TNLEELDLSNNQLT 263
|
|
| PHA03377 |
PHA03377 |
EBNA-3C; Provisional |
120-348 |
1.63e-05 |
|
EBNA-3C; Provisional
Pssm-ID: 177614 [Multi-domain] Cd Length: 1000 Bit Score: 49.28 E-value: 1.63e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196069858 120 IERIETEEGFSESME---VPVEAGERSQKRRS----PEEHPMDPKHRKLAEPSMVPMLTGSFLMGPASISTMPYLPPALS 192
Cdd:PHA03377 517 VETTEEEESVTQPAKphrKVQDGFQRSGRRQKratpPKVSPSDRGPPKASPPVMAPPSTGPRVMATPSTGPRDMAPPSTG 596
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196069858 193 NQEPVSCHIHLEGATQTSVPPSRSSPNCLDLTIGHI----QLLPT----LPQGLWQIQgAGTGLPSVliyhgEMPQVNHV 264
Cdd:PHA03377 597 PRQQAKCKDGPPASGPHEKQPPSSAPRDMAPSVVRMflreRLLEQstgpKPKSFWEMR-AGRDGSGI-----QQEPSSRR 670
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196069858 265 IPSGSPTvsslpksPDRPCstspFAPSVADLPSMPepaltsrvneaedTTSPSPCQEGPESPIKlPKWPASverfqHSLK 344
Cdd:PHA03377 671 QPATQST-------PPRPS----WLPSVFVLPSVD-------------AGRAQPSEESHLSSMS-PTQPIS-----HEEQ 720
|
....
gi 1196069858 345 DKYQ 348
Cdd:PHA03377 721 PRYE 724
|
|
| Atrophin-1 |
pfam03154 |
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ... |
143-429 |
6.99e-05 |
|
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.
Pssm-ID: 460830 [Multi-domain] Cd Length: 991 Bit Score: 47.07 E-value: 6.99e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196069858 143 SQKRRSPEEHPMDPK-----HRKLAEPSMVPMLTG-------SFLMGPASISTMPYLPP--------ALSNQEPVSCHih 202
Cdd:pfam03154 334 LQSQQPPREQPLPPAplsmpHIKPPPTTPIPQLPNpqshkhpPHLSGPSPFQMNSNLPPppalkplsSLSTHHPPSAH-- 411
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196069858 203 legatqtsVPPSRSSPNCLDLtighiQLLPTLPQGLWQIQG---AGTGLPSVLIYHGEMPQ----VNHVIPSGSPTVSSl 275
Cdd:pfam03154 412 --------PPPLQLMPQSQQL-----PPPPAQPPVLTQSQSlppPAASHPPTSGLHQVPSQspfpQHPFVPGGPPPITP- 477
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196069858 276 PKSPdrPCSTSPFAP------SVADLPSMPEPALTSRV-----------NEAEDTTSPSPCQEGPESP---IKLPKWPAS 335
Cdd:pfam03154 478 PSGP--PTSTSSAMPgiqppsSASVSSSGPVPAAVSCPlppvqikeealDEAEEPESPPPPPRSPSPEptvVNTPSHASQ 555
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196069858 336 VERFQHSLKDKYQ--VEPENLSVPMVAVELVRARLERGSNKSQERELATPDWTERQLARGGldqvlqavvDRRRPRETQV 413
Cdd:pfam03154 556 SARFYKHLDRGYNscARTDLYFMPLAGSKLAKKREEALEKAKREAEQKAREEKEREKEKEK---------ERERERERER 626
|
330
....*....|....*.
gi 1196069858 414 VAVLGKAGQGKSHWAR 429
Cdd:pfam03154 627 EAERAAKASSSSHEGR 642
|
|
| LRR_RI |
smart00368 |
Leucine rich repeat, ribonuclease inhibitor type; |
1039-1066 |
1.42e-03 |
|
Leucine rich repeat, ribonuclease inhibitor type;
Pssm-ID: 197686 [Multi-domain] Cd Length: 28 Bit Score: 37.00 E-value: 1.42e-03
10 20
....*....|....*....|....*...
gi 1196069858 1039 KSLLRLSsLYNNCICDAGARSLAQVLPD 1066
Cdd:smart00368 2 PSLRELD-LSNNKLGDEGARALAEALKD 28
|
|
| PRK15387 |
PRK15387 |
type III secretion system effector E3 ubiquitin transferase SspH2; |
164-317 |
7.51e-03 |
|
type III secretion system effector E3 ubiquitin transferase SspH2;
Pssm-ID: 185285 [Multi-domain] Cd Length: 788 Bit Score: 40.53 E-value: 7.51e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1196069858 164 PSMVPMLTGSFLMGPASISTMPYLPPALSNQEpvschihLEGATQTSVPPsrSSPNCLDLTI--GHIQLLPTLPQGLWQI 241
Cdd:PRK15387 217 PDCLPAHITTLVIPDNNLTSLPALPPELRTLE-------VSGNQLTSLPV--LPPGLLELSIfsNPLTHLPALPSGLCKL 287
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1196069858 242 QGAGTGLPSVLIyhgeMPQVNHVIPSGSPTVSSLPKSPDRPCSTSPFAPSVADLPSMPEPALTSRVNEAEDTTSPS 317
Cdd:PRK15387 288 WIFGNQLTSLPV----LPPGLQELSVSDNQLASLPALPSELCKLWAYNNQLTSLPTLPSGLQELSVSDNQLASLPT 359
|
|
| |
