NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1239891331|ref|XP_022264442|]
View 

protocadherin gamma-C3 isoform X24 [Canis lupus familiaris]

Protein Classification

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
Cadherin_tail super family cl24520
Cadherin C-terminal cytoplasmic tail, catenin-binding region; Cadherin_tail is the cytoplasmic ...
 13-107 1.99e-26

Cadherin C-terminal cytoplasmic tail, catenin-binding region; Cadherin_tail is the cytoplasmic domain at the C-terminus of cadherin proteins. This domain binds p120 catenin, an action critical for the surface stability of cadherin-catenin cell-cell adhesion complexes.


The actual alignment was detected with superfamily member pfam15974:

Pssm-ID: 435046  Cd Length: 134  Bit Score: 95.86  E-value: 1.99e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239891331  13 PPNTDWRFSQAQRPGTSGS-QNGDETGTWPNNQFDTEMLQAMILASA--SEAADGSSTLGGGAGTMGLSARYGPQFTLQH 89
Cdd:pfam15974   2 PPNPDWRYSASLRAGPMQSsVHMEEAGVLRGGPGGLEQQWPTVSSATpePEAGEVSPPVGAGVNSNSWTFRYGPGNPKQP 81

                          90
                  ....*....|....*....
gi 1239891331  90 VPD-YRQNVYIPGSNATLT 107
Cdd:pfam15974  82 VPGeYPENFIIPGSPAIIS 100
 
Name Accession Description Interval E-value
Cadherin_tail pfam15974
Cadherin C-terminal cytoplasmic tail, catenin-binding region; Cadherin_tail is the cytoplasmic ...
 13-107 1.99e-26

Cadherin C-terminal cytoplasmic tail, catenin-binding region; Cadherin_tail is the cytoplasmic domain at the C-terminus of cadherin proteins. This domain binds p120 catenin, an action critical for the surface stability of cadherin-catenin cell-cell adhesion complexes.


Pssm-ID: 435046  Cd Length: 134  Bit Score: 95.86  E-value: 1.99e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239891331  13 PPNTDWRFSQAQRPGTSGS-QNGDETGTWPNNQFDTEMLQAMILASA--SEAADGSSTLGGGAGTMGLSARYGPQFTLQH 89
Cdd:pfam15974   2 PPNPDWRYSASLRAGPMQSsVHMEEAGVLRGGPGGLEQQWPTVSSATpePEAGEVSPPVGAGVNSNSWTFRYGPGNPKQP 81

                          90
                  ....*....|....*....
gi 1239891331  90 VPD-YRQNVYIPGSNATLT 107
Cdd:pfam15974  82 VPGeYPENFIIPGSPAIIS 100
 
Name Accession Description Interval E-value
Cadherin_tail pfam15974
Cadherin C-terminal cytoplasmic tail, catenin-binding region; Cadherin_tail is the cytoplasmic ...
 13-107 1.99e-26

Cadherin C-terminal cytoplasmic tail, catenin-binding region; Cadherin_tail is the cytoplasmic domain at the C-terminus of cadherin proteins. This domain binds p120 catenin, an action critical for the surface stability of cadherin-catenin cell-cell adhesion complexes.


Pssm-ID: 435046  Cd Length: 134  Bit Score: 95.86  E-value: 1.99e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1239891331  13 PPNTDWRFSQAQRPGTSGS-QNGDETGTWPNNQFDTEMLQAMILASA--SEAADGSSTLGGGAGTMGLSARYGPQFTLQH 89
Cdd:pfam15974   2 PPNPDWRYSASLRAGPMQSsVHMEEAGVLRGGPGGLEQQWPTVSSATpePEAGEVSPPVGAGVNSNSWTFRYGPGNPKQP 81

                          90
                  ....*....|....*....
gi 1239891331  90 VPD-YRQNVYIPGSNATLT 107
Cdd:pfam15974  82 VPGeYPENFIIPGSPAIIS 100
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH