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Conserved domains on  [gi|1370459521|ref|XP_024304323|]
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nuclear mitotic apparatus protein 1 isoform X1 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
HkD_NuMA cd22224
Hook domain found in nuclear mitotic apparatus protein (NuMA) and similar proteins; NuMA, also ...
 6-152 4.65e-58

Hook domain found in nuclear mitotic apparatus protein (NuMA) and similar proteins; NuMA, also called nuclear mitotic apparatus protein 1, or nuclear matrix protein-22 (NMP-22), or SP-H antigen, is a microtubule (MT)-binding protein that plays a role in the formation and maintenance of the spindle poles, and the alignment and segregation of chromosomes during mitotic cell division. The model corresponds to the N-terminal conserved globular Hook domain of NuMA, which folds as a variant of the helical calponin homology (CH) domain. It directly binds dynein light intermediate chains LIC1 and LIC2 through a conserved hydrophobic patch shared among other Hook adaptors.


:

Pssm-ID: 411795  Cd Length: 148  Bit Score: 197.41  E-value: 4.65e-58
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521    6 TRGAALLSWVNSLHVADPVEAVLQLQDCSIFIKIIDRIHGTEEGQQILKQPVSERLDFVCSFLQKNRKHPSSPECLVSAQ 85
Cdd:cd22224      2 TKAEALLSWVNSLKLDDPIESISQLQDGTILLKIIYKLKGEEEEEQILDLSVEERLEFISSFLEGDCRFNSSQGTLVSWQ 81

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1370459521   86 KVLEG--SELELAKMTMLLLYHSTMSSKSPrdWEQFEYKIQAELAVILKFVLDHEDGLNLNEDLENFLQ 152
Cdd:cd22224     82 KILQGenLELELAKVLLLLLYHSMMNNNLT--LEKLDYKTELELASILRFVLDNEDGLYLSEGLDKFLT 148
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 215-911 5.39e-27

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 120.93  E-value: 5.39e-27
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  215 QMRRLKKQLADERSNRDELELELAENRKLLTEKDAQIAMMQQRIDRL--ALLNEKQAASPLE------PKELEELRDKNE 286
Cdd:TIGR02168  240 ELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELqkELYALANEISRLEqqkqilRERLANLERQLE 319

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  287 SLTMRLHETLKQCQDLKTEKSQMDRKINQLSEENGDLSFKLREFASHLQQLQDALNELTEEH---SKATQEWLEKQAQLE 363
Cdd:TIGR02168  320 ELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLetlRSKVAQLELQIASLN 399

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  364 KELSAALQDKKCLEEKNEILQgklSQLEEHLSQLQDNPPQEKGEvlgdvlQLETLKQEAATLAANNTQLQARVEMLETER 443
Cdd:TIGR02168  400 NEIERLEARLERLEDRRERLQ---QEIEELLKKLEEAELKELQA------ELEELEEELEELQEELERLEEALEELREEL 470

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  444 GQQEAKLLAERGHFEEEKQQLSSLITDLQSSISNLSQAKEELEQASQAHGAR-LTAQVASLTSEL-----TTLNATIQ-- 515
Cdd:TIGR02168  471 EEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILgVLSELISVDEGYeaaieAALGGRLQav 550

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  516 ------QQDQELAGLKQQAKEK-------QAQLAQTLQQQEQASQGLRHQVEQLSSSLKQKEQ----------QLKEVAE 572
Cdd:TIGR02168  551 vvenlnAAKKAIAFLKQNELGRvtflpldSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKlrkalsyllgGVLVVDD 630

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  573 KQEATRQ----DHAQQLAT--------------AAEEREASLRERDAALKQLEALEKEKAAKLEILQQQLQVANEARDSA 634
Cdd:TIGR02168  631 LDNALELakklRPGYRIVTldgdlvrpggvitgGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEEL 710

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  635 QTSVTQAQREKAELSRKVEELQACVETARQEQHEAQAQVAELELQLRSEQQKAT------------------EKERVAQE 696
Cdd:TIGR02168  711 EEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEeleerleeaeeelaeaeaEIEELEAQ 790

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  697 KDQLQEQLQALKESLKVTKGSLEEEKRRAADALEEQQRCISELKAETRSLVEQHKRERKELEEERAGRKGLEaRLQQLGE 776
Cdd:TIGR02168  791 IEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIE-ELEELIE 869

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  777 AHQAETEVLRRELAEAMAAQHTAESECEQLVKEVAAWRERyedsqqeeaqygamfqeqLMTLKEECEKARQELQEAKEKV 856
Cdd:TIGR02168  870 ELESELEALLNERASLEEALALLRSELEELSEELRELESK------------------RSELRRELEELREKLAQLELRL 931

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1370459521  857 AGIeshsELQISRQQNELAELHA-NLARALQQVQEKEVRAQKLADDLSTLQEKMAA 911
Cdd:TIGR02168  932 EGL----EVRIDNLQERLSEEYSlTLEEAEALENKIEDDEEEARRRLKRLENKIKE 983
NuMA_LGNBD cd22298
LGN binding domain (LGNBD) of nuclear mitotic apparatus protein (NuMA) and similar proteins; ...
 1888-1946 1.13e-26

LGN binding domain (LGNBD) of nuclear mitotic apparatus protein (NuMA) and similar proteins; NuMA, also called nuclear matrix protein-22 (NMP-22), nuclear mitotic apparatus protein 1 (NUMA1), or SP-H antigen, is a microtubule (MT)-binding protein that plays a role in the formation and maintenance of spindle poles and the alignment and segregation of chromosomes during mitotic cell division. It is involved in the establishment of mitotic spindle orientation during metaphase, and elongation during anaphase in a dynein-dynactin-dependent manner. NuMA, in complex with LGN, forms NuMA:LGN hetero-hexamers that promote spindle orientation. The model corresponds to the LGN binding domain (LGNBD) of NuMA. LGN (named for leu-gly-asn repeats) is also known as G protein signaling modulator 2.


:

Pssm-ID: 412093  Cd Length: 56  Bit Score: 104.22  E-value: 1.13e-26
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1370459521 1888 LLSLPGYRPTTRSSARRSQagvSSGAPPGRNSFYMGTCQDEPEQLDDWNRIAELQQRNR 1946
Cdd:cd22298      1 LLSLPGYRPSTRSSTRRSQ---SSSATGGRSTFYMGTCQDEPEHLDDWNRIAELQQRNR 56
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1023-1656 1.64e-22

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 105.79  E-value: 1.64e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1023 EKAARA-ELEMRLQNALNEQRV-EFATLQEALAHALTEKEGKDQELAKLRGLEAAQIKELEELRQTVKQLKEQL-AKKEK 1099
Cdd:COG1196    210 EKAERYrELKEELKELEAELLLlKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELeEAQAE 289

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1100 EHASGSgaqseaagrteptgpKLEALRAEVSKLEQQCQKQQEQADSLERSLEAERASRAERDSALETLQGQLEEKAQELG 1179
Cdd:COG1196    290 EYELLA---------------ELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELE 354

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1180 HSQSALASAQRELAAFRTKVQDHSKAEDEWKAQVARGRQEAERKNSLISSLEEEVSILNRQVLEKEGESKELKrlvmAES 1259
Cdd:COG1196    355 EAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELE----EAL 430

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1260 EKSQKLEERLRLLQAETASNSARAAERSSALREEVQSLREEAEKQRVASENLRQELTSQAERAEELGQELKawqekffqk 1339
Cdd:COG1196    431 AELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEA--------- 501

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1340 eqalstlQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKRHREELEQSkqAAGGLRAELLRAQRELGELIPLRQKVAEQ 1419
Cdd:COG1196    502 -------DYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAA--LAAALQNIVVEDDEVAAAAIEYLKAAKAG 572

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1420 ERTAQQLRAEKASYAEQlsmlkkahgllAEENRGLGERANLGRQFLEVELDqAREKYVQELAAVRADAETRLAEVQREAQ 1499
Cdd:COG1196    573 RATFLPLDKIRARAALA-----------AALARGAIGAAVDLVASDLREAD-ARYYVLGDTLLGRTLVAARLEAALRRAV 640

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1500 STARELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVEQLEvfqrEQTKQVEELSKKLADSDQASKVQQQKLKAVQAQG 1579
Cdd:COG1196    641 TLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELE----ELAERLAEEELELEEALLAEEEEERELAEAEEER 716

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1370459521 1580 GESQQEAQRLQAQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAkkqqnqelqeqlrSLEQLQKENKELRAEAERLG 1656
Cdd:COG1196    717 LEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPP-------------DLEELERELERLEREIEALG 780
EnvC super family cl34844
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 832-1042 2.24e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG4942:

Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 52.07  E-value: 2.24e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  832 QEQLMTLKEECEKARQELQEAKEKVAGIEShselQISRQQNELAELHANLARALQQVQEKEVRAQKLADDLSTLQEKMAA 911
Cdd:COG4942     26 EAELEQLQQEIAELEKELAALKKEEKALLK----QLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEA 101

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  912 TSKEVARLETLVRKAGEQQETASRELVKEPARAGDRQpEWLE------EQQGRQFCSTQAALQAMEREAEQMGNELERLR 985
Cdd:COG4942    102 QKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRL-QYLKylaparREQAEELRADLAELAALRAELEAERAELEALL 180

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1370459521  986 AALMESQGQQQEERGQQEREVARLTQERGRAQADLALEKAARAELEMRLQNALNEQR 1042
Cdd:COG4942    181 AELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAA 237
PHA03307 super family cl33723
transcriptional regulator ICP4; Provisional
 1764-2034 3.68e-04

transcriptional regulator ICP4; Provisional


The actual alignment was detected with superfamily member PHA03307:

Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 45.93  E-value: 3.68e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1764 PDGTSVPGEPASPISQRlPPKVESLESLYFTPIPARSQA--PLESSLDSLGDVFLDSGRKTRSARRRTTQIINITMTKKL 1841
Cdd:PHA03307   192 EPPPSTPPAAASPRPPR-RSSPISASASSPAPAPGRSAAddAGASSSDSSSSESSGCGWGPENECPLPRPAPITLPTRIW 270

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1842 DVEEPDsaNSSFYSTRSAPASQASLRATSSTQSLARLGSPDYGNSALLSLPGYRP-----TTRSSARRSQAGVSSGAPPG 1916
Cdd:PHA03307   271 EASGWN--GPSSRPGPASSSSSPRERSPSPSPSSPGSGPAPSSPRASSSSSSSREsssssTSSSSESSRGAAVSPGPSPS 348

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1917 RNsfymGTCQDEPeqldDWNRIAELQQRnrvCPPHLKTCYPLESRPSlslgtitdeemktgdpqETLRRASMQ---PIQI 1993
Cdd:PHA03307   349 RS----PSPSRPP----PPADPSSPRKR---PRPSRAPSSPAASAGR-----------------PTRRRARAAvagRARR 400

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|.
gi 1370459521 1994 AEGTGITTRQQRKRVSLEPHQGPGTPESKkatscfPRPMTP 2034
Cdd:PHA03307   401 RDATGRFPAGRPRPSPLDAGAASGAFYAR------YPLLTP 435
 
Name Accession Description Interval E-value
HkD_NuMA cd22224
Hook domain found in nuclear mitotic apparatus protein (NuMA) and similar proteins; NuMA, also ...
 6-152 4.65e-58

Hook domain found in nuclear mitotic apparatus protein (NuMA) and similar proteins; NuMA, also called nuclear mitotic apparatus protein 1, or nuclear matrix protein-22 (NMP-22), or SP-H antigen, is a microtubule (MT)-binding protein that plays a role in the formation and maintenance of the spindle poles, and the alignment and segregation of chromosomes during mitotic cell division. The model corresponds to the N-terminal conserved globular Hook domain of NuMA, which folds as a variant of the helical calponin homology (CH) domain. It directly binds dynein light intermediate chains LIC1 and LIC2 through a conserved hydrophobic patch shared among other Hook adaptors.


Pssm-ID: 411795  Cd Length: 148  Bit Score: 197.41  E-value: 4.65e-58
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521    6 TRGAALLSWVNSLHVADPVEAVLQLQDCSIFIKIIDRIHGTEEGQQILKQPVSERLDFVCSFLQKNRKHPSSPECLVSAQ 85
Cdd:cd22224      2 TKAEALLSWVNSLKLDDPIESISQLQDGTILLKIIYKLKGEEEEEQILDLSVEERLEFISSFLEGDCRFNSSQGTLVSWQ 81

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1370459521   86 KVLEG--SELELAKMTMLLLYHSTMSSKSPrdWEQFEYKIQAELAVILKFVLDHEDGLNLNEDLENFLQ 152
Cdd:cd22224     82 KILQGenLELELAKVLLLLLYHSMMNNNLT--LEKLDYKTELELASILRFVLDNEDGLYLSEGLDKFLT 148
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 215-911 5.39e-27

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 120.93  E-value: 5.39e-27
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  215 QMRRLKKQLADERSNRDELELELAENRKLLTEKDAQIAMMQQRIDRL--ALLNEKQAASPLE------PKELEELRDKNE 286
Cdd:TIGR02168  240 ELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELqkELYALANEISRLEqqkqilRERLANLERQLE 319

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  287 SLTMRLHETLKQCQDLKTEKSQMDRKINQLSEENGDLSFKLREFASHLQQLQDALNELTEEH---SKATQEWLEKQAQLE 363
Cdd:TIGR02168  320 ELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLetlRSKVAQLELQIASLN 399

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  364 KELSAALQDKKCLEEKNEILQgklSQLEEHLSQLQDNPPQEKGEvlgdvlQLETLKQEAATLAANNTQLQARVEMLETER 443
Cdd:TIGR02168  400 NEIERLEARLERLEDRRERLQ---QEIEELLKKLEEAELKELQA------ELEELEEELEELQEELERLEEALEELREEL 470

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  444 GQQEAKLLAERGHFEEEKQQLSSLITDLQSSISNLSQAKEELEQASQAHGAR-LTAQVASLTSEL-----TTLNATIQ-- 515
Cdd:TIGR02168  471 EEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILgVLSELISVDEGYeaaieAALGGRLQav 550

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  516 ------QQDQELAGLKQQAKEK-------QAQLAQTLQQQEQASQGLRHQVEQLSSSLKQKEQ----------QLKEVAE 572
Cdd:TIGR02168  551 vvenlnAAKKAIAFLKQNELGRvtflpldSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKlrkalsyllgGVLVVDD 630

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  573 KQEATRQ----DHAQQLAT--------------AAEEREASLRERDAALKQLEALEKEKAAKLEILQQQLQVANEARDSA 634
Cdd:TIGR02168  631 LDNALELakklRPGYRIVTldgdlvrpggvitgGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEEL 710

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  635 QTSVTQAQREKAELSRKVEELQACVETARQEQHEAQAQVAELELQLRSEQQKAT------------------EKERVAQE 696
Cdd:TIGR02168  711 EEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEeleerleeaeeelaeaeaEIEELEAQ 790

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  697 KDQLQEQLQALKESLKVTKGSLEEEKRRAADALEEQQRCISELKAETRSLVEQHKRERKELEEERAGRKGLEaRLQQLGE 776
Cdd:TIGR02168  791 IEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIE-ELEELIE 869

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  777 AHQAETEVLRRELAEAMAAQHTAESECEQLVKEVAAWRERyedsqqeeaqygamfqeqLMTLKEECEKARQELQEAKEKV 856
Cdd:TIGR02168  870 ELESELEALLNERASLEEALALLRSELEELSEELRELESK------------------RSELRRELEELREKLAQLELRL 931

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1370459521  857 AGIeshsELQISRQQNELAELHA-NLARALQQVQEKEVRAQKLADDLSTLQEKMAA 911
Cdd:TIGR02168  932 EGL----EVRIDNLQERLSEEYSlTLEEAEALENKIEDDEEEARRRLKRLENKIKE 983
NuMA_LGNBD cd22298
LGN binding domain (LGNBD) of nuclear mitotic apparatus protein (NuMA) and similar proteins; ...
 1888-1946 1.13e-26

LGN binding domain (LGNBD) of nuclear mitotic apparatus protein (NuMA) and similar proteins; NuMA, also called nuclear matrix protein-22 (NMP-22), nuclear mitotic apparatus protein 1 (NUMA1), or SP-H antigen, is a microtubule (MT)-binding protein that plays a role in the formation and maintenance of spindle poles and the alignment and segregation of chromosomes during mitotic cell division. It is involved in the establishment of mitotic spindle orientation during metaphase, and elongation during anaphase in a dynein-dynactin-dependent manner. NuMA, in complex with LGN, forms NuMA:LGN hetero-hexamers that promote spindle orientation. The model corresponds to the LGN binding domain (LGNBD) of NuMA. LGN (named for leu-gly-asn repeats) is also known as G protein signaling modulator 2.


Pssm-ID: 412093  Cd Length: 56  Bit Score: 104.22  E-value: 1.13e-26
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1370459521 1888 LLSLPGYRPTTRSSARRSQagvSSGAPPGRNSFYMGTCQDEPEQLDDWNRIAELQQRNR 1946
Cdd:cd22298      1 LLSLPGYRPSTRSSTRRSQ---SSSATGGRSTFYMGTCQDEPEHLDDWNRIAELQQRNR 56
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 470-1095 3.01e-25

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 114.65  E-value: 3.01e-25
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  470 DLQSSISNLSQAKEELEQASQAHgARLTAQVASLTSELTTLNATIQQQDQELAGLKQQAKEKQAQLAQTLQQQEQASQGL 549
Cdd:COG1196    226 EAELLLLKLRELEAELEELEAEL-EELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDI 304

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  550 RHQVEQLsSSLKQKEQQLKEVAEKQEATRQDHAQQLATAAEEREASLRERDAALKQLEALEKEKAAKLEILQQQLQVANE 629
Cdd:COG1196    305 ARLEERR-RELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEE 383

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  630 ARDSAQtsvtQAQREKAELSRKVEELQACVETARQEQHEAQAQVAELELQLRSEQQKATEKERVAQEKDQLQEQLQALKE 709
Cdd:COG1196    384 LAEELL----EALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEE 459

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  710 SLKVTKGSLEEEKRRAADALEEQQRCISELKAEtrslveqhkrerkeleeeragrkgLEARLQQLGEAHQAETEVLRREL 789
Cdd:COG1196    460 ALLELLAELLEEAALLEAALAELLEELAEAAAR------------------------LLLLLEAEADYEGFLEGVKAALL 515

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  790 AEAMAAQHtaeseceQLVKEVAAWRERYEDSQQEEAqyGAMFQEQLMTLKEECEKARQELQEAKEKVAGIESHSELQISR 869
Cdd:COG1196    516 LAGLRGLA-------GAVAVLIGVEAAYEAALEAAL--AAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARA 586

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  870 QQNELAELHANLARALQQVQEKEVRAQKLADDLSTLQEKMAATSKEVARLETLVRKAGEQQETASRELVKEPARAgdrqp 949
Cdd:COG1196    587 ALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGS----- 661

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  950 ewleeqqgrqfcSTQAALQAMEREAEQMGNELERLRAALMESQGQQQEERGQQEREVARLTQERGRAQADLALEKAARAE 1029
Cdd:COG1196    662 ------------LTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQ 729

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1370459521 1030 LEMRLQNALNEQRVEFATLQEALAHALTEKEGKDQELAKLRGLEA----------AQIKELEELRQTVKQLKEQLA 1095
Cdd:COG1196    730 LEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEReiealgpvnlLAIEEYEELEERYDFLSEQRE 805
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1023-1656 1.64e-22

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 105.79  E-value: 1.64e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1023 EKAARA-ELEMRLQNALNEQRV-EFATLQEALAHALTEKEGKDQELAKLRGLEAAQIKELEELRQTVKQLKEQL-AKKEK 1099
Cdd:COG1196    210 EKAERYrELKEELKELEAELLLlKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELeEAQAE 289

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1100 EHASGSgaqseaagrteptgpKLEALRAEVSKLEQQCQKQQEQADSLERSLEAERASRAERDSALETLQGQLEEKAQELG 1179
Cdd:COG1196    290 EYELLA---------------ELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELE 354

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1180 HSQSALASAQRELAAFRTKVQDHSKAEDEWKAQVARGRQEAERKNSLISSLEEEVSILNRQVLEKEGESKELKrlvmAES 1259
Cdd:COG1196    355 EAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELE----EAL 430

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1260 EKSQKLEERLRLLQAETASNSARAAERSSALREEVQSLREEAEKQRVASENLRQELTSQAERAEELGQELKawqekffqk 1339
Cdd:COG1196    431 AELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEA--------- 501

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1340 eqalstlQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKRHREELEQSkqAAGGLRAELLRAQRELGELIPLRQKVAEQ 1419
Cdd:COG1196    502 -------DYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAA--LAAALQNIVVEDDEVAAAAIEYLKAAKAG 572

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1420 ERTAQQLRAEKASYAEQlsmlkkahgllAEENRGLGERANLGRQFLEVELDqAREKYVQELAAVRADAETRLAEVQREAQ 1499
Cdd:COG1196    573 RATFLPLDKIRARAALA-----------AALARGAIGAAVDLVASDLREAD-ARYYVLGDTLLGRTLVAARLEAALRRAV 640

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1500 STARELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVEQLEvfqrEQTKQVEELSKKLADSDQASKVQQQKLKAVQAQG 1579
Cdd:COG1196    641 TLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELE----ELAERLAEEELELEEALLAEEEEERELAEAEEER 716

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1370459521 1580 GESQQEAQRLQAQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAkkqqnqelqeqlrSLEQLQKENKELRAEAERLG 1656
Cdd:COG1196    717 LEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPP-------------DLEELERELERLEREIEALG 780
PTZ00121 PTZ00121
MAEBL; Provisional
 595-1328 1.80e-20

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 99.83  E-value: 1.80e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  595 SLRERDAALKQLEALEKEKAAKLEILQQQLQVANEARDSAQTSVTQAQR-----EKAELSRKVEELQACVETARQEQHEA 669
Cdd:PTZ00121  1068 QDEGLKPSYKDFDFDAKEDNRADEATEEAFGKAEEAKKTETGKAEEARKaeeakKKAEDARKAEEARKAEDARKAEEARK 1147

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  670 QAQVAELELQLRSEQQKATEKERVAQEKDQLQEQLQALkESLKVTKGSLEEEKRRAadalEEQQRCISELKAETRSLVEQ 749
Cdd:PTZ00121  1148 AEDAKRVEIARKAEDARKAEEARKAEDAKKAEAARKAE-EVRKAEELRKAEDARKA----EAARKAEEERKAEEARKAED 1222

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  750 HKRERKELEEERAGRKGLEARLQQLGEAHQAETEVLRRELAEAMAAQHTAESECEQLVKEVaawRERYEDSQQEEAQYGa 829
Cdd:PTZ00121  1223 AKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADEL---KKAEEKKKADEAKKA- 1298

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  830 mfqeqlmtlkEECEKARQELQEAKEKVAGIESHSELQISRQQNELAELHANLARALQQVQEKEvrAQKLADDLSTLQEKM 909
Cdd:PTZ00121  1299 ----------EEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAE--AEAAADEAEAAEEKA 1366

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  910 AA----TSKEVARLETLVRKAGEQQETasrELVKEPARAGDRQPEWLEEQQGRQFCSTQAALQAME-REAEQMGNELERL 984
Cdd:PTZ00121  1367 EAaekkKEEAKKKADAAKKKAEEKKKA---DEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEkKKADEAKKKAEEA 1443

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  985 RAAlmesqgqqqeergqqerevarlTQERGRAQADLALEKAARAELEMRLQNALNEQRVEFATLQEALAHAlTEKEGKDQ 1064
Cdd:PTZ00121  1444 KKA----------------------DEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKA-EEAKKKAD 1500

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1065 ELAKlrglEAAQIKELEELRQTVKQLKEQLAKKEKEHASGSGAQSEAAGRTEPTGPKLEALRA--EVSKLEQQCQKQQEQ 1142
Cdd:PTZ00121  1501 EAKK----AAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKaeEKKKAEEAKKAEEDK 1576

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1143 ADSLERSLEAERASRAERDSALETLQGQLEEKAQELGHSQSAlasaqrelaafRTKVQDHSKAEDEWKAQVARGRQEAE- 1221
Cdd:PTZ00121  1577 NMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEA-----------KIKAEELKKAEEEKKKVEQLKKKEAEe 1645

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1222 -RKNSLISSLEEEVSILNRQVLEKEGESKELKRLVMAESEKSQKLEERLRlLQAETASNSARAAERSSALREEVQSLREE 1300
Cdd:PTZ00121  1646 kKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALK-KEAEEAKKAEELKKKEAEEKKKAEELKKA 1724

                          730       740
                   ....*....|....*....|....*...
gi 1370459521 1301 AEKQRVASENLRQELTSQAERAEELGQE 1328
Cdd:PTZ00121  1725 EEENKIKAEEAKKEAEEDKKKAEEAKKD 1752
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 525-1365 3.94e-20

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 98.22  E-value: 3.94e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  525 KQQAKEKQAQLAQTLQQQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEATRQDHAQQLATAAEEREASLRERDAALK 604
Cdd:TIGR02169  172 KEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAERYQALLKEKREYEGYELLKEKEALERQKEAIERQLASLEE 251

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  605 QLEALEK---EKAAKLEILQQQL-QVANEARDSAQTSVTQAQREKAELSRKVEELQACVETARQEQHEAQAQVAELELQL 680
Cdd:TIGR02169  252 ELEKLTEeisELEKRLEEIEQLLeELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEI 331

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  681 RSEQQKATEKER----VAQEKDQLQEQLQALKESLKVTKGSLEEEKRRAA----------DALEEQQRCISELKAETRSL 746
Cdd:TIGR02169  332 DKLLAEIEELEReieeERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAetrdelkdyrEKLEKLKREINELKRELDRL 411

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  747 VEQHKRERKELEEERAGRKGLEARLQQLgeahQAETEVLRRELAEamaaqhtAESECEQLVKEVAAWRERYEDSQQEEAQ 826
Cdd:TIGR02169  412 QEELQRLSEELADLNAAIAGIEAKINEL----EEEKEDKALEIKK-------QEWKLEQLAADLSKYEQELYDLKEEYDR 480

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  827 YgamfQEQLMTLKEECEKARQELQEAKEKVAGIESHSELQISRQQNELAelhanLARALQQVQEK-----EVRAQKLADD 901
Cdd:TIGR02169  481 V----EKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVHG-----TVAQLGSVGERyataiEVAAGNRLNN 551

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  902 LSTLQEKMAATSKEVARletlVRKAGE------QQETASRELVKEPARAG---------DRQPEWleEQQGRQFCSTQAA 966
Cdd:TIGR02169  552 VVVEDDAVAKEAIELLK----RRKAGRatflplNKMRDERRDLSILSEDGvigfavdlvEFDPKY--EPAFKYVFGDTLV 625

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  967 LQAMEREAEQMGN-ELERLRAALMESQGQQQEERGQQEREVARLTQERGRAQADLALEKAARAELEmRLQNALNEQRVEF 1045
Cdd:TIGR02169  626 VEDIEAARRLMGKyRMVTLEGELFEKSGAMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELS-SLQSELRRIENRL 704

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1046 ATLQEALAHALTEKEGKDQELAKLRGLEAAQIKELEELRQTVKQLKEQLAKKEKEhasgsgaQSEAAGRTEPTGPKLEAL 1125
Cdd:TIGR02169  705 DELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSE-------LKELEARIEELEEDLHKL 777

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1126 RAEVSKLEQQCQKQQEqaDSLERSLEAERASRAERDSALETLQGQLEEKAQELGHSQSALASAQRELAAFRTKVQDHSKA 1205
Cdd:TIGR02169  778 EEALNDLEARLSHSRI--PEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKE 855

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1206 EDEWKAQVARGRQEAERKNSLISSLEEEVSILNRQVLEKEGESKELKRLVMAESEKSQKLEERLRLLQAETASNSARAAE 1285
Cdd:TIGR02169  856 IENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSE 935

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1286 RSSALREEVQSLREEAEKQRVASEnlRQELTSQAERAEELG----QELKAWQEKFFQKEQALSTLQLEHTSTQALVSELL 1361
Cdd:TIGR02169  936 IEDPKGEDEEIPEEELSLEDVQAE--LQRVEEEIRALEPVNmlaiQEYEEVLKRLDELKEKRAKLEEERKAILERIEEYE 1013


                   ....
gi 1370459521 1362 PAKH 1365
Cdd:TIGR02169 1014 KKKR 1017
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1015-1731 6.70e-20

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 97.43  E-value: 6.70e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1015 RAQADLALEKAARAELEMRLQN--ALNEQRVEFATLQEALAHA-----LTEKEGKDQELAKLRGLEAAQIKELEELRQTV 1087
Cdd:TIGR02168  183 RTRENLDRLEDILNELERQLKSleRQAEKAERYKELKAELRELelallVLRLEELREELEELQEELKEAEEELEELTAEL 262

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1088 KQLKEQLAKKEKEHASGSGAQSEAAGRteptgpkLEALRAEVSKLEQQCQKQQEQADSLERSLEAERASRAERDSALETL 1167
Cdd:TIGR02168  263 QELEEKLEELRLEVSELEEEIEELQKE-------LYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDEL 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1168 QGQLEEKAQELGHSQSALASAQRELAAFRTKVQDHSKAEDEWkaqvargRQEAERKNSLISSLEEEVSILNRQVLEKEGE 1247
Cdd:TIGR02168  336 AEELAELEEKLEELKEELESLEAELEELEAELEELESRLEEL-------EEQLETLRSKVAQLELQIASLNNEIERLEAR 408

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1248 SKELK-RLVMAESEKSQKLEERLRLLQAETASNSARAAERSSALREEVQSLREEAEKQRVASENLRQELTSQAERAEELG 1326
Cdd:TIGR02168  409 LERLEdRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQ 488

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1327 QELKAWQ------EKFFQKEQALSTLQLEHTSTQALVSELLPAKH---------LCQQLQAEQAAAEKRHREELEQSKQA 1391
Cdd:TIGR02168  489 ARLDSLErlqenlEGFSEGVKALLKNQSGLSGILGVLSELISVDEgyeaaieaaLGGRLQAVVVENLNAAKKAIAFLKQN 568

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1392 AGGLRAELLRAQRELGELIPLRQKVAEQERTAQQLRAEKASYAEQLSM--------------LKKAHGLLAEENRGL--- 1454
Cdd:TIGR02168  569 ELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKalsyllggvlvvddLDNALELAKKLRPGYriv 648

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1455 ----------------GERANLGRQFLEVELDQAREKyVQELAAVRADAETRLAEVQREAQSTARELEVMTAKYEGAKVK 1518
Cdd:TIGR02168  649 tldgdlvrpggvitggSAKTNSSILERRREIEELEEK-IEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQ 727

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1519 VLEER---QRFQEERQKLTAQVEQLEVFQREQTKQVEELSKKLADSDQASKVQQQKLKAVQAQGGESQQEAQRLQAQLNE 1595
Cdd:TIGR02168  728 ISALRkdlARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDE 807

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1596 LQAQLSQKEQAAEHYKLQMEKAKTHYDAKKqqnqelqeqlRSLEQLQKENKELRAEAERLGHELQQAGLKTKEAEQTCRH 1675
Cdd:TIGR02168  808 LRAELTLLNEEAANLRERLESLERRIAATE----------RRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEA 877

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1370459521 1676 LTAQVRSLEAQVAHADQQLRDLGKFQVATDALKSREPQAKPQLDLSIDSLDLSCEE 1731
Cdd:TIGR02168  878 LLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEG 933
PTZ00121 PTZ00121
MAEBL; Provisional
 517-1250 1.09e-19

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 97.13  E-value: 1.09e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  517 QDQELAGLKQQAKEKQAQLAQTLQQQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEATRQDHAQQLATAAEEREASL 596
Cdd:PTZ00121  1077 KDFDFDAKEDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAEDAKRVEI 1156

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  597 -RERDAALKQLEALEKEKAAKLEILQQQLQV--ANEARDSAQTSVTQAQReKAELSRKVEElqacVETARQEQHEAQAQV 673
Cdd:PTZ00121  1157 aRKAEDARKAEEARKAEDAKKAEAARKAEEVrkAEELRKAEDARKAEAAR-KAEEERKAEE----ARKAEDAKKAEAVKK 1231

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  674 AElELQLRSEQQKATEKERVAQEKDQLQEQLQAlkeslkvtkgslEEEKRRAADALEEQQRCISELKAETRSLVEQHKRE 753
Cdd:PTZ00121  1232 AE-EAKKDAEEAKKAEEERNNEEIRKFEEARMA------------HFARRQAAIKAEEARKADELKKAEEKKKADEAKKA 1298

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  754 RKELEEERAGRKGLEAR----LQQLGEAHQAETEVLRRELAEAMAAQHTAESECEQLVKEVAAWRERYE--DSQQEEAQY 827
Cdd:PTZ00121  1299 EEKKKADEAKKKAEEAKkadeAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEaaEKKKEEAKK 1378

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  828 GAmfqEQLMTLKEECEKARQELQEAKEKVAGIESHSELQISRQQNELAELHANLARALQQVQEKEVRAQKladdlstlQE 907
Cdd:PTZ00121  1379 KA---DAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKK--------AD 1447

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  908 KMAATSKEVARLETLVRKAGEQQETASRELVKEPARAGDRQPEWLEEQQGRQFCSTQAALQAME----REAEQMGNELER 983
Cdd:PTZ00121  1448 EAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKadeaKKAEEAKKADEA 1527

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  984 LRAALMESQGQQQEERGQQEREVARLTQERGRAQADLALEKAARAELE--MRLQNALNEQRVEFATLQEALAHALTEKEG 1061
Cdd:PTZ00121  1528 KKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDknMALRKAEEAKKAEEARIEEVMKLYEEEKKM 1607

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1062 KDQELAKLR--GLEAAQIKELEELRQTVKQLKEQLAKKEKEHASGSGAQSEAAGRTEPTGPKLEALRAEVSKLEQQCQKQ 1139
Cdd:PTZ00121  1608 KAEEAKKAEeaKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDE 1687

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1140 QEQADSLERslEAERASRAERdsaLETLQGQLEEKAQELghsqsalasaQRELAAFRTKVQDHSKAEDEWKAQVARGRQE 1219
Cdd:PTZ00121  1688 KKAAEALKK--EAEEAKKAEE---LKKKEAEEKKKAEEL----------KKAEEENKIKAEEAKKEAEEDKKKAEEAKKD 1752

                          730       740       750
                   ....*....|....*....|....*....|.
gi 1370459521 1220 AERKNSLISSLEEEVSILNRQVLEKEGESKE 1250
Cdd:PTZ00121  1753 EEEKKKIAHLKKEEEKKAEEIRKEKEAVIEE 1783
PTZ00121 PTZ00121
MAEBL; Provisional
 1008-1670 1.78e-18

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 93.28  E-value: 1.78e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1008 RLTQERGRAQADLALEKAARAELEMRLQNALNEQRVEFATLQEALAHALTEKEGKDQELAKlrglEAAQIKELEELRQTV 1087
Cdd:PTZ00121  1110 KAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAEDAKRVEIARKAEDARKAEEAR----KAEDAKKAEAARKAE 1185

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1088 KQLKEQLAKKEKEhasgsGAQSEAAGRTEPTGPKLEALRAEVSKLEQQCQKQQEQADSLERSLEAERASRAERDSALETL 1167
Cdd:PTZ00121  1186 EVRKAEELRKAED-----ARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEA 1260

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1168 QGQLEEKAQELGHSQSALASAQRELAAFRTKVQDHSKAEDEWKAQVARGRQEAERKNSLISSLEEEVSILNRQVLEKEGE 1247
Cdd:PTZ00121  1261 RMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEE 1340

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1248 SKELKRLVMAESEKSQKleerlrllQAETASNSARAAE-RSSALREEVQSLREEAEKQRVASENLR--QELTSQAERAEE 1324
Cdd:PTZ00121  1341 AKKAAEAAKAEAEAAAD--------EAEAAEEKAEAAEkKKEEAKKKADAAKKKAEEKKKADEAKKkaEEDKKKADELKK 1412

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1325 LGQELKAWQEKFFQKEQALSTLQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKRHREELEQSKQAAGGLRAELLRAQ- 1403
Cdd:PTZ00121  1413 AAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKa 1492

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1404 RELGELIPLRQKVAEQERTAQQLR-AEKASYAEQLSMLKKAHGllAEENRGLGERANLGRQFLEVELDQAREKYVQE--- 1479
Cdd:PTZ00121  1493 EEAKKKADEAKKAAEAKKKADEAKkAEEAKKADEAKKAEEAKK--ADEAKKAEEKKKADELKKAEELKKAEEKKKAEeak 1570

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1480 LAAVRADAETRLAEVQREAQStARELEVMTAKYEGAKVKVlEERQRFQEERQKlTAQVEQLEvfqrEQTKQVEELSKKLA 1559
Cdd:PTZ00121  1571 KAEEDKNMALRKAEEAKKAEE-ARIEEVMKLYEEEKKMKA-EEAKKAEEAKIK-AEELKKAE----EEKKKVEQLKKKEA 1643

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1560 DSDQASKVQQQKLKAVQAQGGESQQEAQRLQAQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKqqnqELQEQLRSLE 1639
Cdd:PTZ00121  1644 EEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKK----KEAEEKKKAE 1719

                          650       660       670
                   ....*....|....*....|....*....|.
gi 1370459521 1640 QLQKENKELRAEAERLGHELQQAGLKTKEAE 1670
Cdd:PTZ00121  1720 ELKKAEEENKIKAEEAKKEAEEDKKKAEEAK 1750
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 223-900 5.90e-14

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 77.96  E-value: 5.90e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  223 LADERSNRDELELELAENRKLLTEKDAQIAMMQQRIDrlALLNEKQAASPLEPKELEELRDKNESLTMRLHETLKQCQdl 302
Cdd:pfam12128  246 LQQEFNTLESAELRLSHLHFGYKSDETLIASRQEERQ--ETSAELNQLLRTLDDQWKEKRDELNGELSAADAAVAKDR-- 321

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  303 ktekSQMDRKINQLSEENGDLSFKLREFASHLQQLQDALNELTEEHSKATQEWLEKQAQLEKELSAALQDkkcleeknei 382
Cdd:pfam12128  322 ----SELEALEDQHGAFLDADIETAAADQEQLPSWQSELENLEERLKALTGKHQDVTAKYNRRRSKIKEQ---------- 387

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  383 LQGKLSQLEEHLSQLQDNPPQEKGEVLGDVLQLETLKQEAATLAANNtqlqARVEMLETERGQQEAKLLAERGHFEEEkq 462
Cdd:pfam12128  388 NNRDIAGIKDKLAKIREARDRQLAVAEDDLQALESELREQLEAGKLE----FNEEEYRLKSRLGELKLRLNQATATPE-- 461

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  463 qlssLITDLQSSISNLSQAKEELEQAsqahgarlTAQVASLTSELTTLNATIQQQDQELAGLKQQAKEKQAQLAQTLQQQ 542
Cdd:pfam12128  462 ----LLLQLENFDERIERAREEQEAA--------NAEVERLQSELRQARKRRDQASEALRQASRRLEERQSALDELELQL 529

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  543 EQASQGLRHqveQLSSSLKQKEQQLKEVAEKQEATRQDHAQQLATAAEEREASLRERDAALKQLEAleKEKAAKLEILQQ 622
Cdd:pfam12128  530 FPQAGTLLH---FLRKEAPDWEQSIGKVISPELLHRTDLDPEVWDGSVGGELNLYGVKLDLKRIDV--PEWAASEEELRE 604

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  623 QLQVANEARDSAQTSVTQAQREKAELSRKVEELQACVETARQEQHEAQAQVAELELQLRSEQQKATEKerVAQEKDQLQE 702
Cdd:pfam12128  605 RLDKAEEALQSAREKQAAAEEQLVQANGELEKASREETFARTALKNARLDLRRLFDEKQSEKDKKNKA--LAERKDSANE 682

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  703 QLQALKESLKVTKGSLEeekrraaDALEEQQRCISELKaetrslVEQHKRERKELEEERAGRKGLEARLQQLGEAHQAET 782
Cdd:pfam12128  683 RLNSLEAQLKQLDKKHQ-------AWLEEQKEQKREAR------TEKQAYWQVVEGALDAQLALLKAAIAARRSGAKAEL 749

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  783 EVLRRELAEAMAAQHTAE---SECEQLVKEVAAWRERYEDSQQEEAQYGAMFQEQLMT----LKEECEKARQELQEAKEK 855
Cdd:pfam12128  750 KALETWYKRDLASLGVDPdviAKLKREIRTLERKIERIAVRRQEVLRYFDWYQETWLQrrprLATQLSNIERAISELQQQ 829

                          650       660       670       680
                   ....*....|....*....|....*....|....*....|....*
gi 1370459521  856 VAGIESHSELQISRQQNELAELHANLARALQQVQEKEVRAQKLAD 900
Cdd:pfam12128  830 LARLIADTKLRRAKLEMERKASEKQQVRLSENLRGLRCEMSKLAT 874
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 566-1269 5.35e-13

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 74.87  E-value: 5.35e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  566 QLKEVAEKQEATRQDHAQQLATAAEEREASLRERDAALKQLEALEKEKAA-KLEILQQQLQVAN--EARDSAQTSVTQAQ 642
Cdd:pfam12128  213 PPKSRLNRQQVEHWIRDIQAIAGIMKIRPEFTKLQQEFNTLESAELRLSHlHFGYKSDETLIASrqEERQETSAELNQLL 292

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  643 REK-AELSRKVEELQACVETARQEQHEAQAQVAELELQLRSEQQKATEKERVAQEK-DQLQEQLQALKESLKVTKGSL-- 718
Cdd:pfam12128  293 RTLdDQWKEKRDELNGELSAADAAVAKDRSELEALEDQHGAFLDADIETAAADQEQlPSWQSELENLEERLKALTGKHqd 372

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  719 --EEEKRRAADALEEQQRCISELKAETRslveqhkrerkeleeeragrKGLEARLQQLGEAhQAETEVLRRELAEAMAAQ 796
Cdd:pfam12128  373 vtAKYNRRRSKIKEQNNRDIAGIKDKLA--------------------KIREARDRQLAVA-EDDLQALESELREQLEAG 431

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  797 HTAESECEQLVKEVAAWreryEDSQQEEAQYGAMFQEQLMTLKEECEKARQELQEAKEKVagieshselqiSRQQNELAE 876
Cdd:pfam12128  432 KLEFNEEEYRLKSRLGE----LKLRLNQATATPELLLQLENFDERIERAREEQEAANAEV-----------ERLQSELRQ 496

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  877 LHANLARALQQVQEKEVRAQKLADDLSTLQEKMAATSKEVarLETLVRKAGEQQETASRELVKEPARAGDRQPEWLEEQ- 955
Cdd:pfam12128  497 ARKRRDQASEALRQASRRLEERQSALDELELQLFPQAGTL--LHFLRKEAPDWEQSIGKVISPELLHRTDLDPEVWDGSv 574

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  956 -QGRQFCSTQAALQAMER-EAEQMGNELERLRAALMESQGQQQEERGQQEREVARLTQERGRAQADLALEKAARAELEMR 1033
Cdd:pfam12128  575 gGELNLYGVKLDLKRIDVpEWAASEEELRERLDKAEEALQSAREKQAAAEEQLVQANGELEKASREETFARTALKNARLD 654

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1034 LQNALNEQRVEFATLQEALahalteKEGKDQELAKLRGLEAAQIKELEELRQTVKQLKEQLakkekehasgsgaqseaag 1113
Cdd:pfam12128  655 LRRLFDEKQSEKDKKNKAL------AERKDSANERLNSLEAQLKQLDKKHQAWLEEQKEQK------------------- 709

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1114 rTEPTGPKLEALRAEVSKLEQQCqkqqeqaDSLERSLEAERASRAERDSALETlqgQLEEKAQELGHSQSALASAQRELA 1193
Cdd:pfam12128  710 -REARTEKQAYWQVVEGALDAQL-------ALLKAAIAARRSGAKAELKALET---WYKRDLASLGVDPDVIAKLKREIR 778

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1194 AFRTKV----QDHSKAEDEWKAQVARGRQEAERKNSLISSLEEEVSILNRQVLEKEGESKELKRLVMAESEKSQKLEERL 1269
Cdd:pfam12128  779 TLERKIeriaVRRQEVLRYFDWYQETWLQRRPRLATQLSNIERAISELQQQLARLIADTKLRRAKLEMERKASEKQQVRL 858
MARTX_Nterm NF012221
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...
 406-647 2.73e-09

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.


Pssm-ID: 467957 [Multi-domain]  Cd Length: 1848  Bit Score: 62.93  E-value: 2.73e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  406 GEVLGDVLQLETLKQEAATLAANNTQLQARVEMLetergQQEAKLLAERGHFEEEKQQLSSLITDLQSSISNLSQAKeeL 485
Cdd:NF012221  1528 GYILDNVVATSESSQQADAVSKHAKQDDAAQNAL-----ADKERAEADRQRLEQEKQQQLAAISGSQSQLESTDQNA--L 1600

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  486 EQASQAHGARLTAQVASLTSELTTLNATIQQ---QDQELAGLKQQAKEKQAQLAQTLQQQEQASQGL--RHQVEQLSSSL 560
Cdd:NF012221  1601 ETNGQAQRDAILEESRAVTKELTTLAQGLDAldsQATYAGESGDQWRNPFAGGLLDRVQEQLDDAKKisGKQLADAKQRH 1680

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  561 KQKEQQLKEVAEKQEA--TRQDHAQQLATAAEER---EASLRERDAALKQLEALEKEKAAKLeilqqqlqVANEARDSAQ 635
Cdd:NF012221  1681 VDNQQKVKDAVAKSEAgvAQGEQNQANAEQDIDDakaDAEKRKDDALAKQNEAQQAESDANA--------AANDAQSRGE 1752

                          250
                   ....*....|..
gi 1370459521  636 TSVTQAQREKAE 647
Cdd:NF012221  1753 QDASAAENKANQ 1764
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
662-1192 2.97e-08

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 59.16  E-value: 2.97e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  662 ARQEQHEAQAQVAELElQLRSEQQKATEKERVAQEKDQLQEQLQALKESLKVTKG-----SLEEEKRRAADALEEQQRCI 736
Cdd:COG4913    240 AHEALEDAREQIELLE-PIRELAERYAAARERLAELEYLRAALRLWFAQRRLELLeaeleELRAELARLEAELERLEARL 318

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  737 SELKAETRSLVEQHkrerkeleeerAGRKGleARLQQLgeahQAETEVLRRELAEAMAAQHTAESECEQLVKEVAAWRER 816
Cdd:COG4913    319 DALREELDELEAQI-----------RGNGG--DRLEQL----EREIERLERELEERERRRARLEALLAALGLPLPASAEE 381

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  817 YEDSQQEEAQYGAMFQEQLMTLKEECEKARQELQEAKEKVAGIEshSELQISRQQN-----ELAELHANLARALQ----- 886
Cdd:COG4913    382 FAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELE--AEIASLERRKsnipaRLLALRDALAEALGldeae 459

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  887 --------QVQEKE-------------------------------VRAQKLADDLSTLQEKMAATSKEVARLE--TLVRK 925
Cdd:COG4913    460 lpfvgeliEVRPEEerwrgaiervlggfaltllvppehyaaalrwVNRLHLRGRLVYERVRTGLPDPERPRLDpdSLAGK 539

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  926 ageqqetasreLVKEPARAGDrqpeWLEEQQGRQF----CSTQAALQAMER---EAEQMGNELERLRAALMESQGQQQEE 998
Cdd:COG4913    540 -----------LDFKPHPFRA----WLEAELGRRFdyvcVDSPEELRRHPRaitRAGQVKGNGTRHEKDDRRRIRSRYVL 604

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  999 RGQQEREVARLTQERGRAQADLALEKAARAELEmRLQNALNEQRVEFATLQEaLAHALTEKEGKDQELAKLRgleaAQIK 1078
Cdd:COG4913    605 GFDNRAKLAALEAELAELEEELAEAEERLEALE-AELDALQERREALQRLAE-YSWDEIDVASAEREIAELE----AELE 678

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1079 ELEELRQTVKQLKEQLAKKEKEHASGSGAQSEAAGRTEPTGPKLEALRAEVSKLEQQCQKQQEQADSLERSLEAERASRA 1158
Cdd:COG4913    679 RLDASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAA 758

                          570       580       590
                   ....*....|....*....|....*....|....
gi 1370459521 1159 ERDSALETLQGQLEEKAQELghsQSALASAQREL 1192
Cdd:COG4913    759 LGDAVERELRENLEERIDAL---RARLNRAEEEL 789
MARTX_Nterm NF012221
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...
 253-656 7.47e-07

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.


Pssm-ID: 467957 [Multi-domain]  Cd Length: 1848  Bit Score: 54.84  E-value: 7.47e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  253 MMQQRIDRLALLNEKQAASPLEPKeLEELRDKNESLTMRLHETLKQCQDLK-TEKSQMDRKINQLSEENGDLSFKLREFA 331
Cdd:NF012221  1457 LTAGEVIALSFDFARRAGLSTNNG-IEVLWNGEVVFASSGDASAWQQKTLKlTAKAGSNRLEFKGTGHNDGLGYILDNVV 1535

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  332 --SHLQQLQDALNELTEEhSKATQEwlekqaqlekelsaALQDKKCLEEKNEILQGKLSQLEEHLSQLQ---DNPPQEKG 406
Cdd:NF012221  1536 atSESSQQADAVSKHAKQ-DDAAQN--------------ALADKERAEADRQRLEQEKQQQLAAISGSQsqlESTDQNAL 1600

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  407 EVLGDVlQLETLKQEAATLAANNTQLQARVEMLET------ERGQQeakllaERGHFEEekqqlsSLITDLQSSISNLSQ 480
Cdd:NF012221  1601 ETNGQA-QRDAILEESRAVTKELTTLAQGLDALDSqatyagESGDQ------WRNPFAG------GLLDRVQEQLDDAKK 1667

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  481 -AKEELEQASQAHGARLT-AQVASLTSELTTLNATIQQQDQELAGlkQQAKEKQAQLAQTLQQQEQASQglrhQVEQLSS 558
Cdd:NF012221  1668 iSGKQLADAKQRHVDNQQkVKDAVAKSEAGVAQGEQNQANAEQDI--DDAKADAEKRKDDALAKQNEAQ----QAESDAN 1741

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  559 SLKQKEQQLKEVAEKQEATRQDHAQQLATAAEEREASLRERDAALKQL---EALEKEKAAK-LEILQQQLQVANEARDSA 634
Cdd:NF012221  1742 AAANDAQSRGEQDASAAENKANQAQADAKGAKQDESDKPNRQGAAGSGlsgKAYSVEGVAEpGSHINPDSPAAADGRFSE 1821

                          410       420
                   ....*....|....*....|..
gi 1370459521  635 QTSvTQAQREKAELSRKVEELQ 656
Cdd:NF012221  1822 GLT-EQEQEALEGATNAVNRLQ 1842
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 832-1042 2.24e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 52.07  E-value: 2.24e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  832 QEQLMTLKEECEKARQELQEAKEKVAGIEShselQISRQQNELAELHANLARALQQVQEKEVRAQKLADDLSTLQEKMAA 911
Cdd:COG4942     26 EAELEQLQQEIAELEKELAALKKEEKALLK----QLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEA 101

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  912 TSKEVARLETLVRKAGEQQETASRELVKEPARAGDRQpEWLE------EQQGRQFCSTQAALQAMEREAEQMGNELERLR 985
Cdd:COG4942    102 QKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRL-QYLKylaparREQAEELRADLAELAALRAELEAERAELEALL 180

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1370459521  986 AALMESQGQQQEERGQQEREVARLTQERGRAQADLALEKAARAELEMRLQNALNEQR 1042
Cdd:COG4942    181 AELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAA 237
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1022-1661 7.15e-06

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 51.51  E-value: 7.15e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1022 LEKAARAELEMRLQNALNEQRVEFATLQEALAHALTEKEG----KDQELAKLRGLEAAQIKELEELRQTVKQLKEQLAKK 1097
Cdd:pfam02463  159 EEEAAGSRLKRKKKEALKKLIEETENLAELIIDLEELKLQelklKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEER 238

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1098 EKEhasgsgaqseaagrtepTGPKLEALRAEVSKLEQQCQKQQEQADSLERSLEAERASRAERDSALETLQGQLEEKAQE 1177
Cdd:pfam02463  239 IDL-----------------LQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSE 301

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1178 LGHSQSALASAQRELAAFRTKVQDHSKAEDEWKAQVARGRQEAERKNSLISSLEEEVSILNRQVLEKEGESKELKRLVMA 1257
Cdd:pfam02463  302 LLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKL 381

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1258 ESEKSQKLEERLRLLQAETASNSARAAERSSALREEVQSLREEAEKQRVASENLRQELTSQAERAEELGQELKAWQEKFF 1337
Cdd:pfam02463  382 ESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLL 461

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1338 QKEQALSTLQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKRHREELE----QSKQAAGGLRAELLRAQRELGELIPLR 1413
Cdd:pfam02463  462 KDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKvllaLIKDGVGGRIISAHGRLGDLGVAVENY 541

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1414 QKVAEQERTAQQLRAEKASYAEQ-----LSMLKKAHGLLAEENRGLGERANLGRQFLEVELDQAREKYVQELAAVRADAE 1488
Cdd:pfam02463  542 KVAISTAVIVEVSATADEVEERQklvraLTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKR 621

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1489 TRLAEVQREAQ----------------STARELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVEQL---EVFQREQTK 1549
Cdd:pfam02463  622 AKVVEGILKDTeltklkesakakesglRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELakeEILRRQLEI 701

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1550 QVEELSKKLADSDQASKVQQQKLKAVQAQGGESQQEAQRLQAQLNELQAQL---SQKEQAAEHYKLQMEKAKTHYDAKKQ 1626
Cdd:pfam02463  702 KKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEeksRLKKEEKEEEKSELSLKEKELAEERE 781

                          650       660       670
                   ....*....|....*....|....*....|....*
gi 1370459521 1627 QNQELQEQLRSLEQLQKENKELRAEAERLGHELQQ 1661
Cdd:pfam02463  782 KTEKLKVEEEKEEKLKAQEEELRALEEELKEEAEL 816
PRK09039 PRK09039
peptidoglycan -binding protein;
866-988 8.75e-05

peptidoglycan -binding protein;


Pssm-ID: 181619 [Multi-domain]  Cd Length: 343  Bit Score: 46.88  E-value: 8.75e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  866 QISRQQNELAELHANLARALQQVQEKEVRAQKLADDLSTLQEKMAATSKEVARLETL-VRKAGEQQETASRELVKEPARA 944
Cdd:PRK09039    47 EISGKDSALDRLNSQIAELADLLSLERQGNQDLQDSVANLRASLSAAEAERSRLQALlAELAGAGAAAEGRAGELAQELD 126

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1370459521  945 --------GDRQPEWLEEQQG---RQFCSTQAALQAMEREAEQMGNELE----RLRAAL 988
Cdd:PRK09039   127 sekqvsarALAQVELLNQQIAalrRQLAALEAALDASEKRDRESQAKIAdlgrRLNVAL 185
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 1764-2034 3.68e-04

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 45.93  E-value: 3.68e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1764 PDGTSVPGEPASPISQRlPPKVESLESLYFTPIPARSQA--PLESSLDSLGDVFLDSGRKTRSARRRTTQIINITMTKKL 1841
Cdd:PHA03307   192 EPPPSTPPAAASPRPPR-RSSPISASASSPAPAPGRSAAddAGASSSDSSSSESSGCGWGPENECPLPRPAPITLPTRIW 270

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1842 DVEEPDsaNSSFYSTRSAPASQASLRATSSTQSLARLGSPDYGNSALLSLPGYRP-----TTRSSARRSQAGVSSGAPPG 1916
Cdd:PHA03307   271 EASGWN--GPSSRPGPASSSSSPRERSPSPSPSSPGSGPAPSSPRASSSSSSSREsssssTSSSSESSRGAAVSPGPSPS 348

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1917 RNsfymGTCQDEPeqldDWNRIAELQQRnrvCPPHLKTCYPLESRPSlslgtitdeemktgdpqETLRRASMQ---PIQI 1993
Cdd:PHA03307   349 RS----PSPSRPP----PPADPSSPRKR---PRPSRAPSSPAASAGR-----------------PTRRRARAAvagRARR 400

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|.
gi 1370459521 1994 AEGTGITTRQQRKRVSLEPHQGPGTPESKkatscfPRPMTP 2034
Cdd:PHA03307   401 RDATGRFPAGRPRPSPLDAGAASGAFYAR------YPLLTP 435
MARTX_Nterm NF012221
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...
 1415-1675 9.12e-03

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.


Pssm-ID: 467957 [Multi-domain]  Cd Length: 1848  Bit Score: 41.36  E-value: 9.12e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1415 KVAEQERTAQQLRAEKASYAEQLSMLKKahgllaEENRGLGERAnlGRQF-LEVELDQAREKYVQ-ELAAVRADAEtrla 1492
Cdd:NF012221  1549 KHAKQDDAAQNALADKERAEADRQRLEQ------EKQQQLAAIS--GSQSqLESTDQNALETNGQaQRDAILEESR---- 1616

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1493 EVQREAQSTARELEVMTAKYEGAKVKVLEERQRFQEeRQKLTAQvEQLEVFQREQTKQVEELSKKLADSDQASKVQQQKL 1572
Cdd:NF012221  1617 AVTKELTTLAQGLDALDSQATYAGESGDQWRNPFAG-GLLDRVQ-EQLDDAKKISGKQLADAKQRHVDNQQKVKDAVAKS 1694

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1573 KAVQAQGGESQQEAQrLQAQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQELQeqlrslEQLQKENKELRAEA 1652
Cdd:NF012221  1695 EAGVAQGEQNQANAE-QDIDDAKADAEKRKDDALAKQNEAQQAESDANAAANDAQSRGEQ------DASAAENKANQAQA 1767

                          250       260
                   ....*....|....*....|...
gi 1370459521 1653 ErlghelqQAGLKTKEAEQTCRH 1675
Cdd:NF012221  1768 D-------AKGAKQDESDKPNRQ 1783
 
Name Accession Description Interval E-value
HkD_NuMA cd22224
Hook domain found in nuclear mitotic apparatus protein (NuMA) and similar proteins; NuMA, also ...
 6-152 4.65e-58

Hook domain found in nuclear mitotic apparatus protein (NuMA) and similar proteins; NuMA, also called nuclear mitotic apparatus protein 1, or nuclear matrix protein-22 (NMP-22), or SP-H antigen, is a microtubule (MT)-binding protein that plays a role in the formation and maintenance of the spindle poles, and the alignment and segregation of chromosomes during mitotic cell division. The model corresponds to the N-terminal conserved globular Hook domain of NuMA, which folds as a variant of the helical calponin homology (CH) domain. It directly binds dynein light intermediate chains LIC1 and LIC2 through a conserved hydrophobic patch shared among other Hook adaptors.


Pssm-ID: 411795  Cd Length: 148  Bit Score: 197.41  E-value: 4.65e-58
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521    6 TRGAALLSWVNSLHVADPVEAVLQLQDCSIFIKIIDRIHGTEEGQQILKQPVSERLDFVCSFLQKNRKHPSSPECLVSAQ 85
Cdd:cd22224      2 TKAEALLSWVNSLKLDDPIESISQLQDGTILLKIIYKLKGEEEEEQILDLSVEERLEFISSFLEGDCRFNSSQGTLVSWQ 81

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1370459521   86 KVLEG--SELELAKMTMLLLYHSTMSSKSPrdWEQFEYKIQAELAVILKFVLDHEDGLNLNEDLENFLQ 152
Cdd:cd22224     82 KILQGenLELELAKVLLLLLYHSMMNNNLT--LEKLDYKTELELASILRFVLDNEDGLYLSEGLDKFLT 148
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 215-911 5.39e-27

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 120.93  E-value: 5.39e-27
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  215 QMRRLKKQLADERSNRDELELELAENRKLLTEKDAQIAMMQQRIDRL--ALLNEKQAASPLE------PKELEELRDKNE 286
Cdd:TIGR02168  240 ELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELqkELYALANEISRLEqqkqilRERLANLERQLE 319

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  287 SLTMRLHETLKQCQDLKTEKSQMDRKINQLSEENGDLSFKLREFASHLQQLQDALNELTEEH---SKATQEWLEKQAQLE 363
Cdd:TIGR02168  320 ELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLetlRSKVAQLELQIASLN 399

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  364 KELSAALQDKKCLEEKNEILQgklSQLEEHLSQLQDNPPQEKGEvlgdvlQLETLKQEAATLAANNTQLQARVEMLETER 443
Cdd:TIGR02168  400 NEIERLEARLERLEDRRERLQ---QEIEELLKKLEEAELKELQA------ELEELEEELEELQEELERLEEALEELREEL 470

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  444 GQQEAKLLAERGHFEEEKQQLSSLITDLQSSISNLSQAKEELEQASQAHGAR-LTAQVASLTSEL-----TTLNATIQ-- 515
Cdd:TIGR02168  471 EEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILgVLSELISVDEGYeaaieAALGGRLQav 550

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  516 ------QQDQELAGLKQQAKEK-------QAQLAQTLQQQEQASQGLRHQVEQLSSSLKQKEQ----------QLKEVAE 572
Cdd:TIGR02168  551 vvenlnAAKKAIAFLKQNELGRvtflpldSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKlrkalsyllgGVLVVDD 630

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  573 KQEATRQ----DHAQQLAT--------------AAEEREASLRERDAALKQLEALEKEKAAKLEILQQQLQVANEARDSA 634
Cdd:TIGR02168  631 LDNALELakklRPGYRIVTldgdlvrpggvitgGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEEL 710

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  635 QTSVTQAQREKAELSRKVEELQACVETARQEQHEAQAQVAELELQLRSEQQKAT------------------EKERVAQE 696
Cdd:TIGR02168  711 EEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEeleerleeaeeelaeaeaEIEELEAQ 790

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  697 KDQLQEQLQALKESLKVTKGSLEEEKRRAADALEEQQRCISELKAETRSLVEQHKRERKELEEERAGRKGLEaRLQQLGE 776
Cdd:TIGR02168  791 IEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIE-ELEELIE 869

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  777 AHQAETEVLRRELAEAMAAQHTAESECEQLVKEVAAWRERyedsqqeeaqygamfqeqLMTLKEECEKARQELQEAKEKV 856
Cdd:TIGR02168  870 ELESELEALLNERASLEEALALLRSELEELSEELRELESK------------------RSELRRELEELREKLAQLELRL 931

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1370459521  857 AGIeshsELQISRQQNELAELHA-NLARALQQVQEKEVRAQKLADDLSTLQEKMAA 911
Cdd:TIGR02168  932 EGL----EVRIDNLQERLSEEYSlTLEEAEALENKIEDDEEEARRRLKRLENKIKE 983
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 563-1331 5.57e-27

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 120.55  E-value: 5.57e-27
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  563 KEQQLKEVAEKQEATRQDHAQQLATAAEEREASL----RERDAALKQLEALEKEKAAKLEILQQQLQVANEARDSAQTSV 638
Cdd:TIGR02168  169 KYKERRKETERKLERTRENLDRLEDILNELERQLksleRQAEKAERYKELKAELRELELALLVLRLEELREELEELQEEL 248

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  639 TQAQREKAELSRKVEELQACVETARQEQHEAQAQVAELELQLrseQQKATEKERVAQEKDQLQEQLQALKESLKVTKGSL 718
Cdd:TIGR02168  249 KEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKEL---YALANEISRLEQQKQILRERLANLERQLEELEAQL 325

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  719 EEEKRR---AADALEEQQRCISELKAETRSLVEQHKRERKELEEERAGRKGLEARLQQLgeahQAETEVLRRELAEAMAA 795
Cdd:TIGR02168  326 EELESKldeLAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETL----RSKVAQLELQIASLNNE 401

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  796 QHTAESECEQLVKEVAAWRERYEDSQQEeaqygaMFQEQLMTLKEECEKARQELQEAKEKVAGIEShselQISRQQNELA 875
Cdd:TIGR02168  402 IERLEARLERLEDRRERLQQEIEELLKK------LEEAELKELQAELEELEEELEELQEELERLEE----ALEELREELE 471

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  876 ELHANLARALQQVQEKEVRA---QKLADDLSTLQEKMAATSKEVARLETLVRKAGEQQETASR-ELVKEPARAGDRQPEW 951
Cdd:TIGR02168  472 EAEQALDAAERELAQLQARLdslERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGyEAAIEAALGGRLQAVV 551

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  952 LEeqqgrqfcSTQAALQAMEREAEQmgnelERLRAALMEsqGQQQEERGQQEREVARLTQERGRAQADLALEKAArAELE 1031
Cdd:TIGR02168  552 VE--------NLNAAKKAIAFLKQN-----ELGRVTFLP--LDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFD-PKLR 615

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1032 MRLQNALNEQRVeFATLQEALAHALTEKEG-----KDQELAKLRGLEA-----------AQIKELEELRQTVKQLKEQLA 1095
Cdd:TIGR02168  616 KALSYLLGGVLV-VDDLDNALELAKKLRPGyrivtLDGDLVRPGGVITggsaktnssilERRREIEELEEKIEELEEKIA 694

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1096 KKEKEHASGSGAQSE-------AAGRTEPTGPKLEALRAEVSKLEQQCQKQQEQADSLERSLEAERASRAERDSALETLQ 1168
Cdd:TIGR02168  695 ELEKALAELRKELEEleeeleqLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAE 774

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1169 GQLEEKAQELGHSQSALASAQRELAAFRTKVQDHSKAEDEWKAQVARGRQEAERKNSLISSLEEEVSILNRQVLEKEGES 1248
Cdd:TIGR02168  775 EELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDI 854

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1249 KELKRLVMAESEKSQKLEERLRLLQAETASNSARAAERSSALREEVQSLReEAEKQRVASENLRQELTSQAERAEELGQE 1328
Cdd:TIGR02168  855 ESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELR-ELESKRSELRRELEELREKLAQLELRLEG 933


                   ...
gi 1370459521 1329 LKA 1331
Cdd:TIGR02168  934 LEV 936
NuMA_LGNBD cd22298
LGN binding domain (LGNBD) of nuclear mitotic apparatus protein (NuMA) and similar proteins; ...
 1888-1946 1.13e-26

LGN binding domain (LGNBD) of nuclear mitotic apparatus protein (NuMA) and similar proteins; NuMA, also called nuclear matrix protein-22 (NMP-22), nuclear mitotic apparatus protein 1 (NUMA1), or SP-H antigen, is a microtubule (MT)-binding protein that plays a role in the formation and maintenance of spindle poles and the alignment and segregation of chromosomes during mitotic cell division. It is involved in the establishment of mitotic spindle orientation during metaphase, and elongation during anaphase in a dynein-dynactin-dependent manner. NuMA, in complex with LGN, forms NuMA:LGN hetero-hexamers that promote spindle orientation. The model corresponds to the LGN binding domain (LGNBD) of NuMA. LGN (named for leu-gly-asn repeats) is also known as G protein signaling modulator 2.


Pssm-ID: 412093  Cd Length: 56  Bit Score: 104.22  E-value: 1.13e-26
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1370459521 1888 LLSLPGYRPTTRSSARRSQagvSSGAPPGRNSFYMGTCQDEPEQLDDWNRIAELQQRNR 1946
Cdd:cd22298      1 LLSLPGYRPSTRSSTRRSQ---SSSATGGRSTFYMGTCQDEPEHLDDWNRIAELQQRNR 56
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 559-1326 2.36e-25

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 115.54  E-value: 2.36e-25
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  559 SLKQKEQQLKEVAEKQEATRQDHAQQLATAAEEREASLRERDAALKQLEALEKEKAAKLEILQQQLQVANEARDSAQTSV 638
Cdd:TIGR02168  204 SLERQAEKAERYKELKAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEI 283

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  639 TQAQREKAELSRKVEELQACVETARQEQHEAQAQVAELELQLRSEQQKATEKERVAQEKDQLQEQLQALKESLKVTKGSL 718
Cdd:TIGR02168  284 EELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEEL 363

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  719 EEEKRRAADALEEQQRCISELKAETRSLVEQHKRERKELEEERAGRKGLEARLQQLgeahQAETEVLRRELAEamAAQHT 798
Cdd:TIGR02168  364 EAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERL----QQEIEELLKKLEE--AELKE 437

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  799 AESECEQLVKEVAAWRERYEDsqqeeaqygamFQEQLMTLKEECEKARQELQEAKEKVAGIESHSELQISRQQNelaelH 878
Cdd:TIGR02168  438 LQAELEELEEELEELQEELER-----------LEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQEN-----L 501

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  879 ANLARALQQVQEKevrAQKLADDLSTLQEKMAATSKEVARLETLVRKAGEQQETASRELVK------EPARAGDRQPEWL 952
Cdd:TIGR02168  502 EGFSEGVKALLKN---QSGLSGILGVLSELISVDEGYEAAIEAALGGRLQAVVVENLNAAKkaiaflKQNELGRVTFLPL 578

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  953 EEQQGRQFCSTQAALQAMEREAEQMGNELE----RLRAAL------------MESQGQQQEERGQQEREV---------- 1006
Cdd:TIGR02168  579 DSIKGTEIQGNDREILKNIEGFLGVAKDLVkfdpKLRKALsyllggvlvvddLDNALELAKKLRPGYRIVtldgdlvrpg 658

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1007 ----------ARLTQERGRAQADLALEKAARAELEMRLQNALNEQRVEFATLQEALAHALTEKEGKDQELAKLRGLEAAQ 1076
Cdd:TIGR02168  659 gvitggsaktNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARL 738

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1077 IKELEELRQTVKQLKEQLAKKEKEHASGSGAQSEAAGRTEPTGPKLEALRAEVSKLEQQCQKQQEQADSLERSLEAERAS 1156
Cdd:TIGR02168  739 EAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEE 818

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1157 RAERDSALETLQGQLEEKAQELGHSQSALASAQRELAAFRTKVQDHSKAEDEWKAQVARGRQEAERKNSLISSLEEEVSI 1236
Cdd:TIGR02168  819 AANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEE 898

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1237 LNRQVLEKEGESKELKRLVMAESEKSQKLEERLRLLQAETASNSARAAERSSALREEVQSLREEAEKQrvaSENLRQELT 1316
Cdd:TIGR02168  899 LSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDD---EEEARRRLK 975

                          810
                   ....*....|
gi 1370459521 1317 SQAERAEELG 1326
Cdd:TIGR02168  976 RLENKIKELG 985
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 470-1095 3.01e-25

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 114.65  E-value: 3.01e-25
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  470 DLQSSISNLSQAKEELEQASQAHgARLTAQVASLTSELTTLNATIQQQDQELAGLKQQAKEKQAQLAQTLQQQEQASQGL 549
Cdd:COG1196    226 EAELLLLKLRELEAELEELEAEL-EELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDI 304

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  550 RHQVEQLsSSLKQKEQQLKEVAEKQEATRQDHAQQLATAAEEREASLRERDAALKQLEALEKEKAAKLEILQQQLQVANE 629
Cdd:COG1196    305 ARLEERR-RELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEE 383

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  630 ARDSAQtsvtQAQREKAELSRKVEELQACVETARQEQHEAQAQVAELELQLRSEQQKATEKERVAQEKDQLQEQLQALKE 709
Cdd:COG1196    384 LAEELL----EALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEE 459

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  710 SLKVTKGSLEEEKRRAADALEEQQRCISELKAEtrslveqhkrerkeleeeragrkgLEARLQQLGEAHQAETEVLRREL 789
Cdd:COG1196    460 ALLELLAELLEEAALLEAALAELLEELAEAAAR------------------------LLLLLEAEADYEGFLEGVKAALL 515

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  790 AEAMAAQHtaeseceQLVKEVAAWRERYEDSQQEEAqyGAMFQEQLMTLKEECEKARQELQEAKEKVAGIESHSELQISR 869
Cdd:COG1196    516 LAGLRGLA-------GAVAVLIGVEAAYEAALEAAL--AAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARA 586

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  870 QQNELAELHANLARALQQVQEKEVRAQKLADDLSTLQEKMAATSKEVARLETLVRKAGEQQETASRELVKEPARAgdrqp 949
Cdd:COG1196    587 ALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGS----- 661

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  950 ewleeqqgrqfcSTQAALQAMEREAEQMGNELERLRAALMESQGQQQEERGQQEREVARLTQERGRAQADLALEKAARAE 1029
Cdd:COG1196    662 ------------LTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQ 729

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1370459521 1030 LEMRLQNALNEQRVEFATLQEALAHALTEKEGKDQELAKLRGLEA----------AQIKELEELRQTVKQLKEQLA 1095
Cdd:COG1196    730 LEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEReiealgpvnlLAIEEYEELEERYDFLSEQRE 805
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 215-937 4.12e-25

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 114.77  E-value: 4.12e-25
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  215 QMRRLKKQ------LADERSNRDELELELAENRKL-----LTEKDAQIAMMQQRIDRL-ALLNEKQAasplepkELEELR 282
Cdd:TIGR02168  201 QLKSLERQaekaerYKELKAELRELELALLVLRLEelreeLEELQEELKEAEEELEELtAELQELEE-------KLEELR 273

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  283 DKNESLTMRLHETLKQCQDLKTEKSQMDRKINQLSEEngdlsfklrefASHLQQLQDALNELTEEHSKATQEWLEKQAQL 362
Cdd:TIGR02168  274 LEVSELEEEIEELQKELYALANEISRLEQQKQILRER-----------LANLERQLEELEAQLEELESKLDELAEELAEL 342

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  363 EKELSAALQDKKCLEEKNEILQGKLSQLEEHLSQLQDNPPQEKGEVLGDVLQLETLKQEAATLAANNTQLQARVEMLETE 442
Cdd:TIGR02168  343 EEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQE 422

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  443 RGQ-----QEAKLLAERGHFEEEKQQLSSLITDLQSSISNLSQAKEELEQASQAHGArLTAQVASLTSELTTLNATIQQQ 517
Cdd:TIGR02168  423 IEEllkklEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDA-AERELAQLQARLDSLERLQENL 501

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  518 DQELAGLKQQAKEKqaqlaqtlqqqeqasQGLRHQVEQLSSSLKQKEQQLKEVAEKQEATRQDHAQQLATAAEEREASLR 597
Cdd:TIGR02168  502 EGFSEGVKALLKNQ---------------SGLSGILGVLSELISVDEGYEAAIEAALGGRLQAVVVENLNAAKKAIAFLK 566

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  598 ERDAALKQLEALEKEKAAKLEILQ-QQLQVANEARDSAQTSVTQAQREKAELS------RKVEELQACVETARQEQHEAQ 670
Cdd:TIGR02168  567 QNELGRVTFLPLDSIKGTEIQGNDrEILKNIEGFLGVAKDLVKFDPKLRKALSyllggvLVVDDLDNALELAKKLRPGYR 646

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  671 AQVAELELQLR-------------SEQQKATEKERVAQEKDQLQEQLQALKESLKVTKGS---LEEEKRRAADALEEQQR 734
Cdd:TIGR02168  647 IVTLDGDLVRPggvitggsaktnsSILERRREIEELEEKIEELEEKIAELEKALAELRKEleeLEEELEQLRKELEELSR 726

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  735 CISELKAETRSLVEQHKRERKELEEERAGRKGLEARLQQLgeahQAETEVLRRELAEAMAAQHTAESECEQLVKEVAAWR 814
Cdd:TIGR02168  727 QISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEEL----EERLEEAEEELAEAEAEIEELEAQIEQLKEELKALR 802

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  815 ERYEDSQQEEAQYGAMFQEQLMTLK------EECEKARQELQEAKEKVAGIESHSELQISRQQNELAELHANLARALQQV 888
Cdd:TIGR02168  803 EALDELRAELTLLNEEAANLRERLEslerriAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNER 882

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*....
gi 1370459521  889 QEKEVRAQKLADDLSTLQEKMAATSKEVARLETLVRKAGEQQETASREL 937
Cdd:TIGR02168  883 ASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRL 931
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 597-1194 6.99e-25

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 113.49  E-value: 6.99e-25
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  597 RERDAALKQLEALEKEKAAKLEILQQQLQVANEARDSAQTSVTQAQREKAELSRKVEELQACVETARQEQHEAQAQVAEL 676
Cdd:COG1196    207 RQAEKAERYRELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEA 286

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  677 ELQLRSEQQkatEKERVAQEKDQLQEQLQALKESLKvtkgSLEEEKRRAADALEEQQRCISELKAETRSLVEQHKRERKE 756
Cdd:COG1196    287 QAEEYELLA---ELARLEQDIARLEERRRELEERLE----ELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAE 359

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  757 LEEERAGRKGLEARLQQLgeahQAETEVLRRELAEAMAAQHTAESECEQLVKEVAAWRERYEDSQQEEAQYgamfQEQLM 836
Cdd:COG1196    360 LAEAEEALLEAEAELAEA----EEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEEL----EEALA 431

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  837 TLKEECEKARQELQEAKEKVAGIESHSELQISRQQNELAELhANLARALQQVQEKEVRAQKLADDLSTLQEKMAATSKEV 916
Cdd:COG1196    432 ELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEA-ALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGV 510

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  917 ARLETLVRKAGEQQETASRELVKEPARAGDRQPEwLEEQQGRQFCSTQAALQAMEREAEQMGNELERLRAALMESQGQQQ 996
Cdd:COG1196    511 KAALLLAGLRGLAGAVAVLIGVEAAYEAALEAAL-AAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALA 589

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  997 EERGQQEREVARLTQERGRAQADLALEKAARAELEMRLQNALNEQRVEFATLQEALAHALTEKEGKDQELAKLRGLEAAQ 1076
Cdd:COG1196    590 AALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRE 669

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1077 IKELEELRQTVKQLKEQLAKKEKEHASGSGAQSEAAGRteptgpKLEALRAEVSKLEQQCQKQQEQADSLERSLEAERAS 1156
Cdd:COG1196    670 LLAALLEAEAELEELAERLAEEELELEEALLAEEEEER------ELAEAEEERLEEELEEEALEEQLEAEREELLEELLE 743

                          570       580       590
                   ....*....|....*....|....*....|....*...
gi 1370459521 1157 RAERDSALETLQGQLEEKAQELghsQSALASAQRELAA 1194
Cdd:COG1196    744 EEELLEEEALEELPEPPDLEEL---ERELERLEREIEA 778
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1023-1656 1.64e-22

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 105.79  E-value: 1.64e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1023 EKAARA-ELEMRLQNALNEQRV-EFATLQEALAHALTEKEGKDQELAKLRGLEAAQIKELEELRQTVKQLKEQL-AKKEK 1099
Cdd:COG1196    210 EKAERYrELKEELKELEAELLLlKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELeEAQAE 289

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1100 EHASGSgaqseaagrteptgpKLEALRAEVSKLEQQCQKQQEQADSLERSLEAERASRAERDSALETLQGQLEEKAQELG 1179
Cdd:COG1196    290 EYELLA---------------ELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELE 354

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1180 HSQSALASAQRELAAFRTKVQDHSKAEDEWKAQVARGRQEAERKNSLISSLEEEVSILNRQVLEKEGESKELKrlvmAES 1259
Cdd:COG1196    355 EAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELE----EAL 430

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1260 EKSQKLEERLRLLQAETASNSARAAERSSALREEVQSLREEAEKQRVASENLRQELTSQAERAEELGQELKawqekffqk 1339
Cdd:COG1196    431 AELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEA--------- 501

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1340 eqalstlQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKRHREELEQSkqAAGGLRAELLRAQRELGELIPLRQKVAEQ 1419
Cdd:COG1196    502 -------DYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAA--LAAALQNIVVEDDEVAAAAIEYLKAAKAG 572

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1420 ERTAQQLRAEKASYAEQlsmlkkahgllAEENRGLGERANLGRQFLEVELDqAREKYVQELAAVRADAETRLAEVQREAQ 1499
Cdd:COG1196    573 RATFLPLDKIRARAALA-----------AALARGAIGAAVDLVASDLREAD-ARYYVLGDTLLGRTLVAARLEAALRRAV 640

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1500 STARELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVEQLEvfqrEQTKQVEELSKKLADSDQASKVQQQKLKAVQAQG 1579
Cdd:COG1196    641 TLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELE----ELAERLAEEELELEEALLAEEEEERELAEAEEER 716

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1370459521 1580 GESQQEAQRLQAQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAkkqqnqelqeqlrSLEQLQKENKELRAEAERLG 1656
Cdd:COG1196    717 LEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPP-------------DLEELERELERLEREIEALG 780
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 215-774 1.71e-22

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 105.79  E-value: 1.71e-22
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  215 QMRRLKKQLADERSNRDELELELAENRKLLTEKDAQIAMMQQRIDRLALlnekqaasplepkELEELRDKNESLTMRLHE 294
Cdd:COG1196    233 KLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELEL-------------ELEEAQAEEYELLAELAR 299

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  295 TLKQCQDLKTEKSQMDRKINQLSEEngdlsfkLREFASHLQQLQDALNELTEEHSKATQEWLEKQAQLEKELSAALQDKK 374
Cdd:COG1196    300 LEQDIARLEERRRELEERLEELEEE-------LAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEA 372

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  375 CLEEKNEILQGKLSQLEEHLSQLQDnppqekgevlgDVLQLETLKQEAATLAANNTQLQARVEMLETERGQQEAKLLAER 454
Cdd:COG1196    373 ELAEAEEELEELAEELLEALRAAAE-----------LAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEE 441

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  455 GHFEEEKQQLSSLITDLQSSISNLSQAKEELEQAsQAHGARLTAQVASLTSELTTLNATIQQQDQELAGLKQQAKEKQAQ 534
Cdd:COG1196    442 EALEEAAEEEAELEEEEEALLELLAELLEEAALL-EAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLR 520

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  535 -------------LAQTLQQQEQASQGLRHQVEQLSSSLKQKEQQLKEvAEKQEATRQDHAQQLATAAEEREASLRERDA 601
Cdd:COG1196    521 glagavavligveAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKA-AKAGRATFLPLDKIRARAALAAALARGAIGA 599

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  602 ALKQLEALEKEKAAKLEILQQQLQVANEARDSAQTSVTQAQREKAELSRKVEELQACVETARQEQHEAQAQVAELELQLR 681
Cdd:COG1196    600 AVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEA 679

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  682 SEQQKATEKERVAQEKDQLQEQLQALKESLKVTKGSLEEEKRRAADALEEQQRCISELKAETRSLVEQHKRERKELEEER 761
Cdd:COG1196    680 ELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEP 759

                          570
                   ....*....|...
gi 1370459521  762 AGRKGLEARLQQL 774
Cdd:COG1196    760 PDLEELERELERL 772
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 964-1541 6.58e-21

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 100.78  E-value: 6.58e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  964 QAALQAMEREAEQMGNELERLRAALmesqGQQQEERGQQEREVARLTQERGRAQADLALEKAARAELEM---RLQNALNE 1040
Cdd:COG1196    238 EAELEELEAELEELEAELEELEAEL----AELEAELEELRLELEELELELEEAQAEEYELLAELARLEQdiaRLEERRRE 313

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1041 QRVEFATLQEALAHALTEKEGKDQELAKLRGLEAAQIKELEELRQTVKQLKEQLAKKEKEHASGSGAQSEAAGRteptgp 1120
Cdd:COG1196    314 LEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEE------ 387

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1121 KLEALRAEVSKLEQQCQKQQEQADSLERSLEAERAsRAERDSALETLQGQLEEKAQELGHSQSALASAQRELAAFRTKVQ 1200
Cdd:COG1196    388 LLEALRAAAELAAQLEELEEAEEALLERLERLEEE-LEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLA 466

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1201 DHSKAEDEWKAQVARGRQEAERKNSLISSLEEevsiLNRQVLEKEGESKELKRLVMAESEKSQKLEERLRLLQAETASNS 1280
Cdd:COG1196    467 ELLEEAALLEAALAELLEELAEAAARLLLLLE----AEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEA 542

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1281 ARAAERSSALREEVQSLREEAE--KQRVASENLRQELTSQAERAEELGQELKAWQEKFF-------QKEQALSTLQLEHT 1351
Cdd:COG1196    543 ALAAALQNIVVEDDEVAAAAIEylKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVdlvasdlREADARYYVLGDTL 622

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1352 STQALVSELLPAKHLCQQLQAEQAAAEKRHREELEQSKQAAGGLRAELLRAQRELGELIPLRQKVAEQERTAQQLRAEKA 1431
Cdd:COG1196    623 LGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAE 702

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1432 SYAEQLSMLKKAHGLLAEENRGLGERANLGRQFLEVELDQAREKYVQELAAVRADAETRLAEVQREAQSTARELEVMtak 1511
Cdd:COG1196    703 EEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEAL--- 779

                          570       580       590
                   ....*....|....*....|....*....|.
gi 1370459521 1512 yeGA-KVKVLEERQRFQEERQKLTAQVEQLE 1541
Cdd:COG1196    780 --GPvNLLAIEEYEELEERYDFLSEQREDLE 808
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 845-1347 1.06e-20

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 100.01  E-value: 1.06e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  845 ARQELQEAKEKVAGIESHSELQISRQQNELAELHANLARALQQVQEKEVRAQKLADDLSTLQEKMAATSKEVARLETLVR 924
Cdd:COG1196    233 KLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRR 312

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  925 KAGEQQETASRELVKEPARAGDRQPEwLEEQQGRQfcstqAALQAMEREAEQMGNELERLRAALMESQGQQQEERGQQER 1004
Cdd:COG1196    313 ELEERLEELEEELAELEEELEELEEE-LEELEEEL-----EEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAE 386

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1005 EVARLTQER----------GRAQADLALEKAARAELEMRLQNALNEQRVEFATLQEALAHALTEKEGKDQELAKLRGLEA 1074
Cdd:COG1196    387 ELLEALRAAaelaaqleelEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLA 466

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1075 AQIKELEELRQTVKQLKEQLAKKEKEHASGSGAQSEAAGRTEPTGPKLEALR------------------------AEVS 1130
Cdd:COG1196    467 ELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGlrglagavavligveaayeaaleaALAA 546

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1131 KLEQQCQKQQEQADSLERSLEAERASRAERDSALETLQGQLEEKAQELGHSQSA---LASAQRELAAFRTKVQDHSKAED 1207
Cdd:COG1196    547 ALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAvdlVASDLREADARYYVLGDTLLGRT 626

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1208 EWKAQVARGRQEAERKNSLISSLEEEVSILNRQVLEKEGESKELKRLVMAESEKSQKLEERLRLLQAETASNSARAAERS 1287
Cdd:COG1196    627 LVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEE 706

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1288 SALREEVQSLREEAEKQRVASENLRQELTSQAERAEELGQELKAWQEKFFQKEQALSTLQ 1347
Cdd:COG1196    707 RELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELE 766
PTZ00121 PTZ00121
MAEBL; Provisional
 595-1328 1.80e-20

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 99.83  E-value: 1.80e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  595 SLRERDAALKQLEALEKEKAAKLEILQQQLQVANEARDSAQTSVTQAQR-----EKAELSRKVEELQACVETARQEQHEA 669
Cdd:PTZ00121  1068 QDEGLKPSYKDFDFDAKEDNRADEATEEAFGKAEEAKKTETGKAEEARKaeeakKKAEDARKAEEARKAEDARKAEEARK 1147

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  670 QAQVAELELQLRSEQQKATEKERVAQEKDQLQEQLQALkESLKVTKGSLEEEKRRAadalEEQQRCISELKAETRSLVEQ 749
Cdd:PTZ00121  1148 AEDAKRVEIARKAEDARKAEEARKAEDAKKAEAARKAE-EVRKAEELRKAEDARKA----EAARKAEEERKAEEARKAED 1222

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  750 HKRERKELEEERAGRKGLEARLQQLGEAHQAETEVLRRELAEAMAAQHTAESECEQLVKEVaawRERYEDSQQEEAQYGa 829
Cdd:PTZ00121  1223 AKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADEL---KKAEEKKKADEAKKA- 1298

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  830 mfqeqlmtlkEECEKARQELQEAKEKVAGIESHSELQISRQQNELAELHANLARALQQVQEKEvrAQKLADDLSTLQEKM 909
Cdd:PTZ00121  1299 ----------EEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAE--AEAAADEAEAAEEKA 1366

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  910 AA----TSKEVARLETLVRKAGEQQETasrELVKEPARAGDRQPEWLEEQQGRQFCSTQAALQAME-REAEQMGNELERL 984
Cdd:PTZ00121  1367 EAaekkKEEAKKKADAAKKKAEEKKKA---DEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEkKKADEAKKKAEEA 1443

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  985 RAAlmesqgqqqeergqqerevarlTQERGRAQADLALEKAARAELEMRLQNALNEQRVEFATLQEALAHAlTEKEGKDQ 1064
Cdd:PTZ00121  1444 KKA----------------------DEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKA-EEAKKKAD 1500

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1065 ELAKlrglEAAQIKELEELRQTVKQLKEQLAKKEKEHASGSGAQSEAAGRTEPTGPKLEALRA--EVSKLEQQCQKQQEQ 1142
Cdd:PTZ00121  1501 EAKK----AAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKaeEKKKAEEAKKAEEDK 1576

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1143 ADSLERSLEAERASRAERDSALETLQGQLEEKAQELGHSQSAlasaqrelaafRTKVQDHSKAEDEWKAQVARGRQEAE- 1221
Cdd:PTZ00121  1577 NMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEA-----------KIKAEELKKAEEEKKKVEQLKKKEAEe 1645

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1222 -RKNSLISSLEEEVSILNRQVLEKEGESKELKRLVMAESEKSQKLEERLRlLQAETASNSARAAERSSALREEVQSLREE 1300
Cdd:PTZ00121  1646 kKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALK-KEAEEAKKAEELKKKEAEEKKKAEELKKA 1724

                          730       740
                   ....*....|....*....|....*...
gi 1370459521 1301 AEKQRVASENLRQELTSQAERAEELGQE 1328
Cdd:PTZ00121  1725 EEENKIKAEEAKKEAEEDKKKAEEAKKD 1752
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 525-1365 3.94e-20

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 98.22  E-value: 3.94e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  525 KQQAKEKQAQLAQTLQQQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEATRQDHAQQLATAAEEREASLRERDAALK 604
Cdd:TIGR02169  172 KEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAERYQALLKEKREYEGYELLKEKEALERQKEAIERQLASLEE 251

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  605 QLEALEK---EKAAKLEILQQQL-QVANEARDSAQTSVTQAQREKAELSRKVEELQACVETARQEQHEAQAQVAELELQL 680
Cdd:TIGR02169  252 ELEKLTEeisELEKRLEEIEQLLeELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEI 331

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  681 RSEQQKATEKER----VAQEKDQLQEQLQALKESLKVTKGSLEEEKRRAA----------DALEEQQRCISELKAETRSL 746
Cdd:TIGR02169  332 DKLLAEIEELEReieeERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAetrdelkdyrEKLEKLKREINELKRELDRL 411

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  747 VEQHKRERKELEEERAGRKGLEARLQQLgeahQAETEVLRRELAEamaaqhtAESECEQLVKEVAAWRERYEDSQQEEAQ 826
Cdd:TIGR02169  412 QEELQRLSEELADLNAAIAGIEAKINEL----EEEKEDKALEIKK-------QEWKLEQLAADLSKYEQELYDLKEEYDR 480

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  827 YgamfQEQLMTLKEECEKARQELQEAKEKVAGIESHSELQISRQQNELAelhanLARALQQVQEK-----EVRAQKLADD 901
Cdd:TIGR02169  481 V----EKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVHG-----TVAQLGSVGERyataiEVAAGNRLNN 551

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  902 LSTLQEKMAATSKEVARletlVRKAGE------QQETASRELVKEPARAG---------DRQPEWleEQQGRQFCSTQAA 966
Cdd:TIGR02169  552 VVVEDDAVAKEAIELLK----RRKAGRatflplNKMRDERRDLSILSEDGvigfavdlvEFDPKY--EPAFKYVFGDTLV 625

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  967 LQAMEREAEQMGN-ELERLRAALMESQGQQQEERGQQEREVARLTQERGRAQADLALEKAARAELEmRLQNALNEQRVEF 1045
Cdd:TIGR02169  626 VEDIEAARRLMGKyRMVTLEGELFEKSGAMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELS-SLQSELRRIENRL 704

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1046 ATLQEALAHALTEKEGKDQELAKLRGLEAAQIKELEELRQTVKQLKEQLAKKEKEhasgsgaQSEAAGRTEPTGPKLEAL 1125
Cdd:TIGR02169  705 DELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSE-------LKELEARIEELEEDLHKL 777

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1126 RAEVSKLEQQCQKQQEqaDSLERSLEAERASRAERDSALETLQGQLEEKAQELGHSQSALASAQRELAAFRTKVQDHSKA 1205
Cdd:TIGR02169  778 EEALNDLEARLSHSRI--PEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKE 855

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1206 EDEWKAQVARGRQEAERKNSLISSLEEEVSILNRQVLEKEGESKELKRLVMAESEKSQKLEERLRLLQAETASNSARAAE 1285
Cdd:TIGR02169  856 IENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSE 935

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1286 RSSALREEVQSLREEAEKQRVASEnlRQELTSQAERAEELG----QELKAWQEKFFQKEQALSTLQLEHTSTQALVSELL 1361
Cdd:TIGR02169  936 IEDPKGEDEEIPEEELSLEDVQAE--LQRVEEEIRALEPVNmlaiQEYEEVLKRLDELKEKRAKLEEERKAILERIEEYE 1013


                   ....
gi 1370459521 1362 PAKH 1365
Cdd:TIGR02169 1014 KKKR 1017
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1015-1731 6.70e-20

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 97.43  E-value: 6.70e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1015 RAQADLALEKAARAELEMRLQN--ALNEQRVEFATLQEALAHA-----LTEKEGKDQELAKLRGLEAAQIKELEELRQTV 1087
Cdd:TIGR02168  183 RTRENLDRLEDILNELERQLKSleRQAEKAERYKELKAELRELelallVLRLEELREELEELQEELKEAEEELEELTAEL 262

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1088 KQLKEQLAKKEKEHASGSGAQSEAAGRteptgpkLEALRAEVSKLEQQCQKQQEQADSLERSLEAERASRAERDSALETL 1167
Cdd:TIGR02168  263 QELEEKLEELRLEVSELEEEIEELQKE-------LYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDEL 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1168 QGQLEEKAQELGHSQSALASAQRELAAFRTKVQDHSKAEDEWkaqvargRQEAERKNSLISSLEEEVSILNRQVLEKEGE 1247
Cdd:TIGR02168  336 AEELAELEEKLEELKEELESLEAELEELEAELEELESRLEEL-------EEQLETLRSKVAQLELQIASLNNEIERLEAR 408

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1248 SKELK-RLVMAESEKSQKLEERLRLLQAETASNSARAAERSSALREEVQSLREEAEKQRVASENLRQELTSQAERAEELG 1326
Cdd:TIGR02168  409 LERLEdRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQ 488

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1327 QELKAWQ------EKFFQKEQALSTLQLEHTSTQALVSELLPAKH---------LCQQLQAEQAAAEKRHREELEQSKQA 1391
Cdd:TIGR02168  489 ARLDSLErlqenlEGFSEGVKALLKNQSGLSGILGVLSELISVDEgyeaaieaaLGGRLQAVVVENLNAAKKAIAFLKQN 568

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1392 AGGLRAELLRAQRELGELIPLRQKVAEQERTAQQLRAEKASYAEQLSM--------------LKKAHGLLAEENRGL--- 1454
Cdd:TIGR02168  569 ELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKalsyllggvlvvddLDNALELAKKLRPGYriv 648

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1455 ----------------GERANLGRQFLEVELDQAREKyVQELAAVRADAETRLAEVQREAQSTARELEVMTAKYEGAKVK 1518
Cdd:TIGR02168  649 tldgdlvrpggvitggSAKTNSSILERRREIEELEEK-IEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQ 727

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1519 VLEER---QRFQEERQKLTAQVEQLEVFQREQTKQVEELSKKLADSDQASKVQQQKLKAVQAQGGESQQEAQRLQAQLNE 1595
Cdd:TIGR02168  728 ISALRkdlARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDE 807

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1596 LQAQLSQKEQAAEHYKLQMEKAKTHYDAKKqqnqelqeqlRSLEQLQKENKELRAEAERLGHELQQAGLKTKEAEQTCRH 1675
Cdd:TIGR02168  808 LRAELTLLNEEAANLRERLESLERRIAATE----------RRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEA 877

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1370459521 1676 LTAQVRSLEAQVAHADQQLRDLGKFQVATDALKSREPQAKPQLDLSIDSLDLSCEE 1731
Cdd:TIGR02168  878 LLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEG 933
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 831-1656 9.24e-20

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 97.05  E-value: 9.24e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  831 FQEQLMTLKEECEKARQELQEAKEKVAGIESHSE---LQISRQQNELAELHANLARALQQVQEKEVRAQKLaddlstlQE 907
Cdd:TIGR02168  237 LREELEELQEELKEAEEELEELTAELQELEEKLEelrLEVSELEEEIEELQKELYALANEISRLEQQKQIL-------RE 309

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  908 KMAATSKEVARLETLVRKAGEQQETASRELVKEPARAGDRQPEWLEEQQgrQFCSTQAALQAMEREAEQMGNELERLRAA 987
Cdd:TIGR02168  310 RLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEA--ELEELEAELEELESRLEELEEQLETLRSK 387

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  988 lmesqgqqqeergqqereVARLTQERGRAQADLALEKAARAELEMRLQNALNEQRVEFATLQEALAHAL-TEKEGKDQEL 1066
Cdd:TIGR02168  388 ------------------VAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELqAELEELEEEL 449

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1067 AKLRGLEAAQIKELEELRQTVKQLKEQLAKKEKEHASGSGAQSEAAGRTEptgpKLEALRAEVSKLEQQCQKQQEQADSL 1146
Cdd:TIGR02168  450 EELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQE----NLEGFSEGVKALLKNQSGLSGILGVL 525

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1147 ERSLEAERASRAERDSAL-ETLQGQLEEKAQELGHSQSALASAQRELAAFrtkvqdhsKAEDEWKAQVARGRQEAERKNs 1225
Cdd:TIGR02168  526 SELISVDEGYEAAIEAALgGRLQAVVVENLNAAKKAIAFLKQNELGRVTF--------LPLDSIKGTEIQGNDREILKN- 596

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1226 lissLEEEVSILNRQVLEKEGESKE----LKRLVMAES-----EKSQKLEERLR-------LLQAETASNSARAAERSSA 1289
Cdd:TIGR02168  597 ----IEGFLGVAKDLVKFDPKLRKAlsylLGGVLVVDDldnalELAKKLRPGYRivtldgdLVRPGGVITGGSAKTNSSI 672

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1290 LreevqslreeaeKQRVASENLRQELTSQAERAEELGQELKAWQEKFFQKEQALSTLQLEHTSTQALVSELlpakhlcQQ 1369
Cdd:TIGR02168  673 L------------ERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISAL-------RK 733

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1370 LQAEQAAAEKRHREELEQSKQAAGGLRAELLRAQRELGElipLRQKVAEQERTAQQLRAEKASYAEQLSMLKKAHGLLAE 1449
Cdd:TIGR02168  734 DLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEE---AEEELAEAEAEIEELEAQIEQLKEELKALREALDELRA 810

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1450 EnrglgeranlgrqfleveldqarekyVQELAAVRADAETRLAEVQREAQSTARELEVMTakyegakvkvlEERQRFQEE 1529
Cdd:TIGR02168  811 E--------------------------LTLLNEEAANLRERLESLERRIAATERRLEDLE-----------EQIEELSED 853

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1530 RQKLTAQVEQLEVFQREQTKQVEELSKKLADSDQASKVQQQKLKAVQAQGGESQQEAQRLQAQLNELQAQLSQ------- 1602
Cdd:TIGR02168  854 IESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQlelrleg 933

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1370459521 1603 --------KEQAAEHYKLQMEKAKTHYDAKKQqnqelqeqlrSLEQLQKENKELRAEAERLG 1656
Cdd:TIGR02168  934 levridnlQERLSEEYSLTLEEAEALENKIED----------DEEEARRRLKRLENKIKELG 985
PTZ00121 PTZ00121
MAEBL; Provisional
 517-1250 1.09e-19

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 97.13  E-value: 1.09e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  517 QDQELAGLKQQAKEKQAQLAQTLQQQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEATRQDHAQQLATAAEEREASL 596
Cdd:PTZ00121  1077 KDFDFDAKEDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAEDAKRVEI 1156

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  597 -RERDAALKQLEALEKEKAAKLEILQQQLQV--ANEARDSAQTSVTQAQReKAELSRKVEElqacVETARQEQHEAQAQV 673
Cdd:PTZ00121  1157 aRKAEDARKAEEARKAEDAKKAEAARKAEEVrkAEELRKAEDARKAEAAR-KAEEERKAEE----ARKAEDAKKAEAVKK 1231

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  674 AElELQLRSEQQKATEKERVAQEKDQLQEQLQAlkeslkvtkgslEEEKRRAADALEEQQRCISELKAETRSLVEQHKRE 753
Cdd:PTZ00121  1232 AE-EAKKDAEEAKKAEEERNNEEIRKFEEARMA------------HFARRQAAIKAEEARKADELKKAEEKKKADEAKKA 1298

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  754 RKELEEERAGRKGLEAR----LQQLGEAHQAETEVLRRELAEAMAAQHTAESECEQLVKEVAAWRERYE--DSQQEEAQY 827
Cdd:PTZ00121  1299 EEKKKADEAKKKAEEAKkadeAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEaaEKKKEEAKK 1378

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  828 GAmfqEQLMTLKEECEKARQELQEAKEKVAGIESHSELQISRQQNELAELHANLARALQQVQEKEVRAQKladdlstlQE 907
Cdd:PTZ00121  1379 KA---DAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKK--------AD 1447

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  908 KMAATSKEVARLETLVRKAGEQQETASRELVKEPARAGDRQPEWLEEQQGRQFCSTQAALQAME----REAEQMGNELER 983
Cdd:PTZ00121  1448 EAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKadeaKKAEEAKKADEA 1527

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  984 LRAALMESQGQQQEERGQQEREVARLTQERGRAQADLALEKAARAELE--MRLQNALNEQRVEFATLQEALAHALTEKEG 1061
Cdd:PTZ00121  1528 KKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDknMALRKAEEAKKAEEARIEEVMKLYEEEKKM 1607

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1062 KDQELAKLR--GLEAAQIKELEELRQTVKQLKEQLAKKEKEHASGSGAQSEAAGRTEPTGPKLEALRAEVSKLEQQCQKQ 1139
Cdd:PTZ00121  1608 KAEEAKKAEeaKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDE 1687

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1140 QEQADSLERslEAERASRAERdsaLETLQGQLEEKAQELghsqsalasaQRELAAFRTKVQDHSKAEDEWKAQVARGRQE 1219
Cdd:PTZ00121  1688 KKAAEALKK--EAEEAKKAEE---LKKKEAEEKKKAEEL----------KKAEEENKIKAEEAKKEAEEDKKKAEEAKKD 1752

                          730       740       750
                   ....*....|....*....|....*....|.
gi 1370459521 1220 AERKNSLISSLEEEVSILNRQVLEKEGESKE 1250
Cdd:PTZ00121  1753 EEEKKKIAHLKKEEEKKAEEIRKEKEAVIEE 1783
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 783-1596 3.07e-19

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 95.51  E-value: 3.07e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  783 EVLRRELAEAMAAQHTAESECEQLVKEVAAWRERYEDSQQEEAQygamfqeqlmtLKEECEKARQELQEAKEKVAGIESh 862
Cdd:TIGR02168  235 EELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSE-----------LEEEIEELQKELYALANEISRLEQ- 302

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  863 selQISRQQNELAELHANLARALQQVQEKEVRAQKLADDLSTLQEKMAATSKEVARLETLVRKAGEQQETASRelvkepa 942
Cdd:TIGR02168  303 ---QKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELES------- 372

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  943 RAGDRQPEWLEEqqgrqfcstQAALQAMEREAEQMGNELERLRAALmesqgqqqeerGQQEREVARLTQErgRAQADLAL 1022
Cdd:TIGR02168  373 RLEELEEQLETL---------RSKVAQLELQIASLNNEIERLEARL-----------ERLEDRRERLQQE--IEELLKKL 430

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1023 EKAARAELEMRlqnaLNEQRVEFATLQEALAHALTEKEGKDQELAKLRGLEAAQIKELEELRQTVKQLKEQLAKKEKEHA 1102
Cdd:TIGR02168  431 EEAELKELQAE----LEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSE 506

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1103 SGSGAQSEAAGRTEPTGPKLE--------------ALRAEVSKLEQQCQKQQEQADSLERSLEAERASRAERDSALETlq 1168
Cdd:TIGR02168  507 GVKALLKNQSGLSGILGVLSElisvdegyeaaieaALGGRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGT-- 584

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1169 gQLEEKAQELGHSQSALASAQRELAAFRTKVQdhsKAEDEWKAQV--------ARGRQEAERKNSLISSLEEEVsILNRQ 1240
Cdd:TIGR02168  585 -EIQGNDREILKNIEGFLGVAKDLVKFDPKLR---KALSYLLGGVlvvddldnALELAKKLRPGYRIVTLDGDL-VRPGG 659

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1241 VLEKEGESKELKRLvmAESEKSQKLEERLRLLQAETASNSARAAErssaLREEVQSLREEAEKQRVASENLRQELTSQAE 1320
Cdd:TIGR02168  660 VITGGSAKTNSSIL--ERRREIEELEEKIEELEEKIAELEKALAE----LRKELEELEEELEQLRKELEELSRQISALRK 733

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1321 RAEELGQELKAWQEKFFQKEQALSTLQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKRHREELEQSKQAAGGLRAELL 1400
Cdd:TIGR02168  734 DLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELT 813

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1401 RaqrelgelipLRQKVAEQERTAQQLRAEKASYAEQLSMLKKAhgllAEENRGLGERANLGRQFLEVELDQAREKyVQEL 1480
Cdd:TIGR02168  814 L----------LNEEAANLRERLESLERRIAATERRLEDLEEQ----IEELSEDIESLAAEIEELEELIEELESE-LEAL 878

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1481 AAVRADAETRLAEVQREAQSTARELEVMTAkyegakvKVLEERQRFQEERQKLTAQVEQLEVFQREQTKQVEELSKKLAD 1560
Cdd:TIGR02168  879 LNERASLEEALALLRSELEELSEELRELES-------KRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSL 951

                          810       820       830
                   ....*....|....*....|....*....|....*.
gi 1370459521 1561 SDQASKVQQQKLKAVQAqggESQQEAQRLQAQLNEL 1596
Cdd:TIGR02168  952 TLEEAEALENKIEDDEE---EARRRLKRLENKIKEL 984
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1144-1699 5.56e-19

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 94.23  E-value: 5.56e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1144 DSLERslEAERASRAErdsaleTLQGQLEEKAQELghSQSALASAQRELAAFRTKVQDHSKAEDEWKAQVARGRQEAERK 1223
Cdd:COG1196    203 EPLER--QAEKAERYR------ELKEELKELEAEL--LLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEEL 272

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1224 NSLISSLEEEVSILNRQVLEKEGESKELKRLVMAESEKSQKLEERLRLLQAETASNSARAAERSSALREEVQSLREEAEK 1303
Cdd:COG1196    273 RLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEE 352

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1304 QRVASENLRQELTSQAERAEELGQELKAWQEKFFQKEQALSTLQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKRHRE 1383
Cdd:COG1196    353 LEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAE 432

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1384 ELEQSKQAAGGLRAELLRAQRELGELIPLRQKVAEQERTA-------QQLRAEKASYAEQLSMLKKAHGLLAEENRGLGE 1456
Cdd:COG1196    433 LEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAalleaalAELLEELAEAAARLLLLLEAEADYEGFLEGVKA 512

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1457 RANLGRQF-LEVELDQAREKYVQELAAVRADAETRLAEVQREAQSTARE-----------------LEVMTAKYEGAKVK 1518
Cdd:COG1196    513 ALLLAGLRgLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAaieylkaakagratflpLDKIRARAALAAAL 592

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1519 VLEERQRF--------QEERQKLTAQVEQLEVFQREQTKQVEELSKKLADSDQASKVQQQKLKAVQAQGGESQQEAQRLQ 1590
Cdd:COG1196    593 ARGAIGAAvdlvasdlREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLA 672

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1591 AQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQELQEQLRSLEQLQKENKELRAEAERLGHELQQAGLKTKEAE 1670
Cdd:COG1196    673 ALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEA 752

                          570       580
                   ....*....|....*....|....*....
gi 1370459521 1671 QTCRHLTAQVRSLEAQVAHADQQLRDLGK 1699
Cdd:COG1196    753 LEELPEPPDLEELERELERLEREIEALGP 781
PTZ00121 PTZ00121
MAEBL; Provisional
 1008-1670 1.78e-18

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 93.28  E-value: 1.78e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1008 RLTQERGRAQADLALEKAARAELEMRLQNALNEQRVEFATLQEALAHALTEKEGKDQELAKlrglEAAQIKELEELRQTV 1087
Cdd:PTZ00121  1110 KAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAEDAKRVEIARKAEDARKAEEAR----KAEDAKKAEAARKAE 1185

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1088 KQLKEQLAKKEKEhasgsGAQSEAAGRTEPTGPKLEALRAEVSKLEQQCQKQQEQADSLERSLEAERASRAERDSALETL 1167
Cdd:PTZ00121  1186 EVRKAEELRKAED-----ARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEA 1260

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1168 QGQLEEKAQELGHSQSALASAQRELAAFRTKVQDHSKAEDEWKAQVARGRQEAERKNSLISSLEEEVSILNRQVLEKEGE 1247
Cdd:PTZ00121  1261 RMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEE 1340

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1248 SKELKRLVMAESEKSQKleerlrllQAETASNSARAAE-RSSALREEVQSLREEAEKQRVASENLR--QELTSQAERAEE 1324
Cdd:PTZ00121  1341 AKKAAEAAKAEAEAAAD--------EAEAAEEKAEAAEkKKEEAKKKADAAKKKAEEKKKADEAKKkaEEDKKKADELKK 1412

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1325 LGQELKAWQEKFFQKEQALSTLQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKRHREELEQSKQAAGGLRAELLRAQ- 1403
Cdd:PTZ00121  1413 AAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKa 1492

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1404 RELGELIPLRQKVAEQERTAQQLR-AEKASYAEQLSMLKKAHGllAEENRGLGERANLGRQFLEVELDQAREKYVQE--- 1479
Cdd:PTZ00121  1493 EEAKKKADEAKKAAEAKKKADEAKkAEEAKKADEAKKAEEAKK--ADEAKKAEEKKKADELKKAEELKKAEEKKKAEeak 1570

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1480 LAAVRADAETRLAEVQREAQStARELEVMTAKYEGAKVKVlEERQRFQEERQKlTAQVEQLEvfqrEQTKQVEELSKKLA 1559
Cdd:PTZ00121  1571 KAEEDKNMALRKAEEAKKAEE-ARIEEVMKLYEEEKKMKA-EEAKKAEEAKIK-AEELKKAE----EEKKKVEQLKKKEA 1643

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1560 DSDQASKVQQQKLKAVQAQGGESQQEAQRLQAQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKqqnqELQEQLRSLE 1639
Cdd:PTZ00121  1644 EEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKK----KEAEEKKKAE 1719

                          650       660       670
                   ....*....|....*....|....*....|.
gi 1370459521 1640 QLQKENKELRAEAERLGHELQQAGLKTKEAE 1670
Cdd:PTZ00121  1720 ELKKAEEENKIKAEEAKKEAEEDKKKAEEAK 1750
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 277-860 3.24e-18

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 91.92  E-value: 3.24e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  277 ELEELRDKNESLTMRLHETLKQCQDLKTEKSQMDRKINQLSEENGDLSFKLREFASHLQQLQDALNELTEEHSKAT---Q 353
Cdd:COG1196    233 KLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEerrR 312

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  354 EWLEKQAQLEKELSAALQDKKCLEEKNEILQGKLSQLEEHLSQLQdnppqekgevlgdvlqlETLKQEAATLAANNTQLQ 433
Cdd:COG1196    313 ELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAE-----------------AELAEAEEALLEAEAELA 375

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  434 ARVEMLETERgQQEAKLLAERGHFEEEKQQLSSLITDLQSSISNLSQAKEELEQASQAHGARLTAQVASLTSELTTLNAT 513
Cdd:COG1196    376 EAEEELEELA-EELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAEL 454

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  514 IQQQDQELAGLKQQAKEKQaqlaqtlqqqeqasqglrhQVEQLSSSLKQKEQQLKEVAEKQEATRQDHAQQLATAAEERE 593
Cdd:COG1196    455 EEEEEALLELLAELLEEAA-------------------LLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALL 515

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  594 ASLRERDAALKQLEALEKEKAAKLEILQQQLQVANEARDSAQTSVTQAQREKAELSRKVEELQACVETARQEQHEAQAQV 673
Cdd:COG1196    516 LAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARG 595

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  674 AELE--LQLRSEQQKATEKERVAQEKDQLQEQLQALKESLKVTKGSLEEEKRRAADALEEqqrcISELKAETRSLVEQHK 751
Cdd:COG1196    596 AIGAavDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEG----GSAGGSLTGGSRRELL 671

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  752 RERKELEEERAGRKGLEARLQQLGEAHQAETEVLRRELAEAMAAQHTAESECEQLVKEVAAWRERYEDSQQEEAQYGAMF 831
Cdd:COG1196    672 AALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEE 751

                          570       580
                   ....*....|....*....|....*....
gi 1370459521  832 QEQLMTLKEECEKARQELQEAKEKVAGIE 860
Cdd:COG1196    752 ALEELPEPPDLEELERELERLEREIEALG 780
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 906-1683 3.70e-17

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 88.58  E-value: 3.70e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  906 QEKMAATSKEVARLETLVRKAGEQQETASR--ELVKEPARAGDRQPEWLEEQQGRQFCSTQAALQAMEREAEQMGNELER 983
Cdd:TIGR02168  178 ERKLERTRENLDRLEDILNELERQLKSLERqaEKAERYKELKAELRELELALLVLRLEELREELEELQEELKEAEEELEE 257

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  984 LRAALMESQGQQQEERGQqereVARLTQERGRAQADLALEKAARAELEMRLQnalnEQRVEFATLQEALAHALTEKEGKD 1063
Cdd:TIGR02168  258 LTAELQELEEKLEELRLE----VSELEEEIEELQKELYALANEISRLEQQKQ----ILRERLANLERQLEELEAQLEELE 329

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1064 QELAKLRGLEAAQIKELEELRQTVKQLKEQLAKKEKEhasgsgaQSEAAGRTEPTGPKLEALRAEVSKLEQQCQKQQEQA 1143
Cdd:TIGR02168  330 SKLDELAEELAELEEKLEELKEELESLEAELEELEAE-------LEELESRLEELEEQLETLRSKVAQLELQIASLNNEI 402

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1144 DSLERSLEAERASRAERDSALETLQGQLEEkaQELGHSQSALASAQRELAAFRTKVQDHSKAEDEWKAQVARGRQEAERK 1223
Cdd:TIGR02168  403 ERLEARLERLEDRRERLQQEIEELLKKLEE--AELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAA 480

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1224 NSLISSLEEEVSILNRQVLEKEGESKELKRLVMAESEKSQKLEERLRLLQAETASNSARAAerssALREEVQSL-REEAE 1302
Cdd:TIGR02168  481 ERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGYEAAIEA----ALGGRLQAVvVENLN 556

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1303 KQRVASENLRQ---------ELTSQAERA-EELGQELKAWQEKFFQkeqALSTLQLEHTSTQALVSELLPAKHLCQQLQA 1372
Cdd:TIGR02168  557 AAKKAIAFLKQnelgrvtflPLDSIKGTEiQGNDREILKNIEGFLG---VAKDLVKFDPKLRKALSYLLGGVLVVDDLDN 633

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1373 EQAAAEKRHREELEQSKQ----------AAGGLRAELLRAQRElGELIPLRQKVAEQERTAQQLRAEKASYAEQLSMLKK 1442
Cdd:TIGR02168  634 ALELAKKLRPGYRIVTLDgdlvrpggviTGGSAKTNSSILERR-REIEELEEKIEELEEKIAELEKALAELRKELEELEE 712

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1443 AHGLLAEENRGLGERANLGRQFLEVEldqarEKYVQELAAVRADAETRLAEVQREAQSTARELEvmtaKYEGAKVKVLEE 1522
Cdd:TIGR02168  713 ELEQLRKELEELSRQISALRKDLARL-----EAEVEQLEERIAQLSKELTELEAEIEELEERLE----EAEEELAEAEAE 783

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1523 RQRFQEERQKLTAQVEQLEVFQREQTKQVEELSKKLADSDQASKVQQQKLKAVQAQGGESQQEAQRLQAQLNELQAQLSQ 1602
Cdd:TIGR02168  784 IEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEE 863

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1603 KEQAAEHYKLQMEKAKTHYDAK----KQQNQELQEQLRSLEQLQKENKELRAEAERLGHELQQAGLKTKEAEQTCRHLTA 1678
Cdd:TIGR02168  864 LEELIEELESELEALLNERASLeealALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQE 943


                   ....*
gi 1370459521 1679 QVRSL 1683
Cdd:TIGR02168  944 RLSEE 948
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 833-1663 8.85e-17

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 87.42  E-value: 8.85e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  833 EQLMTLKEECEKARQELQ--EAKEKVAGIEShSELQISRQQNELAELHANLARALQQVQEKEVRAQKLADDLSTLQEKMA 910
Cdd:TIGR02168  213 ERYKELKAELRELELALLvlRLEELREELEE-LQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELY 291

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  911 ATSKEVARLETLVRKAGEQQEtasrELVKEPARAGDRQPEWLE--EQQGRQFCSTQAALQAMEREAEQMGNELERLRAAL 988
Cdd:TIGR02168  292 ALANEISRLEQQKQILRERLA----NLERQLEELEAQLEELESklDELAEELAELEEKLEELKEELESLEAELEELEAEL 367

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  989 MESQGQQQEERGQ---QEREVARLTQERGRAQADLALEKAARAELEMRLQNALNEQRVEFATLQEALAHAL-TEKEGKDQ 1064
Cdd:TIGR02168  368 EELESRLEELEEQletLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELqAELEELEE 447

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1065 ELAKLRGLEAAQIKELEELRQTVKQLKEQLAKKEKEHASGSGAQSEAAGRTEptgpKLEALRAEVSKLEQQCQKQQEQAD 1144
Cdd:TIGR02168  448 ELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQE----NLEGFSEGVKALLKNQSGLSGILG 523

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1145 SLERSLEAERASRAERDSAL-ETLQGQLEEKAQELGHSQSALASAQRELAAFrtkvqdhsKAEDEWKAQVARGRQEAERK 1223
Cdd:TIGR02168  524 VLSELISVDEGYEAAIEAALgGRLQAVVVENLNAAKKAIAFLKQNELGRVTF--------LPLDSIKGTEIQGNDREILK 595

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1224 NSlisslEEEVSILNRQVLEKEGESKE----LKRLVMAES-----EKSQKLEERLR-------LLQAETASNSARAAERS 1287
Cdd:TIGR02168  596 NI-----EGFLGVAKDLVKFDPKLRKAlsylLGGVLVVDDldnalELAKKLRPGYRivtldgdLVRPGGVITGGSAKTNS 670

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1288 SALreevqslreeaeKQRVASENLRQELTSQAERAEELGQELKAWQEKFFQKEQALSTLQLEHTSTQALVSELlpakhlc 1367
Cdd:TIGR02168  671 SIL------------ERRREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISAL------- 731

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1368 QQLQAEQAAAEKRHREELEQSKQAAGGLRAELLRAQRELGELiplRQKVAEQERTAQQLRAEKASYAEQLSMLKKAHGLL 1447
Cdd:TIGR02168  732 RKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEA---EEELAEAEAEIEELEAQIEQLKEELKALREALDEL 808

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1448 AEEnrglgeranlgrqfleveldqarekyVQELAAVRADAETRLAEVQREAQSTARELEVMTakyegakvkvlEERQRFQ 1527
Cdd:TIGR02168  809 RAE--------------------------LTLLNEEAANLRERLESLERRIAATERRLEDLE-----------EQIEELS 851

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1528 EERQKLTAQVEQLEVFQREQTKQVEELSKKLADSDQASKVQQQKLKAVQAQGGESQQEAQRLQAQLNELQAQLSQkeqaa 1607
Cdd:TIGR02168  852 EDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQ----- 926

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1370459521 1608 ehYKLQMEKAKthydakkQQNQELQEQLRSLEQLQKEN------------KELRAEAERLGHELQQAG 1663
Cdd:TIGR02168  927 --LELRLEGLE-------VRIDNLQERLSEEYSLTLEEaealenkieddeEEARRRLKRLENKIKELG 985
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 434-1302 2.10e-16

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 85.89  E-value: 2.10e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  434 ARVEMLETERGQQEAKLLAERGHFEEEKQQLSSLITDLQSSISNLSQAKEELEQASQAHGARLTAQVASLTSELTTLNAT 513
Cdd:TIGR02169  187 ERLDLIIDEKRQQLERLRREREKAERYQALLKEKREYEGYELLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKR 266

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  514 IQQQDQELAGLKQQAKEKQAQLAQTLQQQEQASQGlrhQVEQLSSSLKQKEQQLKEVAEKQEATRQDHAQQLATAaEERE 593
Cdd:TIGR02169  267 LEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEA---EIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEI-EELE 342

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  594 ASLRERDAALKQLEALEKEKAAKLEILQQQLQVANEARDSAQTSVTQAQREKAELSRKVEELQACVETARQEQHEAQAQV 673
Cdd:TIGR02169  343 REIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEEL 422

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  674 AELELQLRSEQQKATEKERVAQEKD-------QLQEQLQALKESLKVTKGSLEEEKRRAADALEEQQRCISELKAETRSL 746
Cdd:TIGR02169  423 ADLNAAIAGIEAKINELEEEKEDKAleikkqeWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARAS 502

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  747 VEQHKRERKELEEERAGRKGLEARLQQLG---EAHQAETEV-LRRELAEAMAAQHTAESECEQLVKEVAAWR-------- 814
Cdd:TIGR02169  503 EERVRGGRAVEEVLKASIQGVHGTVAQLGsvgERYATAIEVaAGNRLNNVVVEDDAVAKEAIELLKRRKAGRatflplnk 582

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  815 ----ERYEDSQQEEAQYGamFQEQLMTLKEECEKARQELQEAKEKVAGIESHSELQIsrqqnelaelhanlaralqqvqe 890
Cdd:TIGR02169  583 mrdeRRDLSILSEDGVIG--FAVDLVEFDPKYEPAFKYVFGDTLVVEDIEAARRLMG----------------------- 637

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  891 kEVRAQKLADDLSTLQEKMAATSKEVARLETLVRKAGEQQETASRELvkepaRAGDRQPEWLEEQQGRQFCSTQAALQAM 970
Cdd:TIGR02169  638 -KYRMVTLEGELFEKSGAMTGGSRAPRGGILFSRSEPAELQRLRERL-----EGLKRELSSLQSELRRIENRLDELSQEL 711

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  971 eREAEQMGNELERlraalmesqgqqqeergqqerevarltqERGRAQADLALEKAARAELEMRLQnalnEQRVEFATLQE 1050
Cdd:TIGR02169  712 -SDASRKIGEIEK----------------------------EIEQLEQEEEKLKERLEELEEDLS----SLEQEIENVKS 758

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1051 ALAHALTEKEGKDQELAKLRgleaAQIKELE--ELRQTVKQLKEQLAKKEKEHASGSGAQSEAAGRTEPTGPKLEALRAE 1128
Cdd:TIGR02169  759 ELKELEARIEELEEDLHKLE----EALNDLEarLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKE 834

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1129 VSKLEQQCQKQQEQADSLERSLEAERASRAERDSALETLQGQLEEKAQELGHSQSALASAQRELAAFRTKVQdhskaedE 1208
Cdd:TIGR02169  835 IQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIE-------E 907

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1209 WKAQVARGRQEAERKNSLISSLEEEVSILNRQVLEKEGESKELKRLVMAESEKsQKLEERLRLLqaETASNSA-----RA 1283
Cdd:TIGR02169  908 LEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELSLEDVQAEL-QRVEEEIRAL--EPVNMLAiqeyeEV 984

                          890
                   ....*....|....*....
gi 1370459521 1284 AERSSALREEVQSLREEAE 1302
Cdd:TIGR02169  985 LKRLDELKEKRAKLEEERK 1003
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 553-1331 4.31e-16

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 85.12  E-value: 4.31e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  553 VEQLSSSLKQKEQQLKEVAEKQEATR---QDHAQQLATAAEEREASLRERDAALKQLEALEKEKAAKLEILQQQLQvane 629
Cdd:TIGR02169  165 VAEFDRKKEKALEELEEVEENIERLDliiDEKRQQLERLRREREKAERYQALLKEKREYEGYELLKEKEALERQKE---- 240

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  630 ardsaqtsvtQAQREKAELSRKVEELQACVETARQEQHEAQAQVAELELQLRseqqKATEKERVaqekdQLQEQLQALKE 709
Cdd:TIGR02169  241 ----------AIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIK----DLGEEEQL-----RVKEKIGELEA 301

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  710 SLKVTKGSLEEEKRRAADALEEQQrcisELKAETRSLVEQHKRERKELEEERAGRKGLEARLQQLgeahQAETEVLRREL 789
Cdd:TIGR02169  302 EIASLERSIAEKERELEDAEERLA----KLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAEL----KEELEDLRAEL 373

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  790 AEAMAAQHTAESECEQLVKEVAAWRERYEDSQQEEAQygamFQEQLMTLKEECEKARQELQEAKEKVAGIESHSE---LQ 866
Cdd:TIGR02169  374 EEVDKEFAETRDELKDYREKLEKLKREINELKRELDR----LQEELQRLSEELADLNAAIAGIEAKINELEEEKEdkaLE 449

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  867 ISRQQNELAELHANLARALQQVQEKEVRAQKLADDLSTLQEKMAA--TSKEVARLETLVRKAGEQQETASRE----LVKE 940
Cdd:TIGR02169  450 IKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEaeAQARASEERVRGGRAVEEVLKASIQgvhgTVAQ 529

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  941 PARAGDRQPEWLEEQQGRQFcstQAALQAMEREAEQMGNELERLRAALMESQGQQQEERGQQEREVARLTQERGRAQADL 1020
Cdd:TIGR02169  530 LGSVGERYATAIEVAAGNRL---NNVVVEDDAVAKEAIELLKRRKAGRATFLPLNKMRDERRDLSILSEDGVIGFAVDLV 606

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1021 ALEKAARAELEMRLQNALNEQRVEFATLQE------ALAHALTEKEG---------------KDQELAKLRGLeAAQIKE 1079
Cdd:TIGR02169  607 EFDPKYEPAFKYVFGDTLVVEDIEAARRLMgkyrmvTLEGELFEKSGamtggsraprggilfSRSEPAELQRL-RERLEG 685

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1080 LEELRQTvkqLKEQLAKKEKEHASGSGAQSEAAGRTEPTGPKLEALRAEVSKLEQQCQKQQEQADSLERSLEAERASrae 1159
Cdd:TIGR02169  686 LKRELSS---LQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSE--- 759

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1160 rdsaLETLQGQLEEKAQELGHSQSALASAQRELA--AFRTKVQDHSKAEDEWKAQVARGR---QEAERKNSLISSLEEEV 1234
Cdd:TIGR02169  760 ----LKELEARIEELEEDLHKLEEALNDLEARLShsRIPEIQAELSKLEEEVSRIEARLReieQKLNRLTLEKEYLEKEI 835

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1235 SILNRQVLEKEGESKELKRLVMAESEKSQKLEERLRLLQAETASNSARaaerssalREEVQSLREEAEKQRVASENLRQE 1314
Cdd:TIGR02169  836 QELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESR--------LGDLKKERDELEAQLRELERKIEE 907

                          810
                   ....*....|....*..
gi 1370459521 1315 LTSQAERAEELGQELKA 1331
Cdd:TIGR02169  908 LEAQIEKKRKRLSELKA 924
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 782-1656 9.38e-16

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 83.96  E-value: 9.38e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  782 TEVLRRELAEAMAAQHTAESECEQLVKEVAAWRERYEDSQQEEAQYGamfqEQLMTLKEECEKAR--QELQEAKEKVAGI 859
Cdd:TIGR02169  151 SPVERRKIIDEIAGVAEFDRKKEKALEELEEVEENIERLDLIIDEKR----QQLERLRREREKAEryQALLKEKREYEGY 226

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  860 ESHSEL-----QISRQQNELAELHANLARALQQVQEKEVRAQKLADDLSTLQEK-MAATSKEVARLETLVRKAGEQQETA 933
Cdd:TIGR02169  227 ELLKEKealerQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKiKDLGEEEQLRVKEKIGELEAEIASL 306

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  934 SRELvkepaRAGDRQPEWLEEQQGRqfcsTQAALQAMEREAEQMGNELERLRAALMESQGQQQEERGQQEREVARLTQER 1013
Cdd:TIGR02169  307 ERSI-----AEKERELEDAEERLAK----LEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVD 377

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1014 GRAQADLALEKAARAELEMrLQNALNEQRVEFATLQEalahaltEKEGKDQELAKLRGLEAAQIKELEELRQTVKQLKEQ 1093
Cdd:TIGR02169  378 KEFAETRDELKDYREKLEK-LKREINELKRELDRLQE-------ELQRLSEELADLNAAIAGIEAKINELEEEKEDKALE 449

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1094 LAKKEKEHASGSGAQSEAAGRTEPTGPKLEALRAEVSKLEQQCQKQQEQADSLERSLEAERASRAERDSALETLQGQLEE 1173
Cdd:TIGR02169  450 IKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQ 529

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1174 KAQELGHSQSALASAQ-RELAAFRTKVQDHSKAEDEWKAQVARGR------QEAERKNSLISSLEEEVSI---LNRQVLE 1243
Cdd:TIGR02169  530 LGSVGERYATAIEVAAgNRLNNVVVEDDAVAKEAIELLKRRKAGRatflplNKMRDERRDLSILSEDGVIgfaVDLVEFD 609

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1244 KEGESKEL----KRLVMAESEKSQKLEERLRLLQAET-----------ASNSARAAE-RSSALREEVQSLREEAEKQRVA 1307
Cdd:TIGR02169  610 PKYEPAFKyvfgDTLVVEDIEAARRLMGKYRMVTLEGelfeksgamtgGSRAPRGGIlFSRSEPAELQRLRERLEGLKRE 689

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1308 SENLRQELTSQAERAEELGQELKAWQEKffqkeqaLSTLQLEhtstqalvsellpakhlcqqlqaeqaaaekrhREELEQ 1387
Cdd:TIGR02169  690 LSSLQSELRRIENRLDELSQELSDASRK-------IGEIEKE--------------------------------IEQLEQ 730

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1388 SKQAAGGLRAELLRAQRElgelipLRQKVAEQERTAQQLRAEKASYAEQLSMLKKAhgllaeenrglgeRANLGRQFLEV 1467
Cdd:TIGR02169  731 EEEKLKERLEELEEDLSS------LEQEIENVKSELKELEARIEELEEDLHKLEEA-------------LNDLEARLSHS 791

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1468 ELDQAREKYvQELAAVRADAETRLAEVQREAQSTARELEVMTAKYEGAKVKVLEERQRFQEERQkltaQVEQLEVFQREQ 1547
Cdd:TIGR02169  792 RIPEIQAEL-SKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEK----EIENLNGKKEEL 866

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1548 TKQVEELSKKLADSDQASKVQQQKLKAVQAQGGESQQEAQRLQAQLNELQAQLSQKEQAAEHYKLQMekakTHYDAKKQQ 1627
Cdd:TIGR02169  867 EEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEEL----SEIEDPKGE 942

                          890       900
                   ....*....|....*....|....*....
gi 1370459521 1628 NQELQEQLRSLEQLQKENKELRAEAERLG 1656
Cdd:TIGR02169  943 DEEIPEEELSLEDVQAELQRVEEEIRALE 971
PTZ00121 PTZ00121
MAEBL; Provisional
 217-856 9.53e-16

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 84.04  E-value: 9.53e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  217 RRLKKQLADERSNRDELELELAEN-RKLLTEKDAQIAMMQQRIDRLALLNEKQAASPLEPKELEELRDKNEsltMRLHET 295
Cdd:PTZ00121  1224 KKAEAVKKAEEAKKDAEEAKKAEEeRNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADE---AKKAEE 1300

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  296 LKQCQDLKtEKSQMDRKINQLSEEngdlsfklrefASHLQQLQDALNELTEEHSKATQEWLEKQAQLEKELSAALQDKKC 375
Cdd:PTZ00121  1301 KKKADEAK-KKAEEAKKADEAKKK-----------AEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEA 1368

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  376 LEEKNEILQGKLSQLEEHLSQLQDNPPQEKGEVLGDVLQLETLKQEAATLAANNTQLQArvemlETERGQQEAKLLAERG 455
Cdd:PTZ00121  1369 AEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKA-----EEKKKADEAKKKAEEA 1443

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  456 HFEEEkqqlsslitdlqssisnlsqAKEELEQASQAHGARLTAQVASLTSELTTlnatiqqqdqelaglKQQAKEKQAQL 535
Cdd:PTZ00121  1444 KKADE--------------------AKKKAEEAKKAEEAKKKAEEAKKADEAKK---------------KAEEAKKADEA 1488

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  536 AQTLQQQEQASQGLRHQVEQlssslKQKEQQLKEVAEKQEATRQDHAQQLATAAEEREASLRERDAALKQLEALEKekaa 615
Cdd:PTZ00121  1489 KKKAEEAKKKADEAKKAAEA-----KKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKK---- 1559

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  616 kleilqqqlqvANEARDSAQTSvtQAQREKAELSRKVEELQAcVETARQEQheaQAQVAELELQLRSEQQKATEKERVAQ 695
Cdd:PTZ00121  1560 -----------AEEKKKAEEAK--KAEEDKNMALRKAEEAKK-AEEARIEE---VMKLYEEEKKMKAEEAKKAEEAKIKA 1622

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  696 EKDQLQEQLQALKESLKVTKgslEEEKRRAADALEEQQRCISELKAETRSLVEQHKRERKELEEERAGRKGLEARLQQLG 775
Cdd:PTZ00121  1623 EELKKAEEEKKKVEQLKKKE---AEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAE 1699

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  776 EAHQAEtEVLRRELAEAMAAQHTAESECEQLVKEVAAWRERYEDSQQ-EEAQYGAMFQEQLMTLKEECEKARQELQEAKE 854
Cdd:PTZ00121  1700 EAKKAE-ELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKaEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKE 1778


                   ..
gi 1370459521  855 KV 856
Cdd:PTZ00121  1779 AV 1780
HkD_SF cd22211
Hook domain-containing proteins superfamily; The Hook domain superfamily includes Hook adaptor ...
 8-136 1.45e-14

Hook domain-containing proteins superfamily; The Hook domain superfamily includes Hook adaptor proteins, Hook-related proteins and nuclear mitotic apparatus protein (NuMA). They share an N-terminal conserved globular Hook domain, which folds as a variant of the helical calponin homology (CH) domain with an extended alpha-helix. The Hook domain is responsible for the binding of microtubule. The Hook family includes microtubule-binding proteins, Hook1-3. Hook1 is required for spermatid differentiation. Hook2 contributes to the establishment and maintenance of centrosome function. Hook3 is an adaptor protein for microtubule-dependent intracellular vesicle and protein trafficking, and is involved in Golgi and endosome transport. Hook proteins are components of the FTS/Hook/FHIP complex (FHF complex), which may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting (HOPS) complex. The Hook-related protein (HkRP) family includes Daple, Girdin and Gipie. Daple, also called Dvl-associating protein with a high frequency of leucine residues, or coiled-coil domain-containing protein 88C(CCDC88C), or Hook-related protein 2 (HkRP2), is a novel non-receptor nucleotide exchange factor (GEF) required for activation of guanine nucleotide-binding proteins (G-proteins) during non-canonical Wnt signaling. Girdin, also called Akt phosphorylation enhancer (APE), or coiled-coil domain-containing protein 88A (CCDC88A), or G alpha-interacting vesicle-associated protein (GIV), or Girders of actin filament, or Hook-related protein 1 (HkRP1), is a bifunctional modulator of guanine nucleotide-binding proteins (G proteins). Gipie, also called GRP78-interacting protein induced by ER stress, or coiled-coil domain-containing protein 88B(CCDC88B), or brain leucine zipper domain-containing protein, or Hook-related protein 3 (HkRP3), is a novel actin cytoskeleton-binding protein and Akt substrate that regulates cell migratory responses in various biological contexts. NuMA, also called nuclear mitotic apparatus protein 1, or nuclear matrix protein-22 (NMP-22), or SP-H antigen, is a microtubule (MT)-binding protein that plays a role in the formation and maintenance of the spindle poles and the alignment and the segregation of chromosomes during mitotic cell division.


Pssm-ID: 411792  Cd Length: 145  Bit Score: 72.69  E-value: 1.45e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521    8 GAALLSWVNSLHVADPVEAVLQLQDCSIFIKIIDRIHGTEEGQQILKQPVS--------ERLDFVCSFLQKNRKH----P 75
Cdd:cd22211      1 EAALLAWINTFPLSSPVESLDDLSDGVVLAEILSQIDPSYFDSEWLESRDSsdnwvlklNNLKKLYRSLSKYYREvlgqQ 80

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1370459521   76 SSPECLVSAQKVLE-GSELELAKMTMLLLYHSTMSSKSPRD---WEQFEYKIQAELAVILKFVLD 136
Cdd:cd22211     81 LSDLPLPDLSAIARdGDEEEIVKLLELVLGAAVQCENKEEYiarIQQLDESTQAELMLIIQEVLE 145
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 415-746 4.04e-14

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 78.56  E-value: 4.04e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  415 LETLKQEAATLAANNTQLQARVEMLETERGQQEAKLLAERGHFEEEKQQLSSLITDLQSSISNLSQAKEELEQASQAHgA 494
Cdd:TIGR02168  679 IEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKEL-T 757

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  495 RLTAQVASLTSELTTLNATIQQQDQELAGLKQQAKEkqaqLAQTLQQQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQ 574
Cdd:TIGR02168  758 ELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQ----LKEELKALREALDELRAELTLLNEEAANLRERLESLERRI 833

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  575 EATRQdHAQQLATAAEEREASLRERDAALKQLEALEKEKAAKLEILQQQLQVANEARDSAQTSVTQAQREKAELSRKVEE 654
Cdd:TIGR02168  834 AATER-RLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSE 912

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  655 LQACVETARQEQHEAQAQVAELELQLRSEQQKATEKERVAQE------------KDQLQEQLQALK-------------- 708
Cdd:TIGR02168  913 LRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEeaealenkieddEEEARRRLKRLEnkikelgpvnlaai 992

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|.
gi 1370459521  709 ---ESLKVTKGSLEEEKRRAADALEEQQRCISELKAETRSL 746
Cdd:TIGR02168  993 eeyEELKERYDFLTAQKEDLTEAKETLEEAIEEIDREARER 1033
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 223-900 5.90e-14

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 77.96  E-value: 5.90e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  223 LADERSNRDELELELAENRKLLTEKDAQIAMMQQRIDrlALLNEKQAASPLEPKELEELRDKNESLTMRLHETLKQCQdl 302
Cdd:pfam12128  246 LQQEFNTLESAELRLSHLHFGYKSDETLIASRQEERQ--ETSAELNQLLRTLDDQWKEKRDELNGELSAADAAVAKDR-- 321

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  303 ktekSQMDRKINQLSEENGDLSFKLREFASHLQQLQDALNELTEEHSKATQEWLEKQAQLEKELSAALQDkkcleeknei 382
Cdd:pfam12128  322 ----SELEALEDQHGAFLDADIETAAADQEQLPSWQSELENLEERLKALTGKHQDVTAKYNRRRSKIKEQ---------- 387

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  383 LQGKLSQLEEHLSQLQDNPPQEKGEVLGDVLQLETLKQEAATLAANNtqlqARVEMLETERGQQEAKLLAERGHFEEEkq 462
Cdd:pfam12128  388 NNRDIAGIKDKLAKIREARDRQLAVAEDDLQALESELREQLEAGKLE----FNEEEYRLKSRLGELKLRLNQATATPE-- 461

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  463 qlssLITDLQSSISNLSQAKEELEQAsqahgarlTAQVASLTSELTTLNATIQQQDQELAGLKQQAKEKQAQLAQTLQQQ 542
Cdd:pfam12128  462 ----LLLQLENFDERIERAREEQEAA--------NAEVERLQSELRQARKRRDQASEALRQASRRLEERQSALDELELQL 529

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  543 EQASQGLRHqveQLSSSLKQKEQQLKEVAEKQEATRQDHAQQLATAAEEREASLRERDAALKQLEAleKEKAAKLEILQQ 622
Cdd:pfam12128  530 FPQAGTLLH---FLRKEAPDWEQSIGKVISPELLHRTDLDPEVWDGSVGGELNLYGVKLDLKRIDV--PEWAASEEELRE 604

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  623 QLQVANEARDSAQTSVTQAQREKAELSRKVEELQACVETARQEQHEAQAQVAELELQLRSEQQKATEKerVAQEKDQLQE 702
Cdd:pfam12128  605 RLDKAEEALQSAREKQAAAEEQLVQANGELEKASREETFARTALKNARLDLRRLFDEKQSEKDKKNKA--LAERKDSANE 682

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  703 QLQALKESLKVTKGSLEeekrraaDALEEQQRCISELKaetrslVEQHKRERKELEEERAGRKGLEARLQQLGEAHQAET 782
Cdd:pfam12128  683 RLNSLEAQLKQLDKKHQ-------AWLEEQKEQKREAR------TEKQAYWQVVEGALDAQLALLKAAIAARRSGAKAEL 749

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  783 EVLRRELAEAMAAQHTAE---SECEQLVKEVAAWRERYEDSQQEEAQYGAMFQEQLMT----LKEECEKARQELQEAKEK 855
Cdd:pfam12128  750 KALETWYKRDLASLGVDPdviAKLKREIRTLERKIERIAVRRQEVLRYFDWYQETWLQrrprLATQLSNIERAISELQQQ 829

                          650       660       670       680
                   ....*....|....*....|....*....|....*....|....*
gi 1370459521  856 VAGIESHSELQISRQQNELAELHANLARALQQVQEKEVRAQKLAD 900
Cdd:pfam12128  830 LARLIADTKLRRAKLEMERKASEKQQVRLSENLRGLRCEMSKLAT 874
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 215-926 7.33e-14

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 77.80  E-value: 7.33e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  215 QMRRLKKQLADERSNRDELELELAENRKLLTEKDAQIAmmqQRIDRLALLNEKqaASPLEPKELEELRDKNESLTMRLHE 294
Cdd:TIGR02169  231 EKEALERQKEAIERQLASLEEELEKLTEEISELEKRLE---EIEQLLEELNKK--IKDLGEEEQLRVKEKIGELEAEIAS 305

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  295 TLKQCQDLKTEKSQMDRKINQLSEENGDLSFKLREFASHLQQLQDALNELTEEHSKATQEWLEKQAQLE---KELSAALQ 371
Cdd:TIGR02169  306 LERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEevdKEFAETRD 385

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  372 DKKCLEEKNEILQGKLSQLEEHLSQLQDNPPQEKGEvlgdvlqLETLKQEAATLAANNTQLQARVEMLETERGQQEAKLL 451
Cdd:TIGR02169  386 ELKDYREKLEKLKREINELKRELDRLQEELQRLSEE-------LADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLE 458

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  452 AERGHFEEEKQQLSSLITDLQSSISNLSQAKEELEQASQAHGARLTAQ----------------VASLTSELTT------ 509
Cdd:TIGR02169  459 QLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVrggraveevlkasiqgVHGTVAQLGSvgerya 538

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  510 ----------LNATIQQQDQELAGLKQQAKEKQAQLA------QTLQQQEQASQGLRHQVEQLSSSLKQKEQQLKE---- 569
Cdd:TIGR02169  539 taievaagnrLNNVVVEDDAVAKEAIELLKRRKAGRAtflplnKMRDERRDLSILSEDGVIGFAVDLVEFDPKYEPafky 618

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  570 -------VAEKQEATRQDHAQQLATAAEE--------REASLRERDAALKQLEALEK--EKAAKLEILQQQLQVANEARD 632
Cdd:TIGR02169  619 vfgdtlvVEDIEAARRLMGKYRMVTLEGElfeksgamTGGSRAPRGGILFSRSEPAElqRLRERLEGLKRELSSLQSELR 698

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  633 SAQTSVTQAQREKAELSRKVEELQACVETARQEQHEAQAQVAELELQLRSEQQKAT----EKERVAQEKDQLQEQLQALK 708
Cdd:TIGR02169  699 RIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIEnvksELKELEARIEELEEDLHKLE 778

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  709 ESLKVTKGSLEEEK----RRAADALEEQQRCI----SELKAETRSLVEQHKRERKELEEERAGRKGLEAR---LQQLGEA 777
Cdd:TIGR02169  779 EALNDLEARLSHSRipeiQAELSKLEEEVSRIearlREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQiksIEKEIEN 858

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  778 HQAETEVLRRELAEAMAAQHTAESECEQLVKEVAAWRERYEDSQQEEAQYGAMFQE---QLMTLKEECEKARQELQEAKE 854
Cdd:TIGR02169  859 LNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKkrkRLSELKAKLEALEEELSEIED 938

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  855 KVAGIESHSE---------LQISRQQNELAELHANLARALQQVQEKEVRAQKLADDLSTLQEKMAATSKEVARLETLVRK 925
Cdd:TIGR02169  939 PKGEDEEIPEeelsledvqAELQRVEEEIRALEPVNMLAIQEYEEVLKRLDELKEKRAKLEEERKAILERIEEYEKKKRE 1018


                   .
gi 1370459521  926 A 926
Cdd:TIGR02169 1019 V 1019
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 236-920 1.26e-13

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 77.03  E-value: 1.26e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  236 ELAENRKLLTEKDAQIAMMQQRIDRLALLNEKQaasplepKELEELRDKNESLtmRLHETLKQCQDLKTEKSQMDRKINQ 315
Cdd:TIGR02169  178 ELEEVEENIERLDLIIDEKRQQLERLRREREKA-------ERYQALLKEKREY--EGYELLKEKEALERQKEAIERQLAS 248

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  316 LSEENGDLSFKLREFASHLQQLQDALNELTEEHSKATQEWL----EKQAQLEKELSAALQDKKCLEEKNEILQGKLSQLE 391
Cdd:TIGR02169  249 LEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQlrvkEKIGELEAEIASLERSIAEKERELEDAEERLAKLE 328

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  392 EHLSQLQDNPPQEKGEVLGDVLQLETLKQEAATLAANNTQLQARVEMLETERGQQEAKLLAERGHFEEEKQQLSSLITDL 471
Cdd:TIGR02169  329 AEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKREL 408

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  472 QSSISNLSQAKEELEQASQAHgARLTAQVASLTSELTTLNATIQQQDQELaglkQQAKEKQAQLAQTLQQQEQASQGLRH 551
Cdd:TIGR02169  409 DRLQEELQRLSEELADLNAAI-AGIEAKINELEEEKEDKALEIKKQEWKL----EQLAADLSKYEQELYDLKEEYDRVEK 483

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  552 QVEQLSSSLKQKEQQLKEVAEKQEATR------------------------QDHAQQLATAAEEREAS------------ 595
Cdd:TIGR02169  484 ELSKLQRELAEAEAQARASEERVRGGRaveevlkasiqgvhgtvaqlgsvgERYATAIEVAAGNRLNNvvveddavakea 563

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  596 ---LRER-----------------------------DAALKQLEALEKEKAAKLEILQQQLQVAN--EARD--------- 632
Cdd:TIGR02169  564 ielLKRRkagratflplnkmrderrdlsilsedgviGFAVDLVEFDPKYEPAFKYVFGDTLVVEDieAARRlmgkyrmvt 643

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  633 -------------------SAQTSVTQAQREKA-ELSRKVEELQACVETARQEQHEAQAQVAELELQLRSEQQKATEK-- 690
Cdd:TIGR02169  644 legelfeksgamtggsrapRGGILFSRSEPAELqRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIek 723

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  691 --ERVAQEKDQLQEQLQALKESLKVTKGSLEEEKRRAAD---ALEEQQRCISELKAETRSLvEQHKRERKELEEERAGRK 765
Cdd:TIGR02169  724 eiEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKEleaRIEELEEDLHKLEEALNDL-EARLSHSRIPEIQAELSK 802

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  766 GLEARLQQLGEAHQAETEVLRRELAEAMaaqhtAESECEQLVKEVAAWRERYEDSQQEEAQygamFQEQLMTLKEECEKA 845
Cdd:TIGR02169  803 LEEEVSRIEARLREIEQKLNRLTLEKEY-----LEKEIQELQEQRIDLKEQIKSIEKEIEN----LNGKKEELEEELEEL 873

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1370459521  846 RQELQEAKEKVAGIEShselQISRQQNELAELHANLARALQQVQEKEVRAQKLADDLSTLQEKMAATSKEVARLE 920
Cdd:TIGR02169  874 EAALRDLESRLGDLKK----ERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDE 944
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
430-922 4.98e-13

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 74.69  E-value: 4.98e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  430 TQLQARVEMLETERgqqeAKLLAERGHFEEEKQQLSSLITDLQSSISNLSQAKEELEqasqahgarltaqvaSLTSELTT 509
Cdd:PRK02224   202 KDLHERLNGLESEL----AELDEEIERYEEQREQARETRDEADEVLEEHEERREELE---------------TLEAEIED 262

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  510 LNATIQQQDQELAGLKQQAKEKQAQLAQTLQQQEqasqGLRHQVEQLSSSLKQKEQQLKEVAEKQEATRQDHAQQLATAA 589
Cdd:PRK02224   263 LRETIAETEREREELAEEVRDLRERLEELEEERD----DLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQ 338

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  590 EEREASLRERDAAlKQLEALEKEKAAKLEILQQQLQVANEARDSAQTSVTQAQREKAELSRKV-------EELQACVETA 662
Cdd:PRK02224   339 AHNEEAESLREDA-DDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFgdapvdlGNAEDFLEEL 417

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  663 RQEQHEAQAQVAELELQLRSEQQKATEKER---------------------VAQEKDQLQEQLQALKESLKVTKGSLEEE 721
Cdd:PRK02224   418 REERDELREREAELEATLRTARERVEEAEAlleagkcpecgqpvegsphveTIEEDRERVEELEAELEDLEEEVEEVEER 497

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  722 KRRAADALEEQQRCisELKAETRSLVEQHKRERkeleeeragRKGLEARLQQLGEAHQAETEvLRRELAEAMAAQHTAES 801
Cdd:PRK02224   498 LERAEDLVEAEDRI--ERLEERREDLEELIAER---------RETIEEKRERAEELRERAAE-LEAEAEEKREAAAEAEE 565

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  802 ECEQLVKEVAAWRERYEDSQQEEAQYGAMfqEQLMTLKEECEKARQELQEAKEKVAGI------------ESHSELQISR 869
Cdd:PRK02224   566 EAEEAREEVAELNSKLAELKERIESLERI--RTLLAAIADAEDEIERLREKREALAELnderrerlaekrERKRELEAEF 643

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1370459521  870 QQNELAELHANLARALQQVQEKEVRAQKLADDLSTLQEKMAATSKEVARLETL 922
Cdd:PRK02224   644 DEARIEEAREDKERAEEYLEQVEEKLDELREERDDLQAEIGAVENELEELEEL 696
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 566-1269 5.35e-13

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 74.87  E-value: 5.35e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  566 QLKEVAEKQEATRQDHAQQLATAAEEREASLRERDAALKQLEALEKEKAA-KLEILQQQLQVAN--EARDSAQTSVTQAQ 642
Cdd:pfam12128  213 PPKSRLNRQQVEHWIRDIQAIAGIMKIRPEFTKLQQEFNTLESAELRLSHlHFGYKSDETLIASrqEERQETSAELNQLL 292

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  643 REK-AELSRKVEELQACVETARQEQHEAQAQVAELELQLRSEQQKATEKERVAQEK-DQLQEQLQALKESLKVTKGSL-- 718
Cdd:pfam12128  293 RTLdDQWKEKRDELNGELSAADAAVAKDRSELEALEDQHGAFLDADIETAAADQEQlPSWQSELENLEERLKALTGKHqd 372

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  719 --EEEKRRAADALEEQQRCISELKAETRslveqhkrerkeleeeragrKGLEARLQQLGEAhQAETEVLRRELAEAMAAQ 796
Cdd:pfam12128  373 vtAKYNRRRSKIKEQNNRDIAGIKDKLA--------------------KIREARDRQLAVA-EDDLQALESELREQLEAG 431

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  797 HTAESECEQLVKEVAAWreryEDSQQEEAQYGAMFQEQLMTLKEECEKARQELQEAKEKVagieshselqiSRQQNELAE 876
Cdd:pfam12128  432 KLEFNEEEYRLKSRLGE----LKLRLNQATATPELLLQLENFDERIERAREEQEAANAEV-----------ERLQSELRQ 496

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  877 LHANLARALQQVQEKEVRAQKLADDLSTLQEKMAATSKEVarLETLVRKAGEQQETASRELVKEPARAGDRQPEWLEEQ- 955
Cdd:pfam12128  497 ARKRRDQASEALRQASRRLEERQSALDELELQLFPQAGTL--LHFLRKEAPDWEQSIGKVISPELLHRTDLDPEVWDGSv 574

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  956 -QGRQFCSTQAALQAMER-EAEQMGNELERLRAALMESQGQQQEERGQQEREVARLTQERGRAQADLALEKAARAELEMR 1033
Cdd:pfam12128  575 gGELNLYGVKLDLKRIDVpEWAASEEELRERLDKAEEALQSAREKQAAAEEQLVQANGELEKASREETFARTALKNARLD 654

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1034 LQNALNEQRVEFATLQEALahalteKEGKDQELAKLRGLEAAQIKELEELRQTVKQLKEQLakkekehasgsgaqseaag 1113
Cdd:pfam12128  655 LRRLFDEKQSEKDKKNKAL------AERKDSANERLNSLEAQLKQLDKKHQAWLEEQKEQK------------------- 709

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1114 rTEPTGPKLEALRAEVSKLEQQCqkqqeqaDSLERSLEAERASRAERDSALETlqgQLEEKAQELGHSQSALASAQRELA 1193
Cdd:pfam12128  710 -REARTEKQAYWQVVEGALDAQL-------ALLKAAIAARRSGAKAELKALET---WYKRDLASLGVDPDVIAKLKREIR 778

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1194 AFRTKV----QDHSKAEDEWKAQVARGRQEAERKNSLISSLEEEVSILNRQVLEKEGESKELKRLVMAESEKSQKLEERL 1269
Cdd:pfam12128  779 TLERKIeriaVRRQEVLRYFDWYQETWLQRRPRLATQLSNIERAISELQQQLARLIADTKLRRAKLEMERKASEKQQVRL 858
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 217-715 1.80e-12

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 72.75  E-value: 1.80e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  217 RRLKKQLADERSNRDELELELAENRKLLTEKDAQIAMMQQRIDRLALLNEKQAaspLEPKELEELRDKNESLTMRLHETL 296
Cdd:TIGR04523  162 NDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKLELLLSNLKKKIQKNK---SLESQISELKKQNNQLKDNIEKKQ 238

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  297 KQCQDLKTEKSQMDRKINQLSEENGDLSFKLREFASHLQQLQDALNELTEEHSKATQEWL----EKQAQLEKELSAALQD 372
Cdd:TIGR04523  239 QEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISdlnnQKEQDWNKELKSELKN 318

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  373 KkclEEKNEILQGKLSQLEEHLSQLQDnppqekgevlgdvlQLETLKQEAATLAANNTQLQARVEmletERGQQEAKLLA 452
Cdd:TIGR04523  319 Q---EKKLEEIQNQISQNNKIISQLNE--------------QISQLKKELTNSESENSEKQRELE----EKQNEIEKLKK 377

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  453 ERGHFEEEKQQLSSLITDLQSSISNLSQAKEELEQASQahgaRLTAQVASLTSELTTLNATIQQQDQELAGLKQQAKEKQ 532
Cdd:TIGR04523  378 ENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIK----KLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKE 453

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  533 AQLAQTLQQQEQASQGL----------RHQVEQLSSSLKQKEQQLKEVA------EKQEATRQDHAQQLATAAEEREASL 596
Cdd:TIGR04523  454 LIIKNLDNTRESLETQLkvlsrsinkiKQNLEQKQKELKSKEKELKKLNeekkelEEKVKDLTKKISSLKEKIEKLESEK 533

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  597 RERDAALKQLEALEKE-----KAAKLEILQQQLQVANEARDSAQTSVTQAQREKAELsrkVEELQACVETARQEQHEAQA 671
Cdd:TIGR04523  534 KEKESKISDLEDELNKddfelKKENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQEL---IDQKEKEKKDLIKEIEEKEK 610

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|....*...
gi 1370459521  672 QVAELELQLRSEQQK----ATEKERVAQEKDQLQEQLQALKESLKVTK 715
Cdd:TIGR04523  611 KISSLEKELEKAKKEneklSSIIKNIKSKKNKLKQEVKQIKETIKEIR 658
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1014-1697 1.98e-12

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 73.18  E-value: 1.98e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1014 GRAQADLALEKAaRAELEM------RLQNALNEQRVEFATLQEALAHALTEKEGKDQE--------LAKLRGLEA--AQI 1077
Cdd:TIGR02169  164 GVAEFDRKKEKA-LEELEEveenieRLDLIIDEKRQQLERLRREREKAERYQALLKEKreyegyelLKEKEALERqkEAI 242

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1078 -KELEELRQTVKQLKEQLAKKEKEHASGSGAQSEAAGRTEPTGP--------KLEALRAEVSKLEQQCQKQQEQADSLER 1148
Cdd:TIGR02169  243 eRQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEeeqlrvkeKIGELEAEIASLERSIAEKERELEDAEE 322

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1149 SLEAERASRAERDSALETLQGQLEEKAQELGHSQSALASAQRELAAFRTKVQDHSKAEDEWKAQVargrqeaerknsliS 1228
Cdd:TIGR02169  323 RLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDEL--------------K 388

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1229 SLEEEVSILNRqvlekegESKELKRLVMAESEKSQKLEERLRLLQAETasnsARAAERSSALREEVQSLREEAEKQRvas 1308
Cdd:TIGR02169  389 DYREKLEKLKR-------EINELKRELDRLQEELQRLSEELADLNAAI----AGIEAKINELEEEKEDKALEIKKQE--- 454

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1309 enlrqeltsqaERAEELGQELKAWQEKFFQKEQALSTLQLEHTSTQALVSELLPAKhlcqQLQAEQAAAEKRHREELEQS 1388
Cdd:TIGR02169  455 -----------WKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQA----RASEERVRGGRAVEEVLKAS 519

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1389 KQAAGGLRAELLRAQRELGELIP------LRQKVAEQERTAQQ----LRAEKASYAEQLSMLKKAHGLLaeENRGLGERA 1458
Cdd:TIGR02169  520 IQGVHGTVAQLGSVGERYATAIEvaagnrLNNVVVEDDAVAKEaielLKRRKAGRATFLPLNKMRDERR--DLSILSEDG 597

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1459 NLGRQFLEVELDQARE---KYVQELAAVRADAET--RLAEVQREAQSTARELE---VMTAKY------EGAKVKVLEERQ 1524
Cdd:TIGR02169  598 VIGFAVDLVEFDPKYEpafKYVFGDTLVVEDIEAarRLMGKYRMVTLEGELFEksgAMTGGSraprggILFSRSEPAELQ 677

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1525 RFQEERQKLTAQVEQLEVFQREQTKQVEELSKKLADSdqaskvqQQKLKAVQAQGGESQQEAQRLQAQLNELQAQLSQKE 1604
Cdd:TIGR02169  678 RLRERLEGLKRELSSLQSELRRIENRLDELSQELSDA-------SRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLE 750

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1605 QAAEHYKLQMEKAKTHYDAKKQQNQELQEQLRSLEQ--LQKENKELRAEAERLGHELQQAGLKTKEAEQTCRHLTAQVRS 1682
Cdd:TIGR02169  751 QEIENVKSELKELEARIEELEEDLHKLEEALNDLEArlSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEY 830

                          730
                   ....*....|....*
gi 1370459521 1683 LEAQVAHADQQLRDL 1697
Cdd:TIGR02169  831 LEKEIQELQEQRIDL 845
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 350-1102 6.91e-12

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 71.16  E-value: 6.91e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  350 KATQEWLEKQAQLEKELSAALQDKKcLEEKNEILQGKLSQLEEHLSQLQDNPPQEKGEVLGDVLQLETLKQEAATLAANN 429
Cdd:pfam02463  146 IIAMMKPERRLEIEEEAAGSRLKRK-KKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEE 224

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  430 TQLQARVEMLETERGQQEAKLLAERGHFEEEKQQLSSLITDLQSSISNLSQAKEELEQASQAHGARLTAQVASLTSELTT 509
Cdd:pfam02463  225 YLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLK 304

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  510 LNATIQQQDQELAGLKQQAKEKQAQLAqtlqqqeqasqglrhQVEQLSSSLKQKEQQLKEVAEKQEATRQDHAQQLATAA 589
Cdd:pfam02463  305 LERRKVDDEEKLKESEKEKKKAEKELK---------------KEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLE 369

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  590 EEREASLRERDAALKQLEALEKEKAAKLEILQQQLQVANEARDSAQTSVTQAQREKAELSRKVEELQACVETArQEQHEA 669
Cdd:pfam02463  370 QLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELK-QGKLTE 448

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  670 QAQVAELELQLRSEQQKATEKERVAQEKDQLQEQLQALKESLKVTKGSLEEEKRRAADALEEQQRCISELKAETRSLVEQ 749
Cdd:pfam02463  449 EKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAH 528

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  750 HKRERKELEEERAGRKGLEARLQQLGEAHQAETEVLRRELAEAMAAQHTAESECEQLVKEVAAWRERYEDSQQEEAQYGA 829
Cdd:pfam02463  529 GRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQL 608

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  830 MFQEQLMTLKEECEKARQELQEAKEKVAGIESHSELQISRQQNELAELHANLARALQQVQEKEVRAQKLADDLSTLQEKM 909
Cdd:pfam02463  609 DKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESE 688

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  910 AATSKEVARLETLVRKAGEQQETASRELVKEPARAGDRQPEWLEEQQGRQFCSTQAALQAMEREA----EQMGNELERLR 985
Cdd:pfam02463  689 LAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEksrlKKEEKEEEKSE 768

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  986 AALMESQGQQQEERGQQEREVARLTQERGRAQADLA------LEKAARAELEMRLQNALNEQRVEFATLQEALAHALTEK 1059
Cdd:pfam02463  769 LSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRaleeelKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKL 848

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|...
gi 1370459521 1060 EGKDQELAKLRGLEAAQIKELEELRQTVKQLKEQLAKKEKEHA 1102
Cdd:pfam02463  849 EKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESK 891
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 875-1731 1.25e-11

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 70.48  E-value: 1.25e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  875 AELHANLARALQQVQEKEVRAQKLADDLSTLQEKMAATSKEVARLETLVRKAGEQQETASRELVKEpARAGDRQPEWLEe 954
Cdd:TIGR02169  166 AEFDRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAERYQALLKEKREYEGYELLKE-KEALERQKEAIE- 243

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  955 qqgRQFCSTQAALQAMEREAEQMGNELERLRAALMEsqgQQQEERGQQEREVARLTQERGRAQADLALEKAARAELEMRL 1034
Cdd:TIGR02169  244 ---RQLASLEEELEKLTEEISELEKRLEEIEQLLEE---LNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIAEKEREL 317

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1035 QNALNEQRVEFATLQEALAhaltEKEGKDQELAKLRGLEAAQIKELEELRQTVKQLKEQLAKKEKEHASGSGAQSEAAGR 1114
Cdd:TIGR02169  318 EDAEERLAKLEAEIDKLLA----EIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREK 393

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1115 TEPTGPKLEALRAEVSKLEQQCQKQQEQADSLERSLEAERASRAERDSALETLQGQLEEKAQELGHSQSALASAQRELAA 1194
Cdd:TIGR02169  394 LEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYD 473

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1195 FRTKVQDHSKAEDEWKAQVARgrQEAERKnslISSLEEEVSILNRQVLEK--EGESKELKRLVMAESEKSQKLE----ER 1268
Cdd:TIGR02169  474 LKEEYDRVEKELSKLQRELAE--AEAQAR---ASEERVRGGRAVEEVLKAsiQGVHGTVAQLGSVGERYATAIEvaagNR 548

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1269 LRLLQAETASNSARAAE---RSSALREEVQSLREEAEKQRVASENLRQELTSQAERAEELGQELKAWQEKFFQKEQALST 1345
Cdd:TIGR02169  549 LNNVVVEDDAVAKEAIEllkRRKAGRATFLPLNKMRDERRDLSILSEDGVIGFAVDLVEFDPKYEPAFKYVFGDTLVVED 628

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1346 LQL--EHTSTQALVS---ELLPAKHLCQQLQAEQAAAEKRHREELEQSKQaaggLRAELLRAQRELGELiplRQKVAEQE 1420
Cdd:TIGR02169  629 IEAarRLMGKYRMVTlegELFEKSGAMTGGSRAPRGGILFSRSEPAELQR----LRERLEGLKRELSSL---QSELRRIE 701

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1421 RTAQQLRAEKASYAEQLSMLKKAHGLLAEENRGLGERANLGRQFLEvELDQAREKYVQELAAVRAdaetRLAEVQREAQS 1500
Cdd:TIGR02169  702 NRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLS-SLEQEIENVKSELKELEA----RIEELEEDLHK 776

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1501 TARELEVMTAKYEGAKVKVLEERQRFQEE-RQKLTAQVEQLEvfqreqtkqveelskkladsdqaskvqqQKLKAVQAQG 1579
Cdd:TIGR02169  777 LEEALNDLEARLSHSRIPEIQAELSKLEEeVSRIEARLREIE----------------------------QKLNRLTLEK 828

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1580 GESQQEAQRLQAQLNELQAQLSQKEQAAEHYKLQMEKakthydaKKQQNQELQEQlrsLEQLQKENKELRAEAERLGHEL 1659
Cdd:TIGR02169  829 EYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEE-------LEEELEELEAA---LRDLESRLGDLKKERDELEAQL 898

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1370459521 1660 QQAGLKTKEAEQTCRHLTAQVRSLEAQVAHADQQLRDLGKfqvatdalKSREPQAKPQLDLSIDSLDLSCEE 1731
Cdd:TIGR02169  899 RELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIED--------PKGEDEEIPEEELSLEDVQAELQR 962
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
460-1100 1.40e-11

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 70.33  E-value: 1.40e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  460 EKQQLSSLITDLQSSISNLSQAKEELEQASQAhgARLTAQVASLTSELTTLNATIQQQDQELAGLKQQAKEKQAQLAQTL 539
Cdd:COG4913    219 EEPDTFEAADALVEHFDDLERAHEALEDAREQ--IELLEPIRELAERYAAARERLAELEYLRAALRLWFAQRRLELLEAE 296

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  540 QqqeqasQGLRHQVEQLSSSLKQKEQQLKEVAEKQEATRQDHAQqlataaeereASLRERDAALKQLEALEKEKA---AK 616
Cdd:COG4913    297 L------EELRAELARLEAELERLEARLDALREELDELEAQIRG----------NGGDRLEQLEREIERLERELEereRR 360

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  617 LEILQQQLQVANEA----RDSAQTSVTQAQREKAELSRKVEELQACVETARQEQHEAQAQVAELELQLRS-EQQKATEKE 691
Cdd:COG4913    361 RARLEALLAALGLPlpasAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASlERRKSNIPA 440

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  692 RVAQEKDQLQEQLQALKESLK-----VTKGSLEEEKRRAADAL----------EEQQ-----RCISELKAETRSLVEQHK 751
Cdd:COG4913    441 RLLALRDALAEALGLDEAELPfvgelIEVRPEEERWRGAIERVlggfaltllvPPEHyaaalRWVNRLHLRGRLVYERVR 520

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  752 RERKELEEERAGRKGLEARLQ-QLGEAHQAetevLRRELAEAMAAqHTAESEcEQLVKE---------VAAWRERYE--D 819
Cdd:COG4913    521 TGLPDPERPRLDPDSLAGKLDfKPHPFRAW----LEAELGRRFDY-VCVDSP-EELRRHpraitragqVKGNGTRHEkdD 594

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  820 SQQEEAQY--GAMFQEQLMTLKEECEKARQELQEAKEKVAgieshselQISRQQNELAELHANLARaLQQVQEKEVRAQK 897
Cdd:COG4913    595 RRRIRSRYvlGFDNRAKLAALEAELAELEEELAEAEERLE--------ALEAELDALQERREALQR-LAEYSWDEIDVAS 665

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  898 LADDLSTLQEKMA---ATSKEVARLETLVRKAGEQQETASRELVKEPARAGDRQPEW--LEEQqgrqfcstQAALQAMER 972
Cdd:COG4913    666 AEREIAELEAELErldASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELeqAEEE--------LDELQDRLE 737

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  973 EAEQMGNELERLRAalmESQGQQQEERGQQEREVARLTQERGRAQADLAlekaaraelemRLQNALNEQRVEFATLQEAL 1052
Cdd:COG4913    738 AAEDLARLELRALL---EERFAAALGDAVERELRENLEERIDALRARLN-----------RAEEELERAMRAFNREWPAE 803

                          650       660       670       680
                   ....*....|....*....|....*....|....*....|....*....
gi 1370459521 1053 AHAL-TEKEGKDQELAKLRGLEAAQIKELEElrqtvkQLKEQLAKKEKE 1100
Cdd:COG4913    804 TADLdADLESLPEYLALLDRLEEDGLPEYEE------RFKELLNENSIE 846
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 402-1100 3.70e-11

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 68.84  E-value: 3.70e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  402 PQEKGEVLGDVLQLETLKQEAATLAANNTQ-------LQARVEMLETERGQQEAKLLAERGHFEEEKQQLSSLITDLQSS 474
Cdd:TIGR00618  162 SKEKKELLMNLFPLDQYTQLALMEFAKKKSlhgkaelLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREALQQTQQS 241

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  475 ISNLSQAKEELEQASQAHgaRLTAQVASLTSELTTLNATIQQQDQELaglKQQAKEKQAQLAQTLQQQEQASQGLRHQVE 554
Cdd:TIGR00618  242 HAYLTQKREAQEEQLKKQ--QLLKQLRARIEELRAQEAVLEETQERI---NRARKAAPLAAHIKAVTQIEQQAQRIHTEL 316

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  555 QLSSSLKQKEQQLKEVAEKQEATRQDHAQQLATAAEEREASLRERDAALKQLEALEKEKAAKLEILQQQLQVaneardsa 634
Cdd:TIGR00618  317 QSKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQHTLTQHIHTLQQQK-------- 388

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  635 qTSVTQAQREKAELSRKVEELQACVETARQEQHEAQAQVAELELQLRSEQQKATEKERVAQEkdQLQEQLQALKESLKVT 714
Cdd:TIGR00618  389 -TTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITC--TAQCEKLEKIHLQESA 465

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  715 KGSLEEEKrraadaLEEQQRCISELKAETRSLVEQHKRERKELEEERAGR-KGLEARLQQLG--EAHQAETEVLRRELAE 791
Cdd:TIGR00618  466 QSLKEREQ------QLQTKEQIHLQETRKKAVVLARLLELQEEPCPLCGScIHPNPARQDIDnpGPLTRRMQRGEQTYAQ 539

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  792 AMAAQHTAESECEQLVKEVAAWRERYEDSQQEEAQYGAMFQEqlmtLKEECEKARQELQEakekvagieshselqISRQQ 871
Cdd:TIGR00618  540 LETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNR----SKEDIPNLQNITVR---------------LQDLT 600

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  872 NELAELHANLARALQQVQEKEVRAQKLADDLSTLQEKMAATSKEVARLETLvrkageqQETASRELVKEPARAGDRQPEW 951
Cdd:TIGR00618  601 EKLSEAEDMLACEQHALLRKLQPEQDLQDVRLHLQQCSQELALKLTALHAL-------QLTLTQERVREHALSIRVLPKE 673

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  952 LEEQQgrqfcstQAALQAMEREAEQMGNELERLrAALMESQGQQQEERGQQEREVARLTQERGRAQADLALEKAARAELE 1031
Cdd:TIGR00618  674 LLASR-------QLALQKMQSEKEQLTYWKEML-AQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSL 745

                          650       660       670       680       690       700
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1370459521 1032 MRLQNALNEQRVEFATLQEALAHALTEKEGKDQELAKLRGLEAAQIKELEELRQTVKQLKEQLAKKEKE 1100
Cdd:TIGR00618  746 KELMHQARTVLKARTEAHFNNNEEVTAALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPS 814
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
205-828 4.31e-11

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 68.55  E-value: 4.31e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  205 MGDILQTPQFQMRRLKKQLADErsnrDELELELAENRKLLTEKDAQIAMMQQRIDRLAllnEKQAASPLEPKELEELRDK 284
Cdd:PRK03918   167 LGEVIKEIKRRIERLEKFIKRT----ENIEELIKEKEKELEEVLREINEISSELPELR---EELEKLEKEVKELEELKEE 239

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  285 NESLTMRLHETLKQCQDLKTEKSQMDRKINQLSEENGDLSFKLREFAShLQQLQDALNELTEEHSkatqEWLEKQAQLEK 364
Cdd:PRK03918   240 IEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKE-LKEKAEEYIKLSEFYE----EYLDELREIEK 314

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  365 ELSAALQDKKCLEEKNEILQGKLSQLEEhLSQLQDNPPQEKGEVLGDVLQLETLKQeaatLAANNTQLQARVEMLETERG 444
Cdd:PRK03918   315 RLSRLEEEINGIEERIKELEEKEERLEE-LKKKLKELEKRLEELEERHELYEEAKA----KKEELERLKKRLTGLTPEKL 389

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  445 QQEAKLLAERG-HFEEEKQQLSSLITDLQSSISNLSQAKEELEQA-----------SQAHGARLtaqVASLTSELTTLNA 512
Cdd:PRK03918   390 EKELEELEKAKeEIEEEISKITARIGELKKEIKELKKAIEELKKAkgkcpvcgrelTEEHRKEL---LEEYTAELKRIEK 466

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  513 TIQQQDQELAGLKQQAKEKQAQLAQtlqqqeqasqglrhqvEQLSSSLKQKEQQLKEVAEKqeaTRQDHAQQLATAAEER 592
Cdd:PRK03918   467 ELKEIEEKERKLRKELRELEKVLKK----------------ESELIKLKELAEQLKELEEK---LKKYNLEELEKKAEEY 527

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  593 EASLRERDAALKQLEALEKEkAAKLEILQQQLQVANEARDSaqtsvtqAQREKAELSRKVEELQ-ACVEtarqeqhEAQA 671
Cdd:PRK03918   528 EKLKEKLIKLKGEIKSLKKE-LEKLEELKKKLAELEKKLDE-------LEEELAELLKELEELGfESVE-------ELEE 592

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  672 QVAELE------LQLRSEQQkatEKERVAQEKDQLQEQLQALKESLKVTKGSLEEEKRRaadaLEEQQRCISElkaetrs 745
Cdd:PRK03918   593 RLKELEpfyneyLELKDAEK---ELEREEKELKKLEEELDKAFEELAETEKRLEELRKE----LEELEKKYSE------- 658

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  746 lvEQHKRERKELEEERAGRKGLEARLQQLgEAHQAETEVLRRELAEAMAAQHTAESECEQLVK---EVAAWRERYEDSQQ 822
Cdd:PRK03918   659 --EEYEELREEYLELSRELAGLRAELEEL-EKRREEIKKTLEKLKEELEEREKAKKELEKLEKaleRVEELREKVKKYKA 735


                   ....*.
gi 1370459521  823 EEAQYG 828
Cdd:PRK03918   736 LLKERA 741
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1382-1731 6.32e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 68.04  E-value: 6.32e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1382 REELEQSKQAAGGLRAELLRAQRELgelipLRQKVAEQERTAQQLRAEKASYAEQLSMLKKAHGLLAEENRGLGERanlg 1461
Cdd:COG1196    219 KEELKELEAELLLLKLRELEAELEE-----LEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAE---- 289

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1462 rqflEVELDQAREKYVQELAAvradAETRLAEVQREAQSTARELEVmtakyegakvkvLEERQR-FQEERQKLTAQVEQL 1540
Cdd:COG1196    290 ----EYELLAELARLEQDIAR----LEERRRELEERLEELEEELAE------------LEEELEeLEEELEELEEELEEA 349

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1541 EVFQREQTKQVEELSKKLADSDQASKVQQQKLKAVQAQGGESQQEAQRLQAQLNELQAQLSQKEQAAEHYKLQMEKAKth 1620
Cdd:COG1196    350 EEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELE-- 427

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1621 yDAKKQQNQELQEQLRSLEQLQKENKELRAEAERLGHELQQAGLKTKEAEQTCRHLTAQVRSLEAQVAHADQQLRDLGKF 1700
Cdd:COG1196    428 -EALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGF 506

                          330       340       350
                   ....*....|....*....|....*....|.
gi 1370459521 1701 QVATDALKSREPQAKPQLDLSIDSLDLSCEE 1731
Cdd:COG1196    507 LEGVKAALLLAGLRGLAGAVAVLIGVEAAYE 537
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
276-890 1.48e-10

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 66.86  E-value: 1.48e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  276 KELEELRDKNESLT--MRLHETLKQCQDLKTEKSQMDRKIN--QLSEENGDLSFKLREFASHLQQLQDALNELTEEHSKA 351
Cdd:COG4913    242 EALEDAREQIELLEpiRELAERYAAARERLAELEYLRAALRlwFAQRRLELLEAELEELRAELARLEAELERLEARLDAL 321

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  352 TQEWLEKQAQLekeLSAALQDKKCLEEKNEILQGKLSQLEEHLSQLQDnppqekgevLGDVLQLeTLKQEAATLAANNTQ 431
Cdd:COG4913    322 REELDELEAQI---RGNGGDRLEQLEREIERLERELEERERRRARLEA---------LLAALGL-PLPASAEEFAALRAE 388

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  432 LQARVEMLETERG---QQEAKLLAERGHFEEEKQQLSSLITDLQSSISNLS----QAKEELEQASQA------------- 491
Cdd:COG4913    389 AAALLEALEEELEaleEALAEAEAALRDLRRELRELEAEIASLERRKSNIParllALRDALAEALGLdeaelpfvgelie 468

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  492 ----------------HGARLT--------AQVAS------LTSELTTlnatiqqqdqelaglkqqakEKQAQLAQTLQQ 541
Cdd:COG4913    469 vrpeeerwrgaiervlGGFALTllvppehyAAALRwvnrlhLRGRLVY--------------------ERVRTGLPDPER 528

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  542 QEQASQGLRHQVE----QLSSSLKQkeqqlkEVAEKQEATRQDHAQQLATaaEER----------EASLRERDAALKQLE 607
Cdd:COG4913    529 PRLDPDSLAGKLDfkphPFRAWLEA------ELGRRFDYVCVDSPEELRR--HPRaitragqvkgNGTRHEKDDRRRIRS 600

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  608 A--LEKEKAAKLEILQQQLQVANEARDSAQTSVTQAQREKAELSRKVEELQACVETARQEQ--HEAQAQVAELELQLRSE 683
Cdd:COG4913    601 RyvLGFDNRAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEIdvASAEREIAELEAELERL 680

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  684 QQKATEKERVAQEKDQLQEQLQALKESLKVTKGSLEEEKRRAADALEEQQRCiselkaetrslveQHKRERKELEEERAG 763
Cdd:COG4913    681 DASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDEL-------------QDRLEAAEDLARLEL 747

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  764 RKGLEARLQQLG--EAHQAETEVLRRELAEAMAAQHTAEsecEQLVKEVAAWRERYEDSQQE---EAQYGAMFQEQLMTL 838
Cdd:COG4913    748 RALLEERFAAALgdAVERELRENLEERIDALRARLNRAE---EELERAMRAFNREWPAETADldaDLESLPEYLALLDRL 824

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1370459521  839 KEEcekarqELQEAKEKVAgieshsELQISRQQNELAELHANLARALQQVQE 890
Cdd:COG4913    825 EED------GLPEYEERFK------ELLNENSIEFVADLLSKLRRAIREIKE 864
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
478-985 1.85e-10

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 66.22  E-value: 1.85e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  478 LSQAKEELEQASQAHgarLTAQVASLTSELTTLNATI---QQQDQELAGLKQQAKEKQAQLAQTLQQQEQASQGLRHQVE 554
Cdd:PRK02224   189 LDQLKAQIEEKEEKD---LHERLNGLESELAELDEEIeryEEQREQARETRDEADEVLEEHEERREELETLEAEIEDLRE 265

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  555 QLSSSLKQKEQqLKEVAEKQEATRQDHAQQLATAAEEREASLRERDAALKQLEALEKEKAAKLEILQQQ---LQVANEAR 631
Cdd:PRK02224   266 TIAETEREREE-LAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECrvaAQAHNEEA 344

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  632 DSAQTSVTQAQREKAELSRKVEELQACVETARQEQHEAQAQVAELELQLRSEQQK----ATEKERVAQEKDQLQEQLQAL 707
Cdd:PRK02224   345 ESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERfgdaPVDLGNAEDFLEELREERDEL 424

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  708 KESLKVTKGSLE--EEKRRAADALEEQQRC-----------ISELKAETRSLVEQHKRERKELEEERAgrkGLEARLQQL 774
Cdd:PRK02224   425 REREAELEATLRtaRERVEEAEALLEAGKCpecgqpvegspHVETIEEDRERVEELEAELEDLEEEVE---EVEERLERA 501

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  775 GEAHQAETEV----LRRELAEAMAAQHTAeseceqlvkEVAAWRERYEDSQQEEAQYGAMFQEQlmtlKEECEKARQELQ 850
Cdd:PRK02224   502 EDLVEAEDRIerleERREDLEELIAERRE---------TIEEKRERAEELRERAAELEAEAEEK----REAAAEAEEEAE 568

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  851 EAKEKVAGIESH-SELQISRQQ-NELAELHANLARALQQVQEKEVRAQKLADDLSTLQEKMAATSKEVARLETLVRKAGE 928
Cdd:PRK02224   569 EAREEVAELNSKlAELKERIESlERIRTLLAAIADAEDEIERLREKREALAELNDERRERLAEKRERKRELEAEFDEARI 648

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1370459521  929 QQETASRELVKEPARAGDRQPEWLEEQQGRqfcsTQAALQAMEREAEqmgnELERLR 985
Cdd:PRK02224   649 EEAREDKERAEEYLEQVEEKLDELREERDD----LQAEIGAVENELE----ELEELR 697
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1075-1662 1.05e-09

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 64.17  E-value: 1.05e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1075 AQIKELEELRQTVKQLKEQLakkekehasgsgaqsEAAGRTEPTGPKLEALRAEVSKLEQQCQKQQEQADSLERSLEAER 1154
Cdd:COG4913    232 EHFDDLERAHEALEDAREQI---------------ELLEPIRELAERYAAARERLAELEYLRAALRLWFAQRRLELLEAE 296

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1155 ASRAERDsaLETLQGQLEEKAQELGHSQSALASAQRELAafrtkvQDHSKAEDEWKAQVARGRQEAERKNSLISSLEEEV 1234
Cdd:COG4913    297 LEELRAE--LARLEAELERLEARLDALREELDELEAQIR------GNGGDRLEQLEREIERLERELEERERRRARLEALL 368

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1235 SILNRQVLEKEGESKELKRLVMAESEKSQKLEERLRLLQAETASNSARAAERSSALREEVQSLREEAEKQRVASENLRQE 1314
Cdd:COG4913    369 AALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPARLLALRDA 448

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1315 LTSQAERAE----------ELGQELKAWQEKFfqkEQALSTLQL------EHtstQALVSELLPAKHLcqqLQAEQAAAE 1378
Cdd:COG4913    449 LAEALGLDEaelpfvgeliEVRPEEERWRGAI---ERVLGGFALtllvppEH---YAAALRWVNRLHL---RGRLVYERV 519

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1379 KRHREELEQSKQAAGGLRAELL--------RAQRELGELIPLRqKVAeqerTAQQLRAEKASYAEQlSMLKKAHGLLA-E 1449
Cdd:COG4913    520 RTGLPDPERPRLDPDSLAGKLDfkphpfraWLEAELGRRFDYV-CVD----SPEELRRHPRAITRA-GQVKGNGTRHEkD 593

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1450 ENRGLGERANLGRqfleveldQAREKyVQELAAVRADAETRLAEVQREAQSTARELEVMTAKYEgakvkVLEERQRFQEE 1529
Cdd:COG4913    594 DRRRIRSRYVLGF--------DNRAK-LAALEAELAELEEELAEAEERLEALEAELDALQERRE-----ALQRLAEYSWD 659

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1530 RQKLTAQVEQLEVFQREQtKQVEELSKKLADSDQASKVQQQKLKAVQAQGGESQQEAQRLQAQLNELQAQLSQKEQAAEH 1609
Cdd:COG4913    660 EIDVASAEREIAELEAEL-ERLDASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEA 738

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1370459521 1610 Y-KLQMEKAKTHYDAKKQQNQELQEQLRSLEQLQKENKELRAEAERLGHELQQA 1662
Cdd:COG4913    739 AeDLARLELRALLEERFAAALGDAVERELRENLEERIDALRARLNRAEEELERA 792
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 242-920 1.22e-09

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 63.98  E-value: 1.22e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  242 KLLTEKDAQIAMMQQRI----DRL-ALLNEKQAASPL----EPKELEELRDKNESLTMRLHETLKQCQDLKTE-KSQMDR 311
Cdd:pfam15921  224 KILRELDTEISYLKGRIfpveDQLeALKSESQNKIELllqqHQDRIEQLISEHEVEITGLTEKASSARSQANSiQSQLEI 303

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  312 KINQLSEENGDLSFKLREFASHLQQLQDALNELTEEHSKATQEwLEKQAQL-EKELSAAL-------QDKKCLEEKNEIL 383
Cdd:pfam15921  304 IQEQARNQNSMYMRQLSDLESTVSQLRSELREAKRMYEDKIEE-LEKQLVLaNSELTEARterdqfsQESGNLDDQLQKL 382

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  384 QGKLSQLEEHLSQLQDNPPQEKGEVLGDVLQLETLKQEAATLAANNTQLQARVEMLETE-RGQQEAKLLAERGHfEEEKQ 462
Cdd:pfam15921  383 LADLHKREKELSLEKEQNKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSEcQGQMERQMAAIQGK-NESLE 461

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  463 QLSSLITDLQSSISNLSQAKEEleqasqahgarLTAQVASL-TSELTTLNATIQQQDQELAglkqqakekqaqlaqtlqq 541
Cdd:pfam15921  462 KVSSLTAQLESTKEMLRKVVEE-----------LTAKKMTLeSSERTVSDLTASLQEKERA------------------- 511

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  542 qeqaSQGLRHQVEQLSSSLKQKEQQLKEVaekqeATRQDHAQQLATAAEereaslrerdaALKqLEALEKEKAakLEILQ 621
Cdd:pfam15921  512 ----IEATNAEITKLRSRVDLKLQELQHL-----KNEGDHLRNVQTECE-----------ALK-LQMAEKDKV--IEILR 568

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  622 QQLQ-----VANEARDSAQTSVTQAQREKAELSRKVE--ELQACVETARQEQHEAQAQVAELELQLRSEQQKATEKER-- 692
Cdd:pfam15921  569 QQIEnmtqlVGQHGRTAGAMQVEKAQLEKEINDRRLElqEFKILKDKKDAKIRELEARVSDLELEKVKLVNAGSERLRav 648

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  693 --VAQEKDQLQEQLQALKESLKVTKGSLEEEKRRAADALEEQQRCISELKAETRSLveqhkrerkeleeeragrkglear 770
Cdd:pfam15921  649 kdIKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMETTTNKLKMQLKSA------------------------ 704

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  771 lqqlgeahQAETEVLRRELAEAMAAQHTAESECEQLVKEVAAWReryedSQQEEAQYGAMFQEQLMTlkeECEKARQELQ 850
Cdd:pfam15921  705 --------QSELEQTRNTLKSMEGSDGHAMKVAMGMQKQITAKR-----GQIDALQSKIQFLEEAMT---NANKEKHFLK 768

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  851 EAKEKVAGIESHSELQISRQQNELAELHANLARALQQVQEKEVRAQKLADDLSTLQEKMAATSKEVARLE 920
Cdd:pfam15921  769 EEKNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANMEVALDKASLQFAECQDIIQRQEQESVRLK 838
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
772-1329 2.72e-09

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 62.63  E-value: 2.72e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  772 QQLGEAHQA------ETEVLR--RELAEAMAAQHTAESECEQLVKEVAAWR--ERYEDSQQEEAQygamFQEQLMTLKEE 841
Cdd:COG4913    235 DDLERAHEAledareQIELLEpiRELAERYAAARERLAELEYLRAALRLWFaqRRLELLEAELEE----LRAELARLEAE 310

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  842 CEKARQELQEAKEKVAgieshsELQISRQQN---ELAELHANLARALQQVQEKEVRAQKLADDLSTLQEKMAATSKEVAR 918
Cdd:COG4913    311 LERLEARLDALREELD------ELEAQIRGNggdRLEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAA 384

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  919 LETLVRKAGEQQETASRELVKEPARAGDRqpewlEEQQGRQFCSTQAALQAMEREAEQMGNELERLRAALmesqgQQQEE 998
Cdd:COG4913    385 LRAEAAALLEALEEELEALEEALAEAEAA-----LRDLRRELRELEAEIASLERRKSNIPARLLALRDAL-----AEALG 454

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  999 RGQQEREVA------RLTQERGRAQADLAL-------------EKAARAELE-MRLQNALNEQRVEFATLQEA------- 1051
Cdd:COG4913    455 LDEAELPFVgelievRPEEERWRGAIERVLggfaltllvppehYAAALRWVNrLHLRGRLVYERVRTGLPDPErprldpd 534

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1052 -LAHALTEKEGK-----DQELAklRGLEAAQIKELEELRQT---------VKQLKEQLAKKEKEHASGS---GAQSEAag 1113
Cdd:COG4913    535 sLAGKLDFKPHPfrawlEAELG--RRFDYVCVDSPEELRRHpraitragqVKGNGTRHEKDDRRRIRSRyvlGFDNRA-- 610

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1114 rteptgpKLEALRAEVSKLEQQCQKqqeqADSLERSLEAERASRAERDSALETLQGQLEEkaqelghsQSALASAQRELA 1193
Cdd:COG4913    611 -------KLAALEAELAELEEELAE----AEERLEALEAELDALQERREALQRLAEYSWD--------EIDVASAEREIA 671

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1194 AFRTKvqdhskaedewkaqvargRQEAERKNSLISSLEEEVSILNRQVLEKEGESKELKRLVMAESEKSQKLEERLRLLQ 1273
Cdd:COG4913    672 ELEAE------------------LERLDASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQ 733

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1370459521 1274 AETASNSARAAERSSALREEVQSLREEAEKQRVASENLRQELTSQAERAEELGQEL 1329
Cdd:COG4913    734 DRLEAAEDLARLELRALLEERFAAALGDAVERELRENLEERIDALRARLNRAEEEL 789
MARTX_Nterm NF012221
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...
 406-647 2.73e-09

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.


Pssm-ID: 467957 [Multi-domain]  Cd Length: 1848  Bit Score: 62.93  E-value: 2.73e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  406 GEVLGDVLQLETLKQEAATLAANNTQLQARVEMLetergQQEAKLLAERGHFEEEKQQLSSLITDLQSSISNLSQAKeeL 485
Cdd:NF012221  1528 GYILDNVVATSESSQQADAVSKHAKQDDAAQNAL-----ADKERAEADRQRLEQEKQQQLAAISGSQSQLESTDQNA--L 1600

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  486 EQASQAHGARLTAQVASLTSELTTLNATIQQ---QDQELAGLKQQAKEKQAQLAQTLQQQEQASQGL--RHQVEQLSSSL 560
Cdd:NF012221  1601 ETNGQAQRDAILEESRAVTKELTTLAQGLDAldsQATYAGESGDQWRNPFAGGLLDRVQEQLDDAKKisGKQLADAKQRH 1680

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  561 KQKEQQLKEVAEKQEA--TRQDHAQQLATAAEER---EASLRERDAALKQLEALEKEKAAKLeilqqqlqVANEARDSAQ 635
Cdd:NF012221  1681 VDNQQKVKDAVAKSEAgvAQGEQNQANAEQDIDDakaDAEKRKDDALAKQNEAQQAESDANA--------AANDAQSRGE 1752

                          250
                   ....*....|..
gi 1370459521  636 TSVTQAQREKAE 647
Cdd:NF012221  1753 QDASAAENKANQ 1764
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1060-1665 3.22e-09

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 62.39  E-value: 3.22e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1060 EGKDQELAKLRGLEAAQIKELEELRQTVKQLKEQLAKKEKEHAsgsgaqsEAAGRTEPTGPKLEALRAEVSKLEQQCQKQ 1139
Cdd:PRK03918   161 ENAYKNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELE-------EVLREINEISSELPELREELEKLEKEVKEL 233

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1140 QEQADSLErSLEAERASRAERDSALETLQGQLEEKAQELGHSQSALASAQRELAAFRTKVQDHSKAE---DEWKAQVARG 1216
Cdd:PRK03918   234 EELKEEIE-ELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKEKAEEYIKLSefyEEYLDELREI 312

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1217 RQEAERKNSLISSLEEEVSILNrqvlEKEGESKELKRLVMAESEKSQKLEERLRLLqaetasnsaraaERSSALREEVQS 1296
Cdd:PRK03918   313 EKRLSRLEEEINGIEERIKELE----EKEERLEELKKKLKELEKRLEELEERHELY------------EEAKAKKEELER 376

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1297 LREEAEKQRVasENLRQELTSQAERAEELGQELKAWQEKffqkeqaLSTLQLEHTSTQALVSELLPAKHLC-----QQLQ 1371
Cdd:PRK03918   377 LKKRLTGLTP--EKLEKELEELEKAKEEIEEEISKITAR-------IGELKKEIKELKKAIEELKKAKGKCpvcgrELTE 447

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1372 AEQAAAEKRHREEL---EQSKQAAGGLRAELLRAQRELGELIPLRQKVAEQERTAQQLRAEKASYAE-QLSMLKKAhgll 1447
Cdd:PRK03918   448 EHRKELLEEYTAELkriEKELKEIEEKERKLRKELRELEKVLKKESELIKLKELAEQLKELEEKLKKyNLEELEKK---- 523

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1448 AEENRGLGERAN-LGRQFLEVELDQAREKyvqELAAVRADAETRLAEVQREAQSTARELEVMTAKYEGAKVKVLEERQRF 1526
Cdd:PRK03918   524 AEEYEKLKEKLIkLKGEIKSLKKELEKLE---ELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERLKELEPF 600

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1527 QEERQKLTAQVEQLEVFQREQTKQVEELSKKLADSDQASKVQQQKLKAVQAQGGE-SQQEAQRLQAQLNELQAQLSQKEQ 1605
Cdd:PRK03918   601 YNEYLELKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKySEEEYEELREEYLELSRELAGLRA 680

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1370459521 1606 AAEHYKLQMEKAKTHYD---AKKQQNQELQEQLRSLEQLQKENKELRAEAERLGHELQQAGLK 1665
Cdd:PRK03918   681 ELEELEKRREEIKKTLEklkEELEEREKAKKELEKLEKALERVEELREKVKKYKALLKERALS 743
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
431-928 3.33e-09

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 62.09  E-value: 3.33e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  431 QLQARVEMLETERGQQEAKLLAERGHFEEEKQQLSSLITDLQSSISNLSQAKEELEqasqahgaRLTAQVASLTSELTTL 510
Cdd:COG4717     50 RLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELE--------ELEAELEELREELEKL 121

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  511 NATIQQQD--QELAGLKQQAKEKQAQLAQTLQQQEQASQgLRHQVEQLSSSLKQKEQQLKEVAEKQEATRQDHAQQLATA 588
Cdd:COG4717    122 EKLLQLLPlyQELEALEAELAELPERLEELEERLEELRE-LEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEE 200

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  589 AEEREASLRERDAALKQLEALEKEKAAKLEILQQQLQVANEARDSAQTSVTQAQrekAELSRKVEELQACVETARQEQHE 668
Cdd:COG4717    201 LEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLLLLI---AAALLALLGLGGSLLSLILTIAG 277

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  669 AQAQVAELELQLRSEQQKATEKERVAQEKDQLQEQLQAL-KESLKVTKGSLEEEKRRAADALEEQQRCISELKAETRSLV 747
Cdd:COG4717    278 VLFLVLGLLALLFLLLAREKASLGKEAEELQALPALEELeEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAE 357

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  748 EQHKRERkeleeeragRKGLEARLQQLGEAHQAETEVLRRELAEAMAAQHTAESECEQLVKEVAAwrERYEDSQQEEAQY 827
Cdd:COG4717    358 ELEEELQ---------LEELEQEIAALLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEE--LLGELEELLEALD 426

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  828 GAMFQEQLMTLKEECEKARQELQEAKEKVAGIEshSELQISRQQNELAELHANLARALQQVQEKEVRAQKLADDLSTLQE 907
Cdd:COG4717    427 EEELEEELEELEEELEELEEELEELREELAELE--AELEQLEEDGELAELLQELEELKAELRELAEEWAALKLALELLEE 504

                          490       500
                   ....*....|....*....|.
gi 1370459521  908 KMAATSKEvaRLETLVRKAGE 928
Cdd:COG4717    505 AREEYREE--RLPPVLERASE 523
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
236-682 8.64e-09

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 60.55  E-value: 8.64e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  236 ELAENRKLLTEKDAQIAMMQQRIDRLALLNEKQAASPLEPKELEELRDKNESLTmRLHETLKQCQDLKTEKSQMDRKINQ 315
Cdd:COG4717     72 ELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLL-QLLPLYQELEALEAELAELPERLEE 150

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  316 LSEENGDLSFKLREFASHLQQLQDALNELTEEHSKATQEWLEKQAQLEKELSAALQDKKCLEEKNEILQGKLSQLEEHLS 395
Cdd:COG4717    151 LEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELE 230

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  396 QLQDN-PPQEKGEVLGDVLQLETLKQEAATLAANNTQLQARVEMLETERGQQEAKLLAERGHFEEEKQQLSSLITDLQSS 474
Cdd:COG4717    231 QLENElEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQAL 310

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  475 ISNLSQAKEELEQASQAHGARLTAQVASLTSELTTLnATIQQQDQELAGLKQQAKEKQAQLAQTLQQQEQASQGLrhqvE 554
Cdd:COG4717    311 PALEELEEEELEELLAALGLPPDLSPEELLELLDRI-EELQELLREAEELEEELQLEELEQEIAALLAEAGVEDE----E 385

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  555 QLSSSLKQKEQQLKEVAEKQEATRQdhaqqLATAAEEREASLRERDaalkqlealekekaakLEILQQQLQVANEARDSA 634
Cdd:COG4717    386 ELRAALEQAEEYQELKEELEELEEQ-----LEELLGELEELLEALD----------------EEELEEELEELEEELEEL 444

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|
gi 1370459521  635 QTSVTQAQREKAELSRKVEEL--QACVETARQEQHEAQAQVAELELQLRS 682
Cdd:COG4717    445 EEELEELREELAELEAELEQLeeDGELAELLQELEELKAELRELAEEWAA 494
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1008-1331 1.27e-08

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 60.44  E-value: 1.27e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1008 RLTQERGRAQADLALEKAARAELEMRLQnALNEQRVEFATLQEALAHALTEKEGKDQELAKLR----------------- 1070
Cdd:PRK02224   224 RYEEQREQARETRDEADEVLEEHEERRE-ELETLEAEIEDLRETIAETEREREELAEEVRDLRerleeleeerddllaea 302

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1071 GLEAAQIKELEELRQTVKQLKEQLAKKEKEHASGSGAQSEAAgrteptgpklEALRAEVSKLEQQCQKQQEQADSLERSL 1150
Cdd:PRK02224   303 GLDDADAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEA----------ESLREDADDLEERAEELREEAAELESEL 372

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1151 EAERASRAERDSALETLQGQLEEKAQ-------ELGHSQSALASAQRELAAFRTKVQDHSKAEDEWKAQVARGRQ----- 1218
Cdd:PRK02224   373 EEAREAVEDRREEIEELEEEIEELRErfgdapvDLGNAEDFLEELREERDELREREAELEATLRTARERVEEAEAlleag 452

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1219 ----------------EAERKNSLISSLEEEVSILNRQVLEKEGESKELKRLVMAESEKSQKLEERLRL--LQAETASNS 1280
Cdd:PRK02224   453 kcpecgqpvegsphveTIEEDRERVEELEAELEDLEEEVEEVEERLERAEDLVEAEDRIERLEERREDLeeLIAERRETI 532

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1370459521 1281 ARAAERSSALREEVQSLREEAEKQRVASENLRQELTSQAERAEELGQELKA 1331
Cdd:PRK02224   533 EEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAE 583
MAD pfam05557
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ...
 215-745 1.33e-08

Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.


Pssm-ID: 461677 [Multi-domain]  Cd Length: 660  Bit Score: 60.14  E-value: 1.33e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  215 QMRRLKKQLADE-RSNRDELELELAENRKLLTEKDAQIAMMQQRIDRLALLNEKQAASPLEPKELEELRDKN-ESLTMRL 292
Cdd:pfam05557   13 QLQNEKKQMELEhKRARIELEKKASALKRQLDRESDRNQELQKRIRLLEKREAEAEEALREQAELNRLKKKYlEALNKKL 92

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  293 HETLKQCQDLKTEKSQMDRKINQLSEENGDLSFKLREFASHLQQLQDALNELTEEHSKATQEWLEKQAQLeKELSAALQD 372
Cdd:pfam05557   93 NEKESQLADAREVISCLKNELSELRRQIQRAELELQSTNSELEELQERLDLLKAKASEAEQLRQNLEKQQ-SSLAEAEQR 171

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  373 KKCLEEKNeilqgklsQLEEHLSQLQDNPPQEKGEVLGDVLQLETLKQEAA---TLAANNTQLQARVEMLETERGQQE-- 447
Cdd:pfam05557  172 IKELEFEI--------QSQEQDSEIVKNSKSELARIPELEKELERLREHNKhlnENIENKLLLKEEVEDLKRKLEREEky 243

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  448 ----AKLLAERGHFEEEKQQLSSLITDLQSSISNLSQAKEELEQASQAHGArLTAQVASLTSELTTLNATIQQQDQELAG 523
Cdd:pfam05557  244 reeaATLELEKEKLEQELQSWVKLAQDTGLNLRSPEDLSRRIEQLQQREIV-LKEENSSLTSSARQLEKARRELEQELAQ 322

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  524 LKQQAKEKQAQLAQTLQQQEQASQ----------GLRHQVEQLSSSLKQKE--QQLKEVAEKQEATRQDHAQQLATAAEE 591
Cdd:pfam05557  323 YLKKIEDLNKKLKRHKALVRRLQRrvllltkerdGYRAILESYDKELTMSNysPQLLERIEEAEDMTQKMQAHNEEMEAQ 402

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  592 REASLRERDAALKQLEALEKEkaakLEILQQQLQVANeardsaqtsVTQAQREKAELSRKVEELQACVETARQEQHEAQA 671
Cdd:pfam05557  403 LSVAEEELGGYKQQAQTLERE----LQALRQQESLAD---------PSYSKEEVDSLRRKLETLELERQRLREQKNELEM 469

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  672 QVAELELQLRSEQQK-----------ATEKERVAQEKDQLQEQLQALKESLKVTKGSLEEEKRRAADALEEQQRCISELK 740
Cdd:pfam05557  470 ELERRCLQGDYDPKKtkvlhlsmnpaAEAYQQRKNQLEKLQAEIERLKRLLKKLEDDLEQVLRLPETTSTMNFKEVLDLR 549


                   ....*
gi 1370459521  741 AETRS 745
Cdd:pfam05557  550 KELES 554
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 220-1051 1.79e-08

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 59.99  E-value: 1.79e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  220 KKQLADERSNRDELELELAENRKLLTEKDAQIAMMQQRIDRLALlnEKQAASPLEPKELEELRDKNESLTMRLHETLKQC 299
Cdd:pfam02463  180 EETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEE--EYLLYLDYLKLNEERIDLLQELLRDEQEEIESSK 257

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  300 QDLKTEKSQMDRKINQLSEENGDLSFKLREFASH------LQQLQDALNELTEEHSKATQEWLEKQAQLEKELSAALQDK 373
Cdd:pfam02463  258 QEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLakeeeeLKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEI 337

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  374 KCLEEKNEILQGKLSQLEEHLSQLQDNppQEKGEVLGDVLQLETLKQEAATLAANNTQLQARVEMLETERGQQEAKllae 453
Cdd:pfam02463  338 EELEKELKELEIKREAEEEEEEELEKL--QEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLL---- 411

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  454 rghfeEEKQQLSSLITDLQSSISNLSQAKEELEQASQAHGARLTAQVASLTSELTTLNATIQQQDQELAGLKQQAKEKQA 533
Cdd:pfam02463  412 -----ELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQL 486

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  534 QLAQTLQQQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEATRQDHAQQLATAAEEREASLRERDAALKQLEALEKEK 613
Cdd:pfam02463  487 ELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKL 566

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  614 AAKLEILQQQLQVANEARDSAQTSVTQAQREKAELSRKVEELQACVETARqeQHEAQAQVAELELQLRSEQQKATEKERV 693
Cdd:pfam02463  567 VRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEAD--EDDKRAKVVEGILKDTELTKLKESAKAK 644

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  694 AQEKDQLQEQLQALKESLKVTKGSLEEEKRRAADALEEQQRCISELKAETRS-----LVEQHKRERKELEEERAGRKGLE 768
Cdd:pfam02463  645 ESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRrqleiKKKEQREKEELKKLKLEAEELLA 724

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  769 ARLQQLGEAHQAETEVLRRELAEAMA----AQHTAESECEQLVKEVAAWRERYEDSQQEEAQYGAMFQEQLMTLKEECEK 844
Cdd:pfam02463  725 DRVQEAQDKINEELKLLKQKIDEEEEeeekSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELR 804

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  845 ARQELQEAKEKVAGIESHSELQISRQQNELAELHANLAralqqvqEKEVRAQKLADDLSTLQEKMAATSKEVARLETLVR 924
Cdd:pfam02463  805 ALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALEL-------KEEQKLEKLAEEELERLEEEITKEELLQELLLKEE 877

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  925 KAGEQQETASRELVKEPARAGDRQPEWLEEQQGRQFCSTQAALQAMEREAEQMGNELErlraalMESQGQQQEERGQQER 1004
Cdd:pfam02463  878 ELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEE------EPEELLLEEADEKEKE 951

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|....*..
gi 1370459521 1005 EVARLTQERGRAQADLALEKAARAELEMRLQNALNEQRVEFATLQEA 1051
Cdd:pfam02463  952 ENNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKE 998
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 327-1112 2.09e-08

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 59.75  E-value: 2.09e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  327 LREFASHLQQLQDALNELTEEHSKatQEWLEKQAQLEkeLSAALQDKKCLEEKNEILQGKLSQLEEHL-SQLQDNppqek 405
Cdd:pfam15921   80 LEEYSHQVKDLQRRLNESNELHEK--QKFYLRQSVID--LQTKLQEMQMERDAMADIRRRESQSQEDLrNQLQNT----- 150

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  406 gevlgdVLQLETLKQ-EAATLAANNTQLQARVEMLETERG-------------QQEAKLLAERG-----HFEEEKQQLSS 466
Cdd:pfam15921  151 ------VHELEAAKClKEDMLEDSNTQIEQLRKMMLSHEGvlqeirsilvdfeEASGKKIYEHDsmstmHFRSLGSAISK 224

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  467 LITDLQSSISNL---------------SQAKEELEQASQAHGARLTAQVASLTSELTTLNatiqqqdQELAGLKQQAKEK 531
Cdd:pfam15921  225 ILRELDTEISYLkgrifpvedqlealkSESQNKIELLLQQHQDRIEQLISEHEVEITGLT-------EKASSARSQANSI 297

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  532 QAQLAQTLQQQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEATRQDHAQQLATAAEEREASLRERDAALKQLEALE- 610
Cdd:pfam15921  298 QSQLEIIQEQARNQNSMYMRQLSDLESTVSQLRSELREAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQESGNLDd 377

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  611 --KEKAAKLEILQQQLQVANEA------RDSAQT-SVTQAQREKAELSRKVEELQACVETARQEQHeaqaqvAELELQLR 681
Cdd:pfam15921  378 qlQKLLADLHKREKELSLEKEQnkrlwdRDTGNSiTIDHLRRELDDRNMEVQRLEALLKAMKSECQ------GQMERQMA 451

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  682 SEQQKATEKERVAQEKDQLQ---EQLQALKESLKVTKGSLEEEKRRAAD---ALEEQQRCISELKAETRSLveqhkrerk 755
Cdd:pfam15921  452 AIQGKNESLEKVSSLTAQLEstkEMLRKVVEELTAKKMTLESSERTVSDltaSLQEKERAIEATNAEITKL--------- 522

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  756 eleeeragRKGLEARLQQLGEAH---------QAETEVLRRELAEAMAAQHTAESECEQLVKEVAAWRERYEDSQQEEAQ 826
Cdd:pfam15921  523 --------RSRVDLKLQELQHLKnegdhlrnvQTECEALKLQMAEKDKVIEILRQQIENMTQLVGQHGRTAGAMQVEKAQ 594

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  827 YGAMFQEQLMTLKE---ECEKARQELQEAKEKVAGIESHSELQI---SRQQNELAELHANLARALQQVQEKEVRAQKLAD 900
Cdd:pfam15921  595 LEKEINDRRLELQEfkiLKDKKDAKIRELEARVSDLELEKVKLVnagSERLRAVKDIKQERDQLLNEVKTSRNELNSLSE 674

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  901 DLSTLQEKMAATSKEvarLETLVRKAGEQQETASRELvkEPARAGDRQPEWLEEQQGRQFCSTQAALQAMEREAEQMGNE 980
Cdd:pfam15921  675 DYEVLKRNFRNKSEE---METTTNKLKMQLKSAQSEL--EQTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSK 749

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  981 LERLRAALMESQGQQ---QEERGQQEREVARLTQERGRAQADLALEKAARAELEMRLQN---ALNEQRVEFATLQEALah 1054
Cdd:pfam15921  750 IQFLEEAMTNANKEKhflKEEKNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANmevALDKASLQFAECQDII-- 827

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1370459521 1055 altekEGKDQELAKLRGLEAAQIKELE----ELRQTVKQLKEQLAKKEKEHASGSGAQSEAA 1112
Cdd:pfam15921  828 -----QRQEQESVRLKLQHTLDVKELQgpgyTSNSSMKPRLLQPASFTRTHSNVPSSQSTAS 884
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 547-749 2.52e-08

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 58.62  E-value: 2.52e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  547 QGLRHQVEQLSSSLKQKEQQLKEVAEKQEATRQ---DHAQQLATAAEEREASLRERDAALKQLEALEKEKAAKLEILQQQ 623
Cdd:COG4942     30 EQLQQEIAELEKELAALKKEEKALLKQLAALERriaALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELAEL 109

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  624 LQVANEARDSAQTSVTQAQREKAELSRKVEELQACVETARQEQHEAQAQVAELELQLRSEQQKATEKERVAQEKDQLQEQ 703
Cdd:COG4942    110 LRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAELEEERAA 189

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*.
gi 1370459521  704 LQALKESLKVTKGSLEEEKRRAADALEEQQRCISELKAETRSLVEQ 749
Cdd:COG4942    190 LEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAE 235
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1239-1707 2.55e-08

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 59.54  E-value: 2.55e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1239 RQVLEKEGESKELKRLVMAESEKSQKLEERLRLLQAE-TASNSARAAERSSALREEVQSLREEAEKQRVASENLRQELTS 1317
Cdd:COG4913    241 HEALEDAREQIELLEPIRELAERYAAARERLAELEYLrAALRLWFAQRRLELLEAELEELRAELARLEAELERLEARLDA 320

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1318 QAERAEEL--------GQELKAWQEKFFQKEQALSTLQLEHTSTQALVSELlpakhlcQQLQAEQAAAEKRHREELEQSK 1389
Cdd:COG4913    321 LREELDELeaqirgngGDRLEQLEREIERLERELEERERRRARLEALLAAL-------GLPLPASAEEFAALRAEAAALL 393

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1390 QAAGGLRAELLRAQRELG-ELIPLRQKVAEQERTAQQLRAEKASYAEQL----SMLKKAHGLLAEENRGLGEranlgrqF 1464
Cdd:COG4913    394 EALEEELEALEEALAEAEaALRDLRRELRELEAEIASLERRKSNIPARLlalrDALAEALGLDEAELPFVGE-------L 466

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1465 LEVELDQAR--------------------EKYVQELAAVRA----------DAETRLAEVQR---EAQSTARELEVMTAK 1511
Cdd:COG4913    467 IEVRPEEERwrgaiervlggfaltllvppEHYAAALRWVNRlhlrgrlvyeRVRTGLPDPERprlDPDSLAGKLDFKPHP 546

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1512 YEGAKVKVLEERQRFqeerqkltAQVEQLEVFQRE--------QTKQVEELSKKLADSDQASKVQ-----QQKLKAVQAQ 1578
Cdd:COG4913    547 FRAWLEAELGRRFDY--------VCVDSPEELRRHpraitragQVKGNGTRHEKDDRRRIRSRYVlgfdnRAKLAALEAE 618

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1579 GGESQQEAQRLQAQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQN--QELQEQLRSLEQLQKENKELRAEAERLG 1656
Cdd:COG4913    619 LAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEIDVASAEReiAELEAELERLDASSDDLAALEEQLEELE 698

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1370459521 1657 HELQQAGLKTKEAEQTCRHLTAQVRSLEAQVAHADQQLRDLGKFQVATDAL 1707
Cdd:COG4913    699 AELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRA 749
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
662-1192 2.97e-08

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 59.16  E-value: 2.97e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  662 ARQEQHEAQAQVAELElQLRSEQQKATEKERVAQEKDQLQEQLQALKESLKVTKG-----SLEEEKRRAADALEEQQRCI 736
Cdd:COG4913    240 AHEALEDAREQIELLE-PIRELAERYAAARERLAELEYLRAALRLWFAQRRLELLeaeleELRAELARLEAELERLEARL 318

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  737 SELKAETRSLVEQHkrerkeleeerAGRKGleARLQQLgeahQAETEVLRRELAEAMAAQHTAESECEQLVKEVAAWRER 816
Cdd:COG4913    319 DALREELDELEAQI-----------RGNGG--DRLEQL----EREIERLERELEERERRRARLEALLAALGLPLPASAEE 381

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  817 YEDSQQEEAQYGAMFQEQLMTLKEECEKARQELQEAKEKVAGIEshSELQISRQQN-----ELAELHANLARALQ----- 886
Cdd:COG4913    382 FAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELE--AEIASLERRKsnipaRLLALRDALAEALGldeae 459

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  887 --------QVQEKE-------------------------------VRAQKLADDLSTLQEKMAATSKEVARLE--TLVRK 925
Cdd:COG4913    460 lpfvgeliEVRPEEerwrgaiervlggfaltllvppehyaaalrwVNRLHLRGRLVYERVRTGLPDPERPRLDpdSLAGK 539

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  926 ageqqetasreLVKEPARAGDrqpeWLEEQQGRQF----CSTQAALQAMER---EAEQMGNELERLRAALMESQGQQQEE 998
Cdd:COG4913    540 -----------LDFKPHPFRA----WLEAELGRRFdyvcVDSPEELRRHPRaitRAGQVKGNGTRHEKDDRRRIRSRYVL 604

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  999 RGQQEREVARLTQERGRAQADLALEKAARAELEmRLQNALNEQRVEFATLQEaLAHALTEKEGKDQELAKLRgleaAQIK 1078
Cdd:COG4913    605 GFDNRAKLAALEAELAELEEELAEAEERLEALE-AELDALQERREALQRLAE-YSWDEIDVASAEREIAELE----AELE 678

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1079 ELEELRQTVKQLKEQLAKKEKEHASGSGAQSEAAGRTEPTGPKLEALRAEVSKLEQQCQKQQEQADSLERSLEAERASRA 1158
Cdd:COG4913    679 RLDASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAA 758

                          570       580       590
                   ....*....|....*....|....*....|....
gi 1370459521 1159 ERDSALETLQGQLEEKAQELghsQSALASAQREL 1192
Cdd:COG4913    759 LGDAVERELRENLEERIDAL---RARLNRAEEEL 789
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
215-746 7.96e-08

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 57.74  E-value: 7.96e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  215 QMRRLKKQLADERSNRDELELELAENRklltEKDAQIAMMQQRIDRLallNEKQAASPlepKELEELRDKNESLTMRLHE 294
Cdd:PRK02224   221 EIERYEEQREQARETRDEADEVLEEHE----ERREELETLEAEIEDL---RETIAETE---REREELAEEVRDLRERLEE 290

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  295 TLKQCQDLKTEKSQMDRKINQLSEENGDLSFKLREFASHLQQLQDALNELTEEHSKAT----------QEWLEKQAQLEK 364
Cdd:PRK02224   291 LEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAESLRedaddleeraEELREEAAELES 370

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  365 ELSAALQDKKCLEEKNEILQGKLSQLEE----------HLSQLQDNPPQEKGEVLGDVLQLETLKQEAATLAANNTQLQA 434
Cdd:PRK02224   371 ELEEAREAVEDRREEIEELEEEIEELRErfgdapvdlgNAEDFLEELREERDELREREAELEATLRTARERVEEAEALLE 450

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  435 RVEMLETERGQQEAKLLAERGHFEEEKQQLSSLITDLQSSISNLSQAKEELEQASQAHgarltAQVASLTSELTTLNATI 514
Cdd:PRK02224   451 AGKCPECGQPVEGSPHVETIEEDRERVEELEAELEDLEEEVEEVEERLERAEDLVEAE-----DRIERLEERREDLEELI 525

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  515 QQQDQELAGLKQQAKEkqaqlaqtlqqqeqasqgLRHQVEQLSSSLKQKEqqlkEVAEKQEATRQDHAQQLATAAEEREa 594
Cdd:PRK02224   526 AERRETIEEKRERAEE------------------LRERAAELEAEAEEKR----EAAAEAEEEAEEAREEVAELNSKLA- 582

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  595 slrERDAALKQLEALEkEKAAKLEILQQQLQVANEARDSAQTSVTQAQREKAELSRKVEELQACVETARQEQHEAQAQVA 674
Cdd:PRK02224   583 ---ELKERIESLERIR-TLLAAIADAEDEIERLREKREALAELNDERRERLAEKRERKRELEAEFDEARIEEAREDKERA 658

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1370459521  675 ElelqlrSEQQKATEK-ERVAQEKDQLQEQLQALKESLKvtkgSLEEEKRRaADALEEQQRCISELKAETRSL 746
Cdd:PRK02224   659 E------EYLEQVEEKlDELREERDDLQAEIGAVENELE----ELEELRER-REALENRVEALEALYDEAEEL 720
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 866-1102 1.24e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 56.31  E-value: 1.24e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  866 QISRQQNELAELHANLARALQQVQEKEVRAQKLADDLSTLQEKMAATSKEVARLETLVRKAGEQQETASRELVKeparag 945
Cdd:COG4942     21 AAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAE------ 94

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  946 drqpewLEEQQGRQfcstQAALQAMEREAEQMGneleRLRAALMESQGQQQEERGQQEREVARLTQERGRAQADLALEKA 1025
Cdd:COG4942     95 ------LRAELEAQ----KEELAELLRALYRLG----RQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLA 160

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1370459521 1026 ARAELEMRLQNALNEQRVEFATLQEALAHALTEKEGKDQELAKLRGLEAAQIKELEELRQTVKQLKEQLAKKEKEHA 1102
Cdd:COG4942    161 ELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAA 237
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 215-806 1.25e-07

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 57.27  E-value: 1.25e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  215 QMRRLKKQLADERSNRDELELELAENRklltekdaqiammQQRIDRLALLNEKQAASPLEPKELEELRDKNESLTMRLHE 294
Cdd:COG3096    537 LLEEFCQRIGQQLDAAEELEELLAELE-------------AQLEELEEQAAEAVEQRSELRQQLEQLRARIKELAARAPA 603

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  295 TLKqcqdlkteksqMDRKINQLSEENGDLSFKLREFASHLQQLQDALNELT--EEHSKATQEWLEKQA------------ 360
Cdd:COG3096    604 WLA-----------AQDALERLREQSGEALADSQEVTAAMQQLLEREREATveRDELAARKQALESQIerlsqpggaedp 672

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  361 -------QLEKELSAALQDKKCLEE-----------KNEILQGKLSQLEEHLSQLQDNPPQ----EKGEVLGDVLQLETL 418
Cdd:COG3096    673 rllalaeRLGGVLLSEIYDDVTLEDapyfsalygpaRHAIVVPDLSAVKEQLAGLEDCPEDlyliEGDPDSFDDSVFDAE 752

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  419 KQEAATLAANNtQLQARVEMLETE-------RGQQEAKLLAERghfEEEKQQLSSLITDLQSsISNLSQAKEEL--EQAS 489
Cdd:COG3096    753 ELEDAVVVKLS-DRQWRYSRFPEVplfgraaREKRLEELRAER---DELAEQYAKASFDVQK-LQRLHQAFSQFvgGHLA 827

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  490 QAHG-------ARLTAQVASLTSELTTLNATIQQQDQELAGLKQQ----AKEKQAQLAQTLQQQEQASQGLRHQVEQLSS 558
Cdd:COG3096    828 VAFApdpeaelAALRQRRSELERELAQHRAQEQQLRQQLDQLKEQlqllNKLLPQANLLADETLADRLEELREELDAAQE 907

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  559 S---LKQKEQQLKEVAEKQEATRQDHAQ--QLATAAEEREASLRERDA---ALKQL------------EALEKEKAAKLE 618
Cdd:COG3096    908 AqafIQQHGKALAQLEPLVAVLQSDPEQfeQLQADYLQAKEQQRRLKQqifALSEVvqrrphfsyedaVGLLGENSDLNE 987

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  619 ILQQQLQVANEARDSAQTSVTQAQREKAELSRKVEELQACVETARQEQHEAQAQVAELELQLRSEQQkatekERVAQEKD 698
Cdd:COG3096    988 KLRARLEQAEEARREAREQLRQAQAQYSQYNQVLASLKSSRDAKQQTLQELEQELEELGVQADAEAE-----ERARIRRD 1062

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  699 QLQEQLQAL---KESLKVTKGSLEEEKRRAADALEEQQRcisELKAEtRSLVEQHKRERKELEEERAGRkGLEARLQQLG 775
Cdd:COG3096   1063 ELHEELSQNrsrRSQLEKQLTRCEAEMDSLQKRLRKAER---DYKQE-REQVVQAKAGWCAVLRLARDN-DVERRLHRRE 1137

                          650       660       670
                   ....*....|....*....|....*....|.
gi 1370459521  776 EAHQaETEVLRRELAEAMAAQHTAESECEQL 806
Cdd:COG3096   1138 LAYL-SADELRSMSDKALGALRLAVADNEHL 1167
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1076-1660 1.68e-07

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 56.59  E-value: 1.68e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1076 QIKELEELRQTVKQLK---EQLAKKEKEHASGSGAQSEAAGRTEPTGpKLEALRAEVSKLEqqcqkqqeqaDSLERSLEA 1152
Cdd:PRK02224   160 QLGKLEEYRERASDARlgvERVLSDQRGSLDQLKAQIEEKEEKDLHE-RLNGLESELAELD----------EEIERYEEQ 228

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1153 ERASRAERDSALETL------QGQLEEKAQELGHSQSALASAQRELAAFRTKVQDHSKAEDEWKAQVARGRQEAERKNSL 1226
Cdd:PRK02224   229 REQARETRDEADEVLeeheerREELETLEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDAD 308

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1227 ISSLEEEVSILNRQvlekegeskelkrlvmaESEKSQKLEERlRLLQAETASNSARAAERSSALREEVQSLREEAEKQRV 1306
Cdd:PRK02224   309 AEAVEARREELEDR-----------------DEELRDRLEEC-RVAAQAHNEEAESLREDADDLEERAEELREEAAELES 370

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1307 ASENLRQELTSQAERAEELGQELKAWQEKFFQKEQALSTLQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKRHREELE 1386
Cdd:PRK02224   371 ELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAELEATLRTARERVEEAEALLE 450

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1387 QSKQAAGGLRAELLRAQRELGELiplRQKVAEQERTAQQLRAEKASYAEQLSMLKKAHGLLAEENRGLGERANLGRQFLE 1466
Cdd:PRK02224   451 AGKCPECGQPVEGSPHVETIEED---RERVEELEAELEDLEEEVEEVEERLERAEDLVEAEDRIERLEERREDLEELIAE 527

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1467 VE--LDQAREKyVQELAAVRADAETRlAEVQREAQSTARElevmtakyegAKVKVLEERQRFQEERQKLTAQVEQLEvfq 1544
Cdd:PRK02224   528 RRetIEEKRER-AEELRERAAELEAE-AEEKREAAAEAEE----------EAEEAREEVAELNSKLAELKERIESLE--- 592

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1545 reqtkQVEELSKKLADSDQASKVQQQKLKAVQAQGGESQQEAQRLQAQLNELQA--------QLSQKEQAAEHYklqMEK 1616
Cdd:PRK02224   593 -----RIRTLLAAIADAEDEIERLREKREALAELNDERRERLAEKRERKRELEAefdearieEAREDKERAEEY---LEQ 664

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....
gi 1370459521 1617 AKTHYDAKKQQNQELQEQLRSLEQLQKENKELRAEAERLGHELQ 1660
Cdd:PRK02224   665 VEEKLDELREERDDLQAEIGAVENELEELEELRERREALENRVE 708
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1122-1612 1.92e-07

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 56.31  E-value: 1.92e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1122 LEALRAEVSKLEQQCQKQQEQADSLERSLEAERASRAERDSALETLQGQLEEKAQELghsqsalASAQRELAAFRTKVQD 1201
Cdd:COG4717     48 LERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEEL-------EELEAELEELREELEK 120

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1202 HSKAEDEWKAqvargRQEAERKNSLISSLEEEVSILNRQVLEKEGESKELKRLVMAESEKSQKLEERLRLLQAETASNSA 1281
Cdd:COG4717    121 LEKLLQLLPL-----YQELEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQ 195

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1282 RAAERSSALREEVQSLREEAEKQRVASENLRQELTSQAERAEELGQELKAWQEKFFQKEQA-LSTLQLEHTSTQALVSEL 1360
Cdd:COG4717    196 DLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLLLLIAAaLLALLGLGGSLLSLILTI 275

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1361 LPAKHLCQQLQAEQAAAEKRHREELEQSKQAAGGLRAellraqrelgeliplrQKVAEQERTAQQLRAEKASYAEQLSML 1440
Cdd:COG4717    276 AGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPA----------------LEELEEEELEELLAALGLPPDLSPEEL 339

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1441 KKAHGLLAEENRGLGERANLGRQFLEVELDQAREKYVQELAAVRADAETRLAEVQREAQSTARELEVMTAKYEGAKVKVL 1520
Cdd:COG4717    340 LELLDRIEELQELLREAEELEEELQLEELEQEIAALLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGELE 419

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1521 EERQRFQEERqkLTAQVEQLEVFQREQTKQVEELSKKLADsdqaskvQQQKLKAVqaqggESQQEAQRLQAQLNELQAQL 1600
Cdd:COG4717    420 ELLEALDEEE--LEEELEELEEELEELEEELEELREELAE-------LEAELEQL-----EEDGELAELLQELEELKAEL 485

                          490
                   ....*....|..
gi 1370459521 1601 SQKEQAAEHYKL 1612
Cdd:COG4717    486 RELAEEWAALKL 497
PRK11281 PRK11281
mechanosensitive channel MscK;
334-643 2.14e-07

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 56.46  E-value: 2.14e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  334 LQQLQDALN--ELTEEHSKATQEWLEKQAQLekelsaaLQDKKCLEEKNEILQGKLSQLEEHLSQLQDNppqekgevlgd 411
Cdd:PRK11281    41 VQAQLDALNkqKLLEAEDKLVQQDLEQTLAL-------LDKIDRQKEETEQLKQQLAQAPAKLRQAQAE----------- 102

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  412 vlqLETLKQEAATLAA------NNTQLQARVEMLETERGQQEAKLLAERGhfeeekqQLSSLITDL---QSSISNLSQAK 482
Cdd:PRK11281   103 ---LEALKDDNDEETRetlstlSLRQLESRLAQTLDQLQNAQNDLAEYNS-------QLVSLQTQPeraQAALYANSQRL 172

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  483 EELEQ---ASQAHGARLTA-QVASLTSELTTLNATIQQQDQELAG-------LKQQAKEKqaqlaqtlqqqEQASQGLRH 551
Cdd:PRK11281   173 QQIRNllkGGKVGGKALRPsQRVLLQAEQALLNAQNDLQRKSLEGntqlqdlLQKQRDYL-----------TARIQRLEH 241

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  552 QVEQL-----SSSLKQKEQQLKEVAEKQEATRQDHAQQLATaaeEREASLRERDAALKQLEALEkekaaklEILQQQLQV 626
Cdd:PRK11281   242 QLQLLqeainSKRLTLSEKTVQEAQSQDEAARIQANPLVAQ---ELEINLQLSQRLLKATEKLN-------TLTQQNLRV 311

                          330
                   ....*....|....*..
gi 1370459521  627 ANEArDSAqtsvTQAQR 643
Cdd:PRK11281   312 KNWL-DRL----TQSER 323
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
645-1309 2.37e-07

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 56.23  E-value: 2.37e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  645 KAELSRKVEELQACVETARQEQHEAQAQVAELELQLRSEQQKATEKERVAQEKDQLQEQLQALKE------SLKVTKGSL 718
Cdd:PRK03918   171 IKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEElkeeieELEKELESL 250

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  719 EEEKRRAADALEEQQRCISELKAETRSLVEQhkrerkeleeeragrkglEARLQQLgEAHQAETEVLRRELAEAMAAQHT 798
Cdd:PRK03918   251 EGSKRKLEEKIRELEERIEELKKEIEELEEK------------------VKELKEL-KEKAEEYIKLSEFYEEYLDELRE 311

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  799 AESECEQLVKEVAAWRERYEDSQQEEAQYGAMFQEQLMTLK--EECEKARQELQEAKEKVAGIESHSELQISRQQNELAE 876
Cdd:PRK03918   312 IEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKrlEELEERHELYEEAKAKKEELERLKKRLTGLTPEKLEK 391

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  877 lhanlaralqQVQEKEVRAQKLADDLSTLQEKMAATSKEVARLETLV---RKAGEQQETASRELVkeparagdrqpewlE 953
Cdd:PRK03918   392 ----------ELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIeelKKAKGKCPVCGRELT--------------E 447

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  954 EQQGRQFCSTQAALQAMEREAEQMGNELERLRAALMESQGqqqeergqqerevARLTQERGRAQADLALE-KAARAELEM 1032
Cdd:PRK03918   448 EHRKELLEEYTAELKRIEKELKEIEEKERKLRKELRELEK-------------VLKKESELIKLKELAEQlKELEEKLKK 514

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1033 RLQNALNEQRVEFATLQEALAHALTEKEGKDQELAKLRGLEAAQIKELEELRQTVKQLKEQLAKKEKEHASGSGAQSEAA 1112
Cdd:PRK03918   515 YNLEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERL 594

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1113 GRTEPTGPKLEALRAEVSKLEQQCQKQqeqaDSLERSLEAERASRAERDSALETLQGQLEEKAQELghsqsalasaqrel 1192
Cdd:PRK03918   595 KELEPFYNEYLELKDAEKELEREEKEL----KKLEEELDKAFEELAETEKRLEELRKELEELEKKY-------------- 656

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1193 aafrtkvqdhskAEDEWKaqvaRGRQEAERKNSLISSLEEEVSILNRQVLEKEGESKELKRlvmaESEKSQKLEERLRLL 1272
Cdd:PRK03918   657 ------------SEEEYE----ELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKE----ELEEREKAKKELEKL 716

                          650       660       670       680
                   ....*....|....*....|....*....|....*....|...
gi 1370459521 1273 QaetasnsaRAAERSSALREEVQSLREEAEK------QRVASE 1309
Cdd:PRK03918   717 E--------KALERVEELREKVKKYKALLKEralskvGEIASE 751
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 314-983 2.71e-07

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 56.11  E-value: 2.71e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  314 NQLSEENgdlsFKLREFASHLQQLQDALNELTEEHSKATqEWLEK---QAQLEKELSAALQDKKCLEEKNEILQGKLSQL 390
Cdd:COG3096    299 RQLAEEQ----YRLVEMARELEELSARESDLEQDYQAAS-DHLNLvqtALRQQEKIERYQEDLEELTERLEEQEEVVEEA 373

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  391 EEHLSQLQDNPPQEKGEVLGDVLQLETLKQEAATLAANNTQLQARVEMLETERGQ-QEAKLLAER-----GHFEEEKQQL 464
Cdd:COG3096    374 AEQLAEAEARLEAAEEEVDSLKSQLADYQQALDVQQTRAIQYQQAVQALEKARALcGLPDLTPENaedylAAFRAKEQQA 453

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  465 SSLITDLQSSISNLSQAKEELEQASQA----HGARLTAQVASLTSELTTLNATIQQQDQELAGLKQQAKEkqaqlaqtLQ 540
Cdd:COG3096    454 TEEVLELEQKLSVADAARRQFEKAYELvckiAGEVERSQAWQTARELLRRYRSQQALAQRLQQLRAQLAE--------LE 525

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  541 QQEQASQGLRHQVEQLSSSLKQK---EQQLKEVAEKQEATRQDHAQQLATAAEEREASLRERDAALKQLEALEK------ 611
Cdd:COG3096    526 QRLRQQQNAERLLEEFCQRIGQQldaAEELEELLAELEAQLEELEEQAAEAVEQRSELRQQLEQLRARIKELAArapawl 605

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  612 EKAAKLEILQQQLqvaNEARDSAQtSVTQAQREKAELSRKVEelqacvetarQEQHEAQAQVAELELQLRSEQQKA-TEK 690
Cdd:COG3096    606 AAQDALERLREQS---GEALADSQ-EVTAAMQQLLEREREAT----------VERDELAARKQALESQIERLSQPGgAED 671

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  691 ERVAQEKDQL---------------------------------------QEQLQALK---ESLKVTKG----------SL 718
Cdd:COG3096    672 PRLLALAERLggvllseiyddvtledapyfsalygparhaivvpdlsavKEQLAGLEdcpEDLYLIEGdpdsfddsvfDA 751

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  719 EEEKRRAADALEEQQ------------------RCISELKAETRSLVEQHKRERKELEEERAGRKGLEARL-QQLGEAHQ 779
Cdd:COG3096    752 EELEDAVVVKLSDRQwrysrfpevplfgraareKRLEELRAERDELAEQYAKASFDVQKLQRLHQAFSQFVgGHLAVAFA 831

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  780 AETEVlrrELAEAMAAQHTAESECEQLVKEVAAWRERYEDSQQEEAQYGAMfQEQLMTLKEE-----CEKARQELQEAKE 854
Cdd:COG3096    832 PDPEA---ELAALRQRRSELERELAQHRAQEQQLRQQLDQLKEQLQLLNKL-LPQANLLADEtladrLEELREELDAAQE 907

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  855 KVAGIESHselqiSRQQNELAELHANLARALQQVQEKEVRAQKLADDLSTLQEKMAATSKEVARLETLVRKAGEQQETAS 934
Cdd:COG3096    908 AQAFIQQH-----GKALAQLEPLVAVLQSDPEQFEQLQADYLQAKEQQRRLKQQIFALSEVVQRRPHFSYEDAVGLLGEN 982

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1370459521  935 RELV-------KEPARAGDRQPEWLEEQQGR--QFCSTQAALQAMEREAEQMGNELER 983
Cdd:COG3096    983 SDLNeklrarlEQAEEARREAREQLRQAQAQysQYNQVLASLKSSRDAKQQTLQELEQ 1040
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 582-812 2.88e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 55.16  E-value: 2.88e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  582 AQQLATAAEEREASLRERDAALKQLEALEKEKAAKLEILQQQLQVANEARDSAQTSVTQAQREKAELSRKVEELQACVET 661
Cdd:COG4942     15 AAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAE 94

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  662 ARQEQHEAQAQVAEL-----------ELQLRSEQQKATEKERVAQEKDQLQEQLQALKESLKVTKGSLEEEKRRAADALE 730
Cdd:COG4942     95 LRAELEAQKEELAELlralyrlgrqpPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERA 174

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  731 EQQRCISELKAETRSLveqhkrerkelEEERAGRKGLEARLQQLGEAHQAETEVLRRELAEAMAAQHTAESECEQLVKEV 810
Cdd:COG4942    175 ELEALLAELEEERAAL-----------EALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERT 243


                   ..
gi 1370459521  811 AA 812
Cdd:COG4942    244 PA 245
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 218-789 3.01e-07

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 56.00  E-value: 3.01e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  218 RLKKQLADERSNRDELELELAENRKLLTEkDAQIAMMQQRIDRLALLnekQAASPLEPKELEELRDKNESLTmRLHETLK 297
Cdd:pfam12128  307 NGELSAADAAVAKDRSELEALEDQHGAFL-DADIETAAADQEQLPSW---QSELENLEERLKALTGKHQDVT-AKYNRRR 381

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  298 QC--QDLKTEKSQMDRKINQLSEENGDLsfkLREFASHLQQLQdalNELTEEHSKATQEWLEKQAQLEKELSAA------ 369
Cdd:pfam12128  382 SKikEQNNRDIAGIKDKLAKIREARDRQ---LAVAEDDLQALE---SELREQLEAGKLEFNEEEYRLKSRLGELklrlnq 455

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  370 -------LQDKKCLEEKNEILQGKLSQLEEHLSQLQDNPPQEKGEVLGdvlQLETLKQEAATLAANNTQLQARVEMLETE 442
Cdd:pfam12128  456 atatpelLLQLENFDERIERAREEQEAANAEVERLQSELRQARKRRDQ---ASEALRQASRRLEERQSALDELELQLFPQ 532

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  443 RGQQEAKLLAERGHFEEEKQQLSS----LITDLQSSISNLSQAKE--------ELEQ----ASQAHGARLTAQVASLTSE 506
Cdd:pfam12128  533 AGTLLHFLRKEAPDWEQSIGKVISpellHRTDLDPEVWDGSVGGElnlygvklDLKRidvpEWAASEEELRERLDKAEEA 612

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  507 LTTLNATIQQQDQELAGLKQQAKEKQAQLAQTLQQQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEATRQDHAQQL- 585
Cdd:pfam12128  613 LQSAREKQAAAEEQLVQANGELEKASREETFARTALKNARLDLRRLFDEKQSEKDKKNKALAERKDSANERLNSLEAQLk 692

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  586 -------ATAAEEREASLRERDAALKQLEALEKEKAAKLEILQQQLQVANEARDsAQTSVTQAQREK------------A 646
Cdd:pfam12128  693 qldkkhqAWLEEQKEQKREARTEKQAYWQVVEGALDAQLALLKAAIAARRSGAK-AELKALETWYKRdlaslgvdpdviA 771

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  647 ELSRKVEELQACVETARQEQHEAQAQVAELELQLRSEQQK-ATEKERVAQEKDQLQEQLQALKESLKVTKGSLEEEKRRA 725
Cdd:pfam12128  772 KLKREIRTLERKIERIAVRRQEVLRYFDWYQETWLQRRPRlATQLSNIERAISELQQQLARLIADTKLRRAKLEMERKAS 851

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1370459521  726 ADALEEQQRCISELKAETRSLVEQHKRERKELEEERAGRKglEARLQQLGEAHQAETEVLRREL 789
Cdd:pfam12128  852 EKQQVRLSENLRGLRCEMSKLATLKEDANSEQAQGSIGER--LAQLEDLKLKRDYLSESVKKYV 913
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 443-1267 3.18e-07

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 56.11  E-value: 3.18e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  443 RGQQEAKLLAERGHFEEEKQQLSS--LITDLQSSISNLSQAKEELEQASQA---------HGARLTAQVASLTSELTTLN 511
Cdd:COG3096    281 RELSERALELRRELFGARRQLAEEqyRLVEMARELEELSARESDLEQDYQAasdhlnlvqTALRQQEKIERYQEDLEELT 360

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  512 ATIQQQDQELAGlkqqAKEKQAQLAQTLQQQEQASQGLRHQVEQLSSSLKqkEQQLKEVAEKQEATRQDHAQQLATAAEE 591
Cdd:COG3096    361 ERLEEQEEVVEE----AAEQLAEAEARLEAAEEEVDSLKSQLADYQQALD--VQQTRAIQYQQAVQALEKARALCGLPDL 434

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  592 REASLRERDAALKqleALEKEKAAKLEILQQQLQVANEARD------------SAQTSVTQAQREKAELSRKVEELQACV 659
Cdd:COG3096    435 TPENAEDYLAAFR---AKEQQATEEVLELEQKLSVADAARRqfekayelvckiAGEVERSQAWQTARELLRRYRSQQALA 511

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  660 ETARQeqheAQAQVAELElQLRSEQQKAtekERVAQEKDQLQEQLQALKESLKVTKGSLEEEKrraaDALEEQQRCISEL 739
Cdd:COG3096    512 QRLQQ----LRAQLAELE-QRLRQQQNA---ERLLEEFCQRIGQQLDAAEELEELLAELEAQL----EELEEQAAEAVEQ 579

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  740 KAETRSLVEQHKRERKELEEERAGRKGLEARLQQLGEaHQAETEVLRRELAEAMAAQHTAESECEQLVKEVAAWRERYED 819
Cdd:COG3096    580 RSELRQQLEQLRARIKELAARAPAWLAAQDALERLRE-QSGEALADSQEVTAAMQQLLEREREATVERDELAARKQALES 658

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  820 SQQEEAQYGAMFQEQLMTLKEE------CE------------------KARQ-----ELQEAKEKVAGIESHSE--LQIS 868
Cdd:COG3096    659 QIERLSQPGGAEDPRLLALAERlggvllSEiyddvtledapyfsalygPARHaivvpDLSAVKEQLAGLEDCPEdlYLIE 738

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  869 RQQNELAElhanlarALQQVQEKEVRaqkladDLSTLQEKMAATSK--EVARLEtlvRKAGEQQ-ETASRE---LVKEPA 942
Cdd:COG3096    739 GDPDSFDD-------SVFDAEELEDA------VVVKLSDRQWRYSRfpEVPLFG---RAAREKRlEELRAErdeLAEQYA 802

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  943 -RAGDRQPEWLEEQQGRQFCSTQAALqAMEREAEQmgnELERLRAALMESQGQQQEERGQQEREVARLTQERGRAQADLA 1021
Cdd:COG3096    803 kASFDVQKLQRLHQAFSQFVGGHLAV-AFAPDPEA---ELAALRQRRSELERELAQHRAQEQQLRQQLDQLKEQLQLLNK 878

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1022 LEKAARAELEMRLQNALNEQRVEFATLQEALAH------ALTEKEGKdqeLAKLRgleaAQIKELEELRQTVKQLKEQLa 1095
Cdd:COG3096    879 LLPQANLLADETLADRLEELREELDAAQEAQAFiqqhgkALAQLEPL---VAVLQ----SDPEQFEQLQADYLQAKEQQ- 950

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1096 kkeKEHASGSGAQSEAAGRTEPTG-PKLEALRAEVSKLEqqcqkqqeqaDSLERSLEAERASRAERDSALETLQGQLEEK 1174
Cdd:COG3096    951 ---RRLKQQIFALSEVVQRRPHFSyEDAVGLLGENSDLN----------EKLRARLEQAEEARREAREQLRQAQAQYSQY 1017

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1175 AQELGHSQSALASAQRELAAFRTKVQDHSKAEDEwkAQVARGRQEAERKNSLISSLEEEVSILNRQVLEKEGESKELKRL 1254
Cdd:COG3096   1018 NQVLASLKSSRDAKQQTLQELEQELEELGVQADA--EAEERARIRRDELHEELSQNRSRRSQLEKQLTRCEAEMDSLQKR 1095

                          890
                   ....*....|...
gi 1370459521 1255 VMAESEKSQKLEE 1267
Cdd:COG3096   1096 LRKAERDYKQERE 1108
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 578-1429 3.26e-07

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 56.11  E-value: 3.26e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  578 RQDHAQQLATAAEEREASLRERDAALKQLEALEKE---KAAKLEILQQQLQVANEARDSAQTSVtqAQREKAElsRKVEE 654
Cdd:COG3096    280 RRELSERALELRRELFGARRQLAEEQYRLVEMAREleeLSARESDLEQDYQAASDHLNLVQTAL--RQQEKIE--RYQED 355

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  655 LQACVETARqEQHEAQAQVAElELQLRSEQQKATEKErVAQEKDQLQEQLQALkeslkvtkgslEEEKRRA------ADA 728
Cdd:COG3096    356 LEELTERLE-EQEEVVEEAAE-QLAEAEARLEAAEEE-VDSLKSQLADYQQAL-----------DVQQTRAiqyqqaVQA 421

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  729 LEEQQRCISELKAETRSLVEQHKRERKELEEERAGRKGLEARLQqlgeahqaetevlrreLAEAMAAQHtaeSECEQLVK 808
Cdd:COG3096    422 LEKARALCGLPDLTPENAEDYLAAFRAKEQQATEEVLELEQKLS----------------VADAARRQF---EKAYELVC 482

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  809 EVAAWRERYEDSQQeeaqygamfqeqlmtlkeecekARQELQEAKEKVAGIESHSelQISRQQNELAELHANLARALQQV 888
Cdd:COG3096    483 KIAGEVERSQAWQT----------------------ARELLRRYRSQQALAQRLQ--QLRAQLAELEQRLRQQQNAERLL 538

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  889 QEKEVRAQKLADDLSTLQEKMAATSKEVARLETLVRKAGEQQETASRELVKEPARA---GDRQPEW---------LEEQQ 956
Cdd:COG3096    539 EEFCQRIGQQLDAAEELEELLAELEAQLEELEEQAAEAVEQRSELRQQLEQLRARIkelAARAPAWlaaqdalerLREQS 618

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  957 GRQFCSTQAALQAM------EREAEQMGNELERLRAALMESQGQQQEERGQQEREVARLTQERG-----RAQADLALEKA 1025
Cdd:COG3096    619 GEALADSQEVTAAMqqllerEREATVERDELAARKQALESQIERLSQPGGAEDPRLLALAERLGgvllsEIYDDVTLEDA 698

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1026 AraELEMRLQNA--------LNEQRVEFATLQEAL--------------AHALTEKEGKDQELAKLRGLE---------- 1073
Cdd:COG3096    699 P--YFSALYGPArhaivvpdLSAVKEQLAGLEDCPedlyliegdpdsfdDSVFDAEELEDAVVVKLSDRQwrysrfpevp 776

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1074 ----AAQIKELEELRQTVKQLKEQLA-------KKEKEHASGS---GAQSEAAGRTEPTgPKLEALRAEVSKLeqqcqkq 1139
Cdd:COG3096    777 lfgrAAREKRLEELRAERDELAEQYAkasfdvqKLQRLHQAFSqfvGGHLAVAFAPDPE-AELAALRQRRSEL------- 848

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1140 qeqadslERSLEAERASRAERDSALETLQGQLEEKAQELGHsqsALASAQRELAAFRTKVQDHSKAEDEWKAQVARGRQE 1219
Cdd:COG3096    849 -------ERELAQHRAQEQQLRQQLDQLKEQLQLLNKLLPQ---ANLLADETLADRLEELREELDAAQEAQAFIQQHGKA 918

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1220 AERknslissLEEEVSILNRQVLEKEGESKELKRLVMAESEKSQKLEERLRLLQAETA---SNSARAAERSSALREEVQS 1296
Cdd:COG3096    919 LAQ-------LEPLVAVLQSDPEQFEQLQADYLQAKEQQRRLKQQIFALSEVVQRRPHfsyEDAVGLLGENSDLNEKLRA 991

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1297 LREEAEKQRvasenlrqeltsqaeraEELGQELKAWQEKFFQKEQALSTLQLEHTSTQALVSELLPA-KHLCQQLQAEQA 1375
Cdd:COG3096    992 RLEQAEEAR-----------------REAREQLRQAQAQYSQYNQVLASLKSSRDAKQQTLQELEQElEELGVQADAEAE 1054

                          890       900       910       920       930
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1370459521 1376 AAEKRHREELEQSKQAAGGLRAELLRA-QRELGELIPLRQKVAEQERTAQQLRAE 1429
Cdd:COG3096   1055 ERARIRRDELHEELSQNRSRRSQLEKQlTRCEAEMDSLQKRLRKAERDYKQEREQ 1109
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 1074-1701 3.29e-07

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 55.75  E-value: 3.29e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1074 AAQIKELEELRQTVKQLKEQLAKKEKEHASGSGAQS--EAAGRTEPTGPKLEALRAEVSKLEQQCQKQQEQADSLERSlE 1151
Cdd:TIGR00618  222 QVLEKELKHLREALQQTQQSHAYLTQKREAQEEQLKkqQLLKQLRARIEELRAQEAVLEETQERINRARKAAPLAAHI-K 300

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1152 AERASRAERDSALETLQGQLEEKAQELGHSQSALASaqrelaafRTKVQDHSKAEDEWKAQVARGRQEAERKNSLISSLE 1231
Cdd:TIGR00618  301 AVTQIEQQAQRIHTELQSKMRSRAKLLMKRAAHVKQ--------QSSIEEQRRLLQTLHSQEIHIRDAHEVATSIREISC 372

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1232 EEVSILNRqvlekegeSKELKRLVMAESEKSQKLEERLRLLQAETASNSARAAERS------SALREEVQSLREEAEKQR 1305
Cdd:TIGR00618  373 QQHTLTQH--------IHTLQQQKTTLTQKLQSLCKELDILQREQATIDTRTSAFRdlqgqlAHAKKQQELQQRYAELCA 444

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1306 VASENLRQELTSQAERAEELGQELKAWQEKFFQKEQALSTLQLEHTSTQALV------------SELLPAKHLCQQLQ-- 1371
Cdd:TIGR00618  445 AAITCTAQCEKLEKIHLQESAQSLKEREQQLQTKEQIHLQETRKKAVVLARLlelqeepcplcgSCIHPNPARQDIDNpg 524

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1372 ------AEQAAAEKRHREELEQSKQAAGGLRAELLR----AQRELGELIPLRQKVAEQERTAQQLRAEKASYAEQLSMLK 1441
Cdd:TIGR00618  525 pltrrmQRGEQTYAQLETSEEDVYHQLTSERKQRASlkeqMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLS 604

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1442 KAHGLLAEENRGLGERAN--LGRQFLEVELDQAREKYVQELAAVRADAETRLAEVQREAQSTARELEvmtAKYEGAKVKV 1519
Cdd:TIGR00618  605 EAEDMLACEQHALLRKLQpeQDLQDVRLHLQQCSQELALKLTALHALQLTLTQERVREHALSIRVLP---KELLASRQLA 681

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1520 LEERQRFQEERQKLTAQVEQLEVFQREQTKQVEELSKKLADSDQASKVQQQKLKAVQAQGGESQQEAQRLQ----AQLNE 1595
Cdd:TIGR00618  682 LQKMQSEKEQLTYWKEMLAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQArtvlKARTE 761

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1596 LQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQELQEQLRSLE-QLQKENKELRAEAERLGHELQQAGLKTKEAEQTCR 1674
Cdd:TIGR00618  762 AHFNNNEEVTAALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEaEIGQEIPSDEDILNLQCETLVQEEEQFLSRLEEKS 841

                          650       660
                   ....*....|....*....|....*..
gi 1370459521 1675 HLTAQVRSLEAQVAHADQQLRDLGKFQ 1701
Cdd:TIGR00618  842 ATLGEITHQLLKYEECSKQLAQLTQEQ 868
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 687-917 4.12e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 54.77  E-value: 4.12e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  687 ATEKERVAQEKDQLQEQLQALKESLKvtkgSLEEEKRRAADALEEQQRCISELKAETRSLVEQHKRERKELEEERAGRKG 766
Cdd:COG4942     19 ADAAAEAEAELEQLQQEIAELEKELA----ALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAE 94

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  767 LEARLQQLGEAHQAETEVLRRELAEAMAAQHTAESECEQLVKeVAAWRERYEDSQQEEAQYGAMFQEQLMTLKEECEKAR 846
Cdd:COG4942     95 LRAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVR-RLQYLKYLAPARREQAEELRADLAELAALRAELEAER 173

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1370459521  847 QELQEAKEKVAGIESHSELQISRQQNELAELHANLARALQQVQEKEVRAQKLADDLSTLQEKMAATSKEVA 917
Cdd:COG4942    174 AELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTP 244
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 209-625 6.67e-07

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 54.64  E-value: 6.67e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  209 LQTPQFQMRRLKKQLADERSNrdELELELAENRKLLTEKDAQIAMMQQRIDRLallneKQAASPLEpKELEELRDKNESL 288
Cdd:TIGR04523  290 LNQLKSEISDLNNQKEQDWNK--ELKSELKNQEKKLEEIQNQISQNNKIISQL-----NEQISQLK-KELTNSESENSEK 361

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  289 TMRLHETLKQCQDLKTEKSQMDRKINQLSEENGDLSFKLREFASHLQQLQDALNELTEEH---SKATQEWLEKQAQLEKE 365
Cdd:TIGR04523  362 QRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKellEKEIERLKETIIKNNSE 441

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  366 LSAALQDKKCLEEKNEILQGKLSQLEEHLSQLQDNPPQEKGEVLGDVLQLETLKQEAATLAANNTQLQARVEMLETERGQ 445
Cdd:TIGR04523  442 IKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISS 521

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  446 qeakllaerghFEEEKQQLSSLITDLQSSISNLSQAKEELEQasqahgarltaqvaSLTSELttLNATIQQQDQELAGLK 525
Cdd:TIGR04523  522 -----------LKEKIEKLESEKKEKESKISDLEDELNKDDF--------------ELKKEN--LEKEIDEKNKEIEELK 574

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  526 QQAKekqaqlaqtlqqqeqasqglrhqveqlssSLKQKEQQLKEVAEKQEATRQDHAQQLA---TAAEEREASLRERDAA 602
Cdd:TIGR04523  575 QTQK-----------------------------SLKKKQEEKQELIDQKEKEKKDLIKEIEekeKKISSLEKELEKAKKE 625

                          410       420
                   ....*....|....*....|...
gi 1370459521  603 LKQLEALEKEKAAKLEILQQQLQ 625
Cdd:TIGR04523  626 NEKLSSIIKNIKSKKNKLKQEVK 648
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 347-1096 6.85e-07

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 54.97  E-value: 6.85e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  347 EHSKATQEWLEKQAQLEKELSAALQDKKCLEEKNEILQGKLSQLEEHLSQLQDNPPQEKgevlgdvlqlETLKQEAATLA 426
Cdd:TIGR00618  163 KEKKELLMNLFPLDQYTQLALMEFAKKKSLHGKAELLTLRSQLLTLCTPCMPDTYHERK----------QVLEKELKHLR 232

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  427 ANNTQLQARVEMLetergQQEAKLLAERGHFEEEKQQLSSLITDLQSSISNLSQAKEELEQASQ-AHGARLTAQVASLTS 505
Cdd:TIGR00618  233 EALQQTQQSHAYL-----TQKREAQEEQLKKQQLLKQLRARIEELRAQEAVLEETQERINRARKaAPLAAHIKAVTQIEQ 307

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  506 ELTTLNATIQQQDQELAGLKQQAKEKQAQLAQTLQQQEQASQglRHQVEQLSSSLKQKEQQLKEVAEKQEATRQDHAQQl 585
Cdd:TIGR00618  308 QAQRIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQT--LHSQEIHIRDAHEVATSIREISCQQHTLTQHIHTL- 384

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  586 ataaEEREASLRERDAALKQLEALEKEKAAKLEILQQQLQVANEARDSAQTSVTQAQREKAELSRKVEELQACVETARQE 665
Cdd:TIGR00618  385 ----QQQKTTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIH 460

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  666 QHEAQAQVAELELQLRSEQQKATEKERVAQEKDQLQEQLQALKESLKVTKGSLEEEkRRAADALEEQQRCISELKAETRS 745
Cdd:TIGR00618  461 LQESAQSLKEREQQLQTKEQIHLQETRKKAVVLARLLELQEEPCPLCGSCIHPNPA-RQDIDNPGPLTRRMQRGEQTYAQ 539

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  746 LVEQHKRERKELEEERAGRKGLEARLQQLGEAHQAETEVLRRELAEAMAAQHTAESECEQLVKEVAAWRERYEDSQQEEA 825
Cdd:TIGR00618  540 LETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLACEQHALLR 619

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  826 QygamFQEQLMTLKEECEKARQELQEAKEKVAGIESHSELQISRQQNELAELHANLARALQQVQEKEVRAQKLADDLSTL 905
Cdd:TIGR00618  620 K----LQPEQDLQDVRLHLQQCSQELALKLTALHALQLTLTQERVREHALSIRVLPKELLASRQLALQKMQSEKEQLTYW 695

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  906 QEKMAATSKEVARLETLV---RKAGEQQETASRELVKEPARAGDRQPEWLEEQQGRQFCSTQAALQAMEREAEQMGNELE 982
Cdd:TIGR00618  696 KEMLAQCQTLLRELETHIeeyDREFNEIENASSSLGSDLAAREDALNQSLKELMHQARTVLKARTEAHFNNNEEVTAALQ 775

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  983 RLraalmesqgqqqeerGQQEREVARLTQERGRAQADLALEKAARAELEMRLQNALNEQRVEFATLQEALAHALTEKEGK 1062
Cdd:TIGR00618  776 TG---------------AELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQCETLVQEEEQFLSRLEEK 840

                          730       740       750
                   ....*....|....*....|....*....|....
gi 1370459521 1063 DQELAKLRgleaAQIKELEELRQTVKQLKEQLAK 1096
Cdd:TIGR00618  841 SATLGEIT----HQLLKYEECSKQLAQLTQEQAK 870
mukB PRK04863
chromosome partition protein MukB;
598-1427 6.96e-07

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 54.96  E-value: 6.96e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  598 ERDAALKQLEALEKEKAAKLEILQQQLQVANEARDSAQTSVTQAQREKAELSRKVEELQACVETARQEQHEAQAQVAELE 677
Cdd:PRK04863   280 ERRVHLEEALELRRELYTSRRQLAAEQYRLVEMARELAELNEAESDLEQDYQAASDHLNLVQTALRQQEKIERYQADLEE 359

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  678 LQLRSEQQKATEKErVAQEKDQLQEQLQALKESLKVTKGSLEEEKRraadALEEQQrciselkaeTRSLVEQHKRERKEL 757
Cdd:PRK04863   360 LEERLEEQNEVVEE-ADEQQEENEARAEAAEEEVDELKSQLADYQQ----ALDVQQ---------TRAIQYQQAVQALER 425

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  758 EEERAGR-----KGLEARLQQLGEAHQAETEVL-----RRELAEAMAAQHTaesECEQLVKEVAAWRERyedsqqEEAQY 827
Cdd:PRK04863   426 AKQLCGLpdltaDNAEDWLEEFQAKEQEATEELlsleqKLSVAQAAHSQFE---QAYQLVRKIAGEVSR------SEAWD 496

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  828 GAmfqeqlmtlKEECEKARQELQEAkEKVAGIES-HSEL-QISRQQNELAELHANLARALQQVQEKEVRAQKLADDLSTL 905
Cdd:PRK04863   497 VA---------RELLRRLREQRHLA-EQLQQLRMrLSELeQRLRQQQRAERLLAEFCKRLGKNLDDEDELEQLQEELEAR 566

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  906 QEKMAATSKEVARLETLVRKAGEQQETASRELVKeparagdRQPEW---------LEEQQGRQFCSTQAALQAM------ 970
Cdd:PRK04863   567 LESLSESVSEARERRMALRQQLEQLQARIQRLAA-------RAPAWlaaqdalarLREQSGEEFEDSQDVTEYMqqller 639

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  971 EREAEQMGNELERLRAALMESQGQQQEERGQQEREVARLTQERG-----RAQADLALEKAAraELEMRLQNA-------- 1037
Cdd:PRK04863   640 ERELTVERDELAARKQALDEEIERLSQPGGSEDPRLNALAERFGgvllsEIYDDVSLEDAP--YFSALYGPArhaivvpd 717

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1038 LNEQRVEFATLQ-----------------------EALAHALTEKEGKDQ-ELAKLRGL----EAAQIKELEELRQTVKQ 1089
Cdd:PRK04863   718 LSDAAEQLAGLEdcpedlyliegdpdsfddsvfsvEELEKAVVVKIADRQwRYSRFPEVplfgRAAREKRIEQLRAEREE 797

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1090 LKEQLAKKEKEHAsgsgaqseaagrteptgpKLEALRAEVSKLEQQCQKQQEQADSlERSLEAERASRAERDSALETLQG 1169
Cdd:PRK04863   798 LAERYATLSFDVQ------------------KLQRLHQAFSRFIGSHLAVAFEADP-EAELRQLNRRRVELERALADHES 858

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1170 QLEEKAQELGHSQSALASAQRELAAFRT-KVQDHSKAEDEWKAQVARGrQEAER----KNSLISSLEEEVSILNrqvlEK 1244
Cdd:PRK04863   859 QEQQQRSQLEQAKEGLSALNRLLPRLNLlADETLADRVEEIREQLDEA-EEAKRfvqqHGNALAQLEPIVSVLQ----SD 933

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1245 EGESKELKRLVMAESEKSQKLEERLRLLqaetASNSARAAERSSAlrEEVQSLREEAEkqrvASENLRQELTSQAERAEE 1324
Cdd:PRK04863   934 PEQFEQLKQDYQQAQQTQRDAKQQAFAL----TEVVQRRAHFSYE--DAAEMLAKNSD----LNEKLRQRLEQAEQERTR 1003

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1325 LGQELKAWQEKFFQKEQALSTLQLEHTSTQALVSELLPA-KHLCQQLQAEQAAAEKRHREELEQSKQAAGGLRAELLRAQ 1403
Cdd:PRK04863  1004 AREQLRQAQAQLAQYNQVLASLKSSYDAKRQMLQELKQElQDLGVPADSGAEERARARRDELHARLSANRSRRNQLEKQL 1083

                          890       900
                   ....*....|....*....|....*
gi 1370459521 1404 -RELGELIPLRQKVAEQERTAQQLR 1427
Cdd:PRK04863  1084 tFCEAEMDNLTKKLRKLERDYHEMR 1108
MARTX_Nterm NF012221
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...
 253-656 7.47e-07

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.


Pssm-ID: 467957 [Multi-domain]  Cd Length: 1848  Bit Score: 54.84  E-value: 7.47e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  253 MMQQRIDRLALLNEKQAASPLEPKeLEELRDKNESLTMRLHETLKQCQDLK-TEKSQMDRKINQLSEENGDLSFKLREFA 331
Cdd:NF012221  1457 LTAGEVIALSFDFARRAGLSTNNG-IEVLWNGEVVFASSGDASAWQQKTLKlTAKAGSNRLEFKGTGHNDGLGYILDNVV 1535

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  332 --SHLQQLQDALNELTEEhSKATQEwlekqaqlekelsaALQDKKCLEEKNEILQGKLSQLEEHLSQLQ---DNPPQEKG 406
Cdd:NF012221  1536 atSESSQQADAVSKHAKQ-DDAAQN--------------ALADKERAEADRQRLEQEKQQQLAAISGSQsqlESTDQNAL 1600

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  407 EVLGDVlQLETLKQEAATLAANNTQLQARVEMLET------ERGQQeakllaERGHFEEekqqlsSLITDLQSSISNLSQ 480
Cdd:NF012221  1601 ETNGQA-QRDAILEESRAVTKELTTLAQGLDALDSqatyagESGDQ------WRNPFAG------GLLDRVQEQLDDAKK 1667

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  481 -AKEELEQASQAHGARLT-AQVASLTSELTTLNATIQQQDQELAGlkQQAKEKQAQLAQTLQQQEQASQglrhQVEQLSS 558
Cdd:NF012221  1668 iSGKQLADAKQRHVDNQQkVKDAVAKSEAGVAQGEQNQANAEQDI--DDAKADAEKRKDDALAKQNEAQ----QAESDAN 1741

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  559 SLKQKEQQLKEVAEKQEATRQDHAQQLATAAEEREASLRERDAALKQL---EALEKEKAAK-LEILQQQLQVANEARDSA 634
Cdd:NF012221  1742 AAANDAQSRGEQDASAAENKANQAQADAKGAKQDESDKPNRQGAAGSGlsgKAYSVEGVAEpGSHINPDSPAAADGRFSE 1821

                          410       420
                   ....*....|....*....|..
gi 1370459521  635 QTSvTQAQREKAELSRKVEELQ 656
Cdd:NF012221  1822 GLT-EQEQEALEGATNAVNRLQ 1842
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 263-881 1.07e-06

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 54.28  E-value: 1.07e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  263 LLNEKQAASPLEPKELEELRDKNESLTMRLHetlKQCQDLKTEKSQMDRKINQLSEENGDLSFKLREfashLQQLQDALN 342
Cdd:TIGR00606  413 LCADLQSKERLKQEQADEIRDEKKGLGRTIE---LKKEILEKKQEELKFVIKELQQLEGSSDRILEL----DQELRKAER 485

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  343 ELTEEHSKATQEWLEKQAQLEKELSAALQDKKC-LEEKNEILQGKLSQLEEHLS----------QLQDNPPQEKGEV--- 408
Cdd:TIGR00606  486 ELSKAEKNSLTETLKKEVKSLQNEKADLDRKLRkLDQEMEQLNHHTTTRTQMEMltkdkmdkdeQIRKIKSRHSDELtsl 565

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  409 LGDVLQLETLKQEAATLAANNTQLQARVEMLETERGQQEAKLLAERGHFEEEKQQLSSLITDL------QSSISNLSQAK 482
Cdd:TIGR00606  566 LGYFPNKKQLEDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKLfdvcgsQDEESDLERLK 645

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  483 EELEQASQ--AHGARLTAQVASLTSELTTLN--------------ATIQQQDQELAGLKQQAKEKQAQLAQTLQQQEQAS 546
Cdd:TIGR00606  646 EEIEKSSKqrAMLAGATAVYSQFITQLTDENqsccpvcqrvfqteAELQEFISDLQSKLRLAPDKLKSTESELKKKEKRR 725

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  547 QGLRHQVEQLSSSLKQKEQQLKEVAEKQEATRQDhAQQLATAAEEREASLRERDAALKQLEALEKEkAAKLEILQQQL-- 624
Cdd:TIGR00606  726 DEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRD-IQRLKNDIEEQETLLGTIMPEEESAKVCLTD-VTIMERFQMELkd 803

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  625 -------QVANEARDSAQTSVTQAQREKAE-------LSRKVEELQACVETARQEQHEAQAQVAELELQLRSEQQKATEK 690
Cdd:TIGR00606  804 verkiaqQAAKLQGSDLDRTVQQVNQEKQEkqheldtVVSKIELNRKLIQDQQEQIQHLKSKTNELKSEKLQIGTNLQRR 883

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  691 ERVAQEKDQLQEQLQALKESLKVTKGSLEEEKRRAADALEEQQRCISELKAETRSLVEQHKRERKELEEERAGRKGLEAR 770
Cdd:TIGR00606  884 QQFEEQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEELISSKETSNKKAQDKVNDIKEKVKNIHGYMKDIENK 963

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  771 LQQLGEAHQAETEvlrRELAEAMAAQHTAESECEQLVKEVAAWRERYEDSQQEEaqygAMFQEQLMTLKEEcekarQELQ 850
Cdd:TIGR00606  964 IQDGKDDYLKQKE---TELNTVNAQLEECEKHQEKINEDMRLMRQDIDTQKIQE----RWLQDNLTLRKRE-----NELK 1031

                          650       660       670
                   ....*....|....*....|....*....|..
gi 1370459521  851 EAKEKVAGIESH-SELQISRQQNELAELHANL 881
Cdd:TIGR00606 1032 EVEEELKQHLKEmGQMQVLQMKQEHQKLEENI 1063
PRK11281 PRK11281
mechanosensitive channel MscK;
445-718 1.78e-06

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 53.38  E-value: 1.78e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  445 QQEAKLLAERGHFEEEKQQLSSLITDLQSSISNLSQAKEELEQASQaHGARLTAQVASLTSELTTLNATIQQQD-QELAG 523
Cdd:PRK11281    42 QAQLDALNKQKLLEAEDKLVQQDLEQTLALLDKIDRQKEETEQLKQ-QLAQAPAKLRQAQAELEALKDDNDEETrETLST 120

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  524 L------KQQAKEKQAQLAQTLQQQEQASQ--GLRHQVE----QLSSSLKQKEQ---QLKEVAEKQEATRQDHAQQLATA 588
Cdd:PRK11281   121 LslrqleSRLAQTLDQLQNAQNDLAEYNSQlvSLQTQPEraqaALYANSQRLQQirnLLKGGKVGGKALRPSQRVLLQAE 200

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  589 AEEREASLRERDAALK---QLEALEK----EKAAKLEILQQQLQVAneardsaQTSVTQAQREKAElsRKVEELQACVET 661
Cdd:PRK11281   201 QALLNAQNDLQRKSLEgntQLQDLLQkqrdYLTARIQRLEHQLQLL-------QEAINSKRLTLSE--KTVQEAQSQDEA 271

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1370459521  662 ARQEQHEAQAQVAELELQLRSEQQKATEKE--------RVAQEKDQLQEQLQALKESLKVTKGSL 718
Cdd:PRK11281   272 ARIQANPLVAQELEINLQLSQRLLKATEKLntltqqnlRVKNWLDRLTQSERNIKEQISVLKGSL 336
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 458-687 1.87e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 52.46  E-value: 1.87e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  458 EEEKQQLSSLITDLQSSISNLSQAKEELEQASQAhgarLTAQVASLTSELTTLNATIQQQDQELAGLKQQAKEKQAQLAQ 537
Cdd:COG4942     26 EAELEQLQQEIAELEKELAALKKEEKALLKQLAA----LERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEA 101

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  538 TLQQQEqasqglrhqvEQLSSSLKQKEQQLKEVAEKQEATRQ--DHAQQLATAAEEREASLRERDAALKQLEALEKEKAA 615
Cdd:COG4942    102 QKEELA----------ELLRALYRLGRQPPLALLLSPEDFLDavRRLQYLKYLAPARREQAEELRADLAELAALRAELEA 171

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1370459521  616 KLEILQQQLQVANEARDSAQTSVTQAQREKAELSRKVEELQACVETARQEQHEAQAQVAELELQLRSEQQKA 687
Cdd:COG4942    172 ERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERT 243
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 596-749 1.89e-06

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 51.08  E-value: 1.89e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  596 LRERDAALKQLEALEKEKAAKLEILQQQLQVANEARDSAQTSVTQAQREKAELSRKVEELQACVETARQEQ------HEA 669
Cdd:COG1579     12 LQELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLgnvrnnKEY 91

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  670 QAQVAELELQLRSEQQKATEKERVAQEKDQLQEQLQALKESLKVTKGSLEEEKRRAADALEEQQRCISELKAETRSLVEQ 749
Cdd:COG1579     92 EALQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAEREELAAK 171
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 211-670 2.09e-06

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 53.05  E-value: 2.09e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  211 TPQFQMRRLKKQLADERSNRDELELELAENRKLLTEKDAQI-AMMQQRIDRLALLNEKQAASPLEPKELEELRDKNESLT 289
Cdd:TIGR00618  448 TCTAQCEKLEKIHLQESAQSLKEREQQLQTKEQIHLQETRKkAVVLARLLELQEEPCPLCGSCIHPNPARQDIDNPGPLT 527

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  290 MRLHETLKQCQDLKTEKSQMDRKINQLSEENGDLSFKLREFASHLQQLQDALNELTEEHSKATQEWLEKQAQLEKELSAA 369
Cdd:TIGR00618  528 RRMQRGEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAE 607

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  370 LQDKKCLEEKNEILQGKLSQLEEHLSQLQDNPPQEKGEVLGDVLQLETLKQEAATLAANNTQLQARVEMLETERGQQEAK 449
Cdd:TIGR00618  608 DMLACEQHALLRKLQPEQDLQDVRLHLQQCSQELALKLTALHALQLTLTQERVREHALSIRVLPKELLASRQLALQKMQS 687

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  450 LLAERGHFEEEKQQLSSLITDLQSSISNLSQAKEELEQASQAHGARLTAQVASLTSELTTLNATIQQQDQELAGLKQQAK 529
Cdd:TIGR00618  688 EKEQLTYWKEMLAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQARTVLKARTEAHFNNN 767

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  530 EKQAQLAQTLQQQEQASQGLRHQVEQLSS---SLKQKEQQLKEVAEKQEATRQDHAQQLATAAEEREASLRERDAAL--- 603
Cdd:TIGR00618  768 EEVTAALQTGAELSHLAAEIQFFNRLREEdthLLKTLEAEIGQEIPSDEDILNLQCETLVQEEEQFLSRLEEKSATLgei 847

                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1370459521  604 -KQLEALEKEKAAKLEILQQQLQVANEARDSAQTSVTQAQREKAELSRKVEELQACVETARQEQHEAQ 670
Cdd:TIGR00618  848 tHQLLKYEECSKQLAQLTQEQAKIIQLSDKLNGINQIKIQFDGDALIKFLHEITLYANVRLANQSEGR 915
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 832-1042 2.24e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 52.07  E-value: 2.24e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  832 QEQLMTLKEECEKARQELQEAKEKVAGIEShselQISRQQNELAELHANLARALQQVQEKEVRAQKLADDLSTLQEKMAA 911
Cdd:COG4942     26 EAELEQLQQEIAELEKELAALKKEEKALLK----QLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEA 101

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  912 TSKEVARLETLVRKAGEQQETASRELVKEPARAGDRQpEWLE------EQQGRQFCSTQAALQAMEREAEQMGNELERLR 985
Cdd:COG4942    102 QKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRL-QYLKylaparREQAEELRADLAELAALRAELEAERAELEALL 180

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1370459521  986 AALMESQGQQQEERGQQEREVARLTQERGRAQADLALEKAARAELEMRLQNALNEQR 1042
Cdd:COG4942    181 AELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAA 237
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1211-1687 3.11e-06

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 52.73  E-value: 3.11e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1211 AQVARGRQEAERKNSLiSSLEEEVsilnrqvleKEGESKEL-KRLVMAESEKSQKLEERLRLLQ-----AETASNSARAA 1284
Cdd:PRK02224   174 ARLGVERVLSDQRGSL-DQLKAQI---------EEKEEKDLhERLNGLESELAELDEEIERYEEqreqaRETRDEADEVL 243

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1285 ERSSALREEVQSLREEAEKQRVA-------SENLRQELTSQAERAEELGQELkawqekffqkEQALSTLQLEHTSTQALv 1357
Cdd:PRK02224   244 EEHEERREELETLEAEIEDLRETiaetereREELAEEVRDLRERLEELEEER----------DDLLAEAGLDDADAEAV- 312

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1358 sellpakhlcQQLQAEQAAAEKRHREELEQSKQAAGGLRAEllrAQRELGELIPLRQKVAEQERTAQQLRAEKASYAEQL 1437
Cdd:PRK02224   313 ----------EARREELEDRDEELRDRLEECRVAAQAHNEE---AESLREDADDLEERAEELREEAAELESELEEAREAV 379

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1438 SMLKKAHGLLAEENRGLGERANlgrqFLEVELDQArEKYVQELAAVRADAETRLAEVQREAQSTARELEVMTAKYEGAK- 1516
Cdd:PRK02224   380 EDRREEIEELEEEIEELRERFG----DAPVDLGNA-EDFLEELREERDELREREAELEATLRTARERVEEAEALLEAGKc 454

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1517 ------------VKVLEERQrfqEERQKLTAQVEQLEVFQREQTKQVEELSKKLADSDQASKVQQQ-----KLKAVQAQG 1579
Cdd:PRK02224   455 pecgqpvegsphVETIEEDR---ERVEELEAELEDLEEEVEEVEERLERAEDLVEAEDRIERLEERredleELIAERRET 531

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1580 GESQQE-AQRLQAQLNELQAQLSQKEQAAEHYKLQMEKAKTH---YDAKKQQNQELQEQLRSLEQLQKENKELRAEAERL 1655
Cdd:PRK02224   532 IEEKRErAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEvaeLNSKLAELKERIESLERIRTLLAAIADAEDEIERL 611

                          490       500       510
                   ....*....|....*....|....*....|..
gi 1370459521 1656 GHELQQAGLKTKEAEQTCRHLTAQVRSLEAQV 1687
Cdd:PRK02224   612 REKREALAELNDERRERLAEKRERKRELEAEF 643
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 213-485 3.35e-06

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 52.75  E-value: 3.35e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  213 QFQMRRLKKQLADERSNRDELELELAENRKLLTEKDAQIAMMQQRIDRL-ALLNEKQAASPLEPKELEELRDKNESLTMR 291
Cdd:TIGR02168  753 SKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALrEALDELRAELTLLNEEAANLRERLESLERR 832

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  292 LHETLKQCQDLKTEKSQMDRKINQLSEENGDLSFKLREFAS---HLQQLQDALNELTEEHSKATQEWLEKQAQLEKELSA 368
Cdd:TIGR02168  833 IAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESeleALLNERASLEEALALLRSELEELSEELRELESKRSE 912

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  369 ALQDKKCLEEKNEILQGKLSQLEEHLSQLQDNPPqEKGEVLgdvlqLETLKQEAATLAANNTQLQARVEMLETERGQQEA 448
Cdd:TIGR02168  913 LRRELEELREKLAQLELRLEGLEVRIDNLQERLS-EEYSLT-----LEEAEALENKIEDDEEEARRRLKRLENKIKELGP 986

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|
gi 1370459521  449 KLLAERGHFEEEKQQ---LSSLITDLQSSISNLSQAKEEL 485
Cdd:TIGR02168  987 VNLAAIEEYEELKERydfLTAQKEDLTEAKETLEEAIEEI 1026
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
547-937 3.63e-06

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 52.08  E-value: 3.63e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  547 QGLRHQVEQLSSSLKQKEQQLKEVaeKQEATRQDHAQQLATAAEEREASLRERDAALKQLEALE------KEKAAKLEIL 620
Cdd:COG4717     91 AELQEELEELEEELEELEAELEEL--REELEKLEKLLQLLPLYQELEALEAELAELPERLEELEerleelRELEEELEEL 168

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  621 QQQLQVANEARDSAQTSVTQAQREK-AELSRKVEELQACVETARQEQHEAQAQVAELELQLRSEQQKAtekeRVAQEKDQ 699
Cdd:COG4717    169 EAELAELQEELEELLEQLSLATEEElQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENEL----EAAALEER 244

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  700 LQEQLQALK-----ESLKVTKGSLEEEKRRAADALEEQQRCISELKAETRSLVEQHKRERKELEEERAGRKGLEARLQQL 774
Cdd:COG4717    245 LKEARLLLLiaaalLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEEL 324

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  775 GEAHQAETEVLRRELAEAMAAQHTAesecEQLVKEVAAWRERYEDSQQEEAQYgAMFQEQLMTLKEECEKARQELQEAKE 854
Cdd:COG4717    325 LAALGLPPDLSPEELLELLDRIEEL----QELLREAEELEEELQLEELEQEIA-ALLAEAGVEDEEELRAALEQAEEYQE 399

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  855 KVAGIESHSElQISRQQNELAEL--HANLARALQQVQEKEVRAQKLADDLSTLQEKMAATSKEVARLET--LVRKAGEQQ 930
Cdd:COG4717    400 LKEELEELEE-QLEELLGELEELleALDEEELEEELEELEEELEELEEELEELREELAELEAELEQLEEdgELAELLQEL 478


                   ....*..
gi 1370459521  931 ETASREL 937
Cdd:COG4717    479 EELKAEL 485
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 467-706 4.31e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 51.30  E-value: 4.31e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  467 LITDLQSSISNLSQAKEELEQAsQAHGARLTAQVASLTSELTTLNATIQQQDQELAGLKQQAKEKQAQLAQTLQQQEQas 546
Cdd:COG4942     11 LALAAAAQADAAAEAEAELEQL-QQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAE-- 87

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  547 qgLRHQVEQLSSSLKQKEQQLKEVAEKQEATRQDHAQQLATAAEEREASLReRDAALKQLEALEKEKAAKLEILQQQLQV 626
Cdd:COG4942     88 --LEKEIAELRAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVR-RLQYLKYLAPARREQAEELRADLAELAA 164

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  627 ANEardsaqtsvtQAQREKAELSRKVEELQACVETARQEQHEAQAQVAELELQLRSEQQKATEKERVAQEKDQLQEQLQA 706
Cdd:COG4942    165 LRA----------ELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEA 234
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 218-713 4.41e-06

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 52.04  E-value: 4.41e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  218 RLKKQLADERSNRDELELELAENRKLLtEKDAQIAMMQQRIDRlallnekqaasplepkeleELRDKNESLtMRLHETLK 297
Cdd:pfam15921  378 QLQKLLADLHKREKELSLEKEQNKRLW-DRDTGNSITIDHLRR-------------------ELDDRNMEV-QRLEALLK 436

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  298 QcqdLKTE-KSQMDRKINQLSEENGDLSfKLREFASHLQQLQDALNELTEEHSkATQEWLEKQAQLEKELSAALQDK-KC 375
Cdd:pfam15921  437 A---MKSEcQGQMERQMAAIQGKNESLE-KVSSLTAQLESTKEMLRKVVEELT-AKKMTLESSERTVSDLTASLQEKeRA 511

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  376 LEEKNEILQG-------KLSQL------EEHLSQLQDNPPQEKGEVLGDVLQLETLKQEAATLAANNTQLQARVEMLETE 442
Cdd:pfam15921  512 IEATNAEITKlrsrvdlKLQELqhlkneGDHLRNVQTECEALKLQMAEKDKVIEILRQQIENMTQLVGQHGRTAGAMQVE 591

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  443 RGQQEAKLLAERGHFEE---EKQQLSSLITDLQSSISNLSQAKEELEQAsqahGARLTAQVASLTSELTTLNATIQQQDQ 519
Cdd:pfam15921  592 KAQLEKEINDRRLELQEfkiLKDKKDAKIRELEARVSDLELEKVKLVNA----GSERLRAVKDIKQERDQLLNEVKTSRN 667

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  520 ELAGLKQQAKEKQAQLAQTLQQQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKqeatrQDHAQQLATAAEEREASLRer 599
Cdd:pfam15921  668 ELNSLSEDYEVLKRNFRNKSEEMETTTNKLKMQLKSAQSELEQTRNTLKSMEGS-----DGHAMKVAMGMQKQITAKR-- 740

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  600 daalKQLEALEkekaAKLEILQQQLQVANEARDSAQTSVTQAQREKAELSRKVEELQACVETARQEQHEAQAQVAELELQ 679
Cdd:pfam15921  741 ----GQIDALQ----SKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANMEVA 812

                          490       500       510
                   ....*....|....*....|....*....|....
gi 1370459521  680 LRSEQQKATEKERVAQEKDQLQEQLQaLKESLKV 713
Cdd:pfam15921  813 LDKASLQFAECQDIIQRQEQESVRLK-LQHTLDV 845
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1226-1688 5.23e-06

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 51.69  E-value: 5.23e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1226 LISSLEEEV-SILNRQVLEKEGESKELKRLVMAESEKSQKLEERLRLLQ--AETASNSARAAERSSALREEVQSLREEAE 1302
Cdd:COG4717     47 LLERLEKEAdELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEelEELEEELEELEAELEELREELEKLEKLLQ 126

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1303 KQRVASE--NLRQELTSQAERAEELGQELKAWQEKFFQKEQALSTLQLEHTSTQALVSELLPAKHlcqQLQAEQAAAEKR 1380
Cdd:COG4717    127 LLPLYQEleALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATE---EELQDLAEELEE 203

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1381 HREELEQSKQAAGGLRAELLRAQRELGELIPLRQKVAEQERTaQQLRAEKASYAEQLSMLKKAHGLLAEENRGLGERANL 1460
Cdd:COG4717    204 LQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERL-KEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLV 282

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1461 GRQFLEVELDQAREKYVQELAAVRADAETRLAEVQREAQSTARELEVMTAKYEGAKVKVLEERQrfqEERQKLTAQVEQL 1540
Cdd:COG4717    283 LGLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRI---EELQELLREAEEL 359

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1541 EvfQREQTKQVEELSKKLADSDQASKVQQQKLKAVQAQggesqqEAQRLQAQLNELQAQLSQKEQAAEHYKLQMEKAkth 1620
Cdd:COG4717    360 E--EELQLEELEQEIAALLAEAGVEDEEELRAALEQAE------EYQELKEELEELEEQLEELLGELEELLEALDEE--- 428

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1621 ydakkQQNQELQEQLRSLEQLQKENKELRAEAERLGHELQQAGLKTK--EAEQTCRHLTAQVRSLEAQVA 1688
Cdd:COG4717    429 -----ELEEELEELEEELEELEEELEELREELAELEAELEQLEEDGElaELLQELEELKAELRELAEEWA 493
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1022-1661 7.15e-06

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 51.51  E-value: 7.15e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1022 LEKAARAELEMRLQNALNEQRVEFATLQEALAHALTEKEG----KDQELAKLRGLEAAQIKELEELRQTVKQLKEQLAKK 1097
Cdd:pfam02463  159 EEEAAGSRLKRKKKEALKKLIEETENLAELIIDLEELKLQelklKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEER 238

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1098 EKEhasgsgaqseaagrtepTGPKLEALRAEVSKLEQQCQKQQEQADSLERSLEAERASRAERDSALETLQGQLEEKAQE 1177
Cdd:pfam02463  239 IDL-----------------LQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSE 301

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1178 LGHSQSALASAQRELAAFRTKVQDHSKAEDEWKAQVARGRQEAERKNSLISSLEEEVSILNRQVLEKEGESKELKRLVMA 1257
Cdd:pfam02463  302 LLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKL 381

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1258 ESEKSQKLEERLRLLQAETASNSARAAERSSALREEVQSLREEAEKQRVASENLRQELTSQAERAEELGQELKAWQEKFF 1337
Cdd:pfam02463  382 ESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLL 461

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1338 QKEQALSTLQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKRHREELE----QSKQAAGGLRAELLRAQRELGELIPLR 1413
Cdd:pfam02463  462 KDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKvllaLIKDGVGGRIISAHGRLGDLGVAVENY 541

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1414 QKVAEQERTAQQLRAEKASYAEQ-----LSMLKKAHGLLAEENRGLGERANLGRQFLEVELDQAREKYVQELAAVRADAE 1488
Cdd:pfam02463  542 KVAISTAVIVEVSATADEVEERQklvraLTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKR 621

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1489 TRLAEVQREAQ----------------STARELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVEQL---EVFQREQTK 1549
Cdd:pfam02463  622 AKVVEGILKDTeltklkesakakesglRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELakeEILRRQLEI 701

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1550 QVEELSKKLADSDQASKVQQQKLKAVQAQGGESQQEAQRLQAQLNELQAQL---SQKEQAAEHYKLQMEKAKTHYDAKKQ 1626
Cdd:pfam02463  702 KKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEeksRLKKEEKEEEKSELSLKEKELAEERE 781

                          650       660       670
                   ....*....|....*....|....*....|....*
gi 1370459521 1627 QNQELQEQLRSLEQLQKENKELRAEAERLGHELQQ 1661
Cdd:pfam02463  782 KTEKLKVEEEKEEKLKAQEEELRALEEELKEEAEL 816
mukB PRK04863
chromosome partition protein MukB;
831-1703 7.93e-06

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 51.50  E-value: 7.93e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  831 FQEQLMTLKEECEKARQELQEAKEKVAGI-ESHSELQisrQQNELAELHANLARALQQVQEKEVRAQklaDDLSTLQEKM 909
Cdd:PRK04863   291 LRRELYTSRRQLAAEQYRLVEMARELAELnEAESDLE---QDYQAASDHLNLVQTALRQQEKIERYQ---ADLEELEERL 364

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  910 AATSKEVARLETLVRKAGEQQETASRELVKEPARAGDRQpEWLEEQQGR--QFcstQAALQAMEReaeqmGNELERLRAA 987
Cdd:PRK04863   365 EEQNEVVEEADEQQEENEARAEAAEEEVDELKSQLADYQ-QALDVQQTRaiQY---QQAVQALER-----AKQLCGLPDL 435

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  988 LMESqgqqqeergqqerevARLTQERGRAQADLALEKAARAELEMRLQNALNEQRVEFATLQEALAHALTEKEGKDQELA 1067
Cdd:PRK04863   436 TADN---------------AEDWLEEFQAKEQEATEELLSLEQKLSVAQAAHSQFEQAYQLVRKIAGEVSRSEAWDVARE 500

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1068 KLRGLEAAQIkeleeLRQTVKQLKEQLAKKEKEHASGSGAQ------SEAAGRTEPTGPKLEALRAEvskleqqcqkqqe 1141
Cdd:PRK04863   501 LLRRLREQRH-----LAEQLQQLRMRLSELEQRLRQQQRAErllaefCKRLGKNLDDEDELEQLQEE------------- 562

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1142 qADSLERSLEAERASRAERDSALETLQGQLEEKAQELghsqSALASAQRELAAFRTKVQDHSKAEDEWKAQVARGRQeae 1221
Cdd:PRK04863   563 -LEARLESLSESVSEARERRMALRQQLEQLQARIQRL----AARAPAWLAAQDALARLREQSGEEFEDSQDVTEYMQ--- 634

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1222 rknslissleeevsilnrQVLEKEGESKELKRLVmaESEKSQKLEERLRLLQAETASNS--ARAAERSSA-----LREEV 1294
Cdd:PRK04863   635 ------------------QLLERERELTVERDEL--AARKQALDEEIERLSQPGGSEDPrlNALAERFGGvllseIYDDV 694

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1295 qSLrEEAEKQRVASENLRQELtsqaeraeeLGQELKAWQEKFFQKEQALSTLQLEHTSTQALVSELLPAKHLCQQLQAEQ 1374
Cdd:PRK04863   695 -SL-EDAPYFSALYGPARHAI---------VVPDLSDAAEQLAGLEDCPEDLYLIEGDPDSFDDSVFSVEELEKAVVVKI 763

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1375 AAAEKRHRE--ELEQSKQAAGGLRAELLRAQREL--GELIPLRQKVAEQERTAQQLRAEKASYAeQLSMLKKAHGLLAEE 1450
Cdd:PRK04863   764 ADRQWRYSRfpEVPLFGRAAREKRIEQLRAEREElaERYATLSFDVQKLQRLHQAFSRFIGSHL-AVAFEADPEAELRQL 842

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1451 NRGLGEranlgrqfLEVELDQAREKYVQELAAVRAdAETRLAEVQR-EAQSTARELEVMTAKYEG--AKVKVLEERQRFQ 1527
Cdd:PRK04863   843 NRRRVE--------LERALADHESQEQQQRSQLEQ-AKEGLSALNRlLPRLNLLADETLADRVEEirEQLDEAEEAKRFV 913

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1528 EERQKLTAQVEQLEVFQREQTKQVEELSKKLADSDQASKVQQQKLKA----VQAQGGESQQEAQRL---QAQLNE-LQAQ 1599
Cdd:PRK04863   914 QQHGNALAQLEPIVSVLQSDPEQFEQLKQDYQQAQQTQRDAKQQAFAltevVQRRAHFSYEDAAEMlakNSDLNEkLRQR 993

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1600 LSQKEQAAEHYKLQMEKAKTHYDAKKQQNQELQEQLRSLEQLQKENKE----------------LRAEAERLGHELQQAG 1663
Cdd:PRK04863   994 LEQAEQERTRAREQLRQAQAQLAQYNQVLASLKSSYDAKRQMLQELKQelqdlgvpadsgaeerARARRDELHARLSANR 1073

                          890       900       910       920
                   ....*....|....*....|....*....|....*....|
gi 1370459521 1664 LKTKEAEQTCRHLTAQVRSLEAQVAHADQQLRDLGKFQVA 1703
Cdd:PRK04863  1074 SRRNQLEKQLTFCEAEMDNLTKKLRKLERDYHEMREQVVN 1113
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1078-1308 7.94e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 50.53  E-value: 7.94e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1078 KELEELRQTVKQLKEQLAKKEKEHASGSGAQSEAAGRTEPTGPKLEALRAEVSKLEQQCQKQQEQADSLERSLEAERASR 1157
Cdd:COG4942     27 AELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEEL 106

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1158 AERDSALETLQGQleEKAQELGHSQSALASAQRelaafrtkVQDHSKAEDEWKAQVARGRQEAERKNSLISSLEEEVSIL 1237
Cdd:COG4942    107 AELLRALYRLGRQ--PPLALLLSPEDFLDAVRR--------LQYLKYLAPARREQAEELRADLAELAALRAELEAERAEL 176

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1370459521 1238 NRQVLEKEGESKELKRLVMAESEKSQKLEERLRLLQAETASNSARAAErssaLREEVQSLREEAEKQRVAS 1308
Cdd:COG4942    177 EALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEE----LEALIARLEAEAAAAAERT 243
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
592-1086 8.14e-06

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 50.92  E-value: 8.14e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  592 REASLRERDAALKQLEALEkEKAAKLEILQQQLQVANEARDSAQTSVTQAQREKAELSRKVE--ELQACVETARQEQHEA 669
Cdd:COG4717     66 PELNLKELKELEEELKEAE-EKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQllPLYQELEALEAELAEL 144

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  670 QAQVAELELQLRSEQQKATEKERVAQEKDQLQEQLQALKESLKVTKgslEEEKRRAADALEEQQRCISELKAETRSLVEQ 749
Cdd:COG4717    145 PERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLAT---EEELQDLAEELEELQQRLAELEEELEEAQEE 221

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  750 HKRerkeleeeragrkgLEARLQQLGEAHQAETEVLRRELAEAMAAQHTAeseceqlVKEVAAWRERYEDSQQEEAQYGA 829
Cdd:COG4717    222 LEE--------------LEEELEQLENELEAAALEERLKEARLLLLIAAA-------LLALLGLGGSLLSLILTIAGVLF 280

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  830 MFQEQLMTLKEECEKARQELQEAKEKVAGIESHSELQISRQQNELAELHANLARALQQVQEKEVRAQKLADDLSTLQEKm 909
Cdd:COG4717    281 LVLGLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEEL- 359

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  910 aatsKEVARLETLVRKAGEQQETASRELVKEPARAGDRQPEWLEEQQGRQFCSTQAALQAMEREAEQMGNELERLRAALm 989
Cdd:COG4717    360 ----EEELQLEELEQEIAALLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEELEEEL- 434

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  990 esqgqqqeergqqerevARLTQERGRAQADLALEKAARAELEMRLQNALNEQRVefATLQEALAHALTEKEGKDQELAKL 1069
Cdd:COG4717    435 -----------------EELEEELEELEEELEELREELAELEAELEQLEEDGEL--AELLQELEELKAELRELAEEWAAL 495

                          490
                   ....*....|....*..
gi 1370459521 1070 RGLEAAQIKELEELRQT 1086
Cdd:COG4717    496 KLALELLEEAREEYREE 512
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 1380-1686 8.22e-06

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 51.49  E-value: 8.22e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1380 RHREELEQSKQAAGGLRAELLRAQRELGE----LIPLRQKVAEQERTAQQLRAEKASYAEQLSMLKKAhgllaeenrgLG 1455
Cdd:COG3096    275 RHANERRELSERALELRRELFGARRQLAEeqyrLVEMARELEELSARESDLEQDYQAASDHLNLVQTA----------LR 344

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1456 ERANLGRqfLEVELDQAREKyVQELAAVRADAETRLAEvqREAQSTARELEVMTAKYEGAKVK-VLEERQR----FQEER 1530
Cdd:COG3096    345 QQEKIER--YQEDLEELTER-LEEQEEVVEEAAEQLAE--AEARLEAAEEEVDSLKSQLADYQqALDVQQTraiqYQQAV 419

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1531 QKL-----------------TAQVEQLEVFQREQTKQVEELSKKLADSDQASKVQQQKLKAVQAQGGE-----SQQEAQR 1588
Cdd:COG3096    420 QALekaralcglpdltpenaEDYLAAFRAKEQQATEEVLELEQKLSVADAARRQFEKAYELVCKIAGEversqAWQTARE 499

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1589 LQAQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQELQEQLRSL---EQLQKENKELRAEAERLGHELQQAGLK 1665
Cdd:COG3096    500 LLRRYRSQQALAQRLQQLRAQLAELEQRLRQQQNAERLLEEFCQRIGQQLdaaEELEELLAELEAQLEELEEQAAEAVEQ 579

                          330       340
                   ....*....|....*....|.
gi 1370459521 1666 TKEAEQTCRHLTAQVRSLEAQ 1686
Cdd:COG3096    580 RSELRQQLEQLRARIKELAAR 600
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
213-734 8.80e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 51.07  E-value: 8.80e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  213 QFQMRRLKKQLADERSNRDELELELAENRKLLTEKDAQIAMMQQRI-----DRLALLNEKQAASPLEPKELEELRDKNES 287
Cdd:COG4913    287 QRRLELLEAELEELRAELARLEAELERLEARLDALREELDELEAQIrgnggDRLEQLEREIERLERELEERERRRARLEA 366

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  288 LTMRLHETLKqcqdlkTEKSQMDRKINQLSEEngdlsfkLREFASHLQQLQDALNELTEEHSKATQEwlekQAQLEKELS 367
Cdd:COG4913    367 LLAALGLPLP------ASAEEFAALRAEAAAL-------LEALEEELEALEEALAEAEAALRDLRRE----LRELEAEIA 429

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  368 AALQDKKCLEEKNEILqgkLSQLEEHLSQLQDNPPqekgeVLGDVLQLETL-----------------------KQEAAT 424
Cdd:COG4913    430 SLERRKSNIPARLLAL---RDALAEALGLDEAELP-----FVGELIEVRPEeerwrgaiervlggfaltllvppEHYAAA 501

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  425 LAA-NNTQLQARVEMLETERGQQEAKLLAerghFEEekqqlSSLITDLQSSISNLSQ-AKEELEQASQAHGARLTAQVA- 501
Cdd:COG4913    502 LRWvNRLHLRGRLVYERVRTGLPDPERPR----LDP-----DSLAGKLDFKPHPFRAwLEAELGRRFDYVCVDSPEELRr 572

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  502 ---SLTSE-LTTLNATIQQQDQELAG-----LKQQAKEKQAQLAQTLQQqeqasqgLRHQVEQLSSSLKQKEQQLKEVAE 572
Cdd:COG4913    573 hprAITRAgQVKGNGTRHEKDDRRRIrsryvLGFDNRAKLAALEAELAE-------LEEELAEAEERLEALEAELDALQE 645

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  573 KQEATRQdhAQQLATAAEEREASLRERDAALKQLEALEKEKaAKLEILQQQLQVANEARDsaqtsvtQAQREKAELSRKV 652
Cdd:COG4913    646 RREALQR--LAEYSWDEIDVASAEREIAELEAELERLDASS-DDLAALEEQLEELEAELE-------ELEEELDELKGEI 715

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  653 EELQACVETARQEQHEAQAQVAELELQLRSEQQKATEKERVAQEKDQLQEQLQA-LKESLKvtkgSLEEEKRRAADALEE 731
Cdd:COG4913    716 GRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGDAVERELREnLEERID----ALRARLNRAEEELER 791


                   ...
gi 1370459521  732 QQR 734
Cdd:COG4913    792 AMR 794
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
422-642 1.13e-05

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 50.79  E-value: 1.13e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  422 AATLAANNTQLQARVEMLETERGQQEAKLLAERGHFEE--EKQQLSSLITDLQSSISNLSQAKEELEQAsQAHGARLTAQ 499
Cdd:COG3206    163 EQNLELRREEARKALEFLEEQLPELRKELEEAEAALEEfrQKNGLVDLSEEAKLLLQQLSELESQLAEA-RAELAEAEAR 241

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  500 VASLTSELTTLNATIQQ--QDQELAGLKQQAKEKQAQLAQTLQQQEQAS---QGLRHQVEQLSSSLKQKEQQLKEVAEKQ 574
Cdd:COG3206    242 LAALRAQLGSGPDALPEllQSPVIQQLRAQLAELEAELAELSARYTPNHpdvIALRAQIAALRAQLQQEAQRILASLEAE 321

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1370459521  575 EATRQDHAQQLATAAEEREASLRERDAALKQLEALEKEKAAKLEILQQQLQVANEARDSAQTSVTQAQ 642
Cdd:COG3206    322 LEALQAREASLQAQLAQLEARLAELPELEAELRRLEREVEVARELYESLLQRLEEARLAEALTVGNVR 389
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 276-507 1.28e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 49.76  E-value: 1.28e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  276 KELEELRDKNESLTMRLHETLKQCQDLKTEKSQMDRKINQLSEengdlsfKLREFASHLQQLQDALNELTEEHSKATQEW 355
Cdd:COG4942     27 AELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALAR-------RIRALEQELAALEAELAELEKEIAELRAEL 99

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  356 LEKQAQLEKELSAALQDKKCLEEKNEILQGKLSQLEEHLSQLQDNPPQEKGevlgdvlQLETLKQEAATLAANNTQLQAR 435
Cdd:COG4942    100 EAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARRE-------QAEELRADLAELAALRAELEAE 172

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1370459521  436 VEMLETERGQQEakllAERGHFEEEKQQLSSLITDLQSSISNLSQAKEELEQASQahgaRLTAQVASLTSEL 507
Cdd:COG4942    173 RAELEALLAELE----EERAALEALKAERQKLLARLEKELAELAAELAELQQEAE----ELEALIARLEAEA 236
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 210-780 1.54e-05

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 50.17  E-value: 1.54e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  210 QTPQFQMRRLKKQLADERSNRDELELELAENR--KLLTEKDAQIAMMQQRIDRLALLNEKQAASPLEPKELEELRDKNES 287
Cdd:pfam01576    3 QEEEMQAKEEELQKVKERQQKAESELKELEKKhqQLCEEKNALQEQLQAETELCAEAEEMRARLAARKQELEEILHELES 82

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  288 ltmRLHETLKQCQDLKTEKSQMDRKI----NQLSEENG---DLSFKLREFASHLQQLQDALNELTEEHSKATQEwlekQA 360
Cdd:pfam01576   83 ---RLEEEEERSQQLQNEKKKMQQHIqdleEQLDEEEAarqKLQLEKVTTEAKIKKLEEDILLLEDQNSKLSKE----RK 155

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  361 QLEKELSAALQDKKCLEEKNEILQGKLSQLEEHLSQLQDNPPQEKGEVLGDVLQLETLKQEAATLAANNTQLQARVEMLE 440
Cdd:pfam01576  156 LLEERISEFTSNLAEEEEKAKSLSKLKNKHEAMISDLEERLKKEEKGRQELEKAKRKLEGESTDLQEQIAELQAQIAELR 235

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  441 TERGQQEAKLLAERGHFEEEKQQLSSLITDLQSSISNLSQAKEELEQASQAHgARLTAQVASLTSELTTLNATIQQQDQE 520
Cdd:pfam01576  236 AQLAKKEEELQAALARLEEETAQKNNALKKIRELEAQISELQEDLESERAAR-NKAEKQRRDLGEELEALKTELEDTLDT 314

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  521 LAglkqqakekqaqlaqtlqqqeqASQGLRHQVEQLSSSLKQKEQQLKEVAEKQ-EATRQDHAQQLATAAEEREASLRER 599
Cdd:pfam01576  315 TA----------------------AQQELRSKREQEVTELKKALEEETRSHEAQlQEMRQKHTQALEELTEQLEQAKRNK 372

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  600 DAALKQLEALEKEKA---AKLEILQQQLQVANEARDSA-------QTSVTQAQREKAELSRKVEELQACVETARQEQHEA 669
Cdd:pfam01576  373 ANLEKAKQALESENAelqAELRTLQQAKQDSEHKRKKLegqlqelQARLSESERQRAELAEKLSKLQSELESVSSLLNEA 452

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  670 QAQVAELELQLRSEQQKATEKERVAQEKDQLQEQLQALKESLKVTKGSLEEEKRRAADALEEQQRCISELKAETRSLVEQ 749
Cdd:pfam01576  453 EGKNIKLSKDVSSLESQLQDTQELLQEETRQKLNLSTRLRQLEDERNSLQEQLEEEEEAKRNVERQLSTLQAQLSDMKKK 532

                          570       580       590
                   ....*....|....*....|....*....|....*
gi 1370459521  750 HKRERKELEEERAGRK----GLEARLQQLGEAHQA 780
Cdd:pfam01576  533 LEEDAGTLEALEEGKKrlqrELEALTQQLEEKAAA 567
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
894-1553 1.56e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 50.30  E-value: 1.56e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  894 RAQKLADDLSTLQEKMAATSKEVARLETLVRKAGEQQETASRELVKEPARAGdrqpewleeqqgrqfcstqAALQAMERE 973
Cdd:COG4913    229 ALVEHFDDLERAHEALEDAREQIELLEPIRELAERYAAARERLAELEYLRAA-------------------LRLWFAQRR 289

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  974 AEQMGNELERLRAALmesqgqqqeergqqerevARLTQERGRAQADLALEKAARAELEMRLQNALNEQRVEFATLQEALA 1053
Cdd:COG4913    290 LELLEAELEELRAEL------------------ARLEAELERLEARLDALREELDELEAQIRGNGGDRLEQLEREIERLE 351

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1054 HALTEKEGKDQELAK-LRGLEAAQIKELEELRQTVKQLKEQLAKKEKEHASGSGAQSEAAGRteptgpkLEALRAEvskl 1132
Cdd:COG4913    352 RELEERERRRARLEAlLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAA-------LRDLRRE---- 420

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1133 eqqcqkqqeqadslERSLEAERASRAERDSAL-ETLQGQLEEKAQELGHSQSAL-----------------ASAQRELAA 1194
Cdd:COG4913    421 --------------LRELEAEIASLERRKSNIpARLLALRDALAEALGLDEAELpfvgelievrpeeerwrGAIERVLGG 486

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1195 FRTK--VqdhskaEDEWKAQVAR------------------GRQEAERKNSLISSLEEEVSI--------LNRQVLEKEG 1246
Cdd:COG4913    487 FALTllV------PPEHYAAALRwvnrlhlrgrlvyervrtGLPDPERPRLDPDSLAGKLDFkphpfrawLEAELGRRFD 560

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1247 ----ES-KELKRLVMAESEKSQ-KLEERLRLLQAETASNSA-----RAAERSSALREEVQSLREEAEkqrvASENLRQEL 1315
Cdd:COG4913    561 yvcvDSpEELRRHPRAITRAGQvKGNGTRHEKDDRRRIRSRyvlgfDNRAKLAALEAELAELEEELA----EAEERLEAL 636

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1316 TSQAERAEELGQELKAWQEKFFQkeqalstlQLEHTSTQALVSELlpakhlcqqlqaeqaaaeKRHREELEQSKQAAGGL 1395
Cdd:COG4913    637 EAELDALQERREALQRLAEYSWD--------EIDVASAEREIAEL------------------EAELERLDASSDDLAAL 690

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1396 RAELLRAQRELGElipLRQKVAEQERTAQQLRAEKASYAEQLSMLKKAHGlLAEENRGLGERANLGRQFLEVELDQAREK 1475
Cdd:COG4913    691 EEQLEELEAELEE---LEEELDELKGEIGRLEKELEQAEEELDELQDRLE-AAEDLARLELRALLEERFAAALGDAVERE 766

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1370459521 1476 yvqelaaVRADAETRLAEVQREAQSTARELEVMTAKYegakvkvleeRQRFQEERQKLTAQVEQLEVFQREQTKQVEE 1553
Cdd:COG4913    767 -------LRENLEERIDALRARLNRAEEELERAMRAF----------NREWPAETADLDADLESLPEYLALLDRLEED 827
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 304-931 1.81e-05

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 50.02  E-value: 1.81e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  304 TEKSQMDRKINQLSEE-------NGDLSFKLREFASHLQQLQDALNELTEEHSKATQEWLEKQAQLEKELSAALQDKKCL 376
Cdd:TIGR04523   33 TEEKQLEKKLKTIKNElknkekeLKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDLSKINSEI 112

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  377 EEKNEILQGKLSQLEEHLSQLQDNPPQEKgEVLGDVLQLEtlkQEAATLAANNTQLQARVEMLETERGQqeakllaergh 456
Cdd:TIGR04523  113 KNDKEQKNKLEVELNKLEKQKKENKKNID-KFLTEIKKKE---KELEKLNNKYNDLKKQKEELENELNL----------- 177

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  457 FEEEKQQLSSLITDLQSSISNLSQAKEELEQASQAHgARLTAQVASLTSELTTLNATIQQQDQELAGLKQQAKEKQAQLA 536
Cdd:TIGR04523  178 LEKEKLNIQKNIDKIKNKLLKLELLLSNLKKKIQKN-KSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLN 256

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  537 QTLQQQEQASQGLRH---QVEQLSSSLKQKEQQLKEVAEKQEATRQDHAQQLataaeereaslrerdaaLKQLEALEKEK 613
Cdd:TIGR04523  257 QLKDEQNKIKKQLSEkqkELEQNNKKIKELEKQLNQLKSEISDLNNQKEQDW-----------------NKELKSELKNQ 319

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  614 AAKLEILQQQLQVANEARDSAQTSVTQAQREK-------AELSRKVEELQACVETARQEQHEAQAQVAELELQLRSEQQK 686
Cdd:TIGR04523  320 EKKLEEIQNQISQNNKIISQLNEQISQLKKELtnsesenSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESK 399

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  687 ATEKERVAQEKDQLQEQLQALKESLKVTKGSLEEEKRRAADALEEQQRCISELKAETRSLVEQHKRERKELEEERAGRKG 766
Cdd:TIGR04523  400 IQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINK 479

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  767 LEARLQQLgeahQAETEVLRRELAEAMAAQHTAESECEQLVKEVAAWRERYEDSQQEEAQygamFQEQLMTLKEECEKAR 846
Cdd:TIGR04523  480 IKQNLEQK----QKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKE----KESKISDLEDELNKDD 551

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  847 QELQeakekvagiESHSELQISRQQNELAELHANLARALQQVQEKEVRAQKLADDLSTLQEKMAATSKEVARLETLVRKA 926
Cdd:TIGR04523  552 FELK---------KENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKELEKA 622


                   ....*
gi 1370459521  927 GEQQE 931
Cdd:TIGR04523  623 KKENE 627
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 208-784 1.88e-05

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 49.97  E-value: 1.88e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  208 ILQTPQFQMRRLKKQLAdERSNRDELELELAENRKLLTEKDAQIAMMQQRIDRLALLNEKQAASPLEPKELEELRDKNES 287
Cdd:TIGR00618  312 IHTELQSKMRSRAKLLM-KRAAHVKQQSSIEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQHTLTQHIHTLQQQKTT 390

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  288 LTMRLHETLKQCQDLKTEKSQMDRKINQLSEENGDLSFKLREFASHLQQLQDALNELTEEHSKATQE--WLEKQAQLEKE 365
Cdd:TIGR00618  391 LTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEkiHLQESAQSLKE 470

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  366 LSAALQDKKCLEEKNEilqgKLSQLEEHLSQLQDNPPQEKGEVLGDVLQLETLKQEAATLAANNTQLQARVEMLETERGQ 445
Cdd:TIGR00618  471 REQQLQTKEQIHLQET----RKKAVVLARLLELQEEPCPLCGSCIHPNPARQDIDNPGPLTRRMQRGEQTYAQLETSEED 546

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  446 QEAKLLAERGHFEEEKQQLSSLITDLQSSISNLSQAKEELEQASQahgarltaqvasLTSELTTLNATIQQQDQELAGLK 525
Cdd:TIGR00618  547 VYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQN------------ITVRLQDLTEKLSEAEDMLACEQ 614

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  526 QQAKEKQAQLAQTLQQQEQASQglrhqveqlssslKQKEQQLKEVAEKQEAT---RQDHAQQLATAAEEREASLRERDAA 602
Cdd:TIGR00618  615 HALLRKLQPEQDLQDVRLHLQQ-------------CSQELALKLTALHALQLtltQERVREHALSIRVLPKELLASRQLA 681

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  603 LKQLEALEKEKAAKLEILQQQLQVANEARDSAQTSVTQAQREKAELSRKVEELQACVETARQEQHEAQAQV--------- 673
Cdd:TIGR00618  682 LQKMQSEKEQLTYWKEMLAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQArtvlkarte 761

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  674 --AELELQLRSEQQKATEKERVAQEKDQLQEQLQALKESLKVTKGSLEEEKRRAADALEEQQRCISELKAETRSLVEQHK 751
Cdd:TIGR00618  762 ahFNNNEEVTAALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQCETLVQEEEQFLSRLEEKS 841

                          570       580       590
                   ....*....|....*....|....*....|...
gi 1370459521  752 RERKELEEERagrKGLEARLQQLGEAHQAETEV 784
Cdd:TIGR00618  842 ATLGEITHQL---LKYEECSKQLAQLTQEQAKI 871
EmrA COG1566
Multidrug resistance efflux pump EmrA [Defense mechanisms];
590-715 1.89e-05

Multidrug resistance efflux pump EmrA [Defense mechanisms];


Pssm-ID: 441174 [Multi-domain]  Cd Length: 331  Bit Score: 49.28  E-value: 1.89e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  590 EEREASLRERDAALKQLEAlEKEKAAKLEILQQQLQVANEARDSAQTSVTQAQREKAELSR----------KVEELQACV 659
Cdd:COG1566     79 TDLQAALAQAEAQLAAAEA-QLARLEAELGAEAEIAAAEAQLAAAQAQLDLAQRELERYQAlykkgavsqqELDEARAAL 157

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1370459521  660 ETARQEQHEAQAQVAELELQLRSEQQKATEKERVAqekdQLQEQLQALKESLKVTK 715
Cdd:COG1566    158 DAAQAQLEAAQAQLAQAQAGLREEEELAAAQAQVA----QAEAALAQAELNLARTT 209
PRK10929 PRK10929
putative mechanosensitive channel protein; Provisional
 777-1198 1.98e-05

putative mechanosensitive channel protein; Provisional


Pssm-ID: 236798 [Multi-domain]  Cd Length: 1109  Bit Score: 50.05  E-value: 1.98e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  777 AHQAETEVLRRELAEAMAAQHTAESECEQLVKEVAAWRERYEDSQQEEAQYgamfQEQLMTLKEECEKARQELQEAKEKV 856
Cdd:PRK10929    20 ATAPDEKQITQELEQAKAAKTPAQAEIVEALQSALNWLEERKGSLERAKQY----QQVIDNFPKLSAELRQQLNNERDEP 95

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  857 AGIESHSE--------LQISRQQNElaelhanLARALQQVQEkevRAQKLADDLSTLQekmaatskevarletlvrkagE 928
Cdd:PRK10929    96 RSVPPNMStdaleqeiLQVSSQLLE-------KSRQAQQEQD---RAREISDSLSQLP---------------------Q 144

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  929 QQETASRELVKEPARAGDR-QPEWLEEQQgrQFCSTQAALQAMEREAEQMgnELERLRaalmesqgqqqeergqqerevA 1007
Cdd:PRK10929   145 QQTEARRQLNEIERRLQTLgTPNTPLAQA--QLTALQAESAALKALVDEL--ELAQLS---------------------A 199

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1008 RLTQERGRAQADLALEKAARAELEMR-LQNALNEQRVEFAtlQEALAHA--LTEKEGK-----DQELAKLRGLEAA---Q 1076
Cdd:PRK10929   200 NNRQELARLRSELAKKRSQQLDAYLQaLRNQLNSQRQREA--ERALESTelLAEQSGDlpksiVAQFKINRELSQAlnqQ 277

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1077 IKELEEL----RQTVKQLKE--QLAKKEKEHASGSGAqSEAAGrteptgpklEALRAEVSKLEQQCQKQQeqadsLERSL 1150
Cdd:PRK10929   278 AQRMDLIasqqRQAASQTLQvrQALNTLREQSQWLGV-SNALG---------EALRAQVARLPEMPKPQQ-----LDTEM 342

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1151 EAERASRAERDSALETLQgQLEEKAQELGhsqSALASAQREL--AAFRTK 1198
Cdd:PRK10929   343 AQLRVQRLRYEDLLNKQP-QLRQIRQADG---QPLTAEQNRIldAQLRTQ 388
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 1248-1663 2.18e-05

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 49.95  E-value: 2.18e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1248 SKELKRLVMAESEKSQKLE---ERLRLLQaetasNSARAAERSSALREEVQSLREEAEKQRVASENLRQELTSQAERAEE 1324
Cdd:COG3096    312 ARELEELSARESDLEQDYQaasDHLNLVQ-----TALRQQEKIERYQEDLEELTERLEEQEEVVEEAAEQLAEAEARLEA 386

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1325 LGQELKAWQEKFFQKEQALSTLQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKRHREELEQSKQAAGGLRAellraqr 1404
Cdd:COG3096    387 AEEEVDSLKSQLADYQQALDVQQTRAIQYQQAVQALEKARALCGLPDLTPENAEDYLAAFRAKEQQATEEVLE------- 459

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1405 elgelipLRQKVAEQERTAQQlraekasYAEQLSMLKKAHGLLAEENRGLGERANLgRQFLEVELDQARekyVQELAAVR 1484
Cdd:COG3096    460 -------LEQKLSVADAARRQ-------FEKAYELVCKIAGEVERSQAWQTARELL-RRYRSQQALAQR---LQQLRAQL 521

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1485 ADAETRLAEvQREAQSTARELEvmtakyegakvkvleerQRFQEERQkltaQVEQLEVFQREQTKQVEELSKKLADSDQA 1564
Cdd:COG3096    522 AELEQRLRQ-QQNAERLLEEFC-----------------QRIGQQLD----AAEELEELLAELEAQLEELEEQAAEAVEQ 579

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1565 SKVQQQKLKAVQAQGGESQQEAQR---LQAQLNELQAQLSQKEQAAEHYKLQMEKAKTHydakkqqnqelqeqLRSLEQL 1641
Cdd:COG3096    580 RSELRQQLEQLRARIKELAARAPAwlaAQDALERLREQSGEALADSQEVTAAMQQLLER--------------EREATVE 645

                          410       420
                   ....*....|....*....|..
gi 1370459521 1642 QKENKELRAEAERLGHELQQAG 1663
Cdd:COG3096    646 RDELAARKQALESQIERLSQPG 667
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
318-991 2.20e-05

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 49.68  E-value: 2.20e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  318 EENGDLSFKLREFASHLQQLQ-DALNELTEEHSKATQEWLEKQAQLEKELSAALqdkkcleekneILQGKLSQLeehlsq 396
Cdd:PRK03918    78 EKNGRKYRIVRSFNRGESYLKyLDGSEVLEEGDSSVREWVERLIPYHVFLNAIY-----------IRQGEIDAI------ 140

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  397 LQDNPPQEKgeVLGDVLQLETLKQEAATLAANNTQLQARVEMLETERGQQE--AKLLAERGHFEEEKQQ----LSSLITD 470
Cdd:PRK03918   141 LESDESREK--VVRQILGLDDYENAYKNLGEVIKEIKRRIERLEKFIKRTEniEELIKEKEKELEEVLReineISSELPE 218

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  471 LQSSISNLSQAKEELEqASQAHGARLTAQVASLTSELTTLNATIQQQDQELAGLKQQAKEKQAQLAQTLQQQEQASQGLR 550
Cdd:PRK03918   219 LREELEKLEKEVKELE-ELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKEKAEEYIK 297

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  551 hqVEQLSSSLKQKEQQLKEVAEKQEatrqdhaqQLATAAEEREASLRERDAALKQLEALEKEKAAKLEILQQQLQVANEA 630
Cdd:PRK03918   298 --LSEFYEEYLDELREIEKRLSRLE--------EEINGIEERIKELEEKEERLEELKKKLKELEKRLEELEERHELYEEA 367

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  631 RdsaqTSVTQAQREKAELS-RKVEELQACVETARQEQHEAQAQVAELELQLRSEQQKATEKERVAQEkdqlqeqLQALKE 709
Cdd:PRK03918   368 K----AKKEELERLKKRLTgLTPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEE-------LKKAKG 436

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  710 SLKVTKGSLEEEKRraADALEEQQRCISELKAETRSLVEQHKRERKELEEERAGRKGLEARLQQLGEAHQAETevLRREL 789
Cdd:PRK03918   437 KCPVCGRELTEEHR--KELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKLKELAEQLKE--LEEKL 512

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  790 AEAMAAQHTAESECEQLVKEVAAWRERYEDSQQEEAQYGAMFQEQLMTLKEECEKARQELQEAKEKVAGIESHSELQISR 869
Cdd:PRK03918   513 KKYNLEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEE 592

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  870 QQNELAELHA---NLARALQQVQEKEVRAQKLADDLSTLQEKMAATSKEV----ARLETLVRKAGEQQETASRELVKEPA 942
Cdd:PRK03918   593 RLKELEPFYNeylELKDAEKELEREEKELKKLEEELDKAFEELAETEKRLeelrKELEELEKKYSEEEYEELREEYLELS 672

                          650       660       670       680
                   ....*....|....*....|....*....|....*....|....*....
gi 1370459521  943 RAGDRQPEWLEEQQGRqfcstqaaLQAMEREAEQMGNELERLRAALMES 991
Cdd:PRK03918   673 RELAGLRAELEELEKR--------REEIKKTLEKLKEELEEREKAKKEL 713
PRK10246 PRK10246
exonuclease subunit SbcC; Provisional
 204-654 2.28e-05

exonuclease subunit SbcC; Provisional


Pssm-ID: 182330 [Multi-domain]  Cd Length: 1047  Bit Score: 49.80  E-value: 2.28e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  204 PMGDILQTPQFQMRRLKKQLADERSNRDELELELAENRKLLTEKDAQIAMMQQRIDRLALLNEKQAasplEPKELEELRD 283
Cdd:PRK10246   423 PLRQRLVALHGQIVPQQKRLAQLQVAIQNVTQEQTQRNAALNEMRQRYKEKTQQLADVKTICEQEA----RIKDLEAQRA 498

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  284 KNES------LTMRLHETLKQCQDLKTEKSQ-----MDRKINQLSEENGDLSFKLREFASHLQQLQDALNELTEEHSKAT 352
Cdd:PRK10246   499 QLQAgqpcplCGSTSHPAVEAYQALEPGVNQsrldaLEKEVKKLGEEGAALRGQLDALTKQLQRDESEAQSLRQEEQALT 578

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  353 QEWLEKQAQLEKELSAALQDKKCLEEKNEILQgKLSQL-EEHLSQLQDNPPQEKgevlgdVLQLEtlKQEAATLAANNTQ 431
Cdd:PRK10246   579 QQWQAVCASLNITLQPQDDIQPWLDAQEEHER-QLRLLsQRHELQGQIAAHNQQ------IIQYQ--QQIEQRQQQLLTA 649

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  432 LQARVEMLETErgQQEAKLLAERGHFEEEKQQLSSLITDLQSSISNLSQAKEELEQ--ASQAHGARLTA--------QVA 501
Cdd:PRK10246   650 LAGYALTLPQE--DEEASWLATRQQEAQSWQQRQNELTALQNRIQQLTPLLETLPQsdDLPHSEETVALdnwrqvheQCL 727

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  502 SLTSELTTLNATIQQQDQELAGLKQQ---AKEKQAQLAQTLQQQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEATR 578
Cdd:PRK10246   728 SLHSQLQTLQQQDVLEAQRLQKAQAQfdtALQASVFDDQQAFLAALLDEETLTQLEQLKQNLENQRQQAQTLVTQTAQAL 807

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1370459521  579 QDHaQQLATAAEEREASLRERDAALKQLEALEKEKAAKLEILQQQLQVANEARDSAQTSVTQAqrekAELSRKVEE 654
Cdd:PRK10246   808 AQH-QQHRPDGLDLTVTVEQIQQELAQLAQQLRENTTRQGEIRQQLKQDADNRQQQQALMQQI----AQATQQVED 878
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 1227-1670 2.43e-05

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 49.72  E-value: 2.43e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1227 ISSLEEEVSILNRQVLEKEGESKELKRLVMAESEKSQKLEERLRLlqaeTASNSARAAERSSALREEVQSLREEAEKQRV 1306
Cdd:pfam05483  235 INDKEKQVSLLLIQITEKENKMKDLTFLLEESRDKANQLEEKTKL----QDENLKELIEKKDHLTKELEDIKMSLQRSMS 310

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1307 ASENLRQELTSQAERAEELGQELKAWQEKFFQKEQALSTLQLEHTSTQALVSELLpakhlcqqlqaeqaaaeKRHREELE 1386
Cdd:pfam05483  311 TQKALEEDLQIATKTICQLTEEKEAQMEELNKAKAAHSFVVTEFEATTCSLEELL-----------------RTEQQRLE 373

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1387 QSKQAAGGLRAELLRAQRELGELIPLRQKVAEQERTAQQLRAEKasyaEQLSMLKKAHGLLAEENRGLGERAnlgrqfle 1466
Cdd:pfam05483  374 KNEDQLKIITMELQKKSSELEEMTKFKNNKEVELEELKKILAED----EKLLDEKKQFEKIAEELKGKEQEL-------- 441

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1467 VELDQAREKYVQELaavradaETRLAEVQREAQSTARELEVMTAKYEGAKVKVLEerqrfqeerqkLTAQVEQLEVFQRE 1546
Cdd:pfam05483  442 IFLLQAREKEIHDL-------EIQLTAIKTSEEHYLKEVEDLKTELEKEKLKNIE-----------LTAHCDKLLLENKE 503

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1547 QTKQ----VEELSKKLADSDQASKVQQQKLKAVQAQGGESQQEAQRLQA-------QLNELQAQLSQKEQAAEHYKLQME 1615
Cdd:pfam05483  504 LTQEasdmTLELKKHQEDIINCKKQEERMLKQIENLEEKEMNLRDELESvreefiqKGDEVKCKLDKSEENARSIEYEVL 583

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1370459521 1616 KAKTHYDAKKQQ----NQELQEQLRSLEQLQKENKELRAEAERLGHELQQAGLKTKEAE 1670
Cdd:pfam05483  584 KKEKQMKILENKcnnlKKQIENKNKNIEELHQENKALKKKGSAENKQLNAYEIKVNKLE 642
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
1198-1325 2.64e-05

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 49.47  E-value: 2.64e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1198 KVQDHSKAEDEWKAQVARGRQEAERknsliSSLEEEVSILNRQVLEKEGESKELKRLVMAESEKSQKLEERLRLLQAEtA 1277
Cdd:COG2433    384 ELIEKELPEEEPEAEREKEHEEREL-----TEEEEEIRRLEEQVERLEAEVEELEAELEEKDERIERLERELSEARSE-E 457

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*...
gi 1370459521 1278 SNSARAAERSSALREEVQSLREEAEKQRVASENLRQELtsqaERAEEL 1325
Cdd:COG2433    458 RREIRKDREISRLDREIERLERELEEERERIEELKRKL----ERLKEL 501
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
230-681 4.14e-05

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 48.88  E-value: 4.14e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  230 RDELELELAENRKLLTEKDAQIAMMQQRIDRLAllnekQAASPLEpKELEELRDKNESLTMRLHETLKQCQDLKTEKSQM 309
Cdd:PRK02224   316 REELEDRDEELRDRLEECRVAAQAHNEEAESLR-----EDADDLE-ERAEELREEAAELESELEEAREAVEDRREEIEEL 389

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  310 DRKINQLSEENGDLSFKLREFASHLQQLQDALNELTEEhskatqewlekqaqlEKELSAALQDKKCLEEKNEILQ--GKL 387
Cdd:PRK02224   390 EEEIEELRERFGDAPVDLGNAEDFLEELREERDELRER---------------EAELEATLRTARERVEEAEALLeaGKC 454

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  388 SQLEEhlsQLQDNPpqekgevlgDVLQLETLKQEAATLAANNTQLQARVEMLET--ERGQQEAKLLAERGHFEEEKQQLS 465
Cdd:PRK02224   455 PECGQ---PVEGSP---------HVETIEEDRERVEELEAELEDLEEEVEEVEErlERAEDLVEAEDRIERLEERREDLE 522

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  466 SLITDLQSSISNLSQAKEEL-----EQASQAHGARLTAQVASLTSE-----LTTLNATIQQQDQELAGLkqqakEKQAQL 535
Cdd:PRK02224   523 ELIAERRETIEEKRERAEELreraaELEAEAEEKREAAAEAEEEAEeareeVAELNSKLAELKERIESL-----ERIRTL 597

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  536 AQTLQQQEQASQGLRHQVEQLSSSLKQKEQQLKEvaekqeatRQDHAQQLATAAEEreaslrerdAALKQLEALEKEKAA 615
Cdd:PRK02224   598 LAAIADAEDEIERLREKREALAELNDERRERLAE--------KRERKRELEAEFDE---------ARIEEAREDKERAEE 660

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1370459521  616 KLEILQQQLQVANEARDSAQTSVTQAQREKAELSRKVEELQAC------VETARQEQHEAQAQVAELELQLR 681
Cdd:PRK02224   661 YLEQVEEKLDELREERDDLQAEIGAVENELEELEELRERREALenrveaLEALYDEAEELESMYGDLRAELR 732
mukB PRK04863
chromosome partition protein MukB;
1277-1687 4.17e-05

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 49.19  E-value: 4.17e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1277 ASNSARAAERSSALREEVQSLREE---AEKQRVASEN----LRQELTSQAERAEELGQELKAWQEKfFQKEQALSTLQLE 1349
Cdd:PRK04863   271 AADYMRHANERRVHLEEALELRRElytSRRQLAAEQYrlveMARELAELNEAESDLEQDYQAASDH-LNLVQTALRQQEK 349

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1350 HTSTQALVSELLPAKHLCQQLQAEQAAAEKRHREELEQSKQAAGGLRAELLRAQRELGELiplrQKVAEQERTAQQL--R 1427
Cdd:PRK04863   350 IERYQADLEELEERLEEQNEVVEEADEQQEENEARAEAAEEEVDELKSQLADYQQALDVQ----QTRAIQYQQAVQAleR 425

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1428 AEKASYAEQLSmLKKAHGLLAE---ENRGLGERANLGRQFLEVElDQAREKYVQELAAVRADAetrlAEVQR-EAQSTAR 1503
Cdd:PRK04863   426 AKQLCGLPDLT-ADNAEDWLEEfqaKEQEATEELLSLEQKLSVA-QAAHSQFEQAYQLVRKIA----GEVSRsEAWDVAR 499

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1504 ELEvmtakyegakvKVLEERQRFQEERQKLTAQVEQLEVFQREQTKQVEELskkladsDQASKVQQQKLKAVQaqggESQ 1583
Cdd:PRK04863   500 ELL-----------RRLREQRHLAEQLQQLRMRLSELEQRLRQQQRAERLL-------AEFCKRLGKNLDDED----ELE 557

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1584 QEAQRLQAQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQELQEQLRSLEQLQKENKELRAEAERLGHELQQAG 1663
Cdd:PRK04863   558 QLQEELEARLESLSESVSEARERRMALRQQLEQLQARIQRLAARAPAWLAAQDALARLREQSGEEFEDSQDVTEYMQQLL 637

                          410       420
                   ....*....|....*....|....
gi 1370459521 1664 LKTKEAEQTCRHLTAQVRSLEAQV 1687
Cdd:PRK04863   638 ERERELTVERDELAARKQALDEEI 661
mukB PRK04863
chromosome partition protein MukB;
431-791 4.46e-05

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 48.80  E-value: 4.46e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  431 QLQARVEMLETERGQQEAKLLAERGHFEEEKQQLSSL--------ITDLQSSISNLSQAKEELEQASQAhgARLTAQVAS 502
Cdd:PRK04863   841 QLNRRRVELERALADHESQEQQQRSQLEQAKEGLSALnrllprlnLLADETLADRVEEIREQLDEAEEA--KRFVQQHGN 918

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  503 LTSELTTLNATIQQQDQELAGLKQQAKekqaqlaqtlqqqeqasqglrhQVEQLSSSLKQKEQQLKEVAEKQEATRQDHA 582
Cdd:PRK04863   919 ALAQLEPIVSVLQSDPEQFEQLKQDYQ----------------------QAQQTQRDAKQQAFALTEVVQRRAHFSYEDA 976

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  583 QQLATAAEEREASLRERdaaLKQLEalekekaakleilqqqlqvanEARDSAQTSVTQAQREKAELSRKVEELQACVETA 662
Cdd:PRK04863   977 AEMLAKNSDLNEKLRQR---LEQAE---------------------QERTRAREQLRQAQAQLAQYNQVLASLKSSYDAK 1032

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  663 RQEQHEAQAQVAELELQLRSEqqkatEKERVAQEKDQLQEQL---QALKESLKVTKGSLEEEKRRAADALEEQQRCISEL 739
Cdd:PRK04863  1033 RQMLQELKQELQDLGVPADSG-----AEERARARRDELHARLsanRSRRNQLEKQLTFCEAEMDNLTKKLRKLERDYHEM 1107

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1370459521  740 kaetRSLVEQHkrerkeleeeragrKGLEARLQQLGEAHQAETEVLRRELAE 791
Cdd:PRK04863  1108 ----REQVVNA--------------KAGWCAVLRLVKDNGVERRLHRRELAY 1141
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 264-948 4.58e-05

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 48.56  E-value: 4.58e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  264 LNEKQAASPLEPKELEELRDKNESLTMRLHETLKQCQDLKTEKSQMDRKINQLSEENGDLSFKLREFASHLQQLQDALNE 343
Cdd:pfam05483  108 LQENRKIIEAQRKAIQELQFENEKVSLKLEEEIQENKDLIKENNATRHLCNLLKETCARSAEKTKKYEYEREETRQVYMD 187

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  344 LTEEHSKATQEWLEKQAQLEK---ELSAAL-QDKKCLEEKNEILQGKLSQLEEHLSQLQDNPPQEKGEVLGDVLQLETLK 419
Cdd:pfam05483  188 LNNNIEKMILAFEELRVQAENarlEMHFKLkEDHEKIQHLEEEYKKEINDKEKQVSLLLIQITEKENKMKDLTFLLEESR 267

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  420 QEAATLAANNTQLQARVEMLETERGQQEAKLLAERGHFEEEKQQLSSLITDLQSSISNLSQAKEELE-QASQAHGARLTA 498
Cdd:pfam05483  268 DKANQLEEKTKLQDENLKELIEKKDHLTKELEDIKMSLQRSMSTQKALEEDLQIATKTICQLTEEKEaQMEELNKAKAAH 347

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  499 QVasLTSELTTLNATIqqqdQELAGLKQQAKEKQAQLAQTLQQQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEaTR 578
Cdd:pfam05483  348 SF--VVTEFEATTCSL----EELLRTEQQRLEKNEDQLKIITMELQKKSSELEEMTKFKNNKEVELEELKKILAEDE-KL 420

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  579 QDHAQQLATAAEEREASLRErdaalkqLEALEKEKAAKLEILQQQLQVANEARDSAQTSVTQAQREKAELSRKVEELQAC 658
Cdd:pfam05483  421 LDEKKQFEKIAEELKGKEQE-------LIFLLQAREKEIHDLEIQLTAIKTSEEHYLKEVEDLKTELEKEKLKNIELTAH 493

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  659 VETARQEQHEAQAQVAELELQLRSEQQK----ATEKERVAQEKDQLQEQLQALKESLKVTKGSLEEEKRRAADALEEQQR 734
Cdd:pfam05483  494 CDKLLLENKELTQEASDMTLELKKHQEDiincKKQEERMLKQIENLEEKEMNLRDELESVREEFIQKGDEVKCKLDKSEE 573

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  735 CISELKAETRSLVEQHKRERKELEEEragRKGLEARLQQLGEAHQaETEVLRRELAEAMAAQHTAESECEQLVKEVAAWR 814
Cdd:pfam05483  574 NARSIEYEVLKKEKQMKILENKCNNL---KKQIENKNKNIEELHQ-ENKALKKKGSAENKQLNAYEIKVNKLELELASAK 649

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  815 ERYE---DSQQEEAQYGAMFQEQLMtlkEECEKARQELQEAKEKVAGIESHSELQISrQQNELAELHANLARALQQVQEK 891
Cdd:pfam05483  650 QKFEeiiDNYQKEIEDKKISEEKLL---EEVEKAKAIADEAVKLQKEIDKRCQHKIA-EMVALMEKHKHQYDKIIEERDS 725

                          650       660       670       680       690       700
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1370459521  892 EV-----RAQKLADDLSTLQEKMAATSKEVARLETLVRKAGEQQETASRELVKEPARAGDRQ 948
Cdd:pfam05483  726 ELglyknKEQEQSSAKAALEIELSNIKAELLSLKKQLEIEKEEKEKLKMEAKENTAILKDKK 787
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 649-1608 4.66e-05

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 48.63  E-value: 4.66e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  649 SRKVEELQAcvetARQEQHEAQAQVAELELQLRSEQQKATEkerVAQEKDQLQEQLQALKE----------SLKVTKGSL 718
Cdd:pfam01576    1 TRQEEEMQA----KEEELQKVKERQQKAESELKELEKKHQQ---LCEEKNALQEQLQAETElcaeaeemraRLAARKQEL 73

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  719 EEEKRRAADALEEQQRCISELKAETRSLVEQHKRERKELEEERAGRKGLE---ARLQQLGEAHQAETEVLRRELAEAMAA 795
Cdd:pfam01576   74 EEILHELESRLEEEEERSQQLQNEKKKMQQHIQDLEEQLDEEEAARQKLQlekVTTEAKIKKLEEDILLLEDQNSKLSKE 153

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  796 QHTAESECEQLVKEVAAWRERYEDSQQEEAQYGAMFQEQLMTLKEEcEKARQELQEAKEKVAGIESHSELQISRQQNELA 875
Cdd:pfam01576  154 RKLLEERISEFTSNLAEEEEKAKSLSKLKNKHEAMISDLEERLKKE-EKGRQELEKAKRKLEGESTDLQEQIAELQAQIA 232

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  876 ELHANLARALQQVQEKEVRAQK--------------LADDLSTLQEKMAATSKEVARLETLVRKAGEQQETASREL---- 937
Cdd:pfam01576  233 ELRAQLAKKEEELQAALARLEEetaqknnalkkireLEAQISELQEDLESERAARNKAEKQRRDLGEELEALKTELedtl 312

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  938 ----------------VKEPARAGDRQPEWLEEQQGRQFCSTQAALQAMEREAEQmgneLERLRAALMESQGQQQEERGQ 1001
Cdd:pfam01576  313 dttaaqqelrskreqeVTELKKALEEETRSHEAQLQEMRQKHTQALEELTEQLEQ----AKRNKANLEKAKQALESENAE 388

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1002 QEREVARLTQ-----ERGRAQADLAL-EKAARAELEMRLQNALNEQRVEFATLQEALAHALTEKEGKDQELAKLRGLEAA 1075
Cdd:pfam01576  389 LQAELRTLQQakqdsEHKRKKLEGQLqELQARLSESERQRAELAEKLSKLQSELESVSSLLNEAEGKNIKLSKDVSSLES 468

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1076 QIKELEELRQTVKQLKEQLAKK----EKEHASGSGAQSEAAGRTEPTGPKLEALRAEVSKLEQQCQKQQEQADSLE---- 1147
Cdd:pfam01576  469 QLQDTQELLQEETRQKLNLSTRlrqlEDERNSLQEQLEEEEEAKRNVERQLSTLQAQLSDMKKKLEEDAGTLEALEegkk 548

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1148 ---RSLEAERASRAERDSALETLQGQLEEKAQELGHSQSALASAQRELAAFRTKVQDHSKAEDEWKAQVARGRQEAERKN 1224
Cdd:pfam01576  549 rlqRELEALTQQLEEKAAAYDKLEKTKNRLQQELDDLLVDLDHQRQLVSNLEKKQKKFDQMLAEEKAISARYAEERDRAE 628

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1225 SLISSLEEEVSILNRQVLEKEGESKELKRlvmaeSEKSQKLEERLRLLQAETASNSARAAERSS-ALREEVQSLR---EE 1300
Cdd:pfam01576  629 AEAREKETRALSLARALEEALEAKEELER-----TNKQLRAEMEDLVSSKDDVGKNVHELERSKrALEQQVEEMKtqlEE 703

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1301 AEKQRVASEN--LRQELTSQAERA---------EELGQELK------------AWQEKFFQKEQALST---LQLEHTSTQ 1354
Cdd:pfam01576  704 LEDELQATEDakLRLEVNMQALKAqferdlqarDEQGEEKRrqlvkqvreleaELEDERKQRAQAVAAkkkLELDLKELE 783

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1355 ALVSELLPAKHLCQQLQAEQAAAEKRHREELEQSKQAAGGLRAELLRAQREL----GELIPLRQKVAEQERTAQQLRAEK 1430
Cdd:pfam01576  784 AQIDAANKGREEAVKQLKKLQAQMKDLQRELEEARASRDEILAQSKESEKKLknleAELLQLQEDLAASERARRQAQQER 863

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1431 ASYAEQLSMLKKAHGLLAEENRGLGERANLGRQFLEVE-------------LDQAREKYVQELAAVRADAETRLAEVQR- 1496
Cdd:pfam01576  864 DELADEIASGASGKSALQDEKRRLEARIAQLEEELEEEqsntellndrlrkSTLQVEQLTTELAAERSTSQKSESARQQl 943

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1497 ------------EAQSTARELEVMTAKYEGAKVKVLEER-QRFQEERQKLTAQVEQLEVFQREQTKQVEElSKKLADS-- 1561
Cdd:pfam01576  944 erqnkelkaklqEMEGTVKSKFKSSIAALEAKIAQLEEQlEQESRERQAANKLVRRTEKKLKEVLLQVED-ERRHADQyk 1022

                         1050      1060      1070      1080
                   ....*....|....*....|....*....|....*....|....*..
gi 1370459521 1562 DQASKVqQQKLKAVQAQGGESQQEAQRLQAQLNELQAQLSQKEQAAE 1608
Cdd:pfam01576 1023 DQAEKG-NSRMKQLKRQLEEAEEEASRANAARRKLQRELDDATESNE 1068
PLN02939 PLN02939
transferase, transferring glycosyl groups
 251-494 6.53e-05

transferase, transferring glycosyl groups


Pssm-ID: 215507 [Multi-domain]  Cd Length: 977  Bit Score: 48.36  E-value: 6.53e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  251 IAMMQQRIDRLALLNEK--QAASPLEP--KELEELRDKNESLTMRLHETLKQCQDLKTEKSQMDRKINQLSEENGDLSFK 326
Cdd:PLN02939   134 VGMIQNAEKNILLLNQArlQALEDLEKilTEKEALQGKINILEMRLSETDARIKLAAQEKIHVEILEEQLEKLRNELLIR 213

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  327 LREFASHLQQLQDALNELTEEHS--KATQEWL-----------EKQAQLEKE---LSAALQDkkcLEEKNEILQGKLSQl 390
Cdd:PLN02939   214 GATEGLCVHSLSKELDVLKEENMllKDDIQFLkaelievaeteERVFKLEKErslLDASLRE---LESKFIVAQEDVSK- 289

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  391 eehLSQLQDNPPQEKGEVLGDVLQLETLKQE-AATLAANNTQLQARVEMLETERG---------------QQEAKLLAEr 454
Cdd:PLN02939   290 ---LSPLQYDCWWEKVENLQDLLDRATNQVEkAALVLDQNQDLRDKVDKLEASLKeanvskfssykvellQQKLKLLEE- 365

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....
gi 1370459521  455 gHFEEEKQQLSSLITDLQSSIS----NLSQAKEELEQASQAHGA 494
Cdd:PLN02939   366 -RLQASDHEIHSYIQLYQESIKefqdTLSKLKEESKKRSLEHPA 408
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 378-604 6.74e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.45  E-value: 6.74e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  378 EKNEILQGKLSQLEEHLSQLQDNPPQEKGEVLGDVLQLETLKQEAATLAANNTQLQARVEMLETERGQQEAKLLAERGHF 457
Cdd:COG4942     20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAEL 99

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  458 EEEKQQLSSLITDLQ--------------SSISNLSQAKEELEQASQAHGARLTAQVASLTsELTTLNATIQQQDQELAG 523
Cdd:COG4942    100 EAQKEELAELLRALYrlgrqpplalllspEDFLDAVRRLQYLKYLAPARREQAEELRADLA-ELAALRAELEAERAELEA 178

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  524 LKQQAKEKQAQLAQTLQQQEQasqglrhQVEQLSSSLKQKEQQLKEVAEKQEATRQDHAQQLATAAEEREASLRERDAAL 603
Cdd:COG4942    179 LLAELEEERAALEALKAERQK-------LLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAGFAAL 251


                   .
gi 1370459521  604 K 604
Cdd:COG4942    252 K 252
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 554-1351 6.97e-05

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 48.19  E-value: 6.97e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  554 EQLSSSLKQKEQQLKEVAEKQEATRQDHaqqlataaEEREASLRERDAALK-QLEALEKEKAAKLEILQQQLQVANEARD 632
Cdd:pfam15921   74 EHIERVLEEYSHQVKDLQRRLNESNELH--------EKQKFYLRQSVIDLQtKLQEMQMERDAMADIRRRESQSQEDLRN 145

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  633 SAQTSVTQAQREKAELSRKVEELQACVETARQEQHEAQAQVAELELQLRSEQQKATEK--ERVAQEKDQLQEQLQALKES 710
Cdd:pfam15921  146 QLQNTVHELEAAKCLKEDMLEDSNTQIEQLRKMMLSHEGVLQEIRSILVDFEEASGKKiyEHDSMSTMHFRSLGSAISKI 225

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  711 LKVTKGSLEEEKRRAADALEEQQRCISELKAETRSLVEQHkrerkeleeeragrkglEARLQQLGEAHQAETEVLRRELA 790
Cdd:pfam15921  226 LRELDTEISYLKGRIFPVEDQLEALKSESQNKIELLLQQH-----------------QDRIEQLISEHEVEITGLTEKAS 288

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  791 EAMAAQHTAESECEQLvkevaawreryedsQQEEAQYGAMFQEQLMTLKEECEKARQELQEAKEKVAGIESHSELQISRQ 870
Cdd:pfam15921  289 SARSQANSIQSQLEII--------------QEQARNQNSMYMRQLSDLESTVSQLRSELREAKRMYEDKIEELEKQLVLA 354

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  871 QNELAELHANLARALQQVQEKEVRAQKLADDLSTLQEKMAATSKEVARL-------ETLVRKAGEQQETASRELVKEPAR 943
Cdd:pfam15921  355 NSELTEARTERDQFSQESGNLDDQLQKLLADLHKREKELSLEKEQNKRLwdrdtgnSITIDHLRRELDDRNMEVQRLEAL 434

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  944 AGDRQPEwLEEQQGRQFCSTQAALQAMEREAE---QMGNELERLRaALMESQGQQQEERGQQEREVARLT---QERGRA- 1016
Cdd:pfam15921  435 LKAMKSE-CQGQMERQMAAIQGKNESLEKVSSltaQLESTKEMLR-KVVEELTAKKMTLESSERTVSDLTaslQEKERAi 512

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1017 QADLALEKAARAELEMRLQnalneQRVEFATLQEALAHALTEKEGkdqelakLRGLEAAQIKELEELRQTVKQLKEQLAK 1096
Cdd:pfam15921  513 EATNAEITKLRSRVDLKLQ-----ELQHLKNEGDHLRNVQTECEA-------LKLQMAEKDKVIEILRQQIENMTQLVGQ 580

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1097 KEKehASGSGAQSEAAGRTEPTGPKLEALRAEVSKLEQQCQKQQEQADSLERSLEAERASRA--ERDSALETLQGQLEEK 1174
Cdd:pfam15921  581 HGR--TAGAMQVEKAQLEKEINDRRLELQEFKILKDKKDAKIRELEARVSDLELEKVKLVNAgsERLRAVKDIKQERDQL 658

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1175 AQELGHSQSALASAQRELAA----FRTKVQDHSKAEDEWKAQVARGRQEAERKNSLISSLEE------EVSI-LNRQVLE 1243
Cdd:pfam15921  659 LNEVKTSRNELNSLSEDYEVlkrnFRNKSEEMETTTNKLKMQLKSAQSELEQTRNTLKSMEGsdghamKVAMgMQKQITA 738

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1244 KEGESKELKRLVMAESEKSQKLEERLRLLQAEtasnSARAAERSSALREEVQSLREEAEKQRVASENLRQELTSQAERAE 1323
Cdd:pfam15921  739 KRGQIDALQSKIQFLEEAMTNANKEKHFLKEE----KNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANMEVALD 814

                          810       820
                   ....*....|....*....|....*...
gi 1370459521 1324 ELGQELKAWQEKFFQKEQALSTLQLEHT 1351
Cdd:pfam15921  815 KASLQFAECQDIIQRQEQESVRLKLQHT 842
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 645-1662 7.35e-05

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 48.25  E-value: 7.35e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  645 KAELSRKVEELQACVETARQEQHEAQAQVAELELQLRSEQQKATEKERVAQE-KDQLQEQLQALKESLKVTKGSLEEEKR 723
Cdd:pfam01576   10 KEEELQKVKERQQKAESELKELEKKHQQLCEEKNALQEQLQAETELCAEAEEmRARLAARKQELEEILHELESRLEEEEE 89

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  724 RAADALEEQQRCISELKAETRSLVEQHKRERK---ELEEERAGRKGLEARLQQLgEAHQAETEVLRRELAEAMAAQHTAE 800
Cdd:pfam01576   90 RSQQLQNEKKKMQQHIQDLEEQLDEEEAARQKlqlEKVTTEAKIKKLEEDILLL-EDQNSKLSKERKLLEERISEFTSNL 168

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  801 SECEQLVKEVAAWRERYEdsqqeeaqygAMFQEQLMTLKEEcEKARQELQEAKEKVAGIESHSELQISRQQNELAELHAN 880
Cdd:pfam01576  169 AEEEEKAKSLSKLKNKHE----------AMISDLEERLKKE-EKGRQELEKAKRKLEGESTDLQEQIAELQAQIAELRAQ 237

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  881 LARALQQVQEKEVRAQK--------------LADDLSTLQEKMAATSKEVARLETLVRKAGEQQETASREL--------- 937
Cdd:pfam01576  238 LAKKEEELQAALARLEEetaqknnalkkireLEAQISELQEDLESERAARNKAEKQRRDLGEELEALKTELedtldttaa 317

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  938 -----------VKEPARAGDRQPEWLEEQQGRQFCSTQAALQAMEREAEQmgneLERLRAALMESQGQQQEERGQQEREV 1006
Cdd:pfam01576  318 qqelrskreqeVTELKKALEEETRSHEAQLQEMRQKHTQALEELTEQLEQ----AKRNKANLEKAKQALESENAELQAEL 393

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1007 ARLTQ-----ERGRAQADLAL-EKAARAELEMRLQNALNEQRVEFATLQEALAHALTEKEGKDQELAKLRGLEAAQIKEL 1080
Cdd:pfam01576  394 RTLQQakqdsEHKRKKLEGQLqELQARLSESERQRAELAEKLSKLQSELESVSSLLNEAEGKNIKLSKDVSSLESQLQDT 473

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1081 EELRQTVKQLKEQLAKK----EKEHASGSGAQSEAAGRTEPTGPKLEALRAEVSKLEQQCQKQQEQADSLE-------RS 1149
Cdd:pfam01576  474 QELLQEETRQKLNLSTRlrqlEDERNSLQEQLEEEEEAKRNVERQLSTLQAQLSDMKKKLEEDAGTLEALEegkkrlqRE 553

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1150 LEAERASRAERDSALETLQGQLEEKAQELGHSQSALASAQRELAAFRTKVQDHSKAEDEWKAQVARGRQEAERKNSLISS 1229
Cdd:pfam01576  554 LEALTQQLEEKAAAYDKLEKTKNRLQQELDDLLVDLDHQRQLVSNLEKKQKKFDQMLAEEKAISARYAEERDRAEAEARE 633

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1230 LEEEVSILNRQVLEKEGESKELKRlvmaeSEKSQKLEERLRLLQAETASNSARAAERSS-ALREEVQSLR---EEAEKQR 1305
Cdd:pfam01576  634 KETRALSLARALEEALEAKEELER-----TNKQLRAEMEDLVSSKDDVGKNVHELERSKrALEQQVEEMKtqlEELEDEL 708

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1306 VASEN--LRQELTSQAERAE---ELGQELKAWQEKFFQKEQALSTLQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKR 1380
Cdd:pfam01576  709 QATEDakLRLEVNMQALKAQferDLQARDEQGEEKRRQLVKQVRELEAELEDERKQRAQAVAAKKKLELDLKELEAQIDA 788

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1381 HREELEQSKQAAGGLRAELLRAQRELGELIPLRQKV----AEQERTAQQLRAEKASYAEQLSMLKKAHGLLAEENRGLGE 1456
Cdd:pfam01576  789 ANKGREEAVKQLKKLQAQMKDLQRELEEARASRDEIlaqsKESEKKLKNLEAELLQLQEDLAASERARRQAQQERDELAD 868

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1457 RANLGRQFLEVELDQAREkyvqeLAAVRADAETRLAEVQREAQSTARELEVMTAKYEGAKVKVLEER---QRFQEERQKL 1533
Cdd:pfam01576  869 EIASGASGKSALQDEKRR-----LEARIAQLEEELEEEQSNTELLNDRLRKSTLQVEQLTTELAAERstsQKSESARQQL 943

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1534 TAQVEQLEVFQREQTKQVEELSKKLADSDQASKVQ-QQKLKAVQAQGGESQQEAQRLQAQLNELQAQLSQKEQAAEHYKL 1612
Cdd:pfam01576  944 ERQNKELKAKLQEMEGTVKSKFKSSIAALEAKIAQlEEQLEQESRERQAANKLVRRTEKKLKEVLLQVEDERRHADQYKD 1023

                         1050      1060      1070      1080      1090
                   ....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1613 QMEKAKTHYDAKKqqnqelqeqlRSLEQLQKENKELRAEAERLGHELQQA 1662
Cdd:pfam01576 1024 QAEKGNSRMKQLK----------RQLEEAEEEASRANAARRKLQRELDDA 1063
Caldesmon pfam02029
Caldesmon;
550-856 7.60e-05

Caldesmon;


Pssm-ID: 460421 [Multi-domain]  Cd Length: 495  Bit Score: 47.55  E-value: 7.60e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  550 RHQVEQLSSSLKQKEQQLKEVAEKQEATRQDHAQQLATAAEEREASL-----RERDAALKQLEALEKEKAAKLEILQQQL 624
Cdd:pfam02029   19 RRRQKEEEEPSGQVTESVEPNEHNSYEEDSELKPSGQGGLDEEEAFLdrtakREERRQKRLQEALERQKEFDPTIADEKE 98

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  625 QVANEARDSAQTSVTQAQREKAELSRKVEELQACVETARQEQHEAQAQVAElelqlRSEQQKATEKERvAQEKDQLQEQL 704
Cdd:pfam02029   99 SVAERKENNEEEENSSWEKEEKRDSRLGRYKEEETEIREKEYQENKWSTEV-----RQAEEEGEEEED-KSEEAEEVPTE 172

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  705 QALKESLKVTKGSLEEEKRRAADALEEQQRCISELKAETR-SLVEQHKRERKELEEERAGRKGLEARLQQLGEAHQAETE 783
Cdd:pfam02029  173 NFAKEEVKDEKIKKEKKVKYESKVFLDQKRGHPEVKSQNGeEEVTKLKVTTKRRQGGLSQSQEREEEAEVFLEAEQKLEE 252

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  784 VLRR-------ELAEAMAAQHTAESECEQLVKEVAAWRERYEDSQ----QEEAQYGAMFQEQLMTLKEECEKARQELQEA 852
Cdd:pfam02029  253 LRRRrqekeseEFEKLRQKQQEAELELEELKKKREERRKLLEEEEqrrkQEEAERKLREEEEKRRMKEEIERRRAEAAEK 332


                   ....
gi 1370459521  853 KEKV 856
Cdd:pfam02029  333 RQKL 336
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1159-1684 8.72e-05

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 47.75  E-value: 8.72e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1159 ERDSALETLQGQLEEKAQELGHSQSALASAQRELAAFRTKVQDHSKAEDEWKAQVARGRQEAERKNSLISSLEEEVSILN 1238
Cdd:PRK03918   186 KRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELE 265

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1239 RQVLEKEGESKELKRLV--MAESEKSQKLEERLRLLQAETASNSARAAERSSALREEVQSLREEAEKQRVASENLRqELT 1316
Cdd:PRK03918   266 ERIEELKKEIEELEEKVkeLKELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLE-ELK 344

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1317 SQAERAEELGQELKAWQEKFFQKEQALSTLQLEHTSTQALVSELLPAKhlcqqlQAEQAAAEKRHREELEQSKQAAGGLR 1396
Cdd:PRK03918   345 KKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLTPEKLEKE------LEELEKAKEEIEEEISKITARIGELK 418

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1397 AELLRAQRELGELIPLRQK--VAEQERTAQQLRAEKASYAEQLSMLKKAHGLLAEENRGLGERANLGRQFLEVE------ 1468
Cdd:PRK03918   419 KEIKELKKAIEELKKAKGKcpVCGRELTEEHRKELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKEselikl 498

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1469 ---LDQARE------KY-VQELAAVRADAET---RLAEVQREAQSTARELEVMTAkYEGAKVKVLEERQRFQEERQKLTA 1535
Cdd:PRK03918   499 kelAEQLKEleeklkKYnLEELEKKAEEYEKlkeKLIKLKGEIKSLKKELEKLEE-LKKKLAELEKKLDELEEELAELLK 577

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1536 QVEQLEVfqreqtKQVEELSKKLADSDQASKvQQQKLKAVQAQGGESQQEAQRLQAQLNELQAQLSQKEQAAEHYKLQME 1615
Cdd:PRK03918   578 ELEELGF------ESVEELEERLKELEPFYN-EYLELKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELE 650

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1370459521 1616 KAKTHYDAKKqqnqelqeqlrsLEQLQKENKELRAEAERLGHELQQAGLKTKEAEQTCRHLTAQVRSLE 1684
Cdd:PRK03918   651 ELEKKYSEEE------------YEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEERE 707
PRK09039 PRK09039
peptidoglycan -binding protein;
866-988 8.75e-05

peptidoglycan -binding protein;


Pssm-ID: 181619 [Multi-domain]  Cd Length: 343  Bit Score: 46.88  E-value: 8.75e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  866 QISRQQNELAELHANLARALQQVQEKEVRAQKLADDLSTLQEKMAATSKEVARLETL-VRKAGEQQETASRELVKEPARA 944
Cdd:PRK09039    47 EISGKDSALDRLNSQIAELADLLSLERQGNQDLQDSVANLRASLSAAEAERSRLQALlAELAGAGAAAEGRAGELAQELD 126

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1370459521  945 --------GDRQPEWLEEQQG---RQFCSTQAALQAMEREAEQMGNELE----RLRAAL 988
Cdd:PRK09039   127 sekqvsarALAQVELLNQQIAalrRQLAALEAALDASEKRDRESQAKIAdlgrRLNVAL 185
46 PHA02562
endonuclease subunit; Provisional
 307-527 8.75e-05

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 47.70  E-value: 8.75e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  307 SQMDR----KINQLSEENGDLSFKLRefasHLQQLQDALNELTEEHSKATQEWL-EKQAQLEKELSAALQDKKCLEEKNE 381
Cdd:PHA02562   166 SEMDKlnkdKIRELNQQIQTLDMKID----HIQQQIKTYNKNIEEQRKKNGENIaRKQNKYDELVEEAKTIKAEIEELTD 241

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  382 ILQGKLSQLE---EHLSQLQDNPPQEKGEVL-----------GDVL-----QLETLKQEAATLAANNTQLQARVEMLETE 442
Cdd:PHA02562   242 ELLNLVMDIEdpsAALNKLNTAAAKIKSKIEqfqkvikmyekGGVCptctqQISEGPDRITKIKDKLKELQHSLEKLDTA 321

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  443 RGQQEAKllaerghfEEEKQQLSSLITDLQSSISNLSQA-KEELEQASQAHGA--RLTAQVASLTSELTTLNATIQQQDQ 519
Cdd:PHA02562   322 IDELEEI--------MDEFNEQSKKLLELKNKISTNKQSlITLVDKAKKVKAAieELQAEFVDNAEELAKLQDELDKIVK 393


                   ....*...
gi 1370459521  520 ELAGLKQQ 527
Cdd:PHA02562   394 TKSELVKE 401
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
607-741 8.83e-05

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 47.55  E-value: 8.83e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  607 EALEKEKAaklEILQQQLQVANEARDSAQTSVTQAQREKAELSRKVEELQACVETARQEQHEAQAQVAELELQLRSEQQK 686
Cdd:COG2433    380 EALEELIE---KELPEEEPEAEREKEHEERELTEEEEEIRRLEEQVERLEAEVEELEAELEEKDERIERLERELSEARSE 456

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1370459521  687 ATEKERVAQEkdqlqeqLQALKESLKVTKGSLEEEKRRaadaLEEQQRCISELKA 741
Cdd:COG2433    457 ERREIRKDRE-------ISRLDREIERLERELEEERER----IEELKRKLERLKE 500
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 300-531 9.87e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.07  E-value: 9.87e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  300 QDLKTEKSQMDRKINQLSEENGDLSFKLREFASHLQQLQDALNELTEEHSKATQEwlekQAQLEKELSAALQDKKCLEEK 379
Cdd:COG4942     23 AEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQE----LAALEAELAELEKEIAELRAE 98

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  380 NEILQGKLSQLeehLSQLQDNPPQEKGEVLgdvLQLETLKQEAATLAANNTQLQARVEMLETERGQQEaKLLAERGHFEE 459
Cdd:COG4942     99 LEAQKEELAEL---LRALYRLGRQPPLALL---LSPEDFLDAVRRLQYLKYLAPARREQAEELRADLA-ELAALRAELEA 171

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1370459521  460 EKQQLSSLITDLQssisnlsQAKEELEQASQAHG---ARLTAQVASLTSELTTLNATIQQQDQELAGLKQQAKEK 531
Cdd:COG4942    172 ERAELEALLAELE-------EERAALEALKAERQkllARLEKELAELAAELAELQQEAEELEALIARLEAEAAAA 239
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
549-720 1.04e-04

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 47.32  E-value: 1.04e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  549 LRHQVEQLSSSLKQKEQQLKEVAEKQ-----EATRQDHAQQLATAAEEREASLRERDAALKQLEALEKEKAAKLEI---- 619
Cdd:COG3206    180 LEEQLPELRKELEEAEAALEEFRQKNglvdlSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLGSGPDAlpel 259

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  620 --------LQQQLQVANEARDSAQT-------SVTQAQREKAELSRKV-EELQACVETARQEQHEAQAQVAELELQLRSE 683
Cdd:COG3206    260 lqspviqqLRAQLAELEAELAELSArytpnhpDVIALRAQIAALRAQLqQEAQRILASLEAELEALQAREASLQAQLAQL 339

                          170       180       190
                   ....*....|....*....|....*....|....*..
gi 1370459521  684 QQKATEKERVAQEKDQLQEQLQALKESLKVTKGSLEE 720
Cdd:COG3206    340 EARLAELPELEAELRRLEREVEVARELYESLLQRLEE 376
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 207-930 1.08e-04

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 47.73  E-value: 1.08e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  207 DILQTPQF--QMRRLKKQLADERSNRDELELELaenRKLLTEKDAQIAMMQQRIDRLALLNEKQAASPLEPKELEELRDK 284
Cdd:TIGR00606  177 EIFSATRYikALETLRQVRQTQGQKVQEHQMEL---KYLKQYKEKACEIRDQITSKEAQLESSREIVKSYENELDPLKNR 253

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  285 NEsltmRLHETLKQCQDLKTEKSQMDRKINQLSEENGDLSFKLREFashLQQLQDALNELTEEHSKATQEWLEKQAQLEK 364
Cdd:TIGR00606  254 LK----EIEHNLSKIMKLDNEIKALKSRKKQMEKDNSELELKMEKV---FQGTDEQLNDLYHNHQRTVREKERELVDCQR 326

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  365 ELSAALQDKKCLEEKNEILQGKLSQLeehlsQLQDNPPQEKgevlgdVLQLETLKQEAATlaanNTQLQARVEMLETERG 444
Cdd:TIGR00606  327 ELEKLNKERRLLNQEKTELLVEQGRL-----QLQADRHQEH------IRARDSLIQSLAT----RLELDGFERGPFSERQ 391

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  445 QQEAKLLAERGHfEEEKQQLSSLITDLQSSISNLSQAKEELEQASQAHGARLTAQVASLTSELTTLNATIQQQDQELAGL 524
Cdd:TIGR00606  392 IKNFHTLVIERQ-EDEAKTAAQLCADLQSKERLKQEQADEIRDEKKGLGRTIELKKEILEKKQEELKFVIKELQQLEGSS 470

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  525 KQQAKekqaqlaqtlqqqeqASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEATRQDHAQQLATAAEEREASLRERDAALK 604
Cdd:TIGR00606  471 DRILE---------------LDQELRKAERELSKAEKNSLTETLKKEVKSLQNEKADLDRKLRKLDQEMEQLNHHTTTRT 535

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  605 QLEALEKEKAAKleilQQQLQVANEARDSAQTSVTQAQREKAELSRKVEELQACVETARQEQHEAQAQVAELEL---QLR 681
Cdd:TIGR00606  536 QMEMLTKDKMDK----DEQIRKIKSRHSDELTSLLGYFPNKKQLEDWLHSKSKEINQTRDRLAKLNKELASLEQnknHIN 611

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  682 SEQQKATEKERVAQEK-------DQLQEQLQALKESLKvtKGSLEEEKRRAADALEEQQrcISELKAETRSLVEQHKRER 754
Cdd:TIGR00606  612 NELESKEEQLSSYEDKlfdvcgsQDEESDLERLKEEIE--KSSKQRAMLAGATAVYSQF--ITQLTDENQSCCPVCQRVF 687

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  755 KELEEERAGRKGLEARLQQLG---EAHQAETEVLRRELAEAMAAQHTAESECEQLVKEVAAWRERYEDSQQEEAQYGAMF 831
Cdd:TIGR00606  688 QTEAELQEFISDLQSKLRLAPdklKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDI 767

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  832 QEQ---LMTLKEECEKARQEL------QEAKEKVAGIESHSELQISRQQNelAELHANLARALQQVQEKEVRAQKLADDL 902
Cdd:TIGR00606  768 EEQetlLGTIMPEEESAKVCLtdvtimERFQMELKDVERKIAQQAAKLQG--SDLDRTVQQVNQEKQEKQHELDTVVSKI 845

                          730       740
                   ....*....|....*....|....*...
gi 1370459521  903 STLQEKMAATSKEVARLETLVRKAGEQQ 930
Cdd:TIGR00606  846 ELNRKLIQDQQEQIQHLKSKTNELKSEK 873
mukB PRK04863
chromosome partition protein MukB;
1276-1655 1.11e-04

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 47.64  E-value: 1.11e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1276 TASNSARAAERSSALREEVQSLREEAEKQRVASENLRQELTSQAERAEELGQELKAWQEKFfQKEQALSTLQLEHTSTQA 1355
Cdd:PRK04863   277 HANERRVHLEEALELRRELYTSRRQLAAEQYRLVEMARELAELNEAESDLEQDYQAASDHL-NLVQTALRQQEKIERYQA 355

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1356 LVSELLPAKHLCQQLQAEQAAAEKRHREELEQSKQAAGGLRAELLRAQRELGELiplrQKVAEQERTAQQL--RAEKASY 1433
Cdd:PRK04863   356 DLEELEERLEEQNEVVEEADEQQEENEARAEAAEEEVDELKSQLADYQQALDVQ----QTRAIQYQQAVQAleRAKQLCG 431

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1434 AEQLSmLKKAHGLLAE---ENRGLGERANLGRQFLEVElDQAREKYVQELAAVRADAetrlAEVQR-EAQSTARELE--- 1506
Cdd:PRK04863   432 LPDLT-ADNAEDWLEEfqaKEQEATEELLSLEQKLSVA-QAAHSQFEQAYQLVRKIA----GEVSRsEAWDVARELLrrl 505

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1507 ----VMTAKYEGAKVKVLEERQRFQEER----------QKLTAQV---EQLEVFQREQTKQVEELSKKLADSDQASKVQQ 1569
Cdd:PRK04863   506 reqrHLAEQLQQLRMRLSELEQRLRQQQraerllaefcKRLGKNLddeDELEQLQEELEARLESLSESVSEARERRMALR 585

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1570 QKLKAVQAQGGESQQEAQR---LQAQLNELQAQLSQKEQAAEHYKLQMekakthydakkqqnQELQEQLRSL----EQLQ 1642
Cdd:PRK04863   586 QQLEQLQARIQRLAARAPAwlaAQDALARLREQSGEEFEDSQDVTEYM--------------QQLLERERELtverDELA 651

                          410
                   ....*....|...
gi 1370459521 1643 KENKELRAEAERL 1655
Cdd:PRK04863   652 ARKQALDEEIERL 664
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1471-1693 1.13e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 46.68  E-value: 1.13e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1471 QAREKYVQELAAVRADAETRLAEVQREAQSTARELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVEQLEVFQREQTKQ 1550
Cdd:COG4942     23 AEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQ 102

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1551 VEELSKKLADSDQASKVQQQKLKAVQAQGGESQQEAQRLQAQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQE 1630
Cdd:COG4942    103 KEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAE 182

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1370459521 1631 LQEQLRSLEQLQKENKELRAEAERLGHELQQAGLKTKEAEQTcrhLTAQVRSLEAQVAHADQQ 1693
Cdd:COG4942    183 LEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEE---LEALIARLEAEAAAAAER 242
PRK09039 PRK09039
peptidoglycan -binding protein;
1045-1201 1.18e-04

peptidoglycan -binding protein;


Pssm-ID: 181619 [Multi-domain]  Cd Length: 343  Bit Score: 46.50  E-value: 1.18e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1045 FATLQEALAHALTekeGKDQELAKLrgleAAQIKELEEL----RQTVKQLKEQLAKkekEHASGSGAQSEAAgrteptgp 1120
Cdd:PRK09039    37 FVVAQFFLSREIS---GKDSALDRL----NSQIAELADLlsleRQGNQDLQDSVAN---LRASLSAAEAERS-------- 98

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1121 KLEALRAEVSkleQQCQKQQEQADSLERSLEAERASRAERDSALETLQGQLEEKAQELGHSQSALASAQRELAAFRTKVQ 1200
Cdd:PRK09039    99 RLQALLAELA---GAGAAAEGRAGELAQELDSEKQVSARALAQVELLNQQIAALRRQLAALEAALDASEKRDRESQAKIA 175


                   .
gi 1370459521 1201 D 1201
Cdd:PRK09039   176 D 176
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 971-1610 1.31e-04

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 47.27  E-value: 1.31e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  971 EREAEQMGNELERLRAALMESQGQQQEERGQQEREVARLTQERGRAQADLALEKAARAELEMRLQNALNEQRVEFATLQE 1050
Cdd:TIGR00618  195 KAELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREALQQTQQSHAYLTQKREAQEEQLKKQQLLKQLRARIEELRA 274

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1051 ALA-HALTEKEGKDQELAKLRGLEAAQIKELEELRQTVKQ-LKEQLAKKEKEHASGSGAQSEAAgRTEPTGPKLEALRAE 1128
Cdd:TIGR00618  275 QEAvLEETQERINRARKAAPLAAHIKAVTQIEQQAQRIHTeLQSKMRSRAKLLMKRAAHVKQQS-SIEEQRRLLQTLHSQ 353

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1129 VSKLEQQCQKQQEQADSLERSLEAERASRAERDSaLETLQGQLEEKAQELGHSQSALASAQRELAAFRTKVQDHSKAEDE 1208
Cdd:TIGR00618  354 EIHIRDAHEVATSIREISCQQHTLTQHIHTLQQQ-KTTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAHAKKQ 432

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1209 WKAQVARGRQEAERKNSLISSLEEEVSILNR---QVLEKEGESKELKRLVMAESEKSQKLEERLRLLQAE----TASNSA 1281
Cdd:TIGR00618  433 QELQQRYAELCAAAITCTAQCEKLEKIHLQEsaqSLKEREQQLQTKEQIHLQETRKKAVVLARLLELQEEpcplCGSCIH 512

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1282 RAAERSSALREEVQSLREEAEKQRVAS-----ENLRQELTSQAERAEELGQELKAWQEKFFQKEQALSTLQLEHTSTQAL 1356
Cdd:TIGR00618  513 PNPARQDIDNPGPLTRRMQRGEQTYAQletseEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNI 592

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1357 VSELLpakHLCQQLQAEQAAAEKRHREELEQSKQAAGGLRAELLRAQRELGELIPLRQKVAEQERTAQQLRAEKASYAEQ 1436
Cdd:TIGR00618  593 TVRLQ---DLTEKLSEAEDMLACEQHALLRKLQPEQDLQDVRLHLQQCSQELALKLTALHALQLTLTQERVREHALSIRV 669

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1437 LSMLKKAHGLLAEE------------NRGLGERANLGRQFLEVELDQAREKYVQELAAVRADAETR-----LAEVQREAQ 1499
Cdd:TIGR00618  670 LPKELLASRQLALQkmqsekeqltywKEMLAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAaredaLNQSLKELM 749

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1500 STARE-------------LEVMTAKYEGAKVKVLE-ERQRFQEERQKLTAQVEQLEVFQREQTK--------QVEELSKK 1557
Cdd:TIGR00618  750 HQARTvlkarteahfnnnEEVTAALQTGAELSHLAaEIQFFNRLREEDTHLLKTLEAEIGQEIPsdedilnlQCETLVQE 829

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1370459521 1558 LADSDQASKVQQQKLKAVQAQGGESQQEAQRLQaQLNELQAQLSQKEQAAEHY 1610
Cdd:TIGR00618  830 EEQFLSRLEEKSATLGEITHQLLKYEECSKQLA-QLTQEQAKIIQLSDKLNGI 881
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1075-1501 1.42e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 47.07  E-value: 1.42e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1075 AQIKELEELRQTVKQLKEQLAKKEKEHASGSGAQSEAAGRTEPTGPKLEA--LRAEVSKLEQQCQKQQEQADSLERSLEA 1152
Cdd:COG4717     78 EELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLlpLYQELEALEAELAELPERLEELEERLEE 157

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1153 ER---ASRAERDSALETLQGQLEEKAQELG-HSQSALASAQRELAAFRTKVQDHSKAEDEWKAQVARGRQEAERKNSLIS 1228
Cdd:COG4717    158 LReleEELEELEAELAELQEELEELLEQLSlATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELE 237

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1229 SLEEEVSIL-NRQVLEKEGESKELKRLVMAESEKSQKLEERLRLLQAETASNSARAAERSSALREEVQSLREEAEKQRVA 1307
Cdd:COG4717    238 AAALEERLKeARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPALEELE 317

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1308 SENLRQELTS-------QAERAEELGQELKAWQEKFFQKEQALSTLQLEHTSTQAlvSELLPAKHLCQQLQAEQAAAEKR 1380
Cdd:COG4717    318 EEELEELLAAlglppdlSPEELLELLDRIEELQELLREAEELEEELQLEELEQEI--AALLAEAGVEDEEELRAALEQAE 395

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1381 HREELEQSKQAAgglrAELLRAQRELGELIPLRQKVAEQERTAQQLRAEKASYAEQLSMLKKAHGLLAEENRGLGERANL 1460
Cdd:COG4717    396 EYQELKEELEEL----EEQLEELLGELEELLEALDEEELEEELEELEEELEELEEELEELREELAELEAELEQLEEDGEL 471

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|.
gi 1370459521 1461 GRQFLEVELDQAREKYVQELAAVRADAETRLAEVQREAQST 1501
Cdd:COG4717    472 AELLQELEELKAELRELAEEWAALKLALELLEEAREEYREE 512
Rab5-bind pfam09311
Rabaptin-like protein; Members of this family are predominantly found in Rabaptin and allow ...
 280-580 2.01e-04

Rabaptin-like protein; Members of this family are predominantly found in Rabaptin and allow for binding to the GTPase Rab5. This interaction is necessary and sufficient for Rab5-dependent recruitment of Rabaptin5 to early endosomal membranes.


Pssm-ID: 462752 [Multi-domain]  Cd Length: 307  Bit Score: 45.73  E-value: 2.01e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  280 ELRDKNESLTMRLHETLKQCQDLKTEKSQMDRKINQLSEENgdlSFKLREFASHLQQLQDALNELTEEHSKATQEWLEKQ 359
Cdd:pfam09311   20 ETRDQVKKLQEMLRQANDQLEKTMKDKKELEDKMNQLSEET---SNQVSTLAKRNQKSETLLDELQQAFSQAKRNFQDQL 96

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  360 AQLEKELSAALQDKKCLEEKNEILQGKLSqleehlsqlqdnppqekgevlgdvLQLETLKQEAATLAANNTQLQARVEML 439
Cdd:pfam09311   97 AVLMDSREQVSDELVRLQKDNESLQGKHS------------------------LHVSLQQAEKFDMPDTVQELQELVLKY 152

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  440 ETErgqqeakLLAERGHFEEEKQQLSSLITDLQSSISNLSQAKEELEQASQAHGARLTAQVASLTSELTTLNATIQQQDQ 519
Cdd:pfam09311  153 REE-------LIEVRTAADHMEEKLKAEILFLKEQIQAEQCLKENLEETLQAEIENCKEEIASISSLKVELERIKAEKEQ 225

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1370459521  520 ELAGLKQQAK--EKQAQLAQTLQQQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEATRQD 580
Cdd:pfam09311  226 LENGLTEKIRqlEDLQTTKGSLETQLKKETNEKAAVEQLVFEEKNKAQRLQTELDVSEQVQRD 288
Cast pfam10174
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ...
 222-741 2.22e-04

RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.


Pssm-ID: 431111 [Multi-domain]  Cd Length: 766  Bit Score: 46.35  E-value: 2.22e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  222 QLADERSNRDELELELAENRKLLT---EKDAQIAMMQQRIDRLALlnekqaasplepkELEELRDKNESLTMRLHETLKQ 298
Cdd:pfam10174  210 HLREELHRRNQLQPDPAKTKALQTvieMKDTKISSLERNIRDLED-------------EVQMLKTNGLLHTEDREEEIKQ 276

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  299 CQDLKTEKSQMDRKINQLSEEngdlsfkLREFASHLQQLQDALNELTEEHSKATQEWlekqAQLEKELSAALQDKKCLEE 378
Cdd:pfam10174  277 MEVYKSHSKFMKNKIDQLKQE-------LSKKESELLALQTKLETLTNQNSDCKQHI----EVLKESLTAKEQRAAILQT 345

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  379 KNEILQGKLSQLEEHLSQLQDnppqekgevlgdvlQLETLKQEAATLAANNTQLQarvEMLETergqQEAKLLAERGHFE 458
Cdd:pfam10174  346 EVDALRLRLEEKESFLNKKTK--------------QLQDLTEEKSTLAGEIRDLK---DMLDV----KERKINVLQKKIE 404

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  459 EEKQQLSslitDLQSSISNLSQAKEELEQASqahgarltaqvASLTSELTTLNATIQQQDQELAGLKQQAKEKQAQLAQT 538
Cdd:pfam10174  405 NLQEQLR----DKDKQLAGLKERVKSLQTDS-----------SNTDTALTTLEEALSEKERIIERLKEQREREDRERLEE 469

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  539 LQQQEQASQGLRHQVEQLSSSLKQKEQQLKEVaekqeatrQDHAQQLATaaeereaSLRERDAALKQLEALEKEKAAKLE 618
Cdd:pfam10174  470 LESLKKENKDLKEKVSALQPELTEKESSLIDL--------KEHASSLAS-------SGLKKDSKLKSLEIAVEQKKEECS 534

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  619 ILQQQLQVANEARDSAQTsvtqaqreKAELSRKVEELQACVETARQEQHEAQAQVAELELQLR-SEQQKATEKERVAQEK 697
Cdd:pfam10174  535 KLENQLKKAHNAEEAVRT--------NPEINDRIRLLEQEVARYKEESGKAQAEVERLLGILReVENEKNDKDKKIAELE 606

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|....
gi 1370459521  698 DQLQEQLQALKESLKVTKGSLEEEKRRAADALEEQQRCISELKA 741
Cdd:pfam10174  607 SLTLRQMKEQNKKVANIKHGQQEMKKKGAQLLEEARRREDNLAD 650
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1151-1361 2.32e-04

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 46.16  E-value: 2.32e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1151 EAERASRAERDSALETLQGQLEEKAQELghsqsalASAQRELAAFRTK-----VQDHSKAEDEwkaQVARGRQEAERKNS 1225
Cdd:COG3206    164 QNLELRREEARKALEFLEEQLPELRKEL-------EEAEAALEEFRQKnglvdLSEEAKLLLQ---QLSELESQLAEARA 233

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1226 LISSLEEEVSILNRQVLEKEGESKELkrlvmAESEKSQKLEERLRLLQAETASNSARAAERSS---ALREEVQSLR---- 1298
Cdd:COG3206    234 ELAEAEARLAALRAQLGSGPDALPEL-----LQSPVIQQLRAQLAELEAELAELSARYTPNHPdviALRAQIAALRaqlq 308

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1370459521 1299 EEAEKQRVASENLRQELTSQAERAEELGQELKAWQEKFFQKEQALSTLQLEHTSTQALVSELL 1361
Cdd:COG3206    309 QEAQRILASLEAELEALQAREASLQAQLAQLEARLAELPELEAELRRLEREVEVARELYESLL 371
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 633-895 2.41e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.91  E-value: 2.41e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  633 SAQTSVTQAQREKAELSRKVEELQACVETARQEQHEAQAQVAELELQLRSEQQKATEKErvaQEKDQLQEQLQALKESLK 712
Cdd:COG4942     17 AQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALE---QELAALEAELAELEKEIA 93

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  713 VTKGSLEEEKRRAADALEEQQRciSELKAETRSLVEQHKRERKELEEeragrkgleARLQQLGEAHQAETEVLRRELAEA 792
Cdd:COG4942     94 ELRAELEAQKEELAELLRALYR--LGRQPPLALLLSPEDFLDAVRRL---------QYLKYLAPARREQAEELRADLAEL 162

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  793 MAAQHTAESECEQLVKEVAAWRERYEDSQQEEAQYgamfQEQLMTLKEECEKARQELQEAKekvagieshselqisRQQN 872
Cdd:COG4942    163 AALRAELEAERAELEALLAELEEERAALEALKAER----QKLLARLEKELAELAAELAELQ---------------QEAE 223

                          250       260
                   ....*....|....*....|...
gi 1370459521  873 ELAELHANLARALQQVQEKEVRA 895
Cdd:COG4942    224 ELEALIARLEAEAAAAAERTPAA 246
COG5022 COG5022
Myosin heavy chain [General function prediction only];
235-486 2.52e-04

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 46.61  E-value: 2.52e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  235 LELAENRKLLTEKDAQIAMMQQRIDRLALLNEKQ--------------AASPLEPKE-LEELRDKNESL--TMRLHETLK 297
Cdd:COG5022    803 LSLLGSRKEYRSYLACIIKLQKTIKREKKLRETEevefslkaevliqkFGRSLKAKKrFSLLKKETIYLqsAQRVELAER 882

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  298 QCQDLKTEksqmDRKINQLSEENGDLSFKLREFASHLQQLQDALNELTEEHSKATQEWL---------EKQAQLEKELSA 368
Cdd:COG5022    883 QLQELKID----VKSISSLKLVNLELESEIIELKKSLSSDLIENLEFKTELIARLKKLLnnidleegpSIEYVKLPELNK 958

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  369 ALQDKKCLEEKNEILQGKLSQLEEHLSQLqdNPPQEKgevlgdvlqLETLKQEAATLAANNTQLQARVEMLEtERGQQEA 448
Cdd:COG5022    959 LHEVESKLKETSEEYEDLLKKSTILVREG--NKANSE---------LKNFKKELAELSKQYGALQESTKQLK-ELPVEVA 1026

                          250       260       270
                   ....*....|....*....|....*....|....*...
gi 1370459521  449 KLLAERGHFEEEKQQLSSLiTDLQSSISNLSQAKEELE 486
Cdd:COG5022   1027 ELQSASKIISSESTELSIL-KPLQKLKGLLLLENNQLQ 1063
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1016-1233 2.97e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.53  E-value: 2.97e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1016 AQADLAleKAARAELEmRLQNALNEQRVEFATLQEALAHALTEKEGKDQELAKLRGLEAAQIKELEELRQTVKQLKEQLA 1095
Cdd:COG4942     17 AQADAA--AEAEAELE-QLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIA 93

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1096 KKEKEHASGSGAQSE---AAGRTEPTGPKLEALRAE-VSKLEQQCQKQQEQADSLERSLEAERASRAERDSALETLQGQL 1171
Cdd:COG4942     94 ELRAELEAQKEELAEllrALYRLGRQPPLALLLSPEdFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAER 173

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1370459521 1172 EEKAQELGHSQSALASAQRELAAFRTKVQDHSKAEDEWKAQVARGRQEAERKNSLISSLEEE 1233
Cdd:COG4942    174 AELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAE 235
mukB PRK04863
chromosome partition protein MukB;
300-498 2.99e-04

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 46.10  E-value: 2.99e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  300 QDLKTEKSQMDRKINQLSEENGDLSF---KLREFASHLQQLQDALNELTEEHskatqeWLEKQAQLEKELSAALQDKKCL 376
Cdd:PRK04863   840 RQLNRRRVELERALADHESQEQQQRSqleQAKEGLSALNRLLPRLNLLADET------LADRVEEIREQLDEAEEAKRFV 913

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  377 EEKneilQGKLSQLEEHLSQLQdNPPQEKGEVLGDVLQ----LETLKQEAATL----------------------AANNT 430
Cdd:PRK04863   914 QQH----GNALAQLEPIVSVLQ-SDPEQFEQLKQDYQQaqqtQRDAKQQAFALtevvqrrahfsyedaaemlaknSDLNE 988

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1370459521  431 QLQARVEMLETERGQQEAKLlaeRGHfEEEKQQLSSLITDLQSSISNLSQAKEELEQASQAHGARLTA 498
Cdd:PRK04863   989 KLRQRLEQAEQERTRAREQL---RQA-QAQLAQYNQVLASLKSSYDAKRQMLQELKQELQDLGVPADS 1052
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 560-769 3.12e-04

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 45.88  E-value: 3.12e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  560 LKQKEQQLKEVAEKQEATRQDHAQQLATAAEEREaslRERDAALKQLEALEKEKAAKLEilqQQLQVANEARDSAQTSVT 639
Cdd:pfam17380  355 QEERKRELERIRQEEIAMEISRMRELERLQMERQ---QKNERVRQELEAARKVKILEEE---RQRKIQQQKVEMEQIRAE 428

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  640 QAQREKAELSRKVEELQACVETARQEQHEAQAQVAELELQLRSEQQKATEKERVAQEKDQLQEQ-LQALKESLKVTKGSL 718
Cdd:pfam17380  429 QEEARQREVRRLEEERAREMERVRLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEEQrRKILEKELEERKQAM 508

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1370459521  719 EEEKR-----------RAADALEEQQRCISELKAETRSLVEQHKRERKELEEERAGRKGLEA 769
Cdd:pfam17380  509 IEEERkrkllekemeeRQKAIYEEERRREAEEERRKQQEMEERRRIQEQMRKATEERSRLEA 570
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 196-452 3.27e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.53  E-value: 3.27e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  196 FLSGSPASPMGDILQTPQFQMRRLKKQLADERSNRDELELELAENRKLLTEKDAQIAMMQQRIDRLAllnekqaasplep 275
Cdd:COG4942      9 LLLALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALE------------- 75

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  276 KELEELRDKNESLTMRLHETLKQCQDLKTEKSQMDRKINQLSEENGDLSFKLREFASHLQQLQDALNELTEEHSKATQEW 355
Cdd:COG4942     76 QELAALEAELAELEKEIAELRAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEEL 155

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  356 LEKQAQLEKELSAALQDKKCLEEKNEILQGKLSQLEEHLSQLQDNPPQEKGevlgdvlQLETLKQEAATLAANNTQLQAR 435
Cdd:COG4942    156 RADLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEK-------ELAELAAELAELQQEAEELEAL 228

                          250
                   ....*....|....*..
gi 1370459521  436 VEMLETERGQQEAKLLA 452
Cdd:COG4942    229 IARLEAEAAAAAERTPA 245
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
572-749 3.28e-04

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 45.78  E-value: 3.28e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  572 EKQEATRQDHAQQLATAAEEREASLRER-DAALKQLEALEKEKaaKLEILQQQLQVANEARDSAQTSVTQAQREKAELSR 650
Cdd:COG3206    163 EQNLELRREEARKALEFLEEQLPELRKElEEAEAALEEFRQKN--GLVDLSEEAKLLLQQLSELESQLAEARAELAEAEA 240

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  651 KVEELQACVETARQEQHEA---------QAQVAELELQLRSEQQKATEKERVAQekdQLQEQLQALKESLKVTKGSLEEE 721
Cdd:COG3206    241 RLAALRAQLGSGPDALPELlqspviqqlRAQLAELEAELAELSARYTPNHPDVI---ALRAQIAALRAQLQQEAQRILAS 317

                          170       180
                   ....*....|....*....|....*...
gi 1370459521  722 KRRAADALEEQQRCISELKAETRSLVEQ 749
Cdd:COG3206    318 LEAELEALQAREASLQAQLAQLEARLAE 345
PRK10246 PRK10246
exonuclease subunit SbcC; Provisional
 236-744 3.42e-04

exonuclease subunit SbcC; Provisional


Pssm-ID: 182330 [Multi-domain]  Cd Length: 1047  Bit Score: 45.95  E-value: 3.42e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  236 ELAENRKLLTEKDAQIAMMQQRIDRLALLNEKQAASPLEPKELEElrdknesltmrlhETLKQCQDLKTEKSQMDRKINQ 315
Cdd:PRK10246   364 ELAGWRAQFSQQTSDREQLRQWQQQLTHAEQKLNALPAITLTLTA-------------DEVAAALAQHAEQRPLRQRLVA 430

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  316 LSEENGDLSFKLREFASHLQQLQDALNELTEEHSKATQEWLEKQAQlekelsaaLQDKKCLEEKNEilqgKLSQLEEHLS 395
Cdd:PRK10246   431 LHGQIVPQQKRLAQLQVAIQNVTQEQTQRNAALNEMRQRYKEKTQQ--------LADVKTICEQEA----RIKDLEAQRA 498

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  396 QLQDNPP--------------QEKGEVLGDVLQLETLKQEAATLAANNTQLQARVEMLETERGQQE---AKLLAERGHFE 458
Cdd:PRK10246   499 QLQAGQPcplcgstshpaveaYQALEPGVNQSRLDALEKEVKKLGEEGAALRGQLDALTKQLQRDEseaQSLRQEEQALT 578

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  459 EEKQQLSS---LITDLQSSISNLSQAKEELEQA----SQAHgaRLTAQVASLTSELTTLNATIQQQDQ----ELAGLKQQ 527
Cdd:PRK10246   579 QQWQAVCAslnITLQPQDDIQPWLDAQEEHERQlrllSQRH--ELQGQIAAHNQQIIQYQQQIEQRQQqlltALAGYALT 656

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  528 AKEKQAQLAQTLQQQEQASQGLRHQVEQlsSSLKQKEQQLKEVAEKQEATRQDHAQQLATAAEE-REA-----SLRERDA 601
Cdd:PRK10246   657 LPQEDEEASWLATRQQEAQSWQQRQNEL--TALQNRIQQLTPLLETLPQSDDLPHSEETVALDNwRQVheqclSLHSQLQ 734

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  602 ALKQLEALEKEKAAKleiLQQQLQVANEARDSAQTSVTQAQREKAELSRKVEELQACVETARQEQHEAQAQVAElelQLR 681
Cdd:PRK10246   735 TLQQQDVLEAQRLQK---AQAQFDTALQASVFDDQQAFLAALLDEETLTQLEQLKQNLENQRQQAQTLVTQTAQ---ALA 808

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1370459521  682 SEQQKATEKERVAQEKDQLQEQLQALKESLK---VTKGSLEEEKRRAADALEEQQRCISELKAETR 744
Cdd:PRK10246   809 QHQQHRPDGLDLTVTVEQIQQELAQLAQQLRentTRQGEIRQQLKQDADNRQQQQALMQQIAQATQ 874
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 660-977 3.61e-04

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 45.88  E-value: 3.61e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  660 ETARQEQHEAQAQVAELELQlRSEQQKATEKERVAQEKDQLQEQLQALKESLKVTKGSLEEEKRRAADALEEQQRCISEL 739
Cdd:pfam17380  269 EFLNQLLHIVQHQKAVSERQ-QQEKFEKMEQERLRQEKEEKAREVERRRKLEEAEKARQAEMDRQAAIYAEQERMAMERE 347

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  740 KAETRSLVEQHKRERKELEEERAGRKGLEAR-LQQLGEAHQAETEVLRRELaEAMAAQHTAESECEQLVKEVAAWRERYE 818
Cdd:pfam17380  348 RELERIRQEERKRELERIRQEEIAMEISRMReLERLQMERQQKNERVRQEL-EAARKVKILEEERQRKIQQQKVEMEQIR 426

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  819 dSQQEEAQygamfQEQLMTLKEECEKARQELQEAKekvagIESHSELQISRQQNELAelhanlaRALQQVQEKEVRAQKL 898
Cdd:pfam17380  427 -AEQEEAR-----QREVRRLEEERAREMERVRLEE-----QERQQQVERLRQQEEER-------KRKKLELEKEKRDRKR 488

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  899 ADDL------STLQEKMAATSKEVARLETLVRKAGEQQETASRELVKEPARAGDRQPEWLEE-----QQGRQFCSTQAAL 967
Cdd:pfam17380  489 AEEQrrkileKELEERKQAMIEEERKRKLLEKEMEERQKAIYEEERRREAEEERRKQQEMEErrriqEQMRKATEERSRL 568

                          330
                   ....*....|
gi 1370459521  968 QAMEREAEQM 977
Cdd:pfam17380  569 EAMEREREMM 578
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 1764-2034 3.68e-04

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 45.93  E-value: 3.68e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1764 PDGTSVPGEPASPISQRlPPKVESLESLYFTPIPARSQA--PLESSLDSLGDVFLDSGRKTRSARRRTTQIINITMTKKL 1841
Cdd:PHA03307   192 EPPPSTPPAAASPRPPR-RSSPISASASSPAPAPGRSAAddAGASSSDSSSSESSGCGWGPENECPLPRPAPITLPTRIW 270

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1842 DVEEPDsaNSSFYSTRSAPASQASLRATSSTQSLARLGSPDYGNSALLSLPGYRP-----TTRSSARRSQAGVSSGAPPG 1916
Cdd:PHA03307   271 EASGWN--GPSSRPGPASSSSSPRERSPSPSPSSPGSGPAPSSPRASSSSSSSREsssssTSSSSESSRGAAVSPGPSPS 348

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1917 RNsfymGTCQDEPeqldDWNRIAELQQRnrvCPPHLKTCYPLESRPSlslgtitdeemktgdpqETLRRASMQ---PIQI 1993
Cdd:PHA03307   349 RS----PSPSRPP----PPADPSSPRKR---PRPSRAPSSPAASAGR-----------------PTRRRARAAvagRARR 400

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|.
gi 1370459521 1994 AEGTGITTRQQRKRVSLEPHQGPGTPESKkatscfPRPMTP 2034
Cdd:PHA03307   401 RDATGRFPAGRPRPSPLDAGAASGAFYAR------YPLLTP 435
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
815-1037 3.82e-04

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 45.78  E-value: 3.82e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  815 ERYEDSQQEEAQYGAMF-QEQLMTLKEECEKARQELQEAKEKVAGIESHSELQISRQQneLAELHANLARALQQVQEKEV 893
Cdd:COG3206    163 EQNLELRREEARKALEFlEEQLPELRKELEEAEAALEEFRQKNGLVDLSEEAKLLLQQ--LSELESQLAEARAELAEAEA 240

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  894 RAQKLADDLSTLQEKMAATSKevarlETLVRKAGEQQETASRELVKEPARAGDRQPE-------------WLEEQQGRQF 960
Cdd:COG3206    241 RLAALRAQLGSGPDALPELLQ-----SPVIQQLRAQLAELEAELAELSARYTPNHPDvialraqiaalraQLQQEAQRIL 315

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1370459521  961 CSTQAALQAMEREAEQMGNELERLRAALMEsqgqqqeeRGQQEREVARLTQERGRAQA--DLALEKAARAELEMRLQNA 1037
Cdd:COG3206    316 ASLEAELEALQAREASLQAQLAQLEARLAE--------LPELEAELRRLEREVEVARElyESLLQRLEEARLAEALTVG 386
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 894-1131 3.95e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.14  E-value: 3.95e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  894 RAQKLADDLSTLQEKMAATSKEVARLETLVRKAGEQQETASRELVkeparagdrqpewleeQQGRQFCSTQAALQAMERE 973
Cdd:COG4942     21 AAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIA----------------ALARRIRALEQELAALEAE 84

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  974 AEQMGNELERLRAALmESQGQQQEERGQQEREVARLTQERGRAQADLALEKAARAELEMRLQNALNEQRVEFATLQEALA 1053
Cdd:COG4942     85 LAELEKEIAELRAEL-EAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELA 163

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1370459521 1054 HALTEKEGKDQELAKLRGLEAAQIKELEELRQTVKQLKEQLAKKEKEHASGSGAQSEAAGRTEPTGPKLEALRAEVSK 1131
Cdd:COG4942    164 ALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAE 241
PRK11637 PRK11637
AmiB activator; Provisional
 565-827 4.27e-04

AmiB activator; Provisional


Pssm-ID: 236942 [Multi-domain]  Cd Length: 428  Bit Score: 45.07  E-value: 4.27e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  565 QQLK----EVAEKQEATRQdhaQQlataaeereaslRERDAALKQLEALEKEKAA---KLEILQQQLQVANEARDSAQTS 637
Cdd:PRK11637    47 DQLKsiqqDIAAKEKSVRQ---QQ------------QQRASLLAQLKKQEEAISQasrKLRETQNTLNQLNKQIDELNAS 111

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  638 VTQAQREKAELSRKveeLQACVETA-RQEQHEAqaqvaeLELQLRSEQQKatEKERVAQEKDQLQEQLQALKESLKVTKG 716
Cdd:PRK11637   112 IAKLEQQQAAQERL---LAAQLDAAfRQGEHTG------LQLILSGEESQ--RGERILAYFGYLNQARQETIAELKQTRE 180

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  717 SLEEEKRRAADALEEQQRCISELKAETRSLveqhkrerkelEEERAGRK----GLEARL----QQLGEAHQAETEvLRRE 788
Cdd:PRK11637   181 ELAAQKAELEEKQSQQKTLLYEQQAQQQKL-----------EQARNERKktltGLESSLqkdqQQLSELRANESR-LRDS 248

                          250       260       270
                   ....*....|....*....|....*....|....*....
gi 1370459521  789 LAEAMAAqhtAESECEQLVKEVAAWRERYEDSQQEEAQY 827
Cdd:PRK11637   249 IARAERE---AKARAEREAREAARVRDKQKQAKRKGSTY 284
PRK09039 PRK09039
peptidoglycan -binding protein;
496-692 4.48e-04

peptidoglycan -binding protein;


Pssm-ID: 181619 [Multi-domain]  Cd Length: 343  Bit Score: 44.96  E-value: 4.48e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  496 LTAQVASLTSELTTLNATIQQQDQELaGLKQQAKekqaqlaqtlqqqeqasQGLRHQVEQLSSSLKQKEQqlkEVAEKQE 575
Cdd:PRK09039    44 LSREISGKDSALDRLNSQIAELADLL-SLERQGN-----------------QDLQDSVANLRASLSAAEA---ERSRLQA 102

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  576 ATrqDHAQQLATAAEEREASLrerDAALKQLEALEKEKAAKLEILQQQLqvaneardsaqtsvtqaqrekAELSRKVEEL 655
Cdd:PRK09039   103 LL--AELAGAGAAAEGRAGEL---AQELDSEKQVSARALAQVELLNQQI---------------------AALRRQLAAL 156

                          170       180       190
                   ....*....|....*....|....*....|....*...
gi 1370459521  656 QACVETARQEQHEAQAQVAELELQLRSE-QQKATEKER 692
Cdd:PRK09039   157 EAALDASEKRDRESQAKIADLGRRLNVAlAQRVQELNR 194
PRK10929 PRK10929
putative mechanosensitive channel protein; Provisional
 1181-1588 4.89e-04

putative mechanosensitive channel protein; Provisional


Pssm-ID: 236798 [Multi-domain]  Cd Length: 1109  Bit Score: 45.43  E-value: 4.89e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1181 SQSALASAQRELAAFRTKVQDHSKAEDEWKAQVARGRQEA-----ERKNSLISSLEEEVSILNRQVLekegeSKELKRLV 1255
Cdd:PRK10929    14 SWGAYAATAPDEKQITQELEQAKAAKTPAQAEIVEALQSAlnwleERKGSLERAKQYQQVIDNFPKL-----SAELRQQL 88

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1256 MAESEKSQKLEERL-------RLLQAetasnsaraaerSSALREEVQSLREEAEKQRVASENLRQ--ELTSQAERA-EEL 1325
Cdd:PRK10929    89 NNERDEPRSVPPNMstdaleqEILQV------------SSQLLEKSRQAQQEQDRAREISDSLSQlpQQQTEARRQlNEI 156

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1326 GQELKAWQEKFFQKEQALST-LQLEHTSTQALVSELlpakhlcqqlqaeqaaaekrhreELEQ----SKQAAGGLRAELL 1400
Cdd:PRK10929   157 ERRLQTLGTPNTPLAQAQLTaLQAESAALKALVDEL-----------------------ELAQlsanNRQELARLRSELA 213

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1401 --RAQRELGELIPLRQKVAEQertaQQLRAEKASYAEQLsmlkkahglLAEENRGLGEraNLGRQF-LEVELDQAREKYV 1477
Cdd:PRK10929   214 kkRSQQLDAYLQALRNQLNSQ----RQREAERALESTEL---------LAEQSGDLPK--SIVAQFkINRELSQALNQQA 278

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1478 QELAAVRADAETRLAEVQ--REAQSTARE----LEVMTAKYEG--AKVKVLEERQRFQEerqkLTAQVEQLEVfqreQTK 1549
Cdd:PRK10929   279 QRMDLIASQQRQAASQTLqvRQALNTLREqsqwLGVSNALGEAlrAQVARLPEMPKPQQ----LDTEMAQLRV----QRL 350

                          410       420       430
                   ....*....|....*....|....*....|....*....
gi 1370459521 1550 QVEELSKKLADSDQASKVQQQKLKAVQAQGGESQQEAQR 1588
Cdd:PRK10929   351 RYEDLLNKQPQLRQIRQADGQPLTAEQNRILDAQLRTQR 389
PTZ00491 PTZ00491
major vault protein; Provisional
 620-739 4.89e-04

major vault protein; Provisional


Pssm-ID: 240439 [Multi-domain]  Cd Length: 850  Bit Score: 45.39  E-value: 4.89e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  620 LQQQLQVANEARDSAQTSVTQ------AQREKAELSRKVEELQACVETARQEQHEAQAQVAELEL--QLRSEQQKATEKE 691
Cdd:PTZ00491   649 LQKSVQLAIEITTKSQEAAARhqaellEQEARGRLERQKMHDKAKAEEQRTKLLELQAESAAVESsgQSRAEALAEAEAR 728

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*...
gi 1370459521  692 RVAQEKDQLQEQLQAlkESLKVTKGSLEEEKRRAADALEEQQRCISEL 739
Cdd:PTZ00491   729 LIEAEAEVEQAELRA--KALRIEAEAELEKLRKRQELELEYEQAQNEL 774
MAD pfam05557
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ...
 1215-1655 4.92e-04

Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.


Pssm-ID: 461677 [Multi-domain]  Cd Length: 660  Bit Score: 45.12  E-value: 4.92e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1215 RGRQEAERK-NSLISSLEEEVSILN------RQVLEKEGESKELKRLVMAESEKSQKLEERLRLLQAETASNSARAAERS 1287
Cdd:pfam05557   27 RARIELEKKaSALKRQLDRESDRNQelqkriRLLEKREAEAEEALREQAELNRLKKKYLEALNKKLNEKESQLADAREVI 106

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1288 SALREEVQSLREEAEKQRvasenlrQELTSQAERAEELGQELKAWQEKFFQKEQALSTLQlehTSTQALVSELLPAKHLc 1367
Cdd:pfam05557  107 SCLKNELSELRRQIQRAE-------LELQSTNSELEELQERLDLLKAKASEAEQLRQNLE---KQQSSLAEAEQRIKEL- 175

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1368 qqlqaeqaaaeKRHREELEQSKQAAGGLRAELLRaqrelgeliplrqkVAEQERTAQQLRAEKasyaEQLSMLKKAHGLL 1447
Cdd:pfam05557  176 -----------EFEIQSQEQDSEIVKNSKSELAR--------------IPELEKELERLREHN----KHLNENIENKLLL 226

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1448 AEENRGLgeRANLGRQfleveldqarEKYVQELAAVRADAETRLAEVQrEAQSTARELEVMTAKYEGAKVKVLEERQR-- 1525
Cdd:pfam05557  227 KEEVEDL--KRKLERE----------EKYREEAATLELEKEKLEQELQ-SWVKLAQDTGLNLRSPEDLSRRIEQLQQRei 293

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1526 -FQEERQKLTAQVEQLEVFQRE-------QTKQVEELSKKLADSD-QASKVQQQKLKAVQAQGG---------------- 1580
Cdd:pfam05557  294 vLKEENSSLTSSARQLEKARREleqelaqYLKKIEDLNKKLKRHKaLVRRLQRRVLLLTKERDGyrailesydkeltmsn 373

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1581 ----------ESQQEAQRLQAQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQELQEQLRSLE--QLQKENKEL 1648
Cdd:pfam05557  374 yspqllerieEAEDMTQKMQAHNEEMEAQLSVAEEELGGYKQQAQTLERELQALRQQESLADPSYSKEEvdSLRRKLETL 453


                   ....*..
gi 1370459521 1649 RAEAERL 1655
Cdd:pfam05557  454 ELERQRL 460
COG4995 COG4995
Uncharacterized conserved protein, contains CHAT domain [Function unknown];
510-947 5.09e-04

Uncharacterized conserved protein, contains CHAT domain [Function unknown];


Pssm-ID: 444019 [Multi-domain]  Cd Length: 711  Bit Score: 45.34  E-value: 5.09e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  510 LNATIQQQDQELAGLKQQAKEKQAQLAQTLQQQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEATRQDHAQQLATAA 589
Cdd:COG4995      2 LALALLALLAALLAALALALLALALLLLLAALAAAALLLLALLALLLALAAAAAAALAAAALALALLAAAALALLLLALA 81

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  590 EEREASLRERDAALKQLEALEKEKAAKLEILQQQLQVANEARDSAQTSVTQAQREKAELSRKVEELQACVETARQEQHEA 669
Cdd:COG4995     82 LAALALALLAAALALALAAAALAALALLAALLALAAAAALLALLAALALLALLAALAAALAAAAAAALAAALAAAAAAAA 161

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  670 QAQVAELELQLRSEQQKATEKERVAQEKDQLQEQLQALKESLKVTKGSLEEEKRRAADALEEQQRCISELKAETRSLVEQ 749
Cdd:COG4995    162 AAALLALALALAAAALALLALLLAALAAALAAAAAALALLLALLLLAALAAALAAALAALLLALLALAAALLALLLLALL 241

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  750 HKRERKELEEERAGRKGLEARLQQLGEAHQAETEVLRRELAEAMAAQHTAESECEQLVKEVAAWRERYEDSQQEEAQYGA 829
Cdd:COG4995    242 ALAAAAAALAAAAAALLALAAALLLLAALAALAAAAAAAALAALALAAALALAAAALALALLLAAAAAAALAALALLLLA 321

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  830 MFQEQLMTLKEECEKARQELQEAKEKVAGIESHSELQISRQQN-----ELAELHANLARALQQVQEKEVRAQKLADDLST 904
Cdd:COG4995    322 ALLLLLAALALLALLLLLAAAALLAAALAAALALAAALALALLaalllLLAALLALLLEALLLLLLALLAALLLLAAALL 401

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|...
gi 1370459521  905 LQEKMAATSKEVARLETLVRKAGEQQETASRELVKEPARAGDR 947
Cdd:COG4995    402 ALAAAQLLRLLLAALALLLALAAYAAARLALLALIEYIILPDR 444
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1412-1618 5.23e-04

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 45.01  E-value: 5.23e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1412 LRQKVAEQERTAQQLRAEKASYAEQL-------SMLKKAHGLLAEENRGLGERANLGRqfLEVELDQAREKYvQELAAVR 1484
Cdd:COG3206    166 LELRREEARKALEFLEEQLPELRKELeeaeaalEEFRQKNGLVDLSEEAKLLLQQLSE--LESQLAEARAEL-AEAEARL 242

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1485 ADAETRLAEVQREAQSTAR--ELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVEQLEVFQREQTKQVEELSKKLADSD 1562
Cdd:COG3206    243 AALRAQLGSGPDALPELLQspVIQQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAALRAQLQQEAQRILASLEAEL 322

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1370459521 1563 QASKVQQQKLKAVQAQGGESQQEAQRLQAQLNELQAQLSQKEQAAEHYKLQMEKAK 1618
Cdd:COG3206    323 EALQAREASLQAQLAQLEARLAELPELEAELRRLEREVEVARELYESLLQRLEEAR 378
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1315-1578 5.94e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 44.37  E-value: 5.94e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1315 LTSQAERAEELGQELKAWQEKFFQKEQALSTLQLEHTSTQALVSELlpakhlcqqlqaeqaaaekrhREELEQSKQAAGG 1394
Cdd:COG4942     15 AAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAAL---------------------ERRIAALARRIRA 73

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1395 LRAELLRAQRELGELIplrqkvAEQERTAQQLRAEKASYAEQLSMLKKAhgllaeenrGLGERANLGRQFLEVELDQARE 1474
Cdd:COG4942     74 LEQELAALEAELAELE------KEIAELRAELEAQKEELAELLRALYRL---------GRQPPLALLLSPEDFLDAVRRL 138

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1475 KYVQELAAVRADAETRLAEVQREAQSTARELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVEQLEVFQREQTKQVEEL 1554
Cdd:COG4942    139 QYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAEL 218

                          250       260
                   ....*....|....*....|....
gi 1370459521 1555 SKKLADSDQASKVQQQKLKAVQAQ 1578
Cdd:COG4942    219 QQEAEELEALIARLEAEAAAAAER 242
mukB PRK04863
chromosome partition protein MukB;
340-791 6.65e-04

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 44.95  E-value: 6.65e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  340 ALNELTEEHSKATQEWLEKQAQLEKELSAALQDKKCLEEKNE---ILQGKLSQLEEHLSQLQDNppqekgevlgdVLQLE 416
Cdd:PRK04863   280 ERRVHLEEALELRRELYTSRRQLAAEQYRLVEMARELAELNEaesDLEQDYQAASDHLNLVQTA-----------LRQQE 348

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  417 TLKQEAATLAANNTQLQARVEMLETERGQQEAKllaerghfEEEKQQLSSLITDLQSSISNLSQAKEELE-------QAS 489
Cdd:PRK04863   349 KIERYQADLEELEERLEEQNEVVEEADEQQEEN--------EARAEAAEEEVDELKSQLADYQQALDVQQtraiqyqQAV 420

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  490 QA-HGARLTAQVASLTSE-----LTTLNATIQQQDQELAGLKQQakekqaqlaqtlqqqeqasqglrhqveqLSSS---L 560
Cdd:PRK04863   421 QAlERAKQLCGLPDLTADnaedwLEEFQAKEQEATEELLSLEQK----------------------------LSVAqaaH 472

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  561 KQKEQQLKEVAEKQEATRQDHAQQLATAAEEREASLRERDAALKQLEAlekeKAAKLEILQQQLQVANEARDSAQTSVTQ 640
Cdd:PRK04863   473 SQFEQAYQLVRKIAGEVSRSEAWDVARELLRRLREQRHLAEQLQQLRM----RLSELEQRLRQQQRAERLLAEFCKRLGK 548

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  641 AQREKAELSRKVEELQACVETARQEQHEAQAQVAELELQLRSEQQKATEKERVAQEKDQLQEQLQALKEslkvtkgslee 720
Cdd:PRK04863   549 NLDDEDELEQLQEELEARLESLSESVSEARERRMALRQQLEQLQARIQRLAARAPAWLAAQDALARLRE----------- 617

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1370459521  721 ekrRAADALEEQQRCISELKAetrsLVEQHKRERKELEEERAGRKGLEARLQQLGEAHQAETEVLRReLAE 791
Cdd:PRK04863   618 ---QSGEEFEDSQDVTEYMQQ----LLERERELTVERDELAARKQALDEEIERLSQPGGSEDPRLNA-LAE 680
EmrA COG1566
Multidrug resistance efflux pump EmrA [Defense mechanisms];
1569-1697 7.19e-04

Multidrug resistance efflux pump EmrA [Defense mechanisms];


Pssm-ID: 441174 [Multi-domain]  Cd Length: 331  Bit Score: 44.27  E-value: 7.19e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1569 QQKLKAVQAQGGESQQEAQRLQAQLnELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQELQEQLRSLEQLQKENKEL 1648
Cdd:COG1566     82 QAALAQAEAQLAAAEAQLARLEAEL-GAEAEIAAAEAQLAAAQAQLDLAQRELERYQALYKKGAVSQQELDEARAALDAA 160

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*....
gi 1370459521 1649 RAEAERLGHELQQAGLKTKEAEQTcRHLTAQVRSLEAQVAHADQQLRDL 1697
Cdd:COG1566    161 QAQLEAAQAQLAQAQAGLREEEEL-AAAQAQVAQAEAALAQAELNLART 208
DUF1633 pfam07794
Protein of unknown function (DUF1633); This family contains sequences derived from a group of ...
 556-738 7.21e-04

Protein of unknown function (DUF1633); This family contains sequences derived from a group of hypothetical proteins expressed by Arabidopsis thaliana. These sequences are highly similar and the region concerned is about 100 residues long.


Pssm-ID: 116408 [Multi-domain]  Cd Length: 698  Bit Score: 44.88  E-value: 7.21e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  556 LSSSLKQKEQQLKEVAEKQEATRQDHAQQLATAAEEREASLRERDAALKQLEALEKEKAAKLEILQQQLQVANEARDSAQ 635
Cdd:pfam07794  446 LRASAKEGEEGERAIREEDPHLGADQDREVRFGAEGIVPGIERLKIELSTSKDLEKGYAEKIGFMEMEFGGLEADKQMAR 525

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  636 TSVTQAQREKAELSRKVEELQACVETARQEQHEAQAQVAELELQLRS--EQQKATEKERVAQEkDQLQEQLQALKESLKV 713
Cdd:pfam07794  526 NQIHRLEEKKDELSKKVLDLTSIAQGAKKAVHDAKVELAAAYLKLLAgiKDKWVAKKEFTVLE-GQAAEVESNLALIDQI 604

                          170       180
                   ....*....|....*....|....*...
gi 1370459521  714 TKGSLE---EEKRRAADALEEQQRCISE 738
Cdd:pfam07794  605 TKAAIDltlEKPRFQAEIDDLEARCKLK 632
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
700-1201 7.25e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 44.76  E-value: 7.25e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  700 LQEQLQALKESLKVTKGSLEEEKRRAADALEEQQRCISELKAETRSLVEQHKRERKELEEERAGRKGLEARLQQLGEAHQ 779
Cdd:COG4717     47 LLERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQ 126

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  780 AETEVLRRELAEAMAAQhtAESECEQLVKEVAAWRERYEDSQQEEAQYGAMFQEQLMTLKEECEKARQELQEAKEKVAGI 859
Cdd:COG4717    127 LLPLYQELEALEAELAE--LPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEEL 204

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  860 EShselQISRQQNELAELHANLARALQQVQEKEVRAQKLADDLSTLQEKMAAtskeVARLETLVRKAGEQQETASRELVK 939
Cdd:COG4717    205 QQ----RLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLLL----LIAAALLALLGLGGSLLSLILTIA 276

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  940 EPARAGDRQPEWLEEQQGRQFCSTQAALQAMEREAEQMGNELERLRAALMESQGQQQEERGQQEREVARLtqergrAQAD 1019
Cdd:COG4717    277 GVLFLVLGLLALLFLLLAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRI------EELQ 350

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1020 LALEKAARAELEMRLQNALNEQRVEFATLQEALAHALTEKegkdqelaklrgleAAQIKELEELRQTVKQLKEQLAKKEK 1099
Cdd:COG4717    351 ELLREAEELEEELQLEELEQEIAALLAEAGVEDEEELRAA--------------LEQAEEYQELKEELEELEEQLEELLG 416

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1100 EHASGSGAQSEAAGRTEptgpkLEALRAEVSKLEQQCQKQQEQADSLERSLeaERASRAERDSALETLQGQLEEKAQELG 1179
Cdd:COG4717    417 ELEELLEALDEEELEEE-----LEELEEELEELEEELEELREELAELEAEL--EQLEEDGELAELLQELEELKAELRELA 489

                          490       500
                   ....*....|....*....|..
gi 1370459521 1180 HSQSALASAQRELAAFRTKVQD 1201
Cdd:COG4717    490 EEWAALKLALELLEEAREEYRE 511
COG3899 COG3899
Predicted ATPase [General function prediction only];
1007-1530 7.71e-04

Predicted ATPase [General function prediction only];


Pssm-ID: 443106 [Multi-domain]  Cd Length: 1244  Bit Score: 44.85  E-value: 7.71e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1007 ARLTQERGRAQADLALEKAARAELEMRLQNALNEQRVEFATLQEALAHALTEKEGKDQELAKLRGLEAAQIKELEELRQT 1086
Cdd:COG3899    732 LELLPPDPEEEYRLALLLELAEALYLAGRFEEAEALLERALAARALAALAALRHGNPPASARAYANLGLLLLGDYEEAYE 811

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1087 VKQLKEQLAKKEKEHASGSGAQSEAAGRTEPTGPKLEALRAEvskLEQQCQKQQEQADSLERSLEAERASRAERDSALET 1166
Cdd:COG3899    812 FGELALALAERLGDRRLEARALFNLGFILHWLGPLREALELL---REALEAGLETGDAALALLALAAAAAAAAAAAALAA 888

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1167 LQGQLEEKAQELGHSQSALASAQRELAAFRTKVQDHSKAEDEWKAQVARGRQEAERKNSLISSLEEEVSILNRQVLEKEG 1246
Cdd:COG3899    889 AAAAAARLLAAAAAALAAAAAAAALAAAELARLAAAAAAAAALALAAAAAAAAAAALAAAAAAAALAAALALAAAAAAAA 968

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1247 ESKELKRLVMAESEKSQKLEERLRLLQAETASNSARAAERSSALREEVQSLREEAEKQRVASENLRQELTSQAERAEELG 1326
Cdd:COG3899    969 AAALAAAAAAAAAAAAAAAAAALEAAAAALLALLAAAAAAAAAAAALAAALLAAALAALAAAAAAAALLAAAAALALLAA 1048

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1327 QELkawqekffqkEQALSTLQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKRHREELEQSKQAAGGLRAELLRAQREL 1406
Cdd:COG3899   1049 LAA----------AAAAAAAAAALAAAAALLAAAAAAAAAAAAAAAAAALAAALAAAALAAAAAAALALAAALAALALAA 1118

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1407 GELIPLRQKVAEQERTAQQLRAEKASYAEQLSMLKKAHGLLAEENRGLGERANLGRQFLEVELDQAREKYVQELAAVRAD 1486
Cdd:COG3899   1119 ALAALALAAAARAAAALLLLAAALALALAALLLLAALLLALALLLLALAALALAAALAALAAALLAAAAAAAAAAALLAA 1198

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|....
gi 1370459521 1487 AETRLAEVQREAQSTARELEVMTAKYEGAKVKVLEERQRFQEER 1530
Cdd:COG3899   1199 LLALAARLAALLALALLALEAAALLLLLLLAALALAAALLALRL 1242
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
326-607 7.97e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 44.91  E-value: 7.97e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  326 KLREFASHLQQLQDALNELTEEHSKATQEwlEKQAQLEKELSAALQDKKCLEEKNEILQGKLSQLEEHLSQLQDNPPQek 405
Cdd:COG4913    611 KLAALEAELAELEEELAEAEERLEALEAE--LDALQERREALQRLAEYSWDEIDVASAEREIAELEAELERLDASSDD-- 686

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  406 gevlgdvlqLETLKQEAATLAANNTQLQARVEMLETERGQQEAKLlaerghfEEEKQQLSSLITDLQSSISNLSQAKEEL 485
Cdd:COG4913    687 ---------LAALEEQLEELEAELEELEEELDELKGEIGRLEKEL-------EQAEEELDELQDRLEAAEDLARLELRAL 750

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  486 --EQASQAHGARLTAQV-ASLTSELTTLNATIQQQDQELAGLKQQAKEKQAQLAQTLQQQEQASQGLRHQVEQLSSS-LK 561
Cdd:COG4913    751 leERFAAALGDAVERELrENLEERIDALRARLNRAEEELERAMRAFNREWPAETADLDADLESLPEYLALLDRLEEDgLP 830

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*..
gi 1370459521  562 QKEQQLKEVAEKQEATRQDH-AQQLATAAEEREASLRERDAALKQLE 607
Cdd:COG4913    831 EYEERFKELLNENSIEFVADlLSKLRRAIREIKERIDPLNDSLKRIP 877
mukB PRK04863
chromosome partition protein MukB;
326-700 8.07e-04

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 44.95  E-value: 8.07e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  326 KLREFASHLQQLQDALNELTEEHSKAT------QEWLEKQAQLEKELSAALQDKKCLEEKNEIL---QGKLSQLEEHLSQ 396
Cdd:PRK04863   308 RLVEMARELAELNEAESDLEQDYQAASdhlnlvQTALRQQEKIERYQADLEELEERLEEQNEVVeeaDEQQEENEARAEA 387

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  397 LQDNPPQEKGEvLGDVLQLETLKQEAATlaanntQLQARVEMLETERGQQEAKLLAERG------HFEEEKQQLSSLITD 470
Cdd:PRK04863   388 AEEEVDELKSQ-LADYQQALDVQQTRAI------QYQQAVQALERAKQLCGLPDLTADNaedwleEFQAKEQEATEELLS 460

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  471 LQSSISNLSQAKEELEQASQ---AHGARLTAQVASLTS-ELTTLNATIQQQDQELAGLKQQAKEkqaqlAQTLQQQEQAS 546
Cdd:PRK04863   461 LEQKLSVAQAAHSQFEQAYQlvrKIAGEVSRSEAWDVArELLRRLREQRHLAEQLQQLRMRLSE-----LEQRLRQQQRA 535

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  547 QGLRHQVEQLSSSLKQKEQQLKEVAEKQEATRQDHAQQLATAAEEREASLRErdaaLKQLEAlekeKAAKLEILQQQLQV 626
Cdd:PRK04863   536 ERLLAEFCKRLGKNLDDEDELEQLQEELEARLESLSESVSEARERRMALRQQ----LEQLQA----RIQRLAARAPAWLA 607

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1370459521  627 ANEARDSAQTSVTQAQREKAELSRKVEELQACVETARQEQHEAQAQVAELELQLRSEQQKAT-EKERVAQEKDQL 700
Cdd:PRK04863   608 AQDALARLREQSGEEFEDSQDVTEYMQQLLERERELTVERDELAARKQALDEEIERLSQPGGsEDPRLNALAERF 682
YqiK COG2268
Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain [Function unknown];
563-712 8.69e-04

Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain [Function unknown];


Pssm-ID: 441869 [Multi-domain]  Cd Length: 439  Bit Score: 44.09  E-value: 8.69e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  563 KEQQLKEVAEKQEATRQDHAQQLATAAEEREAslRERDAALKQLEALEKEKAAKLEILQQQLQVANEARDSAQtsvtQAQ 642
Cdd:COG2268    198 IRDARIAEAEAERETEIAIAQANREAEEAELE--QEREIETARIAEAEAELAKKKAEERREAETARAEAEAAY----EIA 271

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  643 REKAELsrkveELQACVETARQEQheaQAQVAELELQLRSEQQKATEKERVAQEKDQLQEQLQALKESLK 712
Cdd:COG2268    272 EANAER-----EVQRQLEIAERER---EIELQEKEAEREEAELEADVRKPAEAEKQAAEAEAEAEAEAIR 333
Crescentin pfam19220
Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament ...
 1078-1347 1.27e-03

Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament proteins, named crescentin, whose cytoskeletal function is required for the vibrioid and helical shapes of Caulobacter crescentus. Without crescentin, the cells adopt a straight-rod morphology. Crescentin has characteriztic features of IF proteins including the ability to assemble into filaments in vitro without energy or cofactor requirements. In vivo, crescentin forms a helical structure that colocalizes with the inner cell curvatures beneath the cytoplasmic membrane.


Pssm-ID: 437057 [Multi-domain]  Cd Length: 401  Bit Score: 43.52  E-value: 1.27e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1078 KELEELRQTVKQLKEQLAKKEKEHASGSGAQSEAAGRTEptgpKLEALRAEVSKLEQQCQKQQEQADSLERSLEAERASR 1157
Cdd:pfam19220   38 AILRELPQAKSRLLELEALLAQERAAYGKLRRELAGLTR----RLSAAEGELEELVARLAKLEAALREAEAAKEELRIEL 113

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1158 AERDSALETLQGQLEEKAQELGHSQSALASAQRELAAFRTKVQDHSKAEDEWKAQVARGRQEAERKNSLISSLEEEVSIL 1237
Cdd:pfam19220  114 RDKTAQAEALERQLAAETEQNRALEEENKALREEAQAAEKALQRAEGELATARERLALLEQENRRLQALSEEQAAELAEL 193

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1238 NRQVLEKEGESK-ELKRLVMAESEKSQKLEERLRLLQAETASNSARAAERSSA-----------------LREEVQSLRE 1299
Cdd:pfam19220  194 TRRLAELETQLDaTRARLRALEGQLAAEQAERERAEAQLEEAVEAHRAERASLrmklealtaraaateqlLAEARNQLRD 273

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1370459521 1300 EAEKQRVASENLRQ---ELTSQAERAEELGQELKAWQEKFFQKEQALSTLQ 1347
Cdd:pfam19220  274 RDEAIRAAERRLKEasiERDTLERRLAGLEADLERRTQQFQEMQRARAELE 324
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1481-1721 1.29e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.60  E-value: 1.29e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1481 AAVRADAETRLAEVQREAQSTARELEvmtakyegakvKVLEERQRFQEERQKLTAQVEQLEVFQREQTKQVEELSKKLAD 1560
Cdd:COG4942     19 ADAAAEAEAELEQLQQEIAELEKELA-----------ALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAE 87

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1561 SDQASKVQQQKLKAVQAQGGESQQEAQRLQAQlNELQAQLSQKEQAAEHYKLQMEKAKTHYDAK-----KQQNQELQEQL 1635
Cdd:COG4942     88 LEKEIAELRAELEAQKEELAELLRALYRLGRQ-PPLALLLSPEDFLDAVRRLQYLKYLAPARREqaeelRADLAELAALR 166

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1636 RSLEQLQKENKELRAEAERLGHELQQAglkTKEAEQTCRHLTAQVRSLEAQVAHADQQLRDLGKFQVATDALKSREPQAK 1715
Cdd:COG4942    167 AELEAERAELEALLAELEEERAALEAL---KAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERT 243


                   ....*.
gi 1370459521 1716 PQLDLS 1721
Cdd:COG4942    244 PAAGFA 249
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1456-1662 1.44e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 43.85  E-value: 1.44e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1456 ERANLGRQFLEVELDQAREKYVQELAAVRA-DAETRLAEVQREAQSTARELEVMTAKYEGAKVKVLEERQRFQEERQKLT 1534
Cdd:COG3206    171 EEARKALEFLEEQLPELRKELEEAEAALEEfRQKNGLVDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLG 250

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1535 AQVEQLEVFQreQTKQVEELSKKLADsdqaskvQQQKLKAVQAQGGESQQEAQRLQAQLNELQAQLSQKEQAAehyklqM 1614
Cdd:COG3206    251 SGPDALPELL--QSPVIQQLRAQLAE-------LEAELAELSARYTPNHPDVIALRAQIAALRAQLQQEAQRI------L 315

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*...
gi 1370459521 1615 EKAKTHYDAKKQQNQELQEQLRSLEQLQKENKELRAEAERLGHELQQA 1662
Cdd:COG3206    316 ASLEAELEALQAREASLQAQLAQLEARLAELPELEAELRRLEREVEVA 363
Borrelia_P83 pfam05262
Borrelia P83/100 protein; This family consists of several Borrelia P83/P100 antigen proteins.
 575-748 1.49e-03

Borrelia P83/100 protein; This family consists of several Borrelia P83/P100 antigen proteins.


Pssm-ID: 114011 [Multi-domain]  Cd Length: 489  Bit Score: 43.45  E-value: 1.49e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  575 EATRQDHAQQLATAAEEREASLRERDAALKQLEALEKE---KAAKLEILQQQLQVANEARDSAQTSVTQAQREKAELSRK 651
Cdd:pfam05262  184 EALREDNEKGVNFRRDMTDLKERESQEDAKRAQQLKEEldkKQIDADKAQQKADFAQDNADKQRDEVRQKQQEAKNLPKP 263

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  652 veelqACVETARQEQHEAQAQVAELElqlRSEQQKATEKERVAQEKDQLQEQL-QALKESLKVTKGSLEEEKRRAADALE 730
Cdd:pfam05262  264 -----ADTSSPKEDKQVAENQKREIE---KAQIEIKKNDEEALKAKDHKAFDLkQESKASEKEAEDKELEAQKKREPVAE 335

                          170
                   ....*....|....*...
gi 1370459521  731 EQQRCISELKAETRSLVE 748
Cdd:pfam05262  336 DLQKTKPQVEAQPTSLNE 353
ClpA COG0542
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ...
 304-408 1.64e-03

ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440308 [Multi-domain]  Cd Length: 836  Bit Score: 43.53  E-value: 1.64e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  304 TEKSQMDRKINQLSEENGDLSfKLREFAS--HLQQLQDALNELTEEHSKATQEWLEkqaqlEKELSAALQD-KKCLEEKN 380
Cdd:COG0542    411 EELDELERRLEQLEIEKEALK-KEQDEASfeRLAELRDELAELEEELEALKARWEA-----EKELIEEIQElKEELEQRY 484

                           90       100
                   ....*....|....*....|....*...
gi 1370459521  381 EILQGKLSQLEEHLSQLQDNPPQEKGEV 408
Cdd:COG0542    485 GKIPELEKELAELEEELAELAPLLREEV 512
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
914-1335 1.86e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 43.22  E-value: 1.86e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  914 KEVARLETLVRKAGEQQETASRELVKEPARAGDRQPEWLEEQQGRQfcSTQAALQAMEREAEQMGNELERLRAALmeSQG 993
Cdd:COG4717     53 KEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELE--ELEEELEELEAELEELREELEKLEKLL--QLL 128

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  994 QQQEERGQQEREVARLTQERGRAQADLALEKAARAELEMRLQNALNEQRVEFATLQEALAHALTEKEGKDQELAKLRGLE 1073
Cdd:COG4717    129 PLYQELEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRL 208

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1074 AAQIKELEELRQTVKQLKEQLAKKEKEHASGSGAQSEAAGR--------------TEPTGPKLEALRAEVSKLEQQCQKQ 1139
Cdd:COG4717    209 AELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARlllliaaallallgLGGSLLSLILTIAGVLFLVLGLLAL 288

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1140 QEQADSLERSLEAERASRAERDSALETLQGQ-LEEKAQELGHSQSALASAQRELAAFRTKVQDHSKAEDEWKAQVARGRQ 1218
Cdd:COG4717    289 LFLLLAREKASLGKEAEELQALPALEELEEEeLEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEEL 368

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1219 EAERKNSLISSLEEEVSILNRQVLEKEGESKELKRLVMAESEKSQKLEERLRLLQAETAsnsARAAERSSALREEVQSLR 1298
Cdd:COG4717    369 EQEIAALLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDE---EELEEELEELEEELEELE 445

                          410       420       430
                   ....*....|....*....|....*....|....*..
gi 1370459521 1299 EEAEKQRVASENLRQELtSQAERAEELGQELKAWQEK 1335
Cdd:COG4717    446 EELEELREELAELEAEL-EQLEEDGELAELLQELEEL 481
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 593-796 1.88e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 42.89  E-value: 1.88e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  593 EASLRERDAALKQLEALEKEKAAKLEILQQQLQVANEARDSAQTSVTQAQREKAELSRKVEELQACVETARQE------- 665
Cdd:COG3883     15 DPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREElgerara 94

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  666 QHEAQAQVAELELQLRSEQQKATEKERVAQekDQLQEQLQALKESLKVTKGSLEEEKRRAADALEEQQRCISELKAETRS 745
Cdd:COG3883     95 LYRSGGSVSYLDVLLGSESFSDFLDRLSAL--SKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAE 172

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1370459521  746 LVEQHKRERKELEEERAGRKGLEARLQQLGEAHQAETEVLRRELAEAMAAQ 796
Cdd:COG3883    173 LEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAA 223
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1525-1719 1.89e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 43.37  E-value: 1.89e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1525 RFQEERQKLTAQVEQLEVFqREQTKQVEELSKKLADSDQ-----ASKVQQQKLKAVQAQGGESQQEAQRLQAQLNELQAQ 1599
Cdd:COG4913    239 RAHEALEDAREQIELLEPI-RELAERYAAARERLAELEYlraalRLWFAQRRLELLEAELEELRAELARLEAELERLEAR 317

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1600 LSQKEQAAEHYKLQMEKAKThydakkqqnQELQEQLRSLEQLQKENKELRAEAERLGHELQQAGLKTKEAEQTcrhLTAQ 1679
Cdd:COG4913    318 LDALREELDELEAQIRGNGG---------DRLEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEE---FAAL 385

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|
gi 1370459521 1680 VRSLEAQVAHADQQLRDLgkfQVATDALKSREPQAKPQLD 1719
Cdd:COG4913    386 RAEAAALLEALEEELEAL---EEALAEAEAALRDLRRELR 422
PRK10929 PRK10929
putative mechanosensitive channel protein; Provisional
 471-734 1.90e-03

putative mechanosensitive channel protein; Provisional


Pssm-ID: 236798 [Multi-domain]  Cd Length: 1109  Bit Score: 43.50  E-value: 1.90e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  471 LQSSISNLSQAKEELEQASQAHGARLTAQVASLTSELTTLNAT------IQQQDQEL-------AGLKQQAKEKqaQLAQ 537
Cdd:PRK10929    18 YAATAPDEKQITQELEQAKAAKTPAQAEIVEALQSALNWLEERkgslerAKQYQQVIdnfpklsAELRQQLNNE--RDEP 95

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  538 TLQQQEQASQGLRHQVEQLSSSLKQKEQQLkevaeKQEatrQDHAQQLATaaeereaslrerdaALKQLEALEKEKAAKL 617
Cdd:PRK10929    96 RSVPPNMSTDALEQEILQVSSQLLEKSRQA-----QQE---QDRAREISD--------------SLSQLPQQQTEARRQL 153

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  618 EILQQQLQVANEARDS-AQTSVTQAQREKAELSRKVEELQACVETA--RQE------------QHEAQAQVAELELQLRS 682
Cdd:PRK10929   154 NEIERRLQTLGTPNTPlAQAQLTALQAESAALKALVDELELAQLSAnnRQElarlrselakkrSQQLDAYLQALRNQLNS 233

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1370459521  683 EQQKATEK--ERVAQEKDQLQEQLQALKESLKVTK---GSLEEEKRRaADALEEQQR 734
Cdd:PRK10929   234 QRQREAERalESTELLAEQSGDLPKSIVAQFKINRelsQALNQQAQR-MDLIASQQR 289
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 552-745 1.95e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 42.89  E-value: 1.95e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  552 QVEQLSSSLKQKEQQLKEVAEKQEATRQD---HAQQLATAAEEREASLRERDAALKQLEALEKEKAAKLEILQQQLQVAN 628
Cdd:COG3883     17 QIQAKQKELSELQAELEAAQAELDALQAEleeLNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARALY 96

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  629 EARDSA--------QTSVTQAQREKAELSRKVEELQACVETARQEQHEAQAQVAELELQLRSEQQKATEKERVAQEKDQL 700
Cdd:COG3883     97 RSGGSVsyldvllgSESFSDFLDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAELEAQ 176

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*
gi 1370459521  701 QEQLQALKESLKVTKGSLEEEKRRAADALEEQQRCISELKAETRS 745
Cdd:COG3883    177 QAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAA 221
CALCOCO1 pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
 259-625 2.03e-03

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 42.96  E-value: 2.03e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  259 DRLALLNEKQAASPLEPKELEELRDKNESLTMRLHETLKQCQDLKTEKSQMDRKINQLSEENGDLSFKLREFASHLQQLQ 338
Cdd:pfam07888   42 ERAELLQAQEAANRQREKEKERYKRDREQWERQRRELESRVAELKEELRQSREKHEELEEKYKELSASSEELSEEKDALL 121

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  339 DA-------LNELTEEHSKATQEWLEKQAQLEK---ELSAALQDKKCLEEKNEILQGKLSQLEEHLSQLQDNPPQEKGEV 408
Cdd:pfam07888  122 AQraahearIRELEEDIKTLTQRVLERETELERmkeRAKKAGAQRKEEEAERKQLQAKLQQTEEELRSLSKEFQELRNSL 201

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  409 LGDVLQLETLKQEAATLAANNTQLQARVemLETERGQQEAKLLAERGHFEEEKQQLssLITDLQSSISNLSQAKEELEQA 488
Cdd:pfam07888  202 AQRDTQVLQLQDTITTLTQKLTTAHRKE--AENEALLEELRSLQERLNASERKVEG--LGEELSSMAAQRDRTQAELHQA 277

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  489 sQAHGARLTAQVASLTSELTTLNATIQQQDQELaglkQQAKEKQaqlaqtlqqqeqasqglRHQVEQLSSSLKQKEQQLK 568
Cdd:pfam07888  278 -RLQAAQLTLQLADASLALREGRARWAQERETL----QQSAEAD-----------------KDRIEKLSAELQRLEERLQ 335

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1370459521  569 EVAEKQEATRQDHAQQLATAAEEREASLRERDAALKQLEALEKEKAAKLEILQQQLQ 625
Cdd:pfam07888  336 EERMEREKLEVELGREKDCNRVQLSESRRELQELKASLRVAQKEKEQLQAEKQELLE 392
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
773-1335 2.21e-03

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 43.13  E-value: 2.21e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  773 QLGEAHQAETEVLRR--ELAEAMAAQHTAESECEQLVKEVAAWRERYEDSQQEEA---QYGAMFQEQLMTLKEECEKARQ 847
Cdd:PRK03918   194 LIKEKEKELEEVLREinEISSELPELREELEKLEKEVKELEELKEEIEELEKELEsleGSKRKLEEKIRELEERIEELKK 273

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  848 ELQEAKEKVAGIEShselqISRQQNELAELHANLARALQQVQEKEVRAQKLADDLSTLQEKMAATSKEVARLETLVRKAG 927
Cdd:PRK03918   274 EIEELEEKVKELKE-----LKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLK 348

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  928 EQQETASRelVKEPARAGDRQPEWLEEQQG---RQFCSTQAALQAMEREAEQMGNELERLRAALMESQGQQQEERGQQER 1004
Cdd:PRK03918   349 ELEKRLEE--LEERHELYEEAKAKKEELERlkkRLTGLTPEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKK 426

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1005 EVARLTQERGRAQA-DLALEKAARAELEMRLQNALNEQRVEFATLQEALAHALTEKEGKDQELAKLRgleaaQIKELEEL 1083
Cdd:PRK03918   427 AIEELKKAKGKCPVcGRELTEEHRKELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKES-----ELIKLKEL 501

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1084 RQTVKQLKEQLAKKEKEHASgsgaqsEAAGRTEPTGPKLEALRAEVSKLEQQCQKQQEqadsLERSLEAERASRAERDSA 1163
Cdd:PRK03918   502 AEQLKELEEKLKKYNLEELE------KKAEEYEKLKEKLIKLKGEIKSLKKELEKLEE----LKKKLAELEKKLDELEEE 571

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1164 LETLQGQLEEKAQElghSQSALASAQRELAAFRTKVQDHSKAEdewkaqvargrQEAERKNSLISSLEEEVSILNRQVLE 1243
Cdd:PRK03918   572 LAELLKELEELGFE---SVEELEERLKELEPFYNEYLELKDAE-----------KELEREEKELKKLEEELDKAFEELAE 637

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1244 KEGESKELKRlvmaeseksqKLEERLRLLQAETASNsaraaerssaLREEVQSLREEAEKQRVASENLRQELTSQAERAE 1323
Cdd:PRK03918   638 TEKRLEELRK----------ELEELEKKYSEEEYEE----------LREEYLELSRELAGLRAELEELEKRREEIKKTLE 697

                          570
                   ....*....|..
gi 1370459521 1324 ELGQELKAWQEK 1335
Cdd:PRK03918   698 KLKEELEEREKA 709
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
594-910 2.36e-03

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 42.58  E-value: 2.36e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  594 ASLRERDAALKQLEALEKEkaakLEILQQQLQVANEARDSAQTSVTQAQREKAELSRKVEELQACVETARQEQHEAQAQV 673
Cdd:COG4372     28 ALSEQLRKALFELDKLQEE----LEQLREELEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEEL 103

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  674 AELELQLRSEQQKATEKERVAQEKDQLQEQLQALKESLKVTKGSLEEEKRRAADALEEQQRCISELKAETRSLVEQHKRE 753
Cdd:COG4372    104 ESLQEEAEELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQELQALSEAEAEQ 183

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  754 RKELEEERAGRKGLEARLQQLGEAHQAETEVLRRELAEAMAAQHTAESECEQLVKEVAAWRERYEDSQQEEAQYGAMFQE 833
Cdd:COG4372    184 ALDELLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKEELLEEVILKEIEEL 263

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1370459521  834 QLMTLKEECEKARQELQEAKEKVAGIESHSELQISRQQNELAELHANLARALQQVQEKEVRAQKLADDLSTLQEKMA 910
Cdd:COG4372    264 ELAILVEKDTEEEELEIAALELEALEEAALELKLLALLLNLAALSLIGALEDALLAALLELAKKLELALAILLAELA 340
Surf_Exclu_PgrA TIGR04320
SEC10/PgrA surface exclusion domain; This model describes a conserved domain found in surface ...
 603-712 2.45e-03

SEC10/PgrA surface exclusion domain; This model describes a conserved domain found in surface proteins of a number of Firmutes. Many members have LPXTG C-terminal anchoring motifs and a substantial number have the KxYKxGKxW putative sorting signal at the N-terminus. The tetracycline resistance plasmid pCF10 in Enterococcus faecalis promotes conjugal plasmid transfer in response to sex pheromones, but PgrA/Sec10 encoded by that plasmid, a member of this family, specifically inhibits the ability of cells to receive homologous plasmids. The phenomenon is called surface exclusion.


Pssm-ID: 275124 [Multi-domain]  Cd Length: 356  Bit Score: 42.41  E-value: 2.45e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  603 LKQLEALEKEKAAKLEILQQQLQVANEARDSAQTSVTQAQREKAELSRKVEELQAcvetarQEQHEAQAQVAELELQLrs 682
Cdd:TIGR04320  256 LAALQAKLATAQADLAAAQTALNTAQAALTSAQTAYAAAQAALATAQKELANAQA------QALQTAQNNLATAQAAL-- 327

                           90       100       110
                   ....*....|....*....|....*....|.
gi 1370459521  683 eqQKATEKERVAQEK-DQLQEQLQALKESLK 712
Cdd:TIGR04320  328 --ANAEARLAKAKEAlANLNADLAKKQAALD 356
CALCOCO1 pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
 337-686 2.69e-03

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 42.57  E-value: 2.69e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  337 LQDALNELTEEHSKATQEWLEKQAQLEKELSAALQDKKCLEEKNEILQGKLSQLEEHLSQLQDNPPQEKGEVLGDVLQLE 416
Cdd:pfam07888   32 LQNRLEECLQERAELLQAQEAANRQREKEKERYKRDREQWERQRRELESRVAELKEELRQSREKHEELEEKYKELSASSE 111

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  417 TLKQEAATLAANNTQLQARVEMLE------TERG-----------QQEAKLLAERGHFEEEKQQLSSlitDLQSSISNLS 479
Cdd:pfam07888  112 ELSEEKDALLAQRAAHEARIRELEediktlTQRVleretelermkERAKKAGAQRKEEEAERKQLQA---KLQQTEEELR 188

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  480 QAKEELEQASQAHGARLTaQVASLTSELTTLNATIQQQDQELAGLkQQAKEKQAQLAQTLQQQEQASQGLRhqvEQLSSS 559
Cdd:pfam07888  189 SLSKEFQELRNSLAQRDT-QVLQLQDTITTLTQKLTTAHRKEAEN-EALLEELRSLQERLNASERKVEGLG---EELSSM 263

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  560 LKQKEQQLKEV--AEKQEATRQDHAQQLATAAEEREASLRERDAALKQLEALEKEKAAKLEILQQQLQVA-NEARDSAQT 636
Cdd:pfam07888  264 AAQRDRTQAELhqARLQAAQLTLQLADASLALREGRARWAQERETLQQSAEADKDRIEKLSAELQRLEERlQEERMEREK 343

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1370459521  637 SVTQAQREK-------AELSRKVEELQACVETARQEQHEAQAQVAELELQLRSEQQK 686
Cdd:pfam07888  344 LEVELGREKdcnrvqlSESRRELQELKASLRVAQKEKEQLQAEKQELLEYIRQLEQR 400
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1045-1319 2.92e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 42.51  E-value: 2.92e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1045 FATLQEALAHALTEKEGKDQELAKLRGLEAAQIKELEELRQTVKQLKEQLAKKEKEHASGSGAQSEAAGRTEPTGPKLEA 1124
Cdd:COG3883      4 LALAAPTPAFADPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEE 83

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1125 LRAEVSKLEQQCQKQQEQADSLERSLEAERASRA-ERDSALETLQGQLEEKAQELGHSQSALASAQRELAAfrtKVQDHS 1203
Cdd:COG3883     84 RREELGERARALYRSGGSVSYLDVLLGSESFSDFlDRLSALSKIADADADLLEELKADKAELEAKKAELEA---KLAELE 160

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1204 KAEDEWKAQVARGRQEAERKNSLISSLEEEVSILNRQVLEKEGESKELKRLVMAESEKSQKLEERLRLLQAETASNSARA 1283
Cdd:COG3883    161 ALKAELEAAKAELEAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA 240

                          250       260       270
                   ....*....|....*....|....*....|....*.
gi 1370459521 1284 AERSSALREEVQSLREEAEKQRVASENLRQELTSQA 1319
Cdd:COG3883    241 AAAASAAGAGAAGAAGAAAGSAGAAGAAAGAAGAGA 276
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 970-1670 3.03e-03

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 42.80  E-value: 3.03e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  970 MEREAEQMGNELERLRAALMESQGQQQEERGQQEREVARLTQERGRAQadlaLEKAARAELEMRLQNALNEQRVEFATLQ 1049
Cdd:pfam15921   76 IERVLEEYSHQVKDLQRRLNESNELHEKQKFYLRQSVIDLQTKLQEMQ----MERDAMADIRRRESQSQEDLRNQLQNTV 151

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1050 EALAHALTEKE----GKDQELAKLRGLEAAQIKELEELRQTVKQLKEQLAKKEKEHASGSGAQSEAAGRTepTGPKLEAL 1125
Cdd:pfam15921  152 HELEAAKCLKEdmleDSNTQIEQLRKMMLSHEGVLQEIRSILVDFEEASGKKIYEHDSMSTMHFRSLGSA--ISKILREL 229

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1126 RAEVSKLEQQCQKQQEQADSLersleaerasRAERDSALETLQGQLEEKAQELghsqsaLASAQRELAAFRTKVQDHSKA 1205
Cdd:pfam15921  230 DTEISYLKGRIFPVEDQLEAL----------KSESQNKIELLLQQHQDRIEQL------ISEHEVEITGLTEKASSARSQ 293

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1206 EDEWKAQVARGRQEAERKNSL----ISSLEEEVSILNRQVLEK----EGESKEL-KRLVMAESEKSQKLEERLRLLQaET 1276
Cdd:pfam15921  294 ANSIQSQLEIIQEQARNQNSMymrqLSDLESTVSQLRSELREAkrmyEDKIEELeKQLVLANSELTEARTERDQFSQ-ES 372

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1277 ASNSARAAERSSAL--REEVQSLREEAEKQ--------RVASENLRQELTSQAERAEELGQELKAWQ-EKFFQKEQALST 1345
Cdd:pfam15921  373 GNLDDQLQKLLADLhkREKELSLEKEQNKRlwdrdtgnSITIDHLRRELDDRNMEVQRLEALLKAMKsECQGQMERQMAA 452

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1346 LQLEHTSTQAlVSELLPAKHLCQQLQAEQAAAEKRHREELEQSKQAAGGLRAELLRAQREL----GELIPLRQKVAEQER 1421
Cdd:pfam15921  453 IQGKNESLEK-VSSLTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIeatnAEITKLRSRVDLKLQ 531

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1422 TAQQLRAEKASY--------AEQLSMLKKAH-------------GLLAEENRGLGErANLGRQFLEVELDQAREKyVQEL 1480
Cdd:pfam15921  532 ELQHLKNEGDHLrnvqteceALKLQMAEKDKvieilrqqienmtQLVGQHGRTAGA-MQVEKAQLEKEINDRRLE-LQEF 609

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1481 AAVRADAETRLaevqREAQSTARELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQV-----------EQLEVFQREQTK 1549
Cdd:pfam15921  610 KILKDKKDAKI----RELEARVSDLELEKVKLVNAGSERLRAVKDIKQERDQLLNEVktsrnelnslsEDYEVLKRNFRN 685

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1550 QVEELSK-----KLADSDQASKVQQQK--LKAVQAQGGESQQEAQRLQAQLNELQAQLSQKEQAAEHYKLQMEKAKTHYD 1622
Cdd:pfam15921  686 KSEEMETttnklKMQLKSAQSELEQTRntLKSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKIQFLEEAMTNANKEKH 765

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1370459521 1623 AKKQQNQELQEQLRS-----------LEQLQKENKELRAEAERLGHELQQAGLKTKEAE 1670
Cdd:pfam15921  766 FLKEEKNKLSQELSTvateknkmageLEVLRSQERRLKEKVANMEVALDKASLQFAECQ 824
PRK11281 PRK11281
mechanosensitive channel MscK;
1045-1343 3.28e-03

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 42.59  E-value: 3.28e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1045 FATLQEALAHAL------TEKEGKDQ--ELAKLRGLEAAQIKELEELRQTVKQLkEQLAKKEKEhasgsgaqseaagrte 1116
Cdd:PRK11281    19 LLCLSSAFARAAsngdlpTEADVQAQldALNKQKLLEAEDKLVQQDLEQTLALL-DKIDRQKEE---------------- 81

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1117 ptgpkLEALRAEVSKLEQQCQKQQEQADSLERSLEAERASRAERDSaLETLQGQLEEKAQELGHSQSALASAQRELAAFR 1196
Cdd:PRK11281    82 -----TEQLKQQLAQAPAKLRQAQAELEALKDDNDEETRETLSTLS-LRQLESRLAQTLDQLQNAQNDLAEYNSQLVSLQ 155

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1197 T---KVQ----DHSKAEDEWKAQVARGRQEAERKN-SLISSLEEEVSILN------RQVLEKEGESKELKRLVMAE-SEK 1261
Cdd:PRK11281   156 TqpeRAQaalyANSQRLQQIRNLLKGGKVGGKALRpSQRVLLQAEQALLNaqndlqRKSLEGNTQLQDLLQKQRDYlTAR 235

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1262 SQKLEERLRLLQaeTASNSARAAErSSALREEVQSLREEAEKQR---VASEN-----LRQELTSQAERAEELGQE---LK 1330
Cdd:PRK11281   236 IQRLEHQLQLLQ--EAINSKRLTL-SEKTVQEAQSQDEAARIQAnplVAQELeinlqLSQRLLKATEKLNTLTQQnlrVK 312

                          330
                   ....*....|...
gi 1370459521 1331 AWQEKFFQKEQAL 1343
Cdd:PRK11281   313 NWLDRLTQSERNI 325
PRK10929 PRK10929
putative mechanosensitive channel protein; Provisional
 360-734 3.52e-03

putative mechanosensitive channel protein; Provisional


Pssm-ID: 236798 [Multi-domain]  Cd Length: 1109  Bit Score: 42.73  E-value: 3.52e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  360 AQLEKELSAALQDKKCLE-EKNEILQGKLSQLEEHLSQLQ---------DNPPQEKGEVLGdvlQLETLKQEAATLAANN 429
Cdd:PRK10929    26 KQITQELEQAKAAKTPAQaEIVEALQSALNWLEERKGSLErakqyqqviDNFPKLSAELRQ---QLNNERDEPRSVPPNM 102

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  430 TqlqarVEMLETERGQQEAKLLaERGHFEEEKQQLSSLITDlqsSISNLSQAKEELEQASQAHGARLTAQVASLTSELTT 509
Cdd:PRK10929   103 S-----TDALEQEILQVSSQLL-EKSRQAQQEQDRAREISD---SLSQLPQQQTEARRQLNEIERRLQTLGTPNTPLAQA 173

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  510 LNATIQQqdqELAGLKQQAKEKqaqlaqtlqqqeqasqglrhQVEQLSSSLKQKEQQLK-EVAEKQEATRQDHAQQLata 588
Cdd:PRK10929   174 QLTALQA---ESAALKALVDEL--------------------ELAQLSANNRQELARLRsELAKKRSQQLDAYLQAL--- 227

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  589 aEEREASLRERDA--ALKQLEALEKEKAAKLEILQQQLQVAneaRDSAQTSVTQAQREKAELSRKveeLQACVET--ARQ 664
Cdd:PRK10929   228 -RNQLNSQRQREAerALESTELLAEQSGDLPKSIVAQFKIN---RELSQALNQQAQRMDLIASQQ---RQAASQTlqVRQ 300

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  665 ------EQH----------EA-QAQVAELELQLRSeQQKATE--KERVAQEK-DQLQEQLQALKESLKVTKGSLEEEKRR 724
Cdd:PRK10929   301 alntlrEQSqwlgvsnalgEAlRAQVARLPEMPKP-QQLDTEmaQLRVQRLRyEDLLNKQPQLRQIRQADGQPLTAEQNR 379

                          410
                   ....*....|
gi 1370459521  725 AADALEEQQR 734
Cdd:PRK10929   380 ILDAQLRTQR 389
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 494-699 3.54e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 42.12  E-value: 3.54e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  494 ARLTAQVASLTSELTTLNATIQQQDQELaglkQQAKEKQAQLAQTLQQQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEK 573
Cdd:COG3883     19 QAKQKELSELQAELEAAQAELDALQAEL----EELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARA 94

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  574 QEATRQ------------------DHAQQLATAAEEREASLRERDAALKQLEALEKEKAAKLEILQQQLQVANEARDSAQ 635
Cdd:COG3883     95 LYRSGGsvsyldvllgsesfsdflDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAELE 174

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1370459521  636 TSVTQAQREKAELSRKVEELQACVETARQEQHEAQAQVAELELQLRSEQQKATEKERVAQEKDQ 699
Cdd:COG3883    175 AQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAAAA 238
YqiK COG2268
Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain [Function unknown];
606-812 4.25e-03

Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain [Function unknown];


Pssm-ID: 441869 [Multi-domain]  Cd Length: 439  Bit Score: 41.78  E-value: 4.25e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  606 LEALEKEKAAklEILQQQLQVANEARDSAQTSVTQAQREK--AELSRKVEelqacVETARQEQHEAQAQVAELELQLRSE 683
Cdd:COG2268    186 LDALGRRKIA--EIIRDARIAEAEAERETEIAIAQANREAeeAELEQERE-----IETARIAEAEAELAKKKAEERREAE 258

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  684 QQKATEKERVAQEKDQLQEQLQALKESLKVTKGSLEEEKRRAADalEEQQRCISELKAETRSLVEQhkrerkelEEERAG 763
Cdd:COG2268    259 TARAEAEAAYEIAEANAEREVQRQLEIAEREREIELQEKEAERE--EAELEADVRKPAEAEKQAAE--------AEAEAE 328

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*....
gi 1370459521  764 RKGLEARLQQLGEAHQAETEVLrRELAEAMAAQHTAESeCEQLVKEVAA 812
Cdd:COG2268    329 AEAIRAKGLAEAEGKRALAEAW-NKLGDAAILLMLIEK-LPEIAEAAAK 375
ClpA COG0542
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ...
 1144-1270 4.33e-03

ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440308 [Multi-domain]  Cd Length: 836  Bit Score: 42.38  E-value: 4.33e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1144 DSLERSLEAERAsraERDSALETLQGQLEEKAQELghsQSALASAQRELAAFRTKVQdhskAEDEWKAQVARGRQEAERK 1223
Cdd:COG0542    414 DELERRLEQLEI---EKEALKKEQDEASFERLAEL---RDELAELEEELEALKARWE----AEKELIEEIQELKEELEQR 483

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1370459521 1224 NSLISSLEEEVSILNRQVLEKEGESKE------------------LKRLVMAESEKSQKLEERLR 1270
Cdd:COG0542    484 YGKIPELEKELAELEEELAELAPLLREevteediaevvsrwtgipVGKLLEGEREKLLNLEEELH 548
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1144-1328 4.73e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 41.67  E-value: 4.73e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1144 DSLERSLEAERASRAERDSALETLQGQLEEKAQELGHSQSALASAQRELAAFRTKVQDHSKAEDEWKAQVARGRQEAERk 1223
Cdd:COG4942     37 AELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELAELLRALYR- 115

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1224 NSLISSLEEEVSILNRQVLEKEGES-KELKRLVMAESEKSQKLEERLRLLQAETASNSARAAERSSALREEVQSLREEAE 1302
Cdd:COG4942    116 LGRQPPLALLLSPEDFLDAVRRLQYlKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAELEEERAALEALKA 195

                          170       180
                   ....*....|....*....|....*.
gi 1370459521 1303 KQRVASENLRQELTSQAERAEELGQE 1328
Cdd:COG4942    196 ERQKLLARLEKELAELAAELAELQQE 221
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 1163-1305 4.82e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 41.06  E-value: 4.82e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1163 ALETLQGQLEEKAQELGHSQSALASAQRELAAFRTKVQDHSKAEDEWKAQVAR--GRQEAERKNSLISSLEEEVSILNRQ 1240
Cdd:COG1579     25 RLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKyeEQLGNVRNNKEYEALQKEIESLKRR 104

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1370459521 1241 VLEKEGESKELKRLVMAESEKSQKLEERLRLLQAETASNSARAAERSSALREEVQSLREEAEKQR 1305
Cdd:COG1579    105 ISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAEREELA 169
hsdR PRK11448
type I restriction enzyme EcoKI subunit R; Provisional
 564-655 5.58e-03

type I restriction enzyme EcoKI subunit R; Provisional


Pssm-ID: 236912 [Multi-domain]  Cd Length: 1123  Bit Score: 41.86  E-value: 5.58e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  564 EQQLKEVAEKQEATRQDhAQQLATAAEEREASLRERDAALKQLEALEKEKAAKLEILQQQLQVANEARDSAQTSVTQAQR 643
Cdd:PRK11448   141 ENLLHALQQEVLTLKQQ-LELQAREKAQSQALAEAQQQELVALEGLAAELEEKQQELEAQLEQLQEKAAETSQERKQKRK 219

                           90
                   ....*....|..
gi 1370459521  644 EKAELSRKVEEL 655
Cdd:PRK11448   220 EITDQAAKRLEL 231
CALCOCO1 pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
 508-860 5.82e-03

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 41.42  E-value: 5.82e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  508 TTLNATIQQQDQELAGLKQQAKEKQAQLAQTLQQQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEATRQDHAQQLAT 587
Cdd:pfam07888   30 ELLQNRLEECLQERAELLQAQEAANRQREKEKERYKRDREQWERQRRELESRVAELKEELRQSREKHEELEEKYKELSAS 109

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  588 A---AEEREASLRERDAALKQLEALEKEKAAKLEILQQQLQVANEARDSAQTSVTQAQREKAELSRKVEELQACVETAR- 663
Cdd:pfam07888  110 SeelSEEKDALLAQRAAHEARIRELEEDIKTLTQRVLERETELERMKERAKKAGAQRKEEEAERKQLQAKLQQTEEELRs 189

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  664 -----QEQHEAQAQVAELELQLRSE----QQKATEKERVAQEKDQLQEQLQALKESLKVTKGSLEEEKRRAADALEEQQR 734
Cdd:pfam07888  190 lskefQELRNSLAQRDTQVLQLQDTittlTQKLTTAHRKEAENEALLEELRSLQERLNASERKVEGLGEELSSMAAQRDR 269

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  735 CISEL---KAETRSLVEQHKRERKELEEERAGRKGLEARLQQLGEAHQAETEVLRRELAEAMAAQHTAESECEQLVKEVA 811
Cdd:pfam07888  270 TQAELhqaRLQAAQLTLQLADASLALREGRARWAQERETLQQSAEADKDRIEKLSAELQRLEERLQEERMEREKLEVELG 349

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*....
gi 1370459521  812 AWRERYEDSQQEEAQYGAMFQEQLMTLKEECEKARQELQEAKEKVAGIE 860
Cdd:pfam07888  350 REKDCNRVQLSESRRELQELKASLRVAQKEKEQLQAEKQELLEYIRQLE 398
Crescentin pfam19220
Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament ...
 553-876 5.95e-03

Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament proteins, named crescentin, whose cytoskeletal function is required for the vibrioid and helical shapes of Caulobacter crescentus. Without crescentin, the cells adopt a straight-rod morphology. Crescentin has characteriztic features of IF proteins including the ability to assemble into filaments in vitro without energy or cofactor requirements. In vivo, crescentin forms a helical structure that colocalizes with the inner cell curvatures beneath the cytoplasmic membrane.


Pssm-ID: 437057 [Multi-domain]  Cd Length: 401  Bit Score: 41.21  E-value: 5.95e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  553 VEQLSSSLKQKEQQLKEVAEKQEATRQDHAQQLATAAEEREASLRERDAALKQLEALEKEKAAkleiLQQQLQVANEARD 632
Cdd:pfam19220   81 AEGELEELVARLAKLEAALREAEAAKEELRIELRDKTAQAEALERQLAAETEQNRALEEENKA----LREEAQAAEKALQ 156

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  633 SAQTSVTQAQREKAELSRKVEELQACVETARQEQHEAQAQVAELELQLRSEQQK--ATEKERVAQ--EKDQLQEQLQALK 708
Cdd:pfam19220  157 RAEGELATARERLALLEQENRRLQALSEEQAAELAELTRRLAELETQLDATRARlrALEGQLAAEqaERERAEAQLEEAV 236

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  709 ESLKVTKGSLEEEKRRAADALEEQQRCISELKAETRSLVEQHKRERKELEEERAGRKGLEARLQQLgeahQAETEVLRRE 788
Cdd:pfam19220  237 EAHRAERASLRMKLEALTARAAATEQLLAEARNQLRDRDEAIRAAERRLKEASIERDTLERRLAGL----EADLERRTQQ 312

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  789 LAEAMAAQHTAESECEQLVKEVAAwreryEDSQQEEA-QYGAMFQEQLMTLKEECEKARQELQEAKEKVAgieshSELQI 867
Cdd:pfam19220  313 FQEMQRARAELEERAEMLTKALAA-----KDAALERAeERIASLSDRIAELTKRFEVERAALEQANRRLK-----EELQR 382


                   ....*....
gi 1370459521  868 SRQQNELAE 876
Cdd:pfam19220  383 ERAERALAQ 391
PRK10929 PRK10929
putative mechanosensitive channel protein; Provisional
 1170-1346 6.04e-03

putative mechanosensitive channel protein; Provisional


Pssm-ID: 236798 [Multi-domain]  Cd Length: 1109  Bit Score: 41.96  E-value: 6.04e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1170 QLEEKAQELGHSQSAL----ASAQRELAAFRTKVQDHSKAED-EWKAQVARGRQEAERKNSLISSLE-EEVSILNRQvle 1243
Cdd:PRK10929   127 QEQDRAREISDSLSQLpqqqTEARRQLNEIERRLQTLGTPNTpLAQAQLTALQAESAALKALVDELElAQLSANNRQ--- 203

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1244 kegeskELKRLvmaESEKSQKLEERLRLLQAETASN--------SARAAERSSALREEVQSLREEAEKQRVASENLRQEL 1315
Cdd:PRK10929   204 ------ELARL---RSELAKKRSQQLDAYLQALRNQlnsqrqreAERALESTELLAEQSGDLPKSIVAQFKINRELSQAL 274

                          170       180       190
                   ....*....|....*....|....*....|.
gi 1370459521 1316 TSQAERAEELGQELKAWQEKFFQKEQALSTL 1346
Cdd:PRK10929   275 NQQAQRMDLIASQQRQAASQTLQVRQALNTL 305
Surf_Exclu_PgrA TIGR04320
SEC10/PgrA surface exclusion domain; This model describes a conserved domain found in surface ...
 419-531 7.36e-03

SEC10/PgrA surface exclusion domain; This model describes a conserved domain found in surface proteins of a number of Firmutes. Many members have LPXTG C-terminal anchoring motifs and a substantial number have the KxYKxGKxW putative sorting signal at the N-terminus. The tetracycline resistance plasmid pCF10 in Enterococcus faecalis promotes conjugal plasmid transfer in response to sex pheromones, but PgrA/Sec10 encoded by that plasmid, a member of this family, specifically inhibits the ability of cells to receive homologous plasmids. The phenomenon is called surface exclusion.


Pssm-ID: 275124 [Multi-domain]  Cd Length: 356  Bit Score: 40.87  E-value: 7.36e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  419 KQEAATLAANNTQLQARVEmletergQQEAKLLAERGHFEEEKQQLSSLITDLQSSISNLSQAKEELEQASQAHGARLTA 498
Cdd:TIGR04320  246 KTPIPNPPNSLAALQAKLA-------TAQADLAAAQTALNTAQAALTSAQTAYAAAQAALATAQKELANAQAQALQTAQN 318

                           90       100       110
                   ....*....|....*....|....*....|...
gi 1370459521  499 QVASLTSELTTLNATIQQQDQELAGLKQQAKEK 531
Cdd:TIGR04320  319 NLATAQAALANAEARLAKAKEALANLNADLAKK 351
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
226-346 7.78e-03

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 41.38  E-value: 7.78e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  226 ERSNRDELELELAENRKLLTEKDAQIAMMQQRIDRLAllnekqaasplepKELEELRDKNESLTMRLHETLKQCQDLKTE 305
Cdd:COG2433    383 EELIEKELPEEEPEAEREKEHEERELTEEEEEIRRLE-------------EQVERLEAEVEELEAELEEKDERIERLERE 449

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1370459521  306 KSQM----------DRKINQLSEENGDLSFKLREFASHLQQLQDALNELTE 346
Cdd:COG2433    450 LSEArseerreirkDREISRLDREIERLERELEEERERIEELKRKLERLKE 500
hsdR PRK11448
type I restriction enzyme EcoKI subunit R; Provisional
 653-749 7.82e-03

type I restriction enzyme EcoKI subunit R; Provisional


Pssm-ID: 236912 [Multi-domain]  Cd Length: 1123  Bit Score: 41.48  E-value: 7.82e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  653 EELQACVETARQEQHEAQAQVAELELQLRSEQQKATEKERVAQE----KDQLQEQLQALKE-SLKVTKGSLEEEKRRAAD 727
Cdd:PRK11448   145 HALQQEVLTLKQQLELQAREKAQSQALAEAQQQELVALEGLAAEleekQQELEAQLEQLQEkAAETSQERKQKRKEITDQ 224

                           90       100
                   ....*....|....*....|..
gi 1370459521  728 ALEEQQrcISElkAETRSLVEQ 749
Cdd:PRK11448   225 AAKRLE--LSE--EETRILIDQ 242
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1016-1197 8.04e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 41.16  E-value: 8.04e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1016 AQADLALEKAARAELEMRLQNALNEQRVEFATLQEALAHALTEKEGKDQELAKLRGLEAAQIKELEELRQ--TVKQLKEQ 1093
Cdd:COG3206    192 EEAEAALEEFRQKNGLVDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLGSGPDALPELLQspVIQQLRAQ 271

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1094 LAKKEKEHAsgsgaqsEAAGRTEPTGPKLEALRAEVSKLEQQCQKQqeqADSLERSLEAERASRAERDSALETLQGQLEE 1173
Cdd:COG3206    272 LAELEAELA-------ELSARYTPNHPDVIALRAQIAALRAQLQQE---AQRILASLEAELEALQAREASLQAQLAQLEA 341

                          170       180
                   ....*....|....*....|....
gi 1370459521 1174 KAQELGHSQSALASAQRELAAFRT 1197
Cdd:COG3206    342 RLAELPELEAELRRLEREVEVARE 365
CusB_dom_1 pfam00529
Cation efflux system protein CusB domain 1; The cation efflux system protein CusB from E. coli ...
 404-562 8.32e-03

Cation efflux system protein CusB domain 1; The cation efflux system protein CusB from E. coli can be divided into four different domains, the first three domains of the protein are mostly beta-strands and the fourth forms an all alpha-helical domain. This entry represents the first beta-domain (domain 1) of CusB and it is formed by the N and C-terminal ends of the polypeptide (residues 89-102 and 324-385). CusB is part of the copper-transporting efflux system CusCFBA. This domain can also be found in other membrane-fusion proteins, such as HlyD, MdtN, MdtE and AaeA. HlyD is a component of the prototypical alpha-haemolysin (HlyA) bacterial type I secretion system, along with the other components HlyB and TolC. HlyD is anchored in the cytoplasmic membrane by a single transmembrane domain and has a large periplasmic domain within the carboxy-terminal 100 amino acids, HlyB and HlyD form a stable complex that binds the recombinant protein bearing a C-terminal HlyA signal sequence and ATP in the cytoplasm. HlyD, HlyB and TolC combine to form the three-component ABC transporter complex that forms a trans-membrane channel or pore through which HlyA can be transferred directly to the extracellular medium. Cutinase has been shown to be transported effectively through this pore.


Pssm-ID: 425733 [Multi-domain]  Cd Length: 322  Bit Score: 40.87  E-value: 8.32e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  404 EKGEVLgdvLQLE--TLKQEAATLAANNTQLQARVEMLETERGQQEAKLLAERGhfeeEKQQLSSLITDLQSSISNLSQA 481
Cdd:pfam00529   43 KAGDVL---FQLDptDYQAALDSAEAQLAKAQAQVARLQAELDRLQALESELAI----SRQDYDGATAQLRAAQAAVKAA 115

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  482 KEELEQA-SQAHGARLTAQV------------ASLTSELTTLNATIQQQDQELAGLKQQAKEKQAQLAQTLQQQEQASQG 548
Cdd:pfam00529  116 QAQLAQAqIDLARRRVLAPIggisreslvtagALVAQAQANLLATVAQLDQIYVQITQSAAENQAEVRSELSGAQLQIAE 195

                          170
                   ....*....|....
gi 1370459521  549 LRHQVEQLSSSLKQ 562
Cdd:pfam00529  196 AEAELKLAKLDLER 209
valS PRK05729
valyl-tRNA synthetase; Reviewed
 1465-1598 8.32e-03

valyl-tRNA synthetase; Reviewed


Pssm-ID: 235582 [Multi-domain]  Cd Length: 874  Bit Score: 41.24  E-value: 8.32e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1465 LEVELDQAREKYVQELAAVRADAE--TRLAEVQREAQSTARELEVMTAKYEGAKVKV-LE-------ERQRFQEERQKLT 1534
Cdd:PRK05729   745 LPLLLKGADAEDRARLEANEAYIKrlARLESLEILADDEEAPEGAASAVVGGAELFLpLEglidveaELARLEKELAKLE 824

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1370459521 1535 AQVEQLEvfqreqtkqveelsKKLADSDQASKVQQQKLKAVQAQGGESQQEAQRLQAQLNELQA 1598
Cdd:PRK05729   825 KEIERVE--------------KKLSNEGFVAKAPEEVVEKEREKLAEYEEKLAKLKERLARLKA 874
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
559-785 8.55e-03

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 40.66  E-value: 8.55e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  559 SLKQKEQQLKEVAEKQEATRQDHAQQLATAAEEREASLRERDAALKQLEALEKE---KAAKLEILQQQLQVANEARDSAQ 635
Cdd:COG4372     14 SLFGLRPKTGILIAALSEQLRKALFELDKLQEELEQLREELEQAREELEQLEEEleqARSELEQLEEELEELNEQLQAAQ 93

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  636 TSVTQAQREKAELSRKVEELQACVETARQEQHEAQAQVAELELQLRSEQQKATEKERVAQEKDQLQEQLQALKESLKVTK 715
Cdd:COG4372     94 AELAQAQEELESLQEEAEELQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALEQEL 173

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1370459521  716 GSLEEEK-RRAADALEEQQRCISELKAETRSLVEQHKRERKELEEERAGRKGLEARLQQLGEAHQAETEVL 785
Cdd:COG4372    174 QALSEAEaEQALDELLKEANRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKLGLALSALLDALEL 244
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1549-1697 8.74e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 41.29  E-value: 8.74e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1549 KQVEELSKKLadsdQASKVQQQKLKAVQAQGGESQQEAQRLQAQLNELQAQLSQKEQAAEHYKL--QMEKAKTHYDAKKQ 1626
Cdd:COG4717     71 KELKELEEEL----KEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLyqELEALEAELAELPE 146

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1370459521 1627 QNQELQEQLRSLEQLQKENKELRAEAERLGHELQQAGLKTK-EAEQTCRHLTAQVRSLEAQVAHADQQLRDL 1697
Cdd:COG4717    147 RLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSlATEEELQDLAEELEELQQRLAELEEELEEA 218
MARTX_Nterm NF012221
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...
 1415-1675 9.12e-03

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.


Pssm-ID: 467957 [Multi-domain]  Cd Length: 1848  Bit Score: 41.36  E-value: 9.12e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1415 KVAEQERTAQQLRAEKASYAEQLSMLKKahgllaEENRGLGERAnlGRQF-LEVELDQAREKYVQ-ELAAVRADAEtrla 1492
Cdd:NF012221  1549 KHAKQDDAAQNALADKERAEADRQRLEQ------EKQQQLAAIS--GSQSqLESTDQNALETNGQaQRDAILEESR---- 1616

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1493 EVQREAQSTARELEVMTAKYEGAKVKVLEERQRFQEeRQKLTAQvEQLEVFQREQTKQVEELSKKLADSDQASKVQQQKL 1572
Cdd:NF012221  1617 AVTKELTTLAQGLDALDSQATYAGESGDQWRNPFAG-GLLDRVQ-EQLDDAKKISGKQLADAKQRHVDNQQKVKDAVAKS 1694

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521 1573 KAVQAQGGESQQEAQrLQAQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQELQeqlrslEQLQKENKELRAEA 1652
Cdd:NF012221  1695 EAGVAQGEQNQANAE-QDIDDAKADAEKRKDDALAKQNEAQQAESDANAAANDAQSRGEQ------DASAAENKANQAQA 1767

                          250       260
                   ....*....|....*....|...
gi 1370459521 1653 ErlghelqQAGLKTKEAEQTCRH 1675
Cdd:NF012221  1768 D-------AKGAKQDESDKPNRQ 1783
Crescentin pfam19220
Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament ...
 387-772 9.22e-03

Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament proteins, named crescentin, whose cytoskeletal function is required for the vibrioid and helical shapes of Caulobacter crescentus. Without crescentin, the cells adopt a straight-rod morphology. Crescentin has characteriztic features of IF proteins including the ability to assemble into filaments in vitro without energy or cofactor requirements. In vivo, crescentin forms a helical structure that colocalizes with the inner cell curvatures beneath the cytoplasmic membrane.


Pssm-ID: 437057 [Multi-domain]  Cd Length: 401  Bit Score: 40.82  E-value: 9.22e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  387 LSQLEEHLSQLQDNPPQEKGEVLGDVLQLETLKQEAATLAANNTQLQARVEMLETERGQQEAKLLAERGHFEEEKQQLSS 466
Cdd:pfam19220   50 LLELEALLAQERAAYGKLRRELAGLTRRLSAAEGELEELVARLAKLEAALREAEAAKEELRIELRDKTAQAEALERQLAA 129

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  467 ------LITDLQSSISNLSQAKEELEQASQAHGARLTAQVASLTSELTTLNATIQQQDQELAGLKQQAKEkqaqlaqtlq 540
Cdd:pfam19220  130 eteqnrALEEENKALREEAQAAEKALQRAEGELATARERLALLEQENRRLQALSEEQAAELAELTRRLAE---------- 199

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  541 qqeqasqglrhqveqLSSSLKQKEQQLKEVAEKQEATRQDHAQQLATAAEEREASLRERDAALKQLEALEKEKAAKLEIL 620
Cdd:pfam19220  200 ---------------LETQLDATRARLRALEGQLAAEQAERERAEAQLEEAVEAHRAERASLRMKLEALTARAAATEQLL 264

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  621 QQ---QLQVANEARDSAQTSVTQAQREKAELSRKVEELQAcvETARQEQHEAQAQVAELELQLRSE------QQKATEKE 691
Cdd:pfam19220  265 AEarnQLRDRDEAIRAAERRLKEASIERDTLERRLAGLEA--DLERRTQQFQEMQRARAELEERAEmltkalAAKDAALE 342

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  692 RVAQEKDQLQEQLQALKESLKVTKGSLEEEKRRAADALEeqqrciselkaetrslveqhkrerkeleEERAGRKGLEARL 771
Cdd:pfam19220  343 RAEERIASLSDRIAELTKRFEVERAALEQANRRLKEELQ----------------------------RERAERALAQGAL 394


                   .
gi 1370459521  772 Q 772
Cdd:pfam19220  395 E 395
ClpA COG0542
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ...
 647-742 9.27e-03

ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440308 [Multi-domain]  Cd Length: 836  Bit Score: 41.22  E-value: 9.27e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  647 ELSRKVEELQACVETARQEQHEA-QAQVAELELQLRSEQQKATEKERVAQEKDQLQEQLQALKESLKVTKGSLEEEKRRA 725
Cdd:COG0542    415 ELERRLEQLEIEKEALKKEQDEAsFERLAELRDELAELEEELEALKARWEAEKELIEEIQELKEELEQRYGKIPELEKEL 494

                           90
                   ....*....|....*..
gi 1370459521  726 ADALEEQQRCISELKAE 742
Cdd:COG0542    495 AELEEELAELAPLLREE 511
MAP65_ASE1 pfam03999
Microtubule associated protein (MAP65/ASE1 family);
549-742 9.82e-03

Microtubule associated protein (MAP65/ASE1 family);


Pssm-ID: 427641 [Multi-domain]  Cd Length: 477  Bit Score: 40.76  E-value: 9.82e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  549 LRHQVEQLSSSLKQKEQQLKEVAEKQEATRQDHAQQLATAAEEREASLRERDAALKQLEALEKEKAAKLE----ILQQQL 624
Cdd:pfam03999   95 LDTQLEHLRKEKAPRLAEIKELLEQLQQLCEELGEEPLPLLIDPLPSLEELESFRKHLENLRNEKERRLEevneLKKQIK 174

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1370459521  625 QVANEARDSAQTSVTQAQREKAELSRKVEelQACVETARQEQHEAQAQVAELElqlrseqqkatekervaQEKDQLQEQL 704
Cdd:pfam03999  175 LLMEELDLVPGTDFEEDLLCESEDNFCLS--RENIDKLRKLIKQLEEQKAERE-----------------EKIDDLREKI 235

                          170       180       190
                   ....*....|....*....|....*....|....*...
gi 1370459521  705 QALKESLKVtkgSLEEEKRRAADALEEQQRCISELKAE 742
Cdd:pfam03999  236 LELWNRLQV---PQEEQESFVRENNSLSQDTIDALREE 270
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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