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Conserved domains on  [gi|1720365910|ref|XP_030101822|]
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zinc finger protein 454 isoform X1 [Mus musculus]

Protein Classification

C2H2-type zinc finger protein( domain architecture ID 11472214)

Cys2His2 (C2H2)-type zinc finger protein may be involved in transcriptional regulation

CATH:  3.30.160.60
Gene Ontology:  GO:0008270|GO:0003677
PubMed:  11361095|22803940
SCOP:  4003583

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
135-447 1.27e-09

FOG: Zn-finger [General function prediction only];


:

Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 60.09  E-value: 1.27e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720365910 135 SQKSPMKEKRYKCRECGKAFHQSTHLIHHQRVHTGEKPYQCKD--CGKAFSVSSSLSYHQKIHTGEKPFECNVCG----- 207
Cdd:COG5048    24 LKSLSNAPRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYsgCDKSFSRPLELSRHLRTHHNNPSDLNSKSLplsns 103

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720365910 208 KAFIRNIHLSHHHRMhTGEKPFQCNLCDKAFVcRAHLTKHQHIHSGKKPYK-CNECGKAFNQSTSFLQ------------ 274
Cdd:COG5048   104 KASSSSLSSSSSNSN-DNNLLSSHSLPPSSRD-PQLPDLLSISNLRNNPLPgNNSSSVNTPQSNSLHPplpanslskdps 181

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720365910 275 -------HQRIHTGEKPFECNECGKAFRVNSSLTEHQRIHTGEKPYQCIECGKAFRDNSSFARHRKIHTGEKPYRCGLCE 347
Cdd:COG5048   182 snlslliSSNVSTSIPSSSENSPLSSSYSIPSSSSDQNLENSSSSLPLTTNSQLSPKSLLSQSPSSLSSSDSSSSASESP 261

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720365910 348 KAFR--DQSALAQHQRTHTGE-----KPYTCNICEKAFSDHSALTQHKR--IHTRE--KPYKC--KTCGKAFIRSTHLIQ 414
Cdd:COG5048   262 RSSLptASSQSSSPNESDSSSekgfsLPIKSKQCNISFSRSSPLTRHLRsvNHSGEslKPFSCpySLCGKLFSRNDALKR 341

                         330       340       350
                  ....*....|....*....|....*....|....*
gi 1720365910 415 HQRIHTGEKPYKC--NTCGKAFNQTANLAQHQRHH 447
Cdd:COG5048   342 HILLHTSISPAKEklLNSSSKFSPLLNNEPPQSLQ 376
 
Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
135-447 1.27e-09

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 60.09  E-value: 1.27e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720365910 135 SQKSPMKEKRYKCRECGKAFHQSTHLIHHQRVHTGEKPYQCKD--CGKAFSVSSSLSYHQKIHTGEKPFECNVCG----- 207
Cdd:COG5048    24 LKSLSNAPRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYsgCDKSFSRPLELSRHLRTHHNNPSDLNSKSLplsns 103

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720365910 208 KAFIRNIHLSHHHRMhTGEKPFQCNLCDKAFVcRAHLTKHQHIHSGKKPYK-CNECGKAFNQSTSFLQ------------ 274
Cdd:COG5048   104 KASSSSLSSSSSNSN-DNNLLSSHSLPPSSRD-PQLPDLLSISNLRNNPLPgNNSSSVNTPQSNSLHPplpanslskdps 181

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720365910 275 -------HQRIHTGEKPFECNECGKAFRVNSSLTEHQRIHTGEKPYQCIECGKAFRDNSSFARHRKIHTGEKPYRCGLCE 347
Cdd:COG5048   182 snlslliSSNVSTSIPSSSENSPLSSSYSIPSSSSDQNLENSSSSLPLTTNSQLSPKSLLSQSPSSLSSSDSSSSASESP 261

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720365910 348 KAFR--DQSALAQHQRTHTGE-----KPYTCNICEKAFSDHSALTQHKR--IHTRE--KPYKC--KTCGKAFIRSTHLIQ 414
Cdd:COG5048   262 RSSLptASSQSSSPNESDSSSekgfsLPIKSKQCNISFSRSSPLTRHLRsvNHSGEslKPFSCpySLCGKLFSRNDALKR 341

                         330       340       350
                  ....*....|....*....|....*....|....*
gi 1720365910 415 HQRIHTGEKPYKC--NTCGKAFNQTANLAQHQRHH 447
Cdd:COG5048   342 HILLHTSISPAKEklLNSSSKFSPLLNNEPPQSLQ 376
zf-H2C2_2 pfam13465
Zinc-finger double domain;
411-436 3.18e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 37.74  E-value: 3.18e-04
                          10        20
                  ....*....|....*....|....*.
gi 1720365910 411 HLIQHQRIHTGEKPYKCNTCGKAFNQ 436
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
SUF4-like cd20908
N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), ...
 395-448 7.88e-04

N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana SUF4 (AtSUF4), and similar proteins; Oryza sativa SUPPRESSOR OF FRI 4 (OsSUF4) is a C2H2-type zinc finger transcription factor which interacts with the major H3K36 methyltransferase SDG725 to promote H3K36me3 (tri-methylation at H3K9) establishment. The transcription factor OsSUF4 recognizes a specific 7-bp DNA element (5'-CGGAAAT-3'), which is contained in the promoter regions of many genes throughout the rice genome. Through interaction with OsSUF4, SDG725 is recruited to the promoters of key florigen genes, RICE FLOWERING LOCUS T1 (RFT1) and Heading date 3a (Hd3a), for H3K36 deposition to promote gene activation and rice plant flowering. OsSUF4 target genes include a number of genes involved in many biological processes. Flowering plant Arabidopsis SUF4 binds to a 15bp DNA element (5'-CCAAATTTTAAGTTT-3') within the promoter of the floral repressor gene FLOWERING LOCUS C (FLC) and recruits the FRI-C transcription activator complex to the FLC promoter. Although the DNA-binding element and target genes of AtSUF4 are different from those of OsSUF4, AtSUF4 is known to interact with the Arabidopsis H3K36 methyltransferase SDG8 (also known as ASHH2/EFS/SET8), and the methylation deposition mechanism mediated by the SUF4 transcription factor and H3K36 methyltransferase may be conserved in Arabidopsis and rice. Proteins in this family have two conserved C2H2-type zinc finger motifs at the N-terminus (included in this model), and a large proline-rich domain at the C-terminus; for OsSUF4, it has been shown that the N-terminal zinc-finger domain is responsible for DNA binding, and that the C-terminal domain interacts with SDG725.


Pssm-ID: 411020 [Multi-domain]  Cd Length: 82  Bit Score: 38.31  E-value: 7.88e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1720365910 395 KPYkCKTCGKAFIRSTHLIQHQRIHTgekpYKCNTCGKAFNQTANLAQH--QRHHT 448
Cdd:cd20908     1 KPW-CYYCDREFDDEKILIQHQKAKH----FKCHICHKKLYTAGGLAVHclQVHKE 51
PHA00733 PHA00733
hypothetical protein
 368-415 7.12e-03

hypothetical protein


Pssm-ID: 177301  Cd Length: 128  Bit Score: 36.78  E-value: 7.12e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 1720365910 368 PYTCNICEKAFSDHSALTQHKRIHTREKpyKCKTCGKAFIRSTHLIQH 415
Cdd:PHA00733   73 PYVCPLCLMPFSSSVSLKQHIRYTEHSK--VCPVCGKEFRNTDSTLDH 118
 
Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
135-447 1.27e-09

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 60.09  E-value: 1.27e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720365910 135 SQKSPMKEKRYKCRECGKAFHQSTHLIHHQRVHTGEKPYQCKD--CGKAFSVSSSLSYHQKIHTGEKPFECNVCG----- 207
Cdd:COG5048    24 LKSLSNAPRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYsgCDKSFSRPLELSRHLRTHHNNPSDLNSKSLplsns 103

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720365910 208 KAFIRNIHLSHHHRMhTGEKPFQCNLCDKAFVcRAHLTKHQHIHSGKKPYK-CNECGKAFNQSTSFLQ------------ 274
Cdd:COG5048   104 KASSSSLSSSSSNSN-DNNLLSSHSLPPSSRD-PQLPDLLSISNLRNNPLPgNNSSSVNTPQSNSLHPplpanslskdps 181

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720365910 275 -------HQRIHTGEKPFECNECGKAFRVNSSLTEHQRIHTGEKPYQCIECGKAFRDNSSFARHRKIHTGEKPYRCGLCE 347
Cdd:COG5048   182 snlslliSSNVSTSIPSSSENSPLSSSYSIPSSSSDQNLENSSSSLPLTTNSQLSPKSLLSQSPSSLSSSDSSSSASESP 261

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720365910 348 KAFR--DQSALAQHQRTHTGE-----KPYTCNICEKAFSDHSALTQHKR--IHTRE--KPYKC--KTCGKAFIRSTHLIQ 414
Cdd:COG5048   262 RSSLptASSQSSSPNESDSSSekgfsLPIKSKQCNISFSRSSPLTRHLRsvNHSGEslKPFSCpySLCGKLFSRNDALKR 341

                         330       340       350
                  ....*....|....*....|....*....|....*
gi 1720365910 415 HQRIHTGEKPYKC--NTCGKAFNQTANLAQHQRHH 447
Cdd:COG5048   342 HILLHTSISPAKEklLNSSSKFSPLLNNEPPQSLQ 376
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
71-332 5.76e-07

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 51.62  E-value: 5.76e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720365910  71 VLTQQNTPSKLSEQRVRAESSSPIQSQRSQASKTAfecSECGKAFSKSSTLKKHQKLHTEKLNPSQKSPMKEKRYKCREC 150
Cdd:COG5048   219 NLENSSSSLPLTTNSQLSPKSLLSQSPSSLSSSDS---SSSASESPRSSLPTASSQSSSPNESDSSSEKGFSLPIKSKQC 295

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720365910 151 GKAFHQSTHLIHHQR--VHTGE--KPYQC--KDCGKAFSVSSSLSYHQKIHTGEKPFEC--NVCGKAFIRNIH-----LS 217
Cdd:COG5048   296 NISFSRSSPLTRHLRsvNHSGEslKPFSCpySLCGKLFSRNDALKRHILLHTSISPAKEklLNSSSKFSPLLNneppqSL 375

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720365910 218 HHHRMHTGEKPFQC--NLCDKAFVCRAHLTKHQHIHSGKKPYKCNecgkafnqstsflqhqrihtgekpfeCNECGKAFR 295
Cdd:COG5048   376 QQYKDLKNDKKSETlsNSCIRNFKRDSNLSLHIITHLSFRPYNCK--------------------------NPPCSKSFN 429

                         250       260       270
                  ....*....|....*....|....*....|....*..
gi 1720365910 296 VNSSLTEHQRIHTGEKPYQCIECGKAFRDNSSFARHR 332
Cdd:COG5048   430 RHYNLIPHKKIHTNHAPLLCSILKSFRRDLDLSNHGK 466
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
76-443 8.26e-07

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 51.24  E-value: 8.26e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720365910  76 NTPSKLSEQRVRAESSSPIQSQRSQASKTAFECSECgKAFSKSSTLKKHQKLHTEKLNPSQKSPMKEKRYKCRECGKAFH 155
Cdd:COG5048    73 FSRPLELSRHLRTHHNNPSDLNSKSLPLSNSKASSS-SLSSSSSNSNDNNLLSSHSLPPSSRDPQLPDLLSISNLRNNPL 151

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720365910 156 QSTHLIHHQRVHTGEKPYQC--KDCGKAFSVSSSLSYHQKIHTGEKPFECNVCGKAFIRNIHLSHHHRMHTGEKPFQCNL 233
Cdd:COG5048   152 PGNNSSSVNTPQSNSLHPPLpaNSLSKDPSSNLSLLISSNVSTSIPSSSENSPLSSSYSIPSSSSDQNLENSSSSLPLTT 231

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720365910 234 CdkAFVCRAHLTKHQHIhSGKKPYKCNECGKAFNQSTSFLQHQRIH----------TGEKPFECNECGKAFRVNSSLTEH 303
Cdd:COG5048   232 N--SQLSPKSLLSQSPS-SLSSSDSSSSASESPRSSLPTASSQSSSpnesdsssekGFSLPIKSKQCNISFSRSSPLTRH 308

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720365910 304 QR--IHTGE--KPYQCIE--CGKAFRDNSSFARHRKIHTGEKPYRCGLC-------EKAFRDQSALAQHQRTHTGEKPYT 370
Cdd:COG5048   309 LRsvNHSGEslKPFSCPYslCGKLFSRNDALKRHILLHTSISPAKEKLLnssskfsPLLNNEPPQSLQQYKDLKNDKKSE 388

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1720365910 371 C--NICEKAFSDHSALTQHKRIHTREKP--YKCKTCGKAFIRSTHLIQHQRIHTGEKPYKCNTCGKaFNQTANLAQH 443
Cdd:COG5048   389 TlsNSCIRNFKRDSNLSLHIITHLSFRPynCKNPPCSKSFNRHYNLIPHKKIHTNHAPLLCSILKS-FRRDLDLSNH 464
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
96-448 1.66e-05

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 47.00  E-value: 1.66e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720365910  96 SQRSQASKTAFECS--ECGKAFSKSSTLKKHQKLHTEK---LNPSQKSPMKEKRYKCRECGKAFHQSTHLIHHQRVHTGE 170
Cdd:COG5048    52 HIRSHTGEKPSQCSysGCDKSFSRPLELSRHLRTHHNNpsdLNSKSLPLSNSKASSSSLSSSSSNSNDNNLLSSHSLPPS 131

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720365910 171 KPYQCKDCGKAFSVSSSLSYHQKIHTG-------EKPFECNVCGKAFIRNIHLSH--HHRMHTGEKPFQCNLCDKAFVCR 241
Cdd:COG5048   132 SRDPQLPDLLSISNLRNNPLPGNNSSSvntpqsnSLHPPLPANSLSKDPSSNLSLliSSNVSTSIPSSSENSPLSSSYSI 211

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720365910 242 AHLTKHQHIHSGKKPYKCNECGKAFNQSTSFLQHQRIHTGEKPFECNECGKAFR--VNSSLTEHQRIHTGE-----KPYQ 314
Cdd:COG5048   212 PSSSSDQNLENSSSSLPLTTNSQLSPKSLLSQSPSSLSSSDSSSSASESPRSSLptASSQSSSPNESDSSSekgfsLPIK 291

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720365910 315 CIECGKAFRDNSSFARHR--KIHTGE--KPYRCG--LCEKAFRDQSALAQHQRTHTGEKPYTCNIC-------EKAFSDH 381
Cdd:COG5048   292 SKQCNISFSRSSPLTRHLrsVNHSGEslKPFSCPysLCGKLFSRNDALKRHILLHTSISPAKEKLLnssskfsPLLNNEP 371

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1720365910 382 SALTQHKRIHTREKPY------KCKTCGKAFIRSTHLIQH--QRIHtgekPYKCNTCGKAFNQTANLAQHQRHHT 448
Cdd:COG5048   372 PQSLQQYKDLKNDKKSetlsnsCIRNFKRDSNLSLHIITHlsFRPY----NCKNPPCSKSFNRHYNLIPHKKIHT 442
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 365-448 1.20e-04

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 44.32  E-value: 1.20e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720365910 365 GEKPYTCNI--CEKAFSDHSALTQHkRIHTREKPYKCKTCGKafirsthlIQHQRIHTGEKPYKCNTCGKAFNQTANLAQ 442
Cdd:COG5189   346 DGKPYKCPVegCNKKYKNQNGLKYH-MLHGHQNQKLHENPSP--------EKMNIFSAKDKPYRCEVCDKRYKNLNGLKY 416


                  ....*.
gi 1720365910 443 HQRHHT 448
Cdd:COG5189   417 HRKHSH 422
zf-H2C2_2 pfam13465
Zinc-finger double domain;
411-436 3.18e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 37.74  E-value: 3.18e-04
                          10        20
                  ....*....|....*....|....*.
gi 1720365910 411 HLIQHQRIHTGEKPYKCNTCGKAFNQ 436
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
SUF4-like cd20908
N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), ...
 395-448 7.88e-04

N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana SUF4 (AtSUF4), and similar proteins; Oryza sativa SUPPRESSOR OF FRI 4 (OsSUF4) is a C2H2-type zinc finger transcription factor which interacts with the major H3K36 methyltransferase SDG725 to promote H3K36me3 (tri-methylation at H3K9) establishment. The transcription factor OsSUF4 recognizes a specific 7-bp DNA element (5'-CGGAAAT-3'), which is contained in the promoter regions of many genes throughout the rice genome. Through interaction with OsSUF4, SDG725 is recruited to the promoters of key florigen genes, RICE FLOWERING LOCUS T1 (RFT1) and Heading date 3a (Hd3a), for H3K36 deposition to promote gene activation and rice plant flowering. OsSUF4 target genes include a number of genes involved in many biological processes. Flowering plant Arabidopsis SUF4 binds to a 15bp DNA element (5'-CCAAATTTTAAGTTT-3') within the promoter of the floral repressor gene FLOWERING LOCUS C (FLC) and recruits the FRI-C transcription activator complex to the FLC promoter. Although the DNA-binding element and target genes of AtSUF4 are different from those of OsSUF4, AtSUF4 is known to interact with the Arabidopsis H3K36 methyltransferase SDG8 (also known as ASHH2/EFS/SET8), and the methylation deposition mechanism mediated by the SUF4 transcription factor and H3K36 methyltransferase may be conserved in Arabidopsis and rice. Proteins in this family have two conserved C2H2-type zinc finger motifs at the N-terminus (included in this model), and a large proline-rich domain at the C-terminus; for OsSUF4, it has been shown that the N-terminal zinc-finger domain is responsible for DNA binding, and that the C-terminal domain interacts with SDG725.


Pssm-ID: 411020 [Multi-domain]  Cd Length: 82  Bit Score: 38.31  E-value: 7.88e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1720365910 395 KPYkCKTCGKAFIRSTHLIQHQRIHTgekpYKCNTCGKAFNQTANLAQH--QRHHT 448
Cdd:cd20908     1 KPW-CYYCDREFDDEKILIQHQKAKH----FKCHICHKKLYTAGGLAVHclQVHKE 51
zf-H2C2_2 pfam13465
Zinc-finger double domain;
299-322 9.56e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 36.58  E-value: 9.56e-04
                          10        20
                  ....*....|....*....|....
gi 1720365910 299 SLTEHQRIHTGEKPYQCIECGKAF 322
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSF 24
zf-H2C2_2 pfam13465
Zinc-finger double domain;
383-408 1.40e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 35.81  E-value: 1.40e-03
                          10        20
                  ....*....|....*....|....*.
gi 1720365910 383 ALTQHKRIHTREKPYKCKTCGKAFIR 408
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
187-212 1.67e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 35.81  E-value: 1.67e-03
                          10        20
                  ....*....|....*....|....*.
gi 1720365910 187 SLSYHQKIHTGEKPFECNVCGKAFIR 212
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
355-379 1.98e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 35.42  E-value: 1.98e-03
                          10        20
                  ....*....|....*....|....*
gi 1720365910 355 ALAQHQRTHTGEKPYTCNICEKAFS 379
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFK 25
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
395-451 2.70e-03

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 40.06  E-value: 2.70e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1720365910 395 KPYKCKTCGKAFIRSTHLIQHQRIHTGEKPYKCN--TCGKAFNQTANLAQHQRHHTGGK 451
Cdd:COG5048    32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSysGCDKSFSRPLELSRHLRTHHNNP 90
zf-H2C2_2 pfam13465
Zinc-finger double domain;
274-294 3.02e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 35.04  E-value: 3.02e-03
                          10        20
                  ....*....|....*....|.
gi 1720365910 274 QHQRIHTGEKPFECNECGKAF 294
Cdd:pfam13465   4 RHMRTHTGEKPYKCPECGKSF 24
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 253-333 3.61e-03

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 39.70  E-value: 3.61e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720365910 253 GKKPYKCN--ECGKAFNQSTSfLQHQRIHtgekpfecNECGKAFRVNSSLTEHQRIHTGEKPYQCIECGKAFRDNSSFAR 330
Cdd:COG5189   346 DGKPYKCPveGCNKKYKNQNG-LKYHMLH--------GHQNQKLHENPSPEKMNIFSAKDKPYRCEVCDKRYKNLNGLKY 416


                  ...
gi 1720365910 331 HRK 333
Cdd:COG5189   417 HRK 419
zf-H2C2_2 pfam13465
Zinc-finger double domain;
243-268 4.30e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 34.65  E-value: 4.30e-03
                          10        20
                  ....*....|....*....|....*.
gi 1720365910 243 HLTKHQHIHSGKKPYKCNECGKAFNQ 268
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
PHA00733 PHA00733
hypothetical protein
 368-415 7.12e-03

hypothetical protein


Pssm-ID: 177301  Cd Length: 128  Bit Score: 36.78  E-value: 7.12e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 1720365910 368 PYTCNICEKAFSDHSALTQHKRIHTREKpyKCKTCGKAFIRSTHLIQH 415
Cdd:PHA00733   73 PYVCPLCLMPFSSSVSLKQHIRYTEHSK--VCPVCGKEFRNTDSTLDH 118
zf-H2C2_2 pfam13465
Zinc-finger double domain;
163-183 8.55e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 33.88  E-value: 8.55e-03
                          10        20
                  ....*....|....*....|.
gi 1720365910 163 HQRVHTGEKPYQCKDCGKAFS 183
Cdd:pfam13465   5 HMRTHTGEKPYKCPECGKSFK 25
zf-H2C2_2 pfam13465
Zinc-finger double domain;
219-240 8.63e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 33.88  E-value: 8.63e-03
                          10        20
                  ....*....|....*....|..
gi 1720365910 219 HHRMHTGEKPFQCNLCDKAFVC 240
Cdd:pfam13465   5 HMRTHTGEKPYKCPECGKSFKS 26
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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