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Conserved domains on  [gi|1720386946|ref|XP_030104946|]
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golgin subfamily B member 1 isoform X2 [Mus musculus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1824-2748 3.58e-20

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 98.98  E-value: 3.58e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1824 LDQLKGRIAELE-----MEKQKDR-ELSQALENEKNALLTQISAKDselklLEEEVTKRTTLNQQIQEelcrVTKLKETA 1897
Cdd:TIGR02168  188 LDRLEDILNELErqlksLERQAEKaERYKELKAELRELELALLVLR-----LEELREELEELQEELKE----AEEELEEL 258

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1898 EEEKDDLEErlmnQLAELNGSIGNYYQDVTDAQIKNEQLESEMRNLQRCVSELEEEKQQLVKEKTKVESEIRKeymekiq 1977
Cdd:TIGR02168  259 TAELQELEE----KLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEE------- 327

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1978 gaqkgpaNKSHAKELQELLREKQQEVKQLQKDCIRYLERISALEKTVKALEFVHTESQKDLDVTKGNLAQAVEHRKKAQA 2057
Cdd:TIGR02168  328 -------LESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNN 400

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2058 ELSSFKILLDDTQSEAARVLADNLKLKKELQSNKesiksqikqkdedlLRRLEQAEEKHRKEKKNMQEKLDALHREKAHV 2137
Cdd:TIGR02168  401 EIERLEARLERLEDRRERLQQEIEELLKKLEEAE--------------LKELQAELEELEEELEELQEELERLEEALEEL 466

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2138 EETLAEIQVSLTRKDQEMKELQGSLDStlaqlaafTKSMSSLQDDRDRVIDEAKKWERRFGDAIQTKEE--EVRLKEENC 2215
Cdd:TIGR02168  467 REELEEAEQALDAAERELAQLQARLDS--------LERLQENLEGFSEGVKALLKNQSGLSGILGVLSEliSVDEGYEAA 538

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2216 IALKDQLRQMAIHMEELKITVSRLEHDKEIWESKAqTELQHHQKAYDKLQEENKELTSQLEDARQLYHDSKNELTKLESE 2295
Cdd:TIGR02168  539 IEAALGGRLQAVVVENLNAAKKAIAFLKQNELGRV-TFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKA 617

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2296 LKSLKDQ---TTDLNNSLEKCKehENNLEGIIKQQEADIQNCKFsceqletdlaasreltsrlhdeinakeqkIISLLSG 2372
Cdd:TIGR02168  618 LSYLLGGvlvVDDLDNALELAK--KLRPGYRIVTLDGDLVRPGG-----------------------------VITGGSA 666

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2373 KEEAIQLAVEelhqqhsKEIKELENLLSQEEEENVALEEENKRALEKTNQLTEALEAIKKESFEQKAQLDSFVKSMSSLq 2452
Cdd:TIGR02168  667 KTNSSILERR-------REIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARL- 738

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2453 ddrdrivsdyRQLEERHLSAILEKDQLIQDAAAENNKLKEEMRGLRSHMDDLNSENAKLDAELVQYRRDLNEVIAIKDSQ 2532
Cdd:TIGR02168  739 ----------EAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDEL 808

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2533 QKQLldaqlqqnKELRNECTKLEERLKGLEAEKQSLQMSSDALQKEKQGLSKEIKNLQTQLTALQEEGTlgVYHAQLKAK 2612
Cdd:TIGR02168  809 RAEL--------TLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIE--ELESELEAL 878

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2613 EEELQRLNMALSSSQKRTADLEEELvcvqKEATRKVSEIEDQ---LKKELKHLHHDAGIMRNETETAEERVAELARDLVE 2689
Cdd:TIGR02168  879 LNERASLEEALALLRSELEELSEEL----RELESKRSELRREleeLREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLE 954

                          890       900       910       920       930       940
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2690 M-EQKLLTVTKENKDLMAQIQAFGRSMSSLQDSRDHATEELGDLKKKYDASLKELAQLKE 2748
Cdd:TIGR02168  955 EaEALENKIEDDEEEARRRLKRLENKIKELGPVNLAAIEEYEELKERYDFLTAQKEDLTE 1014
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 215-1031 1.21e-19

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 97.43  E-value: 1.21e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  215 EQAAQVVREKDARFETQVRLHE-DELLQLVTqsDVETEMQQKLRVMQRKLEEHEEAllgRAQVVDLLQKELTSAEQRNQV 293
Cdd:TIGR02168  162 EEAAGISKYKERRKETERKLERtRENLDRLE--DILNELERQLKSLERQAEKAERY---KELKAELRELELALLVLRLEE 236

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  294 LSQQLQLLEAEhntlKNTMETERQESKTLMEKVELEVAERKLSFHNLQEEMHQLQGQLERAGQAQADLETQYSALQQRHK 373
Cdd:TIGR02168  237 LREELEELQEE----LKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLA 312

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  374 ---TEMEEKTACILSLQKNEQELQSACAALKEEN----------SKLLQEKHDQAAESAQAMRQLEDQLQQKSKEISQFV 440
Cdd:TIGR02168  313 nleRQLEELEAQLEELESKLDELAEELAELEEKLeelkeeleslEAELEELEAELEELESRLEELEEQLETLRSKVAQLE 392

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  441 NKPNLQKNEtasqtslpdvnnegdQAVMEETVASLQKRVVELENEKGALL---------LSSGELEELKAENEKLSSRit 511
Cdd:TIGR02168  393 LQIASLNNE---------------IERLEARLERLEDRRERLQQEIEELLkkleeaelkELQAELEELEEELEELQEE-- 455

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  512 LLEAQNRAGEADGTVCEVSTAGTTLLNRSDSSpeENGQAVLENTFsQKHKELSVLLVEMKEAQEEIAFLKSQL-QGKRPE 590
Cdd:TIGR02168  456 LERLEEALEELREELEEAEQALDAAERELAQL--QARLDSLERLQ-ENLEGFSEGVKALLKNQSGLSGILGVLsELISVD 532

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  591 GDYE--------------VLDRREVQLMESEGPPSVTAGDVLCAPSDESSGPAAEEEQAGMKDRHRaSEAGPLNDagMEL 656
Cdd:TIGR02168  533 EGYEaaieaalggrlqavVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIE-GFLGVAKD--LVK 609

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  657 SSPKLDGV-DKSLAVSHVCQCHQGELERLKTqvLELETSLHTAE------------ETYKRNLS--EKVKEISSLTQLSE 721
Cdd:TIGR02168  610 FDPKLRKAlSYLLGGVLVVDDLDNALELAKK--LRPGYRIVTLDgdlvrpggvitgGSAKTNSSilERRREIEELEEKIE 687

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  722 EVKESAEEARSTLAAVTEERDQLlyqvkeLDVLAELRARVQELESSLAEAEKqrglDYESQRAQHNLLTEQIHSLSIEAK 801
Cdd:TIGR02168  688 ELEEKIAELEKALAELRKELEEL------EEELEQLRKELEELSRQISALRK----DLARLEAEVEQLEERIAQLSKELT 757

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  802 SKDVKIEALQRELDGVQLQFCEQGTQMKTLQSQLEAKEREVREGTERLRDISQEMEGLSQALSQKELEIAKMDQLLLEKQ 881
Cdd:TIGR02168  758 ELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATE 837

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  882 KDVETLQQTIQEKDQQVTELSFSMTEKMVQLNEEKfslgveiKTLKEQLNLLSRTEEATKEQVEESGAgSSLKLGHDESG 961
Cdd:TIGR02168  838 RRLEDLEEQIEELSEDIESLAAEIEELEELIEELE-------SELEALLNERASLEEALALLRSELEE-LSEELRELESK 909

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1720386946  962 QEGLQQELELLRKESEQRKRKLQAALINRKELLQKVS---QLEEELAKVREDSRKEIPFG-ENERRKLEEDREN 1031
Cdd:TIGR02168  910 RSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSeeySLTLEEAEALENKIEDDEEEaRRRLKRLENKIKE 983
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 724-1629 6.77e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 91.66  E-value: 6.77e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  724 KESAEEARSTLAAVTEERDQLLyqvkelDVLAELRARVQELESSLAEAEKQRGLDYESQRAQHNLLTEQIHSLsieaksk 803
Cdd:TIGR02168  171 KERRKETERKLERTRENLDRLE------DILNELERQLKSLERQAEKAERYKELKAELRELELALLVLRLEEL------- 237

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  804 DVKIEALQRELDGVQLQFCEQGTQMKTLQSQLEAKEREVREGTERLRDISQEMEGLSQALSQKELEIAKMDQLLLEKQKD 883
Cdd:TIGR02168  238 REELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQ 317

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  884 VETLQQTIQEKDQQVTElsfsmtekmvqLNEEKFSLGVEIKTLKEQLNLLSRTEEATKEQVEESgagsslklghdESGQE 963
Cdd:TIGR02168  318 LEELEAQLEELESKLDE-----------LAEELAELEEKLEELKEELESLEAELEELEAELEEL-----------ESRLE 375

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  964 GLQQELELLRKESEQRKRKLQAALINRKELLQKVSQLEEELAkvredsrkeipfgenerRKLEEDRENRDDPEEWGTSKW 1043
Cdd:TIGR02168  376 ELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRE-----------------RLQQEIEELLKKLEEAELKEL 438

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1044 REVEASLKQTISEKEVELEGIRRDLKEKTAAEEELQAVVQRMTRDLQSKTKQIDLLqEEVTENQATIQKLVTGTMDAGNG 1123
Cdd:TIGR02168  439 QAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSL-ERLQENLEGFSEGVKALLKNQSG 517

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1124 GSA-APVKETAASSPPGaggeehWKPELE----GRILDLEKDKTQLQKKLQEALiarkailkKAQEKEKQLKEELREQKD 1198
Cdd:TIGR02168  518 LSGiLGVLSELISVDEG------YEAAIEaalgGRLQAVVVENLNAAKKAIAFL--------KQNELGRVTFLPLDSIKG 583

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1199 AyhHLQGQFHEQNKEKENIADQLRQLqcqarESIDRQLPGTGQqepgppaPSLEGISLEDTepaSESDLHAAQPSPPGET 1278
Cdd:TIGR02168  584 T--EIQGNDREILKNIEGFLGVAKDL-----VKFDPKLRKALS-------YLLGGVLVVDD---LDNALELAKKLRPGYR 646

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1279 AALQATVSVAQIQAQLKEMEVEKEELELKVssiaSELAKKSEEVLLLQDQINEQGLEIQNLKAASVEAQAHTELLKQELE 1358
Cdd:TIGR02168  647 IVTLDGDLVRPGGVITGGSAKTNSSILERR----REIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELE 722

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1359 SSQLKVAGL-EHLKTLQPELDALHKHMGQKEEEVNYLYGQLSEKEQTLTTVQTEMVEQERLIKalhtQLEMQAKEHEERL 1437
Cdd:TIGR02168  723 ELSRQISALrKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIE----ELEAQIEQLKEEL 798

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1438 KQAQVEICELKKKPTELEEE----TNAKQQLQRKLQAALISRKEALKENKSLQEQLSSARDAVERLTKSLADVESQVSVQ 1513
Cdd:TIGR02168  799 KALREALDELRAELTLLNEEaanlRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEAL 878

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1514 NQEKDAVLGKLTILQEERDKLIAEMDRFLLENQSLSGSCESLKLALGGLTEDKEKLMEELESVRSSKMAestewqekhkE 1593
Cdd:TIGR02168  879 LNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSE----------E 948

                          890       900       910
                   ....*....|....*....|....*....|....*.
gi 1720386946 1594 LQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQEL 1629
Cdd:TIGR02168  949 YSLTLEEAEALENKIEDDEEEARRRLKRLENKIKEL 984
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2413-3154 5.04e-10

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 65.85  E-value: 5.04e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2413 NKRALEKTNQLTEALEAIKKEsfEQKAQLDSFVKSMSSLQDDRDR---IVSDYRQLEERHLSAILEKDQLIQDAAAENNK 2489
Cdd:TIGR02168  201 QLKSLERQAEKAERYKELKAE--LRELELALLVLRLEELREELEElqeELKEAEEELEELTAELQELEEKLEELRLEVSE 278

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2490 LKEEMRGLRSHMDDLNSENAKLDAELVQYRRDLNEViaikdSQQKQLLDAQLQQNKELRNEctkLEERLKGLEAEKQSLQ 2569
Cdd:TIGR02168  279 LEEEIEELQKELYALANEISRLEQQKQILRERLANL-----ERQLEELEAQLEELESKLDE---LAEELAELEEKLEELK 350

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2570 MSSDALQKEKQGLSKEIKNLQTQLTALQEEgtlgvyHAQLKAKEEELQRlnmALSSSQKRTADLEEELVCVQKEATRKVS 2649
Cdd:TIGR02168  351 EELESLEAELEELEAELEELESRLEELEEQ------LETLRSKVAQLEL---QIASLNNEIERLEARLERLEDRRERLQQ 421

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2650 EIEDQLKKELKHLHHDAGIMRNETETAEErvaELARDLVEMEQKLLTVTKENKDLMAQIQAFGRSMSSLQdSRDHATEEL 2729
Cdd:TIGR02168  422 EIEELLKKLEEAELKELQAELEELEEELE---ELQEELERLEEALEELREELEEAEQALDAAERELAQLQ-ARLDSLERL 497

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2730 GDLKKKYDASLKELAQLKEWqdssregdvLSQAAFPLSTSENVLSRLEKLNQQLTSKDEQLLhLSSELESSHNQVQSISK 2809
Cdd:TIGR02168  498 QENLEGFSEGVKALLKNQSG---------LSGILGVLSELISVDEGYEAAIEAALGGRLQAV-VVENLNAAKKAIAFLKQ 567

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2810 AmtslqNERDRLWSELEKFRKSE-EGKQRAAAPSAASSPAEVQSLKKAMSSLQNDRDRLL------KELKNLQQQYLQMS 2882
Cdd:TIGR02168  568 N-----ELGRVTFLPLDSIKGTEiQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLggvlvvDDLDNALELAKKLR 642

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2883 QEMT-------------------------------ELRPLKAQLQESQDQTKALQVMEEELRQENLSWQHELRQLRMEKN 2931
Cdd:TIGR02168  643 PGYRivtldgdlvrpggvitggsaktnssilerrrEIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELE 722

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2932 SWELHERRMKEQfLMAISDKDQQLGHLQSLLRELRSSSQAQILSTQYQR-QASPETSASLDGSQKLVYETELLRTQLNDS 3010
Cdd:TIGR02168  723 ELSRQISALRKD-LARLEAEVEQLEERIAQLSKELTELEAEIEELEERLeEAEEELAEAEAEIEELEAQIEQLKEELKAL 801

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 3011 LKEIHQKELRIQQLNSKFSQLLEEKNVLSTQLSDASQSLRENQHHYSNLFNHCAILEKEVQKLQAGP--LNTDVapgapq 3088
Cdd:TIGR02168  802 REALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIeeLESEL------ 875

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1720386946 3089 EKNGMHRKSEPETTGEEQPSFSEVQQQLCNTKQDLRELKKLLEEERDQRLTAENALSLAKEQIRRL 3154
Cdd:TIGR02168  876 EALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNL 941
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 51-370 7.44e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 58.41  E-value: 7.44e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946   51 EDALHRLAEAEKLVVELKDIISQKDVQLqqkdEALQEEKKAAEN----KIKKIKLHAKAKIMSLNKHMEEIKTQGGAAlp 126
Cdd:COG1196    175 EEAERKLEATEENLERLEDILGELERQL----EPLERQAEKAERyrelKEELKELEAELLLLKLRELEAELEELEAEL-- 248

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  127 pEAQAEELSKHNKSSTEEEMEIEKIKHELQEKEKLISSLQAQLdqSEQASQLDKSSAEMEDFVLMKQQLQEKEELISTLQ 206
Cdd:COG1196    249 -EELEAELEELEAELAELEAELEELRLELEELELELEEAQAEE--YELLAELARLEQDIARLEERRRELEERLEELEEEL 325

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  207 TQLSQTQAEQAAQVVREKDARFETQVRLHEDElLQLVTQSDVETEMQQKLRVMQRKLEEHEEALLGRAQVVDLLQKELTS 286
Cdd:COG1196    326 AELEEELEELEEELEELEEELEEAEEELEEAE-AELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEE 404

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  287 AEQRNQVLSQQLQLLEAEHNTLkntmETERQESKTLMEKVELEVAERKLSFHNLQEEMHQLQGQLERAGQAQADLETQYS 366
Cdd:COG1196    405 LEEAEEALLERLERLEEELEEL----EEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALA 480


                   ....
gi 1720386946  367 ALQQ 370
Cdd:COG1196    481 ELLE 484
EnvC super family cl34844
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1704-1915 4.74e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG4942:

Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.53  E-value: 4.74e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1704 SSLKEELEKITLEHKTLSKEFEALMAEKDALSEETRNLKLQVEA--QVLKQASLEATEKSDEPKDVIEEVTQAVVGKSQE 1781
Cdd:COG4942     23 AEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAAlaRRIRALEQELAALEAELAELEKEIAELRAELEAQ 102

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1782 RDALSDSAKledsEAILMGDGAKPGV---SETFSSHDDIKNYLQQL-DQLKGRIAELEMEKQKDRELSQALENEKNALLT 1857
Cdd:COG4942    103 KEELAELLR----ALYRLGRQPPLALllsPEDFLDAVRRLQYLKYLaPARREQAEELRADLAELAALRAELEAERAELEA 178

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1720386946 1858 QISAKDSELKLLEEEVTKRTTLNQQIQEELcrvtKLKETAEEEKDDLEERLMNQLAEL 1915
Cdd:COG4942    179 LLAELEEERAALEALKAERQKLLARLEKEL----AELAAELAELQQEAEELEALIARL 232
 
Name Accession Description Interval E-value
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1824-2748 3.58e-20

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 98.98  E-value: 3.58e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1824 LDQLKGRIAELE-----MEKQKDR-ELSQALENEKNALLTQISAKDselklLEEEVTKRTTLNQQIQEelcrVTKLKETA 1897
Cdd:TIGR02168  188 LDRLEDILNELErqlksLERQAEKaERYKELKAELRELELALLVLR-----LEELREELEELQEELKE----AEEELEEL 258

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1898 EEEKDDLEErlmnQLAELNGSIGNYYQDVTDAQIKNEQLESEMRNLQRCVSELEEEKQQLVKEKTKVESEIRKeymekiq 1977
Cdd:TIGR02168  259 TAELQELEE----KLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEE------- 327

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1978 gaqkgpaNKSHAKELQELLREKQQEVKQLQKDCIRYLERISALEKTVKALEFVHTESQKDLDVTKGNLAQAVEHRKKAQA 2057
Cdd:TIGR02168  328 -------LESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNN 400

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2058 ELSSFKILLDDTQSEAARVLADNLKLKKELQSNKesiksqikqkdedlLRRLEQAEEKHRKEKKNMQEKLDALHREKAHV 2137
Cdd:TIGR02168  401 EIERLEARLERLEDRRERLQQEIEELLKKLEEAE--------------LKELQAELEELEEELEELQEELERLEEALEEL 466

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2138 EETLAEIQVSLTRKDQEMKELQGSLDStlaqlaafTKSMSSLQDDRDRVIDEAKKWERRFGDAIQTKEE--EVRLKEENC 2215
Cdd:TIGR02168  467 REELEEAEQALDAAERELAQLQARLDS--------LERLQENLEGFSEGVKALLKNQSGLSGILGVLSEliSVDEGYEAA 538

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2216 IALKDQLRQMAIHMEELKITVSRLEHDKEIWESKAqTELQHHQKAYDKLQEENKELTSQLEDARQLYHDSKNELTKLESE 2295
Cdd:TIGR02168  539 IEAALGGRLQAVVVENLNAAKKAIAFLKQNELGRV-TFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKA 617

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2296 LKSLKDQ---TTDLNNSLEKCKehENNLEGIIKQQEADIQNCKFsceqletdlaasreltsrlhdeinakeqkIISLLSG 2372
Cdd:TIGR02168  618 LSYLLGGvlvVDDLDNALELAK--KLRPGYRIVTLDGDLVRPGG-----------------------------VITGGSA 666

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2373 KEEAIQLAVEelhqqhsKEIKELENLLSQEEEENVALEEENKRALEKTNQLTEALEAIKKESFEQKAQLDSFVKSMSSLq 2452
Cdd:TIGR02168  667 KTNSSILERR-------REIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARL- 738

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2453 ddrdrivsdyRQLEERHLSAILEKDQLIQDAAAENNKLKEEMRGLRSHMDDLNSENAKLDAELVQYRRDLNEVIAIKDSQ 2532
Cdd:TIGR02168  739 ----------EAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDEL 808

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2533 QKQLldaqlqqnKELRNECTKLEERLKGLEAEKQSLQMSSDALQKEKQGLSKEIKNLQTQLTALQEEGTlgVYHAQLKAK 2612
Cdd:TIGR02168  809 RAEL--------TLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIE--ELESELEAL 878

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2613 EEELQRLNMALSSSQKRTADLEEELvcvqKEATRKVSEIEDQ---LKKELKHLHHDAGIMRNETETAEERVAELARDLVE 2689
Cdd:TIGR02168  879 LNERASLEEALALLRSELEELSEEL----RELESKRSELRREleeLREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLE 954

                          890       900       910       920       930       940
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2690 M-EQKLLTVTKENKDLMAQIQAFGRSMSSLQDSRDHATEELGDLKKKYDASLKELAQLKE 2748
Cdd:TIGR02168  955 EaEALENKIEDDEEEARRRLKRLENKIKELGPVNLAAIEEYEELKERYDFLTAQKEDLTE 1014
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 215-1031 1.21e-19

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 97.43  E-value: 1.21e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  215 EQAAQVVREKDARFETQVRLHE-DELLQLVTqsDVETEMQQKLRVMQRKLEEHEEAllgRAQVVDLLQKELTSAEQRNQV 293
Cdd:TIGR02168  162 EEAAGISKYKERRKETERKLERtRENLDRLE--DILNELERQLKSLERQAEKAERY---KELKAELRELELALLVLRLEE 236

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  294 LSQQLQLLEAEhntlKNTMETERQESKTLMEKVELEVAERKLSFHNLQEEMHQLQGQLERAGQAQADLETQYSALQQRHK 373
Cdd:TIGR02168  237 LREELEELQEE----LKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLA 312

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  374 ---TEMEEKTACILSLQKNEQELQSACAALKEEN----------SKLLQEKHDQAAESAQAMRQLEDQLQQKSKEISQFV 440
Cdd:TIGR02168  313 nleRQLEELEAQLEELESKLDELAEELAELEEKLeelkeeleslEAELEELEAELEELESRLEELEEQLETLRSKVAQLE 392

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  441 NKPNLQKNEtasqtslpdvnnegdQAVMEETVASLQKRVVELENEKGALL---------LSSGELEELKAENEKLSSRit 511
Cdd:TIGR02168  393 LQIASLNNE---------------IERLEARLERLEDRRERLQQEIEELLkkleeaelkELQAELEELEEELEELQEE-- 455

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  512 LLEAQNRAGEADGTVCEVSTAGTTLLNRSDSSpeENGQAVLENTFsQKHKELSVLLVEMKEAQEEIAFLKSQL-QGKRPE 590
Cdd:TIGR02168  456 LERLEEALEELREELEEAEQALDAAERELAQL--QARLDSLERLQ-ENLEGFSEGVKALLKNQSGLSGILGVLsELISVD 532

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  591 GDYE--------------VLDRREVQLMESEGPPSVTAGDVLCAPSDESSGPAAEEEQAGMKDRHRaSEAGPLNDagMEL 656
Cdd:TIGR02168  533 EGYEaaieaalggrlqavVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIE-GFLGVAKD--LVK 609

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  657 SSPKLDGV-DKSLAVSHVCQCHQGELERLKTqvLELETSLHTAE------------ETYKRNLS--EKVKEISSLTQLSE 721
Cdd:TIGR02168  610 FDPKLRKAlSYLLGGVLVVDDLDNALELAKK--LRPGYRIVTLDgdlvrpggvitgGSAKTNSSilERRREIEELEEKIE 687

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  722 EVKESAEEARSTLAAVTEERDQLlyqvkeLDVLAELRARVQELESSLAEAEKqrglDYESQRAQHNLLTEQIHSLSIEAK 801
Cdd:TIGR02168  688 ELEEKIAELEKALAELRKELEEL------EEELEQLRKELEELSRQISALRK----DLARLEAEVEQLEERIAQLSKELT 757

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  802 SKDVKIEALQRELDGVQLQFCEQGTQMKTLQSQLEAKEREVREGTERLRDISQEMEGLSQALSQKELEIAKMDQLLLEKQ 881
Cdd:TIGR02168  758 ELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATE 837

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  882 KDVETLQQTIQEKDQQVTELSFSMTEKMVQLNEEKfslgveiKTLKEQLNLLSRTEEATKEQVEESGAgSSLKLGHDESG 961
Cdd:TIGR02168  838 RRLEDLEEQIEELSEDIESLAAEIEELEELIEELE-------SELEALLNERASLEEALALLRSELEE-LSEELRELESK 909

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1720386946  962 QEGLQQELELLRKESEQRKRKLQAALINRKELLQKVS---QLEEELAKVREDSRKEIPFG-ENERRKLEEDREN 1031
Cdd:TIGR02168  910 RSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSeeySLTLEEAEALENKIEDDEEEaRRRLKRLENKIKE 983
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 724-1629 6.77e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 91.66  E-value: 6.77e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  724 KESAEEARSTLAAVTEERDQLLyqvkelDVLAELRARVQELESSLAEAEKQRGLDYESQRAQHNLLTEQIHSLsieaksk 803
Cdd:TIGR02168  171 KERRKETERKLERTRENLDRLE------DILNELERQLKSLERQAEKAERYKELKAELRELELALLVLRLEEL------- 237

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  804 DVKIEALQRELDGVQLQFCEQGTQMKTLQSQLEAKEREVREGTERLRDISQEMEGLSQALSQKELEIAKMDQLLLEKQKD 883
Cdd:TIGR02168  238 REELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQ 317

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  884 VETLQQTIQEKDQQVTElsfsmtekmvqLNEEKFSLGVEIKTLKEQLNLLSRTEEATKEQVEESgagsslklghdESGQE 963
Cdd:TIGR02168  318 LEELEAQLEELESKLDE-----------LAEELAELEEKLEELKEELESLEAELEELEAELEEL-----------ESRLE 375

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  964 GLQQELELLRKESEQRKRKLQAALINRKELLQKVSQLEEELAkvredsrkeipfgenerRKLEEDRENRDDPEEWGTSKW 1043
Cdd:TIGR02168  376 ELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRE-----------------RLQQEIEELLKKLEEAELKEL 438

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1044 REVEASLKQTISEKEVELEGIRRDLKEKTAAEEELQAVVQRMTRDLQSKTKQIDLLqEEVTENQATIQKLVTGTMDAGNG 1123
Cdd:TIGR02168  439 QAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSL-ERLQENLEGFSEGVKALLKNQSG 517

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1124 GSA-APVKETAASSPPGaggeehWKPELE----GRILDLEKDKTQLQKKLQEALiarkailkKAQEKEKQLKEELREQKD 1198
Cdd:TIGR02168  518 LSGiLGVLSELISVDEG------YEAAIEaalgGRLQAVVVENLNAAKKAIAFL--------KQNELGRVTFLPLDSIKG 583

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1199 AyhHLQGQFHEQNKEKENIADQLRQLqcqarESIDRQLPGTGQqepgppaPSLEGISLEDTepaSESDLHAAQPSPPGET 1278
Cdd:TIGR02168  584 T--EIQGNDREILKNIEGFLGVAKDL-----VKFDPKLRKALS-------YLLGGVLVVDD---LDNALELAKKLRPGYR 646

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1279 AALQATVSVAQIQAQLKEMEVEKEELELKVssiaSELAKKSEEVLLLQDQINEQGLEIQNLKAASVEAQAHTELLKQELE 1358
Cdd:TIGR02168  647 IVTLDGDLVRPGGVITGGSAKTNSSILERR----REIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELE 722

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1359 SSQLKVAGL-EHLKTLQPELDALHKHMGQKEEEVNYLYGQLSEKEQTLTTVQTEMVEQERLIKalhtQLEMQAKEHEERL 1437
Cdd:TIGR02168  723 ELSRQISALrKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIE----ELEAQIEQLKEEL 798

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1438 KQAQVEICELKKKPTELEEE----TNAKQQLQRKLQAALISRKEALKENKSLQEQLSSARDAVERLTKSLADVESQVSVQ 1513
Cdd:TIGR02168  799 KALREALDELRAELTLLNEEaanlRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEAL 878

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1514 NQEKDAVLGKLTILQEERDKLIAEMDRFLLENQSLSGSCESLKLALGGLTEDKEKLMEELESVRSSKMAestewqekhkE 1593
Cdd:TIGR02168  879 LNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSE----------E 948

                          890       900       910
                   ....*....|....*....|....*....|....*.
gi 1720386946 1594 LQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQEL 1629
Cdd:TIGR02168  949 YSLTLEEAEALENKIEDDEEEARRRLKRLENKIKEL 984
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 752-1394 6.13e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 78.44  E-value: 6.13e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  752 DVLAELRARVQELESSLAEAEKQRGLDYESQRAQHNLLTEQIHSLSIEAKSKDVKIEALQRELdgvqlqfceqgtqmKTL 831
Cdd:COG1196    193 DILGELERQLEPLERQAEKAERYRELKEELKELEAELLLLKLRELEAELEELEAELEELEAEL--------------EEL 258

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  832 QSQLEAKEREVREGTERLRDISQEMEGLSQALSQKELEIAKMDQLLLEKQKDVETLQQTIQEKDQQVTELsfsmTEKMVQ 911
Cdd:COG1196    259 EAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAEL----EEELEE 334

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  912 LNEEKFSLGVEIKTLKEQLNLLSRTEEATKEQVEEsgagsslklghDESGQEGLQQELELLRKESEQRKRKLQAALINRK 991
Cdd:COG1196    335 LEEELEELEEELEEAEEELEEAEAELAEAEEALLE-----------AEAELAEAEEELEELAEELLEALRAAAELAAQLE 403

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  992 ELLQKVSQLEEELAKVREDSRKEipfgENERRKLEEDRENRddpeewgtskwREVEASLKQTISEKEVELEGIRRDLKEK 1071
Cdd:COG1196    404 ELEEAEEALLERLERLEEELEEL----EEALAELEEEEEEE-----------EEALEEAAEEEAELEEEEEALLELLAEL 468

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1072 TAAEEELQAVVQRMTRDLQSKTKQIDLLQEEVTEnqatiqklvtgtMDAGNGGSAAPVKETAASSPPGAGGEEHWKPELE 1151
Cdd:COG1196    469 LEEAALLEAALAELLEELAEAAARLLLLLEAEAD------------YEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAY 536

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1152 GRILDLEKDKTQLQKKLQEALIARKAILKKAQEKEKQLKEELREQKDAYHHLQGQFHEQNKEKENIADQLRQLQCQARES 1231
Cdd:COG1196    537 EAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYY 616

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1232 IDRQLPGTGQQEPGPPAPSLEGISLEDTEPASESDLHAAQPSPPGETAALQATVSVAQIQAQLKEMEVEKEELELKVSSI 1311
Cdd:COG1196    617 VLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELE 696

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1312 ASELAKKSEEVLLLQDQINEQGLEIQNLKAASVEAQAHTELLKQELESSQLKVAGLEHLKTLQPELDALHKHMGQKEEEV 1391
Cdd:COG1196    697 EALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREI 776


                   ...
gi 1720386946 1392 NYL 1394
Cdd:COG1196    777 EAL 779
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1397-1970 9.36e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 78.05  E-value: 9.36e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1397 QLSEKEQTLTTVQTEMVEQERLIKALHTQLEMQAKEHEERLKQAQVEICELKKKPTELEE----ETNAKQQLQRKLQAAL 1472
Cdd:COG1196    243 ELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQdiarLEERRRELEERLEELE 322

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1473 ISRKEALKENKSLQEQLSSARDAVERLTKSLADVESQVSVQNQEKDAVLGKLTILQEERDKLIAEMDRFLLENQSLSGSC 1552
Cdd:COG1196    323 EELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQL 402

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1553 ESLKLALGGLTEDKEKLMEELESVRSSKMAESTEWQEKHKELQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQELYAK 1632
Cdd:COG1196    403 EELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAEL 482

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1633 LRSTESDKREREKQLQDAEQEMEEMKEKMRKFAKSKQQKILEL--EEENDRLRAEAQPVGGTGESMEALLSSNSSLKEEL 1710
Cdd:COG1196    483 LEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAvaVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAA 562

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1711 EKITLEHKTLSKEFEAL-MAEKDALSEETRNLKLQVEAQVLKQASLEATEKSDEPKDVIEEVTQAVVGKSQERDALSDSA 1789
Cdd:COG1196    563 IEYLKAAKAGRATFLPLdKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTL 642

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1790 KLEDSEAILMGDGAKPGVSETfsshddiknylqqLDQLKGRIAELEMEKQKDRELSQALENEKNALLTQISAKDSELKLL 1869
Cdd:COG1196    643 AGRLREVTLEGEGGSAGGSLT-------------GGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEEREL 709

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1870 EEEVTKRTTLNQQIQEELCRVTKLKETAEEEKDDLEERLMNQLAELNGSIgnyyQDVTDAQIKNEQLESEMRNLQRcV-- 1947
Cdd:COG1196    710 AEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEP----PDLEELERELERLEREIEALGP-Vnl 784

                          570       580
                   ....*....|....*....|....*....
gi 1720386946 1948 ------SELEEEKQQLVKEKTKVESEIRK 1970
Cdd:COG1196    785 laieeyEELEERYDFLSEQREDLEEARET 813
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 678-1252 1.20e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 74.20  E-value: 1.20e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  678 QGELERLKTQVLELETSLHTAEETYKRNLSEKVKEISSLTQLSEEVKESAEEARSTLAAVTEERDQLLYQVKELDVLAEL 757
Cdd:COG1196    238 EAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEER 317

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  758 RARVQELESSLAEAEKQRGLDYESQRAQHNLLTEQIHSLSIEAKSKDVKIEALQRELDGVQLQFCEQGTQMKTLQSQLEA 837
Cdd:COG1196    318 LEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAE 397

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  838 KEREVREGTERLRDISQEMEGLSQALSQKELEIAKMDQLLLEKQKDVETLQQTIQEKDQQVTELsfsmTEKMVQLNEEKF 917
Cdd:COG1196    398 LAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEAL----LELLAELLEEAA 473

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  918 SLGVEIKTLKEQLNLLSRTEEATKE-QVEESGAGSSLKLGHDESGQEGLQQELELLRKESEQRKRKLQAALInrkELLQK 996
Cdd:COG1196    474 LLEAALAELLEELAEAAARLLLLLEaEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALA---AALQN 550

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  997 VSQLEEELAKVREDSRKEIPFGENERRKLEEDRENRDDPeewgtskwrevEASLKQTISEKEVELEGIRRDLKEKTAAEE 1076
Cdd:COG1196    551 IVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALA-----------AALARGAIGAAVDLVASDLREADARYYVLG 619

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1077 ELQAVVQRMTRDLQSKTKQIDLLQEEVTEnqatiqklVTGTMDAGNGGSAapvketaassppgaggeehwkpelEGRILD 1156
Cdd:COG1196    620 DTLLGRTLVAARLEAALRRAVTLAGRLRE--------VTLEGEGGSAGGS------------------------LTGGSR 667

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1157 LEKDKTQLQKKLQEALIARKAILKKAQEKEKQLKEELREQKDAYHHLQGQFHEQNKEKENIADQLRQLQCQARESIDRQL 1236
Cdd:COG1196    668 RELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEEL 747

                          570
                   ....*....|....*.
gi 1720386946 1237 PGTGQQEPGPPAPSLE 1252
Cdd:COG1196    748 LEEEALEELPEPPDLE 763
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2413-3154 5.04e-10

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 65.85  E-value: 5.04e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2413 NKRALEKTNQLTEALEAIKKEsfEQKAQLDSFVKSMSSLQDDRDR---IVSDYRQLEERHLSAILEKDQLIQDAAAENNK 2489
Cdd:TIGR02168  201 QLKSLERQAEKAERYKELKAE--LRELELALLVLRLEELREELEElqeELKEAEEELEELTAELQELEEKLEELRLEVSE 278

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2490 LKEEMRGLRSHMDDLNSENAKLDAELVQYRRDLNEViaikdSQQKQLLDAQLQQNKELRNEctkLEERLKGLEAEKQSLQ 2569
Cdd:TIGR02168  279 LEEEIEELQKELYALANEISRLEQQKQILRERLANL-----ERQLEELEAQLEELESKLDE---LAEELAELEEKLEELK 350

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2570 MSSDALQKEKQGLSKEIKNLQTQLTALQEEgtlgvyHAQLKAKEEELQRlnmALSSSQKRTADLEEELVCVQKEATRKVS 2649
Cdd:TIGR02168  351 EELESLEAELEELEAELEELESRLEELEEQ------LETLRSKVAQLEL---QIASLNNEIERLEARLERLEDRRERLQQ 421

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2650 EIEDQLKKELKHLHHDAGIMRNETETAEErvaELARDLVEMEQKLLTVTKENKDLMAQIQAFGRSMSSLQdSRDHATEEL 2729
Cdd:TIGR02168  422 EIEELLKKLEEAELKELQAELEELEEELE---ELQEELERLEEALEELREELEEAEQALDAAERELAQLQ-ARLDSLERL 497

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2730 GDLKKKYDASLKELAQLKEWqdssregdvLSQAAFPLSTSENVLSRLEKLNQQLTSKDEQLLhLSSELESSHNQVQSISK 2809
Cdd:TIGR02168  498 QENLEGFSEGVKALLKNQSG---------LSGILGVLSELISVDEGYEAAIEAALGGRLQAV-VVENLNAAKKAIAFLKQ 567

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2810 AmtslqNERDRLWSELEKFRKSE-EGKQRAAAPSAASSPAEVQSLKKAMSSLQNDRDRLL------KELKNLQQQYLQMS 2882
Cdd:TIGR02168  568 N-----ELGRVTFLPLDSIKGTEiQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLggvlvvDDLDNALELAKKLR 642

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2883 QEMT-------------------------------ELRPLKAQLQESQDQTKALQVMEEELRQENLSWQHELRQLRMEKN 2931
Cdd:TIGR02168  643 PGYRivtldgdlvrpggvitggsaktnssilerrrEIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELE 722

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2932 SWELHERRMKEQfLMAISDKDQQLGHLQSLLRELRSSSQAQILSTQYQR-QASPETSASLDGSQKLVYETELLRTQLNDS 3010
Cdd:TIGR02168  723 ELSRQISALRKD-LARLEAEVEQLEERIAQLSKELTELEAEIEELEERLeEAEEELAEAEAEIEELEAQIEQLKEELKAL 801

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 3011 LKEIHQKELRIQQLNSKFSQLLEEKNVLSTQLSDASQSLRENQHHYSNLFNHCAILEKEVQKLQAGP--LNTDVapgapq 3088
Cdd:TIGR02168  802 REALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIeeLESEL------ 875

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1720386946 3089 EKNGMHRKSEPETTGEEQPSFSEVQQQLCNTKQDLRELKKLLEEERDQRLTAENALSLAKEQIRRL 3154
Cdd:TIGR02168  876 EALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNL 941
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1905-2475 1.98e-09

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 63.54  E-value: 1.98e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1905 EERLMNQLAELNGSIGNYYQDVTDAQIKNEQLESEMRNLQRCVSELEEEKQ---QLVKEKTKVESEIRKEyMEKIQGAQK 1981
Cdd:PRK03918   188 TENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEeieELEKELESLEGSKRKL-EEKIRELEE 266

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1982 GPANKshaKELQELLREKQQEVKQLQKDCIRYLERISALEKTVKALefvhtesqKDLDVTKGNLAQAVEHRKKAQAELSS 2061
Cdd:PRK03918   267 RIEEL---KKEIEELEEKVKELKELKEKAEEYIKLSEFYEEYLDEL--------REIEKRLSRLEEEINGIEERIKELEE 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2062 FKILLDDTQseaarvladnlKLKKELQSNKESIKSQIKQKDEdlLRRLEQAEEKHRKEKKN-----MQEKLDALHREKAH 2136
Cdd:PRK03918   336 KEERLEELK-----------KKLKELEKRLEELEERHELYEE--AKAKKEELERLKKRLTGltpekLEKELEELEKAKEE 402

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2137 VEETLAEIQVSLTRKDQEMKELQGSL-------------------DSTLAQLAAFTKSMSSLQDDRDRVIDEAKKWERRF 2197
Cdd:PRK03918   403 IEEEISKITARIGELKKEIKELKKAIeelkkakgkcpvcgrelteEHRKELLEEYTAELKRIEKELKEIEEKERKLRKEL 482

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2198 gdaiqTKEEEVRLKEENCIALKDQLRQMAIHMEELKitvsrlEHDKEIWESKAqTELQHHQKAYDKLQEENKELTSQLED 2277
Cdd:PRK03918   483 -----RELEKVLKKESELIKLKELAEQLKELEEKLK------KYNLEELEKKA-EEYEKLKEKLIKLKGEIKSLKKELEK 550

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2278 ARQLyhdsKNELTKLESELKSLKDQTTDLNNSLEKCK-EHENNLEGIIKQQEA------DIQNCKFSCEQLETDLAASRE 2350
Cdd:PRK03918   551 LEEL----KKKLAELEKKLDELEEELAELLKELEELGfESVEELEERLKELEPfyneylELKDAEKELEREEKELKKLEE 626

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2351 LTSRLHDEINAKEQKIISLLSGKEEAIQLAVEELHQQHSKEIKELENLLSQEEEENVALEEENKRALEKTNQLTEALEAI 2430
Cdd:PRK03918   627 ELDKAFEELAETEKRLEELRKELEELEKKYSEEEYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEER 706

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*
gi 1720386946 2431 KKesfeQKAQLDSFVKSMSSLQDDRDRIVSDYRQLEERHLSAILE 2475
Cdd:PRK03918   707 EK----AKKELEKLEKALERVEELREKVKKYKALLKERALSKVGE 747
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 728-1214 6.46e-09

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 62.16  E-value: 6.46e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  728 EEARSTLAAVTEERDQLLYQVKELDVLAELRARVQELESSLAEAEKQRGLDYESQ-RAQHNLLTEQIHSLSIEAKSKDVK 806
Cdd:pfam12128  237 MKIRPEFTKLQQEFNTLESAELRLSHLHFGYKSDETLIASRQEERQETSAELNQLlRTLDDQWKEKRDELNGELSAADAA 316

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  807 IEALQRELDGVQ---LQFCEQG--------TQMKTLQSQLEAKEREVREGTERLRDISQEMEGLSQALSQK-ELEIAKMD 874
Cdd:pfam12128  317 VAKDRSELEALEdqhGAFLDADietaaadqEQLPSWQSELENLEERLKALTGKHQDVTAKYNRRRSKIKEQnNRDIAGIK 396

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  875 QLLlEKQKDVETLQQTIQEKD--QQVTELSFSMTEKMVQLNEEKFSLGVEIKTLKEQLNLLSRTEE--ATKEQVEESGAG 950
Cdd:pfam12128  397 DKL-AKIREARDRQLAVAEDDlqALESELREQLEAGKLEFNEEEYRLKSRLGELKLRLNQATATPEllLQLENFDERIER 475

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  951 SSLKLGHDESGQEGLQQELELLRKESEQRKRKLQAALINRKELLQKVSQLEEEL----AKVREDSRKEIP-FGENERRKL 1025
Cdd:pfam12128  476 AREEQEAANAEVERLQSELRQARKRRDQASEALRQASRRLEERQSALDELELQLfpqaGTLLHFLRKEAPdWEQSIGKVI 555

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1026 EEDRENRDD--PEEWgtskwrevEASLKQTISEKEVELEGIRRDLKEKTAAEEELQAVVQRMTRDLQSKTKQIDLLQEEV 1103
Cdd:pfam12128  556 SPELLHRTDldPEVW--------DGSVGGELNLYGVKLDLKRIDVPEWAASEEELRERLDKAEEALQSAREKQAAAEEQL 627

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1104 TENQATIQKLVTGTMDAGNGGSAApvketaassppgaggeehwkpelEGRILDLEKDKTQLQKKLQEALIARKA-ILKKA 1182
Cdd:pfam12128  628 VQANGELEKASREETFARTALKNA-----------------------RLDLRRLFDEKQSEKDKKNKALAERKDsANERL 684

                          490       500       510
                   ....*....|....*....|....*....|..
gi 1720386946 1183 QEKEKQLKEELREQKDAYHHLQGQFHEQNKEK 1214
Cdd:pfam12128  685 NSLEAQLKQLDKKHQAWLEEQKEQKREARTEK 716
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 51-370 7.44e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 58.41  E-value: 7.44e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946   51 EDALHRLAEAEKLVVELKDIISQKDVQLqqkdEALQEEKKAAEN----KIKKIKLHAKAKIMSLNKHMEEIKTQGGAAlp 126
Cdd:COG1196    175 EEAERKLEATEENLERLEDILGELERQL----EPLERQAEKAERyrelKEELKELEAELLLLKLRELEAELEELEAEL-- 248

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  127 pEAQAEELSKHNKSSTEEEMEIEKIKHELQEKEKLISSLQAQLdqSEQASQLDKSSAEMEDFVLMKQQLQEKEELISTLQ 206
Cdd:COG1196    249 -EELEAELEELEAELAELEAELEELRLELEELELELEEAQAEE--YELLAELARLEQDIARLEERRRELEERLEELEEEL 325

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  207 TQLSQTQAEQAAQVVREKDARFETQVRLHEDElLQLVTQSDVETEMQQKLRVMQRKLEEHEEALLGRAQVVDLLQKELTS 286
Cdd:COG1196    326 AELEEELEELEEELEELEEELEEAEEELEEAE-AELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEE 404

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  287 AEQRNQVLSQQLQLLEAEHNTLkntmETERQESKTLMEKVELEVAERKLSFHNLQEEMHQLQGQLERAGQAQADLETQYS 366
Cdd:COG1196    405 LEEAEEALLERLERLEEELEEL----EEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALA 480


                   ....
gi 1720386946  367 ALQQ 370
Cdd:COG1196    481 ELLE 484
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1817-2588 1.25e-07

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 58.06  E-value: 1.25e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1817 IKNYLQQLDQLKGRIAELEMEKQKDRELSQALENEKNALLTQISAKDSELKLLEEEVTKRttlnQQIQEELCRVTKLKET 1896
Cdd:pfam02463  281 KKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEEL----EKELKELEIKREAEEE 356

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1897 AEEEKDDLEERLMNQLAELNGSIGNYYQDVTDAQIKNEQLESEMRNLQRCVS---ELEEEKQQLVKEKTKVESEIRKEYM 1973
Cdd:pfam02463  357 EEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQlllELARQLEDLLKEEKKEELEILEEEE 436

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1974 EKIQGAQKGPANKSHAKELQELLREKQQEVKQLQKDcirylerisalektvkalefvhtesqkdldvtKGNLAQAVEHRK 2053
Cdd:pfam02463  437 ESIELKQGKLTEEKEELEKQELKLLKDELELKKSED--------------------------------LLKETQLVKLQE 484

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2054 KAQAELSSFKILLDDTQSEAARVLADNLKLKKELQSNKESIKSQIKQKDEDLLRRLEQAEEKHRKEKKNMQEKLDALHRE 2133
Cdd:pfam02463  485 QLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQ 564

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2134 KAHVEETLAEIQVSLTRKDQEMKELQGSLDSTLAQLAAfTKSMSSLQDDRDRVIDEAKKWERRFGDAIQTKEEEVRLKEE 2213
Cdd:pfam02463  565 KLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPI-LNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKA 643

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2214 NCIALKDQLRQMAIHMEELKITVSRLEHDKEIWESKAQTELQHHQKAYDKLQEENKELTSQLEDARQLYHDSKNELTKLE 2293
Cdd:pfam02463  644 KESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELL 723

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2294 SELKSLKDQTTDLNNSLEKCKEHENNLEGIIKQQEADIQNCKFSCEQLETDLAASReltsRLHDEINAKEQKIISLLSGK 2373
Cdd:pfam02463  724 ADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEE----REKTEKLKVEEEKEEKLKAQ 799

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2374 EEAIQLAVEELHQQHSKEIKELENLLSQEEEENVALEEENKRALEKTNQLTEALEAIKKESFEQKAQLDSFVKSMSSLQD 2453
Cdd:pfam02463  800 EEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEEL 879

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2454 DRDRIVsDYRQLEERHLSAILEKDQLIQDAAAENNKLKEEMRGLRSHMDDLNSENAKLDAELVQYRRDLNEVIAIKDSQQ 2533
Cdd:pfam02463  880 EEQKLK-DELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEE 958

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1720386946 2534 KQLLDAQLQQNKELRN-------ECTKLEERLKGLEAEKQSLQMSSDALQKEKQGLSKEIKN 2588
Cdd:pfam02463  959 EERNKRLLLAKEELGKvnlmaieEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQRLK 1020
PTZ00121 PTZ00121
MAEBL; Provisional
 959-1687 2.91e-07

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 56.69  E-value: 2.91e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  959 ESGQEGLQQELELLRKESEQRKRKLQAALINRKELLQKVSQLEEElAKVREDSRKEIPFGENERRKLEEDRENRDDPEEW 1038
Cdd:PTZ00121  1101 EEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEA-RKAEDAKRVEIARKAEDARKAEEARKAEDAKKAE 1179

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1039 GTSKWREVEASLKQTISEKEVELEGIRRDLKEKTAAE---EELQAVVQRMTRDLQSKTKQIDLLQEEVTENQATIQKLVT 1115
Cdd:PTZ00121  1180 AARKAEEVRKAEELRKAEDARKAEAARKAEEERKAEEarkAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEE 1259

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1116 GTMDAGNGGSAAPVKETAASSPPGAGGEEHWKPElEGRILDLEKDKTQLQKKLQEALIARKAiLKKAQEKEKQ---LKEE 1192
Cdd:PTZ00121  1260 ARMAHFARRQAAIKAEEARKADELKKAEEKKKAD-EAKKAEEKKKADEAKKKAEEAKKADEA-KKKAEEAKKKadaAKKK 1337

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1193 LREQKDAYHHLQGQFHEQNKEKENIADQLRQLQCQARESIDRQLPGTGQQEPGPPAPSLEGISLEDTEPASESDLHAAQP 1272
Cdd:PTZ00121  1338 AEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAK 1417

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1273 SPPGETAALQATVSVAQiqaqlkemeveKEELELKVSSIASELAKKSEEvlllqdqineqGLEIQNLKAASVEAQAHTEL 1352
Cdd:PTZ00121  1418 KKADEAKKKAEEKKKAD-----------EAKKKAEEAKKADEAKKKAEE-----------AKKAEEAKKKAEEAKKADEA 1475

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1353 LKQELESSQlkvagLEHLKTLQPELDALHKHMGQKEEEVNYLyGQLSEKEQTLTTVQTEMVEQERliKALHTQLEMQAKE 1432
Cdd:PTZ00121  1476 KKKAEEAKK-----ADEAKKKAEEAKKKADEAKKAAEAKKKA-DEAKKAEEAKKADEAKKAEEAK--KADEAKKAEEKKK 1547

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1433 HEERLKQAQVEICELKKKPTELEEETNAKQQLQRKLQAALISRKEALKENKSLQEQLSSARDAVERLTKSLADVESQVSV 1512
Cdd:PTZ00121  1548 ADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKK 1627

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1513 QNQEKDAVLGKLTILQEERDKliAEMDRFLLENQSLSGSCESLKLALGGLTEDKEKLMEELESVRSSKMAESTEWQEKHK 1592
Cdd:PTZ00121  1628 AEEEKKKVEQLKKKEAEEKKK--AEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAE 1705

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1593 ELQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQELYAKLRSTESDKREREKQLQDAEQEMEEMKEKMRKFAKSKQQki 1672
Cdd:PTZ00121  1706 ELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEE-- 1783

                          730
                   ....*....|....*
gi 1720386946 1673 lELEEENDRLRAEAQ 1687
Cdd:PTZ00121  1784 -ELDEEDEKRRMEVD 1797
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1325-1767 1.40e-06

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 54.35  E-value: 1.40e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1325 LQDQINEQGLEIQNL----KAASVEAQAHTEllkQELESSQLKVAGLEHLKTLQPELDALHKHMGQKEEEVNYLYGQLSE 1400
Cdd:pfam15921  417 LRRELDDRNMEVQRLeallKAMKSECQGQME---RQMAAIQGKNESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLES 493

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1401 KEQTLTTVQTEMVEQERLIKALHTQLEMQAKEHEERLKQAQveicelkkkptELEEETNAKQQLQRKLQAALISRKEALK 1480
Cdd:pfam15921  494 SERTVSDLTASLQEKERAIEATNAEITKLRSRVDLKLQELQ-----------HLKNEGDHLRNVQTECEALKLQMAEKDK 562

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1481 ENKSLQEQLSSARDAV---ERLTKSLADVESQVSVQNQEKDAVLGKLTILQEERDKLIAEmdrflLENQSLSGSCESLKL 1557
Cdd:pfam15921  563 VIEILRQQIENMTQLVgqhGRTAGAMQVEKAQLEKEINDRRLELQEFKILKDKKDAKIRE-----LEARVSDLELEKVKL 637

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1558 ALGGltEDKEKLMEELESVRSSKMAESTEWQEKHKELQKEYEVLLQSYENVSNEAERIQHvvesvrqekqELYAKLRSTE 1637
Cdd:pfam15921  638 VNAG--SERLRAVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMETTTN----------KLKMQLKSAQ 705

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1638 SDKREREKQLQDAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEAQPVGGTGESMEALLSSNSSLKEELEKITLEH 1717
Cdd:pfam15921  706 SELEQTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATEK 785

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1718 KTLSKEFEALMAEKDALSEETRNLKLQVEAQVLKQASLEATEKSDEPKDV 1767
Cdd:pfam15921  786 NKMAGELEVLRSQERRLKEKVANMEVALDKASLQFAECQDIIQRQEQESV 835
PTZ00121 PTZ00121
MAEBL; Provisional
 708-1223 6.66e-06

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 52.45  E-value: 6.66e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  708 EKVKEISSLTQLSEEVKESAEEARSTLAAVTEERDQLLYQVKELDVLAELRARVQELEsslaEAEKQRGLDyESQRAQHN 787
Cdd:PTZ00121  1227 EAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELK----KAEEKKKAD-EAKKAEEK 1301

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  788 LLTEQIHSLSIEAKSKD---VKIEALQRELDGVQLQFCEQGTQMKTLQSQLEAKEREVREGTERlrdisQEMEGLSQALS 864
Cdd:PTZ00121  1302 KKADEAKKKAEEAKKADeakKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEK-----AEAAEKKKEEA 1376

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  865 QKELEIAKMDQlllEKQKDVETLQQTIQEKDQQVTELSFSMTEKmvQLNEEKFSLGVEIKT---LKEQLNLLSRTEEATK 941
Cdd:PTZ00121  1377 KKKADAAKKKA---EEKKKADEAKKKAEEDKKKADELKKAAAAK--KKADEAKKKAEEKKKadeAKKKAEEAKKADEAKK 1451

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  942 EQVEESGAGSSLKLGHDESGQEGLQQELELLRKESEQRKRKLQAalinrKELLQKVSQLEEELAKVREDSRKEIPFGENE 1021
Cdd:PTZ00121  1452 KAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEA-----KKKADEAKKAAEAKKKADEAKKAEEAKKADE 1526

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1022 RRKLEEDRENRDDPEEWGTSKWREVEASlkqtiseKEVELEGIRRDLKEKTAAEEELQAVVQRMTRDLQSKTKQIDLLQE 1101
Cdd:PTZ00121  1527 AKKAEEAKKADEAKKAEEKKKADELKKA-------EELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMK 1599

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1102 EVTENQatiqklvtgTMDAGNGGSAAPVKETAASSPPGAggEEHWKPELEGRILDLEKDKTQLQKKLQEALIARKAILKK 1181
Cdd:PTZ00121  1600 LYEEEK---------KMKAEEAKKAEEAKIKAEELKKAE--EEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAK 1668

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|..
gi 1720386946 1182 AQEKEKQLKEELREQKDAYHHLQGQFHEQNKEKENiADQLRQ 1223
Cdd:PTZ00121  1669 KAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKK-AEELKK 1709
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2770-3048 1.67e-05

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 50.71  E-value: 1.67e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2770 ENVLSRLEKLNQQLTSKDEQLLHLSSELESSHNQVQSISKAMTSLQNERDRLWSELEKFRKSEEGKQRaaapsaasspaE 2849
Cdd:COG1196    235 RELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQ-----------D 303

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2850 VQSLKKAMSSLQNDRDRLLKELKNLQQQYLQMSQEMTELRPLKAQLQESQDQTKALQVMEEELRQENLSWQHELRQLRME 2929
Cdd:COG1196    304 IARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEE 383

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2930 KNSWELHERRMKEQFLMAISDKDQQLGHLQSLLRELRSSSQAQILSTQYQRQASPETSASLDGSQKLVYETELLRTQLND 3009
Cdd:COG1196    384 LAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLE 463

                          250       260       270
                   ....*....|....*....|....*....|....*....
gi 1720386946 3010 SLKEIHQKELRIQQLNSKFSQLLEEKNVLSTQLSDASQS 3048
Cdd:COG1196    464 LLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEAD 502
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 2471-3051 4.84e-05

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 49.45  E-value: 4.84e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2471 SAILEKDQLIQDAAAENNKLKEEMRGLRSHM----DDLNSENAKLDAELVQYRRDLNEViaikDSQQKQLLDAQLQQNK- 2545
Cdd:pfam12128  269 SDETLIASRQEERQETSAELNQLLRTLDDQWkekrDELNGELSAADAAVAKDRSELEAL----EDQHGAFLDADIETAAa 344

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2546 ------ELRNECTKLEERLKGLEAEKQSLQMSSDAL-QKEKQGLSKEIKNLQTQLTALQEEGTLG------VYHAQLKAK 2612
Cdd:pfam12128  345 dqeqlpSWQSELENLEERLKALTGKHQDVTAKYNRRrSKIKEQNNRDIAGIKDKLAKIREARDRQlavaedDLQALESEL 424

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2613 EEELQRLNMALSSSQKRTADLEEELVCVQKEATRKVSEIEDQLKK--ELKHLHHDAGIMRNETETA--EERVAELARD-- 2686
Cdd:pfam12128  425 REQLEAGKLEFNEEEYRLKSRLGELKLRLNQATATPELLLQLENFdeRIERAREEQEAANAEVERLqsELRQARKRRDqa 504

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2687 ---LVEMEQKLLTVTKENKDLMAQIqaFGRSMSSLQDSRDHATEELGDLKKKYDASLKELAQLKEWQDSSREGDVLSQAA 2763
Cdd:pfam12128  505 seaLRQASRRLEERQSALDELELQL--FPQAGTLLHFLRKEAPDWEQSIGKVISPELLHRTDLDPEVWDGSVGGELNLYG 582

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2764 FPLSTSENVLSRLEKLNQQLTSKDEQllhLSSELESSHNQVQSISKAMTSLQNERDRLWSELEkfrkseegkqraaapsa 2843
Cdd:pfam12128  583 VKLDLKRIDVPEWAASEEELRERLDK---AEEALQSAREKQAAAEEQLVQANGELEKASREET----------------- 642

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2844 asspaevqslkKAMSSLQNDRDRlLKELKNLQQQYLQMSQEMTELRPLKAQlQESQDQTKALQVMEEELRQENLSWQHEL 2923
Cdd:pfam12128  643 -----------FARTALKNARLD-LRRLFDEKQSEKDKKNKALAERKDSAN-ERLNSLEAQLKQLDKKHQAWLEEQKEQK 709

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2924 RQLRMEKNswelherrmkEQFLMAISDKDQQLGHLQSLLRELRSSSQAQI--LSTQYQRQAspetsASLDGSQKLVYETE 3001
Cdd:pfam12128  710 REARTEKQ----------AYWQVVEGALDAQLALLKAAIAARRSGAKAELkaLETWYKRDL-----ASLGVDPDVIAKLK 774

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1720386946 3002 LLRTQLNDSLKEIHQKELRIQQLNSKF-SQLLEEKNVLSTQLSDASQSLRE 3051
Cdd:pfam12128  775 REIRTLERKIERIAVRRQEVLRYFDWYqETWLQRRPRLATQLSNIERAISE 825
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1704-1915 4.74e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.53  E-value: 4.74e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1704 SSLKEELEKITLEHKTLSKEFEALMAEKDALSEETRNLKLQVEA--QVLKQASLEATEKSDEPKDVIEEVTQAVVGKSQE 1781
Cdd:COG4942     23 AEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAAlaRRIRALEQELAALEAELAELEKEIAELRAELEAQ 102

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1782 RDALSDSAKledsEAILMGDGAKPGV---SETFSSHDDIKNYLQQL-DQLKGRIAELEMEKQKDRELSQALENEKNALLT 1857
Cdd:COG4942    103 KEELAELLR----ALYRLGRQPPLALllsPEDFLDAVRRLQYLKYLaPARREQAEELRADLAELAALRAELEAERAELEA 178

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1720386946 1858 QISAKDSELKLLEEEVTKRTTLNQQIQEELcrvtKLKETAEEEKDDLEERLMNQLAEL 1915
Cdd:COG4942    179 LLAELEEERAALEALKAERQKLLARLEKEL----AELAAELAELQQEAEELEALIARL 232
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
2545-3030 2.98e-03

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 43.51  E-value: 2.98e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2545 KELRNECTKLEERLKGLEAEKQSLQMSSDALQKEKQGLSKEIKNLQTQLTALQEE-GTLGVYHAQLKAKEEELQRLNMAL 2623
Cdd:PRK03918   168 GEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREElEKLEKEVKELEELKEEIEELEKEL 247

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2624 SSSQKRTADLEEELVCVQKEATRKVSEIEDqLKKELKHLhhdagimrNETETAEERVAELARDLVEMEQKLLTVTKENKD 2703
Cdd:PRK03918   248 ESLEGSKRKLEEKIRELEERIEELKKEIEE-LEEKVKEL--------KELKEKAEEYIKLSEFYEEYLDELREIEKRLSR 318

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2704 LMAQIQAFGRSMSSLQDSRdhatEELGDLKKKYDASLKELAQLKEWQDSSREGDVLSQAAFPLSTSENVLSrLEKLNQQL 2783
Cdd:PRK03918   319 LEEEINGIEERIKELEEKE----ERLEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLT-PEKLEKEL 393

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2784 TSKDEQLLHLSSELESshnqvqsISKAMTSLQNERDRLWSELEKFRKSE--------EGKQRAAAPSAASSPAEVQSLKK 2855
Cdd:PRK03918   394 EELEKAKEEIEEEISK-------ITARIGELKKEIKELKKAIEELKKAKgkcpvcgrELTEEHRKELLEEYTAELKRIEK 466

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2856 AMSSLQNDRDRLLKELKNLQQQyLQMSQEMTELRPLKAQLQESQDQTKALQVME--------EELRQENLSWQHELRQLR 2927
Cdd:PRK03918   467 ELKEIEEKERKLRKELRELEKV-LKKESELIKLKELAEQLKELEEKLKKYNLEElekkaeeyEKLKEKLIKLKGEIKSLK 545

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2928 MEKNSWELHERRmKEQFLMAISDKDQQLGHLQSLLRELRSSSQAQI------LSTQYQR-----QASPETSASLDGSQKL 2996
Cdd:PRK03918   546 KELEKLEELKKK-LAELEKKLDELEEELAELLKELEELGFESVEELeerlkeLEPFYNEylelkDAEKELEREEKELKKL 624

                          490       500       510
                   ....*....|....*....|....*....|....
gi 1720386946 2997 VYETELLRTQLNDSLKEIHQKELRIQQLNSKFSQ 3030
Cdd:PRK03918   625 EEELDKAFEELAETEKRLEELRKELEELEKKYSE 658
 
Name Accession Description Interval E-value
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1824-2748 3.58e-20

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 98.98  E-value: 3.58e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1824 LDQLKGRIAELE-----MEKQKDR-ELSQALENEKNALLTQISAKDselklLEEEVTKRTTLNQQIQEelcrVTKLKETA 1897
Cdd:TIGR02168  188 LDRLEDILNELErqlksLERQAEKaERYKELKAELRELELALLVLR-----LEELREELEELQEELKE----AEEELEEL 258

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1898 EEEKDDLEErlmnQLAELNGSIGNYYQDVTDAQIKNEQLESEMRNLQRCVSELEEEKQQLVKEKTKVESEIRKeymekiq 1977
Cdd:TIGR02168  259 TAELQELEE----KLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEE------- 327

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1978 gaqkgpaNKSHAKELQELLREKQQEVKQLQKDCIRYLERISALEKTVKALEFVHTESQKDLDVTKGNLAQAVEHRKKAQA 2057
Cdd:TIGR02168  328 -------LESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNN 400

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2058 ELSSFKILLDDTQSEAARVLADNLKLKKELQSNKesiksqikqkdedlLRRLEQAEEKHRKEKKNMQEKLDALHREKAHV 2137
Cdd:TIGR02168  401 EIERLEARLERLEDRRERLQQEIEELLKKLEEAE--------------LKELQAELEELEEELEELQEELERLEEALEEL 466

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2138 EETLAEIQVSLTRKDQEMKELQGSLDStlaqlaafTKSMSSLQDDRDRVIDEAKKWERRFGDAIQTKEE--EVRLKEENC 2215
Cdd:TIGR02168  467 REELEEAEQALDAAERELAQLQARLDS--------LERLQENLEGFSEGVKALLKNQSGLSGILGVLSEliSVDEGYEAA 538

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2216 IALKDQLRQMAIHMEELKITVSRLEHDKEIWESKAqTELQHHQKAYDKLQEENKELTSQLEDARQLYHDSKNELTKLESE 2295
Cdd:TIGR02168  539 IEAALGGRLQAVVVENLNAAKKAIAFLKQNELGRV-TFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKA 617

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2296 LKSLKDQ---TTDLNNSLEKCKehENNLEGIIKQQEADIQNCKFsceqletdlaasreltsrlhdeinakeqkIISLLSG 2372
Cdd:TIGR02168  618 LSYLLGGvlvVDDLDNALELAK--KLRPGYRIVTLDGDLVRPGG-----------------------------VITGGSA 666

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2373 KEEAIQLAVEelhqqhsKEIKELENLLSQEEEENVALEEENKRALEKTNQLTEALEAIKKESFEQKAQLDSFVKSMSSLq 2452
Cdd:TIGR02168  667 KTNSSILERR-------REIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARL- 738

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2453 ddrdrivsdyRQLEERHLSAILEKDQLIQDAAAENNKLKEEMRGLRSHMDDLNSENAKLDAELVQYRRDLNEVIAIKDSQ 2532
Cdd:TIGR02168  739 ----------EAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDEL 808

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2533 QKQLldaqlqqnKELRNECTKLEERLKGLEAEKQSLQMSSDALQKEKQGLSKEIKNLQTQLTALQEEGTlgVYHAQLKAK 2612
Cdd:TIGR02168  809 RAEL--------TLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIE--ELESELEAL 878

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2613 EEELQRLNMALSSSQKRTADLEEELvcvqKEATRKVSEIEDQ---LKKELKHLHHDAGIMRNETETAEERVAELARDLVE 2689
Cdd:TIGR02168  879 LNERASLEEALALLRSELEELSEEL----RELESKRSELRREleeLREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLE 954

                          890       900       910       920       930       940
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2690 M-EQKLLTVTKENKDLMAQIQAFGRSMSSLQDSRDHATEELGDLKKKYDASLKELAQLKE 2748
Cdd:TIGR02168  955 EaEALENKIEDDEEEARRRLKRLENKIKELGPVNLAAIEEYEELKERYDFLTAQKEDLTE 1014
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 215-1031 1.21e-19

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 97.43  E-value: 1.21e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  215 EQAAQVVREKDARFETQVRLHE-DELLQLVTqsDVETEMQQKLRVMQRKLEEHEEAllgRAQVVDLLQKELTSAEQRNQV 293
Cdd:TIGR02168  162 EEAAGISKYKERRKETERKLERtRENLDRLE--DILNELERQLKSLERQAEKAERY---KELKAELRELELALLVLRLEE 236

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  294 LSQQLQLLEAEhntlKNTMETERQESKTLMEKVELEVAERKLSFHNLQEEMHQLQGQLERAGQAQADLETQYSALQQRHK 373
Cdd:TIGR02168  237 LREELEELQEE----LKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLA 312

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  374 ---TEMEEKTACILSLQKNEQELQSACAALKEEN----------SKLLQEKHDQAAESAQAMRQLEDQLQQKSKEISQFV 440
Cdd:TIGR02168  313 nleRQLEELEAQLEELESKLDELAEELAELEEKLeelkeeleslEAELEELEAELEELESRLEELEEQLETLRSKVAQLE 392

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  441 NKPNLQKNEtasqtslpdvnnegdQAVMEETVASLQKRVVELENEKGALL---------LSSGELEELKAENEKLSSRit 511
Cdd:TIGR02168  393 LQIASLNNE---------------IERLEARLERLEDRRERLQQEIEELLkkleeaelkELQAELEELEEELEELQEE-- 455

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  512 LLEAQNRAGEADGTVCEVSTAGTTLLNRSDSSpeENGQAVLENTFsQKHKELSVLLVEMKEAQEEIAFLKSQL-QGKRPE 590
Cdd:TIGR02168  456 LERLEEALEELREELEEAEQALDAAERELAQL--QARLDSLERLQ-ENLEGFSEGVKALLKNQSGLSGILGVLsELISVD 532

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  591 GDYE--------------VLDRREVQLMESEGPPSVTAGDVLCAPSDESSGPAAEEEQAGMKDRHRaSEAGPLNDagMEL 656
Cdd:TIGR02168  533 EGYEaaieaalggrlqavVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIE-GFLGVAKD--LVK 609

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  657 SSPKLDGV-DKSLAVSHVCQCHQGELERLKTqvLELETSLHTAE------------ETYKRNLS--EKVKEISSLTQLSE 721
Cdd:TIGR02168  610 FDPKLRKAlSYLLGGVLVVDDLDNALELAKK--LRPGYRIVTLDgdlvrpggvitgGSAKTNSSilERRREIEELEEKIE 687

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  722 EVKESAEEARSTLAAVTEERDQLlyqvkeLDVLAELRARVQELESSLAEAEKqrglDYESQRAQHNLLTEQIHSLSIEAK 801
Cdd:TIGR02168  688 ELEEKIAELEKALAELRKELEEL------EEELEQLRKELEELSRQISALRK----DLARLEAEVEQLEERIAQLSKELT 757

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  802 SKDVKIEALQRELDGVQLQFCEQGTQMKTLQSQLEAKEREVREGTERLRDISQEMEGLSQALSQKELEIAKMDQLLLEKQ 881
Cdd:TIGR02168  758 ELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATE 837

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  882 KDVETLQQTIQEKDQQVTELSFSMTEKMVQLNEEKfslgveiKTLKEQLNLLSRTEEATKEQVEESGAgSSLKLGHDESG 961
Cdd:TIGR02168  838 RRLEDLEEQIEELSEDIESLAAEIEELEELIEELE-------SELEALLNERASLEEALALLRSELEE-LSEELRELESK 909

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1720386946  962 QEGLQQELELLRKESEQRKRKLQAALINRKELLQKVS---QLEEELAKVREDSRKEIPFG-ENERRKLEEDREN 1031
Cdd:TIGR02168  910 RSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSeeySLTLEEAEALENKIEDDEEEaRRRLKRLENKIKE 983
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2094-2906 3.41e-19

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 95.89  E-value: 3.41e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2094 IKSQIKQKDEDLL-RRLEQAEEKHR---KEKKNMQEKLDALHREKAHVEETLAEIQVSLTRKDQEMKELQGSLDSTLAQL 2169
Cdd:TIGR02168  218 LKAELRELELALLvLRLEELREELEelqEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEI 297

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2170 AAFTKSMSSLQDDRDRVIDEAKKWERRFGDAIQTKEEevrlKEENCIALKDQLRQMAIHMEELKITVSRLEHDKEIWESK 2249
Cdd:TIGR02168  298 SRLEQQKQILRERLANLERQLEELEAQLEELESKLDE----LAEELAELEEKLEELKEELESLEAELEELEAELEELESR 373

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2250 aqtelqhhqkaydklqeeNKELTSQLEDARQLYHDSKNELTKLESELKSLKDQTTDLNNSLEKckEHENNLEGIIKQQEA 2329
Cdd:TIGR02168  374 ------------------LEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRER--LQQEIEELLKKLEEA 433

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2330 DIQNCKFSCEQLETDLAasrELTSRLhDEINAKEQKIISLLSGKEEAIQLAVEELhQQHSKEIKELENLLSQEEEENVAL 2409
Cdd:TIGR02168  434 ELKELQAELEELEEELE---ELQEEL-ERLEEALEELREELEEAEQALDAAEREL-AQLQARLDSLERLQENLEGFSEGV 508

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2410 EEENKRALEKTNQLTEALEAIKKESFEQKAQLDSFVKSMSSLQDDRD----RIVSDYRQLEERHLSAILEKDQLIQDAAA 2485
Cdd:TIGR02168  509 KALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGRLQAVVVENLnaakKAIAFLKQNELGRVTFLPLDSIKGTEIQG 588

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2486 ENNKLKEEMRGLRSHMDDLNSENAKLDAeLVQYRrdLNEVIAIKDsqqkqlLDAQLQQNKELRnectkLEERLKGLEAE- 2564
Cdd:TIGR02168  589 NDREILKNIEGFLGVAKDLVKFDPKLRK-ALSYL--LGGVLVVDD------LDNALELAKKLR-----PGYRIVTLDGDl 654

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2565 ---KQSLQMSSDALQKEKQGLSKEIKNLQTQLTALQEEGTLGvyHAQLKAKEEELQRLNMALSSSQKRTADLEEELVCVQ 2641
Cdd:TIGR02168  655 vrpGGVITGGSAKTNSSILERRREIEELEEKIEELEEKIAEL--EKALAELRKELEELEEELEQLRKELEELSRQISALR 732

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2642 KEATRKVSEIEdQLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLTVTKENKDLMAQIQAFGRSMSSLQds 2721
Cdd:TIGR02168  733 KDLARLEAEVE-QLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELR-- 809

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2722 rdhatEELGDLKKKYDASLKELAQL-KEWQDSSREGDVLSQaafplsTSENVLSRLEKLNQQLTSKDEQLLHLSSELESS 2800
Cdd:TIGR02168  810 -----AELTLLNEEAANLRERLESLeRRIAATERRLEDLEE------QIEELSEDIESLAAEIEELEELIEELESELEAL 878

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2801 HNQVQSISKAMTSLQNERDrlwsELEKFRKSEEGKQRAAAPSAASSPAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQ 2880
Cdd:TIGR02168  879 LNERASLEEALALLRSELE----ELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLE 954

                          810       820
                   ....*....|....*....|....*.
gi 1720386946 2881 MSQEMTELRPlkAQLQESQDQTKALQ 2906
Cdd:TIGR02168  955 EAEALENKIE--DDEEEARRRLKRLE 978
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 724-1629 6.77e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 91.66  E-value: 6.77e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  724 KESAEEARSTLAAVTEERDQLLyqvkelDVLAELRARVQELESSLAEAEKQRGLDYESQRAQHNLLTEQIHSLsieaksk 803
Cdd:TIGR02168  171 KERRKETERKLERTRENLDRLE------DILNELERQLKSLERQAEKAERYKELKAELRELELALLVLRLEEL------- 237

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  804 DVKIEALQRELDGVQLQFCEQGTQMKTLQSQLEAKEREVREGTERLRDISQEMEGLSQALSQKELEIAKMDQLLLEKQKD 883
Cdd:TIGR02168  238 REELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQ 317

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  884 VETLQQTIQEKDQQVTElsfsmtekmvqLNEEKFSLGVEIKTLKEQLNLLSRTEEATKEQVEESgagsslklghdESGQE 963
Cdd:TIGR02168  318 LEELEAQLEELESKLDE-----------LAEELAELEEKLEELKEELESLEAELEELEAELEEL-----------ESRLE 375

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  964 GLQQELELLRKESEQRKRKLQAALINRKELLQKVSQLEEELAkvredsrkeipfgenerRKLEEDRENRDDPEEWGTSKW 1043
Cdd:TIGR02168  376 ELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRE-----------------RLQQEIEELLKKLEEAELKEL 438

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1044 REVEASLKQTISEKEVELEGIRRDLKEKTAAEEELQAVVQRMTRDLQSKTKQIDLLqEEVTENQATIQKLVTGTMDAGNG 1123
Cdd:TIGR02168  439 QAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSL-ERLQENLEGFSEGVKALLKNQSG 517

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1124 GSA-APVKETAASSPPGaggeehWKPELE----GRILDLEKDKTQLQKKLQEALiarkailkKAQEKEKQLKEELREQKD 1198
Cdd:TIGR02168  518 LSGiLGVLSELISVDEG------YEAAIEaalgGRLQAVVVENLNAAKKAIAFL--------KQNELGRVTFLPLDSIKG 583

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1199 AyhHLQGQFHEQNKEKENIADQLRQLqcqarESIDRQLPGTGQqepgppaPSLEGISLEDTepaSESDLHAAQPSPPGET 1278
Cdd:TIGR02168  584 T--EIQGNDREILKNIEGFLGVAKDL-----VKFDPKLRKALS-------YLLGGVLVVDD---LDNALELAKKLRPGYR 646

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1279 AALQATVSVAQIQAQLKEMEVEKEELELKVssiaSELAKKSEEVLLLQDQINEQGLEIQNLKAASVEAQAHTELLKQELE 1358
Cdd:TIGR02168  647 IVTLDGDLVRPGGVITGGSAKTNSSILERR----REIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELE 722

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1359 SSQLKVAGL-EHLKTLQPELDALHKHMGQKEEEVNYLYGQLSEKEQTLTTVQTEMVEQERLIKalhtQLEMQAKEHEERL 1437
Cdd:TIGR02168  723 ELSRQISALrKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIE----ELEAQIEQLKEEL 798

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1438 KQAQVEICELKKKPTELEEE----TNAKQQLQRKLQAALISRKEALKENKSLQEQLSSARDAVERLTKSLADVESQVSVQ 1513
Cdd:TIGR02168  799 KALREALDELRAELTLLNEEaanlRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEAL 878

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1514 NQEKDAVLGKLTILQEERDKLIAEMDRFLLENQSLSGSCESLKLALGGLTEDKEKLMEELESVRSSKMAestewqekhkE 1593
Cdd:TIGR02168  879 LNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSE----------E 948

                          890       900       910
                   ....*....|....*....|....*....|....*.
gi 1720386946 1594 LQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQEL 1629
Cdd:TIGR02168  949 YSLTLEEAEALENKIEDDEEEARRRLKRLENKIKEL 984
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1325-2158 2.40e-17

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 89.73  E-value: 2.40e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1325 LQDQINEQGLEIQNLKAASVEAQAHTELlKQELESSQLKVAGLEhLKTLQPELDALHKHMGQKEEEVNYLYGQLSEKEQT 1404
Cdd:TIGR02168  191 LEDILNELERQLKSLERQAEKAERYKEL-KAELRELELALLVLR-LEELREELEELQEELKEAEEELEELTAELQELEEK 268

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1405 LTTVQTEMVEQERLIKALHTQL----------EMQAKEHEERL-------KQAQVEICELKKKPTELEEETNAKQQLQRK 1467
Cdd:TIGR02168  269 LEELRLEVSELEEEIEELQKELyalaneisrlEQQKQILRERLanlerqlEELEAQLEELESKLDELAEELAELEEKLEE 348

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1468 LQAALISRKEALKE-----------NKSLQEQLSSARDAVERLTKSLADVESQVSVQNQEKDAVLGKLTILQEERDKLIA 1536
Cdd:TIGR02168  349 LKEELESLEAELEEleaeleelesrLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLK 428

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1537 EMDRflLENQSLSGSCESLKLALggltedkeklmeelesvrsskmaestewqekhKELQKEYEVLLQSYENVSNEAERIQ 1616
Cdd:TIGR02168  429 KLEE--AELKELQAELEELEEEL--------------------------------EELQEELERLEEALEELREELEEAE 474

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1617 HVVESVRQEKQELYAKLRSTESDKREREKQLQDAEQEMEEMKEKMRKFAKSKQQkiLELEEENDRLRAEAqpvggTGESM 1696
Cdd:TIGR02168  475 QALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSEL--ISVDEGYEAAIEAA-----LGGRL 547

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1697 EALLSSNSSLKEELEKITLEHKTLSKEFEALMAEKDALSEETRNLKLQVEAQVLKQASLEATEKSDEPKDVIEEVTQAVV 1776
Cdd:TIGR02168  548 QAVVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLV 627

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1777 GKSQErDALSDSAKLEDSEAI------------LMGDGAKPGVSETFSSHDDIKNYLQQLDQLKGRIAELEMEKQKDREL 1844
Cdd:TIGR02168  628 VDDLD-NALELAKKLRPGYRIvtldgdlvrpggVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKE 706

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1845 SQALENE-------KNALLTQISAKDSELKLLEEEVTKRTTLNQQIQEELCRVTKLKETAEEEKDDLEErlmnQLAELNG 1917
Cdd:TIGR02168  707 LEELEEEleqlrkeLEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEE----ELAEAEA 782

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1918 SIGNYYQDVTDAQIKNEQLESEMRNLQRCVSELEEEKQQLVKEKTKVESEIRKEYMEKIQGAQKGPANKSHAKELQELLR 1997
Cdd:TIGR02168  783 EIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIE 862

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1998 EKQQEVKQLQKDCIRYLERISALEKTVKALEFVHTESQKDLDVT-------KGNLAQAVEHRKKAQAELSSFKILLDDTQ 2070
Cdd:TIGR02168  863 ELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELeskrselRRELEELREKLAQLELRLEGLEVRIDNLQ 942

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2071 SEAARVLADNLKLKKELQSNKESIKSQIKQKDEDLLRRLEQ-------AEEKHRKEKknmqEKLDALHREKAHVEETLAE 2143
Cdd:TIGR02168  943 ERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKElgpvnlaAIEEYEELK----ERYDFLTAQKEDLTEAKET 1018

                          890
                   ....*....|....*
gi 1720386946 2144 IQVSLTRKDQEMKEL 2158
Cdd:TIGR02168 1019 LEEAIEEIDREARER 1033
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1820-2589 8.96e-17

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 87.80  E-value: 8.96e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1820 YLQQLDQLKGRIAELEMEKQKDRELSQALENEKNALLTQISAKDSELKLLEEEVTKRTTLNQQIQEELCRVTKLKETAEE 1899
Cdd:TIGR02168  230 LVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRE 309

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1900 EKDDLEerlmNQLAELNGSIgnyyqdvtdaqiknEQLESEMRNLQRCVSELEEEKQQLVKEKTKVESEIRKEYMEKiqga 1979
Cdd:TIGR02168  310 RLANLE----RQLEELEAQL--------------EELESKLDELAEELAELEEKLEELKEELESLEAELEELEAEL---- 367

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1980 qkgPANKSHAKELQELLREKQQEVKQLQKDCIRYLERISALEKTVKALEfvhTESQKDLDVTKGNLAQAVEHRKKA-QAE 2058
Cdd:TIGR02168  368 ---EELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLE---DRRERLQQEIEELLKKLEEAELKElQAE 441

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2059 LSSFKILLDDTQSEAARVLADNLKLKKELQSNKESIKS------QIKQKDEDLLRRLEQAEEKHRKEKKNMQEKL----- 2127
Cdd:TIGR02168  442 LEELEEELEELQEELERLEEALEELREELEEAEQALDAaerelaQLQARLDSLERLQENLEGFSEGVKALLKNQSglsgi 521

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2128 -----DALHREK---AHVEETLAE-IQVSLTRKDQEMKELQGSLDSTLAQLAAF------------------TKSMSSLQ 2180
Cdd:TIGR02168  522 lgvlsELISVDEgyeAAIEAALGGrLQAVVVENLNAAKKAIAFLKQNELGRVTFlpldsikgteiqgndreiLKNIEGFL 601

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2181 DDRDRVIDEAKKWERRFG---------DAIQTKEEEVRL--KEENCIALKDQL--RQMAIHMEELKITVSRLEHDKEIWE 2247
Cdd:TIGR02168  602 GVAKDLVKFDPKLRKALSyllggvlvvDDLDNALELAKKlrPGYRIVTLDGDLvrPGGVITGGSAKTNSSILERRREIEE 681

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2248 SKAQTElqhhqkaydKLQEENKELTSQLEDARQLYHDSKNELTKLESELKSLKDQTTDLNNSLEKCKEHENNLEGIIKQQ 2327
Cdd:TIGR02168  682 LEEKIE---------ELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQL 752

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2328 EADIQNCKFSCEQLETDLAASRELTSRLHDEINAKEQKIISLLS--GKEEAIQLAVEELHQQHSKEIKELENLLSQEEEE 2405
Cdd:TIGR02168  753 SKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEelKALREALDELRAELTLLNEEAANLRERLESLERR 832

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2406 NVALEEENKRALEKTNQLTEALEAIKKESFEQKAQLDSFVKSMSSLQDDRDRIvsdyRQLEERHLSAILEKDQLIQDAAA 2485
Cdd:TIGR02168  833 IAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASL----EEALALLRSELEELSEELRELES 908

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2486 ENNKLKEEMRGLRSHMDDLNSENAKLDAEL--------VQYRRDLNEVIAIKDSQQKQLLDAQlQQNKELRNECTKL--- 2554
Cdd:TIGR02168  909 KRSELRRELEELREKLAQLELRLEGLEVRIdnlqerlsEEYSLTLEEAEALENKIEDDEEEAR-RRLKRLENKIKELgpv 987

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|....*.
gi 1720386946 2555 -----------EERLKGLEAEKQSLQMSSDALQKEKQGLSKEIKNL 2589
Cdd:TIGR02168  988 nlaaieeyeelKERYDFLTAQKEDLTEAKETLEEAIEEIDREARER 1033
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1405-2308 9.55e-16

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 84.73  E-value: 9.55e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1405 LTTVQTEMVEQERLIKALHTQLEMQAKEHEERLKqaqVEICELKKKPTELEEETNAKQQLQRKLQAALISRKEALKENKS 1484
Cdd:TIGR02169  179 LEEVEENIERLDLIIDEKRQQLERLRREREKAER---YQALLKEKREYEGYELLKEKEALERQKEAIERQLASLEEELEK 255

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1485 LQEQLSSARDAVERLTKSLADVESQVS-VQNQEKDAVLGKLTILQEERDKLIAEMDRFLLENQSLSGSCESLKLALGGLT 1563
Cdd:TIGR02169  256 LTEEISELEKRLEEIEQLLEELNKKIKdLGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLL 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1564 EDKEKLMEELESVRsskmAESTEWQEKHKELQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQELYAKLrstESDKRER 1643
Cdd:TIGR02169  336 AEIEELEREIEEER----KRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREI---NELKREL 408

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1644 EKqLQDAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEAQPVGGTGESMEALLSSNSS----LKEELEKITLEHKT 1719
Cdd:TIGR02169  409 DR-LQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQelydLKEEYDRVEKELSK 487

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1720 LSKEFEALMAEKDALSEETRNLKLQVEaqvlkqasleatEKSDEPKDVIEEVTQAVVGKSQERDALSDSAkledseailm 1799
Cdd:TIGR02169  488 LQRELAEAEAQARASEERVRGGRAVEE------------VLKASIQGVHGTVAQLGSVGERYATAIEVAA---------- 545

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1800 GDGAKPGVSETfssHDDIKNYLQQLDQLK-GRIAELEMEKQKDRELSQALENEKNALltqisakDSELKLLEEEVTKRTT 1878
Cdd:TIGR02169  546 GNRLNNVVVED---DAVAKEAIELLKRRKaGRATFLPLNKMRDERRDLSILSEDGVI-------GFAVDLVEFDPKYEPA 615

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1879 LNQQIQEelcrvTKLKETAEEEKDDLEERLMNQLA----ELNGSIGNYYQDVTDAQIKNEQLESEMRNLQRCVSELEEEK 1954
Cdd:TIGR02169  616 FKYVFGD-----TLVVEDIEAARRLMGKYRMVTLEgelfEKSGAMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKREL 690

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1955 QQLVKEKTKVESEIrKEYMEKIQGAQKgpankshakelqeLLREKQQEVKQLQKDCIRYLERISALEKTVKALEFVHTES 2034
Cdd:TIGR02169  691 SSLQSELRRIENRL-DELSQELSDASR-------------KIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENV 756

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2035 QKDLDVTKGNLAQAVEHRKKAQAELSSFKILLDDTQSEAARVLADnlKLKKELQSNkESIKSQIKQKDEDLLRRLEQAEe 2114
Cdd:TIGR02169  757 KSELKELEARIEELEEDLHKLEEALNDLEARLSHSRIPEIQAELS--KLEEEVSRI-EARLREIEQKLNRLTLEKEYLE- 832

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2115 khrKEKKNMQEKLDALHREKAHVEETLAEIQVSLTRKDQEMKELQgsldstlAQLAAFTKSMSSLQDDRDRVIDEAKKWE 2194
Cdd:TIGR02169  833 ---KEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELE-------AALRDLESRLGDLKKERDELEAQLRELE 902

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2195 RRfgdaIQTKEEEVRLKEENciaLKDQLRQMAIHMEELKITVSRLEHDKEIWES-----KAQTELQHHQKAYDKLQEENK 2269
Cdd:TIGR02169  903 RK----IEELEAQIEKKRKR---LSELKAKLEALEEELSEIEDPKGEDEEIPEEelsleDVQAELQRVEEEIRALEPVNM 975

                          890       900       910
                   ....*....|....*....|....*....|....*....
gi 1720386946 2270 ELTSQLEDARQLYHDSKNELTKLESELKSLKDQTTDLNN 2308
Cdd:TIGR02169  976 LAIQEYEEVLKRLDELKEKRAKLEEERKAILERIEEYEK 1014
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1817-2658 1.26e-15

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 84.35  E-value: 1.26e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1817 IKNYLQQLDQLKGRIAELEMEKQKDRELSQA----LENEKNALLTQISAKDSELKLLEEEVTKRTTLNQQIQEELCRVTK 1892
Cdd:TIGR02169  193 IDEKRQQLERLRREREKAERYQALLKEKREYegyeLLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQ 272

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1893 LKETAEEEKDDLEERLMNQLaelngsignyyqdvtdaQIKNEQLESEMRNLQRCVSELEEEKQQLVKEKTKVESEIRKEy 1972
Cdd:TIGR02169  273 LLEELNKKIKDLGEEEQLRV-----------------KEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKL- 334

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1973 mekiqgaqkgpanKSHAKELQELLREKQQEVKQLQkdcirylERISALEKTVKALEFVHTESQKDLDVTKGNLAQAVEHR 2052
Cdd:TIGR02169  335 -------------LAEIEELEREIEEERKRRDKLT-------EEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKL 394

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2053 KKAQAELSSFKILLDDTQSEAARVLADNLKLKKELqsnkESIKSQIKQKDEDLLRRLEQAEEKHRKEKKNmQEKLDALHR 2132
Cdd:TIGR02169  395 EKLKREINELKRELDRLQEELQRLSEELADLNAAI----AGIEAKINELEEEKEDKALEIKKQEWKLEQL-AADLSKYEQ 469

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2133 EKAHVEETLAEIQVSLTRKDQEMKELQGSLDSTLAQLAAFTKSMSSLQDDRDRV---IDEAKKWERRFGDAIQTK----- 2204
Cdd:TIGR02169  470 ELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVhgtVAQLGSVGERYATAIEVAagnrl 549

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2205 -----EEEVRLKEenCIALkdqLRQMAI---------HMEELKITVSRLEHDKEIWESKAQTELQHHQKAYDKLQEENKE 2270
Cdd:TIGR02169  550 nnvvvEDDAVAKE--AIEL---LKRRKAgratflplnKMRDERRDLSILSEDGVIGFAVDLVEFDPKYEPAFKYVFGDTL 624

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2271 LTSQLEDARQLYhdSKNELTKLESELKSLKDQTTDLNNSlekckehENNLEGIIKQQEADIQNCKFSCEQLETDLAASRE 2350
Cdd:TIGR02169  625 VVEDIEAARRLM--GKYRMVTLEGELFEKSGAMTGGSRA-------PRGGILFSRSEPAELQRLRERLEGLKRELSSLQS 695

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2351 LTSRLHDEINAKEQKiISLLSGKEEAIQLAVEELHQQHSK---EIKELENLLSQEEEENVALEEENKRALEKTNQLTEAL 2427
Cdd:TIGR02169  696 ELRRIENRLDELSQE-LSDASRKIGEIEKEIEQLEQEEEKlkeRLEELEEDLSSLEQEIENVKSELKELEARIEELEEDL 774

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2428 EAIKKESFEQKA-----QLDSFVKSMSSLQDDRDRIVSDYRQLEERHLSAILEKDQL---IQDAAAENNKLKEEMRGLRS 2499
Cdd:TIGR02169  775 HKLEEALNDLEArlshsRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLekeIQELQEQRIDLKEQIKSIEK 854

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2500 HMDDLNSENAKLDAELVQYRRDLNEVIAIKDSQQKQLldaqlqqnKELRNECTKLEERLKGLEAEKQSLQMSSDALQKEK 2579
Cdd:TIGR02169  855 EIENLNGKKEELEEELEELEAALRDLESRLGDLKKER--------DELEAQLRELERKIEELEAQIEKKRKRLSELKAKL 926

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2580 QGLSKEIKNLQTQLTALQEEG----TLGVYHAQLKAKEEELQRL---NMA----LSSSQKRTADLEEELVCVQKEATRKV 2648
Cdd:TIGR02169  927 EALEEELSEIEDPKGEDEEIPeeelSLEDVQAELQRVEEEIRALepvNMLaiqeYEEVLKRLDELKEKRAKLEEERKAIL 1006

                          890
                   ....*....|..
gi 1720386946 2649 SEIE--DQLKKE 2658
Cdd:TIGR02169 1007 ERIEeyEKKKRE 1018
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1475-2376 5.74e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 82.03  E-value: 5.74e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1475 RKEALKenkslqeQLSSARDAVERLTKSLADVESQV-SVQNQEKDAVlgKLTILQEERDKLiaEMDRFLLENQSLSGSCE 1553
Cdd:TIGR02168  174 RKETER-------KLERTRENLDRLEDILNELERQLkSLERQAEKAE--RYKELKAELREL--ELALLVLRLEELREELE 242

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1554 SLKLALggltEDKEKLMEELESVRSSKMAESTEWQEKHKELQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQELYAKL 1633
Cdd:TIGR02168  243 ELQEEL----KEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQL 318

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1634 RSTESDKREREKQLQDAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEAQPVGGTGESMEALLSSNSSLKEELEKI 1713
Cdd:TIGR02168  319 EELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASL 398

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1714 TLEHKTLSKEFEALMAEKDALSEETRNLKLQVEAQVLKQASLEATEKSDEPKDVIEEVTQAVVGKSQERDALS------D 1787
Cdd:TIGR02168  399 NNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEeaeqalD 478

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1788 SAKLEDSEAILMGDGAKPGVSETFSSHDDIKNYLQQLDQLKGRIAELEMEKQKDRELSQALENEKNALLTQISAKDSELK 1867
Cdd:TIGR02168  479 AAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGGRLQAVVVENLNAA 558

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1868 LLEEEVTKrttlnqqiQEELCRVTKLKETAEEEkDDLEERLMNQLAELNGSIGnYYQDVTDAQIKNEQLESEMRNLQRCV 1947
Cdd:TIGR02168  559 KKAIAFLK--------QNELGRVTFLPLDSIKG-TEIQGNDREILKNIEGFLG-VAKDLVKFDPKLRKALSYLLGGVLVV 628

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1948 SELEEEKQQLVKEKTKVESEIRKEYMEKIQGAQKGPANKSHA---------KELQELLREKQQEVKQLQKDCIRYLERIS 2018
Cdd:TIGR02168  629 DDLDNALELAKKLRPGYRIVTLDGDLVRPGGVITGGSAKTNSsilerrreiEELEEKIEELEEKIAELEKALAELRKELE 708

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2019 ALEKTVKALEFVHTESQKDLDVTKGNLAQAVEHRKKAQAELSSfkilLDDTQSEAARVLADNLKLKKELQSNKESIKSQI 2098
Cdd:TIGR02168  709 ELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQ----LSKELTELEAEIEELEERLEEAEEELAEAEAEI 784

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2099 KQKDEDLLRRLEQAeEKHRKEKKNMQEKLDALHREKAHVEETLAEIQVSLTRKDQEMKELQGSLDSTLAQLAAFTKSMSS 2178
Cdd:TIGR02168  785 EELEAQIEQLKEEL-KALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEE 863

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2179 LQDDRDRVIDEAKKWerrfgdaiqtkEEEVRLKEENCIALKDQLRQMAIHMEELKITVSRLEHDKEiwesKAQTELQHHQ 2258
Cdd:TIGR02168  864 LEELIEELESELEAL-----------LNERASLEEALALLRSELEELSEELRELESKRSELRRELE----ELREKLAQLE 928

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2259 KAYDKLQEENKELTSQL--------EDARQLYHDSKNELTKLESELKSLKDQTTDLNN----SLEKCKEHENNLEGIIKQ 2326
Cdd:TIGR02168  929 LRLEGLEVRIDNLQERLseeysltlEEAEALENKIEDDEEEARRRLKRLENKIKELGPvnlaAIEEYEELKERYDFLTAQ 1008

                          890       900       910       920       930
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1720386946 2327 QEaDIQNCKFSCEQLETDLaaSRELTSRLHD---EINAKEQKIISLLSGKEEA 2376
Cdd:TIGR02168 1009 KE-DLTEAKETLEEAIEEI--DREARERFKDtfdQVNENFQRVFPKLFGGGEA 1058
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 752-1394 6.13e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 78.44  E-value: 6.13e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  752 DVLAELRARVQELESSLAEAEKQRGLDYESQRAQHNLLTEQIHSLSIEAKSKDVKIEALQRELdgvqlqfceqgtqmKTL 831
Cdd:COG1196    193 DILGELERQLEPLERQAEKAERYRELKEELKELEAELLLLKLRELEAELEELEAELEELEAEL--------------EEL 258

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  832 QSQLEAKEREVREGTERLRDISQEMEGLSQALSQKELEIAKMDQLLLEKQKDVETLQQTIQEKDQQVTELsfsmTEKMVQ 911
Cdd:COG1196    259 EAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAEL----EEELEE 334

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  912 LNEEKFSLGVEIKTLKEQLNLLSRTEEATKEQVEEsgagsslklghDESGQEGLQQELELLRKESEQRKRKLQAALINRK 991
Cdd:COG1196    335 LEEELEELEEELEEAEEELEEAEAELAEAEEALLE-----------AEAELAEAEEELEELAEELLEALRAAAELAAQLE 403

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  992 ELLQKVSQLEEELAKVREDSRKEipfgENERRKLEEDRENRddpeewgtskwREVEASLKQTISEKEVELEGIRRDLKEK 1071
Cdd:COG1196    404 ELEEAEEALLERLERLEEELEEL----EEALAELEEEEEEE-----------EEALEEAAEEEAELEEEEEALLELLAEL 468

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1072 TAAEEELQAVVQRMTRDLQSKTKQIDLLQEEVTEnqatiqklvtgtMDAGNGGSAAPVKETAASSPPGAGGEEHWKPELE 1151
Cdd:COG1196    469 LEEAALLEAALAELLEELAEAAARLLLLLEAEAD------------YEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAY 536

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1152 GRILDLEKDKTQLQKKLQEALIARKAILKKAQEKEKQLKEELREQKDAYHHLQGQFHEQNKEKENIADQLRQLQCQARES 1231
Cdd:COG1196    537 EAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYY 616

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1232 IDRQLPGTGQQEPGPPAPSLEGISLEDTEPASESDLHAAQPSPPGETAALQATVSVAQIQAQLKEMEVEKEELELKVSSI 1311
Cdd:COG1196    617 VLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELE 696

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1312 ASELAKKSEEVLLLQDQINEQGLEIQNLKAASVEAQAHTELLKQELESSQLKVAGLEHLKTLQPELDALHKHMGQKEEEV 1391
Cdd:COG1196    697 EALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREI 776


                   ...
gi 1720386946 1392 NYL 1394
Cdd:COG1196    777 EAL 779
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1397-1970 9.36e-14

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 78.05  E-value: 9.36e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1397 QLSEKEQTLTTVQTEMVEQERLIKALHTQLEMQAKEHEERLKQAQVEICELKKKPTELEE----ETNAKQQLQRKLQAAL 1472
Cdd:COG1196    243 ELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQdiarLEERRRELEERLEELE 322

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1473 ISRKEALKENKSLQEQLSSARDAVERLTKSLADVESQVSVQNQEKDAVLGKLTILQEERDKLIAEMDRFLLENQSLSGSC 1552
Cdd:COG1196    323 EELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQL 402

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1553 ESLKLALGGLTEDKEKLMEELESVRSSKMAESTEWQEKHKELQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQELYAK 1632
Cdd:COG1196    403 EELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAEL 482

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1633 LRSTESDKREREKQLQDAEQEMEEMKEKMRKFAKSKQQKILEL--EEENDRLRAEAQPVGGTGESMEALLSSNSSLKEEL 1710
Cdd:COG1196    483 LEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAvaVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAA 562

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1711 EKITLEHKTLSKEFEAL-MAEKDALSEETRNLKLQVEAQVLKQASLEATEKSDEPKDVIEEVTQAVVGKSQERDALSDSA 1789
Cdd:COG1196    563 IEYLKAAKAGRATFLPLdKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTL 642

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1790 KLEDSEAILMGDGAKPGVSETfsshddiknylqqLDQLKGRIAELEMEKQKDRELSQALENEKNALLTQISAKDSELKLL 1869
Cdd:COG1196    643 AGRLREVTLEGEGGSAGGSLT-------------GGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEEREL 709

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1870 EEEVTKRTTLNQQIQEELCRVTKLKETAEEEKDDLEERLMNQLAELNGSIgnyyQDVTDAQIKNEQLESEMRNLQRcV-- 1947
Cdd:COG1196    710 AEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEP----PDLEELERELERLEREIEALGP-Vnl 784

                          570       580
                   ....*....|....*....|....*....
gi 1720386946 1948 ------SELEEEKQQLVKEKTKVESEIRK 1970
Cdd:COG1196    785 laieeyEELEERYDFLSEQREDLEEARET 813
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 678-1252 1.20e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 74.20  E-value: 1.20e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  678 QGELERLKTQVLELETSLHTAEETYKRNLSEKVKEISSLTQLSEEVKESAEEARSTLAAVTEERDQLLYQVKELDVLAEL 757
Cdd:COG1196    238 EAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEER 317

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  758 RARVQELESSLAEAEKQRGLDYESQRAQHNLLTEQIHSLSIEAKSKDVKIEALQRELDGVQLQFCEQGTQMKTLQSQLEA 837
Cdd:COG1196    318 LEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAE 397

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  838 KEREVREGTERLRDISQEMEGLSQALSQKELEIAKMDQLLLEKQKDVETLQQTIQEKDQQVTELsfsmTEKMVQLNEEKF 917
Cdd:COG1196    398 LAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEAL----LELLAELLEEAA 473

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  918 SLGVEIKTLKEQLNLLSRTEEATKE-QVEESGAGSSLKLGHDESGQEGLQQELELLRKESEQRKRKLQAALInrkELLQK 996
Cdd:COG1196    474 LLEAALAELLEELAEAAARLLLLLEaEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALA---AALQN 550

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  997 VSQLEEELAKVREDSRKEIPFGENERRKLEEDRENRDDPeewgtskwrevEASLKQTISEKEVELEGIRRDLKEKTAAEE 1076
Cdd:COG1196    551 IVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALA-----------AALARGAIGAAVDLVASDLREADARYYVLG 619

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1077 ELQAVVQRMTRDLQSKTKQIDLLQEEVTEnqatiqklVTGTMDAGNGGSAapvketaassppgaggeehwkpelEGRILD 1156
Cdd:COG1196    620 DTLLGRTLVAARLEAALRRAVTLAGRLRE--------VTLEGEGGSAGGS------------------------LTGGSR 667

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1157 LEKDKTQLQKKLQEALIARKAILKKAQEKEKQLKEELREQKDAYHHLQGQFHEQNKEKENIADQLRQLQCQARESIDRQL 1236
Cdd:COG1196    668 RELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEEL 747

                          570
                   ....*....|....*.
gi 1720386946 1237 PGTGQQEPGPPAPSLE 1252
Cdd:COG1196    748 LEEEALEELPEPPDLE 763
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1989-2589 2.29e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 73.43  E-value: 2.29e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1989 AKELQELLREKQQEVKQLQKDcirylerisALEKTVKALEFVHTESQKDLDVTKGNLAQAVEHRKKAQAELSSFKILLDD 2068
Cdd:COG1196    215 YRELKEELKELEAELLLLKLR---------ELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEE 285

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2069 TQSEAARVLADNLKLKKELQSNKESIKSQikqkdEDLLRRLEQAEEKHRKEKKNMQEKLDALHREKAHVEETLAEIQVSL 2148
Cdd:COG1196    286 AQAEEYELLAELARLEQDIARLEERRREL-----EERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAEL 360

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2149 TRKDQEMKELQGSLDSTLAQLAAFTKSMSSLQDDRDRvideakkwerrfgdaIQTKEEEVRLKEENCIALKDQLRQMAIH 2228
Cdd:COG1196    361 AEAEEALLEAEAELAEAEEELEELAEELLEALRAAAE---------------LAAQLEELEEAEEALLERLERLEEELEE 425

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2229 MEELKITVSRLEHDKEIWESKAQTELQHHQKAYDKLQEENKELTSQLEDARQLYHDSKNELTKLESELKSLKDQTTDLNN 2308
Cdd:COG1196    426 LEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEG 505

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2309 SLEKCKE-HENNLEGIIKQQEADIQNCKFSCEQLETDLAASRELTSRLHDEINAKE--QKIISLLSGKEEAIQLAVEELH 2385
Cdd:COG1196    506 FLEGVKAaLLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAaiEYLKAAKAGRATFLPLDKIRAR 585

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2386 QQHSKEIKELENLLSQEEEENVALEEENKRALEKTNQLTEALEAIKKES-FEQKAQLDSFVKSMSSLQDDRDRIVSDYRQ 2464
Cdd:COG1196    586 AALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAaLRRAVTLAGRLREVTLEGEGGSAGGSLTGG 665

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2465 LEERHLSAILEKDQLIQDAAAENNKLKEEMRGLRSHMDDLNSENAKLDAELVQYRRDLNEVIAIKDSQQKQLLDAQLQQN 2544
Cdd:COG1196    666 SRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEE 745

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*
gi 1720386946 2545 KELRNEctkleerlkglEAEKQSLQMSSDALQKEKQGLSKEIKNL 2589
Cdd:COG1196    746 ELLEEE-----------ALEELPEPPDLEELERELERLEREIEAL 779
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 2096-2914 2.56e-12

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 73.18  E-value: 2.56e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2096 SQIKQKDEDLLRRLEQAEEKHRKEKKNMQEK---LDALHREKAHVEETLAeiqVSLTRKDQEMKELQGSLDSTLAQLAAF 2172
Cdd:TIGR02169  166 AEFDRKKEKALEELEEVEENIERLDLIIDEKrqqLERLRREREKAERYQA---LLKEKREYEGYELLKEKEALERQKEAI 242

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2173 TKSMSSLQDDRDRVIDEAKKWERRFGDAIQTKEEEVR----LKEENCIALKDQLRQMAIHMEELKITVSRLEHDKEiwes 2248
Cdd:TIGR02169  243 ERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKkikdLGEEEQLRVKEKIGELEAEIASLERSIAEKERELE---- 318

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2249 KAQTELQHHQKAYDKLQEENKELTSQLEDARQlyhdsknELTKLESELKSLKDQTTDLNNSLEkckehennlegiikqqe 2328
Cdd:TIGR02169  319 DAEERLAKLEAEIDKLLAEIEELEREIEEERK-------RRDKLTEEYAELKEELEDLRAELE----------------- 374

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2329 adiqnckfsceQLETDLAASRELTSRLHDEINAKEQKIISLLSGKEEAIqlaveELHQQHSKEIKELENLLsqeeeenva 2408
Cdd:TIGR02169  375 -----------EVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQ-----EELQRLSEELADLNAAI--------- 429

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2409 leeenKRALEKTNQLTEALEAIKKESFEQKAQLDSFVKSMSSLQDDRDRIVSDYRQLEERhlsaILEKDQLIQDAAAENN 2488
Cdd:TIGR02169  430 -----AGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKE----LSKLQRELAEAEAQAR 500

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2489 KLKEEMRGLRSHMDDLNSENA---KLDAELVQYRRD------------LNEVIAIKDSQQKQ----LLDAQLQQNKELRN 2549
Cdd:TIGR02169  501 ASEERVRGGRAVEEVLKASIQgvhGTVAQLGSVGERyataievaagnrLNNVVVEDDAVAKEaielLKRRKAGRATFLPL 580

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2550 ECTKLEERLKGLEAEKQSLQMSSDALQKEKQ---------GLSKEIKNLQT--------QLTALQEE----------GTL 2602
Cdd:TIGR02169  581 NKMRDERRDLSILSEDGVIGFAVDLVEFDPKyepafkyvfGDTLVVEDIEAarrlmgkyRMVTLEGElfeksgamtgGSR 660

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2603 GVYHAQLKAKE--EELQRLNMALSSSQKRTADLEEELVCVQKEATRKVSEIEDqLKKELKHLHHDAGIMRNETETAEERV 2680
Cdd:TIGR02169  661 APRGGILFSRSepAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSD-ASRKIGEIEKEIEQLEQEEEKLKERL 739

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2681 AELARDLVEMEQKLLTVTKENKDLMAQIQAFGRSMSSLQdsrdhatEELGDLKKKYDASlkelaqlkEWQDSSREgdvls 2760
Cdd:TIGR02169  740 EELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLE-------EALNDLEARLSHS--------RIPEIQAE----- 799

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2761 qaafplstsenvlsrLEKLNQQLTSKDEQLLHLSSELESSHNQVQSISKAMTSLQNERDRLWSELEKFRKSEE---GKQR 2837
Cdd:TIGR02169  800 ---------------LSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIEnlnGKKE 864

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1720386946 2838 AAAPSAASSPAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQMSQEMTELRPLKAQLQEsqdqtkALQVMEEELRQ 2914
Cdd:TIGR02169  865 ELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKA------KLEALEEELSE 935
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 51-920 2.97e-12

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 73.17  E-value: 2.97e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946   51 EDALHRLAEAEKLVVELKDIISQKDVQLqqkdEALQEEKKAAE------NKIKKIKLH-AKAKIMSLNKHMEEIKTQgga 123
Cdd:TIGR02168  175 KETERKLERTRENLDRLEDILNELERQL----KSLERQAEKAErykelkAELRELELAlLVLRLEELREELEELQEE--- 247

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  124 alpPEAQAEELSKHNKSSTEEEMEIEKIKHELQEKEKLISSLQAQLDQSeqasqldksSAEMEDFVLMKQQLQEKEELIS 203
Cdd:TIGR02168  248 ---LKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYAL---------ANEISRLEQQKQILRERLANLE 315

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  204 TLQTQLSQTQAEQAAQvvREKDARFETQVRLHEDELLQLVT-QSDVETEMQQKLRVMQRKLEEHEEALLGRAQVVDLLQK 282
Cdd:TIGR02168  316 RQLEELEAQLEELESK--LDELAEELAELEEKLEELKEELEsLEAELEELEAELEELESRLEELEEQLETLRSKVAQLEL 393

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  283 ELTSAEQRNQVLSQQLQLLEAEHNTLKNTMETERQE-SKTLMEKVELEVAERKLSFHNLQEEMHQLQGQLERAGQAQADL 361
Cdd:TIGR02168  394 QIASLNNEIERLEARLERLEDRRERLQQEIEELLKKlEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEA 473

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  362 ETQYSALQQrhktEMEEKTACILSLQKNEQELQSACAALKE--ENSKLLQEKHDQAAESAQAMRQLEDQLQQKSKEISQF 439
Cdd:TIGR02168  474 EQALDAAER----ELAQLQARLDSLERLQENLEGFSEGVKAllKNQSGLSGILGVLSELISVDEGYEAAIEAALGGRLQA 549

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  440 VNKPNLQKNETASQTSLPdvNNEGDQAVMEETVAS---LQKRVVELENEKGALLLSSGELEELKAENEKLSSRI------ 510
Cdd:TIGR02168  550 VVVENLNAAKKAIAFLKQ--NELGRVTFLPLDSIKgteIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLlggvlv 627

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  511 --TLLEAQNRAGEADGTVCEVSTAGTTLLNRSDSSPEENGQavlENTFSQKHKELSVLLVEMKEAQEEIAFLKSQLQGKr 588
Cdd:TIGR02168  628 vdDLDNALELAKKLRPGYRIVTLDGDLVRPGGVITGGSAKT---NSSILERRREIEELEEKIEELEEKIAELEKALAEL- 703

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  589 pegdyevldRREVQLMESEGPPSVTAGDVLCAPSDESSGPAAEEEQAGMKDRHRASEAgplndagmelsspkldgvdksl 668
Cdd:TIGR02168  704 ---------RKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQL---------------------- 752

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  669 avshvcqchQGELERLKTQVLELETSLHTAEETYKRNLSEKVKEISSLTQLSEEVKESAEEARSTLAAVTEERDQllyqv 748
Cdd:TIGR02168  753 ---------SKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEE----- 818

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  749 keldvLAELRARVQELESSLAEAEKQrgldYESQRAQHNLLTEQIHSLSIEAKSKDVKIEALQRELDGVQLQFCEQGTQM 828
Cdd:TIGR02168  819 -----AANLRERLESLERRIAATERR----LEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEAL 889

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  829 KTLQSQLEAKEREVREGTERLRDISQEMEGLSQALSQKELEIAKMDQLLLEKQK----DVETLQQTIQEKDQQVTELSFS 904
Cdd:TIGR02168  890 ALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQErlseEYSLTLEEAEALENKIEDDEEE 969

                          890
                   ....*....|....*.
gi 1720386946  905 MTEKMVQLNEEKFSLG 920
Cdd:TIGR02168  970 ARRRLKRLENKIKELG 985
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1817-2346 4.17e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 72.66  E-value: 4.17e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1817 IKNYLQQLDQLKGRIAELEMEKQKDRELSQALENEKNALLTQISAKDSELKLLEEEVTKRTTLNQQIQEELCRVTKLKET 1896
Cdd:COG1196    234 LRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRE 313

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1897 AEEEKDDLEErlmnQLAELNGSIGNYYQDVTDAQIKNEQLESEMRNLQRCVSELEEEKQQLVKEKTKVESEIRKEYMEKI 1976
Cdd:COG1196    314 LEERLEELEE----ELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELL 389

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1977 qgaqkgpankshakELQELLREKQQEVKQLQKDCIRYLERISALEKTVKALEFVHTESQKDLDVTKGNLAQAVEHRKKAQ 2056
Cdd:COG1196    390 --------------EALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELE 455

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2057 AELSSFKILLDDTQSEAARVLADNLKLKKELQSNKESIKSQIKQKDEDLLrRLEQAEEKHRKEKKNMQEKLDALHREKAH 2136
Cdd:COG1196    456 EEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEG-FLEGVKAALLLAGLRGLAGAVAVLIGVEA 534

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2137 VEETLAE------IQVSLTRKDQEMKELQGSLDSTLAQLAAF-------------TKSMSSLQDDRDRVIDEAKKWERRF 2197
Cdd:COG1196    535 AYEAALEaalaaaLQNIVVEDDEVAAAAIEYLKAAKAGRATFlpldkiraraalaAALARGAIGAAVDLVASDLREADAR 614

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2198 GDAIQTKEEEVRLKEENCIA-------LKDQLRQMAIHMEELKITVSRLEHDKEIWESKAQTELQHHQKAYDKLQEENKE 2270
Cdd:COG1196    615 YYVLGDTLLGRTLVAARLEAalrravtLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELE 694

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1720386946 2271 LTSQLEDARQLYHDSKNELTKLESELKSLKDQTTDLNNSLEKCKEHENNLEGIIKQQEADIQNCKFSCEQLETDLA 2346
Cdd:COG1196    695 LEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELE 770
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1593-2375 4.51e-12

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 72.41  E-value: 4.51e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1593 ELQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQELyaklrSTESDKREREKQLQDaeqemeeMKEKMRKFAKSKQQKI 1672
Cdd:TIGR02169  167 EFDRKKEKALEELEEVEENIERLDLIIDEKRQQLERL-----RREREKAERYQALLK-------EKREYEGYELLKEKEA 234

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1673 LEleeendrlraeaqpvggtgESMEALLSSNSSLKEELEKITLEHKTLSKEFEALMAEKDAL--------SEETRNLKLQ 1744
Cdd:TIGR02169  235 LE-------------------RQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELnkkikdlgEEEQLRVKEK 295

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1745 VEAQVLKQASLEAT--EKSDEPKDVIEEVTQAVVGKSQERDALSDSAKLEDSEAILmgdgaKPGVSETFSSHDDIKNYL- 1821
Cdd:TIGR02169  296 IGELEAEIASLERSiaEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKR-----RDKLTEEYAELKEELEDLr 370

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1822 QQLDQLKGRIAELEMEKQKDRELSQALENEKNALLTQISAKDSELKLLEEEVTKrttLNQQIQEELCRVTKLKETAEEEK 1901
Cdd:TIGR02169  371 AELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELAD---LNAAIAGIEAKINELEEEKEDKA 447

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1902 DDLEErLMNQLAELNGSIGNYYQDVTDAQIKNEQLESEMRNLQRCVSELEEEKQQLVKEKT--KVESEIRKEYMEKIQG- 1978
Cdd:TIGR02169  448 LEIKK-QEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRggRAVEEVLKASIQGVHGt 526

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1979 -AQKGPANKSHAKELQELLREKQQEV----KQLQKDCIRYLERISALEKTVKAL-EFVHTESQKDLDVTKGNLAQAVEHR 2052
Cdd:TIGR02169  527 vAQLGSVGERYATAIEVAAGNRLNNVvvedDAVAKEAIELLKRRKAGRATFLPLnKMRDERRDLSILSEDGVIGFAVDLV 606

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2053 KKAQAELSSFKILLDDT----QSEAARVLADNLK---LKKEL---------QSNKESIKSQIKQKDEDLLRRLEQAEEKH 2116
Cdd:TIGR02169  607 EFDPKYEPAFKYVFGDTlvveDIEAARRLMGKYRmvtLEGELfeksgamtgGSRAPRGGILFSRSEPAELQRLRERLEGL 686

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2117 RKEKKNMQEKLDALHREKAHVEETLAEIQVSLTRKDQEMKELQGSLDSTLAQLAAFTKSMSSLQDDRDRVIDEAKKWERR 2196
Cdd:TIGR02169  687 KRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEAR 766

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2197 FGDaIQTKEEEVRLKEENCIA--LKDQLRQMAIHMEELKITVSRLE---HDKEIWESKAQTELQHHQKAYDKLQEENKEL 2271
Cdd:TIGR02169  767 IEE-LEEDLHKLEEALNDLEArlSHSRIPEIQAELSKLEEEVSRIEarlREIEQKLNRLTLEKEYLEKEIQELQEQRIDL 845

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2272 TSQLEDARQLYHDSKNELTKLESELKSLKDQTTDLNNSLEKCKEHENNLEGIIKQQEADIQNCKFSCEQLETDLAASREL 2351
Cdd:TIGR02169  846 KEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAK 925

                          810       820
                   ....*....|....*....|....
gi 1720386946 2352 TSRLHDEINAKEQKIISLLSGKEE 2375
Cdd:TIGR02169  926 LEALEEELSEIEDPKGEDEEIPEE 949
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2053-2618 5.74e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 71.89  E-value: 5.74e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2053 KKAQAELSSFKI-LLDDTQSEAARVLADNLKLKKELQSNKESIKSQIKQKDEDLLRrLEQAEEKHRKEKKNMQEKLDALH 2131
Cdd:COG1196    223 KELEAELLLLKLrELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEE-LELELEEAQAEEYELLAELARLE 301

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2132 REKAHVEETLAEIQVSLTRKDQEMKELQGSLDSTLAQLAAFTKSMSSLQDDRDRVIDEAKKWERRFGDAIQTKEEEVRLK 2211
Cdd:COG1196    302 QDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEEL 381

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2212 EENCIALKDQLRQMAIHMEELKITVSRLEhdkeiwesKAQTELQHHQKAYDKLQEENKELTSQLEDARQLYHDSKNELTK 2291
Cdd:COG1196    382 EELAEELLEALRAAAELAAQLEELEEAEE--------ALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAE 453

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2292 LESELKSLKDQTTDLNNSLEKCKEHENNLEGIIKQQEAdiqnckfsceQLETDLAASRELTSRLHDEINAKEQKIISLLS 2371
Cdd:COG1196    454 LEEEEEALLELLAELLEEAALLEAALAELLEELAEAAA----------RLLLLLEAEADYEGFLEGVKAALLLAGLRGLA 523

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2372 GKEEAIQLAVEELhqqhSKEIKELENLLSQEEEENVALEEENKRALEKTNQLTEA----LEAIKKESFEQKAQLDSFVKS 2447
Cdd:COG1196    524 GAVAVLIGVEAAY----EAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRAtflpLDKIRARAALAAALARGAIGA 599

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2448 MSSLQDDRDRIVSDYRQLEERHLSAILEKDQLIQDAAAENNKLKEEMRGLRSHMDDLNSENAKLDAELVQYRRDLNEVIA 2527
Cdd:COG1196    600 AVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEA 679

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2528 IKDSQQKQLLDAQLQQNKELRNEctkLEERLKGLEAEKQSLQMSSDALQKEKQGLSKEIKNLQTQLTALQEEGTLGVYHA 2607
Cdd:COG1196    680 ELEELAERLAEEELELEEALLAE---EEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEEL 756

                          570
                   ....*....|.
gi 1720386946 2608 QLKAKEEELQR 2618
Cdd:COG1196    757 PEPPDLEELER 767
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1414-2007 7.72e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 71.51  E-value: 7.72e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1414 EQERLIKALHTQLEMQAKEHEERLKQAQVEicelkkkptELEEETNAKQQLQRKLQAALISRKEALKEnksLQEQLSSAR 1493
Cdd:COG1196    220 EELKELEAELLLLKLRELEAELEELEAELE---------ELEAELEELEAELAELEAELEELRLELEE---LELELEEAQ 287

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1494 DAVERLTKSLADVESQVSVQNQEKDAvlgkltiLQEERDKLIAEMDRfllenqslsgsceslklalggLTEDKEKLMEEL 1573
Cdd:COG1196    288 AEEYELLAELARLEQDIARLEERRRE-------LEERLEELEEELAE---------------------LEEELEELEEEL 339

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1574 EsvrsskmaestEWQEKHKELQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQELYAKLRSTESDKREREKQLQDAEQE 1653
Cdd:COG1196    340 E-----------ELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEA 408

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1654 MEEMKEKMRKFAKSKQQKILELEEENDRLRAEAQPVggtgESMEALLSSNSSLKEELEKITLEHKTLSKEFEALMAEKDA 1733
Cdd:COG1196    409 EEALLERLERLEEELEELEEALAELEEEEEEEEEAL----EEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLE 484

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1734 LSEETRNLKLQVEAQVLKQASLEATEKSDEPKDVIEEVTQAVvgksqeRDALSDSAKLEDSEAILMGDGAKPGVSETFSS 1813
Cdd:COG1196    485 ELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAV------AVLIGVEAAYEAALEAALAAALQNIVVEDDEV 558

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1814 HDDIKNYLQQldQLKGRIAELEMEKQKDRELSQALEnEKNALLTQISAKDSELKLLEEevtkRTTLNQQIQEELCRVTKL 1893
Cdd:COG1196    559 AAAAIEYLKA--AKAGRATFLPLDKIRARAALAAAL-ARGAIGAAVDLVASDLREADA----RYYVLGDTLLGRTLVAAR 631

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1894 KETAEEEKDDLEERLmnQLAELNGSIGNYYQDVTDAQIKNEQLESEMRNLQRCVSELEEEKQQLVKEKTKVESEIRKEYM 1973
Cdd:COG1196    632 LEAALRRAVTLAGRL--REVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEEREL 709

                          570       580       590
                   ....*....|....*....|....*....|....
gi 1720386946 1974 EKIQGAQKGPANKSHAKELQELLREKQQEVKQLQ 2007
Cdd:COG1196    710 AEAEEERLEEELEEEALEEQLEAEREELLEELLE 743
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1564-2437 1.07e-11

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 71.25  E-value: 1.07e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1564 EDKEKLMEELESVRSSKMAESTEWQEKHKELQKeyevllqsYENVSNEAERIQHVVESVRQ-EKQELYAKLRSTESDKRE 1642
Cdd:TIGR02169  170 RKKEKALEELEEVEENIERLDLIIDEKRQQLER--------LRREREKAERYQALLKEKREyEGYELLKEKEALERQKEA 241

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1643 REKQLQDAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEaqpvgGTGESMEallssnssLKEELEKITLEHKTLSK 1722
Cdd:TIGR02169  242 IERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDL-----GEEEQLR--------VKEKIGELEAEIASLER 308

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1723 EFEALMAEKDALSEETRNLKLQVEAQVLKQASLEatEKSDEPKDVIEEVTQAVVGKSQERDALSDSAKLEDSEAilmgdg 1802
Cdd:TIGR02169  309 SIAEKERELEDAEERLAKLEAEIDKLLAEIEELE--REIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEF------ 380

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1803 akpgvSETFSSHDDIKnylQQLDQLKGRIAELEMEKQKDRELSQALENEKNALLTQISAKDSELKLLEEEVTKRTTLNQQ 1882
Cdd:TIGR02169  381 -----AETRDELKDYR---EKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKK 452

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1883 IQEELCRVTKLKETAEEEKDDLEERLmnqlaelngsignyyqdvtdaqiknEQLESEMRNLQRCVSELEEEKQQLVKEKT 1962
Cdd:TIGR02169  453 QEWKLEQLAADLSKYEQELYDLKEEY-------------------------DRVEKELSKLQRELAEAEAQARASEERVR 507

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1963 --KVESEIRKEYMEKIQG--AQKGPANKSHAKELQELLREKQQEV----KQLQKDCIRYLERISALEKTVKAL-EFVHTE 2033
Cdd:TIGR02169  508 ggRAVEEVLKASIQGVHGtvAQLGSVGERYATAIEVAAGNRLNNVvvedDAVAKEAIELLKRRKAGRATFLPLnKMRDER 587

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2034 SQKDLDVTKGNLAQAVEHRKKAQAELSSFKILLDDT----QSEAARVLADNLK---LKKEL---------QSNKESIKSQ 2097
Cdd:TIGR02169  588 RDLSILSEDGVIGFAVDLVEFDPKYEPAFKYVFGDTlvveDIEAARRLMGKYRmvtLEGELfeksgamtgGSRAPRGGIL 667

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2098 IKQKDEDLLRRLEQAEEKHRKEKKNMQEKLDALHREKAHVEETLAEIQVSLTRKDQEMKELQGSLDSTLAQLAAFTKSMS 2177
Cdd:TIGR02169  668 FSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLS 747

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2178 SLQDDRDRVIDEAKKWERRFGDaIQTKEEEVRLKEENCIA--LKDQLRQMAIHMEELKITVSRLE---HDKEIWESKAQT 2252
Cdd:TIGR02169  748 SLEQEIENVKSELKELEARIEE-LEEDLHKLEEALNDLEArlSHSRIPEIQAELSKLEEEVSRIEarlREIEQKLNRLTL 826

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2253 ELQHHQKAYDKLQEENKELTSQLEDARQLYHDSKNELTKLESELKSLKDQTTDLNNSLEKCKEHENNLEGIIKQQEADIQ 2332
Cdd:TIGR02169  827 EKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIE 906

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2333 NCKFSCEQLETDLAASRELTSRLHDEINAKEQKIISLLSGKEEA-----IQLAVEELHQQHSK----------EIKELEN 2397
Cdd:TIGR02169  907 ELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEElsledVQAELQRVEEEIRAlepvnmlaiqEYEEVLK 986

                          890       900       910       920
                   ....*....|....*....|....*....|....*....|
gi 1720386946 2398 LLSQEEEENVALEEENKRALEKTNQLTEALEAIKKESFEQ 2437
Cdd:TIGR02169  987 RLDELKEKRAKLEEERKAILERIEEYEKKKREVFMEAFEA 1026
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2249-3050 2.82e-11

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 70.09  E-value: 2.82e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2249 KAQTELQHHQKAYDKLQEENKELTSQLE------DARQLYHDSKNELTKLESELksLKDQTTDLNNSLEKCKEHENNLEG 2322
Cdd:TIGR02168  176 ETERKLERTRENLDRLEDILNELERQLKslerqaEKAERYKELKAELRELELAL--LVLRLEELREELEELQEELKEAEE 253

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2323 IIKQQEADIQNCKfscEQLETDLAASRELTSRLhDEINAKEQKIISLLSGKEEAIQLAVEELHQQHsKEIKELENLLSQE 2402
Cdd:TIGR02168  254 ELEELTAELQELE---EKLEELRLEVSELEEEI-EELQKELYALANEISRLEQQKQILRERLANLE-RQLEELEAQLEEL 328

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2403 EEENVALEEENKRALEKTNQLTEALEAIKKESFEQKAQLDSFVKSMSSLQDDRDRIVSDYRQLEERHLSA---ILEKDQL 2479
Cdd:TIGR02168  329 ESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLnneIERLEAR 408

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2480 IQDAAAENNKLKEEMRGLRSHMDDlnsenakldAELVQYRRDLNEVIAIKDSQQKQLLDAQlQQNKELRNECTKLEERLK 2559
Cdd:TIGR02168  409 LERLEDRRERLQQEIEELLKKLEE---------AELKELQAELEELEEELEELQEELERLE-EALEELREELEEAEQALD 478

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2560 GLEAEKQSLQMSSDALQK---EKQGLSKEIKNLQtqLTALQEEGTLGVYHAQLKAKEEELQRLNMALSSS--QKRTADLE 2634
Cdd:TIGR02168  479 AAERELAQLQARLDSLERlqeNLEGFSEGVKALL--KNQSGLSGILGVLSELISVDEGYEAAIEAALGGRlqAVVVENLN 556

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2635 EELVCVQ---KEATRKVS----------EIEDQLKKELKHLHHDAGIMRNETETAE----------------ERVAELAR 2685
Cdd:TIGR02168  557 AAKKAIAflkQNELGRVTflpldsikgtEIQGNDREILKNIEGFLGVAKDLVKFDPklrkalsyllggvlvvDDLDNALE 636

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2686 DLVEMEQKLLTVTKENKDLMAQ-IQAFGR-----SMSSLQDSRDHATEELGDLKKKYDASLKELAQLKEWQDSSREgdVL 2759
Cdd:TIGR02168  637 LAKKLRPGYRIVTLDGDLVRPGgVITGGSaktnsSILERRREIEELEEKIEELEEKIAELEKALAELRKELEELEE--EL 714

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2760 SQAAFPLSTSENVLSRLEKLNQQLTSKDEQLLHLSSELESSHNQVQSISKAMTSLQNERDRLWSELEKFRKSEEGKQRAA 2839
Cdd:TIGR02168  715 EQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQL 794

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2840 APSAASSPAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQMSQEMTELRPLKAQLQESQDQTkALQVMEEELRQENLSW 2919
Cdd:TIGR02168  795 KEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESL-AAEIEELEELIEELES 873

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2920 QHELRQLRMEKNSWELHERRMKEQFLMA-ISDKDQQLGHLQSLLRELRSS--------SQAQILSTQYQRQASPETSASL 2990
Cdd:TIGR02168  874 ELEALLNERASLEEALALLRSELEELSEeLRELESKRSELRRELEELREKlaqlelrlEGLEVRIDNLQERLSEEYSLTL 953

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1720386946 2991 DGSQKLVYETELLRTQLNDSLKEIHQKELRIQQLN----SKFSQLLEEKNVLSTQLSDASQSLR 3050
Cdd:TIGR02168  954 EEAEALENKIEDDEEEARRRLKRLENKIKELGPVNlaaiEEYEELKERYDFLTAQKEDLTEAKE 1017
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 255-1078 3.39e-11

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 69.71  E-value: 3.39e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  255 KLRVMQRKLEEHEEALLGRAQVVDLLQKELTSAEQRNQVLSQQLQLLEAEHNTLKNTMETERQESKTLMEKVELEVAERK 334
Cdd:TIGR02169  178 ELEEVEENIERLDLIIDEKRQQLERLRREREKAERYQALLKEKREYEGYELLKEKEALERQKEAIERQLASLEEELEKLT 257

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  335 LSFHNLQEEMHQLQGQLEragQAQADLETQYSALQQRHKTEMEEKTACILSLQKNEQELQSACAALKEENSKLLQEKHDQ 414
Cdd:TIGR02169  258 EEISELEKRLEEIEQLLE---ELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKL 334

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  415 AAESAQAMRQLEDQLQQKSKEISQFVNkpnLQKNETASQTSLPDVNNEGDQAVMEetVASLQKRVVELENEKGALLlssG 494
Cdd:TIGR02169  335 LAEIEELEREIEEERKRRDKLTEEYAE---LKEELEDLRAELEEVDKEFAETRDE--LKDYREKLEKLKREINELK---R 406

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  495 ELEELKAENEKLSSRITLLEAQNRAGEADgtVCEVSTAGTTLLNRSDSSPEENGQAV-----LENTFSQKHKELSVLLVE 569
Cdd:TIGR02169  407 ELDRLQEELQRLSEELADLNAAIAGIEAK--INELEEEKEDKALEIKKQEWKLEQLAadlskYEQELYDLKEEYDRVEKE 484

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  570 MKEAQEEIAFLKSQLQGKRPEgdyeVLDRREVQLMESEGPPSV--------------------TAGDVLCAPSDESSGPA 629
Cdd:TIGR02169  485 LSKLQRELAEAEAQARASEER----VRGGRAVEEVLKASIQGVhgtvaqlgsvgeryataievAAGNRLNNVVVEDDAVA 560

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  630 AEEEQagMKDRHRASEAG--PLN---DAGMELSSPKLDGVDKSL------------AVSHVCQ--------------CHQ 678
Cdd:TIGR02169  561 KEAIE--LLKRRKAGRATflPLNkmrDERRDLSILSEDGVIGFAvdlvefdpkyepAFKYVFGdtlvvedieaarrlMGK 638

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  679 GELERLKTQVLELETSLHTAEETYKRNLSEKVKEISSLTQLSEEvKESAEEARSTLAAVTEERDQLLYqvkeldvlaELR 758
Cdd:TIGR02169  639 YRMVTLEGELFEKSGAMTGGSRAPRGGILFSRSEPAELQRLRER-LEGLKRELSSLQSELRRIENRLD---------ELS 708

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  759 ARVQELESSLAEAEKQRgldyESQRAQHNLLTEQIHSLSIEAKSKDVKIEALQRELDGVQLQFCEQGTQMKTLQSQLEAK 838
Cdd:TIGR02169  709 QELSDASRKIGEIEKEI----EQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDL 784

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  839 ERevREGTERLRDISQEMEGLSQALSQKELEIAKMDQLLLEKQKDVETLQQTIQEKDQQVTELSF---SMTEKMVQLNEE 915
Cdd:TIGR02169  785 EA--RLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEqikSIEKEIENLNGK 862

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  916 KFSLGVEIKTLKEQLNLLSRTEEATKEQVEESGAgsslKLGHDESGQEGLQQELELLRKESEQRKRKLQAalinrkeLLQ 995
Cdd:TIGR02169  863 KEELEEELEELEAALRDLESRLGDLKKERDELEA----QLRELERKIEELEAQIEKKRKRLSELKAKLEA-------LEE 931

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  996 KVSQLEEELAKVREDSRKEIPFG--ENERRKLEEDRENRDDPEEWGTSKWREVEASLKQtISEKEVELEGIRRDLKEKTA 1073
Cdd:TIGR02169  932 ELSEIEDPKGEDEEIPEEELSLEdvQAELQRVEEEIRALEPVNMLAIQEYEEVLKRLDE-LKEKRAKLEEERKAILERIE 1010


                   ....*
gi 1720386946 1074 AEEEL 1078
Cdd:TIGR02169 1011 EYEKK 1015
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1351-2144 7.35e-11

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 68.56  E-value: 7.35e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1351 ELLKQELESSQLKVAGLE-HLKTLQPELDALHKHMGQKEEEVNYLYGQLSEK-EQTLTTVQTEMVE---QERLIKALHTQ 1425
Cdd:TIGR02169  233 EALERQKEAIERQLASLEeELEKLTEEISELEKRLEEIEQLLEELNKKIKDLgEEEQLRVKEKIGEleaEIASLERSIAE 312

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1426 LEMQAKEHEERLKQAQVEICELKKKPTELEEETNAKQQLQRKLQAALISRKEalKENKSLQEqlssardaverltksLAD 1505
Cdd:TIGR02169  313 KERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKE--ELEDLRAE---------------LEE 375

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1506 VESQVSVQNQEKDAVLGKLTILQEERDKLIAEMDRFLLENQSLSGSCESLKLALGGLTEDKEKLMEELESVRsskmAEST 1585
Cdd:TIGR02169  376 VDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKA----LEIK 451

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1586 EWQEKHKELQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQELYAKLRSTESDKREREKQLQDAEQEMEEMKEKMRKFA 1665
Cdd:TIGR02169  452 KQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLG 531

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1666 KSKQQKILELE-EENDRLRAEAQPVGGTGESMEALLSSNSSLKEE---LEKITLEHKTLSKefealMAEKDALS------ 1735
Cdd:TIGR02169  532 SVGERYATAIEvAAGNRLNNVVVEDDAVAKEAIELLKRRKAGRATflpLNKMRDERRDLSI-----LSEDGVIGfavdlv 606

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1736 ---EETRNLKLQVEAQVLKQASLEATEKSDE-------PKDVIEEVTQAVVGKSQERDALSDSAKLEDSEailmgdgakP 1805
Cdd:TIGR02169  607 efdPKYEPAFKYVFGDTLVVEDIEAARRLMGkyrmvtlEGELFEKSGAMTGGSRAPRGGILFSRSEPAEL---------Q 677

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1806 GVSETFSSHDDIKNYLQQ-LDQLKGRIAELEMEKQKDRELSQALENEKNALLTQISAKDSELKLLEEEVtkrttlnQQIQ 1884
Cdd:TIGR02169  678 RLRERLEGLKRELSSLQSeLRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDL-------SSLE 750

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1885 EELCRVTKLKETAEEEKDDLEERLMNQLAELNgsignyyqdvtdaQIKNEQLESEMRNLQRCVSELEEEKQQLVKEKTKV 1964
Cdd:TIGR02169  751 QEIENVKSELKELEARIEELEEDLHKLEEALN-------------DLEARLSHSRIPEIQAELSKLEEEVSRIEARLREI 817

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1965 ESEIRKEYMEKIQGAQKGPANKSHAKELQELLREKQQEVKQLQKDCIRYLERISALEKTVKALEFVHTESQKDLDVTKGN 2044
Cdd:TIGR02169  818 EQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQ 897

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2045 LAQAVEHRKKAQAELSSFKILLDDTQsEAARVLADNLK----LKKELQSNKESIKS--QIKQKDEDLLRRLEQAE----- 2113
Cdd:TIGR02169  898 LRELERKIEELEAQIEKKRKRLSELK-AKLEALEEELSeiedPKGEDEEIPEEELSleDVQAELQRVEEEIRALEpvnml 976

                          810       820       830
                   ....*....|....*....|....*....|....*.
gi 1720386946 2114 -----EKHRKEKKNMQEKLDALHREKAHVEETLAEI 2144
Cdd:TIGR02169  977 aiqeyEEVLKRLDELKEKRAKLEEERKAILERIEEY 1012
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 204-792 8.37e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 68.42  E-value: 8.37e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  204 TLQTQLSQTQAEQAA---QVVREKDARFETQVRLHEDELLQLVTQSDVE----TEMQQKLRVMQRKLEEHEEALLGRAQV 276
Cdd:COG1196    217 ELKEELKELEAELLLlklRELEAELEELEAELEELEAELEELEAELAELeaelEELRLELEELELELEEAQAEEYELLAE 296

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  277 VDLLQKELTSAEQRNQVLSQQLQLLEAEHNTLKNTMETERQESKTLMEKVELEVAERKLsfhnLQEEMHQLQGQLERAGQ 356
Cdd:COG1196    297 LARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEE----AEAELAEAEEALLEAEA 372

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  357 AQADLETQYSALQQRHKTEMEEktacILSLQKNEQELQSACAALKEENSKLLQEKHDQAAESAQAMRQLEDQLQQKSKEI 436
Cdd:COG1196    373 ELAEAEEELEELAEELLEALRA----AAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAA 448

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  437 SQFVNKPNLQKNETASQTSLPDVNNEGDQAVMEETVASLQKRVVELENEKGALLLSSGELEELKAENEKLSSRITLLEAQ 516
Cdd:COG1196    449 EEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAV 528

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  517 NRAGEADGTVCEVSTAGTTLLNRSDSSPEENGQAVLENTFSQKHKELSVLLVEMKEAQEEIAFLKSQLQGKRPEGDYEVL 596
Cdd:COG1196    529 LIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDL 608

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  597 DRREVQLMESEGPPSVTAGDVLCAPSDESSGPAAEEEQAGMKDRHRASEAGPLNDAGMELSSPKLDGVDKSLAVSHVCQC 676
Cdd:COG1196    609 READARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERL 688

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  677 HQGELERLKTQVLELETSLHTAEETYKRNLSEKVKEISSLTQLSEEVKESAEEarstLAAVTEERDQLLYQVKELDVLAE 756
Cdd:COG1196    689 AEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEEL----LEEEELLEEEALEELPEPPDLEE 764

                          570       580       590
                   ....*....|....*....|....*....|....*....
gi 1720386946  757 LRARVQELESSLAEAEK--QRGLD-YESQRAQHNLLTEQ 792
Cdd:COG1196    765 LERELERLEREIEALGPvnLLAIEeYEELEERYDFLSEQ 803
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2202-2746 1.63e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 67.27  E-value: 1.63e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2202 QTKEEEVRLKEENCIALKDQLRQMAIhmEELKITVSRLEHDKEiwesKAQTELQHHQKAYDKLQEENKELTSQLEDARQL 2281
Cdd:COG1196    216 RELKEELKELEAELLLLKLRELEAEL--EELEAELEELEAELE----ELEAELAELEAELEELRLELEELELELEEAQAE 289

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2282 YHDSKNELTKLESELKSLKDQTTDLNNSLEKCKEHENNLEGIIKQQEADIQNCKFSCEQLETDLAASRELTSRLHDEINA 2361
Cdd:COG1196    290 EYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLE 369

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2362 KEQKIISLLSGKEEAIQLAVEELHQQ--HSKEIKELENLLSQEEEENVALEEENKRALEKTNQLTEALEAIKKESFEQKA 2439
Cdd:COG1196    370 AEAELAEAEEELEELAEELLEALRAAaeLAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAE 449

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2440 QLDSFVKSMSSLQDDRDRIVSDYRQLEERHLSAILEKDQLIQDAAAENN---------------KLKEEMRGLRSHMDDL 2504
Cdd:COG1196    450 EEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEaeadyegflegvkaaLLLAGLRGLAGAVAVL 529

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2505 NSENAKLDAELVQYRRDLNEVIAIKDSQQKQLLDAQLQQNKELRNECTKLEERLKGLEAEKQSLQMSSDALQKEKQGLSK 2584
Cdd:COG1196    530 IGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLR 609

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2585 EIKNLQTQLTALQEEGTL--------GVYHAQLKAKEEELQRLNMALSSSQKRTADLEEELVCVQKEATRKVSEIEDQLK 2656
Cdd:COG1196    610 EADARYYVLGDTLLGRTLvaarleaaLRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLA 689

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2657 KELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLTVTKENKDLMAQIQAFGRSMSSLQDSRDHATEELGDLKKKY 2736
Cdd:COG1196    690 EEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELEREL 769

                          570
                   ....*....|
gi 1720386946 2737 DASLKELAQL 2746
Cdd:COG1196    770 ERLEREIEAL 779
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 728-1577 1.75e-10

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 67.40  E-value: 1.75e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  728 EEARSTLAAVTEERDQLLYQVKELD-VLAELRARVQELESSLAEAEKQRGLDYESQRAQHNLLTEQIHSLSIEAKSKDVK 806
Cdd:TIGR02169  166 AEFDRKKEKALEELEEVEENIERLDlIIDEKRQQLERLRREREKAERYQALLKEKREYEGYELLKEKEALERQKEAIERQ 245

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  807 IEALQRELDGVQLQFCEQGTQMKTLQSQLEAKEREVRE-GTERLRDISQEMEGLSQALSQKELEIAKMDQLLLEKQKDVE 885
Cdd:TIGR02169  246 LASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDlGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLA 325

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  886 TLQQTIQEKDQQVTELSfsmtEKMVQLNEEKFSLGVEIKTLKEQLNLLsrteEATKEQVEESGAGSSLKLGHDESGQEGL 965
Cdd:TIGR02169  326 KLEAEIDKLLAEIEELE----REIEEERKRRDKLTEEYAELKEELEDL----RAELEEVDKEFAETRDELKDYREKLEKL 397

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  966 QQELELLRKESEQRKRKLQAALINRKELLQKVSQLEE---ELAKVREDSRKEIPFGENERRKLEEDRENRDDPEEWGTSK 1042
Cdd:TIGR02169  398 KREINELKRELDRLQEELQRLSEELADLNAAIAGIEAkinELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEE 477

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1043 WREVE---ASLKQTISEKEVELEGIRRDLKEKTAAEEELQAVVQRM---TRDLQSKTKQIDL---------LQEEVTENQ 1107
Cdd:TIGR02169  478 YDRVEkelSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVhgtVAQLGSVGERYATaievaagnrLNNVVVEDD 557

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1108 ATIQKLVTgTMDAGNGGSAA--PVKETAASSPPGAggeehwKPELEGrILDLEKDKTQLQKKLQEAL--IARKAILKKAQ 1183
Cdd:TIGR02169  558 AVAKEAIE-LLKRRKAGRATflPLNKMRDERRDLS------ILSEDG-VIGFAVDLVEFDPKYEPAFkyVFGDTLVVEDI 629

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1184 EKEKQLKEELReqkdaYHHLQGQFHEQNKEKENIADQLRQLQCQAResidrqlpgtgQQEPGPPAPSLEGISLEDTEPAS 1263
Cdd:TIGR02169  630 EAARRLMGKYR-----MVTLEGELFEKSGAMTGGSRAPRGGILFSR-----------SEPAELQRLRERLEGLKRELSSL 693

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1264 ESDLHAAQPSPPGETAALQ-ATVSVAQIQAQLKEMEVEKEELELKVSSIASELAKKSEEVLLLQDQINEQGLEIQNLKAA 1342
Cdd:TIGR02169  694 QSELRRIENRLDELSQELSdASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEED 773

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1343 SVEAQAHTELLKQELESSQLK--VAGLEHLKTLQPELDALHKHMGQKEEEVNYLYGQLSEKEQTLTTVQTEMVEQERLIK 1420
Cdd:TIGR02169  774 LHKLEEALNDLEARLSHSRIPeiQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIE 853

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1421 ALHTQLEMQAKEHEERLKQAQVEICELKKKPTELEEE----TNAKQQLQRKLQAALISRKEALKENKSLQEQLSSARDAV 1496
Cdd:TIGR02169  854 KEIENLNGKKEELEEELEELEAALRDLESRLGDLKKErdelEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEEL 933

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1497 ERLTKSLADVESQVsvqnqEKDAVLGKltiLQEERDKLIAEMDRFLLENQSLSGSCESLKLALGGLTEDKEKLMEELESV 1576
Cdd:TIGR02169  934 SEIEDPKGEDEEIP-----EEELSLED---VQAELQRVEEEIRALEPVNMLAIQEYEEVLKRLDELKEKRAKLEEERKAI 1005


                   .
gi 1720386946 1577 R 1577
Cdd:TIGR02169 1006 L 1006
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 2413-3154 5.04e-10

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 65.85  E-value: 5.04e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2413 NKRALEKTNQLTEALEAIKKEsfEQKAQLDSFVKSMSSLQDDRDR---IVSDYRQLEERHLSAILEKDQLIQDAAAENNK 2489
Cdd:TIGR02168  201 QLKSLERQAEKAERYKELKAE--LRELELALLVLRLEELREELEElqeELKEAEEELEELTAELQELEEKLEELRLEVSE 278

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2490 LKEEMRGLRSHMDDLNSENAKLDAELVQYRRDLNEViaikdSQQKQLLDAQLQQNKELRNEctkLEERLKGLEAEKQSLQ 2569
Cdd:TIGR02168  279 LEEEIEELQKELYALANEISRLEQQKQILRERLANL-----ERQLEELEAQLEELESKLDE---LAEELAELEEKLEELK 350

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2570 MSSDALQKEKQGLSKEIKNLQTQLTALQEEgtlgvyHAQLKAKEEELQRlnmALSSSQKRTADLEEELVCVQKEATRKVS 2649
Cdd:TIGR02168  351 EELESLEAELEELEAELEELESRLEELEEQ------LETLRSKVAQLEL---QIASLNNEIERLEARLERLEDRRERLQQ 421

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2650 EIEDQLKKELKHLHHDAGIMRNETETAEErvaELARDLVEMEQKLLTVTKENKDLMAQIQAFGRSMSSLQdSRDHATEEL 2729
Cdd:TIGR02168  422 EIEELLKKLEEAELKELQAELEELEEELE---ELQEELERLEEALEELREELEEAEQALDAAERELAQLQ-ARLDSLERL 497

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2730 GDLKKKYDASLKELAQLKEWqdssregdvLSQAAFPLSTSENVLSRLEKLNQQLTSKDEQLLhLSSELESSHNQVQSISK 2809
Cdd:TIGR02168  498 QENLEGFSEGVKALLKNQSG---------LSGILGVLSELISVDEGYEAAIEAALGGRLQAV-VVENLNAAKKAIAFLKQ 567

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2810 AmtslqNERDRLWSELEKFRKSE-EGKQRAAAPSAASSPAEVQSLKKAMSSLQNDRDRLL------KELKNLQQQYLQMS 2882
Cdd:TIGR02168  568 N-----ELGRVTFLPLDSIKGTEiQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLggvlvvDDLDNALELAKKLR 642

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2883 QEMT-------------------------------ELRPLKAQLQESQDQTKALQVMEEELRQENLSWQHELRQLRMEKN 2931
Cdd:TIGR02168  643 PGYRivtldgdlvrpggvitggsaktnssilerrrEIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELE 722

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2932 SWELHERRMKEQfLMAISDKDQQLGHLQSLLRELRSSSQAQILSTQYQR-QASPETSASLDGSQKLVYETELLRTQLNDS 3010
Cdd:TIGR02168  723 ELSRQISALRKD-LARLEAEVEQLEERIAQLSKELTELEAEIEELEERLeEAEEELAEAEAEIEELEAQIEQLKEELKAL 801

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 3011 LKEIHQKELRIQQLNSKFSQLLEEKNVLSTQLSDASQSLRENQHHYSNLFNHCAILEKEVQKLQAGP--LNTDVapgapq 3088
Cdd:TIGR02168  802 REALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIeeLESEL------ 875

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1720386946 3089 EKNGMHRKSEPETTGEEQPSFSEVQQQLCNTKQDLRELKKLLEEERDQRLTAENALSLAKEQIRRL 3154
Cdd:TIGR02168  876 EALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNL 941
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2391-2929 6.35e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 65.34  E-value: 6.35e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2391 EIKELENLLSQEEEENVALEEENKRALEKTNQLTEALEAIKKESFEQKAQLDSFVKSMSSLQDDRDRIVSDYRQLEERHL 2470
Cdd:COG1196    233 KLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRR 312

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2471 SAILEKDQL---IQDAAAENNKLKEEMRGLRSHMDDLNSENAKLDAELVQYRRDLNEVIAIKDSQQKQLLDAQLQQNKEL 2547
Cdd:COG1196    313 ELEERLEELeeeLAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEAL 392

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2548 RNEcTKLEERLKGLEAEKQSLQMSSDALQKEKQGLSKEIKNLQTQLTALQEEgtLGVYHAQLKAKEEELQRLNMALSSSQ 2627
Cdd:COG1196    393 RAA-AELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEA--LEEAAEEEAELEEEEEALLELLAELL 469

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2628 KRTADLEEELVCVQKEATRKVSEIEDQLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLTVTKENKDLMAQ 2707
Cdd:COG1196    470 EEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQ 549

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2708 IQAFGRSMSSLQDSRDHATEELGDLKKKYDASLKELAQLKEWQDSSREGDVLSQAAFPLSTSENVLSRLEKLNQQLTSKD 2787
Cdd:COG1196    550 NIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVA 629

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2788 EQLLHLSSELESSHNQVQSISKAMTSLQNERDRLwselekfRKSEEGKQRAAAPSAASSPAEVQSLKKAMSSLQNDRDRL 2867
Cdd:COG1196    630 ARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLT-------GGSRRELLAALLEAEAELEELAERLAEEELELEEALLAE 702

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1720386946 2868 LKELKNLQQQYLQMSQEMTELRPLKAQLQESQDQTKALQVMEEELRQENL-----------SWQHELRQLRME 2929
Cdd:COG1196    703 EEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEAleelpeppdleELERELERLERE 775
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 677-1230 8.95e-10

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 65.08  E-value: 8.95e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  677 HQGELERLKTQVLELETSLHTAE---ETYKRNLSEKVKEISSLTQLSEEVKESAEEARSTLA----AVTEERDQLLYQVK 749
Cdd:TIGR02168  307 LRERLANLERQLEELEAQLEELEsklDELAEELAELEEKLEELKEELESLEAELEELEAELEelesRLEELEEQLETLRS 386

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  750 ELDVL----AELRARVQELESSLAEAEKQRG-LDYESQRAQHNLLTEQIHSLSIEAKSKDVKIEALQRELDGVQLQFCEQ 824
Cdd:TIGR02168  387 KVAQLelqiASLNNEIERLEARLERLEDRRErLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEEL 466

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  825 GTQMKTLQSQLEAKEREVREGTER---LRDISQEMEGLSQALSQ----------------------KELEIAK------- 872
Cdd:TIGR02168  467 REELEEAEQALDAAERELAQLQARldsLERLQENLEGFSEGVKAllknqsglsgilgvlselisvdEGYEAAIeaalggr 546

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  873 MDQLLLEKQ----KDVETLQQ------------TIQEKDQQVTELSFSMTEKMVQL-------NEEKFSLGVE------- 922
Cdd:TIGR02168  547 LQAVVVENLnaakKAIAFLKQnelgrvtflpldSIKGTEIQGNDREILKNIEGFLGvakdlvkFDPKLRKALSyllggvl 626

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  923 -IKTLKEQLNLLSRTEEATK---EQVEESGAGSSLKLGHDE--SGQEGLQQELELLRKESEQRKRKLQAALINRKELLQK 996
Cdd:TIGR02168  627 vVDDLDNALELAKKLRPGYRivtLDGDLVRPGGVITGGSAKtnSSILERRREIEELEEKIEELEEKIAELEKALAELRKE 706

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  997 VSQLEEELAKVREDSRKEIPFGENERRKLEEDRENRDDPEEWGTSKWREVEaSLKQTISEKEVELEGIRRDLKEKTAAEE 1076
Cdd:TIGR02168  707 LEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELT-ELEAEIEELEERLEEAEEELAEAEAEIE 785

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1077 ELQAVVQRMTRDLQSKTKQIDLLQEEVTENQATIQKLVTGTMDAGNggSAAPVKETAASSPPGAGGEEHWKPELEGRILD 1156
Cdd:TIGR02168  786 ELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLER--RIAATERRLEDLEEQIEELSEDIESLAAEIEE 863

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1157 LEKDKTQLQKKLQEALIARKAI----------LKKAQEKEKQLKEELREQKDAYHHLQGQFHEQNKEKENIADQLRQLQC 1226
Cdd:TIGR02168  864 LEELIEELESELEALLNERASLeealallrseLEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQE 943


                   ....
gi 1720386946 1227 QARE 1230
Cdd:TIGR02168  944 RLSE 947
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1161-2023 1.04e-09

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 64.69  E-value: 1.04e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1161 KTQLQKKLQEALIARKAILKKAQEKEKQL---KEELREQKDAYHHLQGQFHEQNKEKENIADQLRQLQCQaresidrqlp 1237
Cdd:TIGR02168  199 ERQLKSLERQAEKAERYKELKAELRELELallVLRLEELREELEELQEELKEAEEELEELTAELQELEEK---------- 268

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1238 gtgqqepgppapsLEGISLEDTEpaSESDLHAAQpsppgetAALQATVSvaqiqaqlkemevekeelelKVSSIASELAK 1317
Cdd:TIGR02168  269 -------------LEELRLEVSE--LEEEIEELQ-------KELYALAN--------------------EISRLEQQKQI 306

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1318 KSEEVLLLQDQINEQGLEIQNLKAASVEAQAHTELLKQELESSQLKVAGL-EHLKTLQPELDALHKHMGQKEEEVNYLYG 1396
Cdd:TIGR02168  307 LRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLeAELEELEAELEELESRLEELEEQLETLRS 386

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1397 QLSEKEQTLTTVQTEMVEQERLIKALHTQLEMQAKEHEERLKQAQveicelKKKPTELEEETNAKQQLQRKLQAALISRK 1476
Cdd:TIGR02168  387 KVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLE------EAELKELQAELEELEEELEELQEELERLE 460

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1477 EALKENKSLQEQLSSARDAVERLTKSL-ADVESQVSVQNQEKDAVLGKLTILQeERDKLIAEMDRFLLENQSLSGSCESL 1555
Cdd:TIGR02168  461 EALEELREELEEAEQALDAAERELAQLqARLDSLERLQENLEGFSEGVKALLK-NQSGLSGILGVLSELISVDEGYEAAI 539

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1556 KLALGG-----LTEDKEKLMEELESVRSSKMAEST---EWQEKHKELQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQ 1627
Cdd:TIGR02168  540 EAALGGrlqavVVENLNAAKKAIAFLKQNELGRVTflpLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALS 619

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1628 ELYAKLRSTESdkrerekqLQDAEQEmeemkekmrkfAKSKQQKILELEEENDRLRAEAQPVGGTGESMEALLssnsSLK 1707
Cdd:TIGR02168  620 YLLGGVLVVDD--------LDNALEL-----------AKKLRPGYRIVTLDGDLVRPGGVITGGSAKTNSSIL----ERR 676

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1708 EELEKITLEHKTLSKEFEALMAEKDALSEETRNLKLQVEAqvLKQASLEATEKSDEPKDVIEEVTQavvgKSQERDALSD 1787
Cdd:TIGR02168  677 REIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQ--LRKELEELSRQISALRKDLARLEA----EVEQLEERIA 750

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1788 SAKLEDSEAIlmgdgakpgvsetfsshDDIKNYLQQLDQLKGRIAELEMEKQKDRELSQALENEKNALLTQISAKDSELK 1867
Cdd:TIGR02168  751 QLSKELTELE-----------------AEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELT 813

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1868 LLEEEVTKRTTLNQQIQEELCRVTKLKETAEEEKDDLEErlmnQLAELNGSIGNYYQDVTDAQIKNEQLESEMRNLQRCV 1947
Cdd:TIGR02168  814 LLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSE----DIESLAAEIEELEELIEELESELEALLNERASLEEAL 889

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1720386946 1948 SELEEEKQQLVKEKTKVESEIRKEYMEkiqgaqkgpankshAKELQELLREKQQEVKQLQKDCIRYLERISALEKT 2023
Cdd:TIGR02168  890 ALLRSELEELSEELRELESKRSELRRE--------------LEELREKLAQLELRLEGLEVRIDNLQERLSEEYSL 951
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 721-1470 1.05e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 64.70  E-value: 1.05e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  721 EEVKESAEEARSTLAAVTEERDQLLYQVKELDVLAELRARVQELESSL-------AEAEKQRGL-DYESQRAQHNLLTEQ 792
Cdd:TIGR02169  180 EEVEENIERLDLIIDEKRQQLERLRREREKAERYQALLKEKREYEGYEllkekeaLERQKEAIErQLASLEEELEKLTEE 259

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  793 IHSLSIEAKSKDVKIEALQREL----DGVQLQFCEQGTQMKTLQSQLEAK-----------EREVREGTERLRDISQEME 857
Cdd:TIGR02169  260 ISELEKRLEEIEQLLEELNKKIkdlgEEEQLRVKEKIGELEAEIASLERSiaekereledaEERLAKLEAEIDKLLAEIE 339

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  858 GLSQALSQKELEIAKMDQLLLEKQKDVETLQQTIQEKDQQVTELSfsmtEKMVQLNEEKFSLGVEIKTLKEQLNLLsrte 937
Cdd:TIGR02169  340 ELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETR----DELKDYREKLEKLKREINELKRELDRL---- 411

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  938 EATKEQVEESGAGSSLKLGHDESGQEGLQQELELLRKESEQRKRKLQAALINRKELLQKVSQLEEELAKV---REDSRKE 1014
Cdd:TIGR02169  412 QEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVekeLSKLQRE 491

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1015 IPFGENERRKLEEDRENRDDPEEWGTSKWREVEASLKQTISEKEvelegiRRDLKEKTAAEEELQAVV------------ 1082
Cdd:TIGR02169  492 LAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGE------RYATAIEVAAGNRLNNVVveddavakeaie 565

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1083 -------QRMT----RDLQSKTKQIDLLQEE----------------------------VTENQATIQKL---------- 1113
Cdd:TIGR02169  566 llkrrkaGRATflplNKMRDERRDLSILSEDgvigfavdlvefdpkyepafkyvfgdtlVVEDIEAARRLmgkyrmvtle 645

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1114 ---------VTGTMDAGNGGSAAPVKETAASsppgaggeehwkPELEGRILDLEKDKTQLQKKLQEALIARKAILKKAQE 1184
Cdd:TIGR02169  646 gelfeksgaMTGGSRAPRGGILFSRSEPAEL------------QRLRERLEGLKRELSSLQSELRRIENRLDELSQELSD 713

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1185 KEKQLKEELREQKDAyhhlqGQFHEQNKEK-ENIADQLRQLQcQARESIDRQLPgtgqqepgppapslegiSLEDTEPAS 1263
Cdd:TIGR02169  714 ASRKIGEIEKEIEQL-----EQEEEKLKERlEELEEDLSSLE-QEIENVKSELK-----------------ELEARIEEL 770

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1264 ESDLHAAQPsppgETAALQATVS---VAQIQAQLKEMEVEKEELELKVSSIASELAKKSEEVLLLQDqineqglEIQNLK 1340
Cdd:TIGR02169  771 EEDLHKLEE----ALNDLEARLShsrIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEK-------EIQELQ 839

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1341 AASVEAQAHTELLKQELESSQLKVAGLE-HLKTLQPELDALHKHMGQKEEEVNYLYGQLSEKEQTLTTVQTEMVEQERLI 1419
Cdd:TIGR02169  840 EQRIDLKEQIKSIEKEIENLNGKKEELEeELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRL 919

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1720386946 1420 KALHTQLEMQakehEERLKQAQVEICELKKKPTELEEETNAKQQLQRKLQA 1470
Cdd:TIGR02169  920 SELKAKLEAL----EEELSEIEDPKGEDEEIPEEELSLEDVQAELQRVEEE 966
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1990-2599 1.43e-09

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 63.89  E-value: 1.43e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1990 KELQELLREKQQEVKQLQKDCIRYLERISALEKTVKALEFVHTESQKDLDVTKGNLAQAVEHRKKAQAELSSFKILLDDT 2069
Cdd:TIGR04523   43 KTIKNELKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDLSKINSEIKNDKEQKNKL 122

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2070 QSEAArvladnlKLKKELQSNKESIKSQIKQ--KDEDLLRRLEQAEEKHRKEKKNMQEKLDALHREKAHVEETLAEIQVS 2147
Cdd:TIGR04523  123 EVELN-------KLEKQKKENKKNIDKFLTEikKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNK 195

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2148 LTR----------KDQEMKELQGSLDSTLAQLAAFTKSMSSLQDDRDRVIDEAKKWERRFGDAIQTKEEEvrlkeencia 2217
Cdd:TIGR04523  196 LLKlelllsnlkkKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKI---------- 265

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2218 lKDQLRQMAIHMEELKITVSRLEhdKEIWESKAQTELQHHQKAydklQEENKELTSQLEdarqlyhDSKNELTKLESELK 2297
Cdd:TIGR04523  266 -KKQLSEKQKELEQNNKKIKELE--KQLNQLKSEISDLNNQKE----QDWNKELKSELK-------NQEKKLEEIQNQIS 331

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2298 SLKDQTTDLNNSLEKCKEHENNLEGIIKQQEADIQNCKFSCEQLETDLAASRELTSRLHDEINAKEQKiISLLSGKEEAI 2377
Cdd:TIGR04523  332 QNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESK-IQNQEKLNQQK 410

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2378 QLAVEELHQQHSKEIKELENLLSQEEEENVALeeenKRALEKTNQLTEALEAIKKESFEQKAQLDSFVKSMSSLQDDRDR 2457
Cdd:TIGR04523  411 DEQIKKLQQEKELLEKEIERLKETIIKNNSEI----KDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQ 486

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2458 IVSDYRQLEERHLSAILEKDQLIQdaaaENNKLKEEMRGLRSHMDDLNSENAKLDAELVQYRRDLNEviaIKDSQQKQLL 2537
Cdd:TIGR04523  487 KQKELKSKEKELKKLNEEKKELEE----KVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNK---DDFELKKENL 559

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1720386946 2538 DAQLQQNKElrnECTKLEERLKGLEAEKQSLQMSSDALQKEKQGLSKEIKNLQTQLTALQEE 2599
Cdd:TIGR04523  560 EKEIDEKNK---EIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSLEKE 618
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1905-2475 1.98e-09

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 63.54  E-value: 1.98e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1905 EERLMNQLAELNGSIGNYYQDVTDAQIKNEQLESEMRNLQRCVSELEEEKQ---QLVKEKTKVESEIRKEyMEKIQGAQK 1981
Cdd:PRK03918   188 TENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEeieELEKELESLEGSKRKL-EEKIRELEE 266

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1982 GPANKshaKELQELLREKQQEVKQLQKDCIRYLERISALEKTVKALefvhtesqKDLDVTKGNLAQAVEHRKKAQAELSS 2061
Cdd:PRK03918   267 RIEEL---KKEIEELEEKVKELKELKEKAEEYIKLSEFYEEYLDEL--------REIEKRLSRLEEEINGIEERIKELEE 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2062 FKILLDDTQseaarvladnlKLKKELQSNKESIKSQIKQKDEdlLRRLEQAEEKHRKEKKN-----MQEKLDALHREKAH 2136
Cdd:PRK03918   336 KEERLEELK-----------KKLKELEKRLEELEERHELYEE--AKAKKEELERLKKRLTGltpekLEKELEELEKAKEE 402

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2137 VEETLAEIQVSLTRKDQEMKELQGSL-------------------DSTLAQLAAFTKSMSSLQDDRDRVIDEAKKWERRF 2197
Cdd:PRK03918   403 IEEEISKITARIGELKKEIKELKKAIeelkkakgkcpvcgrelteEHRKELLEEYTAELKRIEKELKEIEEKERKLRKEL 482

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2198 gdaiqTKEEEVRLKEENCIALKDQLRQMAIHMEELKitvsrlEHDKEIWESKAqTELQHHQKAYDKLQEENKELTSQLED 2277
Cdd:PRK03918   483 -----RELEKVLKKESELIKLKELAEQLKELEEKLK------KYNLEELEKKA-EEYEKLKEKLIKLKGEIKSLKKELEK 550

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2278 ARQLyhdsKNELTKLESELKSLKDQTTDLNNSLEKCK-EHENNLEGIIKQQEA------DIQNCKFSCEQLETDLAASRE 2350
Cdd:PRK03918   551 LEEL----KKKLAELEKKLDELEEELAELLKELEELGfESVEELEERLKELEPfyneylELKDAEKELEREEKELKKLEE 626

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2351 LTSRLHDEINAKEQKIISLLSGKEEAIQLAVEELHQQHSKEIKELENLLSQEEEENVALEEENKRALEKTNQLTEALEAI 2430
Cdd:PRK03918   627 ELDKAFEELAETEKRLEELRKELEELEKKYSEEEYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEER 706

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*
gi 1720386946 2431 KKesfeQKAQLDSFVKSMSSLQDDRDRIVSDYRQLEERHLSAILE 2475
Cdd:PRK03918   707 EK----AKKELEKLEKALERVEELREKVKKYKALLKERALSKVGE 747
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 324-1113 2.79e-09

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 63.15  E-value: 2.79e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  324 EKVELEVAERKLSFHNLQEEMHQLQGQLERAGQAQADLETQYSALQqrhkTEMEEKTACILSLQKNEQELQSACAALKEE 403
Cdd:TIGR02168  221 ELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELE----EKLEELRLEVSELEEEIEELQKELYALANE 296

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  404 NSKLLQEKhdqaAESAQAMRQLEDQLQQKSKEISQFVNKPNLQKNETASqtslpdvnnegdqavMEETVASLQKRVVELE 483
Cdd:TIGR02168  297 ISRLEQQK----QILRERLANLERQLEELEAQLEELESKLDELAEELAE---------------LEEKLEELKEELESLE 357

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  484 NEkgalllssgeLEELKAENEKLSSRITLLEAQNRAgeadgtvcevstagttllNRSDSSPEENGQAVLENTFSQKHKEL 563
Cdd:TIGR02168  358 AE----------LEELEAELEELESRLEELEEQLET------------------LRSKVAQLELQIASLNNEIERLEARL 409

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  564 SVLLVEMKEAQEEIAFLKSQLQGKRPEGDYEVLDRREVQLMESEGppSVTAGDVLCAPSDESSGPAAEEEQAGMKDRHRA 643
Cdd:TIGR02168  410 ERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQE--ELERLEEALEELREELEEAEQALDAAERELAQL 487

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  644 SEAGPLNDAGMELSSPKLDGVDKSLAVSHVCQCHQGELerlkTQVLELETSLHTAEETY---------KRNLSEKVKEIS 714
Cdd:TIGR02168  488 QARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVL----SELISVDEGYEAAIEAAlggrlqavvVENLNAAKKAIA 563

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  715 SLTQ---------------------LSEEVKESAEEARSTLAAVTEERDQL----------LYQVKELDVLAELRARVQE 763
Cdd:TIGR02168  564 FLKQnelgrvtflpldsikgteiqgNDREILKNIEGFLGVAKDLVKFDPKLrkalsyllggVLVVDDLDNALELAKKLRP 643

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  764 LES---------------SLAEAEKQRGLDYESQ-----RAQHNLLTEQIHSLSIEAKSKDVKIEALQRELDGVQLQFCE 823
Cdd:TIGR02168  644 GYRivtldgdlvrpggviTGGSAKTNSSILERRReieelEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEE 723

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  824 QGTQMKTLQSQLEAKEREVREGTERLRDISQEMEGLSQALSQKELEIAKMDQLLLEKQKDVETLQQTIQEKDQQVTELSF 903
Cdd:TIGR02168  724 LSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALRE 803

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  904 SMTEKMVQLNEEKFSLGVEIKTLKEQLNLLSRTE------EATKEQVEESGAGSSLKLGHDESGQEGLQQELELLRKESE 977
Cdd:TIGR02168  804 ALDELRAELTLLNEEAANLRERLESLERRIAATErrledlEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERA 883

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  978 QRKRKLQAALINRKELLQKVSQLEEELAKVREDSRKEIPFGENERRKLEEDRENRDDPEEWGTSKWREVEASLKQTISEK 1057
Cdd:TIGR02168  884 SLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKI 963

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1720386946 1058 EVELEGIRRDLKEKT-----------AAEEELQAVVQRmtrdLQSKTKQIDLLQEEVTENQATIQKL 1113
Cdd:TIGR02168  964 EDDEEEARRRLKRLEnkikelgpvnlAAIEEYEELKER----YDFLTAQKEDLTEAKETLEEAIEEI 1026
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 2085-2662 4.06e-09

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 62.73  E-value: 4.06e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2085 KELQSNKESIKSQIKQKdEDLLRRLEQAEEKHRKEKKNMQEKLdalhrekahveETLAEIQVSLTRKDQEMKELQGSLDS 2164
Cdd:TIGR04523   36 KQLEKKLKTIKNELKNK-EKELKNLDKNLNKDEEKINNSNNKI-----------KILEQQIKDLNDKLKKNKDKINKLNS 103

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2165 TLAQLAAFTKSMSSLQDDRDRVIDEAKKWERRFGDAIQTKEEEVRLKEENCIALKDQLRQMAIHMEELKITVSRLEHDKE 2244
Cdd:TIGR04523  104 DLSKINSEIKNDKEQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKL 183

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2245 IWESK-AQTELQHHQKAY-----DKLQEENKELTSQLEDARQLYHDSKNELTKLESELKSLKDQTTDLNNSLEKCKEHEN 2318
Cdd:TIGR04523  184 NIQKNiDKIKNKLLKLELllsnlKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQN 263

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2319 NLEGIIKQQEADIQNCKFSCEQLETDLaasRELTSRLHDEINAKEQKIISLLSGKEEAIQLAVEELHQQHSKEIKELENL 2398
Cdd:TIGR04523  264 KIKKQLSEKQKELEQNNKKIKELEKQL---NQLKSEISDLNNQKEQDWNKELKSELKNQEKKLEEIQNQISQNNKIISQL 340

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2399 LSQEEEENVALEEENKRALEKTNQLTE---ALEAIKKESFEQKAQLDSFVKSMSSLQDDRDRIVSDYRQLEERHLSAILE 2475
Cdd:TIGR04523  341 NEQISQLKKELTNSESENSEKQRELEEkqnEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQE 420

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2476 KDQL---IQDAAAENNKLKEEMRGLRSHMDDLNSENAKLDA---ELVQYRRDLNEVIAIKDS---QQKQLLDAQLQQNKE 2546
Cdd:TIGR04523  421 KELLekeIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNtreSLETQLKVLSRSINKIKQnleQKQKELKSKEKELKK 500

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2547 LRNECTKLEERLKGLEAEKQSLQMSSDALQKEKQGLSKEIKNLQTQLTALQEEGTLGVYHAQLKAKEEELQRLNMALSSS 2626
Cdd:TIGR04523  501 LNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDFELKKENLEKEIDEKNKEIEELKQTQKSL 580

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|..
gi 1720386946 2627 QKRTADLEEELVCVQKEATRKVSEIE------DQLKKELKHL 2662
Cdd:TIGR04523  581 KKKQEEKQELIDQKEKEKKDLIKEIEekekkiSSLEKELEKA 622
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2269-2874 5.16e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 62.26  E-value: 5.16e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2269 KELTSQLEDARQlYHDSKNELTKLESELKSLKDQttdlnnslekckehenNLEGIIKQQEADIQNCKFSCEQLETDLAAS 2348
Cdd:COG1196    203 EPLERQAEKAER-YRELKEELKELEAELLLLKLR----------------ELEAELEELEAELEELEAELEELEAELAEL 265

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2349 RELTSRLHDEINAKEQKIiSLLSGKEEAIQLAVEELHQQHSKEIKELENLLSQEEEENVALEEENKRALEKTNQLTEALE 2428
Cdd:COG1196    266 EAELEELRLELEELELEL-EEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEE 344

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2429 AIKkesfEQKAQLDSFVKSMSSLQDDRDRIVSDYRQLEERHLSAILEKDQLIQDAAAENNKLKEemrgLRSHMDDLNSEN 2508
Cdd:COG1196    345 ELE----EAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEE----LEEAEEALLERL 416

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2509 AKLDAELVQYRRDLNEVIAIKDSQQKQLLDAQLQQNKELRNECTKLEERLKGLEAEKQSLQMSSDALQKEKQGLSKEikN 2588
Cdd:COG1196    417 ERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARL--L 494

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2589 LQTQLTALQEEGTLGVYHAQLKAKEEEL-QRLNMALSSSQKRTADLEEELVCVQKEATRKVSEIEDQLKKELKHlhHDAG 2667
Cdd:COG1196    495 LLLEAEADYEGFLEGVKAALLLAGLRGLaGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKA--AKAG 572

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2668 IMRNETETAEERVAELARDLVEMEQKLLTVTKENKDLMAQIQAFGRSMSSLQDSRDHATEELGDLKKKYDASLKELAQLK 2747
Cdd:COG1196    573 RATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLE 652

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2748 EWQDSSREGDVLSQAAFPLSTSENVLSRLEKLNQQLTSKDEQLLHLSSELESSHNQVQSISKAMTSLQNERDRLWSELEK 2827
Cdd:COG1196    653 GEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEA 732

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*..
gi 1720386946 2828 FRKSEEGKQRAAAPSAASSPAEVQSLKKAMSSLQNDRDRLLKELKNL 2874
Cdd:COG1196    733 EREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEAL 779
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 728-1214 6.46e-09

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 62.16  E-value: 6.46e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  728 EEARSTLAAVTEERDQLLYQVKELDVLAELRARVQELESSLAEAEKQRGLDYESQ-RAQHNLLTEQIHSLSIEAKSKDVK 806
Cdd:pfam12128  237 MKIRPEFTKLQQEFNTLESAELRLSHLHFGYKSDETLIASRQEERQETSAELNQLlRTLDDQWKEKRDELNGELSAADAA 316

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  807 IEALQRELDGVQ---LQFCEQG--------TQMKTLQSQLEAKEREVREGTERLRDISQEMEGLSQALSQK-ELEIAKMD 874
Cdd:pfam12128  317 VAKDRSELEALEdqhGAFLDADietaaadqEQLPSWQSELENLEERLKALTGKHQDVTAKYNRRRSKIKEQnNRDIAGIK 396

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  875 QLLlEKQKDVETLQQTIQEKD--QQVTELSFSMTEKMVQLNEEKFSLGVEIKTLKEQLNLLSRTEE--ATKEQVEESGAG 950
Cdd:pfam12128  397 DKL-AKIREARDRQLAVAEDDlqALESELREQLEAGKLEFNEEEYRLKSRLGELKLRLNQATATPEllLQLENFDERIER 475

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  951 SSLKLGHDESGQEGLQQELELLRKESEQRKRKLQAALINRKELLQKVSQLEEEL----AKVREDSRKEIP-FGENERRKL 1025
Cdd:pfam12128  476 AREEQEAANAEVERLQSELRQARKRRDQASEALRQASRRLEERQSALDELELQLfpqaGTLLHFLRKEAPdWEQSIGKVI 555

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1026 EEDRENRDD--PEEWgtskwrevEASLKQTISEKEVELEGIRRDLKEKTAAEEELQAVVQRMTRDLQSKTKQIDLLQEEV 1103
Cdd:pfam12128  556 SPELLHRTDldPEVW--------DGSVGGELNLYGVKLDLKRIDVPEWAASEEELRERLDKAEEALQSAREKQAAAEEQL 627

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1104 TENQATIQKLVTGTMDAGNGGSAApvketaassppgaggeehwkpelEGRILDLEKDKTQLQKKLQEALIARKA-ILKKA 1182
Cdd:pfam12128  628 VQANGELEKASREETFARTALKNA-----------------------RLDLRRLFDEKQSEKDKKNKALAERKDsANERL 684

                          490       500       510
                   ....*....|....*....|....*....|..
gi 1720386946 1183 QEKEKQLKEELREQKDAYHHLQGQFHEQNKEK 1214
Cdd:pfam12128  685 NSLEAQLKQLDKKHQAWLEEQKEQKREARTEK 716
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1589-2185 7.42e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 61.88  E-value: 7.42e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1589 EKHKELQKEYEVLlqsyenvsnEAERIQHVVESVRQEKQELyaklrSTESDKREREKQLQDAEQEMEEMKEKMRKfaKSK 1668
Cdd:COG1196    213 ERYRELKEELKEL---------EAELLLLKLRELEAELEEL-----EAELEELEAELEELEAELAELEAELEELR--LEL 276

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1669 QQKILELEEENDRLRAEAQPVGGTGESMEALLSSNSSLKEELEKITLEHKTLSKEFEALMAEKDALSEETRNLKLQVEAQ 1748
Cdd:COG1196    277 EELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEA 356

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1749 VLKQASLEATEKSDEpKDVIEEVTQAVVGKSQERDALSDSAKLEdseailmgdgakpgvsetfsshDDIKNYLQQLDQLK 1828
Cdd:COG1196    357 EAELAEAEEALLEAE-AELAEAEEELEELAEELLEALRAAAELA----------------------AQLEELEEAEEALL 413

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1829 GRIAELEMEKQKDRELSQALENEKNALLTQISAKDSELKLLEEEVTKRTTLNQQIQEELCRVTKLKETAEEEKDDLEERL 1908
Cdd:COG1196    414 ERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARL 493

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1909 mNQLAELNGSIGNYYQDVTDAQIKNEQ--LESEMRNLQRCVSELEEE---------KQQLVKEKTKVESEIRKEYMEKIQ 1977
Cdd:COG1196    494 -LLLLEAEADYEGFLEGVKAALLLAGLrgLAGAVAVLIGVEAAYEAAleaalaaalQNIVVEDDEVAAAAIEYLKAAKAG 572

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1978 GAQKGPANKSHAKELQELLREKQQEVKQLqkDCIRYLERISALEKTVKALEFVHTESQKDLDVTKGNLAQAVEHRKKAQA 2057
Cdd:COG1196    573 RATFLPLDKIRARAALAAALARGAIGAAV--DLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVT 650

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2058 ELSSFKILLDDTQSEAARVLADNLKLKKELQSNKESIKSQIKQKDEDLLRRLEQAEEKHRKEKKNMQEKLDALHREKAHV 2137
Cdd:COG1196    651 LEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQL 730

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*...
gi 1720386946 2138 EETLAEIQVSLTRKDQEMKELQGSLDSTLAQLAAFTKSMSSLQDDRDR 2185
Cdd:COG1196    731 EAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEA 778
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1152-1919 7.61e-09

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 62.00  E-value: 7.61e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1152 GRILDLEKDKTQLQKKLQEALIARKAILKKAQEKEKQLKE---ELREQKDAYHHLQGQFHEQNKEKENIADQLRQLQCQA 1228
Cdd:TIGR02168  232 LRLEELREELEELQEELKEAEEELEELTAELQELEEKLEElrlEVSELEEEIEELQKELYALANEISRLEQQKQILRERL 311

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1229 RESIDRQLPGTGQQEPGPPAPSLEGISLEDTEPASEsdlhaaqpsppgetaalQATVSVAQIQAQLKEMEVEKEELELKV 1308
Cdd:TIGR02168  312 ANLERQLEELEAQLEELESKLDELAEELAELEEKLE-----------------ELKEELESLEAELEELEAELEELESRL 374

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1309 SSIASELAKKSEEVLLLQDQINEQGLEIQNLKAASVEAQAHTELLKQELEsSQLKVAGLEHLKTLQPELDALHKHMGQKE 1388
Cdd:TIGR02168  375 EELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIE-ELLKKLEEAELKELQAELEELEEELEELQ 453

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1389 EEVNYLYGQLSEKEQTLTTVQTEMVEQERLIKALHTQLEMqAKEHEERLKQAQVEICELKKKPTELEEETNAKQQ----- 1463
Cdd:TIGR02168  454 EELERLEEALEELREELEEAEQALDAAERELAQLQARLDS-LERLQENLEGFSEGVKALLKNQSGLSGILGVLSElisvd 532

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1464 ----------LQRKLQAALISRKEALKENKSLQEQLSSARDAVERLTkSLADVESQVSVQN--QEKDAVLGKLTILQEER 1531
Cdd:TIGR02168  533 egyeaaieaaLGGRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLD-SIKGTEIQGNDREilKNIEGFLGVAKDLVKFD 611

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1532 DKLIAEMDRFLlenqSLSGSCESLKLALGGLTEDKEKLM-------------------EELESVRSSKMAESTEWQEKHK 1592
Cdd:TIGR02168  612 PKLRKALSYLL----GGVLVVDDLDNALELAKKLRPGYRivtldgdlvrpggvitggsAKTNSSILERRREIEELEEKIE 687

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1593 ELQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQELYAKLRSTESDKREREKQLQDAEQEMEEMKEKMRKFAKSKQQKI 1672
Cdd:TIGR02168  688 ELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELE 767

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1673 LELEEENDRLRAEAQPVGGTGESMEALLSSNSSLKEELEKITLEHKTLSKEFEAL-----MAEKDALSEETRNLKLQVEA 1747
Cdd:TIGR02168  768 ERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLrerleSLERRIAATERRLEDLEEQI 847

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1748 QVLKQASLEATEKSDEPKDVIEEVTQAVVGKSQERDALSDSAKLEDSEAILMGDGAKpgvsetfSSHDDIKNYLQQLDQL 1827
Cdd:TIGR02168  848 EELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELR-------ELESKRSELRRELEEL 920

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1828 KGRIAELEMEKQKdrelsqaLENEKNALLTQISAKDS-ELKLLEEEVTKRTTLNQQIQEELCRVT-KLKE------TAEE 1899
Cdd:TIGR02168  921 REKLAQLELRLEG-------LEVRIDNLQERLSEEYSlTLEEAEALENKIEDDEEEARRRLKRLEnKIKElgpvnlAAIE 993

                          810       820
                   ....*....|....*....|...
gi 1720386946 1900 EKDDLEER---LMNQLAELNGSI 1919
Cdd:TIGR02168  994 EYEELKERydfLTAQKEDLTEAK 1016
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 924-1629 1.17e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 61.11  E-value: 1.17e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  924 KTLKEQLNLLSRTEEATK-EQVEESGAGSSLKLGHDESGQEGLQQELELLRKESEQRKRKLQAALINRKELLQKVSQLEE 1002
Cdd:COG1196    216 RELKEELKELEAELLLLKlRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLA 295

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1003 ELAKVREDSRKEipfgeNERRKLEEDRENRDDPEEwgtSKWREVEASLKQTISEKEVELEGIRRDLKEKTAAEEELQAVV 1082
Cdd:COG1196    296 ELARLEQDIARL-----EERRRELEERLEELEEEL---AELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEAL 367

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1083 QRMTRDLQSKTKQIDLLQEEVTENQATIQklvtgtmdagnggsaapvketaassppgaggeehwkpELEGRILDLEKDKT 1162
Cdd:COG1196    368 LEAEAELAEAEEELEELAEELLEALRAAA-------------------------------------ELAAQLEELEEAEE 410

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1163 QLQKKLQEALIARKAILKKAQEKEKQLKEELREQKDAYHHLQGQFHEQNKEKENIADQLRQLQCQARESIDRQLPgtgqq 1242
Cdd:COG1196    411 ALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEE----- 485

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1243 epgppapslegislEDTEPASESDLHAAQPSPPGETAALQATVSVAQIQAQLKEMEVEKEELELKVSSIASELAkkseev 1322
Cdd:COG1196    486 --------------LAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALA------ 545

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1323 lllqdqineqGLEIQNLKAASVEAQAHTELLKQELESsqlKVAGLEHLKTLQPELDALHKHMGQKEEEVNYLYGQLSEKE 1402
Cdd:COG1196    546 ----------AALQNIVVEDDEVAAAAIEYLKAAKAG---RATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREAD 612

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1403 QTLTTVQTEMVEQERLIKALHT-QLEMQAKEHEERLKQAQVEICELKKKPTELEEETNAKQQLQRKLQAALISRKEAlKE 1481
Cdd:COG1196    613 ARYYVLGDTLLGRTLVAARLEAaLRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLA-EE 691

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1482 NKSLQEQLSSARDAVERLTKSLADVESQVSVQNQEKDAVLGKLTILQEERDKLIAEMDRFLLENQSLSGSCESLKLALGG 1561
Cdd:COG1196    692 ELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELER 771

                          650       660       670       680       690       700
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1720386946 1562 LTEDkeklMEELESVRSskMAEstewqEKHKELQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQEL 1629
Cdd:COG1196    772 LERE----IEALGPVNL--LAI-----EEYEELEERYDFLSEQREDLEEARETLEEAIEEIDRETRER 828
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1311-1835 6.08e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 58.79  E-value: 6.08e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1311 IASELAKKSEEVLLLQDQINEQGLEIQNLKAASVEAQAHTELLKQELESSQlkvAGLEHLKTLQPELDALHKHMGQKEEE 1390
Cdd:COG1196    251 LEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLE---QDIARLEERRRELEERLEELEEELAE 327

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1391 VNYLYGQLSEKEQTLTTVQTEMVEQERLIKALHTQLEMQAKEHEERLKQAQVEICELKKkptELEEETNAKQQLQRKLQA 1470
Cdd:COG1196    328 LEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAE---ELLEALRAAAELAAQLEE 404

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1471 ALISRKEALKENKSLQEQLSSARDAVERLTKSLADVESQVSVQNQEKDAVLGKLTILQEERDKLIAEMDRFLLENQSLSG 1550
Cdd:COG1196    405 LEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLE 484

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1551 SCESLKLALGGLTEDKEKLMEELESVRSSKMAEST--------EWQEKHKELQKEYEVLLQSY------ENVSNEAERIQ 1616
Cdd:COG1196    485 ELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLrglagavaVLIGVEAAYEAALEAALAAAlqnivvEDDEVAAAAIE 564

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1617 HVVESV--RQEKQELYAKLRSTESDKREREKQLQDAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEAQPVGGTGE 1694
Cdd:COG1196    565 YLKAAKagRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAG 644

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1695 SMEALLSSNSSLKEELEKITLEHKTLSKEFEALMAEKDALSEETRNLKLQVEAQVLKQASLEATEKSDEPKDVIEEVTQA 1774
Cdd:COG1196    645 RLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEE 724

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1720386946 1775 VVGKSQERDALSDSAKLEDSEAILMGDGAKPGVSEtfsshDDIKNYLQQLDQLKGRIAELE 1835
Cdd:COG1196    725 ALEEQLEAEREELLEELLEEEELLEEEALEELPEP-----PDLEELERELERLEREIEALG 780
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 51-370 7.44e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 58.41  E-value: 7.44e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946   51 EDALHRLAEAEKLVVELKDIISQKDVQLqqkdEALQEEKKAAEN----KIKKIKLHAKAKIMSLNKHMEEIKTQGGAAlp 126
Cdd:COG1196    175 EEAERKLEATEENLERLEDILGELERQL----EPLERQAEKAERyrelKEELKELEAELLLLKLRELEAELEELEAEL-- 248

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  127 pEAQAEELSKHNKSSTEEEMEIEKIKHELQEKEKLISSLQAQLdqSEQASQLDKSSAEMEDFVLMKQQLQEKEELISTLQ 206
Cdd:COG1196    249 -EELEAELEELEAELAELEAELEELRLELEELELELEEAQAEE--YELLAELARLEQDIARLEERRRELEERLEELEEEL 325

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  207 TQLSQTQAEQAAQVVREKDARFETQVRLHEDElLQLVTQSDVETEMQQKLRVMQRKLEEHEEALLGRAQVVDLLQKELTS 286
Cdd:COG1196    326 AELEEELEELEEELEELEEELEEAEEELEEAE-AELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEE 404

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  287 AEQRNQVLSQQLQLLEAEHNTLkntmETERQESKTLMEKVELEVAERKLSFHNLQEEMHQLQGQLERAGQAQADLETQYS 366
Cdd:COG1196    405 LEEAEEALLERLERLEEELEEL----EEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALA 480


                   ....
gi 1720386946  367 ALQQ 370
Cdd:COG1196    481 ELLE 484
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1817-2588 1.25e-07

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 58.06  E-value: 1.25e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1817 IKNYLQQLDQLKGRIAELEMEKQKDRELSQALENEKNALLTQISAKDSELKLLEEEVTKRttlnQQIQEELCRVTKLKET 1896
Cdd:pfam02463  281 KKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEEL----EKELKELEIKREAEEE 356

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1897 AEEEKDDLEERLMNQLAELNGSIGNYYQDVTDAQIKNEQLESEMRNLQRCVS---ELEEEKQQLVKEKTKVESEIRKEYM 1973
Cdd:pfam02463  357 EEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQlllELARQLEDLLKEEKKEELEILEEEE 436

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1974 EKIQGAQKGPANKSHAKELQELLREKQQEVKQLQKDcirylerisalektvkalefvhtesqkdldvtKGNLAQAVEHRK 2053
Cdd:pfam02463  437 ESIELKQGKLTEEKEELEKQELKLLKDELELKKSED--------------------------------LLKETQLVKLQE 484

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2054 KAQAELSSFKILLDDTQSEAARVLADNLKLKKELQSNKESIKSQIKQKDEDLLRRLEQAEEKHRKEKKNMQEKLDALHRE 2133
Cdd:pfam02463  485 QLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQ 564

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2134 KAHVEETLAEIQVSLTRKDQEMKELQGSLDSTLAQLAAfTKSMSSLQDDRDRVIDEAKKWERRFGDAIQTKEEEVRLKEE 2213
Cdd:pfam02463  565 KLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPI-LNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKA 643

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2214 NCIALKDQLRQMAIHMEELKITVSRLEHDKEIWESKAQTELQHHQKAYDKLQEENKELTSQLEDARQLYHDSKNELTKLE 2293
Cdd:pfam02463  644 KESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELL 723

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2294 SELKSLKDQTTDLNNSLEKCKEHENNLEGIIKQQEADIQNCKFSCEQLETDLAASReltsRLHDEINAKEQKIISLLSGK 2373
Cdd:pfam02463  724 ADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEE----REKTEKLKVEEEKEEKLKAQ 799

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2374 EEAIQLAVEELHQQHSKEIKELENLLSQEEEENVALEEENKRALEKTNQLTEALEAIKKESFEQKAQLDSFVKSMSSLQD 2453
Cdd:pfam02463  800 EEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEEL 879

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2454 DRDRIVsDYRQLEERHLSAILEKDQLIQDAAAENNKLKEEMRGLRSHMDDLNSENAKLDAELVQYRRDLNEVIAIKDSQQ 2533
Cdd:pfam02463  880 EEQKLK-DELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEE 958

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1720386946 2534 KQLLDAQLQQNKELRN-------ECTKLEERLKGLEAEKQSLQMSSDALQKEKQGLSKEIKN 2588
Cdd:pfam02463  959 EERNKRLLLAKEELGKvnlmaieEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQRLK 1020
PTZ00121 PTZ00121
MAEBL; Provisional
 959-1687 2.91e-07

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 56.69  E-value: 2.91e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  959 ESGQEGLQQELELLRKESEQRKRKLQAALINRKELLQKVSQLEEElAKVREDSRKEIPFGENERRKLEEDRENRDDPEEW 1038
Cdd:PTZ00121  1101 EEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEA-RKAEDAKRVEIARKAEDARKAEEARKAEDAKKAE 1179

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1039 GTSKWREVEASLKQTISEKEVELEGIRRDLKEKTAAE---EELQAVVQRMTRDLQSKTKQIDLLQEEVTENQATIQKLVT 1115
Cdd:PTZ00121  1180 AARKAEEVRKAEELRKAEDARKAEAARKAEEERKAEEarkAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEE 1259

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1116 GTMDAGNGGSAAPVKETAASSPPGAGGEEHWKPElEGRILDLEKDKTQLQKKLQEALIARKAiLKKAQEKEKQ---LKEE 1192
Cdd:PTZ00121  1260 ARMAHFARRQAAIKAEEARKADELKKAEEKKKAD-EAKKAEEKKKADEAKKKAEEAKKADEA-KKKAEEAKKKadaAKKK 1337

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1193 LREQKDAYHHLQGQFHEQNKEKENIADQLRQLQCQARESIDRQLPGTGQQEPGPPAPSLEGISLEDTEPASESDLHAAQP 1272
Cdd:PTZ00121  1338 AEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAK 1417

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1273 SPPGETAALQATVSVAQiqaqlkemeveKEELELKVSSIASELAKKSEEvlllqdqineqGLEIQNLKAASVEAQAHTEL 1352
Cdd:PTZ00121  1418 KKADEAKKKAEEKKKAD-----------EAKKKAEEAKKADEAKKKAEE-----------AKKAEEAKKKAEEAKKADEA 1475

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1353 LKQELESSQlkvagLEHLKTLQPELDALHKHMGQKEEEVNYLyGQLSEKEQTLTTVQTEMVEQERliKALHTQLEMQAKE 1432
Cdd:PTZ00121  1476 KKKAEEAKK-----ADEAKKKAEEAKKKADEAKKAAEAKKKA-DEAKKAEEAKKADEAKKAEEAK--KADEAKKAEEKKK 1547

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1433 HEERLKQAQVEICELKKKPTELEEETNAKQQLQRKLQAALISRKEALKENKSLQEQLSSARDAVERLTKSLADVESQVSV 1512
Cdd:PTZ00121  1548 ADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKK 1627

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1513 QNQEKDAVLGKLTILQEERDKliAEMDRFLLENQSLSGSCESLKLALGGLTEDKEKLMEELESVRSSKMAESTEWQEKHK 1592
Cdd:PTZ00121  1628 AEEEKKKVEQLKKKEAEEKKK--AEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAE 1705

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1593 ELQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQELYAKLRSTESDKREREKQLQDAEQEMEEMKEKMRKFAKSKQQki 1672
Cdd:PTZ00121  1706 ELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEE-- 1783

                          730
                   ....*....|....*
gi 1720386946 1673 lELEEENDRLRAEAQ 1687
Cdd:PTZ00121  1784 -ELDEEDEKRRMEVD 1797
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1932-2663 3.96e-07

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 56.13  E-value: 3.96e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1932 KNEQLESEMRNLQRCVSELEEEKQQLVKEKTKVESEIRKEY-MEKIQGAQKGPANKSHAKELQELLREKQQEVKQLQKDC 2010
Cdd:pfam02463  174 ALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQlKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEI 253

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2011 IRYLERISALEKTVKALEFVHTESQKDLDVTKGNLAQAVEHRKKAQAELSSFKILLDDTQSEAARVLADNLKLKKELQSN 2090
Cdd:pfam02463  254 ESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKE 333

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2091 KESIKSQIKQKDEDLLRRLEQAEEKhrkekknmqEKLDALHREKAHVEETLAEIQvsltRKDQEMKELQGSLDSTLAQLA 2170
Cdd:pfam02463  334 KEEIEELEKELKELEIKREAEEEEE---------EELEKLQEKLEQLEEELLAKK----KLESERLSSAAKLKEEELELK 400

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2171 AFTKSMSSLQDDRDRVIDEAKKWERRFGDAIQTKEEEVRLKEENCIALKDQLRQMAIHMEELKITVSRLEHDKEIWESKA 2250
Cdd:pfam02463  401 SEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLV 480

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2251 QTELQHHQKAYDKLQEENKELTSQLEDARQLYHDSKNELTKLESELKSLKdqTTDLNNSLEKCKEHENNLEGIIKQQEAD 2330
Cdd:pfam02463  481 KLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGR--LGDLGVAVENYKVAISTAVIVEVSATAD 558

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2331 IQNCKFSCEQLETDLAASRELTSRLHDEINAKEQKIISL-------LSGKEEAIQLAVEELHQQHSKEIKELENLLSQEE 2403
Cdd:pfam02463  559 EVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLeidpilnLAQLDKATLEADEDDKRAKVVEGILKDTELTKLK 638

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2404 EENVALEEENKRALEKTNQLTEALEAIKKESFEQKAQLDSFVKSMSSLQDdrdrivsdyrQLEERHLSAILEKDQLIQDA 2483
Cdd:pfam02463  639 ESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESE----------LAKEEILRRQLEIKKKEQRE 708

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2484 AAENNKLKEEMRGLRSHMDDLNSENAKLDAELVQYRRDLN----EVIAIKDSQQKQLLDAQLQQNKELRNECTKLEERLK 2559
Cdd:pfam02463  709 KEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEeeeeEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKV 788

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2560 GLEAEKQSLQMSSDALQKEKQGLSKEIKNLQTQLTALQEEGTLGVYHAQLKAKEEELQRLNMALSSSQKRTADLEEELVC 2639
Cdd:pfam02463  789 EEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEEL 868

                          730       740
                   ....*....|....*....|....
gi 1720386946 2640 VQKEATRKVSEIEDQLKKELKHLH 2663
Cdd:pfam02463  869 LQELLLKEEELEEQKLKDELESKE 892
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
2453-2732 6.86e-07

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 55.31  E-value: 6.86e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2453 DDRDRIVSDYrQLEERHLSAILEKDQLIQDAAAENNKLKEEMRGLRSHMDDLNSENAKLdAELVQYRRDLNEViaikDSQ 2532
Cdd:COG4913    593 DDRRRIRSRY-VLGFDNRAKLAALEAELAELEEELAEAEERLEALEAELDALQERREAL-QRLAEYSWDEIDV----ASA 666

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2533 QKQL--LDAQLQQNKELRNECTKLEERLKGLEAEKQSLQMSSDALQKEKQGLSKEIKNLQTQLTALQ---EEGTLGVYHA 2607
Cdd:COG4913    667 EREIaeLEAELERLDASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQdrlEAAEDLARLE 746

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2608 QLKAKEEELQRLNMALSSSQKRtADLEEELVCVQKEATRKVSEIEDQLKKELKHLHHDAGIMRNETETAEERVAELAR-- 2685
Cdd:COG4913    747 LRALLEERFAAALGDAVERELR-ENLEERIDALRARLNRAEEELERAMRAFNREWPAETADLDADLESLPEYLALLDRle 825

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2686 --DLVEMEQKLLT-VTKENKDLMAQIQafgrsmSSLQDSRDHATEELGDL 2732
Cdd:COG4913    826 edGLPEYEERFKElLNENSIEFVADLL------SKLRRAIREIKERIDPL 869
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1815-2448 1.06e-06

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 54.64  E-value: 1.06e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1815 DDIKNYLQQLDQLKGRIAELEMEKQKDRELSQALENEKNALLTQISAKDSELKLLEEEVTKRTTLNQQIQEELCRVTKLK 1894
Cdd:TIGR04523   89 DKLKKNKDKINKLNSDLSKINSEIKNDKEQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQK 168

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1895 ETAEEEKDDLEERLMNQLAELNGSIGNYYQDVTDAQI------KNEQLESEMRNLQRCVSELEEEKQQLVKEKTKVESEI 1968
Cdd:TIGR04523  169 EELENELNLLEKEKLNIQKNIDKIKNKLLKLELLLSNlkkkiqKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEI 248

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1969 rkeymekiqgaqkgpanKSHAKELQELLREKQQEVKQLQkdcirylerisalektvkalefvhtESQKDLDVTKGNLAQA 2048
Cdd:TIGR04523  249 -----------------SNTQTQLNQLKDEQNKIKKQLS-------------------------EKQKELEQNNKKIKEL 286

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2049 VEHRKKAQAELSsfkillddtqseaarvladNLKLKKELQSNKEsIKSQIKQKDEDlLRRLEQAEEKHRKEKKNMQEKLD 2128
Cdd:TIGR04523  287 EKQLNQLKSEIS-------------------DLNNQKEQDWNKE-LKSELKNQEKK-LEEIQNQISQNNKIISQLNEQIS 345

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2129 ALHREKAHVEETLAEIQVSLTRKDQEMKELQGSLDSTLAQLAAFTKSMSSLQddrdRVIDEAKKWERRFGDAIQTKEEEV 2208
Cdd:TIGR04523  346 QLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLE----SKIQNQEKLNQQKDEQIKKLQQEK 421

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2209 RLKEENCIALKDQLRQMAIHMEELKITvsrlEHDKEIWESKAQTELQHHQKAYDKLQEENKELTSQLEDARQLYHDSKNE 2288
Cdd:TIGR04523  422 ELLEKEIERLKETIIKNNSEIKDLTNQ----DSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKE 497

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2289 LTKLESELKSLKDQTTDLNNSLEKCKEHENNLEGIIKQQEADIQNCKFSCEQLETDLAasrelTSRLHDEINAKEQKIIS 2368
Cdd:TIGR04523  498 LKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDFELK-----KENLEKEIDEKNKEIEE 572

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2369 LLSGKE--EAIQLAVEELHQQHSKEIKELENLLSQEEEENVALeeenKRALEKTNQLTEALEAIKKESFEQKAQLDSFVK 2446
Cdd:TIGR04523  573 LKQTQKslKKKQEEKQELIDQKEKEKKDLIKEIEEKEKKISSL----EKELEKAKKENEKLSSIIKNIKSKKNKLKQEVK 648


                   ..
gi 1720386946 2447 SM 2448
Cdd:TIGR04523  649 QI 650
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
725-990 1.10e-06

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 54.64  E-value: 1.10e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  725 ESAEEARSTLAAVTEE--RDQLLYQVKELD-VLAELRARVQELESSLAEAEKQrgldYESQRAQHNLLteqihSLSIEAK 801
Cdd:COG3206    145 PDPELAAAVANALAEAylEQNLELRREEARkALEFLEEQLPELRKELEEAEAA----LEEFRQKNGLV-----DLSEEAK 215

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  802 SKDVKIEALQRELDGVQLQFCEQGTQMKTLQSQLEAKEREVREGTErlrdiSQEMEGLSQALSQKELEIAKMDQLLLEKQ 881
Cdd:COG3206    216 LLLQQLSELESQLAEARAELAEAEARLAALRAQLGSGPDALPELLQ-----SPVIQQLRAQLAELEAELAELSARYTPNH 290

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  882 KDVETLQQTIQEKDQQVTElsfsmtekmvQLNEEKFSLGVEIKTLKEQLNLLSRTEEATKEQVEESGAgsslklghDESG 961
Cdd:COG3206    291 PDVIALRAQIAALRAQLQQ----------EAQRILASLEAELEALQAREASLQAQLAQLEARLAELPE--------LEAE 352

                          250       260
                   ....*....|....*....|....*....
gi 1720386946  962 QEGLQQELELLRKESEQRKRKLQAALINR 990
Cdd:COG3206    353 LRRLEREVEVARELYESLLQRLEEARLAE 381
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 788-1009 1.30e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 53.61  E-value: 1.30e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  788 LLTEQIHSLSIEAKSKDVKIEALQRELDGVQLQFCEQGTQMKTLQSQLEAKEREVREGTERLRDISQEMEGLSQALSQKE 867
Cdd:COG4942     10 LLALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELE 89

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  868 LEIAKMDQLLLEKQKDVETLQQTIQEKDQQVTEL----------SFSMTEKMVQLNEEKFSLGVEIKTLKEQLNLLSRTE 937
Cdd:COG4942     90 KEIAELRAELEAQKEELAELLRALYRLGRQPPLAlllspedfldAVRRLQYLKYLAPARREQAEELRADLAELAALRAEL 169

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1720386946  938 EATKEQVEESGAGSSLKLGHDESGQEGLQQELELLRKESEQRKRKLQAALINRKELLQKVSQLEEELAKVRE 1009
Cdd:COG4942    170 EAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAE 241
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1325-1767 1.40e-06

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 54.35  E-value: 1.40e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1325 LQDQINEQGLEIQNL----KAASVEAQAHTEllkQELESSQLKVAGLEHLKTLQPELDALHKHMGQKEEEVNYLYGQLSE 1400
Cdd:pfam15921  417 LRRELDDRNMEVQRLeallKAMKSECQGQME---RQMAAIQGKNESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLES 493

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1401 KEQTLTTVQTEMVEQERLIKALHTQLEMQAKEHEERLKQAQveicelkkkptELEEETNAKQQLQRKLQAALISRKEALK 1480
Cdd:pfam15921  494 SERTVSDLTASLQEKERAIEATNAEITKLRSRVDLKLQELQ-----------HLKNEGDHLRNVQTECEALKLQMAEKDK 562

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1481 ENKSLQEQLSSARDAV---ERLTKSLADVESQVSVQNQEKDAVLGKLTILQEERDKLIAEmdrflLENQSLSGSCESLKL 1557
Cdd:pfam15921  563 VIEILRQQIENMTQLVgqhGRTAGAMQVEKAQLEKEINDRRLELQEFKILKDKKDAKIRE-----LEARVSDLELEKVKL 637

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1558 ALGGltEDKEKLMEELESVRSSKMAESTEWQEKHKELQKEYEVLLQSYENVSNEAERIQHvvesvrqekqELYAKLRSTE 1637
Cdd:pfam15921  638 VNAG--SERLRAVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMETTTN----------KLKMQLKSAQ 705

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1638 SDKREREKQLQDAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEAQPVGGTGESMEALLSSNSSLKEELEKITLEH 1717
Cdd:pfam15921  706 SELEQTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATEK 785

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1718 KTLSKEFEALMAEKDALSEETRNLKLQVEAQVLKQASLEATEKSDEPKDV 1767
Cdd:pfam15921  786 NKMAGELEVLRSQERRLKEKVANMEVALDKASLQFAECQDIIQRQEQESV 835
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 2184-3030 1.67e-06

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 54.35  E-value: 1.67e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2184 DRVIDE----AKKWERRFGDAIQTKEEEVRLKEENCIALKDQLRQMAIHMEELKITVSRLEHDKEIWESKAQTELQHHQK 2259
Cdd:pfam15921   77 ERVLEEyshqVKDLQRRLNESNELHEKQKFYLRQSVIDLQTKLQEMQMERDAMADIRRRESQSQEDLRNQLQNTVHELEA 156

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2260 AYDKLQEENKELTSQLEDARQLYHDSKNELTKLESELKSLKDQttdlnnSLEKCKEHENNLEGIIKQQEADIQNCkfsCE 2339
Cdd:pfam15921  157 AKCLKEDMLEDSNTQIEQLRKMMLSHEGVLQEIRSILVDFEEA------SGKKIYEHDSMSTMHFRSLGSAISKI---LR 227

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2340 QLETDLaasreltSRLHDEINAKEQKIISLLSGKEEAIQLaveeLHQQHSKEIkelENLLSQEEEENVALEEENKRALEK 2419
Cdd:pfam15921  228 ELDTEI-------SYLKGRIFPVEDQLEALKSESQNKIEL----LLQQHQDRI---EQLISEHEVEITGLTEKASSARSQ 293

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2420 TNQLTEALEAIKKESFEQKAQldsFVKSMSSLQDDRDRIVSDYRQLEERHLSAIlekDQLIQDAAAENNKLKEEmrglRS 2499
Cdd:pfam15921  294 ANSIQSQLEIIQEQARNQNSM---YMRQLSDLESTVSQLRSELREAKRMYEDKI---EELEKQLVLANSELTEA----RT 363

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2500 HMDDLNSENAKLDAELVQYRRDLNeviaikdsQQKQLLDAQLQQNKELRNECTkleerlkgleaekqSLQMSSDALQKEK 2579
Cdd:pfam15921  364 ERDQFSQESGNLDDQLQKLLADLH--------KREKELSLEKEQNKRLWDRDT--------------GNSITIDHLRREL 421

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2580 QGLSKEIKNLQTQLTALQEEgtlgvYHAQLKAKEEELQRLNMALSSSQKRTADLEEelvcvQKEATRKVSEIEDQLKKEL 2659
Cdd:pfam15921  422 DDRNMEVQRLEALLKAMKSE-----CQGQMERQMAAIQGKNESLEKVSSLTAQLES-----TKEMLRKVVEELTAKKMTL 491

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2660 khlhhdagimrnetETAEERVAELARDLVEMEQKLltvtkenkdlmaqiqafgrsmsslqdsrDHATEELGDLKKKYDAS 2739
Cdd:pfam15921  492 --------------ESSERTVSDLTASLQEKERAI----------------------------EATNAEITKLRSRVDLK 529

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2740 LKELAQLKEwqdssrEGDVLsqaafplstsENVLSRLEKLNQQLTSKDEQLLHLSSELESSHNQVQSISKAMTSLQNERD 2819
Cdd:pfam15921  530 LQELQHLKN------EGDHL----------RNVQTECEALKLQMAEKDKVIEILRQQIENMTQLVGQHGRTAGAMQVEKA 593

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2820 RLWSE-------LEKFRKSEEGKQ-RAAAPSAASSPAEVQSLK---------KAMSSLQNDRDRLLKELKNLQQQYLQMS 2882
Cdd:pfam15921  594 QLEKEindrrleLQEFKILKDKKDaKIRELEARVSDLELEKVKlvnagserlRAVKDIKQERDQLLNEVKTSRNELNSLS 673

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2883 QEMTELRplkaqlQESQDQTKALQVMEEELRQENLSWQHELRQLRMEKNSWE---LHERRMKEQFLMAISDKDQQLGHLQ 2959
Cdd:pfam15921  674 EDYEVLK------RNFRNKSEEMETTTNKLKMQLKSAQSELEQTRNTLKSMEgsdGHAMKVAMGMQKQITAKRGQIDALQ 747

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1720386946 2960 S----LLRELRSSSQAQILSTQYQRQASPETSASLDGSQKLVYETELLRTQLNDSLKEIHQKELRIQQLNSKFSQ 3030
Cdd:pfam15921  748 SkiqfLEEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANMEVALDKASLQFAE 822
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
2084-2659 1.96e-06

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 53.91  E-value: 1.96e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2084 KKELQSNKESIKSQIKQKDEDLLRRLEQAEEKhRKEKKNMQEKLDALHREKAHVEET---LAEIQVSLTRKDQEMKELQG 2160
Cdd:PRK03918   181 LEKFIKRTENIEELIKEKEKELEEVLREINEI-SSELPELREELEKLEKEVKELEELkeeIEELEKELESLEGSKRKLEE 259

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2161 SLDSTLAQLAAFTKSMSSLQDDRDRVID---EAKKWERRFGDAIQTKEEEVRLKEENCIaLKDQLRQMAIHMEELKITVS 2237
Cdd:PRK03918   260 KIRELEERIEELKKEIEELEEKVKELKElkeKAEEYIKLSEFYEEYLDELREIEKRLSR-LEEEINGIEERIKELEEKEE 338

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2238 RLEhdkeiWESKAQTELQHHQKAYDKLQEENKELTSQLEDARQLYHDSKN-ELTKLESELKSLKDQTTDLNNSLEKCKEH 2316
Cdd:PRK03918   339 RLE-----ELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGlTPEKLEKELEELEKAKEEIEEEISKITAR 413

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2317 ENNLEGIIKQQEADIQNCKFS------CEQLETDlAASRELTSRLHDEINAKEQKIISLLSGKEEAIQLAVE-------- 2382
Cdd:PRK03918   414 IGELKKEIKELKKAIEELKKAkgkcpvCGRELTE-EHRKELLEEYTAELKRIEKELKEIEEKERKLRKELRElekvlkke 492

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2383 -ELHQQHS--KEIKELENLLSQEEEENVALEEENKRAL-EKTNQLTEALEAIKKESFEQKAQLDSFVKSMSSLQDDRDRI 2458
Cdd:PRK03918   493 sELIKLKElaEQLKELEEKLKKYNLEELEKKAEEYEKLkEKLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEEL 572

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2459 VSDYRQLEERHLSAILEKDQLIQDAAAENNKLKEeMRGLRSHMDDLNSENAKLDAELVQYRRDLNEVIAIKDSQQKQLLD 2538
Cdd:PRK03918   573 AELLKELEELGFESVEELEERLKELEPFYNEYLE-LKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEE 651

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2539 AQLQQNKE----LRNECTKLEERLKGLEAEKQSlqmssdaLQKEKQGLSKEIKNLQTQLTALQEegtlgvyhaqlkaKEE 2614
Cdd:PRK03918   652 LEKKYSEEeyeeLREEYLELSRELAGLRAELEE-------LEKRREEIKKTLEKLKEELEEREK-------------AKK 711

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*
gi 1720386946 2615 ELQRLNMALSSSQKRTADLEEELVCVQKEATRKVSEIEDQLKKEL 2659
Cdd:PRK03918   712 ELEKLEKALERVEELREKVKKYKALLKERALSKVGEIASEIFEEL 756
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 680-1103 2.18e-06

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 53.97  E-value: 2.18e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  680 ELERLKTQVLELETSLHTAEETYKRNLsekvkeissltqlsEEVKESAEEARSTLAAVTEERDQLLYQVKELD-----VL 754
Cdd:pfam15921  318 QLSDLESTVSQLRSELREAKRMYEDKI--------------EELEKQLVLANSELTEARTERDQFSQESGNLDdqlqkLL 383

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  755 AELRARVQELesSLAEAEKQRGLDYESQRA-QHNLLTEQIHSLSIEAKSKDVKIEALQRELDGvqlqfcEQGTQMKTLQS 833
Cdd:pfam15921  384 ADLHKREKEL--SLEKEQNKRLWDRDTGNSiTIDHLRRELDDRNMEVQRLEALLKAMKSECQG------QMERQMAAIQG 455

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  834 QLEAKER------EVREGTERLRDISQEMEGLSQALSQKELEIAKMDQLLLEKQKDVETLQQTIQEKDQQVtELSFSMTE 907
Cdd:pfam15921  456 KNESLEKvssltaQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEATNAEITKLRSRV-DLKLQELQ 534

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  908 KMVQLNEEKFSLGVEIKTLKEQLNLLSRTEEATKEQVEESgagsSLKLGHDESGQEGLQQELELLRKESEQRKRKLQAAL 987
Cdd:pfam15921  535 HLKNEGDHLRNVQTECEALKLQMAEKDKVIEILRQQIENM----TQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQEFK 610

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  988 INR-------KELLQKVSQLEEELAKV-----------------REDSRKEIPFGENERRKLEED-----RENRDDPEEW 1038
Cdd:pfam15921  611 ILKdkkdakiRELEARVSDLELEKVKLvnagserlravkdikqeRDQLLNEVKTSRNELNSLSEDyevlkRNFRNKSEEM 690

                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1720386946 1039 GTSKWReveasLKQTISEKEVELEGIRRDLKEKTAAEEELQAVVQRMTRDLQSKTKQIDLLQEEV 1103
Cdd:pfam15921  691 ETTTNK-----LKMQLKSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKI 750
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
2106-2704 2.26e-06

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 53.53  E-value: 2.26e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2106 LRRLEQAEEKHRKEKKNMQEKLDALHRE---KAHVEETLAEIQVSLTRKDQEMKELQGSLDSTLAQLAAFTKSMSSLQDD 2182
Cdd:PRK03918   157 LDDYENAYKNLGEVIKEIKRRIERLEKFikrTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEEL 236

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2183 RDRVIDEAKKWERRFGDAiqtKEEEVRLKEenciaLKDQLRQMAIHMEELKITVSRLEhdkeiweskaqtELQHHQKAYD 2262
Cdd:PRK03918   237 KEEIEELEKELESLEGSK---RKLEEKIRE-----LEERIEELKKEIEELEEKVKELK------------ELKEKAEEYI 296

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2263 KLQEENKELTSQLEDArqlyhdsKNELTKLESELKSLKDQTTDLNNSLEKCKEHENNLEGIIKQQEAdIQNCKFSCEQLE 2342
Cdd:PRK03918   297 KLSEFYEEYLDELREI-------EKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEE-LEERHELYEEAK 368

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2343 TDLAASRELTSRLHDEINAKEQKIISLLSGKEEAIQLAVEELHQqhskEIKELENLLSQEEEENVALEEENKRALEKTNQ 2422
Cdd:PRK03918   369 AKKEELERLKKRLTGLTPEKLEKELEELEKAKEEIEEEISKITA----RIGELKKEIKELKKAIEELKKAKGKCPVCGRE 444

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2423 LTEAleaikkesfEQKAQLDSFVKSMSSLQDDRDRIVSDYRQLEERHLSaiLEKDQLIQDAAAENNKLKEEMRGLRSHMD 2502
Cdd:PRK03918   445 LTEE---------HRKELLEEYTAELKRIEKELKEIEEKERKLRKELRE--LEKVLKKESELIKLKELAEQLKELEEKLK 513

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2503 DLNSENAKLDAElvQYRRDLNEVIAIKdSQQKQLLDaQLQQNKELRNECTKLEERLKGLEAEKQSLQ--------MSSDA 2574
Cdd:PRK03918   514 KYNLEELEKKAE--EYEKLKEKLIKLK-GEIKSLKK-ELEKLEELKKKLAELEKKLDELEEELAELLkeleelgfESVEE 589

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2575 LQKEKQGLSK------EIKNLQTQLTALQEEgtLGVYHAQLKAKEEELQRLNMALSSSQKRtadLEEELVCVQKEATRKV 2648
Cdd:PRK03918   590 LEERLKELEPfyneylELKDAEKELEREEKE--LKKLEEELDKAFEELAETEKRLEELRKE---LEELEKKYSEEEYEEL 664

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1720386946 2649 SEIEDQLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLTVTKENKDL 2704
Cdd:PRK03918   665 REEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKAKKELEKLEKAL 720
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 1400-2204 2.91e-06

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 53.30  E-value: 2.91e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1400 EKEQTLTTVQTEMVE--QERLIKALHTQLEMQAKEHEERLKQAQVEICELKKKPTELEEETNAKQQLQRKLQAALISRKE 1477
Cdd:pfam12128  190 SKEGKFRDVKSMIVAilEDDGVVPPKSRLNRQQVEHWIRDIQAIAGIMKIRPEFTKLQQEFNTLESAELRLSHLHFGYKS 269

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1478 ALKENKSLQEQLSSARDAVERLTKSL-ADVESQVSVQNQEKDAVLGKLTILQEERDKLIAEMDRFLLENqslsgsCESLK 1556
Cdd:pfam12128  270 DETLIASRQEERQETSAELNQLLRTLdDQWKEKRDELNGELSAADAAVAKDRSELEALEDQHGAFLDAD------IETAA 343

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1557 LALggltedkeklmEELESVRS--SKMAESTEWQE-KHKELQKEYEVLLQsyeNVSNEAERIQHVVESVRQEKQELYAKL 1633
Cdd:pfam12128  344 ADQ-----------EQLPSWQSelENLEERLKALTgKHQDVTAKYNRRRS---KIKEQNNRDIAGIKDKLAKIREARDRQ 409

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1634 RSTESDKRER-EKQLQDaeqemeEMKEKMRKFAKSKQQKILELEEENDRLrAEAQPVGGTGESMEALLSSNSSLKEELEK 1712
Cdd:pfam12128  410 LAVAEDDLQAlESELRE------QLEAGKLEFNEEEYRLKSRLGELKLRL-NQATATPELLLQLENFDERIERAREEQEA 482

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1713 ITLEHKTLSKEFEALMAEKDALSEETRNLKLQVEAQVLKQASLEaTEKSDEPKDVIEEVTQAVVGKSQERDALSDSAKLE 1792
Cdd:pfam12128  483 ANAEVERLQSELRQARKRRDQASEALRQASRRLEERQSALDELE-LQLFPQAGTLLHFLRKEAPDWEQSIGKVISPELLH 561

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1793 DSEAILMGDGAKPGVSETFSS------HDDIKNYLQQLDQLKGRIAELEMEKQKDRELSQALENEknalLTQISAKDSEL 1866
Cdd:pfam12128  562 RTDLDPEVWDGSVGGELNLYGvkldlkRIDVPEWAASEEELRERLDKAEEALQSAREKQAAAEEQ----LVQANGELEKA 637

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1867 KLleEEVTKRTTLnQQIQEELCRVT--------KLKETAEEEKDDLEERLMNQLAELNgSIGNYYQDVTdAQIKNEQLES 1938
Cdd:pfam12128  638 SR--EETFARTAL-KNARLDLRRLFdekqsekdKKNKALAERKDSANERLNSLEAQLK-QLDKKHQAWL-EEQKEQKREA 712

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1939 EMRNLQRCVSELEEEKQQLVKEKTKVESEirkeymekiqgaqkgpaNKSHAKELQELLREKQQEVKQLQKDCirylERIS 2018
Cdd:pfam12128  713 RTEKQAYWQVVEGALDAQLALLKAAIAAR-----------------RSGAKAELKALETWYKRDLASLGVDP----DVIA 771

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2019 ALEKTVKalefvhtesqkdldvtkgNLAQAVEHRKKAQAELSSFKILLDDTQSEAARVLADNLklkKELQSNKESIKSQI 2098
Cdd:pfam12128  772 KLKREIR------------------TLERKIERIAVRRQEVLRYFDWYQETWLQRRPRLATQL---SNIERAISELQQQL 830

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2099 KQKDEDLLRRLeQAEEKHRKEKKNMQEKLDALHREKAHVEETLAEIQVsltrkDQEMKELQGSLDSTLAQLaaftksmSS 2178
Cdd:pfam12128  831 ARLIADTKLRR-AKLEMERKASEKQQVRLSENLRGLRCEMSKLATLKE-----DANSEQAQGSIGERLAQL-------ED 897

                          810       820
                   ....*....|....*....|....*.
gi 1720386946 2179 LQDDRDRVIDEAKKWERRFGDAIQTK 2204
Cdd:pfam12128  898 LKLKRDYLSESVKKYVEHFKNVIADH 923
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 1830-2592 3.19e-06

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 53.13  E-value: 3.19e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1830 RIAELEMEKQKDRELSQALENEKNALLTQISAKDSELKLLEEEVTKRTTLNQQIQEELcrvtklkETAEEEKDDLEERLM 1909
Cdd:TIGR00606  320 ELVDCQRELEKLNKERRLLNQEKTELLVEQGRLQLQADRHQEHIRARDSLIQSLATRL-------ELDGFERGPFSERQI 392

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1910 NQLAELNGSiGNYYQDVTDAQIKNEqLESEMRNLQRCVSELEEEKQQL---VKEKTKVESEIRKEYMEKIQGAQKGPANK 1986
Cdd:TIGR00606  393 KNFHTLVIE-RQEDEAKTAAQLCAD-LQSKERLKQEQADEIRDEKKGLgrtIELKKEILEKKQEELKFVIKELQQLEGSS 470

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1987 SHAKELQELLREKQQEVKQLQKDcirylerisALEKTVKALEFVHTESQKDLDVTKGNLAQAVEHRKKAQAELSSFKILL 2066
Cdd:TIGR00606  471 DRILELDQELRKAERELSKAEKN---------SLTETLKKEVKSLQNEKADLDRKLRKLDQEMEQLNHHTTTRTQMEMLT 541

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2067 DDTQSEAARV-------------LADNLKLKKELQSNKESIKSQIKQKDEDL------LRRLEQAEEKHRKEKKNMQEKL 2127
Cdd:TIGR00606  542 KDKMDKDEQIrkiksrhsdeltsLLGYFPNKKQLEDWLHSKSKEINQTRDRLaklnkeLASLEQNKNHINNELESKEEQL 621

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2128 DALHREKAHVEETLAEiQVSLTRKDQEMKELQGSLDSTLAQLAAFTKSMSSLQDDRDRVIDEAKKwerrfgdAIQTKEEe 2207
Cdd:TIGR00606  622 SSYEDKLFDVCGSQDE-ESDLERLKEEIEKSSKQRAMLAGATAVYSQFITQLTDENQSCCPVCQR-------VFQTEAE- 692

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2208 vrlKEENCIALKDQLRQMAIHMEELKITVSRLEHDKEIWESKA---QTELQHHQKAYDKLQEENKELTSQLEDARQLYHD 2284
Cdd:TIGR00606  693 ---LQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLApgrQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEE 769

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2285 SKNELTKLESELKSLKDQTTDLNnSLEKCKEHENNLEGIIKQQEADIQ-----------NCKFSCEQLETDLAASR-ELT 2352
Cdd:TIGR00606  770 QETLLGTIMPEEESAKVCLTDVT-IMERFQMELKDVERKIAQQAAKLQgsdldrtvqqvNQEKQEKQHELDTVVSKiELN 848

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2353 SRLHDEINAKEQKIISLLSG-KEEAIQL--------AVEELHQQHSKEIKELENLLSQEEEENVALEEENKRALEKTNQL 2423
Cdd:TIGR00606  849 RKLIQDQQEQIQHLKSKTNElKSEKLQIgtnlqrrqQFEEQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEEL 928

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2424 TEALEAIKKESFEQ----KAQLDSFVKSMSSLQDDRDRIVSDYRQLEERHLSAILEKdqlIQDAAAENNKLKEEMRGLRS 2499
Cdd:TIGR00606  929 ISSKETSNKKAQDKvndiKEKVKNIHGYMKDIENKIQDGKDDYLKQKETELNTVNAQ---LEECEKHQEKINEDMRLMRQ 1005

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2500 HMDDLNSENAKLDAELVQYRRDlNEVIAIKDSQQKQLLDAQLQQNKELRNECTKLEERLKGLEAEKQSLQMSSDALQKEK 2579
Cdd:TIGR00606 1006 DIDTQKIQERWLQDNLTLRKRE-NELKEVEEELKQHLKEMGQMQVLQMKQEHQKLEENIDLIKRNHVLALGRQKGYEKEI 1084

                          810
                   ....*....|...
gi 1720386946 2580 QGLSKEIKNLQTQ 2592
Cdd:TIGR00606 1085 KHFKKELREPQFR 1097
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1446-1650 3.27e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 52.46  E-value: 3.27e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1446 ELKKKPTELEEETNAKQQLQRKLQAALISRKEALKENKSLQEQLSSARDAVERLTKSLADVESQVSVQNQEKDAVLGKLT 1525
Cdd:COG4942     21 AAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELE 100

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1526 ILQEERDKLIAEMDR--------FLLENQSLSGSCESLKLaLGGLTEDKEKLMEELEsvrsskmAESTEWQEKHKELQKE 1597
Cdd:COG4942    101 AQKEELAELLRALYRlgrqpplaLLLSPEDFLDAVRRLQY-LKYLAPARREQAEELR-------ADLAELAALRAELEAE 172

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1720386946 1598 YEVLLQSYENVSNEAERIqhvvESVRQEKQELYAKLRSTESDKREREKQLQDA 1650
Cdd:COG4942    173 RAELEALLAELEEERAAL----EALKAERQKLLARLEKELAELAAELAELQQE 221
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1310-1960 3.41e-06

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 53.10  E-value: 3.41e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1310 SIASELAKKSEEVLLLQDQINEQGLEIQNLKAASVEAQAHTELLKQELESSQLKVAGL-EHLKTLQPELDALHKHMGQKE 1388
Cdd:TIGR04523   44 TIKNELKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLnSDLSKINSEIKNDKEQKNKLE 123

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1389 EEVNYLYGQLSEKEQTLTTVQTEMVEQERLIKALHTQLEMQAKEHEERLKQAQVEICELKKKPTELeeeTNAKQQLqRKL 1468
Cdd:TIGR04523  124 VELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNI---DKIKNKL-LKL 199

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1469 QAALISRKEALKENKSLQEQLSSARDAVERLTKSLADVESQVSVQNQEKDAVLGKLTILQEERDKLIAEMDRFLLEnqsl 1548
Cdd:TIGR04523  200 ELLLSNLKKKIQKNKSLESQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKE---- 275

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1549 sgsCESLKLALGGLTEDKEKLMEELESVRSSKMaestewQEKHKELQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQE 1628
Cdd:TIGR04523  276 ---LEQNNKKIKELEKQLNQLKSEISDLNNQKE------QDWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQ 346

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1629 LYAKLRSTESDKREREKQLqdaeqemeemkekmrkfaKSKQQKILELEEENDRLRaeaqpvggtgESMEALLSSNSSLKE 1708
Cdd:TIGR04523  347 LKKELTNSESENSEKQREL------------------EEKQNEIEKLKKENQSYK----------QEIKNLESQINDLES 398

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1709 ELEKITLEHKTLSKEFEALMAEKDALSEETRNLKLQVEAQvlKQASLEATEKSDEPKDVIEEVTQAVVGKSQERDALSDS 1788
Cdd:TIGR04523  399 KIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKN--NSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRS 476

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1789 AKLEDSEailmgdgAKPGVSETFSSHDDIKNYLQQLDQLKGRIAELEMEKQKDRELSQALENEKNALLTQISAKDSELKL 1868
Cdd:TIGR04523  477 INKIKQN-------LEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNK 549

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1869 LEEEVTKrTTLNQQIQEELCRVTKLKETAEEEKDDLEER-------------LMNQLAELNGSIGNYYQDVTDAQIKNEQ 1935
Cdd:TIGR04523  550 DDFELKK-ENLEKEIDEKNKEIEELKQTQKSLKKKQEEKqelidqkekekkdLIKEIEEKEKKISSLEKELEKAKKENEK 628

                          650       660
                   ....*....|....*....|....*
gi 1720386946 1936 LESEMRNLQRCVSELEEEKQQLVKE 1960
Cdd:TIGR04523  629 LSSIIKNIKSKKNKLKQEVKQIKET 653
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
711-946 3.58e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 53.00  E-value: 3.58e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  711 KEISSLTQL-------SEEVKESAEEARSTLAAVTEERDQLLYQVKELDVLAELRARVQELESSLAEAEKQRGLD----- 778
Cdd:COG4913    204 KPIGDLDDFvreymleEPDTFEAADALVEHFDDLERAHEALEDAREQIELLEPIRELAERYAAARERLAELEYLRaalrl 283

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  779 YESQRAQHNL------LTEQIHSLSIEAKSKDVKIEALQRELDGVQLQFCEQGTQmktlqsQLEAKEREVREGTERLRDI 852
Cdd:COG4913    284 WFAQRRLELLeaeleeLRAELARLEAELERLEARLDALREELDELEAQIRGNGGD------RLEQLEREIERLERELEER 357

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  853 SQEMEGLSQALSQKELEIAKMDQLLLEKQKDVETLQQTIQEKDQQVTELSFSMTEKMVQLNEEKFSLGVEIKTLKEQLNL 932
Cdd:COG4913    358 ERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSN 437

                          250
                   ....*....|....
gi 1720386946  933 LSRTEEATKEQVEE 946
Cdd:COG4913    438 IPARLLALRDALAE 451
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
2092-2563 4.05e-06

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 52.73  E-value: 4.05e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2092 ESIKSQIKQKDE-DLLRRLEQaeekHRKEKKNMQEKLDALHREKAHVEETLAEIQVSLTRKDQEMKELQgSLDSTLAQLA 2170
Cdd:PRK02224   190 DQLKAQIEEKEEkDLHERLNG----LESELAELDEEIERYEEQREQARETRDEADEVLEEHEERREELE-TLEAEIEDLR 264

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2171 AFTKSMSSLQDDRDRVIDEAKKWERRFGDAIQTKEEEVRLKEENCIALKDQLRQMAIHMEELKIT-----VSRLEHDKEI 2245
Cdd:PRK02224   265 ETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRleecrVAAQAHNEEA 344

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2246 wESKAQTELQHHQKAyDKLQEENKELTSQLEDARQLYHDSKNELTKLESELKSLK----DQTTDLNNS---LEKCKEHEN 2318
Cdd:PRK02224   345 -ESLREDADDLEERA-EELREEAAELESELEEAREAVEDRREEIEELEEEIEELRerfgDAPVDLGNAedfLEELREERD 422

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2319 NLEGIIKQQEADIQNCKFSCEQLETDLAASR-------------------------ELTSRLHD---EINAKEQKIISLL 2370
Cdd:PRK02224   423 ELREREAELEATLRTARERVEEAEALLEAGKcpecgqpvegsphvetieedrerveELEAELEDleeEVEEVEERLERAE 502

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2371 SGKEEAIQL--------AVEELHQQHSKEIKE----LENLLSQEEEENVALEEENKRALEKTNQLTEALEAIkKESFEQK 2438
Cdd:PRK02224   503 DLVEAEDRIerleerreDLEELIAERRETIEEkrerAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEV-AELNSKL 581

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2439 AQLDSFVKSMSSLQDDRDRIVSDYRQLEERH--LSAILEKDQLIQDAAAEnnkLKEEMRGLRSHMDDLNSENAKLD-AEL 2515
Cdd:PRK02224   582 AELKERIESLERIRTLLAAIADAEDEIERLRekREALAELNDERRERLAE---KRERKRELEAEFDEARIEEAREDkERA 658

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1720386946 2516 VQYRRDLNEVIAIKDSQQKQLLDA------QLQQNKELRNECTKLEERLKGLEA 2563
Cdd:PRK02224   659 EEYLEQVEEKLDELREERDDLQAEigavenELEELEELRERREALENRVEALEA 712
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1810-2026 4.11e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 52.07  E-value: 4.11e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1810 TFSSHDDIKNYLQQLDQLKGRIAELEMEKQKDRELSQALENEKNALLTQISAKDSELKLLEEEVtkrttlnQQIQEELCR 1889
Cdd:COG4942     15 AAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQEL-------AALEAELAE 87

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1890 VTKLKETAEEEKDDLEERLMNQLAELNGSIGNYY-------QDVTDAQIK-------NEQLESEMRNLQRCVSELEEEKQ 1955
Cdd:COG4942     88 LEKEIAELRAELEAQKEELAELLRALYRLGRQPPlalllspEDFLDAVRRlqylkylAPARREQAEELRADLAELAALRA 167

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1720386946 1956 QLVKEKTKVESEIRKEYMEKIQGAQKGPANKSHAKELQELLREKQQEVKQLQKDCIRYLERISALEKTVKA 2026
Cdd:COG4942    168 ELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAA 238
PTZ00121 PTZ00121
MAEBL; Provisional
 708-1223 6.66e-06

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 52.45  E-value: 6.66e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  708 EKVKEISSLTQLSEEVKESAEEARSTLAAVTEERDQLLYQVKELDVLAELRARVQELEsslaEAEKQRGLDyESQRAQHN 787
Cdd:PTZ00121  1227 EAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELK----KAEEKKKAD-EAKKAEEK 1301

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  788 LLTEQIHSLSIEAKSKD---VKIEALQRELDGVQLQFCEQGTQMKTLQSQLEAKEREVREGTERlrdisQEMEGLSQALS 864
Cdd:PTZ00121  1302 KKADEAKKKAEEAKKADeakKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEK-----AEAAEKKKEEA 1376

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  865 QKELEIAKMDQlllEKQKDVETLQQTIQEKDQQVTELSFSMTEKmvQLNEEKFSLGVEIKT---LKEQLNLLSRTEEATK 941
Cdd:PTZ00121  1377 KKKADAAKKKA---EEKKKADEAKKKAEEDKKKADELKKAAAAK--KKADEAKKKAEEKKKadeAKKKAEEAKKADEAKK 1451

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  942 EQVEESGAGSSLKLGHDESGQEGLQQELELLRKESEQRKRKLQAalinrKELLQKVSQLEEELAKVREDSRKEIPFGENE 1021
Cdd:PTZ00121  1452 KAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEA-----KKKADEAKKAAEAKKKADEAKKAEEAKKADE 1526

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1022 RRKLEEDRENRDDPEEWGTSKWREVEASlkqtiseKEVELEGIRRDLKEKTAAEEELQAVVQRMTRDLQSKTKQIDLLQE 1101
Cdd:PTZ00121  1527 AKKAEEAKKADEAKKAEEKKKADELKKA-------EELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMK 1599

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1102 EVTENQatiqklvtgTMDAGNGGSAAPVKETAASSPPGAggEEHWKPELEGRILDLEKDKTQLQKKLQEALIARKAILKK 1181
Cdd:PTZ00121  1600 LYEEEK---------KMKAEEAKKAEEAKIKAEELKKAE--EEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAK 1668

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|..
gi 1720386946 1182 AQEKEKQLKEELREQKDAYHHLQGQFHEQNKEKENiADQLRQ 1223
Cdd:PTZ00121  1669 KAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKK-AEELKK 1709
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2104-2312 7.36e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 51.30  E-value: 7.36e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2104 DLLRRLEQAEEKHRKEKKNMQEKLDALHREKAHVEETLAEIQVSLTRKDQEMKELQGSLDSTLAQLAAFTKSMSSLQDDR 2183
Cdd:COG4942     20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAEL 99

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2184 D-------RVIDEAKKWERRFGDAIQTKEEEVRLKEENCIALKDQLRQMAIHMEELKITVSRLEHDKEiwesKAQTELQH 2256
Cdd:COG4942    100 EaqkeelaELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRA----ELEAERAE 175

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1720386946 2257 HQKAYDKLQEENKELTSQLEDARQLYHDSKNELTKLESELKSLKDQTTDLNNSLEK 2312
Cdd:COG4942    176 LEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIAR 231
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
677-1113 1.01e-05

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 51.60  E-value: 1.01e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  677 HQGELERLKTQVLELETSLHTAEETYK---RNLSEKVKEISSLTQLSEEVKESAEEAR--STLAAVTEERDQLLYQVKEL 751
Cdd:PRK03918   236 LKEEIEELEKELESLEGSKRKLEEKIReleERIEELKKEIEELEEKVKELKELKEKAEeyIKLSEFYEEYLDELREIEKR 315

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  752 -----DVLAELRARVQELESSLAEAEKQRGLDYESQRAQHNLltEQIHSLSIEAKSKDVKIEALQRELDGVQLQFCEQgt 826
Cdd:PRK03918   316 lsrleEEINGIEERIKELEEKEERLEELKKKLKELEKRLEEL--EERHELYEEAKAKKEELERLKKRLTGLTPEKLEK-- 391

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  827 QMKTLQSQLEAKEREVREGTERLRDISQEMEGLSQALSQ------------KELEIAKMDQLLLEKQKDVETLQQTIQEK 894
Cdd:PRK03918   392 ELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEElkkakgkcpvcgRELTEEHRKELLEEYTAELKRIEKELKEI 471

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  895 DQQVTELSFSMTEKMVQLNEEK-----FSLGVEIKTLKEQLNLLSRTEEATKEQVEESGAGSSLKLGHDESGQEGLQQEL 969
Cdd:PRK03918   472 EEKERKLRKELRELEKVLKKESeliklKELAEQLKELEEKLKKYNLEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKL 551

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  970 ELLRKESEQRKRKLQAALINRKELLQK--------VSQLEEELAKVREDSRKEIPFGENERRKleEDRENRDDPEEWGTS 1041
Cdd:PRK03918   552 EELKKKLAELEKKLDELEEELAELLKEleelgfesVEELEERLKELEPFYNEYLELKDAEKEL--EREEKELKKLEEELD 629

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1720386946 1042 KWREVEASLKQTISEKEVELEGIRRDLKEKTaaEEELQAVVQRMTRDLQSKTKQIDLLQEEVTENQATIQKL 1113
Cdd:PRK03918   630 KAFEELAETEKRLEELRKELEELEKKYSEEE--YEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKL 699
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1487-2033 1.11e-05

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 51.58  E-value: 1.11e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1487 EQLSSARDAVERLTK----SLADVESQVSvQNQEKDAVlGKLTILQEERDKLIAEMDRFLLENQSLSGSCESLKLALGGL 1562
Cdd:PRK02224   169 ERASDARLGVERVLSdqrgSLDQLKAQIE-EKEEKDLH-ERLNGLESELAELDEEIERYEEQREQARETRDEADEVLEEH 246

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1563 TEDKEKL------MEELESVRSSKMAESTEWQEKHKELQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQELYAKLRST 1636
Cdd:PRK02224   247 EERREELetleaeIEDLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEEL 326

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1637 ESDKREREKQLQDAEQEmeemkekmrkfAKSKQQKILELEEENDRLRAEAQPVGGTGESMEALLSSNSSLKEELEKitlE 1716
Cdd:PRK02224   327 RDRLEECRVAAQAHNEE-----------AESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEE---E 392

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1717 HKTLSKEFEALMAEKDALSEETRNLKLQVEAQVLKQASLEATEKSDEpkDVIEEVTQAV-----------VGKSQERDAL 1785
Cdd:PRK02224   393 IEELRERFGDAPVDLGNAEDFLEELREERDELREREAELEATLRTAR--ERVEEAEALLeagkcpecgqpVEGSPHVETI 470

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1786 SDS-AKLEDSEAILmgdgakpgvSETFSSHDDIKNYLQQLDQLKGRIAELEMEKQKdRELSQALENEKNALLTQISAKDS 1864
Cdd:PRK02224   471 EEDrERVEELEAEL---------EDLEEEVEEVEERLERAEDLVEAEDRIERLEER-REDLEELIAERRETIEEKRERAE 540

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1865 EL-----KLLEEEVTKR---TTLNQQIQEELCRVTKLKETAEEEKDDLEErlMNQLAELNGSIGNYYQDVTDAQIKNEQL 1936
Cdd:PRK02224   541 ELreraaELEAEAEEKReaaAEAEEEAEEAREEVAELNSKLAELKERIES--LERIRTLLAAIADAEDEIERLREKREAL 618

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1937 esemrnlqrcvSELEEEKQQLVKEKTKVESEIRKEYME-KIQGAQKGPAN-KSHAKELQELLREKQQEVKQLQKDC---- 2010
Cdd:PRK02224   619 -----------AELNDERRERLAEKRERKRELEAEFDEaRIEEAREDKERaEEYLEQVEEKLDELREERDDLQAEIgave 687

                          570       580
                   ....*....|....*....|....*....
gi 1720386946 2011 --IRYLE----RISALEKTVKALEFVHTE 2033
Cdd:PRK02224   688 neLEELEelreRREALENRVEALEALYDE 716
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
754-1026 1.25e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 51.45  E-value: 1.25e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  754 LAELRARVQELESSLAEAEKQRgldyESQRAQHNLLTEQIHSLS--IEAKSKDVKIEALQRELDGV--QLQFCEQG-TQM 828
Cdd:COG4913    612 LAALEAELAELEEELAEAEERL----EALEAELDALQERREALQrlAEYSWDEIDVASAEREIAELeaELERLDASsDDL 687

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  829 KTLQSQLEAKEREVREGTERLRDISQEMEGLSQALSQKELEIAKMDQLLLEKQKDVETLQQtiQEKDQQVTELSFSMTEK 908
Cdd:COG4913    688 AALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELR--ALLEERFAAALGDAVER 765

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  909 MVQLNeekfsLGVEIKTLKEQLNLLSRTEEATKEQVEESGAGSSLKLGHDESGQEGLQQELELLRKES----EQR-KRKL 983
Cdd:COG4913    766 ELREN-----LEERIDALRARLNRAEEELERAMRAFNREWPAETADLDADLESLPEYLALLDRLEEDGlpeyEERfKELL 840

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*....
gi 1720386946  984 QAALINRKELLQkvSQLEEELAKVRE------DSRKEIPFGENERRKLE 1026
Cdd:COG4913    841 NENSIEFVADLL--SKLRRAIREIKEridplnDSLKRIPFGPGRYLRLE 887
PTZ00121 PTZ00121
MAEBL; Provisional
 1722-2566 1.33e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 51.30  E-value: 1.33e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1722 KEFEALMAEKDALSEETRN-LKLQVEAQVLKQASLEATEKSDEPKDVIEEVTQAV-VGKSQERDALSDSAKLEDSEAILM 1799
Cdd:PTZ00121  1077 KDFDFDAKEDNRADEATEEaFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEeARKAEDARKAEEARKAEDAKRVEI 1156

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1800 GDGAKPGVSETFSSHDDiknylqqlDQLKGRIAELEMEKQKDRELSQALENEKnallTQISAKDSELKLLEEevtKRTTL 1879
Cdd:PTZ00121  1157 ARKAEDARKAEEARKAE--------DAKKAEAARKAEEVRKAEELRKAEDARK----AEAARKAEEERKAEE---ARKAE 1221

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1880 NQQIQEELCRVTKLKETAEEEKDDLEERLMNQLAELNGSIGNYYQDvTDAQIKNEQlesemrnlQRCVSELEEekqqlVK 1959
Cdd:PTZ00121  1222 DAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFAR-RQAAIKAEE--------ARKADELKK-----AE 1287

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1960 EKTKVESEIRKEYMEKIQGAQKGPANKSHAKELQELLREKQQEVKQLQKdciryleriSALEKTVKAlefvhtesqkdld 2039
Cdd:PTZ00121  1288 EKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKK---------KAEEAKKAA------------- 1345

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2040 vtkgNLAQAVEHRKKAQAELSSFKILLDDTQSEAARVLADNLKLKKELQSNKESIKSQIKQ--KDEDLLRRLEQAEEKHR 2117
Cdd:PTZ00121  1346 ----EAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEdkKKADELKKAAAAKKKAD 1421

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2118 KEKKNMQEKLDALHREKAHVEETLAEiqvSLTRKDQEMKELQGSLDSTlaqlaaftksmsslqdDRDRVIDEAKK--WER 2195
Cdd:PTZ00121  1422 EAKKKAEEKKKADEAKKKAEEAKKAD---EAKKKAEEAKKAEEAKKKA----------------EEAKKADEAKKkaEEA 1482

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2196 RFGDAIQTKEEEVRLKEENcialkdqlrqmAIHMEELKITVSRLEHDKEIWESKAQTELQHHQKAYDKLQEENKELTSQL 2275
Cdd:PTZ00121  1483 KKADEAKKKAEEAKKKADE-----------AKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADEL 1551

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2276 EDARQLyhDSKNELTKLESELKSLKDQTTDLNNSLEKCKEHENNLEGIIKQQEadiQNCKFSCEQLEtdlaasreltsrl 2355
Cdd:PTZ00121  1552 KKAEEL--KKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYE---EEKKMKAEEAK------------- 1613

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2356 hdeiNAKEQKIISLLSGKEEAIQLAVEELHQQHSKEIKELENLLSQEEEENVALEEENKRALEKTNQlteALEAIKKESF 2435
Cdd:PTZ00121  1614 ----KAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKK---AEEAKKAEED 1686

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2436 EQKAQldsfvksmsslqddrdriVSDYRQLEERHLSAILEKDQLIQDAAAENNKLKEEMRGLRSHMDDLNSENAKLDAEL 2515
Cdd:PTZ00121  1687 EKKAA------------------EALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEE 1748

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1720386946 2516 VQYRRDLNEVIAIKDSQQKQLLDAQLQQNKELRNECTKLEERLKGLEAEKQ 2566
Cdd:PTZ00121  1749 AKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKK 1799
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1311-2053 1.35e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 51.22  E-value: 1.35e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1311 IASELAKKSEEVLLLQDQINEQGLEIQNLKAASVEAQAHTELLKQELESSQlkvaglEHLKTLQPELDALHKHMGQKEEE 1390
Cdd:TIGR02169  292 VKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELE------REIEEERKRRDKLTEEYAELKEE 365

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1391 VNYLYGQLSEKEQTLTTVQTEMveqerliKALHTQLEMQAKEHEERLKQAQVEICELKKKPTELEEETNAKQQLQRKLqA 1470
Cdd:TIGR02169  366 LEDLRAELEEVDKEFAETRDEL-------KDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKI-N 437

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1471 ALISRKEALKEN--------KSLQEQLSSARDAVERLTKSLADVESQVSVQNQEKDAVLGKLTILQEERDKLIAEMDRFL 1542
Cdd:TIGR02169  438 ELEEEKEDKALEikkqewklEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLK 517

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1543 LENQSLSGSCESL-----------KLALGG-----LTEDKEKLMEELESVRSSKMAEST-----EWQEKHKELQKEYEVL 1601
Cdd:TIGR02169  518 ASIQGVHGTVAQLgsvgeryataiEVAAGNrlnnvVVEDDAVAKEAIELLKRRKAGRATflplnKMRDERRDLSILSEDG 597

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1602 L-----------QSYENVSNEAERIQHVVESVrQEKQELYAKLRSTESDKREREKqlQDAEQEMEEMKEKMRKFAKSKQQ 1670
Cdd:TIGR02169  598 VigfavdlvefdPKYEPAFKYVFGDTLVVEDI-EAARRLMGKYRMVTLEGELFEK--SGAMTGGSRAPRGGILFSRSEPA 674

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1671 KILELEEENDRLRAEAQPVGGTGESMEALLSSNSSLKEELEKitlEHKTLSKEFEALMAEKDALSEETRNLKLQveaqvL 1750
Cdd:TIGR02169  675 ELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASR---KIGEIEKEIEQLEQEEEKLKERLEELEED-----L 746

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1751 KQASLEATEKSDEPKDVIEEVTQAVVGKSQERDALSDsakLEDSEAilmgdgakpgvsetfsshddiknyLQQLDQLKGR 1830
Cdd:TIGR02169  747 SSLEQEIENVKSELKELEARIEELEEDLHKLEEALND---LEARLS------------------------HSRIPEIQAE 799

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1831 IAELEMEKQKDRELSQALENEKNALltqisakDSELKLLEEEvtkrttlnqqIQEELCRVTKLKETAEEEKDDLEerlmn 1910
Cdd:TIGR02169  800 LSKLEEEVSRIEARLREIEQKLNRL-------TLEKEYLEKE----------IQELQEQRIDLKEQIKSIEKEIE----- 857

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1911 qlaELNGSIGNYYQDVTDAQIKNEQLESEMRNLQRCVSELEEEKQQLVKEKTKVESEIRKEYMEKIQGAQKGPANKSHAK 1990
Cdd:TIGR02169  858 ---NLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELS 934

                          730       740       750       760       770       780
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1720386946 1991 ELQELLREKQQEV------KQLQKDCIRYLERISALEKTVKALEFVHTESQKDLDVTKGNLAQAVEHRK 2053
Cdd:TIGR02169  935 EIEDPKGEDEEIPeeelslEDVQAELQRVEEEIRALEPVNMLAIQEYEEVLKRLDELKEKRAKLEEERK 1003
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 2228-2747 1.37e-05

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 51.27  E-value: 1.37e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2228 HMEELKITVSRLEHD----KEIWESK----------AQTELQHHQKAYDKLQEENKELTSQLEDARQLYHDSKNELTKLE 2293
Cdd:pfam15921  318 QLSDLESTVSQLRSElreaKRMYEDKieelekqlvlANSELTEARTERDQFSQESGNLDDQLQKLLADLHKREKELSLEK 397

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2294 SELKSLKDQTTDLNNSLEKCKEHENNLEGIIKQQEADIQNCKFSCE-QLETDLAAsreltsrlhdeinakeqkiislLSG 2372
Cdd:pfam15921  398 EQNKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSECQgQMERQMAA----------------------IQG 455

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2373 KEEAIQlAVEELHQQHSKEIKELENLLSQEEEENVALEEENKRALEKTNQLTE---ALEAIKKESFEQKAQLDSFVKSMS 2449
Cdd:pfam15921  456 KNESLE-KVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEkerAIEATNAEITKLRSRVDLKLQELQ 534

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2450 SLQDDRDRIVSDYRQLEERHLSaILEKDQLIQDAAAENNKLKEEMRGLRSHMDDLNSENAKLDAELVQYRRDLNEVIAIK 2529
Cdd:pfam15921  535 HLKNEGDHLRNVQTECEALKLQ-MAEKDKVIEILRQQIENMTQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQEFKILK 613

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2530 DSQQKQLldaqlqqnKELRNECTKLE-ERLKGLEAEKQSLQMSSDaLQKEKQGLSKEIKNLQTQLTALQE---------- 2598
Cdd:pfam15921  614 DKKDAKI--------RELEARVSDLElEKVKLVNAGSERLRAVKD-IKQERDQLLNEVKTSRNELNSLSEdyevlkrnfr 684

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2599 ------EGTLGVYHAQLKAKEEELQRLNMALSSSQKRTADLEEELVCVQKEATRKVSEIeDQLKKELKHLHHDAGIMRNE 2672
Cdd:pfam15921  685 nkseemETTTNKLKMQLKSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQI-DALQSKIQFLEEAMTNANKE 763

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1720386946 2673 TETAEERVAELARDLVEMEQKLLTVTKENKDLMAQIQAFGRSMSSLQDSRDHATEELGDLKKKYDASLKELAQLK 2747
Cdd:pfam15921  764 KHFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANMEVALDKASLQFAECQDIIQRQEQESVRLK 838
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 2248-2903 1.44e-05

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 50.79  E-value: 1.44e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2248 SKAQTELQHHQKAYDKLQEENKELTSQLEDARQLYHDSKNELTKLESELKSLKDQTTDLNNSLEKCKEHENNLEGIIKQQ 2327
Cdd:TIGR04523   29 NKQDTEEKQLEKKLKTIKNELKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLNSDLSKI 108

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2328 EADIQNCKfsceqletdlaasreltsrlhDEINAKEQKIISLLSGKEEaiqlaVEELHQQHSKEIKELENLLsqeeeenv 2407
Cdd:TIGR04523  109 NSEIKNDK---------------------EQKNKLEVELNKLEKQKKE-----NKKNIDKFLTEIKKKEKEL-------- 154

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2408 aleeenkralektNQLTEALEAIKKESFEQKAQLDSFVKSMSSLQDDRDRIVSDYRQLEERhLSAILEKDQLIQDAAAEN 2487
Cdd:TIGR04523  155 -------------EKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKLELL-LSNLKKKIQKNKSLESQI 220

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2488 NKLKEEMRGLRSHMDDLNSENAKLDAELVQYRRDLNEVIAIKDSQQKQLLDAQlqqnkelrNECTKLEERLKGLEAEKQS 2567
Cdd:TIGR04523  221 SELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQ--------KELEQNNKKIKELEKQLNQ 292

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2568 LQMSSDALQKEKQ-----GLSKEIKNLQTQLTALQeegtlgvyhAQLKAKEEELQRLNMALSSSQKRTADLEEELVCVQK 2642
Cdd:TIGR04523  293 LKSEISDLNNQKEqdwnkELKSELKNQEKKLEEIQ---------NQISQNNKIISQLNEQISQLKKELTNSESENSEKQR 363

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2643 EATRKVSEIE------DQLKKELKHLHHDAGIMRNETETAEE---------RVAELARDLVEMEQKLLTVT-----KENK 2702
Cdd:TIGR04523  364 ELEEKQNEIEklkkenQSYKQEIKNLESQINDLESKIQNQEKlnqqkdeqiKKLQQEKELLEKEIERLKETiiknnSEIK 443

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2703 DLMAQIQAFGRSMSSLQDSRDHATEELGDLKKKYDASLKELAQLKewQDSSREGDVLSQAAFPLSTSENVLSRLEKLNQQ 2782
Cdd:TIGR04523  444 DLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQ--KELKSKEKELKKLNEEKKELEEKVKDLTKKISS 521

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2783 LTSKDEQLLHLSSELESSHNQVQSISKAMTS------LQNERDRLWSELEKFR---KSEEGKQRAAAPSAASSPAEVQSL 2853
Cdd:TIGR04523  522 LKEKIEKLESEKKEKESKISDLEDELNKDDFelkkenLEKEIDEKNKEIEELKqtqKSLKKKQEEKQELIDQKEKEKKDL 601

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2854 KKAMSSLQNDRDRLLKELKNLQQQYLQMSQEMTELRPLKAQLQESQDQTK 2903
Cdd:TIGR04523  602 IKEIEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIK 651
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 2770-3048 1.67e-05

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 50.71  E-value: 1.67e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2770 ENVLSRLEKLNQQLTSKDEQLLHLSSELESSHNQVQSISKAMTSLQNERDRLWSELEKFRKSEEGKQRaaapsaasspaE 2849
Cdd:COG1196    235 RELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQ-----------D 303

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2850 VQSLKKAMSSLQNDRDRLLKELKNLQQQYLQMSQEMTELRPLKAQLQESQDQTKALQVMEEELRQENLSWQHELRQLRME 2929
Cdd:COG1196    304 IARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEE 383

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2930 KNSWELHERRMKEQFLMAISDKDQQLGHLQSLLRELRSSSQAQILSTQYQRQASPETSASLDGSQKLVYETELLRTQLND 3009
Cdd:COG1196    384 LAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLE 463

                          250       260       270
                   ....*....|....*....|....*....|....*....
gi 1720386946 3010 SLKEIHQKELRIQQLNSKFSQLLEEKNVLSTQLSDASQS 3048
Cdd:COG1196    464 LLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEAD 502
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 1566-3069 1.68e-05

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 51.21  E-value: 1.68e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1566 KEKLMEELESVRSSKMAESTEWQEKHKELQKEYEV-------LLQSYENVSNEAERIQHVVESVRQEKQELYAKLRSTeS 1638
Cdd:TIGR01612  535 KAKLYKEIEAGLKESYELAKNWKKLIHEIKKELEEenedsihLEKEIKDLFDKYLEIDDEIIYINKLKLELKEKIKNI-S 613

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1639 DKREREKQLQDAEQEMEEMKEKMRKFAKSKQQKILELEEENDRL----RAEAQPVggTGESMEALLSSNSSLKEELEKIT 1714
Cdd:TIGR01612  614 DKNEYIKKAIDLKKIIENNNAYIDELAKISPYQVPEHLKNKDKIystiKSELSKI--YEDDIDALYNELSSIVKENAIDN 691

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1715 LEHKTlskEFEALMAEKDALSEETRNLklqvEAQVLKQASLEATEKSDEPKDVIEEVTQAVVGK-SQERDALsdsakLED 1793
Cdd:TIGR01612  692 TEDKA---KLDDLKSKIDKEYDKIQNM----ETATVELHLSNIENKKNELLDIIVEIKKHIHGEiNKDLNKI-----LED 759

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1794 seailmgdgAKPGVSETFSSHDDIKNYLQQLDQLKGRIAELE--------MEKQKDRELSQALENEKNALLTqISAKD-- 1863
Cdd:TIGR01612  760 ---------FKNKEKELSNKINDYAKEKDELNKYKSKISEIKnhyndqinIDNIKDEDAKQNYDKSKEYIKT-ISIKEde 829

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1864 -----SELKLLEEE----VTKRTTLNQQIQEELCR--------VTKLKETAEEEKDDLEERLMNQ----LAELNGSIGNY 1922
Cdd:TIGR01612  830 ifkiiNEMKFMKDDflnkVDKFINFENNCKEKIDSeheqfaelTNKIKAEISDDKLNDYEKKFNDskslINEINKSIEEE 909

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1923 YQDVTDAQIKNEQLE---------SEMRNLQRCVSELEEEKQQLVKEKTKVESEIRKEY----------MEKIQGAQKGP 1983
Cdd:TIGR01612  910 YQNINTLKKVDEYIKicentkesiEKFHNKQNILKEILNKNIDTIKESNLIEKSYKDKFdntlidkineLDKAFKDASLN 989

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1984 ANKSHAKELQELLREKQ------------QEVKQLQKDCIRYLERISALEKTVKALEFV-HTESQKDLDVTKGNLAQAVE 2050
Cdd:TIGR01612  990 DYEAKNNELIKYFNDLKanlgknkenmlyHQFDEKEKATNDIEQKIEDANKNIPNIEIAiHTSIYNIIDEIEKEIGKNIE 1069

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2051 HR-----KKAQAELSSFKIL--------LDDTQSEaarvlaDNLKLKKELQSNKESIKSQIKQKDEDL--LRRLEQAEEK 2115
Cdd:TIGR01612 1070 LLnkeilEEAEINITNFNEIkeklkhynFDDFGKE------ENIKYADEINKIKDDIKNLDQKIDHHIkaLEEIKKKSEN 1143

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2116 HRKEKKNMQEKLDALHREKAH---VEETLAEIQVSLTRKDQEmKELQGSLDSTLAQLAAFTKSMSSLQDDRD-------- 2184
Cdd:TIGR01612 1144 YIDEIKAQINDLEDVADKAISnddPEEIEKKIENIVTKIDKK-KNIYDEIKKLLNEIAEIEKDKTSLEEVKGinlsygkn 1222

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2185 ------RVIDEAKKWERRFGDAIQTKEEEV-RLKEENCIALKDQLRQMAIHMEelkITVSRLEHDKEiweSKAQTELQHH 2257
Cdd:TIGR01612 1223 lgklflEKIDEEKKKSEHMIKAMEAYIEDLdEIKEKSPEIENEMGIEMDIKAE---METFNISHDDD---KDHHIISKKH 1296

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2258 QKAYDKLQEENKELT------SQLEDARQLYHDSKNELTKLESELKSLKDQTTDLNNSLEKckeheNNLEGIIKQQEADI 2331
Cdd:TIGR01612 1297 DENISDIREKSLKIIedfseeSDINDIKKELQKNLLDAQKHNSDINLYLNEIANIYNILKL-----NKIKKIIDEVKEYT 1371

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2332 QNCKFSCEQLETDLAASRELTSRLHDEINAKE--QKIISLLSGKE--EAIQ---------LAVEELHQQHSKEIKEL-EN 2397
Cdd:TIGR01612 1372 KEIEENNKNIKDELDKSEKLIKKIKDDINLEEckSKIESTLDDKDidECIKkikelknhiLSEESNIDTYFKNADENnEN 1451

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2398 LL------------SQEEEENVALEEEN---------KRALEKTNQLTEALEAIKKESFEQKAQLDSFVKSMSSL----- 2451
Cdd:TIGR01612 1452 VLllfkniemadnkSQHILKIKKDNATNdhdfninelKEHIDKSKGCKDEADKNAKAIEKNKELFEQYKKDVTELlnkys 1531

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2452 -----------QDDRDRIVSDYRQLE----------ERHLSAILEKDQLIQDAAAENNKLKEEMRGLRSHMDDLNSENAK 2510
Cdd:TIGR01612 1532 alaiknkfaktKKDSEIIIKEIKDAHkkfileaeksEQKIKEIKKEKFRIEDDAAKNDKSNKAAIDIQLSLENFENKFLK 1611

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2511 LDaelvQYRRDLNEVIAIKDSQQKQL----LDAQLQQNKELRNECTKLEERLKGLEAEKQSLQMSsdalQKEKQGLSKEI 2586
Cdd:TIGR01612 1612 IS----DIKKKINDCLKETESIEKKIssfsIDSQDTELKENGDNLNSLQEFLESLKDQKKNIEDK----KKELDELDSEI 1683

                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2587 KNLQTQLTALQEEGTLGVYHA---QLKAKEEELQRLNMALSSSQKR------TADLEeelvcvQKEATRKVSEIEDQLKK 2657
Cdd:TIGR01612 1684 EKIEIDVDQHKKNYEIGIIEKikeIAIANKEEIESIKELIEPTIENlissfnTNDLE------GIDPNEKLEEYNTEIGD 1757

                         1290      1300      1310      1320      1330      1340      1350      1360
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2658 ELKHLHHDAGIMRNETET-AEERVA--ELARDLVEMEQKLLTVTKENKDLMA-----QIQAFGRSMSSLQDSRDHA---- 2725
Cdd:TIGR01612 1758 IYEEFIELYNIIAGCLETvSKEPITydEIKNTRINAQNEFLKIIEIEKKSKSylddiEAKEFDRIINHFKKKLDHVndkf 1837

                         1370      1380      1390      1400      1410      1420      1430      1440
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2726 TEELGDLKKKYDASLKELAQLKEWQDSSREGDVLSQaafplsTSENVLSRLEKLNQQLTSKDEQLLHLSSELESSHN-QV 2804
Cdd:TIGR01612 1838 TKEYSKINEGFDDISKSIENVKNSTDENLLFDILNK------TKDAYAGIIGKKYYSYKDEAEKIFINISKLANSINiQI 1911

                         1450      1460      1470      1480      1490      1500      1510      1520
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2805 QSiSKAMTSLQNERDRLWSELE-------KFRKSEEGKQRAAAPSAASSPAEVQSLKKAMSSLQNDRDRLLKELKNlQQQ 2877
Cdd:TIGR01612 1912 QN-NSGIDLFDNINIAILSSLDsekedtlKFIPSPEKEPEIYTKIRDSYDTLLDIFKKSQDLHKKEQDTLNIIFEN-QQL 1989

                         1530      1540      1550      1560      1570      1580      1590      1600
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2878 Y--LQMSQEMTE-LRPLKAQLQESQDQTKALQVMEEELRQENLSWQH--------ELRQLRMEKNSWELHERRMKEQFLM 2946
Cdd:TIGR01612 1990 YekIQASNELKDtLSDLKYKKEKILNDVKLLLHKFDELNKLSCDSQNydtilelsKQDKIKEKIDNYEKEKEKFGIDFDV 2069

                         1610      1620      1630      1640      1650      1660      1670      1680
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2947 AISDKdqqlgHLQSLLRELRSSSQAQILSTQYQRQASPETSASLDGSQKLVYETELLRTqlndslkEIHQKELRIQQLNS 3026
Cdd:TIGR01612 2070 KAMEE-----KFDNDIKDIEKFENNYKHSEKDNHDFSEEKDNIIQSKKKLKELTEAFNT-------EIKIIEDKIIEKND 2137

                         1690      1700      1710      1720
                   ....*....|....*....|....*....|....*....|....
gi 1720386946 3027 KFSQLLE-EKNVLSTQLSDASQSLRENQHHYSNLFNHCAILEKE 3069
Cdd:TIGR01612 2138 LIDKLIEmRKECLLFSYATLVETLKSKVINHSEFITSAAKFSKD 2181
46 PHA02562
endonuclease subunit; Provisional
 1817-1975 1.88e-05

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 50.40  E-value: 1.88e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1817 IKNYLQQLDQLKGRIAELEMEKQKDRELSQALENEKNALLTQISAKDSELKLLEEEVTKRTTLnQQIQEELCRVTKLKE- 1895
Cdd:PHA02562   229 AKTIKAEIEELTDELLNLVMDIEDPSAALNKLNTAAAKIKSKIEQFQKVIKMYEKGGVCPTCT-QQISEGPDRITKIKDk 307

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1896 --------TAEEEKDDLEERLMNQLA-------ELNGSIGNYYQDVTDAQIKNEQLESEMRNLQRCVSELEEEKQQLVKE 1960
Cdd:PHA02562   308 lkelqhslEKLDTAIDELEEIMDEFNeqskkllELKNKISTNKQSLITLVDKAKKVKAAIEELQAEFVDNAEELAKLQDE 387

                          170
                   ....*....|....*
gi 1720386946 1961 KTKVESEIRKEYMEK 1975
Cdd:PHA02562   388 LDKIVKTKSELVKEK 402
PTZ00121 PTZ00121
MAEBL; Provisional
 711-1521 1.89e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 50.91  E-value: 1.89e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  711 KEISSLTQLSEEVKESAEEARSTLAA-VTEERDQLLYQVKELDVLAELRARVQELESSLAEAEKQRgldyESQRAQHNLL 789
Cdd:PTZ00121  1084 KEDNRADEATEEAFGKAEEAKKTETGkAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAE----DAKRVEIARK 1159

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  790 TEQIHSLSIEAKSKDV-KIEALQReldGVQLQFCEQGTQMKTLQSQLEAKEREVREGTERLRDISQEmeglSQALSQKEL 868
Cdd:PTZ00121  1160 AEDARKAEEARKAEDAkKAEAARK---AEEVRKAEELRKAEDARKAEAARKAEEERKAEEARKAEDA----KKAEAVKKA 1232

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  869 EIAKMDQllLEKQKDVETLQQTIQEKDQQVTELSFSMTEKMVQLNEEKFSLGVEIKTLKEQLNLLSRTEEATKEQVEESG 948
Cdd:PTZ00121  1233 EEAKKDA--EEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKK 1310

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  949 AGSSLKLGHDESGQEGLQQELELLRKESEQRKRKLQAALINRKELLQKVSQLEEELAKVREDSRKEIPFGENERRKLEED 1028
Cdd:PTZ00121  1311 AEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEK 1390

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1029 RENRDDPEEWGTSKWREVEASLKQTISEKEVELegiRRDLKEKTAAEEELQAVVQRMTRDLQSKTKQIDLLQEEVTENQA 1108
Cdd:PTZ00121  1391 KKADEAKKKAEEDKKKADELKKAAAAKKKADEA---KKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAE 1467

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1109 TIQKLVTGTMDAGNGGSAAPVKETAassppgaggEEHWKPELEGRILDLEKDKTQLQKKLQEALIARKAilKKAQEKEKq 1188
Cdd:PTZ00121  1468 EAKKADEAKKKAEEAKKADEAKKKA---------EEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEA--KKAEEAKK- 1535

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1189 lKEELREQKDAYHHLQGQFHEQNKEkeniADQLRQLQCQARESIDRQLPGTGQQEpgppapslegisLEDTEPASESDLH 1268
Cdd:PTZ00121  1536 -ADEAKKAEEKKKADELKKAEELKK----AEEKKKAEEAKKAEEDKNMALRKAEE------------AKKAEEARIEEVM 1598

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1269 AAQPSPPGETAALQATVSVAQIQAQLKEMEVEKEELELKVSSIASELAKKSEEVlllQDQINEQGLEIQNLKAASVEAQA 1348
Cdd:PTZ00121  1599 KLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEEL---KKAEEENKIKAAEEAKKAEEDKK 1675

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1349 HTELLKQELESSQLKVaglEHLKTLQPEldalhkhmGQKEEEVnylygQLSEKEQTLTTVQTEMVEQERLIKAlhTQLEM 1428
Cdd:PTZ00121  1676 KAEEAKKAEEDEKKAA---EALKKEAEE--------AKKAEEL-----KKKEAEEKKKAEELKKAEEENKIKA--EEAKK 1737

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1429 QAKEHEERLKQAQVEICElKKKPTELEEETNAKQQLQRKLQAALIsrKEALKENKSLQeqlssaRDAVERLTKSLADVES 1508
Cdd:PTZ00121  1738 EAEEDKKKAEEAKKDEEE-KKKIAHLKKEEEKKAEEIRKEKEAVI--EEELDEEDEKR------RMEVDKKIKDIFDNFA 1808

                          810
                   ....*....|...
gi 1720386946 1509 QVSVQNQEKDAVL 1521
Cdd:PTZ00121  1809 NIIEGGKEGNLVI 1821
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
2249-2878 2.05e-05

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 50.45  E-value: 2.05e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2249 KAQTELQHHQKAYDKLQEENKELTSQLEDARQLYHDSKNELTKLESELKSLKDQTTDLNNSLEKCKEHENNLE---GIIK 2325
Cdd:PRK03918   162 NAYKNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEelkEEIE 241

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2326 QQEADIQNCKFSCEQLETDLAASRELTSRLHDEINAKEQKIISLLSGKEEAIQ-LAVEELHQQHSKEIKELENLLSQEEE 2404
Cdd:PRK03918   242 ELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKEKAEEyIKLSEFYEEYLDELREIEKRLSRLEE 321

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2405 ENVALeeenKRALEKTNQLTEALEAIKKESFEQKAQLDSFVKSMSSLQDDRdRIVSDYRQLEERhlsailEKDQLIQDAA 2484
Cdd:PRK03918   322 EINGI----EERIKELEEKEERLEELKKKLKELEKRLEELEERHELYEEAK-AKKEELERLKKR------LTGLTPEKLE 390

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2485 AENNKLKEEMRGLRSHMDDLNSENAKLDAELVQYRRDLNEVIAIK-----------DSQQKQLLDAQLQQNKELRNECTK 2553
Cdd:PRK03918   391 KELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKgkcpvcgreltEEHRKELLEEYTAELKRIEKELKE 470

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2554 LEERLKGLEAEKQSLQMssdALQKEKQGLSkeIKNLQTQLTALQEEgtLGVYHAQ-LKAKEEELQRLNMALSSSQKRTAD 2632
Cdd:PRK03918   471 IEEKERKLRKELRELEK---VLKKESELIK--LKELAEQLKELEEK--LKKYNLEeLEKKAEEYEKLKEKLIKLKGEIKS 543

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2633 LEEELVCVQ--KEATRKVSEIEDQLKKELKHLHHdagIMRNETETAEERVAELARDLVEMEQKLLTVtkenKDLMAQIQA 2710
Cdd:PRK03918   544 LKKELEKLEelKKKLAELEKKLDELEEELAELLK---ELEELGFESVEELEERLKELEPFYNEYLEL----KDAEKELER 616

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2711 FGRSMSSLQDSRDHATEELGDLKKKYDASLKELAQLKEWQDSSRegdvlsqaafplstsenvlsrLEKLNQQLTSKDEQL 2790
Cdd:PRK03918   617 EEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEEE---------------------YEELREEYLELSREL 675

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2791 LHLSSELESSHNQVQSISKAMTSLQNERDrlwsELEKFRKseegkqraaapsaasspaEVQSLKKAMSSLQNDRDRlLKE 2870
Cdd:PRK03918   676 AGLRAELEELEKRREEIKKTLEKLKEELE----EREKAKK------------------ELEKLEKALERVEELREK-VKK 732


                   ....*...
gi 1720386946 2871 LKNLQQQY 2878
Cdd:PRK03918   733 YKALLKER 740
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 2206-2955 2.98e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 50.07  E-value: 2.98e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2206 EEVRLKEENCIALKDQLRQmaiHMEELKITVSRLEHDKEIWESKAQTELQHHQKAYDKLQEENKELTSQLEDARQLYHDS 2285
Cdd:TIGR02169  180 EEVEENIERLDLIIDEKRQ---QLERLRREREKAERYQALLKEKREYEGYELLKEKEALERQKEAIERQLASLEEELEKL 256

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2286 KNELTKLESELKSLKDQTTDLNNSLEKCKEHE-NNLEGIIKQQEADIQNCKFSCEQLETDLAASRELTSRLHDEINAKEQ 2364
Cdd:TIGR02169  257 TEEISELEKRLEEIEQLLEELNKKIKDLGEEEqLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLA 336

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2365 KIISLlSGKEEAIQLAVEELhqqhSKEIKELENLLSQEEEENVALEEENKRALEKTNQLTEALEAIKKEsfeqkaqldsf 2444
Cdd:TIGR02169  337 EIEEL-EREIEEERKRRDKL----TEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKRE----------- 400

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2445 vksMSSLQDDRDRIVSDYRQLEERhlsaILEKDQLIQDAAAENNKLKEEMRGLRshmddlnsenakldAELVQYRRDLNE 2524
Cdd:TIGR02169  401 ---INELKRELDRLQEELQRLSEE----LADLNAAIAGIEAKINELEEEKEDKA--------------LEIKKQEWKLEQ 459

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2525 VIAIKDSQQKQLLDAQLQQNKeLRNECTKLEERLKGLEAEKQSL---QMSSDALQKEKQGLSKEIKNLQTQLTALQEEGT 2601
Cdd:TIGR02169  460 LAADLSKYEQELYDLKEEYDR-VEKELSKLQRELAEAEAQARASeerVRGGRAVEEVLKASIQGVHGTVAQLGSVGERYA 538

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2602 LGVYHA---QLKA----------------KEEELQRLN-MALSSSQKRTADLEEELVCVQKEATRKVSEIEDQLKKELKH 2661
Cdd:TIGR02169  539 TAIEVAagnRLNNvvveddavakeaiellKRRKAGRATfLPLNKMRDERRDLSILSEDGVIGFAVDLVEFDPKYEPAFKY 618

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2662 LHHDAGIMRNeTETAEE-----RVAELARDLVE----------MEQKLLTVTKENKD----LMAQIQAFGRSMSSLQDSR 2722
Cdd:TIGR02169  619 VFGDTLVVED-IEAARRlmgkyRMVTLEGELFEksgamtggsrAPRGGILFSRSEPAelqrLRERLEGLKRELSSLQSEL 697

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2723 DHATEELGDLKKKYDASLKELAQL-KEWQDSSREGDVLSQAAfplstsENVLSRLEKLNQQLTSKDEQLLHLSSELESSH 2801
Cdd:TIGR02169  698 RRIENRLDELSQELSDASRKIGEIeKEIEQLEQEEEKLKERL------EELEEDLSSLEQEIENVKSELKELEARIEELE 771

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2802 NQVQSISKAMTSLQNERDRlwselEKFRKSEEgKQRAAAPSAASSPAEVQSLKKAMSSLQNDRDRLLKELKNLQQQylqm 2881
Cdd:TIGR02169  772 EDLHKLEEALNDLEARLSH-----SRIPEIQA-ELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQ---- 841

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1720386946 2882 sqemteLRPLKAQLQESQDQTKALQVMEEELRQENLSWQHELRQLRMEKNSWELHERRMKEQfLMAISDKDQQL 2955
Cdd:TIGR02169  842 ------RIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQ-LRELERKIEEL 908
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1807-2548 3.19e-05

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 50.12  E-value: 3.19e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1807 VSETFSSHDDIKNYLQQ-LDQLKGRIAELEMEKQK----DRELSQALENEKNALLTQISAKDSELKLLEEEVTKRTTLNQ 1881
Cdd:pfam15921   94 LNESNELHEKQKFYLRQsVIDLQTKLQEMQMERDAmadiRRRESQSQEDLRNQLQNTVHELEAAKCLKEDMLEDSNTQIE 173

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1882 QIQEELCRVTKLKETAEEEKDDLEERLMNQLAELNGSIGNYYQDVTDAQIKN-EQLESEMRNLQRCVSELEEEKQQLVKE 1960
Cdd:pfam15921  174 QLRKMMLSHEGVLQEIRSILVDFEEASGKKIYEHDSMSTMHFRSLGSAISKIlRELDTEISYLKGRIFPVEDQLEALKSE 253

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1961 ------------KTKVESEIRKEYMEKIQGAQKGPANKSHAKELQELLREKQQEVKQLQKdciRYLERISALEKTVKALE 2028
Cdd:pfam15921  254 sqnkielllqqhQDRIEQLISEHEVEITGLTEKASSARSQANSIQSQLEIIQEQARNQNS---MYMRQLSDLESTVSQLR 330

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2029 FVHTESQK----DLDVTKGNLAQAVEHRKKAQAELSSFKILLDDTQSEAARVLADNLKLKKELQSNKESIKsqiKQKDED 2104
Cdd:pfam15921  331 SELREAKRmyedKIEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLADLHKREKELSLEKEQNK---RLWDRD 407

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2105 LLRRLEQAEEKHRKEKKNMQekldaLHREKAHVEETLAEIQVSLtrkDQEMKELQGSlDSTLAQLAAFTKSMSSLQDDRD 2184
Cdd:pfam15921  408 TGNSITIDHLRRELDDRNME-----VQRLEALLKAMKSECQGQM---ERQMAAIQGK-NESLEKVSSLTAQLESTKEMLR 478

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2185 RVIDE--AKKW-----ERRFGD---AIQTKEEEVRLKEENCIALK-----------------DQLRQMAIHMEELKITVS 2237
Cdd:pfam15921  479 KVVEEltAKKMtlessERTVSDltaSLQEKERAIEATNAEITKLRsrvdlklqelqhlknegDHLRNVQTECEALKLQMA 558

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2238 RLEHDKEIWESKAQTELQ---HHQKAYDKLQEENKELTSQLEDARQLYHDSKNELTKLESELKSLKDQTTDLnnSLEKCK 2314
Cdd:pfam15921  559 EKDKVIEILRQQIENMTQlvgQHGRTAGAMQVEKAQLEKEINDRRLELQEFKILKDKKDAKIRELEARVSDL--ELEKVK 636

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2315 ehennLEGIIKQQEADIQNCKFSCEQLETDLAASRELTSRLHDEINAKEQKiislLSGKEEAIQLAVEELHQQHSKEIKE 2394
Cdd:pfam15921  637 -----LVNAGSERLRAVKDIKQERDQLLNEVKTSRNELNSLSEDYEVLKRN----FRNKSEEMETTTNKLKMQLKSAQSE 707

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2395 LENLLSQEEEENVALEEENKRALEKTNQLTEaleaikkesfeQKAQLDSFVKSMSSLQDDRDRIVSDYRQLEErhlsail 2474
Cdd:pfam15921  708 LEQTRNTLKSMEGSDGHAMKVAMGMQKQITA-----------KRGQIDALQSKIQFLEEAMTNANKEKHFLKE------- 769

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1720386946 2475 EKDQLIQD---AAAENNKLKEEMRGLRSHMDDLNSENAKLDAELVQYRRDLNEVIAIKDSQQKQLLDAQLQQNKELR 2548
Cdd:pfam15921  770 EKNKLSQElstVATEKNKMAGELEVLRSQERRLKEKVANMEVALDKASLQFAECQDIIQRQEQESVRLKLQHTLDVK 846
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 1424-2240 3.43e-05

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 50.05  E-value: 3.43e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1424 TQLEMQAKEHEERLKQAQVEICELKKKPTELEEETNAKQQLQRKLQAALISRKEALKENKSLQEQL-------------- 1489
Cdd:TIGR00606  227 TSKEAQLESSREIVKSYENELDPLKNRLKEIEHNLSKIMKLDNEIKALKSRKKQMEKDNSELELKMekvfqgtdeqlndl 306

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1490 -----SSARDAVERLT---KSLADVESQVSVQNQEKDAVLGKLTILQEERDKLIAEMDRFLLENQSLSGSCESLKLALGG 1561
Cdd:TIGR00606  307 yhnhqRTVREKERELVdcqRELEKLNKERRLLNQEKTELLVEQGRLQLQADRHQEHIRARDSLIQSLATRLELDGFERGP 386

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1562 LTEDKEKLMEELESVRSSKMAES------------TEWQEKHKELQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQEL 1629
Cdd:TIGR00606  387 FSERQIKNFHTLVIERQEDEAKTaaqlcadlqskeRLKQEQADEIRDEKKGLGRTIELKKEILEKKQEELKFVIKELQQL 466

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1630 YAKLRSTESDKREREKQLQDAEQEME----EMKEKMRKFAKSKQQKILELEEENDRLRAEAQPVGGTGESMEALLSSNSS 1705
Cdd:TIGR00606  467 EGSSDRILELDQELRKAERELSKAEKnsltETLKKEVKSLQNEKADLDRKLRKLDQEMEQLNHHTTTRTQMEMLTKDKMD 546

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1706 LKEELEKITLEH--------------KTLSKEFEALMAEKDALSEETRNLKLQVEAQVLKQASLEATEKSDEPKDV---- 1767
Cdd:TIGR00606  547 KDEQIRKIKSRHsdeltsllgyfpnkKQLEDWLHSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSsyed 626

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1768 --------------IEEVTQAVVGKSQERDALSDSAKLEDS---EAILMGDGAKPGVSETFSSHDDIKNYLQQLdQLKGR 1830
Cdd:TIGR00606  627 klfdvcgsqdeesdLERLKEEIEKSSKQRAMLAGATAVYSQfitQLTDENQSCCPVCQRVFQTEAELQEFISDL-QSKLR 705

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1831 IAELEMEKQKdrELSQALENEKNALLTQISAKDSELKLLEEEVTKRTTLNQQIQEELCRVTKLKETAEEEKDDL--EERL 1908
Cdd:TIGR00606  706 LAPDKLKSTE--SELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTImpEEES 783

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1909 MNQLAELNGSIGNYYQDVTDAQIKNEQLESEMR--NLQRCVSELEEEKQQLVKEKTKVESEIR------KEYMEKIQGAQ 1980
Cdd:TIGR00606  784 AKVCLTDVTIMERFQMELKDVERKIAQQAAKLQgsDLDRTVQQVNQEKQEKQHELDTVVSKIElnrkliQDQQEQIQHLK 863

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1981 -KGPANKSHAKELQELLREKQQEVKQLQKDCIRYLERISALEKTVKALEFVHTESQKDLDVTKGNLAQAVEHRKKAQAEl 2059
Cdd:TIGR00606  864 sKTNELKSEKLQIGTNLQRRQQFEEQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEELISSKETSNKKAQDK- 942

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2060 ssfkilLDDTQSEAARVLADNLKLKKELQSNKESIKSQIKQKDEDLLRRLEQAEEKHRKEKKNMQEKLDALhrEKAHVEE 2139
Cdd:TIGR00606  943 ------VNDIKEKVKNIHGYMKDIENKIQDGKDDYLKQKETELNTVNAQLEECEKHQEKINEDMRLMRQDI--DTQKIQE 1014

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2140 TLAEIQVSLTRKDQEMKELQGSLDSTLAQLA-----AFTKSMSSLQDDRDRV-IDEAKKWERRFGDAIQTKEEEVRLKEE 2213
Cdd:TIGR00606 1015 RWLQDNLTLRKRENELKEVEEELKQHLKEMGqmqvlQMKQEHQKLEENIDLIkRNHVLALGRQKGYEKEIKHFKKELREP 1094

                          890       900
                   ....*....|....*....|....*..
gi 1720386946 2214 NCIALKDQLRQMAIHMEELKITVSRLE 2240
Cdd:TIGR00606 1095 QFRDAEEKYREMMIVMRTTELVNKDLD 1121
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2386-2599 3.71e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 48.99  E-value: 3.71e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2386 QQHSKEIKELENLLSQEEEENVALEEENKRALEKTNQLTEALEAIKKESFEQKAQLDSFVKSMSSLQDDRD--------R 2457
Cdd:COG4942     30 EQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEaqkeelaeL 109

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2458 IVSDYRQLEERHLSAILEKDQlIQDAAAENNKLKEEMRGLRSHMDDLNSENAKLdaelvqyrRDLNEVIAIKDSQQKQLL 2537
Cdd:COG4942    110 LRALYRLGRQPPLALLLSPED-FLDAVRRLQYLKYLAPARREQAEELRADLAEL--------AALRAELEAERAELEALL 180

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1720386946 2538 DAQLQQNKELRNECTKLEERLKGLEAEKQSLQMSSDALQKEKQGLSKEIKNLQTQLTALQEE 2599
Cdd:COG4942    181 AELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1149-1625 4.18e-05

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 49.65  E-value: 4.18e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1149 ELEGRILDLEKDKTQLQKKLQEAliarKAILKKAQEKekqlKEELREQKDAYHHLQGQFHEQNKEKENIADQLRQLQCQA 1228
Cdd:PRK02224   217 ELDEEIERYEEQREQARETRDEA----DEVLEEHEER----REELETLEAEIEDLRETIAETEREREELAEEVRDLRERL 288

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1229 ---RESIDRQLPGTGQQEPGPPAPSLEGISLEDTEPASESDLHAAQPSPPG-ETAALQATVSVAQIQAQLKEMEVEKEEL 1304
Cdd:PRK02224   289 eelEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQAhNEEAESLREDADDLEERAEELREEAAEL 368

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1305 ELKVSSIASELAKKSEEVLLLQDQINEQGLEIQNLKAASVEAQAHTELLKQELESSQLKVAGLE-HLKTL---------- 1373
Cdd:PRK02224   369 ESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAELEaTLRTArerveeaeal 448

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1374 ----------QPELDALH-KHMGQKEEEVNYLYGQLSEKEQTLTTVQ------TEMVEQERLIKALHTQLEMQAK---EH 1433
Cdd:PRK02224   449 leagkcpecgQPVEGSPHvETIEEDRERVEELEAELEDLEEEVEEVEerleraEDLVEAEDRIERLEERREDLEEliaER 528

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1434 EERLKQAQVEICELKKKPTELEEETNAKQQLQRKLQAALISRKEALKENKSLQEQLSSARDAVERLTKSLADVES--QVS 1511
Cdd:PRK02224   529 RETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESLERIRTLLAAIADaeDEI 608

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1512 VQNQEKDAVLG--------KLTILQEERDKLIAEMDRFLLEN-----QSLSGSCESLKLALGGLTEDKEKLMEELESVRS 1578
Cdd:PRK02224   609 ERLREKREALAelnderreRLAEKRERKRELEAEFDEARIEEaredkERAEEYLEQVEEKLDELREERDDLQAEIGAVEN 688

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|....*..
gi 1720386946 1579 SkMAESTEWQEKHKELQKEYEVLlqsyENVSNEAERIQHVVESVRQE 1625
Cdd:PRK02224   689 E-LEELEELRERREALENRVEAL----EALYDEAEELESMYGDLRAE 730
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1602-2266 4.18e-05

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 49.68  E-value: 4.18e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1602 LQSYENVSNEAERIQHVVESVRQEKQELYAKLRSTESDKREREKQLQDAEQEMeemkekmrkfaKSKQQKILELEEENDR 1681
Cdd:PRK03918   157 LDDYENAYKNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREI-----------NEISSELPELREELEK 225

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1682 LRAEaqpvggtgesmeallssnsslKEELEKITLEHKTLSKEFEALMAEKDALSEETRNLKLQVEAQVLKQASLEatEKS 1761
Cdd:PRK03918   226 LEKE---------------------VKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELE--EKV 282

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1762 DEPKDVIEEVTQAVVGKSQERDALSDSAKLEDSEAILMgdgakpgvsetfSSHDDIKNYLQQLDQLKGRIAELEMEKQKD 1841
Cdd:PRK03918   283 KELKELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLE------------EEINGIEERIKELEEKEERLEELKKKLKEL 350

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1842 RELSQALEnEKNALLTQISAKDSELKLLEEEVTKRTTlnQQIQEELCRVTKLKETAEEEKDDLEERlmnqlaelngsIGN 1921
Cdd:PRK03918   351 EKRLEELE-ERHELYEEAKAKKEELERLKKRLTGLTP--EKLEKELEELEKAKEEIEEEISKITAR-----------IGE 416

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1922 YYQDVTDAQIKNEQLESEMRNLQRCVSEL-EEEKQQLVKEKTKVESEIRKEymekiqgaqkgpankshAKELQELLREKQ 2000
Cdd:PRK03918   417 LKKEIKELKKAIEELKKAKGKCPVCGRELtEEHRKELLEEYTAELKRIEKE-----------------LKEIEEKERKLR 479

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2001 QEVKQLQKDcIRYLERISALEKTVKALEFVHTESQKdldvtkgnlaQAVEHRKKAQAELSSFKILLDDTQSEaARVLADN 2080
Cdd:PRK03918   480 KELRELEKV-LKKESELIKLKELAEQLKELEEKLKK----------YNLEELEKKAEEYEKLKEKLIKLKGE-IKSLKKE 547

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2081 LKLKKELQSNKESIKSQIKQKDEDLLRRLEQAEEKHRKEKKNMQEKLDALhrEKAHVEE-TLAEIQVSLTRKDQEMKELQ 2159
Cdd:PRK03918   548 LEKLEELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERLKEL--EPFYNEYlELKDAEKELEREEKELKKLE 625

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2160 GSLDSTLAQLAAFTKSMSSLQDDrdrvIDEAKKweRRFGDAIQTKEEEVRLKEENCIALKDQLRQMAIHMEELKITVSRL 2239
Cdd:PRK03918   626 EELDKAFEELAETEKRLEELRKE----LEELEK--KYSEEEYEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKL 699

                          650       660
                   ....*....|....*....|....*..
gi 1720386946 2240 EHDKEIWEsKAQTELQHHQKAYDKLQE 2266
Cdd:PRK03918   700 KEELEERE-KAKKELEKLEKALERVEE 725
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 123-367 4.22e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 48.99  E-value: 4.22e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  123 AALPPEAQAEELSKHNKSSTEEEMEIEKIKHELQEKEKLISSLQAQLDQSEQasQLDKSSAEMEDfvlMKQQLQEKEELI 202
Cdd:COG4942     11 LALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALER--RIAALARRIRA---LEQELAALEAEL 85

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  203 STLQTQLSQTQAEQAAQvVREKDARFETQVRLHEDELLQLVTQSDVETEMQQKLRVMQRKLEEHEEallgRAQVVDLLQK 282
Cdd:COG4942     86 AELEKEIAELRAELEAQ-KEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARRE----QAEELRADLA 160

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  283 ELTSAEQRNQVLSQQLQLLEAEHNTLKNTMETERQESKTLMEKVELEVAERKLSFHNLQEEMHQLQGQLERAGQAQADLE 362
Cdd:COG4942    161 ELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAA 240


                   ....*
gi 1720386946  363 TQYSA 367
Cdd:COG4942    241 ERTPA 245
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
2473-2730 4.31e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 49.53  E-value: 4.31e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2473 ILEKDQLIQDAAAennkLKEEMRGLRSHMDDLNSENAKLDA--ELVQYRRDLNEVIAIKDSQQKQLLDAQLQQNKE---- 2546
Cdd:COG4913    217 MLEEPDTFEAADA----LVEHFDDLERAHEALEDAREQIELlePIRELAERYAAARERLAELEYLRAALRLWFAQRrlel 292

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2547 LRNECTKLEERLKGLEAEKQSLQMSSDALQKEKQGLSKEIKNLQTQ-LTALQEEgtlgvyhaqLKAKEEELQRLNMALSS 2625
Cdd:COG4913    293 LEAELEELRAELARLEAELERLEARLDALREELDELEAQIRGNGGDrLEQLERE---------IERLERELEERERRRAR 363

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2626 SQKRTADLEEELVCVQKEATRKVSEIEDQLkkelkhlhhdagimrnetETAEERVAELARDLVEMEQKLLTVTKENKDLM 2705
Cdd:COG4913    364 LEALLAALGLPLPASAEEFAALRAEAAALL------------------EALEEELEALEEALAEAEAALRDLRRELRELE 425

                          250       260
                   ....*....|....*....|....*....
gi 1720386946 2706 AQIQAFGRSMSS----LQDSRDHATEELG 2730
Cdd:COG4913    426 AEIASLERRKSNiparLLALRDALAEALG 454
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1142-2008 4.36e-05

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 49.58  E-value: 4.36e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1142 GEEHWKPELEGRILDLEKDKTQLQKKLQEALIARKAILKKAQEKEKQLKEELREQKDAYHHLQGQFHEQNKEKENIADQL 1221
Cdd:pfam02463  152 PERRLEIEEEAAGSRLKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDY 231

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1222 RQLQCQARESIDRQLPGTGQQEPGPPAPSLEGISLEDTEPASESDLHAAQPSppGETAALQATVSVAQIQAQLKEMEVEK 1301
Cdd:pfam02463  232 LKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKL--QEEELKLLAKEEEELKSELLKLERRK 309

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1302 EELELKVSSIASELAKKSEEVLLLQDQINEQGLEIQNLKAASveaqahTELLKQELESSQLKVAGLEHLKTLQPELDALH 1381
Cdd:pfam02463  310 VDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKR------EAEEEEEEELEKLQEKLEQLEEELLAKKKLES 383

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1382 KHMGQKEEEVNYLYGQLSEKEQTLTTVQTEMVEQERLIKALHTQLEMQAKEhEERLKQAQVEICELKKKPTELEEETNAK 1461
Cdd:pfam02463  384 ERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEE-EEESIELKQGKLTEEKEELEKQELKLLK 462

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1462 QQLQRKLQAALISRKEALKENKSLQEQLSSARDAvERLTKSLADVESQVSVQNQEKDAVLGKLTILQEERDKLIAEMDRF 1541
Cdd:pfam02463  463 DELELKKSEDLLKETQLVKLQEQLELLLSRQKLE-ERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENY 541

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1542 LLENQSL-----------SGSCESLKLALGGLTEDKEKLMEELESVRSSKMAESTEWQEKHKELQKEYEVLLQSYENVSN 1610
Cdd:pfam02463  542 KVAISTAvivevsatadeVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKR 621

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1611 EAERIQHVVESVRQEKQELYAKLRSTESDKREREKQLQDAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEAQPVG 1690
Cdd:pfam02463  622 AKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEI 701

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1691 GTGESMEALLSSNSSLKEE---LEKITLEHKTLSKEFEALMAEKDALSEETRNLKLQVEAQVLKQASLEATEKSDEPKDV 1767
Cdd:pfam02463  702 KKKEQREKEELKKLKLEAEellADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEERE 781

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1768 IEEVtqavvgKSQERDALSDSAKLEDSEAILMgdgakpgvsetfsSHDDIKNYLQQLDQLKGRIAELEMEKQKDRELSQA 1847
Cdd:pfam02463  782 KTEK------LKVEEEKEEKLKAQEEELRALE-------------EELKEEAELLEEEQLLIEQEEKIKEEELEELALEL 842

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1848 LENEKNALLTQISAKDSELKLLEEEVTKRTTLNQQIQEELCRVTKLKETAEEEKDDLEERLMNQLAELNgsiGNYYQDVT 1927
Cdd:pfam02463  843 KEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKLNL---LEEKENEI 919

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1928 DAQIKNEQLESEMRNLQRCVSELEEEKQQLVKEKTKVESEIRKEYMEKiQGAQKGPANKSHAKELQELLREKQQEVKQLQ 2007
Cdd:pfam02463  920 EERIKEEAEILLKYEEEPEELLLEEADEKEKEENNKEEEEERNKRLLL-AKEELGKVNLMAIEEFEEKEERYNKDELEKE 998


                   .
gi 1720386946 2008 K 2008
Cdd:pfam02463  999 R 999
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1982-2196 4.57e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 48.61  E-value: 4.57e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1982 GPANKSHAKELQELLREKQQEVKQLQKDCIRYLERISALEKTVKALEFVHTESQKDLDVTKGNLAQAVEHRKKAQAELSS 2061
Cdd:COG4942     15 AAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAE 94

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2062 FKILLDDTQSEAARVLA--------DNLKLKKELQSNKESIKS-----QIKQKDEDLLRRLEQAEEKHRKEKKNMQEKLD 2128
Cdd:COG4942     95 LRAELEAQKEELAELLRalyrlgrqPPLALLLSPEDFLDAVRRlqylkYLAPARREQAEELRADLAELAALRAELEAERA 174

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1720386946 2129 ALHREKAHVEETLAEIQVSLTRKDQEMKELQGSLDSTLAQLAAFTKSMSSLQDDRDRVIDEAKKWERR 2196
Cdd:COG4942    175 ELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 2471-3051 4.84e-05

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 49.45  E-value: 4.84e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2471 SAILEKDQLIQDAAAENNKLKEEMRGLRSHM----DDLNSENAKLDAELVQYRRDLNEViaikDSQQKQLLDAQLQQNK- 2545
Cdd:pfam12128  269 SDETLIASRQEERQETSAELNQLLRTLDDQWkekrDELNGELSAADAAVAKDRSELEAL----EDQHGAFLDADIETAAa 344

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2546 ------ELRNECTKLEERLKGLEAEKQSLQMSSDAL-QKEKQGLSKEIKNLQTQLTALQEEGTLG------VYHAQLKAK 2612
Cdd:pfam12128  345 dqeqlpSWQSELENLEERLKALTGKHQDVTAKYNRRrSKIKEQNNRDIAGIKDKLAKIREARDRQlavaedDLQALESEL 424

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2613 EEELQRLNMALSSSQKRTADLEEELVCVQKEATRKVSEIEDQLKK--ELKHLHHDAGIMRNETETA--EERVAELARD-- 2686
Cdd:pfam12128  425 REQLEAGKLEFNEEEYRLKSRLGELKLRLNQATATPELLLQLENFdeRIERAREEQEAANAEVERLqsELRQARKRRDqa 504

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2687 ---LVEMEQKLLTVTKENKDLMAQIqaFGRSMSSLQDSRDHATEELGDLKKKYDASLKELAQLKEWQDSSREGDVLSQAA 2763
Cdd:pfam12128  505 seaLRQASRRLEERQSALDELELQL--FPQAGTLLHFLRKEAPDWEQSIGKVISPELLHRTDLDPEVWDGSVGGELNLYG 582

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2764 FPLSTSENVLSRLEKLNQQLTSKDEQllhLSSELESSHNQVQSISKAMTSLQNERDRLWSELEkfrkseegkqraaapsa 2843
Cdd:pfam12128  583 VKLDLKRIDVPEWAASEEELRERLDK---AEEALQSAREKQAAAEEQLVQANGELEKASREET----------------- 642

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2844 asspaevqslkKAMSSLQNDRDRlLKELKNLQQQYLQMSQEMTELRPLKAQlQESQDQTKALQVMEEELRQENLSWQHEL 2923
Cdd:pfam12128  643 -----------FARTALKNARLD-LRRLFDEKQSEKDKKNKALAERKDSAN-ERLNSLEAQLKQLDKKHQAWLEEQKEQK 709

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2924 RQLRMEKNswelherrmkEQFLMAISDKDQQLGHLQSLLRELRSSSQAQI--LSTQYQRQAspetsASLDGSQKLVYETE 3001
Cdd:pfam12128  710 REARTEKQ----------AYWQVVEGALDAQLALLKAAIAARRSGAKAELkaLETWYKRDL-----ASLGVDPDVIAKLK 774

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1720386946 3002 LLRTQLNDSLKEIHQKELRIQQLNSKF-SQLLEEKNVLSTQLSDASQSLRE 3051
Cdd:pfam12128  775 REIRTLERKIERIAVRRQEVLRYFDWYqETWLQRRPRLATQLSNIERAISE 825
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1335-1754 5.23e-05

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 49.00  E-value: 5.23e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1335 EIQNLKAASVEAQAHTELLKQELESSQLKVAGLEHLKTLQPELDALHKHmGQKEEEVNYLYGQLSEKEQTLTTVQTEMVE 1414
Cdd:COG4717     89 EYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEAL-EAELAELPERLEELEERLEELRELEEELEE 167

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1415 QERLIKALHTQLEMQAK----EHEERLKQAQVEICELKKKPTELEEETNAKQQLQRKLQAA---LISRKEALKENKSLQE 1487
Cdd:COG4717    168 LEAELAELQEELEELLEqlslATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEEleqLENELEAAALEERLKE 247

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1488 QLSSARDAVERLTKSLADVESQVSVQNQEKDAVLG-------------KLTILQEERDKLIAEMDRFLLENQSLSGSCES 1554
Cdd:COG4717    248 ARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVlgllallflllarEKASLGKEAEELQALPALEELEEEELEELLAA 327

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1555 LKLALGGLTEDKEKLMEELESVRSS-KMAESTEWQEKHKELQKEYEVLLQSYeNVSNEAERIQHVVESvrQEKQELYAKL 1633
Cdd:COG4717    328 LGLPPDLSPEELLELLDRIEELQELlREAEELEEELQLEELEQEIAALLAEA-GVEDEEELRAALEQA--EEYQELKEEL 404

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1634 RSTESDKREREKQLQDAEQEMEEMKEKMRkfAKSKQQKILELEEENDRLRAEaqpVGGTGESMEALLSSN--SSLKEELE 1711
Cdd:COG4717    405 EELEEQLEELLGELEELLEALDEEELEEE--LEELEEELEELEEELEELREE---LAELEAELEQLEEDGelAELLQELE 479

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|...
gi 1720386946 1712 KITLEHKTLSKEFEALMAEKDALSEETRNLKLQVEAQVLKQAS 1754
Cdd:COG4717    480 ELKAELRELAEEWAALKLALELLEEAREEYREERLPPVLERAS 522
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2418-2636 6.52e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 48.22  E-value: 6.52e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2418 EKTNQLTEALEAIKKESFEQKAQLDSFVKSMSSLQDDRDRIVSDYRQLEERhlsailekdqlIQDAAAENNKLKEEMRGL 2497
Cdd:COG4942     27 AELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQE-----------LAALEAELAELEKEIAEL 95

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2498 RSHMDDLNSENAKLDAELVQYRR--DLNEVIAIKDSQQ--------KQLLDAQLQQNKELRNECTKLEERLKGLEAEKQS 2567
Cdd:COG4942     96 RAELEAQKEELAELLRALYRLGRqpPLALLLSPEDFLDavrrlqylKYLAPARREQAEELRADLAELAALRAELEAERAE 175

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1720386946 2568 LQMSSDALQKEKQGLSKEIKNLQTQLTALQEEgtLGVYHAQLKAKEEELQRLNMALSSSQKRTADLEEE 2636
Cdd:COG4942    176 LEALLAELEEERAALEALKAERQKLLARLEKE--LAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1579-2148 8.07e-05

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 48.50  E-value: 8.07e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1579 SKMAESTEwQEKHKELQKEYEVllqsyeNVSNEAERIQHVVESVRQEKQELYAKLRSTESDKREREKQLQDAEQEmeemk 1658
Cdd:PRK02224   213 SELAELDE-EIERYEEQREQAR------ETRDEADEVLEEHEERREELETLEAEIEDLRETIAETEREREELAEE----- 280

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1659 ekmrkfAKSKQQKILELEEENDRLRAEAQPVGGTGESMEALLSSNSSLKEELEKITLEHKTLSKEF--EALMAEKDALSE 1736
Cdd:PRK02224   281 ------VRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQAHneEAESLREDADDL 354

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1737 ETRNLKLQVEAQVLKQASLEATEKSDEPKDVIEEVtqavvgksqERDALSDSAKLEDSEAILmgDGAKPGVSETFSSHDD 1816
Cdd:PRK02224   355 EERAEELREEAAELESELEEAREAVEDRREEIEEL---------EEEIEELRERFGDAPVDL--GNAEDFLEELREERDE 423

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1817 IKNYLQQLD----QLKGRIAELE--MEKQKDRELSQALENEKNAllTQISAKDSELKLLEEEVTKRTTLNQQIQEELCRV 1890
Cdd:PRK02224   424 LREREAELEatlrTARERVEEAEalLEAGKCPECGQPVEGSPHV--ETIEEDRERVEELEAELEDLEEEVEEVEERLERA 501

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1891 TKLKETA------EEEKDDLEERLMNQLAELNgsignyyQDVTDAQIKNEQ---LESEMRNLQRCVSELEEEKQQlVKEK 1961
Cdd:PRK02224   502 EDLVEAEdrierlEERREDLEELIAERRETIE-------EKRERAEELRERaaeLEAEAEEKREAAAEAEEEAEE-AREE 573

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1962 TKVESEIRKEYMEKIQGAQKGPANKSHAKELQELLREKQQEVKQLQKDCIRYLERISALEKTVKALEFVHTESqkdldvt 2041
Cdd:PRK02224   574 VAELNSKLAELKERIESLERIRTLLAAIADAEDEIERLREKREALAELNDERRERLAEKRERKRELEAEFDEA------- 646

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2042 kgNLAQAVEHRKKAQAELSSFKILLDDTQSEaarvladnlklKKELQSNKESIKSQIKQKdEDLLRRLEQAEEKHrkekk 2121
Cdd:PRK02224   647 --RIEEAREDKERAEEYLEQVEEKLDELREE-----------RDDLQAEIGAVENELEEL-EELRERREALENRV----- 707

                          570       580
                   ....*....|....*....|....*..
gi 1720386946 2122 nmqEKLDALHREKAHVEETLAEIQVSL 2148
Cdd:PRK02224   708 ---EALEALYDEAEELESMYGDLRAEL 731
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 2680-3034 8.61e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 48.53  E-value: 8.61e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2680 VAELARDLVEMEQKLLTVTKENKDLMAQIQAFGRSMSSLQDSRDHATEELGDLKKKYDASLKELaqLKEWQDSSREgdvl 2759
Cdd:TIGR02169  165 VAEFDRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAERYQALLKEKREYEGYEL--LKEKEALERQ---- 238

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2760 sqaafpLSTSENVLSRLEKLNQQLTSKDEQLLHLSSELESSHNQVQSISKAMTSlqNERDRLWSELEKFrkseEGKQRAA 2839
Cdd:TIGR02169  239 ------KEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGE--EEQLRVKEKIGEL----EAEIASL 306

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2840 APSAASSPAEVQSLKKAMSSLQNDRDRLLKELKNL----QQQYLQMSQEMTELRPLKAQLQESQDQTKALQVMEEELRQE 2915
Cdd:TIGR02169  307 ERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELereiEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDE 386

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2916 NLSWQHELRQLRMEKNSWELHERRM---KEQFLMAISDKDQQLGHLQSLLRELRSSSQAQILSTQYQRQASPETSASLDG 2992
Cdd:TIGR02169  387 LKDYREKLEKLKREINELKRELDRLqeeLQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSK 466

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|..
gi 1720386946 2993 SQKLVYEtelLRTQLNDSLKEIHQKELRIQQLNSKFSQLLEE 3034
Cdd:TIGR02169  467 YEQELYD---LKEEYDRVEKELSKLQRELAEAEAQARASEER 505
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
678-1037 9.72e-05

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 48.11  E-value: 9.72e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  678 QGELERLKTQVLELETSLHTAEETYKRNLsekvKEISSLTQLSEEVKESAEEARSTLAAVTEERDQLLYQVKELDV-LAE 756
Cdd:PRK02224   320 EDRDEELRDRLEECRVAAQAHNEEAESLR----EDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEeIEE 395

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  757 LRARVQELESSLAEAEKQRgldyESQRAQHNLLTEQIHSLSIEAKSKDVKIEALQRELDGVQLQFCEQGTQMKTLQSQLE 836
Cdd:PRK02224   396 LRERFGDAPVDLGNAEDFL----EELREERDELREREAELEATLRTARERVEEAEALLEAGKCPECGQPVEGSPHVETIE 471

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  837 AKEREVREGTERLRDISQEMEGLSQALSQKE--LEIAKMDQLLLEKQKDVETL-----------QQTIQEKDQQVTELSF 903
Cdd:PRK02224   472 EDRERVEELEAELEDLEEEVEEVEERLERAEdlVEAEDRIERLEERREDLEELiaerretieekRERAEELRERAAELEA 551

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  904 SMTEKMVQ---LNEEKFSLGVEIKTLKEQLNLLSRTEEATkEQVEESGAGSSLKLGHDESGQEGLQQ--ELELLRKE--S 976
Cdd:PRK02224   552 EAEEKREAaaeAEEEAEEAREEVAELNSKLAELKERIESL-ERIRTLLAAIADAEDEIERLREKREAlaELNDERRErlA 630

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1720386946  977 EQRKRK--------------LQAALINRKELLQKVSQLEEELAKVREDSRKEIPFGENERRKLEEDRENRDDPEE 1037
Cdd:PRK02224   631 EKRERKreleaefdearieeAREDKERAEEYLEQVEEKLDELREERDDLQAEIGAVENELEELEELRERREALEN 705
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 153-928 1.02e-04

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 48.14  E-value: 1.02e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  153 HELQEKEKLISSLQAQLDQSEQasQLDKSSAEMEDFVlmkQQLQEKEELISTLQTQLSQTQAEQAAQVVRE------KDA 226
Cdd:TIGR02169  230 KEKEALERQKEAIERQLASLEE--ELEKLTEEISELE---KRLEEIEQLLEELNKKIKDLGEEEQLRVKEKigeleaEIA 304

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  227 RFETQVRLHEDELLQLVTQsdvETEMQQKLRVMQRKLEEHEEALLGRAQVVDLLQKELTSAEQRNQVLSQQLQLLEAEHN 306
Cdd:TIGR02169  305 SLERSIAEKERELEDAEER---LAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFA 381

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  307 TLKNTMETERQE-SKTLMEKVELEVAERKL--SFHNLQEEMHQLQGQLERAGQAQADLEtqysalqqrhktemEEKTACI 383
Cdd:TIGR02169  382 ETRDELKDYREKlEKLKREINELKRELDRLqeELQRLSEELADLNAAIAGIEAKINELE--------------EEKEDKA 447

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  384 LSLQKNEQELQSACAALKEENSKLLQEKHDQaaesaqamRQLEDQLQQKSKEISQFVNKPNLQKNETASQTSLPDVNNEG 463
Cdd:TIGR02169  448 LEIKKQEWKLEQLAADLSKYEQELYDLKEEY--------DRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKAS 519

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  464 DQAVMeETVASLQKrvVELENEKGALLLSSGELEELKAENEKLSSRITLLEAQNRAGEAdgtvcevstagTTLLNRSDSS 543
Cdd:TIGR02169  520 IQGVH-GTVAQLGS--VGERYATAIEVAAGNRLNNVVVEDDAVAKEAIELLKRRKAGRA-----------TFLPLNKMRD 585

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  544 PEENGQAVLENTFSqkhkELSVLLVEMKEAQEEIAF-------LKSQLQGKRPEGDYEVLDRREVQLMESEGppSVTAGD 616
Cdd:TIGR02169  586 ERRDLSILSEDGVI----GFAVDLVEFDPKYEPAFKyvfgdtlVVEDIEAARRLMGKYRMVTLEGELFEKSG--AMTGGS 659

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  617 VlcAPSDESSGPAAEEEQAgmkdrhraseagplndagmELSSPKLDGVDKSLAVShvcqchQGELERLKTQVLELETSLH 696
Cdd:TIGR02169  660 R--APRGGILFSRSEPAEL-------------------QRLRERLEGLKRELSSL------QSELRRIENRLDELSQELS 712

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  697 TAEetykRNLSEKVKEISSLTQLSEEVKESAEEARSTLAAVTEERDQLLYQVKELD--------VLAELRARVQELESSL 768
Cdd:TIGR02169  713 DAS----RKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEarieeleeDLHKLEEALNDLEARL 788

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  769 AEAE-KQRGLDYESQRAQHNLLTEQIHSLSIEAKSKDVKIEALQRELDGVQLQFCEQGTQMKTLQSQLEAKEREVREGTE 847
Cdd:TIGR02169  789 SHSRiPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEE 868

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  848 RLRDISQEMEGLSQALSQKELEIAKMDQLLLEKQKDVETLQQTIQEKDQQVTELsfsmTEKMVQLNEEKFSLGVEIKTLK 927
Cdd:TIGR02169  869 ELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSEL----KAKLEALEEELSEIEDPKGEDE 944


                   .
gi 1720386946  928 E 928
Cdd:TIGR02169  945 E 945
46 PHA02562
endonuclease subunit; Provisional
 2519-2748 1.20e-04

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 47.70  E-value: 1.20e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2519 RRDLNE------VIAIKDSQQKQLLDAQLQQNKELRNECTKLEERLKGLEAEKQSLQMSSDALQKEKQG----LSKEIKN 2588
Cdd:PHA02562   152 RRKLVEdlldisVLSEMDKLNKDKIRELNQQIQTLDMKIDHIQQQIKTYNKNIEEQRKKNGENIARKQNkydeLVEEAKT 231

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2589 LQTQLTALQEEgtLGVYHAQLKAKEEELQRLNMALS--SSQKRTADLEEEL--------VCVQK---------EATRKVS 2649
Cdd:PHA02562   232 IKAEIEELTDE--LLNLVMDIEDPSAALNKLNTAAAkiKSKIEQFQKVIKMyekggvcpTCTQQisegpdritKIKDKLK 309

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2650 EIEDQLKKELKHLHHDAGIMrNETETAEERVAELARDLVEMEQKLLTVTKENKDLMAQIQafgrsmsSLQDSRDHATEEL 2729
Cdd:PHA02562   310 ELQHSLEKLDTAIDELEEIM-DEFNEQSKKLLELKNKISTNKQSLITLVDKAKKVKAAIE-------ELQAEFVDNAEEL 381

                          250
                   ....*....|....*....
gi 1720386946 2730 GDLKKKYDASLKELAQLKE 2748
Cdd:PHA02562   382 AKLQDELDKIVKTKSELVK 400
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 1835-2689 1.32e-04

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 47.86  E-value: 1.32e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1835 EMEKQKDRELSQALENEKNAlltqisakDSELKLLEEEVTKRTTLNQQIQEELCRVTKLKETAEEekddLEERLMNQLAE 1914
Cdd:pfam01576    5 EEMQAKEEELQKVKERQQKA--------ESELKELEKKHQQLCEEKNALQEQLQAETELCAEAEE----MRARLAARKQE 72

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1915 LNGSIGNYYQDVTDAQIKNEQLESEMRNLQRCVSELEEE-------KQQLVKEKTKVESEIRKEYMEKIQGAQKGPANKS 1987
Cdd:pfam01576   73 LEEILHELESRLEEEEERSQQLQNEKKKMQQHIQDLEEQldeeeaaRQKLQLEKVTTEAKIKKLEEDILLLEDQNSKLSK 152

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1988 HAKELQEL-------LREKQQEVKQLQKDCIRYLERISALEKTVKALEFVHTESQKDLDVTKGNLAQAVEHRKKAQAELS 2060
Cdd:pfam01576  153 ERKLLEERiseftsnLAEEEEKAKSLSKLKNKHEAMISDLEERLKKEEKGRQELEKAKRKLEGESTDLQEQIAELQAQIA 232

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2061 SFKILLDDTQSEAARVLA---DNLKLKKELQSNKESIKSQIKQKDEDLLRRlEQAEEKHRKEKKNMQEKLDALHREKAHV 2137
Cdd:pfam01576  233 ELRAQLAKKEEELQAALArleEETAQKNNALKKIRELEAQISELQEDLESE-RAARNKAEKQRRDLGEELEALKTELEDT 311

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2138 EETLAEIQVSLTRKDQEMKELQGSLDSTL----AQLAAFTKSMSSLQDDRDRVIDEAKKWERRFGDAIQTKEE------- 2206
Cdd:pfam01576  312 LDTTAAQQELRSKREQEVTELKKALEEETrsheAQLQEMRQKHTQALEELTEQLEQAKRNKANLEKAKQALESenaelqa 391

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2207 EVRLKEENCIALKDQLRQMAIHMEELKITVSRLEHDKEIWE---SKAQTELQHHQKAYD-------KLQEENKELTSQLE 2276
Cdd:pfam01576  392 ELRTLQQAKQDSEHKRKKLEGQLQELQARLSESERQRAELAeklSKLQSELESVSSLLNeaegkniKLSKDVSSLESQLQ 471

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2277 DARQLYHDSKNELTKLESELKSLKDQTTDLNNSLEKCKEHENNLEGIIKQQEADIQNCKFSCEQLETDLAASRELTSRLH 2356
Cdd:pfam01576  472 DTQELLQEETRQKLNLSTRLRQLEDERNSLQEQLEEEEEAKRNVERQLSTLQAQLSDMKKKLEEDAGTLEALEEGKKRLQ 551

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2357 DEINAKEQkiisllsgKEEAIQLAVEELHQQHSKEIKELENLLSQEEEENVALEEENKR--------ALEKT--NQLTEA 2426
Cdd:pfam01576  552 RELEALTQ--------QLEEKAAAYDKLEKTKNRLQQELDDLLVDLDHQRQLVSNLEKKqkkfdqmlAEEKAisARYAEE 623

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2427 LEAIKKESFEQKAQLDSFVKSMSSLQDDRDRIVSDYRQLEERHLSAILEKDQL---IQDAAAENNKLKEEMRGLRSHMDD 2503
Cdd:pfam01576  624 RDRAEAEAREKETRALSLARALEEALEAKEELERTNKQLRAEMEDLVSSKDDVgknVHELERSKRALEQQVEEMKTQLEE 703

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2504 LN-----SENAKLDAEL------VQYRRDLNEVIAIKDSQQKQLLDAQLQQNKELRNECTKLEERL---KGLEAEKQSLQ 2569
Cdd:pfam01576  704 LEdelqaTEDAKLRLEVnmqalkAQFERDLQARDEQGEEKRRQLVKQVRELEAELEDERKQRAQAVaakKKLELDLKELE 783

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2570 MSSDALQKEKQGLSKEIKNLQTQLTALQEEgtlgvyhaqlkAKEEELQRLNMALSS--SQKRTADLEEELVCVQKE---- 2643
Cdd:pfam01576  784 AQIDAANKGREEAVKQLKKLQAQMKDLQRE-----------LEEARASRDEILAQSkeSEKKLKNLEAELLQLQEDlaas 852

                          890       900       910       920
                   ....*....|....*....|....*....|....*....|....*...
gi 1720386946 2644 --ATRKVSEIEDQLKKELKHLHHDAGIMRNETETAEERVAELARDLVE 2689
Cdd:pfam01576  853 erARRQAQQERDELADEIASGASGKSALQDEKRRLEARIAQLEEELEE 900
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 1150-1969 1.32e-04

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 48.12  E-value: 1.32e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1150 LEGRILDLEKDKTQLQKKLQEALIARKAILKKAQE-KEKQLKEELREQKDAYHHLQGQFHEQ---NKEKENIADQLRQLQ 1225
Cdd:TIGR00606  274 LKSRKKQMEKDNSELELKMEKVFQGTDEQLNDLYHnHQRTVREKERELVDCQRELEKLNKERrllNQEKTELLVEQGRLQ 353

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1226 CQARESIDRQLPGTGQQEPGPPAPSLEGISlEDTEPASESDLHAAQPSPPGETAALQATVSVAQIQAQLKEMEVEKEELE 1305
Cdd:TIGR00606  354 LQADRHQEHIRARDSLIQSLATRLELDGFE-RGPFSERQIKNFHTLVIERQEDEAKTAAQLCADLQSKERLKQEQADEIR 432

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1306 LKVSSIASELAKKSEEVLLLQDQINEQGLEIQNLKAASVEA-QAHTELLKQELESSQL--------KVAGLEHLKTLQPE 1376
Cdd:TIGR00606  433 DEKKGLGRTIELKKEILEKKQEELKFVIKELQQLEGSSDRIlELDQELRKAERELSKAeknsltetLKKEVKSLQNEKAD 512

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1377 LDALHKHMGQKEEEVNYLYGQLSEKEqTLTTVQTEMVEQERLIKALHTQLEMQAKEHEERLKQAQVEICELKKKPTELEE 1456
Cdd:TIGR00606  513 LDRKLRKLDQEMEQLNHHTTTRTQME-MLTKDKMDKDEQIRKIKSRHSDELTSLLGYFPNKKQLEDWLHSKSKEINQTRD 591

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1457 ETnakQQLQRKLQAALISRKEALKENKSLQEQLSSARDAVERLTKSlADVESQVSVQNQEKDAVLGKLTILQEERDKLIA 1536
Cdd:TIGR00606  592 RL---AKLNKELASLEQNKNHINNELESKEEQLSSYEDKLFDVCGS-QDEESDLERLKEEIEKSSKQRAMLAGATAVYSQ 667

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1537 EMDRFLLENQSLSGSCESLKLALGGLTEdkekLMEELESVRSSKMAESTEWQEKHKELQKEYEVLLQSYENVSNEAERIQ 1616
Cdd:TIGR00606  668 FITQLTDENQSCCPVCQRVFQTEAELQE----FISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKE 743

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1617 HVVESVRQEKQELYAKLRSTESDKREREKQLQ--DAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEAQPVGGTgE 1694
Cdd:TIGR00606  744 KEIPELRNKLQKVNRDIQRLKNDIEEQETLLGtiMPEEESAKVCLTDVTIMERFQMELKDVERKIAQQAAKLQGSDLD-R 822

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1695 SMEALLSSNSSLKEELEKITLEHKTLSKEFEALMAEKDALSEETRNLKlqVEAQVLKQASLEATEKSDEPKDVIEEVTQA 1774
Cdd:TIGR00606  823 TVQQVNQEKQEKQHELDTVVSKIELNRKLIQDQQEQIQHLKSKTNELK--SEKLQIGTNLQRRQQFEEQLVELSTEVQSL 900

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1775 VVGKSQERDALSDSAKLEDSEAILMGDGAKPGVSETFSSHDDIKNYLQQLDQLKGRIAELEMEKQ--KDRELSQAlENEK 1852
Cdd:TIGR00606  901 IREIKDAKEQDSPLETFLEKDQQEKEELISSKETSNKKAQDKVNDIKEKVKNIHGYMKDIENKIQdgKDDYLKQK-ETEL 979

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1853 NALLTQISAKDSELKLLEEEV--TKRTTLNQQIQEELCRVTKLKETAEEEKDDLEERLMNQLAELNgsignyYQDVTDAQ 1930
Cdd:TIGR00606  980 NTVNAQLEECEKHQEKINEDMrlMRQDIDTQKIQERWLQDNLTLRKRENELKEVEEELKQHLKEMG------QMQVLQMK 1053

                          810       820       830
                   ....*....|....*....|....*....|....*....
gi 1720386946 1931 IKNEQLESEMRNLQRCVSELEEEKQQLVKEKTKVESEIR 1969
Cdd:TIGR00606 1054 QEHQKLEENIDLIKRNHVLALGRQKGYEKEIKHFKKELR 1092
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 1583-2157 1.42e-04

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 47.66  E-value: 1.42e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1583 ESTEWQEKHKELQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQELYAKLRSTESDKREREKQLQDAEQEMEEMKEKMR 1662
Cdd:TIGR00618  270 EELRAQEAVLEETQERINRARKAAPLAAHIKAVTQIEQQAQRIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQT 349

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1663 KFAKSKQQKI-----LELEEENDRLRAEAQPVGGTGESMEALLSSNSSLKEELEKITLEHKTLSKEFEALMAEKDALSEE 1737
Cdd:TIGR00618  350 LHSQEIHIRDahevaTSIREISCQQHTLTQHIHTLQQQKTTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAHA 429

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1738 TRNLKLQVEAQVLKQASLEATEKSDEPKDV--------IEEVTQAVVGKSQERDALSDSAKLEDSEAILMGDGAKPGVSE 1809
Cdd:TIGR00618  430 KKQQELQQRYAELCAAAITCTAQCEKLEKIhlqesaqsLKEREQQLQTKEQIHLQETRKKAVVLARLLELQEEPCPLCGS 509

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1810 TFSSHDDIKNYLQ------QLDQLKGRIAELEMEKQKDRELSQALENEKNALLTQISAKDSELKLLEEEVTKRTTLNQQI 1883
Cdd:TIGR00618  510 CIHPNPARQDIDNpgpltrRMQRGEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNL 589

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1884 QEELCRVTKLKETAEEEKDDLEERLMNQLAELNGSIGNYYQDVTDAQIKNEQLESEM---RNLQRCVSELEEEKQQLVKE 1960
Cdd:TIGR00618  590 QNITVRLQDLTEKLSEAEDMLACEQHALLRKLQPEQDLQDVRLHLQQCSQELALKLTalhALQLTLTQERVREHALSIRV 669

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1961 KTKVESEIRKEYMEKIQG-AQKGPANKSHAKELQELLREKQQEVKQLQKDCIRYLERISALEKTVKALEFVHTESQKDLD 2039
Cdd:TIGR00618  670 LPKELLASRQLALQKMQSeKEQLTYWKEMLAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKELM 749

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2040 VTKGNLAQAVEHRKKAQAELSSFKILLDDTQSEAARVLADNLKLKKELQSNKESIKSQIKQKDEDLLRRLEQAEEKHRKE 2119
Cdd:TIGR00618  750 HQARTVLKARTEAHFNNNEEVTAALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQCETLVQE 829

                          570       580       590
                   ....*....|....*....|....*....|....*...
gi 1720386946 2120 KKNMQEKLDALHREKAHVEETLAEIQVSLTRKDQEMKE 2157
Cdd:TIGR00618  830 EEQFLSRLEEKSATLGEITHQLLKYEECSKQLAQLTQE 867
PRK11281 PRK11281
mechanosensitive channel MscK;
2262-2625 1.74e-04

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 47.60  E-value: 1.74e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2262 DKLQEENKELTSQLEDARQLYHDSKNELTKLESELKSLKDQTTDlNNSLEKckehennLEGIIKQQEADIQNCKFSCEQL 2341
Cdd:PRK11281    76 DRQKEETEQLKQQLAQAPAKLRQAQAELEALKDDNDEETRETLS-TLSLRQ-------LESRLAQTLDQLQNAQNDLAEY 147

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2342 ETDLAASRELTSRLHDEINA---KEQKIISLLSGKEEAIQLAVEELHQQHSKEIKELENLLSQeeeenvaleeeNKRALE 2418
Cdd:PRK11281   148 NSQLVSLQTQPERAQAALYAnsqRLQQIRNLLKGGKVGGKALRPSQRVLLQAEQALLNAQNDL-----------QRKSLE 216

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2419 KTNQLTEALEAIKKESFEQKAQLDSFVKSMSSLQDDRDRIVSD--YRQLEERHLSAILEKDQLIQDAAAENNKLKEEMRG 2496
Cdd:PRK11281   217 GNTQLQDLLQKQRDYLTARIQRLEHQLQLLQEAINSKRLTLSEktVQEAQSQDEAARIQANPLVAQELEINLQLSQRLLK 296

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2497 LRSHMDDLNSENAK----LDaELVQYRRDLNEVI-AIKDS--------QQKQLLdAQLQQNKELRNECTKLeeRLKGLEA 2563
Cdd:PRK11281   297 ATEKLNTLTQQNLRvknwLD-RLTQSERNIKEQIsVLKGSlllsrilyQQQQAL-PSADLIEGLADRIADL--RLEQFEI 372

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1720386946 2564 EKQSLQMSSDA------LQKEKQGLSKEIKNlqtQLTALqeegtlgvyhaqLKAKEEELQRLNMALSS 2625
Cdd:PRK11281   373 NQQRDALFQPDayidklEAGHKSEVTDEVRD---ALLQL------------LDERRELLDQLNKQLNN 425
PRK11281 PRK11281
mechanosensitive channel MscK;
1371-1548 1.86e-04

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 47.60  E-value: 1.86e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1371 KTLQPELDALHKHmGQKEEEVNYLYGQLsekEQTLTTV-QTEMVEQErlikalHTQLEMQAKEHEERLKQAQVEICELKK 1449
Cdd:PRK11281    39 ADVQAQLDALNKQ-KLLEAEDKLVQQDL---EQTLALLdKIDRQKEE------TEQLKQQLAQAPAKLRQAQAELEALKD 108

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1450 KPTELEEETNAKQ---QLQRKLQAALISRKEALKENKSLQEQLSSARDAVERLTKSLAdvESQVSVQ---NQEKDAVLGK 1523
Cdd:PRK11281   109 DNDEETRETLSTLslrQLESRLAQTLDQLQNAQNDLAEYNSQLVSLQTQPERAQAALY--ANSQRLQqirNLLKGGKVGG 186

                          170       180       190
                   ....*....|....*....|....*....|....
gi 1720386946 1524 LTILQEERDKLIAEMD---------RFLLENQSL 1548
Cdd:PRK11281   187 KALRPSQRVLLQAEQAllnaqndlqRKSLEGNTQ 220
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
719-1110 1.88e-04

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 47.34  E-value: 1.88e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  719 LSEEVKESAEEARSTLAAVTEERDQLLYQVKELDVLAELRARVQELESSLAEAEKQRGLDYESQRAQHNLLTEQIHSLSI 798
Cdd:PRK02224   277 LAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLEE 356

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  799 EAKSKDVKIEALQRELDGVQLQFCEQGTQMKTLQSQLEAKEREVREGTERLRDISQEMEGLSQALSQKELEIAKMDQLLL 878
Cdd:PRK02224   357 RAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAELEATLR 436

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  879 EKQKDVETLQQ---------------------TIQEKDQQVTELSFSMTEKMVQLN--EEKFSLGVEIKTLKEQLNLLSR 935
Cdd:PRK02224   437 TARERVEEAEAlleagkcpecgqpvegsphveTIEEDRERVEELEAELEDLEEEVEevEERLERAEDLVEAEDRIERLEE 516

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  936 TEEATKEQVEESGAGsslkLGHDESGQEGLQQELELLRKESEQRKRKLQAALINRKELLQKVSQLEEELAKVRE------ 1009
Cdd:PRK02224   517 RREDLEELIAERRET----IEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKEriesle 592

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1010 DSRKEIPFGENERRKLEEDRENRDDPEEWGTSKwREVEASLKQTISEKEVELEGirrdlkektAAEEELQAVVQRMTRDL 1089
Cdd:PRK02224   593 RIRTLLAAIADAEDEIERLREKREALAELNDER-RERLAEKRERKRELEAEFDE---------ARIEEAREDKERAEEYL 662

                          410       420
                   ....*....|....*....|.
gi 1720386946 1090 QSKTKQIDLLQEEVTENQATI 1110
Cdd:PRK02224   663 EQVEEKLDELREERDDLQAEI 683
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 1353-1637 1.88e-04

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 47.23  E-value: 1.88e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1353 LKQELES--SQLKVAGLEHLKTLQPELDA-----LHKHMGQKEEEVNYLyGQLSEKEQTLTTVQTEMVEQErlikalhtq 1425
Cdd:PRK05771    14 LKSYKDEvlEALHELGVVHIEDLKEELSNerlrkLRSLLTKLSEALDKL-RSYLPKLNPLREEKKKVSVKS--------- 83

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1426 LEMQAKEHEERLKQAQVEICELKKKPTELEEEtnaKQQLQRKLQAALISRK-----EALKENKSLQEQLSSARDAVERLT 1500
Cdd:PRK05771    84 LEELIKDVEEELEKIEKEIKELEEEISELENE---IKELEQEIERLEPWGNfdldlSLLLGFKYVSVFVGTVPEDKLEEL 160

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1501 KSLADVESQVSV-QNQEKDAVLgkLTILQEERDKLIAEMDRFLLENQSLSGScESLKLALGGLTEDKEKLMEELESVRss 1579
Cdd:PRK05771   161 KLESDVENVEYIsTDKGYVYVV--VVVLKELSDEVEEELKKLGFERLELEEE-GTPSELIREIKEELEEIEKERESLL-- 235

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1720386946 1580 kmaestewqEKHKELQKEYE-VLLQSYENVSNEAERiqhvvesvrqekQELYAKLRSTE 1637
Cdd:PRK05771   236 ---------EELKELAKKYLeELLALYEYLEIELER------------AEALSKFLKTD 273
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2509-2739 1.91e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 46.68  E-value: 1.91e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2509 AKLDAELVQYRRDLNEVIAikdsQQKQLLDAQLQQNKELRNECTKLEERLKGLEAEKQSLQMSSDALQKEKQGLSKEIKN 2588
Cdd:COG4942     19 ADAAAEAEAELEQLQQEIA----ELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAE 94

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2589 LQTQLTALQEEGTLGVYHAQLKAKEEELQRLNMALSSSQK-RTADLEEELVCVQKEATRKVSEIEDQLKKELKHLHHDAG 2667
Cdd:COG4942     95 LRAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAvRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERA 174

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1720386946 2668 IMRNETETAEERVAELARDLVEMEQKLLTVTKENKDLMAQIQAFGRSMSSLQDSRDHATEELGDLKKKYDAS 2739
Cdd:COG4942    175 ELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAA 246
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2533-2752 2.01e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 46.68  E-value: 2.01e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2533 QKQLLDAQLQQNKELRNECTKLEERLKGLEAEKQSLQMSSDALQKEKQGLSKEIKNLQTQLTALQEEgtlgvyHAQLKAK 2612
Cdd:COG4942     18 QADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAE------LAELEKE 91

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2613 EEELQRlnmalsSSQKRTADLEEELVCVQKeaTRKVSEIEDQLK-KELKHLHHDAGIMRNETETAEERVAELARDLVEME 2691
Cdd:COG4942     92 IAELRA------ELEAQKEELAELLRALYR--LGRQPPLALLLSpEDFLDAVRRLQYLKYLAPARREQAEELRADLAELA 163

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1720386946 2692 QKLLTVTKENKDLMAQIQAFGRSMSSLQDSRDHATEELGDLKKKYDASLKELAQLKEWQDS 2752
Cdd:COG4942    164 ALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEE 224
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1301-1745 2.15e-04

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 46.94  E-value: 2.15e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1301 KEELELKVSSIASELAKKSEEVLLLQDQINEQGLEIQNLKAASVEAQAHTELLKQELESSQLKVAGLE-HLKTLQPELDA 1379
Cdd:TIGR04523  220 ISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEkQLNQLKSEISD 299

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1380 LHKhmgQKEEEVN-YLYGQLSEKEQTLTTVQTEMVEQERLIKALHTQLEMQAKEHEERLKQAQVEICELKKKPTELEEET 1458
Cdd:TIGR04523  300 LNN---QKEQDWNkELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLK 376

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1459 NAKQQLQRKLQaALISRKEAL--------KENKSLQEQLSSARDAVERLTKSLADVESQVSVQNQEKDAVLGKLTILQEE 1530
Cdd:TIGR04523  377 KENQSYKQEIK-NLESQINDLeskiqnqeKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELI 455

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1531 RDKLIAEMDRFLLENQSLSGSCESLKLALggltEDKEKLMEELESVRSSKMAESTEWQEKHKELQKEYEVLLQSYENVSN 1610
Cdd:TIGR04523  456 IKNLDNTRESLETQLKVLSRSINKIKQNL----EQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLES 531

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1611 EAERIQHVVESVRQEKQELYAKLRSTESDKREREKQLQDAEQEMEEMKEKMRKfaKSKQQKILELEEENDRLRAEaqpvg 1690
Cdd:TIGR04523  532 EKKEKESKISDLEDELNKDDFELKKENLEKEIDEKNKEIEELKQTQKSLKKKQ--EEKQELIDQKEKEKKDLIKE----- 604

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1720386946 1691 gtgesMEALLSSNSSLKEELEKITLEHKTLSKEFEALMAEKDALSEETRNLKLQV 1745
Cdd:TIGR04523  605 -----IEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETI 654
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
806-1021 2.17e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 47.22  E-value: 2.17e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  806 KIEALQRELDGVQLQFCEQGTQMKTLQSQLEA--KEREVREGTERLRDISQEMEGLSQALSQKELEIAKmdqlLLEKQKD 883
Cdd:COG4913    611 KLAALEAELAELEEELAEAEERLEALEAELDAlqERREALQRLAEYSWDEIDVASAEREIAELEAELER----LDASSDD 686

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  884 VETLQQTIQEKDQQVTElsfsmtekmvqLNEEKFSLGVEIKTLKEQLNLLSRTEEATKEQVEESGAGsslklghdesGQE 963
Cdd:COG4913    687 LAALEEQLEELEAELEE-----------LEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDL----------ARL 745

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1720386946  964 GLQQELELLRKESEQRK--RKLQAALINRKELLQ-KVSQLEEELAKVREDSRKEIPFGENE 1021
Cdd:COG4913    746 ELRALLEERFAAALGDAveRELRENLEERIDALRaRLNRAEEELERAMRAFNREWPAETAD 806
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 801-1082 2.23e-04

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 46.84  E-value: 2.23e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  801 KSKDVKIEALQrELDGVQLQFCEQGTQMKTLqSQLEAKEREVREGTERLRDISQEmEGLSQALsQKELEIAKMDQLLLEK 880
Cdd:PRK05771    16 SYKDEVLEALH-ELGVVHIEDLKEELSNERL-RKLRSLLTKLSEALDKLRSYLPK-LNPLREE-KKKVSVKSLEELIKDV 91

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  881 QKDVETLQQTIQEKDQQVTELsfsmTEKMVQLNEEKF------SLGVEIKTLKEQLNLLSRTEEATKEQVEESGAgsslk 954
Cdd:PRK05771    92 EEELEKIEKEIKELEEEISEL----ENEIKELEQEIErlepwgNFDLDLSLLLGFKYVSVFVGTVPEDKLEELKL----- 162

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  955 lghdESGQEGLqqelellrKESEQRKRKLQAALINRKELLQKVsqlEEELAKVrEDSRKEIPfgenerrkleedrenrdd 1034
Cdd:PRK05771   163 ----ESDVENV--------EYISTDKGYVYVVVVVLKELSDEV---EEELKKL-GFERLELE------------------ 208

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*...
gi 1720386946 1035 peEWGTSKwrEVEASLKQTISEKEVELEGIRRDLKEKTAAEEELQAVV 1082
Cdd:PRK05771   209 --EEGTPS--ELIREIKEELEEIEKERESLLEELKELAKKYLEELLAL 252
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
681-863 2.31e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 47.22  E-value: 2.31e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  681 LERLKTQVLELETSLHTAEETYK------RNLSEKVKEISSLTQLSEEVKESAEeARSTLAAVTEERDQLLyqvKELDVL 754
Cdd:COG4913    612 LAALEAELAELEEELAEAEERLEaleaelDALQERREALQRLAEYSWDEIDVAS-AEREIAELEAELERLD---ASSDDL 687

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  755 AELRARVQELESSLAEAEKQRgldyESQRAQHNLLTEQIHSLSIEAKSKDVKIEALQRELDGVQLQFCEQgtqmKTLQSQ 834
Cdd:COG4913    688 AALEEQLEELEAELEELEEEL----DELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEE----RFAAAL 759

                          170       180       190
                   ....*....|....*....|....*....|
gi 1720386946  835 LEAKEREVREG-TERLRDISQEMEGLSQAL 863
Cdd:COG4913    760 GDAVERELRENlEERIDALRARLNRAEEEL 789
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1279-1504 2.48e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 46.30  E-value: 2.48e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1279 AALQATVSVAQIQAQLKEMEVEKEELELKVSSIASELAKKSEEVLLLQDQINEQGLEIQNLKAASVEAQAHTELLKQELE 1358
Cdd:COG4942     14 AAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIA 93

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1359 SSQLKVAGLEHLktLQPELDALHKHMGQKEEEV---NYLYGQLSEKEQTLTTVQTEMVEQERLIKALHTQLEMQAKEHEE 1435
Cdd:COG4942     94 ELRAELEAQKEE--LAELLRALYRLGRQPPLALllsPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEA 171

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1720386946 1436 RLKQAQVEICELKKKPTELEEETNAKQQLQRKLQAALISRKEALKENKSLQEQLSSARDAVERLTKSLA 1504
Cdd:COG4942    172 ERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAA 240
PRK01156 PRK01156
chromosome segregation protein; Provisional
 1485-2037 2.64e-04

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 46.82  E-value: 2.64e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1485 LQEQLSSARDAVERLTKSLADVESQVSVQNQEKDAVLGKLTILQEERDKLIAEMDRFLLENQSLSGSCESLKLALGGLTE 1564
Cdd:PRK01156   188 LEEKLKSSNLELENIKKQIADDEKSHSITLKEIERLSIEYNNAMDDYNNLKSALNELSSLEDMKNRYESEIKTAESDLSM 267

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1565 DKEK------LMEELESVRSSKMAESTEWQEKHKELQKEYEVLLQSYENVSNEAERIQHVVESVrQEKQELYAKLRSTES 1638
Cdd:PRK01156   268 ELEKnnyykeLEERHMKIINDPVYKNRNYINDYFKYKNDIENKKQILSNIDAEINKYHAIIKKL-SVLQKDYNDYIKKKS 346

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1639 DKREREKQLQDAEQEMEEMKEKMRKFaKSKQQKILELEEENDRLRAEAQPVGGTGE-SMEALLSSNSSLKEELEKITLEH 1717
Cdd:PRK01156   347 RYDDLNNQILELEGYEMDYNSYLKSI-ESLKKKIEEYSKNIERMSAFISEILKIQEiDPDAIKKELNEINVKLQDISSKV 425

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1718 KTLSKEFEALMAEKDALSEETRNLKLQVEAQVLkqASLEATEKSdepKDVIEEVTQAVVGKSQERDALSDSAKLEDSEAI 1797
Cdd:PRK01156   426 SSLNQRIRALRENLDELSRNMEMLNGQSVCPVC--GTTLGEEKS---NHIINHYNEKKSRLEEKIREIEIEVKDIDEKIV 500

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1798 LMGDgakpgvSETFSSHDDIKNYLQQLDQLKGRIAELEMEKQKDRELSQAlENEKNALLTQISAKDseLKLLEEEVTKRT 1877
Cdd:PRK01156   501 DLKK------RKEYLESEEINKSINEYNKIESARADLEDIKIKINELKDK-HDKYEEIKNRYKSLK--LEDLDSKRTSWL 571

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1878 TLNQQIQE-ELCRVTKLKETAEEEKDDLEERLM--------------NQLAELNGSIGNY---YQDVTDAQIKNEQLESE 1939
Cdd:PRK01156   572 NALAVISLiDIETNRSRSNEIKKQLNDLESRLQeieigfpddksyidKSIREIENEANNLnnkYNEIQENKILIEKLRGK 651

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1940 MRNLQRCVSELEEEKQQLvKEKTKVESEIRKEYMEKIQGAQKGPANKSHAKELQELLREKQQEVKQLQKDCIRYLERISA 2019
Cdd:PRK01156   652 IDNYKKQIAEIDSIIPDL-KEITSRINDIEDNLKKSRKALDDAKANRARLESTIEILRTRINELSDRINDINETLESMKK 730

                          570
                   ....*....|....*...
gi 1720386946 2020 LEKTVKALEFVHTESQKD 2037
Cdd:PRK01156   731 IKKAIGDLKRLREAFDKS 748
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 1414-1686 2.73e-04

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 46.84  E-value: 2.73e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1414 EQERLIKALHtqlEMQAkeheerlkqaqVEICELKKKptELEEETNAKQQLQRKLQAALISRKEALKENKSLQEQLSSAR 1493
Cdd:PRK05771    17 YKDEVLEALH---ELGV-----------VHIEDLKEE--LSNERLRKLRSLLTKLSEALDKLRSYLPKLNPLREEKKKVS 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1494 -----DAVERLTKSLADVESQVSVQNQEkdavlgkLTILQEERDKLIAEMDR------FLLENQSLSGScESLKLALGGL 1562
Cdd:PRK05771    81 vksleELIKDVEEELEKIEKEIKELEEE-------ISELENEIKELEQEIERlepwgnFDLDLSLLLGF-KYVSVFVGTV 152

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1563 TEDKEKLMEELESVRSSKMAESTEwqEK-------HKELQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQELyaklrs 1635
Cdd:PRK05771   153 PEDKLEELKLESDVENVEYISTDK--GYvyvvvvvLKELSDEVEEELKKLGFERLELEEEGTPSELIREIKEEL------ 224

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1720386946 1636 tesdkREREKQLQDAEqemeemkEKMRKFAKSKQQKILELEE--ENDRLRAEA 1686
Cdd:PRK05771   225 -----EEIEKERESLL-------EELKELAKKYLEELLALYEylEIELERAEA 265
46 PHA02562
endonuclease subunit; Provisional
 2241-2461 3.34e-04

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 46.16  E-value: 3.34e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2241 HDKEIWESKAQT--ELQHHQKAYDKLQEENKELTSQLEDArqlyhdsKNELTKLESELKSLKDQTTDLNNSLEKCKEHEN 2318
Cdd:PHA02562   200 YNKNIEEQRKKNgeNIARKQNKYDELVEEAKTIKAEIEEL-------TDELLNLVMDIEDPSAALNKLNTAAAKIKSKIE 272

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2319 NLEGIIKQQEaDIQNCKfSCEQletDLAASRELTSRLHDEINAKEQKIISLLSGKEEAIQLAVEELHQQhsKEIKELENL 2398
Cdd:PHA02562   273 QFQKVIKMYE-KGGVCP-TCTQ---QISEGPDRITKIKDKLKELQHSLEKLDTAIDELEEIMDEFNEQS--KKLLELKNK 345

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1720386946 2399 LSQEEEENVALEEENKRALEKTNQLTEALEAIKKESFEQKAQLDSFVKSMSSLQDDRDR--IVSD 2461
Cdd:PHA02562   346 ISTNKQSLITLVDKAKKVKAAIEELQAEFVDNAEELAKLQDELDKIVKTKSELVKEKYHrgIVTD 410
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2649-2872 3.56e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.91  E-value: 3.56e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2649 SEIEDQLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLTVTKENKDLMAQIQAFGRSMSSLQDSRDHATEE 2728
Cdd:COG4942     19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE 98

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2729 LGDLKKKYDASLKELAQLkewQDSSREGDVLSQAAFplSTSENVLSRLEKLNQQLTSKDEQLLHLSSELESSHNQVQSIS 2808
Cdd:COG4942     99 LEAQKEELAELLRALYRL---GRQPPLALLLSPEDF--LDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAER 173

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1720386946 2809 KAMTSLQNERDRLWSELEKFRKSEEGKQRAAAPSAASSPAEVQSLKKAMSSLQNDRDRLLKELK 2872
Cdd:COG4942    174 AELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAA 237
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1312-1481 3.76e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 46.45  E-value: 3.76e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1312 ASELAKKSEEVLLLQDQINEQGLEIQNLKAASVEAQAHTELLKQELES--SQLKVAGLEHLKTLQPELDALHKHMGQKEE 1389
Cdd:COG4913    280 ALRLWFAQRRLELLEAELEELRAELARLEAELERLEARLDALREELDEleAQIRGNGGDRLEQLEREIERLERELEERER 359

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1390 EVNYLYGQLSEKEQTLTTVQTEMVEQERLIKALHTQLEMQAKEHEERLKQAQVEICELKKKPTELEEETNAKQQLQRKLQ 1469
Cdd:COG4913    360 RRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIP 439

                          170
                   ....*....|..
gi 1720386946 1470 AALISRKEALKE 1481
Cdd:COG4913    440 ARLLALRDALAE 451
PTZ00121 PTZ00121
MAEBL; Provisional
 682-1196 3.94e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 46.67  E-value: 3.94e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  682 ERLKTQVLELETSLHTAEETYKrnlSEKVKEISSLTQLSEEVKEsAEEARSTLAAVTEERDQLLYQVKELDVLAELRARV 761
Cdd:PTZ00121  1276 EARKADELKKAEEKKKADEAKK---AEEKKKADEAKKKAEEAKK-ADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAE 1351

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  762 QELESSLAEAEKQRGLDYESQRAQHNLLTEQIHSLSIEAKSKD---VKIEALQRELDGVQlqfceQGTQMKTLQSQLEAK 838
Cdd:PTZ00121  1352 AEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADeakKKAEEDKKKADELK-----KAAAAKKKADEAKKK 1426

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  839 EREVREGTERLRDISQEMEGLSQALSQKELEIAKMDQLLLEKQKDVETLQQTIQEKdQQVTELSFSMTEKMVQLNEEKfs 918
Cdd:PTZ00121  1427 AEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEA-KKADEAKKKAEEAKKKADEAK-- 1503

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  919 lgvEIKTLKEQLNLLSRTEEATK----EQVEESGAGSSLKLGHDESGQEGLQQELEL-----------LRKESEQRKRKL 983
Cdd:PTZ00121  1504 ---KAAEAKKKADEAKKAEEAKKadeaKKAEEAKKADEAKKAEEKKKADELKKAEELkkaeekkkaeeAKKAEEDKNMAL 1580

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  984 QAALINRKELLQKVSQLEEELAKVREDSRKEIPFGENERRKLEEDRENRDDPEEWGTSKWREVEASLKQTISEKEVELEG 1063
Cdd:PTZ00121  1581 RKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENK 1660

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1064 IRRDLKEKTAAEEELQA-VVQRMTRDLQSKTKQIDLLQEEVTENQATIQKLVTGTMDAGNGGSAAPVKETAASSPPGAGG 1142
Cdd:PTZ00121  1661 IKAAEEAKKAEEDKKKAeEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAE 1740

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1720386946 1143 EEHWKPElEGRILDLEKDKTQLQKKLQEaliarKAILKKAQEKEKQLKEELREQ 1196
Cdd:PTZ00121  1741 EDKKKAE-EAKKDEEEKKKIAHLKKEEE-----KKAEEIRKEKEAVIEEELDEE 1788
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1704-1915 4.74e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.53  E-value: 4.74e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1704 SSLKEELEKITLEHKTLSKEFEALMAEKDALSEETRNLKLQVEA--QVLKQASLEATEKSDEPKDVIEEVTQAVVGKSQE 1781
Cdd:COG4942     23 AEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAAlaRRIRALEQELAALEAELAELEKEIAELRAELEAQ 102

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1782 RDALSDSAKledsEAILMGDGAKPGV---SETFSSHDDIKNYLQQL-DQLKGRIAELEMEKQKDRELSQALENEKNALLT 1857
Cdd:COG4942    103 KEELAELLR----ALYRLGRQPPLALllsPEDFLDAVRRLQYLKYLaPARREQAEELRADLAELAALRAELEAERAELEA 178

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1720386946 1858 QISAKDSELKLLEEEVTKRTTLNQQIQEELcrvtKLKETAEEEKDDLEERLMNQLAEL 1915
Cdd:COG4942    179 LLAELEEERAALEALKAERQKLLARLEKEL----AELAAELAELQQEAEELEALIARL 232
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 2045-2598 5.16e-04

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 45.98  E-value: 5.16e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2045 LAQAVEHRKKAQAELSSFKILLDDTQSEAARVLADNLKLKKELQSNKESIKSQIKQKDEDLLRRLEQAEEKHRKEKKNMq 2124
Cdd:pfam12128  246 LQQEFNTLESAELRLSHLHFGYKSDETLIASRQEERQETSAELNQLLRTLDDQWKEKRDELNGELSAADAAVAKDRSEL- 324

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2125 EKLDALHR-------EKAHVE-ETLAEIQVSLTRKDQEMKELQGSLDSTLAQLAAFTKSMSS--------LQDDRDRVID 2188
Cdd:pfam12128  325 EALEDQHGafldadiETAAADqEQLPSWQSELENLEERLKALTGKHQDVTAKYNRRRSKIKEqnnrdiagIKDKLAKIRE 404

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2189 EAKKWERRFGDAIQTKEEEVRLKEENCIA-LKDQLRQMAIHMEELKITV------SRLEHDKEIWES---KAQTELQHHQ 2258
Cdd:pfam12128  405 ARDRQLAVAEDDLQALESELREQLEAGKLeFNEEEYRLKSRLGELKLRLnqatatPELLLQLENFDErieRAREEQEAAN 484

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2259 KAYDKLQEENKELTSQLEDARQLYHDSKNELTKLESELKSLKDQ---------------------------------TTD 2305
Cdd:pfam12128  485 AEVERLQSELRQARKRRDQASEALRQASRRLEERQSALDELELQlfpqagtllhflrkeapdweqsigkvispellhRTD 564

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2306 LNNSL-EKCKEHENNLEGI-IKQQEADIQNCKFSCEQLETDLAASRELTSRLHDEINAKEQKiISLLSGKEEAIQLAVEE 2383
Cdd:pfam12128  565 LDPEVwDGSVGGELNLYGVkLDLKRIDVPEWAASEEELRERLDKAEEALQSAREKQAAAEEQ-LVQANGELEKASREETF 643

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2384 LHQQHSKEIKELENLLSQEEEENVALEEENKRALEKTNQLTEALEAikkesfeQKAQLDSFVKSMSSLQDDRDRIVSDYR 2463
Cdd:pfam12128  644 ARTALKNARLDLRRLFDEKQSEKDKKNKALAERKDSANERLNSLEA-------QLKQLDKKHQAWLEEQKEQKREARTEK 716

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2464 QLEERHLSAILEK--DQLIQDAAAENNKLKEEMRGLRSHMD--------------DLNSENAKLDAELVQYRRDLNEVIA 2527
Cdd:pfam12128  717 QAYWQVVEGALDAqlALLKAAIAARRSGAKAELKALETWYKrdlaslgvdpdviaKLKREIRTLERKIERIAVRRQEVLR 796

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1720386946 2528 IKDSQQKQLL---DAQLQQNKELRNECTKLEERLKGLEAE----KQSLQMSSDALQKEKQGLSKEIKNLQTQLTALQE 2598
Cdd:pfam12128  797 YFDWYQETWLqrrPRLATQLSNIERAISELQQQLARLIADtklrRAKLEMERKASEKQQVRLSENLRGLRCEMSKLAT 874
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
2341-2821 5.40e-04

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 45.80  E-value: 5.40e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2341 LETDLAASRELTSRLHDE-INAKEQKiisllsgkeEAIQLAVEElHQQHSKEIKELENLLSQEEEENVALEEENKRALEK 2419
Cdd:PRK02224   211 LESELAELDEEIERYEEQrEQARETR---------DEADEVLEE-HEERREELETLEAEIEDLRETIAETEREREELAEE 280

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2420 TNQLTEALEAIKKESFEQKAQLDSFVKSMSSLQDDRDRIVSDYRQLEERhlsaILEKDQLIQDAAAENNKLKEEMRGLRS 2499
Cdd:PRK02224   281 VRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDR----LEECRVAAQAHNEEAESLREDADDLEE 356

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2500 HMDDLNSENAKLDAELVQYRRDLNEviaikdsqqkqlldaQLQQNKELRNECTKLEERLKGLEAEKQSLQMSSDALQKEK 2579
Cdd:PRK02224   357 RAEELREEAAELESELEEAREAVED---------------RREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREER 421

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2580 QGLSKEIKNLQTQLT----------ALQEEG--------------------------TLGVYHAQLKAKEEEL-QRLNMA 2622
Cdd:PRK02224   422 DELREREAELEATLRtarerveeaeALLEAGkcpecgqpvegsphvetieedrerveELEAELEDLEEEVEEVeERLERA 501

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2623 --LSSSQKRTADLEE------ELVCVQKEATRKVSEIEDQLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKL 2694
Cdd:PRK02224   502 edLVEAEDRIERLEErredleELIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKL 581

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2695 LTVTKEN------KDLMAQIQAFGRSMSSLQDSRDHATeELGDLKKKYdasLKELAQLKEWQDSSREGDVLSQAAFPLST 2768
Cdd:PRK02224   582 AELKERIesleriRTLLAAIADAEDEIERLREKREALA-ELNDERRER---LAEKRERKRELEAEFDEARIEEAREDKER 657

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1720386946 2769 SENVLSRLEKLNQQLTSKDEQLLHLSSELESSHNQVQSISKAMTSLQNERDRL 2821
Cdd:PRK02224   658 AEEYLEQVEEKLDELREERDDLQAEIGAVENELEELEELRERREALENRVEAL 710
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1382-1919 5.45e-04

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 45.83  E-value: 5.45e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1382 KHMGQKEEEVNYLYGQLSEKEQTLTTVQTEMVEQERL------IKALHTQLEMQAKEHEERLKQAQVEICELKKKPTELE 1455
Cdd:PRK03918   200 KELEEVLREINEISSELPELREELEKLEKEVKELEELkeeieeLEKELESLEGSKRKLEEKIRELEERIEELKKEIEELE 279

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1456 E------ETNAKQQLQRKLQAALISRKEALKENKSLQEQLSSARDAVERLTKSLADVESQVSVQNQEKDAVLGKLTILqE 1529
Cdd:PRK03918   280 EkvkelkELKEKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEEL-E 358

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1530 ERDKLIAEMDRFLLENQSLSG-----SCESLKLALGGLTEDKEKLMEELESVRsskmAESTEWQEKHKELQKEYEVL--- 1601
Cdd:PRK03918   359 ERHELYEEAKAKKEELERLKKrltglTPEKLEKELEELEKAKEEIEEEISKIT----ARIGELKKEIKELKKAIEELkka 434

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1602 ---------LQSYENVSNEAERIQHVVESVRQEKQELYAKLRSTESDKREREKQLQDAEQEMEEMKEKMRKFAKSKQQKI 1672
Cdd:PRK03918   435 kgkcpvcgrELTEEHRKELLEEYTAELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKLKELAEQLKELEEKLKK 514

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1673 LELEEendrLRAEAQPVGGTGESMEALLSSNSSLKEELEKItlehKTLSKEFEALMAEKDALSEETRNLKLQVEAQVLKQ 1752
Cdd:PRK03918   515 YNLEE----LEKKAEEYEKLKEKLIKLKGEIKSLKKELEKL----EELKKKLAELEKKLDELEEELAELLKELEELGFES 586

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1753 ASlEATEKSDEPKDVIEEVTQAVVGKSQERDALSDSAKLEDSEailmgDGAKPGVSETFSSHDDIKNYLQQLDQL--KGR 1830
Cdd:PRK03918   587 VE-ELEERLKELEPFYNEYLELKDAEKELEREEKELKKLEEEL-----DKAFEELAETEKRLEELRKELEELEKKysEEE 660

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1831 IAELEMEKQKDRELSQALENEKNALLTQISAKDSELKLLEEEVTKRTTLNQQIQ---EELCRVTKLKETAEEEKDDLEER 1907
Cdd:PRK03918   661 YEELREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKEELEEREKAKKELEkleKALERVEELREKVKKYKALLKER 740

                          570
                   ....*....|..
gi 1720386946 1908 LMNQLAELNGSI 1919
Cdd:PRK03918   741 ALSKVGEIASEI 752
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
166-374 5.54e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 46.06  E-value: 5.54e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  166 QAQLDQSEQASQLDKSSAEMEDFVLMKQQLQEKEELISTLQTQlsqtQAEQAAQVVREKDARFETQVRLHEDELLQLvtq 245
Cdd:COG4913    242 EALEDAREQIELLEPIRELAERYAAARERLAELEYLRAALRLW----FAQRRLELLEAELEELRAELARLEAELERL--- 314

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  246 sdvetemQQKLRVMQRKLEEHEEALLGR-AQVVDLLQKELTSAEQRNQVLSQQLQLLEAEHNTLKNTMETERQESKTLME 324
Cdd:COG4913    315 -------EARLDALREELDELEAQIRGNgGDRLEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRA 387

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|
gi 1720386946  325 KVELEVAERKLSFHNLQEEMHQLQGQLERAGQAQADLETQYSALQQRHKT 374
Cdd:COG4913    388 EAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSN 437
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1578-2037 5.54e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 45.53  E-value: 5.54e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1578 SSKMAESTEWQEKHKELQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQ--ELYAKLRSTESDKREREKQLQDAEQEME 1655
Cdd:COG4717     77 EEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQllPLYQELEALEAELAELPERLEELEERLE 156

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1656 EMkekmrkfaKSKQQKILELEEENDRLRAEAQpvggtgesmEALLSSNSSLKEELEKITLEHKTLSKEFEALMAEKDALS 1735
Cdd:COG4717    157 EL--------RELEEELEELEAELAELQEELE---------ELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQ 219

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1736 EETRNLKLQVEAQVLKQASLEATEKSDEPKDVIEEVTQAVVGKSQERDALSDSAKLEDSEAILMGDGAKPGVSETFSSHD 1815
Cdd:COG4717    220 EELEELEEELEQLENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKAS 299

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1816 DIknylQQLDQLKGRIAELEMEKQKDRELSQALENEKNALLTQISAKDSELKLLEEEVTKRTTLNQQIQEELCRVTK--- 1892
Cdd:COG4717    300 LG----KEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQEIaal 375

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1893 LKETAEEEKDDLEERLM---------NQLAELNGSIGNYYQDVTD--AQIKNEQLESEMRNLQRCVSELEEEKQQLVKEK 1961
Cdd:COG4717    376 LAEAGVEDEEELRAALEqaeeyqelkEELEELEEQLEELLGELEEllEALDEEELEEELEELEEELEELEEELEELREEL 455

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1720386946 1962 TKVESEIRkeymekiqgaqkgpaNKSHAKELQELLREKQQEVKQLQkdciRYLERISALEKTVKALEFVHTESQKD 2037
Cdd:COG4717    456 AELEAELE---------------QLEEDGELAELLQELEELKAELR----ELAEEWAALKLALELLEEAREEYREE 512
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1366-2179 5.59e-04

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 45.88  E-value: 5.59e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1366 GLEHLKTLQPELDALHKHMGQKEEEVNYLY-GQLSEKEQTLTTVQTEMVEQERLIKALHTQLEMQAKEHEERLKQAQVEI 1444
Cdd:pfam15921   72 GKEHIERVLEEYSHQVKDLQRRLNESNELHeKQKFYLRQSVIDLQTKLQEMQMERDAMADIRRRESQSQEDLRNQLQNTV 151

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1445 CELKKKPTELEEETNAKQQLQRKLQAALISRKEALKENKSLQEQLSSARDaverltKSLADVESQVSVQNQEKDAVLGKl 1524
Cdd:pfam15921  152 HELEAAKCLKEDMLEDSNTQIEQLRKMMLSHEGVLQEIRSILVDFEEASG------KKIYEHDSMSTMHFRSLGSAISK- 224

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1525 tILQEERDKLIAEMDR-FLLENQSLSGSCES---LKLALGGLTEDKEKLMEELESVRSSKMAESTEWQEKHKELQKEYEV 1600
Cdd:pfam15921  225 -ILRELDTEISYLKGRiFPVEDQLEALKSESqnkIELLLQQHQDRIEQLISEHEVEITGLTEKASSARSQANSIQSQLEI 303

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1601 LLQSYENVSNEAERIQHVVES-VRQEKQELYAKLRSTESDKREREKQLQDAEQEMEEMKEKMRKFAKS------------ 1667
Cdd:pfam15921  304 IQEQARNQNSMYMRQLSDLEStVSQLRSELREAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQEsgnlddqlqkll 383

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1668 ----KQQKILELEEENDRLRAEAQpvggTGESMeallsSNSSLKEELEKITLEHKTLSKEFEALMAEKDALSEETRNLKL 1743
Cdd:pfam15921  384 adlhKREKELSLEKEQNKRLWDRD----TGNSI-----TIDHLRRELDDRNMEVQRLEALLKAMKSECQGQMERQMAAIQ 454

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1744 QVEAQVLKQASLEATEKSDEP--KDVIEEVT-QAVVGKSQERDALSDSAKLEDSEAILMGDGAKpgvSETFSSHDDIKny 1820
Cdd:pfam15921  455 GKNESLEKVSSLTAQLESTKEmlRKVVEELTaKKMTLESSERTVSDLTASLQEKERAIEATNAE---ITKLRSRVDLK-- 529

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1821 LQQLDQLKGRIAELemekqkdrelsQALENEKNALLTQISAKDSELKLLEEEVTKRTTLNQQiqeelcrVTKLKETAEEE 1900
Cdd:pfam15921  530 LQELQHLKNEGDHL-----------RNVQTECEALKLQMAEKDKVIEILRQQIENMTQLVGQ-------HGRTAGAMQVE 591

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1901 KDDLEERLMNQLAELNgsignyyqdvtDAQIKNEQLESEMRNLQRCVSELEEEKQQLV---KEKTKVESEIRKEYMEKIQ 1977
Cdd:pfam15921  592 KAQLEKEINDRRLELQ-----------EFKILKDKKDAKIRELEARVSDLELEKVKLVnagSERLRAVKDIKQERDQLLN 660

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1978 GAQKGPANKSHAKELQELL----REKQQEVKQLQKDCIRYLERI-SALEKTVKALEFVHTESQKDLDVTKGNLAQAVEHR 2052
Cdd:pfam15921  661 EVKTSRNELNSLSEDYEVLkrnfRNKSEEMETTTNKLKMQLKSAqSELEQTRNTLKSMEGSDGHAMKVAMGMQKQITAKR 740

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2053 KKAQAELSSFKILLDDTQSeaARVLADNLKLKKELQSNKESIKSQIKQKDEDLLRRLEQAEEKHRKEKKNMQEKLDalhr 2132
Cdd:pfam15921  741 GQIDALQSKIQFLEEAMTN--ANKEKHFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANMEVALD---- 814

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1720386946 2133 eKAHVEetLAEIQVSLTRKDQE-----------MKELQG-------SLDSTLAQLAAFTKSMSSL 2179
Cdd:pfam15921  815 -KASLQ--FAECQDIIQRQEQEsvrlklqhtldVKELQGpgytsnsSMKPRLLQPASFTRTHSNV 876
MAD pfam05557
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ...
 1823-2312 6.06e-04

Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.


Pssm-ID: 461677 [Multi-domain]  Cd Length: 660  Bit Score: 45.50  E-value: 6.06e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1823 QLDQLKGRIAELEMEKQKDRELSQALENEKNALLTQISAKDSELKLLEEEVTKRTTLNQQIQEELCRVTKLKETAEEEKD 1902
Cdd:pfam05557   10 RLSQLQNEKKQMELEHKRARIELEKKASALKRQLDRESDRNQELQKRIRLLEKREAEAEEALREQAELNRLKKKYLEALN 89

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1903 DLEERLMNQLAELNGSIGNYYQDVTDAQIKNEQLESEmrnLQRCVSELEEEKQQLVKEKTKVEseirkEYMEKIQGAQKG 1982
Cdd:pfam05557   90 KKLNEKESQLADAREVISCLKNELSELRRQIQRAELE---LQSTNSELEELQERLDLLKAKAS-----EAEQLRQNLEKQ 161

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1983 P-ANKSHAKELQELLREKQQEV--KQLQKDCIRYLERISALEKTVKALEfvhtESQKDLDVTKGNLAQAVEHRKKAQAEL 2059
Cdd:pfam05557  162 QsSLAEAEQRIKELEFEIQSQEqdSEIVKNSKSELARIPELEKELERLR----EHNKHLNENIENKLLLKEEVEDLKRKL 237

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2060 SSFkillDDTQSEAARVLADNLKLKKELQSNKESIKSQIKQ--KDEDLLRRLEQAEekhrKEKKNMQEKLDALHREKAHV 2137
Cdd:pfam05557  238 ERE----EKYREEAATLELEKEKLEQELQSWVKLAQDTGLNlrSPEDLSRRIEQLQ----QREIVLKEENSSLTSSARQL 309

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2138 EETLAEIQVSLTRKDQEMKELQGSLDSTLAQLAAFTKSMSSLQDDRDRVIDEAKKWerrfgDAIQTKEEEVRLKEENCIA 2217
Cdd:pfam05557  310 EKARRELEQELAQYLKKIEDLNKKLKRHKALVRRLQRRVLLLTKERDGYRAILESY-----DKELTMSNYSPQLLERIEE 384

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2218 LKDQLRQMAIHMEELKITVSRLEHDKEIWESKAQTELQHHQKAydKLQEENKELTSQLEDARQLYHdsknELTKLESELK 2297
Cdd:pfam05557  385 AEDMTQKMQAHNEEMEAQLSVAEEELGGYKQQAQTLERELQAL--RQQESLADPSYSKEEVDSLRR----KLETLELERQ 458

                          490
                   ....*....|....*
gi 1720386946 2298 SLKDQTTDLNNSLEK 2312
Cdd:pfam05557  459 RLREQKNELEMELER 473
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1929-2383 6.34e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 45.68  E-value: 6.34e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1929 AQIKNEQLESEMRNLQRCVSELEEEKQQLVKEKTKVESEIRkEYMEKIQGAQkgpankshAKELQELlrekQQEVKQLQK 2008
Cdd:COG4913    286 AQRRLELLEAELEELRAELARLEAELERLEARLDALREELD-ELEAQIRGNG--------GDRLEQL----EREIERLER 352

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2009 DCIRYLERISALEKTVKALEFVHTESQKDLdvtKGNLAQAVEHRKKAQAELSSfkilLDDTQSEAARVLADNLKLKKELQ 2088
Cdd:COG4913    353 ELEERERRRARLEALLAALGLPLPASAEEF---AALRAEAAALLEALEEELEA----LEEALAEAEAALRDLRRELRELE 425

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2089 SNKESI---KSQIKQKDEDLLRRLEQA-----------------------------------------EEKHRK------ 2118
Cdd:COG4913    426 AEIASLerrKSNIPARLLALRDALAEAlgldeaelpfvgelievrpeeerwrgaiervlggfaltllvPPEHYAaalrwv 505

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2119 EKKNMQEKLDALHREKAHVEETLAEIQV-SLTRK-DQEMKELQGSLDSTLAQLAAFTK--SMSSLQDDRDRV-------- 2186
Cdd:COG4913    506 NRLHLRGRLVYERVRTGLPDPERPRLDPdSLAGKlDFKPHPFRAWLEAELGRRFDYVCvdSPEELRRHPRAItragqvkg 585

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2187 ------IDEAKKWERR--FG----DAIQTKEEEVRLKEENCIALKDQLRQMAIHMEELKITVSRLEHDKEIWESK----- 2249
Cdd:COG4913    586 ngtrheKDDRRRIRSRyvLGfdnrAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEidvas 665

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2250 AQTELQHHQKAYDKLQEEN---KELTSQLEDARQLYHDSKNELTKLESELKSLKDQTTDLNNSLEKCKEHENNLEGIIKQ 2326
Cdd:COG4913    666 AEREIAELEAELERLDASSddlAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARL 745

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1720386946 2327 QEAdiqnckfscEQLETDLAA--SRELTSRLHDEINAKEQKIISLLSGKEEAIQLAVEE 2383
Cdd:COG4913    746 ELR---------ALLEERFAAalGDAVERELRENLEERIDALRARLNRAEEELERAMRA 795
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 679-1235 8.23e-04

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 45.44  E-value: 8.23e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  679 GELERLKTQVLELETSLHTAE---ETYKRNLSEKVKEISSLTQLSEEVKESAEEARSTLAAVTEERDQLLYQVKEL-DVL 754
Cdd:TIGR02169  287 EEQLRVKEKIGELEAEIASLErsiAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELkEEL 366

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  755 AELRARVQELESSLAE-----AEKQRGLD------YESQRAQHNL------LTEQIHSLSIEAKSKDVKIEALQRELDGV 817
Cdd:TIGR02169  367 EDLRAELEEVDKEFAEtrdelKDYREKLEklkreiNELKRELDRLqeelqrLSEELADLNAAIAGIEAKINELEEEKEDK 446

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  818 QLQFCEQGTQMKTLQSQLEAKEREVREGTERLRDISQEMEGLSQALSQKE------------------------------ 867
Cdd:TIGR02169  447 ALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEaqaraseervrggraveevlkasiqgvhgt 526

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  868 --------------LEIAKMDQLLLEKQKDVETLQQTIQ-EKDQQVTELSFSMTEKMVQLNEEKfSLGVEIKTLKEQLNL 932
Cdd:TIGR02169  527 vaqlgsvgeryataIEVAAGNRLNNVVVEDDAVAKEAIElLKRRKAGRATFLPLNKMRDERRDL-SILSEDGVIGFAVDL 605

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  933 L--------------------SRTEEATK------------EQVEESGA--GSSLKLGHDESGQ--------------EG 964
Cdd:TIGR02169  606 VefdpkyepafkyvfgdtlvvEDIEAARRlmgkyrmvtlegELFEKSGAmtGGSRAPRGGILFSrsepaelqrlrerlEG 685

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  965 LQQELELLRKESEQRKRKLQAALINRKELLQKVSQLEEELAKVREDSRKEIPFGENERRKLEEdrenrddpeewgtskwr 1044
Cdd:TIGR02169  686 LKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSS----------------- 748

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1045 eveasLKQTISEKEVELEGIRRDLKEKTAAEEELQAVVQRMTRDL-----QSKTKQIDLLQEEVTENQATIQKLVTGTmd 1119
Cdd:TIGR02169  749 -----LEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLshsriPEIQAELSKLEEEVSRIEARLREIEQKL-- 821

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1120 agngGSAAPVKETAASSppgaggeehwKPELEGRILDLEKDKTQLQKKlQEALIARKAilkKAQEKEKQLKEELREQKDA 1199
Cdd:TIGR02169  822 ----NRLTLEKEYLEKE----------IQELQEQRIDLKEQIKSIEKE-IENLNGKKE---ELEEELEELEAALRDLESR 883

                          650       660       670
                   ....*....|....*....|....*....|....*.
gi 1720386946 1200 YHHLQGQFHEQNKEKENIADQLRQLQCQARESIDRQ 1235
Cdd:TIGR02169  884 LGDLKKERDELEAQLRELERKIEELEAQIEKKRKRL 919
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
704-1116 8.26e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 45.14  E-value: 8.26e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  704 RNLSEKVKEISSLTQLSEEVKESAEEARSTLAAVTEERDQLLYQVKELDVLAELRARVQELESSLAEAE--KQRGLDYES 781
Cdd:COG4717     81 KEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEALEAELAELPERLEelEERLEELRE 160

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  782 QRAQHNLLTEQIHSLSIEAKskdvkiEALQRELDGVQLQFCEQGTQMKTLQSQLEAKEREVREGTERLRDISQEMEGLSQ 861
Cdd:COG4717    161 LEEELEELEAELAELQEELE------ELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLEN 234

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  862 ALS----QKELEIAKMDQLLLEKQKDVETLQQTIQEKDQQVTELSFSMTEKMV----QLNEEKFSLGVEIKTLKEQLNLL 933
Cdd:COG4717    235 ELEaaalEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLAllflLLAREKASLGKEAEELQALPALE 314

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  934 SRTEEATKEQVEESGAGSSLKLGHDESGQEGLQQELELLRK-ESEQRKRKLQAALINRKELLQKVSQLEEELAKVREDSR 1012
Cdd:COG4717    315 ELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREaEELEEELQLEELEQEIAALLAEAGVEDEEELRAALEQA 394

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1013 KEIPFGENERRKLEEDRENRDDPEEWGTSKWreVEASLKQTISEKEVELEGIRRDLKEKTAAEEELQAVVQRMTRD--LQ 1090
Cdd:COG4717    395 EEYQELKEELEELEEQLEELLGELEELLEAL--DEEELEEELEELEEELEELEEELEELREELAELEAELEQLEEDgeLA 472

                          410       420
                   ....*....|....*....|....*.
gi 1720386946 1091 SKTKQIDLLQEEVTENQATIQKLVTG 1116
Cdd:COG4717    473 ELLQELEELKAELRELAEEWAALKLA 498
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 699-1105 8.63e-04

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 45.10  E-value: 8.63e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  699 EETYKRNLSEKVKEISSLTQLSEEVKESAEEARSTLAAVTEERDQLLYQVK-ELDVLAELRARVQELESSLAEAEKQRGL 777
Cdd:pfam05483  228 EEEYKKEINDKEKQVSLLLIQITEKENKMKDLTFLLEESRDKANQLEEKTKlQDENLKELIEKKDHLTKELEDIKMSLQR 307

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  778 DYESQRAQHNLLTEQIHSLSIEAKSKDVKIEALQRE-------LDGVQLQFCEQGTQMKTLQSQLEAKEREVREGTERLR 850
Cdd:pfam05483  308 SMSTQKALEEDLQIATKTICQLTEEKEAQMEELNKAkaahsfvVTEFEATTCSLEELLRTEQQRLEKNEDQLKIITMELQ 387

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  851 DISQEMEGLSQALSQKELEIAKM------DQLLLEKQKDVETLQQTIQEKDQQVTELSFSMTEKMVQLNEEKFSLGV-EI 923
Cdd:pfam05483  388 KKSSELEEMTKFKNNKEVELEELkkilaeDEKLLDEKKQFEKIAEELKGKEQELIFLLQAREKEIHDLEIQLTAIKTsEE 467

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  924 KTLKEQLNLLSRTEEATKEQVEESGAGSSLKLGHDESGQEGLQQELELLRKESE--QRKRKLQAALINRKELLQKVSQLE 1001
Cdd:pfam05483  468 HYLKEVEDLKTELEKEKLKNIELTAHCDKLLLENKELTQEASDMTLELKKHQEDiiNCKKQEERMLKQIENLEEKEMNLR 547

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1002 EELAKVREDSRKEipfGENERRKLEEDRENRDDPEEWGTSKWREVEASlkqtisekEVELEGIRRDLKEKTAAEEELQAV 1081
Cdd:pfam05483  548 DELESVREEFIQK---GDEVKCKLDKSEENARSIEYEVLKKEKQMKIL--------ENKCNNLKKQIENKNKNIEELHQE 616

                          410       420
                   ....*....|....*....|....
gi 1720386946 1082 VQRMTRDLQSKTKQIDLLQEEVTE 1105
Cdd:pfam05483  617 NKALKKKGSAENKQLNAYEIKVNK 640
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 684-1105 1.03e-03

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 45.01  E-value: 1.03e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  684 LKTQVLELE---TSLHTAEETYKRNLSEKVKEISSLTQLSEEVKESAEEARSTLAAVTEERDQLLYQVKELDvlaelrAR 760
Cdd:TIGR04523  216 LESQISELKkqnNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELE------KQ 289

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  761 VQELESSLAEAEKQRGLDYESQ-RAQHNLLTEQIHSLSIEAKSKDVKIEALQRELDGVQLQFCEQGTQMKTLQSQLEAKE 839
Cdd:TIGR04523  290 LNQLKSEISDLNNQKEQDWNKElKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQ 369

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  840 REVREGTERLRDISQEMEGLSQALSQKELEIAKMDQLLLEKQKDVETLQQTIQEKDQQVTELSfsmtEKMVQLNEEKFSL 919
Cdd:TIGR04523  370 NEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLK----ETIIKNNSEIKDL 445

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  920 GVEIKTLKEQLNLLSRTEEATKEQVEESgagsslklghdESGQEGLQQELELLRKESEQRKRKLQAALINRKELLQKVSQ 999
Cdd:TIGR04523  446 TNQDSVKELIIKNLDNTRESLETQLKVL-----------SRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKD 514

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1000 LEEELAKVREDSRKEipfgenERRKLEEDRENRDDPEEWGTSKWREVEASLKQTISEKEVELEGIRRDLKEKTAAEEELQ 1079
Cdd:TIGR04523  515 LTKKISSLKEKIEKL------ESEKKEKESKISDLEDELNKDDFELKKENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQ 588

                          410       420
                   ....*....|....*....|....*.
gi 1720386946 1080 AVVQRMTRDLQSKTKQIDLLQEEVTE 1105
Cdd:TIGR04523  589 ELIDQKEKEKKDLIKEIEEKEKKISS 614
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 1896-2143 1.08e-03

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 44.92  E-value: 1.08e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1896 TAEEEKDDLEERLMN----QLAELNGSIGNYYqdvtdaqikNEQLESEMRNLQRCVSELEEEKQqlvKEKTKVESEIRKE 1971
Cdd:PRK05771    13 TLKSYKDEVLEALHElgvvHIEDLKEELSNER---------LRKLRSLLTKLSEALDKLRSYLP---KLNPLREEKKKVS 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1972 YMEKIQGAQKGPANKShakELQELLREKQQEVKQLQkdcirylERISALEKTVKALEFVhtesqKDLDV------TKGNL 2045
Cdd:PRK05771    81 VKSLEELIKDVEEELE---KIEKEIKELEEEISELE-------NEIKELEQEIERLEPW-----GNFDLdlslllGFKYV 145

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2046 AQAVEHRKKAQAELSS--------------------FKILLDDTQSEAARVLADNLKLKKELQ---------SNKESIKS 2096
Cdd:PRK05771   146 SVFVGTVPEDKLEELKlesdvenveyistdkgyvyvVVVVLKELSDEVEEELKKLGFERLELEeegtpseliREIKEELE 225

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*..
gi 1720386946 2097 QIKQKDEDLLRRLEQAEEKHRKEKKNMQEKLDALhREKAHVEETLAE 2143
Cdd:PRK05771   226 EIEKERESLLEELKELAKKYLEELLALYEYLEIE-LERAEALSKFLK 271
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 826-1030 1.21e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 44.05  E-value: 1.21e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  826 TQMKTLQSQLEAKEREVREGTERLRDISQEMEGLSQALSQKELEIAKMDQLLLEKQKDVETLQQTIQEKDQQVTELSFSM 905
Cdd:COG3883     16 PQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARAL 95

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  906 TEKMVQLNEEKFSLGVE-IKTLKEQLNLLSRTEEATKEQVEESGAgSSLKLGHDESGQEGLQQELELLRKESEQRKRKLQ 984
Cdd:COG3883     96 YRSGGSVSYLDVLLGSEsFSDFLDRLSALSKIADADADLLEELKA-DKAELEAKKAELEAKLAELEALKAELEAAKAELE 174

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*.
gi 1720386946  985 AALINRKELLQKVSQLEEELAKVREDSRKEIPFGENERRKLEEDRE 1030
Cdd:COG3883    175 AQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAA 220
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1370-1753 1.23e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 44.37  E-value: 1.23e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1370 LKTLQPELDALHKHMGQK---------------------EEEVNYLYGQLSEKEQTLTTVQTEMVEQERLIKALHT---- 1424
Cdd:COG4717     48 LERLEKEADELFKPQGRKpelnlkelkeleeelkeaeekEEEYAELQEELEELEEELEELEAELEELREELEKLEKllql 127

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1425 --------QLEMQAKEHEERLKQAQVEICELKKKPTELEEETNAKQQLQRKLQAALISRKEALKEN-KSLQEQLSSARDA 1495
Cdd:COG4717    128 lplyqeleALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEElQDLAEELEELQQR 207

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1496 VERLTKSLADVESQVSVQNQEKDAVLGKLTILQEERDKLIAEMDRF----LLENQSLSGSCESLKLALGGL--------- 1562
Cdd:COG4717    208 LAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLLLLiaaaLLALLGLGGSLLSLILTIAGVlflvlglla 287

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1563 ---------TEDKEKLMEELESVRSSKMAESTEWQEKHKELQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQELyakl 1633
Cdd:COG4717    288 llflllareKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEEL---- 363

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1634 rSTESDKREREKQLQDAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEAqpvggTGESMEALLSSNSSLKEELEKI 1713
Cdd:COG4717    364 -QLEELEQEIAALLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELL-----GELEELLEALDEEELEEELEEL 437

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|
gi 1720386946 1714 TLEHKTLSKEFEALMAEKDALSEETRNLKLQVEAQVLKQA 1753
Cdd:COG4717    438 EEELEELEEELEELREELAELEAELEQLEEDGELAELLQE 477
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 1822-1975 1.25e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 43.37  E-value: 1.25e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1822 QQLDQLKGRIAELEMEKQKDRELSQALENEKNALLTQISAKDSELKLLEEEVTKRTTLNQQIQEELCRVTKLKE------ 1895
Cdd:COG1579     17 SELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVRNNKEyealqk 96

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1896 ---TAEEEKDDLEERLMNQLAELNGSIGNYYQDVTDAQIKNEQLESEMRNLQRCVSELEEEKQQLVKEKTKVESEIRKEY 1972
Cdd:COG1579     97 eieSLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAEREELAAKIPPEL 176


                   ...
gi 1720386946 1973 MEK 1975
Cdd:COG1579    177 LAL 179
HMMR_N pfam15905
Hyaluronan mediated motility receptor N-terminal; HMMR_N is the N-terminal region of ...
 864-1113 1.29e-03

Hyaluronan mediated motility receptor N-terminal; HMMR_N is the N-terminal region of eukaryotic hyaluronan-mediated motility receptor proteins. The protein is functionally associated with BRCA1 and thus predicted to be a common, low-penetrance breast cancer candidate.


Pssm-ID: 464932 [Multi-domain]  Cd Length: 329  Bit Score: 44.03  E-value: 1.29e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  864 SQKELEIAKmDQLLLEKQKDVETLQQTIQEKDQQVTELSFSMTE-KMVQLNEEKFSLGVEIKTLKEQLNLLSRTEEATKE 942
Cdd:pfam15905   65 SQKNLKESK-DQKELEKEIRALVQERGEQDKRLQALEEELEKVEaKLNAAVREKTSLSASVASLEKQLLELTRVNELLKA 143

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  943 QVEESGAGSSLKLGHDESGQegLQQELELLRKE----SEQRKRKLQAALINRKELLQKVSQLEEELAKVREDSRKE---- 1014
Cdd:pfam15905  144 KFSEDGTQKKMSSLSMELMK--LRNKLEAKMKEvmakQEGMEGKLQVTQKNLEHSKGKVAQLEEKLVSTEKEKIEEkset 221

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1015 ------IPFGENERRKLEEDRENRDDPEEWGTSKWREVEaSLKQTISEKEVELEGIRRDLKEKTA-AEEELQAVVQRMTR 1087
Cdd:pfam15905  222 eklleyITELSCVSEQVEKYKLDIAQLEELLKEKNDEIE-SLKQSLEEKEQELSKQIKDLNEKCKlLESEKEELLREYEE 300

                          250       260
                   ....*....|....*....|....*.
gi 1720386946 1088 DLQSKTKQIDLLQEEVTENQATIQKL 1113
Cdd:pfam15905  301 KEQTLNAELEELKEKLTLEEQEHQKL 326
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 2608-3051 1.29e-03

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 44.83  E-value: 1.29e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2608 QLKAKEEELQRLNMALSSSQKRTADLEEELVCVQKEATRKVSEIEDQLKKELKHLHHDAGIMRNETETAEERVAELARDL 2687
Cdd:pfam12128  252 TLESAELRLSHLHFGYKSDETLIASRQEERQETSAELNQLLRTLDDQWKEKRDELNGELSAADAAVAKDRSELEALEDQH 331

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2688 VEMEQKLLTVTKENKDLMAQIQAfgrSMSSLQDSRDHATEELGDLKKKYDA--------SLKELAQLKEWQDSSREGDVL 2759
Cdd:pfam12128  332 GAFLDADIETAAADQEQLPSWQS---ELENLEERLKALTGKHQDVTAKYNRrrskikeqNNRDIAGIKDKLAKIREARDR 408

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2760 SQAAfplstSENVLSRLE-----KLNQQLTSKDEQLLHLSS---ELESSHNQVQSISKAMTSLQNERDRL---WSELEKF 2828
Cdd:pfam12128  409 QLAV-----AEDDLQALEselreQLEAGKLEFNEEEYRLKSrlgELKLRLNQATATPELLLQLENFDERIeraREEQEAA 483

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2829 RKSEEGKQRAAAPSAASSPAEVQSLKKAMSSLQNDRDRllkeLKNLQQQYLQMSQEMTELRPLKAQLQEsQDQTKAL--- 2905
Cdd:pfam12128  484 NAEVERLQSELRQARKRRDQASEALRQASRRLEERQSA----LDELELQLFPQAGTLLHFLRKEAPDWE-QSIGKVIspe 558

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2906 ---------QVMEEELRQENLSWQHELRQLRMEKNSWELHERRMKE---QFLMAISDKDQQLGHLQSLLRELRSSSQAQI 2973
Cdd:pfam12128  559 llhrtdldpEVWDGSVGGELNLYGVKLDLKRIDVPEWAASEEELRErldKAEEALQSAREKQAAAEEQLVQANGELEKAS 638

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1720386946 2974 LSTQYQRQASPETSASLdgsQKLVYETELLRTQLNDSLKEihqkelRIQQLNSKFSQLLEEKNVLSTQLSDASQSLRE 3051
Cdd:pfam12128  639 REETFARTALKNARLDL---RRLFDEKQSEKDKKNKALAE------RKDSANERLNSLEAQLKQLDKKHQAWLEEQKE 707
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 684-1414 1.35e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 44.67  E-value: 1.35e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  684 LKTQVLELETSLHTAE-ETYKRNLSEKVKEISSLTQLSEEVKESAEEARSTLAAVTEERDQLLYQVKEL--DVLAELRAR 760
Cdd:TIGR02169  216 LLKEKREYEGYELLKEkEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLgeEEQLRVKEK 295

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  761 VQELESSLAEAE------KQRGLDYESQRAQhnlLTEQIHSLSIEAKSKDVKIEALQRELDGVQLQFCEQGTQMKTLQSQ 834
Cdd:TIGR02169  296 IGELEAEIASLErsiaekERELEDAEERLAK---LEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAE 372

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  835 LEAKEREVREGTERLRDISQEMEGLSQALSQKELEIAKMDQLLLEKQKDVETLQQTIQEKDQQVTELSFSMTEK------ 908
Cdd:TIGR02169  373 LEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKaleikk 452

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  909 -----------MVQLNEEKFSLGVEIKTLKEQLNLLSR---TEEATKEQVEESGAGSSLKLGHDESGQEGLQQELELLRK 974
Cdd:TIGR02169  453 qewkleqlaadLSKYEQELYDLKEEYDRVEKELSKLQRelaEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLGS 532

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  975 ESEQRKRKLQAALINRKELL----QKVSQLEEELAKVREDSRKE-IPFGENERRKLEEDRENRD------------DPEE 1037
Cdd:TIGR02169  533 VGERYATAIEVAAGNRLNNVvvedDAVAKEAIELLKRRKAGRATfLPLNKMRDERRDLSILSEDgvigfavdlvefDPKY 612

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1038 WGTSKW--------REVEASLKQTISEKEVELEGirrDLKEKTAA--------------EEELQAVVQRMTRDLQSKTKQ 1095
Cdd:TIGR02169  613 EPAFKYvfgdtlvvEDIEAARRLMGKYRMVTLEG---ELFEKSGAmtggsraprggilfSRSEPAELQRLRERLEGLKRE 689

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1096 IDLLQEEVTEnqatIQKLVTGTMDAGnggSAAPVKETAASSPPGAGGEEHWKpeLEGRILDLEKDKTQLQKKLQEALIAR 1175
Cdd:TIGR02169  690 LSSLQSELRR----IENRLDELSQEL---SDASRKIGEIEKEIEQLEQEEEK--LKERLEELEEDLSSLEQEIENVKSEL 760

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1176 KAILKKAQEKEKQLKEELREQKDAYHHLQGQFHEQ-NKEKENIADQLRQLQCQAREsIDRQLPgtgqqepgppAPSLEGI 1254
Cdd:TIGR02169  761 KELEARIEELEEDLHKLEEALNDLEARLSHSRIPEiQAELSKLEEEVSRIEARLRE-IEQKLN----------RLTLEKE 829

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1255 SLEDTEPASESDLHAAQPSPPGETAALQA-TVSVAQIQAQLKEMEVEKEELELKVSSIASELAKKSEEVLLLQDQINEQG 1333
Cdd:TIGR02169  830 YLEKEIQELQEQRIDLKEQIKSIEKEIENlNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELE 909

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1334 LEIQNLKAASVEAQAHTELLKQELESSQLKVAGLEHLKTLQPELDALHKHMGQKEEEVNYL-----------------YG 1396
Cdd:TIGR02169  910 AQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELSLEDVQAELQRVEEEIRALepvnmlaiqeyeevlkrLD 989

                          810
                   ....*....|....*...
gi 1720386946 1397 QLSEKEQTLTTVQTEMVE 1414
Cdd:TIGR02169  990 ELKEKRAKLEEERKAILE 1007
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1048-1253 1.36e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.98  E-value: 1.36e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1048 ASLKQTISEKEVELEGIRRDLKEKTAAEEELQAVVQRMTRDLQSKTKQIDLLQEEVTENQATIQKLVTGTMDAGNGGSAA 1127
Cdd:COG4942     44 AALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELAELLRALYRLGRQPPLA 123

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1128 PVkeTAASSPPGAGGEEHW----KPELEGRILDLEKDKTQLQKKLQEALIARK---AILKKAQEKEKQLKEELREQKDAY 1200
Cdd:COG4942    124 LL--LSPEDFLDAVRRLQYlkylAPARREQAEELRADLAELAALRAELEAERAeleALLAELEEERAALEALKAERQKLL 201

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1720386946 1201 HHLQGQFHEQNKEKENIADQLRQLQcQARESIDRQLPGTGQQEPGPPAPSLEG 1253
Cdd:COG4942    202 ARLEKELAELAAELAELQQEAEELE-ALIARLEAEAAAAAERTPAAGFAALKG 253
PRK12704 PRK12704
phosphodiesterase; Provisional
 1161-1236 1.39e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 44.38  E-value: 1.39e-03
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1720386946 1161 KTQLQKKLQEALIARKAILKKAQEKEKQLKEE-LREQKDAYHHLQGQFHEQNKEKEN-IADQLRQLQcQARESIDRQL 1236
Cdd:PRK12704    26 KKIAEAKIKEAEEEAKRILEEAKKEAEAIKKEaLLEAKEEIHKLRNEFEKELRERRNeLQKLEKRLL-QKEENLDRKL 102
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 753-1374 1.39e-03

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 44.72  E-value: 1.39e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  753 VLAELRARVQELESSLAEAEKQ-RGLDYESQRAQHNLLteQIHSLSIEAKSKDVKIEalqreLDGVQLQFCEQGTQMKTL 831
Cdd:pfam15921  225 ILRELDTEISYLKGRIFPVEDQlEALKSESQNKIELLL--QQHQDRIEQLISEHEVE-----ITGLTEKASSARSQANSI 297

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  832 QSQLEAKEREVREGTerlrdiSQEMEGLSqalsqkELEiAKMDQLLLEKQKDVETLQQTIQEKDQQVTELSFSMTEKMV- 910
Cdd:pfam15921  298 QSQLEIIQEQARNQN------SMYMRQLS------DLE-STVSQLRSELREAKRMYEDKIEELEKQLVLANSELTEARTe 364

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  911 --QLNEEKFSLGVEIKTLKEQLNLLSRTEEATKEQ---VEESGAGSSLKLGH-----DESGQE--GLQQELELLRKESEQ 978
Cdd:pfam15921  365 rdQFSQESGNLDDQLQKLLADLHKREKELSLEKEQnkrLWDRDTGNSITIDHlrrelDDRNMEvqRLEALLKAMKSECQG 444

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  979 RKRKLQAALINRKELLQKVSQLEEELAKVREDSRKEIPFGENERRKLEEDRENRDDPEEWGTSKWREVEAS------LKQ 1052
Cdd:pfam15921  445 QMERQMAAIQGKNESLEKVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEATnaeitkLRS 524

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1053 TISEKEVELEGIRRDLKEKTAAEEELQAVVQRMTrdlqSKTKQIDLLQEEVtENQATIQKLVTGTMDAGNGGSAAPVKET 1132
Cdd:pfam15921  525 RVDLKLQELQHLKNEGDHLRNVQTECEALKLQMA----EKDKVIEILRQQI-ENMTQLVGQHGRTAGAMQVEKAQLEKEI 599

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1133 ------AASSPPGAGGEEHWKPELEGRILDLEKDKTQLQKKLQEALIARKAIlkkAQEKEKQLKE------ELREQKDAY 1200
Cdd:pfam15921  600 ndrrleLQEFKILKDKKDAKIRELEARVSDLELEKVKLVNAGSERLRAVKDI---KQERDQLLNEvktsrnELNSLSEDY 676

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1201 HHLQGQFHEQNKEKENIADQLRqLQCQARESIDRQLPGTGQQEPGPPAPSLE-GISLEDTEPASESDLHAAQpsppGETA 1279
Cdd:pfam15921  677 EVLKRNFRNKSEEMETTTNKLK-MQLKSAQSELEQTRNTLKSMEGSDGHAMKvAMGMQKQITAKRGQIDALQ----SKIQ 751

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1280 ALQATVSVAqiQAQLKEMEVEKEELELKVSSIASELAKKSEEVLLLQDQINEQGLEIQNL-----KAASVEAQAHTELLK 1354
Cdd:pfam15921  752 FLEEAMTNA--NKEKHFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANMevaldKASLQFAECQDIIQR 829

                          650       660
                   ....*....|....*....|
gi 1720386946 1355 QELESSQLKVAGLEHLKTLQ 1374
Cdd:pfam15921  830 QEQESVRLKLQHTLDVKELQ 849
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
832-1071 1.50e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 44.52  E-value: 1.50e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  832 QSQLEAKEREVREGTERLRDISQEMEGLSQALS--QKELEIAKMDQLLLEKQKDVETLQQTIQEKDQQVTELSFSMtekm 909
Cdd:COG4913    609 RAKLAALEAELAELEEELAEAEERLEALEAELDalQERREALQRLAEYSWDEIDVASAEREIAELEAELERLDASS---- 684

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  910 vqlneekfslgVEIKTLKEQLnllsrteeatkeqveesgagsslklghdesgqEGLQQELELLRKESEQRKRKLQAALIN 989
Cdd:COG4913    685 -----------DDLAALEEQL--------------------------------EELEAELEELEEELDELKGEIGRLEKE 721

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  990 RKELLQKVSQLEEELAKVREDSRKEIPFGENERRKLEEDRENRDDPEEWgtskWREVEASLKQTISEKEVELEGIRRDLK 1069
Cdd:COG4913    722 LEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGDAVERELREN----LEERIDALRARLNRAEEELERAMRAFN 797


                   ..
gi 1720386946 1070 EK 1071
Cdd:COG4913    798 RE 799
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
2706-2877 1.70e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 44.14  E-value: 1.70e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2706 AQIQAFGRSMSSLQDSRDHATEELGDLKKKYDASLKELAQLKEWQDSSREGDVLSQAAFPLSTSENVLSRLEKLNQQLTS 2785
Cdd:COG4913    610 AKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEIDVASAEREIAELEAELERLDASSDDLAA 689

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2786 KDEQLLHLSSELESSHNQVQSISKAMTSLQNERDRLWSELEKFRKSEEGKQRAAAPSAASSPAEV-------QSLKKAMS 2858
Cdd:COG4913    690 LEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERfaaalgdAVERELRE 769

                          170
                   ....*....|....*....
gi 1720386946 2859 SLQNDRDRLLKELKNLQQQ 2877
Cdd:COG4913    770 NLEERIDALRARLNRAEEE 788
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1947-2330 1.71e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 43.99  E-value: 1.71e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1947 VSELEEEKQQLVKEKTKVESEIRKEYMEKIQGAQKGPANKSHAKELQELLREKQQEVKQLQKDCIRYLERISALEKTVKA 2026
Cdd:COG4717     48 LERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQL 127

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2027 LEfvhtesqkdldvtkgnlaqAVEHRKKAQAELSSFKILLDDTQSEAARVladnlklkKELQSNKESIKSQIKQKDEDLL 2106
Cdd:COG4717    128 LP-------------------LYQELEALEAELAELPERLEELEERLEEL--------RELEEELEELEAELAELQEELE 180

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2107 RRLEQAEEKHRKEKKNMQEKLDALHREKAHVEETLAEIQVSLTRKDQEMKELQGSLDS---------------------- 2164
Cdd:COG4717    181 ELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAaaleerlkearlllliaaalla 260

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2165 -------------------------TLAQLAAFTKSMSSLQDDRDRVIDEA----------KKWERRFGDAIQTKEEEVR 2209
Cdd:COG4717    261 llglggsllsliltiagvlflvlglLALLFLLLAREKASLGKEAEELQALPaleeleeeelEELLAALGLPPDLSPEELL 340

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2210 LKEENCIALKDQLRQMAIHMEELKITVSRLEHDKEIWESKAQTE-----LQHHQKAYDKLQEENKELTSQLEDARQLYHD 2284
Cdd:COG4717    341 ELLDRIEELQELLREAEELEEELQLEELEQEIAALLAEAGVEDEeelraALEQAEEYQELKEELEELEEQLEELLGELEE 420

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|....*...
gi 1720386946 2285 SKNELTK--LESELKSLKDQTTDLNNSLEKCKEHENNLEGIIKQQEAD 2330
Cdd:COG4717    421 LLEALDEeeLEEELEELEEELEELEEELEELREELAELEAELEQLEED 468
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
156-359 1.83e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 43.85  E-value: 1.83e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  156 QEKEKLISSLQAQLDQSEQasQLDKSSAEMEDF------VLMKQQLQEKEELISTLQTQLSQTQAEQAAqvVREKDARFE 229
Cdd:COG3206    171 EEARKALEFLEEQLPELRK--ELEEAEAALEEFrqknglVDLSEEAKLLLQQLSELESQLAEARAELAE--AEARLAALR 246

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  230 TQVRLHEDELLQLVTQSDVET------EMQQKLRVMQRKL-EEHEEALLGRAQVVDLLQKELTSAEQRNQVLSQQLQLLE 302
Cdd:COG3206    247 AQLGSGPDALPELLQSPVIQQlraqlaELEAELAELSARYtPNHPDVIALRAQIAALRAQLQQEAQRILASLEAELEALQ 326

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 1720386946  303 AEHNTLKNTMETERQESKTLMEK-VELEVAERKLSfhNLQEEMHQLQGQLERAGQAQA 359
Cdd:COG3206    327 AREASLQAQLAQLEARLAELPELeAELRRLEREVE--VARELYESLLQRLEEARLAEA 382
PLN03229 PLN03229
acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional
 678-1031 1.97e-03

acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Provisional


Pssm-ID: 178768 [Multi-domain]  Cd Length: 762  Bit Score: 44.07  E-value: 1.97e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  678 QGELERLKTQVLELETSLHTAEETYKRNLSEKVKEISSLtQLSEEVKESAEEARstLAAVTEE------RDQLLYQVkel 751
Cdd:PLN03229   435 EGEVEKLKEQILKAKESSSKPSELALNEMIEKLKKEIDL-EYTEAVIAMGLQER--LENLREEfskansQDQLMHPV--- 508

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  752 dvLAELRARV-QELESSLAEAEkqrglDYESQRAQHNLLTEqiHSLSIEAKSKDVKIEALQRELDgvqlQFCEQGTQMKT 830
Cdd:PLN03229   509 --LMEKIEKLkDEFNKRLSRAP-----NYLSLKYKLDMLNE--FSRAKALSEKKSKAEKLKAEIN----KKFKEVMDRPE 575

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  831 LQSQLEA-KEREVREGTERLRDISQEM-EGLSQALSQKELEIAK----MD-QLLLEKQKDVETLQQTIQEkdqqvtelsf 903
Cdd:PLN03229   576 IKEKMEAlKAEVASSGASSGDELDDDLkEKVEKMKKEIELELAGvlksMGlEVIGVTKKNKDTAEQTPPP---------- 645

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  904 SMTEKMVQLNEEkfsLGVEIKTLKEQLNLLSRTEEatkeqveesgagssLKLGHDESGQEGLQQELELLRKESEQRKRKL 983
Cdd:PLN03229   646 NLQEKIESLNEE---INKKIERVIRSSDLKSKIEL--------------LKLEVAKASKTPDVTEKEKIEALEQQIKQKI 708

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*...
gi 1720386946  984 QAALiNRKELLQKVSQLEEELAKVREDSRkeipfGENERRKLEEDREN 1031
Cdd:PLN03229   709 AEAL-NSSELKEKFEELEAELAAARETAA-----ESNGSLKNDDDKEE 750
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
2528-2966 2.00e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 43.99  E-value: 2.00e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2528 IKDSQQKQLLDAQLQQNKELRNECTKLEERLKGLEAEKQSLQMSSDALQKEKQGLSKEIKNLQTQLTALQEEGTLGVYHA 2607
Cdd:COG4717     67 ELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQELEALEAELAELPE 146

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2608 Q---LKAKEEELQRLNMALSSSQKRTADLEEELVCVQKEATRKVSEIEDQLKKELKHLHHDAGIMRNETETAEERVAELA 2684
Cdd:COG4717    147 RleeLEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELE 226

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2685 RDLVEMEQKLLTVTKENKDLMAQIQAFGRSMSSLQDSRDHATEELGDLKKKYDASLKELAQL-------KEWQDSSREGD 2757
Cdd:COG4717    227 EELEQLENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALlflllarEKASLGKEAEE 306

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2758 VLSQAAFPLSTSENVLSRLEKLNQQLTSKDEQLLHLSSELESSHNQVQSISKAMTSLQneRDRLWSELEKFRKSEEGKQR 2837
Cdd:COG4717    307 LQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQ--LEELEQEIAALLAEAGVEDE 384

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2838 AAAPSAASSPAEVQSLKKAMSSLQNDRDRLLKELKNLqqqylqmsQEMTELRPLKAQLQESQDQTKALQVMEEELRQENL 2917
Cdd:COG4717    385 EELRAALEQAEEYQELKEELEELEEQLEELLGELEEL--------LEALDEEELEEELEELEEELEELEEELEELREELA 456

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2918 SWQHELRQLRMEKNSWEL-HERRMKEQFLMAISDKDQQLGHLQSLLRELR 2966
Cdd:COG4717    457 ELEAELEQLEEDGELAELlQELEELKAELRELAEEWAALKLALELLEEAR 506
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1041-1293 2.07e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 43.28  E-value: 2.07e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1041 SKWREVEASLKQTISEKEVELEGIRRDLKEKTAAEEELQAVVQRMTRDLQSKTKQIDLLQEEVTENQATIQKLVTGTMDA 1120
Cdd:COG3883     19 QAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARALYRS 98

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1121 GNGGSAAPVKETAASSppgagGEEHWKPELEGRILDLEKDKTQLQKKLQEALIARKAILKKAQEKEKQLKEELREQKDAy 1200
Cdd:COG3883     99 GGSVSYLDVLLGSESF-----SDFLDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAE- 172

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1201 hhLQGQFHEQNKEKENIADQLRQLQcQARESIDRQLPGTGQQEPGPPAPSLEGISLEDTEPASESDLHAAQPSPPGETAA 1280
Cdd:COG3883    173 --LEAQQAEQEALLAQLSAEEAAAE-AQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAASAAGA 249

                          250
                   ....*....|...
gi 1720386946 1281 LQATVSVAQIQAQ 1293
Cdd:COG3883    250 GAAGAAGAAAGSA 262
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 1830-2425 2.15e-03

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 43.94  E-value: 2.15e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1830 RIAELEMEKQKDRELSQALENEKNALLTQISakdsELKLLEEevTKRTTLNQQIQEELCRVTKLKETAEEEKDDLEER-- 1907
Cdd:pfam05483  170 KTKKYEYEREETRQVYMDLNNNIEKMILAFE----ELRVQAE--NARLEMHFKLKEDHEKIQHLEEEYKKEINDKEKQvs 243

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1908 -LMNQLAELNGSIGNYYQDVTDAQIKNEQLESEMRNLQRCVSELEEEKQQLVKEKTKVeseirKEYMEKIQGAQKGPANK 1986
Cdd:pfam05483  244 lLLIQITEKENKMKDLTFLLEESRDKANQLEEKTKLQDENLKELIEKKDHLTKELEDI-----KMSLQRSMSTQKALEED 318

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1987 SH--AKELQELLREKQQEVKQLQKDCIRYLERISALEKTVKALEFVHTESQKDLDVTKGNLAQAVEHRKKAQAELSSFKI 2064
Cdd:pfam05483  319 LQiaTKTICQLTEEKEAQMEELNKAKAAHSFVVTEFEATTCSLEELLRTEQQRLEKNEDQLKIITMELQKKSSELEEMTK 398

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2065 LLDDTQ---SEAARVLADNLKLKKElQSNKESIKSQIKQKDEDLLRRLEQAEekhrKEKKNMQEKLDALHREKAHVEETL 2141
Cdd:pfam05483  399 FKNNKEvelEELKKILAEDEKLLDE-KKQFEKIAEELKGKEQELIFLLQARE----KEIHDLEIQLTAIKTSEEHYLKEV 473

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2142 AEIQVSLTRKDQEMKELQGSLDSTLAQLAAFTKSMS----SLQDDRDRVIDEAKKWERRFGDAIQTKEEEVRLKEE---- 2213
Cdd:pfam05483  474 EDLKTELEKEKLKNIELTAHCDKLLLENKELTQEASdmtlELKKHQEDIINCKKQEERMLKQIENLEEKEMNLRDElesv 553

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2214 ------NCIALKDQLRQMAIHMEELKITVSRLEHDKEIWESKA---QTELQHHQKAYDKLQEENKELTSQLEDARQLYHD 2284
Cdd:pfam05483  554 reefiqKGDEVKCKLDKSEENARSIEYEVLKKEKQMKILENKCnnlKKQIENKNKNIEELHQENKALKKKGSAENKQLNA 633

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2285 SKNELTKLESELKSLKDQTTDLNNSLEKCKE----HENNLEGIIKQQEADI-------QNCKFSCEQLETDLAASRELTS 2353
Cdd:pfam05483  634 YEIKVNKLELELASAKQKFEEIIDNYQKEIEdkkiSEEKLLEEVEKAKAIAdeavklqKEIDKRCQHKIAEMVALMEKHK 713

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1720386946 2354 RLHDEINAKEQKIISLLSGKEEAIQLAVEELHQQHSKEIKELENLLSQEEEENVALEEENKRALEKTNQLTE 2425
Cdd:pfam05483  714 HQYDKIIEERDSELGLYKNKEQEQSSAKAALEIELSNIKAELLSLKKQLEIEKEEKEKLKMEAKENTAILKD 785
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 184-439 2.16e-03

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 43.96  E-value: 2.16e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  184 EMEDFVLMKQQL--QEKEELISTLQTQLSQTQAEQAAQVVREKDARF---ETQVRLHEDELLQLVTQSDVETEM----QQ 254
Cdd:pfam17380  289 QQEKFEKMEQERlrQEKEEKAREVERRRKLEEAEKARQAEMDRQAAIyaeQERMAMERERELERIRQEERKRELerirQE 368

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  255 KLRVMQRKLEEHEEALLGRAQVVDLLQKELTSA-------EQRNQVLSQQLQLLEAEHNTLKNTMETERQ----ESKTLM 323
Cdd:pfam17380  369 EIAMEISRMRELERLQMERQQKNERVRQELEAArkvkileEERQRKIQQQKVEMEQIRAEQEEARQREVRrleeERAREM 448

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  324 EKVELEVAERKLSFHNL---QEEMHQLQGQLERAGQAQADLETQYSALQQRhktEMEEKTACILSLQKN----EQELQSA 396
Cdd:pfam17380  449 ERVRLEEQERQQQVERLrqqEEERKRKKLELEKEKRDRKRAEEQRRKILEK---ELEERKQAMIEEERKrkllEKEMEER 525

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|...
gi 1720386946  397 CAALKEENSKLLQEKHDQAAESAQAMRQLEDQLQQKSKEISQF 439
Cdd:pfam17380  526 QKAIYEEERRREAEEERRKQQEMEERRRIQEQMRKATEERSRL 568
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2265-2487 2.19e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.21  E-value: 2.19e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2265 QEENKELTSQLEDARQLYHDSKNELTKLESELKSLKDQTTDLNNSLEKCKEHENNLEGIIKQQEADIQNCKFSCEQLETD 2344
Cdd:COG4942     19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE 98

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2345 LAASRELTSRLHDEI-NAKEQKIISLLSGKEEAIQLA-----VEELHQQHSKEIKELENLLSQEEEENVALEEENKRALE 2418
Cdd:COG4942     99 LEAQKEELAELLRALyRLGRQPPLALLLSPEDFLDAVrrlqyLKYLAPARREQAEELRADLAELAALRAELEAERAELEA 178

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1720386946 2419 KTNQLTEALEAIKKESFEQKAQLDSFVKSMSSLQDDRDRIVSDYRQLEERHLSAILEKDQLIQDAAAEN 2487
Cdd:COG4942    179 LLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAG 247
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 2189-2860 2.25e-03

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 44.06  E-value: 2.25e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2189 EAKKWERRFGdaiQTKEEEVRLKEENcIALKDQLRQMAIHMEELKITVSRLEH-----DKEIWESKAqtELQHHQKAYDK 2263
Cdd:pfam12128  242 EFTKLQQEFN---TLESAELRLSHLH-FGYKSDETLIASRQEERQETSAELNQllrtlDDQWKEKRD--ELNGELSAADA 315

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2264 LQEENKELTSQLEDARQLYHDSKNELTKLESE-LKSLKDQTTDLNNSLEKCKEHENNLEGIIKQQEADI-QNCKFSCEQL 2341
Cdd:pfam12128  316 AVAKDRSELEALEDQHGAFLDADIETAAADQEqLPSWQSELENLEERLKALTGKHQDVTAKYNRRRSKIkEQNNRDIAGI 395

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2342 ETDLAASRELTSRLHDEINAKEQKIISLLSGKEEAIQLAVEELHQQHSKEIKELENLLSQEEEENVAleeenkraLEKTN 2421
Cdd:pfam12128  396 KDKLAKIREARDRQLAVAEDDLQALESELREQLEAGKLEFNEEEYRLKSRLGELKLRLNQATATPEL--------LLQLE 467

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2422 QLTEALEAIKKESFEQKAQLDSFVKSMSSLQDDRDRIVSDYRQLEERHLSAILEKDQLIQDAAAENNKLKEEmrgLRSHM 2501
Cdd:pfam12128  468 NFDERIERAREEQEAANAEVERLQSELRQARKRRDQASEALRQASRRLEERQSALDELELQLFPQAGTLLHF---LRKEA 544

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2502 DDLNSENAKLDAELVQYRRDLN-EVIAIKDSQQKQL----LDAQLQQNKELRNECTKLEERLKGLEAEKQSLQMSSDALQ 2576
Cdd:pfam12128  545 PDWEQSIGKVISPELLHRTDLDpEVWDGSVGGELNLygvkLDLKRIDVPEWAASEEELRERLDKAEEALQSAREKQAAAE 624

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2577 KEKQGLSKEIKNLQTQLTALQeegtlgvyhAQLKAKEEELQRLNMALSSSQKRtadLEEELVCVQKEATRKVSEIEDQlK 2656
Cdd:pfam12128  625 EQLVQANGELEKASREETFAR---------TALKNARLDLRRLFDEKQSEKDK---KNKALAERKDSANERLNSLEAQ-L 691

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2657 KELKHLHHDAgimrnetetAEERVAELARDLVEMEQKLLTVTKENKDLMAQIQAfgrsmsSLQDSRDHATEELGDLKKKY 2736
Cdd:pfam12128  692 KQLDKKHQAW---------LEEQKEQKREARTEKQAYWQVVEGALDAQLALLKA------AIAARRSGAKAELKALETWY 756

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2737 DASLKELAQlkewqdssrEGDVLSQAAFPLSTSENVLSRLEKLNQQLTSKDEQLLH-LSSELESSHNQVQSISKAMTSLQ 2815
Cdd:pfam12128  757 KRDLASLGV---------DPDVIAKLKREIRTLERKIERIAVRRQEVLRYFDWYQEtWLQRRPRLATQLSNIERAISELQ 827

                          650       660       670       680
                   ....*....|....*....|....*....|....*....|....*
gi 1720386946 2816 NERDRLWSELEKFRKSEEGKQRAAAPSAASSPAEVQSLKKAMSSL 2860
Cdd:pfam12128  828 QQLARLIADTKLRRAKLEMERKASEKQQVRLSENLRGLRCEMSKL 872
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1311-2069 2.26e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 43.90  E-value: 2.26e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1311 IASELAKKSEEVLLLQDQINEQGLEI----QNLKAASVEAQAHTE----LLKQELESSQLKVAGLEH-LKTLQPELDALH 1381
Cdd:TIGR02169  242 IERQLASLEEELEKLTEEISELEKRLeeieQLLEELNKKIKDLGEeeqlRVKEKIGELEAEIASLERsIAEKERELEDAE 321

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1382 KHMGQKEEEVNYLYGQLSEKEQTLTTVQTEMVEQERLIKALHTQLEMQAKEHEERLKQAQVEICELKKKPTELEEETNAK 1461
Cdd:TIGR02169  322 ERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREI 401

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1462 QQLQRklqaalisrkealkENKSLQEQLSSARDAVERLTKSLADVEsqvsvqnqekdavlGKLTILQEERDKLIAEMDRF 1541
Cdd:TIGR02169  402 NELKR--------------ELDRLQEELQRLSEELADLNAAIAGIE--------------AKINELEEEKEDKALEIKKQ 453

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1542 LLENQSLSGSCESLKLALGGLTEDKEKLMEELESVRSskmaestEWQEKHKELQKEYEVLLQSYENVSNEAERIQHVVES 1621
Cdd:TIGR02169  454 EWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQR-------ELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGT 526

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1622 VRQ--EKQELYAKLRSTESDKRerekqLQDAEQEMEEMKEKMRKFAKSKQ---------QKILELEEENDRLR------- 1683
Cdd:TIGR02169  527 VAQlgSVGERYATAIEVAAGNR-----LNNVVVEDDAVAKEAIELLKRRKagratflplNKMRDERRDLSILSedgvigf 601

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1684 -------------AEAQPVGGTG--ESMEA---------LLSSNSSLKEELEKITLEHKTLSKEFEALMAEKDALSEETR 1739
Cdd:TIGR02169  602 avdlvefdpkyepAFKYVFGDTLvvEDIEAarrlmgkyrMVTLEGELFEKSGAMTGGSRAPRGGILFSRSEPAELQRLRE 681

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1740 NL-KLQVEAQVLKQASLEATEKSDEPKDVIEEVTQAVVGKSQERDALSD-----SAKLEDSEAILMgdgakpgvsetfSS 1813
Cdd:TIGR02169  682 RLeGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQeeeklKERLEELEEDLS------------SL 749

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1814 HDDIKNYLQQLDQLKGRIAELEMEKQKDRELSQALENEKNAllTQISAKDSELKLLEEEVTKRTTLNQQIQEELCRVTKL 1893
Cdd:TIGR02169  750 EQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSH--SRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLE 827

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1894 KETAEEEKDDLEErlmnQLAELNGSIGNYYQDVTDAQIKNEQLESEMRNLQRCVSELEEEKQQLVKEKTKVESEIRKEYM 1973
Cdd:TIGR02169  828 KEYLEKEIQELQE----QRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELER 903

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1974 EKIQGAQKGPANKSHAKELQELLREKQQEVKQLQKDCIRYLE-------------RISALEKTVKALEFVHTESQKDLDV 2040
Cdd:TIGR02169  904 KIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEipeeelsledvqaELQRVEEEIRALEPVNMLAIQEYEE 983

                          810       820
                   ....*....|....*....|....*....
gi 1720386946 2041 TKGNLAQAVEHRKKAQAELSSFKILLDDT 2069
Cdd:TIGR02169  984 VLKRLDELKEKRAKLEEERKAILERIEEY 1012
PTZ00121 PTZ00121
MAEBL; Provisional
 1312-1771 2.43e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 43.98  E-value: 2.43e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1312 ASELAKKSEEVLLLQDQINEQGLEIqnlKAASVEAQAHTELLKQELESSQLKVAGLEHLKTLQPELDALHKHMGQKEEEV 1391
Cdd:PTZ00121  1317 ADEAKKKAEEAKKKADAAKKKAEEA---KKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKA 1393

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1392 NYLYGQLSEKEQTLTTVQTEMVEQERLIKALHTQLEMQAKEHEERLKQAQVEICELKKKPTELEEETNAKQQLQRKLQAA 1471
Cdd:PTZ00121  1394 DEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKAD 1473

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1472 LISRK-EALKENKSLQEQLSSARDAVERLTKSLADVESQVSVQNQEKDAVLGKLTILQEERdkliaemdrfllenqslsg 1550
Cdd:PTZ00121  1474 EAKKKaEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAK------------------- 1534

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1551 SCESLKLALGGLTEDKEKLMEELESVRSSKMAEstewqEKHKELQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQELY 1630
Cdd:PTZ00121  1535 KADEAKKAEEKKKADELKKAEELKKAEEKKKAE-----EAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKA 1609

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1631 AKLRSTESDKREREKQLQDAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEAQPVGGTGESMEAllssNSSLKEEL 1710
Cdd:PTZ00121  1610 EEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKA----EEAKKAEE 1685

                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1720386946 1711 EKITLEHKTLSKEFEALMAE---KDALSEETRNLKLQVEAQVLKQASLEATEKSDEPKDVIEEV 1771
Cdd:PTZ00121  1686 DEKKAAEALKKEAEEAKKAEelkKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEA 1749
ClpA COG0542
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ...
 2553-2652 2.68e-03

ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440308 [Multi-domain]  Cd Length: 836  Bit Score: 43.53  E-value: 2.68e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2553 KLEERLKGLEAEKQSLQMSSDALQKEK-QGLSKEIKNLQTQLTAL----QEEGTLgvyHAQLKAKEEELQRLNMALSSSQ 2627
Cdd:COG0542    415 ELERRLEQLEIEKEALKKEQDEASFERlAELRDELAELEEELEALkarwEAEKEL---IEEIQELKEELEQRYGKIPELE 491

                           90       100
                   ....*....|....*....|....*
gi 1720386946 2628 KRTADLEEELVCVQKEATRKVSEIE 2652
Cdd:COG0542    492 KELAELEEELAELAPLLREEVTEED 516
PTZ00121 PTZ00121
MAEBL; Provisional
 2067-2790 2.69e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 43.59  E-value: 2.69e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2067 DDTQSEAARVLADNLKLKKELQSNKESIKSQIKQKDEDLlRRLEQ---AEEKHRKEKKNMQEklDALHREKAHVEETLAE 2143
Cdd:PTZ00121  1089 ADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDA-RKAEEarkAEDARKAEEARKAE--DAKRVEIARKAEDARK 1165

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2144 IQVSltRKDQEMKELQGsldstlAQLAAFTKSMSSLQDDRD-RVIDEAKKWERrfgdaIQTKEEEVRLKEENCIALKDQL 2222
Cdd:PTZ00121  1166 AEEA--RKAEDAKKAEA------ARKAEEVRKAEELRKAEDaRKAEAARKAEE-----ERKAEEARKAEDAKKAEAVKKA 1232

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2223 RQMAIHMEELKITVSRLEHDKEIWESKAQTELQHHQKAYDKLQEENK-ELTSQLEDARQLYHDSKNELTKLESELKSLKD 2301
Cdd:PTZ00121  1233 EEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKaDELKKAEEKKKADEAKKAEEKKKADEAKKKAE 1312

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2302 QTTDLNNSLEKCKEHENNLEGIIKQQEadiqnckfscEQLETDLAASRELTSRlHDEINAKEQKIISLLSGKEEAIQLAv 2381
Cdd:PTZ00121  1313 EAKKADEAKKKAEEAKKKADAAKKKAE----------EAKKAAEAAKAEAEAA-ADEAEAAEEKAEAAEKKKEEAKKKA- 1380

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2382 eELHQQHSKEIKELENLLSQEEEENVALEEENKRALEKtnqltEALEAIKKESFEQKAQLDSFVKSMSSLQDDRDRivsd 2461
Cdd:PTZ00121  1381 -DAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAK-----KKADEAKKKAEEKKKADEAKKKAEEAKKADEAK---- 1450

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2462 yRQLEERHLSAILEKDQLIQDAAAENNKLKEEMRglrshmddlNSENAKLDAELVQYRRDlneVIAIKDSQQKQLLDAQL 2541
Cdd:PTZ00121  1451 -KKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAK---------KADEAKKKAEEAKKKAD---EAKKAAEAKKKADEAKK 1517

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2542 QQNKELRNECTKLEERLKGLEAEKQSLQMSSDALQKEKQGLSKEIKNLQTQLTALQEEGTLGVYHAQL-----KAKEEEL 2616
Cdd:PTZ00121  1518 AEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEakkaeEARIEEV 1597

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2617 QRLNMALSSSQKRTADLEEElVCVQKEATRKVSEIE---DQLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQK 2693
Cdd:PTZ00121  1598 MKLYEEEKKMKAEEAKKAEE-AKIKAEELKKAEEEKkkvEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKK 1676

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2694 LLTVTKENKDLMAQIQAFGRSMSSLQDSRDHATEELGDLKKKYDASLKELAQLKEWQDSSREGDVLSQAAFPLSTSENVL 2773
Cdd:PTZ00121  1677 AEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEK 1756

                          730
                   ....*....|....*..
gi 1720386946 2774 SRLEKLNQQLTSKDEQL 2790
Cdd:PTZ00121  1757 KKIAHLKKEEEKKAEEI 1773
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 1415-2003 2.82e-03

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 43.56  E-value: 2.82e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1415 QERLIKALHTQLEMQAKEHEERLKQAQVEicelkkkpTELEEETNAKQqlqRKLQAALISRKEALKENKSLQEQLSSARD 1494
Cdd:pfam05483  200 EELRVQAENARLEMHFKLKEDHEKIQHLE--------EEYKKEINDKE---KQVSLLLIQITEKENKMKDLTFLLEESRD 268

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1495 AVERLtksladvESQVSVQNQEKDAVLGKLTILQEERDKLIAEMDRFLLENQSLSGSCESLKLALGGLTEDKEKLMEELE 1574
Cdd:pfam05483  269 KANQL-------EEKTKLQDENLKELIEKKDHLTKELEDIKMSLQRSMSTQKALEEDLQIATKTICQLTEEKEAQMEELN 341

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1575 SVRSSKMAESTEWQEKHKELQKEYEVLLQSYENVSNEAERIQHVVESVRQEKQELYAKLRSTESDKREREKQL---QDAE 1651
Cdd:pfam05483  342 KAKAAHSFVVTEFEATTCSLEELLRTEQQRLEKNEDQLKIITMELQKKSSELEEMTKFKNNKEVELEELKKILaedEKLL 421

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1652 QEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEAQPVGGTGESMEALLSSNSSLKEELEKITLEHKTLSKEFEALMAEK 1731
Cdd:pfam05483  422 DEKKQFEKIAEELKGKEQELIFLLQAREKEIHDLEIQLTAIKTSEEHYLKEVEDLKTELEKEKLKNIELTAHCDKLLLEN 501

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1732 DALSEETRNLKLQVEAQvlkqasleateksdePKDVIEevtqavvGKSQERDALSDSAKLEDSEAILMgDGAKPGVSETF 1811
Cdd:pfam05483  502 KELTQEASDMTLELKKH---------------QEDIIN-------CKKQEERMLKQIENLEEKEMNLR-DELESVREEFI 558

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1812 SSHDDIKNylqQLDQLKGRIAELEMEKQKDRELSQALENEKNALLTQISAKDSELKLLEEE----VTKRTTLNQQIQEEL 1887
Cdd:pfam05483  559 QKGDEVKC---KLDKSEENARSIEYEVLKKEKQMKILENKCNNLKKQIENKNKNIEELHQEnkalKKKGSAENKQLNAYE 635

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1888 CRVTKLKETAEEEKDDLEErlmnqlaelngSIGNYYQDVTDAQIKNEQLESEMrnlqrcvseleEEKQQLVKEKTKVESE 1967
Cdd:pfam05483  636 IKVNKLELELASAKQKFEE-----------IIDNYQKEIEDKKISEEKLLEEV-----------EKAKAIADEAVKLQKE 693

                          570       580       590
                   ....*....|....*....|....*....|....*.
gi 1720386946 1968 IRKEYMEKIqgAQKGPANKSHAKELQELLREKQQEV 2003
Cdd:pfam05483  694 IDKRCQHKI--AEMVALMEKHKHQYDKIIEERDSEL 727
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1993-2209 2.97e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.83  E-value: 2.97e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1993 QELLREKQQEVKQLQKdciryleRISALEKTVKALEFVHTESQKDLDVTKGNLAQAVEHRKKAQAELSSFKILLDDTQSE 2072
Cdd:COG4942     19 ADAAAEAEAELEQLQQ-------EIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKE 91

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2073 AARVLADNLKLKKELqsnKESIKSQIKQKDEDLLRRLEQAEEKHRKEKknMQEKLDALHREKAHVEETLAEIQVSLTRKD 2152
Cdd:COG4942     92 IAELRAELEAQKEEL---AELLRALYRLGRQPPLALLLSPEDFLDAVR--RLQYLKYLAPARREQAEELRADLAELAALR 166

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1720386946 2153 QEMKELQGSLDSTLAQLAAFTKSMSSLQDDRDRVIDEAKKWERRFGDAIQTKEEEVR 2209
Cdd:COG4942    167 AELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAE 223
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
2545-3030 2.98e-03

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 43.51  E-value: 2.98e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2545 KELRNECTKLEERLKGLEAEKQSLQMSSDALQKEKQGLSKEIKNLQTQLTALQEE-GTLGVYHAQLKAKEEELQRLNMAL 2623
Cdd:PRK03918   168 GEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREElEKLEKEVKELEELKEEIEELEKEL 247

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2624 SSSQKRTADLEEELVCVQKEATRKVSEIEDqLKKELKHLhhdagimrNETETAEERVAELARDLVEMEQKLLTVTKENKD 2703
Cdd:PRK03918   248 ESLEGSKRKLEEKIRELEERIEELKKEIEE-LEEKVKEL--------KELKEKAEEYIKLSEFYEEYLDELREIEKRLSR 318

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2704 LMAQIQAFGRSMSSLQDSRdhatEELGDLKKKYDASLKELAQLKEWQDSSREGDVLSQAAFPLSTSENVLSrLEKLNQQL 2783
Cdd:PRK03918   319 LEEEINGIEERIKELEEKE----ERLEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLT-PEKLEKEL 393

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2784 TSKDEQLLHLSSELESshnqvqsISKAMTSLQNERDRLWSELEKFRKSE--------EGKQRAAAPSAASSPAEVQSLKK 2855
Cdd:PRK03918   394 EELEKAKEEIEEEISK-------ITARIGELKKEIKELKKAIEELKKAKgkcpvcgrELTEEHRKELLEEYTAELKRIEK 466

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2856 AMSSLQNDRDRLLKELKNLQQQyLQMSQEMTELRPLKAQLQESQDQTKALQVME--------EELRQENLSWQHELRQLR 2927
Cdd:PRK03918   467 ELKEIEEKERKLRKELRELEKV-LKKESELIKLKELAEQLKELEEKLKKYNLEElekkaeeyEKLKEKLIKLKGEIKSLK 545

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2928 MEKNSWELHERRmKEQFLMAISDKDQQLGHLQSLLRELRSSSQAQI------LSTQYQR-----QASPETSASLDGSQKL 2996
Cdd:PRK03918   546 KELEKLEELKKK-LAELEKKLDELEEELAELLKELEELGFESVEELeerlkeLEPFYNEylelkDAEKELEREEKELKKL 624

                          490       500       510
                   ....*....|....*....|....*....|....
gi 1720386946 2997 VYETELLRTQLNDSLKEIHQKELRIQQLNSKFSQ 3030
Cdd:PRK03918   625 EEELDKAFEELAETEKRLEELRKELEELEKKYSE 658
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 879-1130 3.59e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.83  E-value: 3.59e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  879 EKQKDVETLQQTIQEKDQQVTelsfsmtekmvQLNEEKFSLGVEIKTLKEQLNLLSRTEEATKEQVEESGAgsslKLGHD 958
Cdd:COG4942     24 EAEAELEQLQQEIAELEKELA-----------ALKKEEKALLKQLAALERRIAALARRIRALEQELAALEA----ELAEL 88

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  959 ESGQEGLQQELELLRKESEQRKRKLQAALINRKELLQKVSQLEEELAKVREDSRKEIPFGENERRKLEEDREnrddpeew 1038
Cdd:COG4942     89 EKEIAELRAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLA-------- 160

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1039 gtsKWREVEASLKQTISEKEVELEGIRRDLKEKTAAEEELQAVVQRMTRDLQSKTKQIDLLQEEVTENQATIQKLVTGTM 1118
Cdd:COG4942    161 ---ELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAA 237

                          250
                   ....*....|..
gi 1720386946 1119 DAGNGGSAAPVK 1130
Cdd:COG4942    238 AAAERTPAAGFA 249
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 2185-2916 3.85e-03

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 43.11  E-value: 3.85e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2185 RVIDEAKKWERRFGDAIQTKEEEVRLKE---ENCIALKDQLRQMAIHMEELKITVSRLEHD--------KEIWESKAQT- 2252
Cdd:TIGR00606  186 KALETLRQVRQTQGQKVQEHQMELKYLKqykEKACEIRDQITSKEAQLESSREIVKSYENEldplknrlKEIEHNLSKIm 265

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2253 ELQHHQKAYDKLQEENKELTSQLEDAR-QLYHDSKNELTKLE----SELKSLKDQTTDLNNSLEKckeheNNLEGIIKQQ 2327
Cdd:TIGR00606  266 KLDNEIKALKSRKKQMEKDNSELELKMeKVFQGTDEQLNDLYhnhqRTVREKERELVDCQRELEK-----LNKERRLLNQ 340

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2328 EADIQNCKFSCEQLETDLAASRELTSRLHDEINAKEQKIISLLSGKEEAIQL--AVEELHQQHSKEIKELENLLSQEEEE 2405
Cdd:TIGR00606  341 EKTELLVEQGRLQLQADRHQEHIRARDSLIQSLATRLELDGFERGPFSERQIknFHTLVIERQEDEAKTAAQLCADLQSK 420

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2406 NVALEEENKRALEKTNQLTEALEAIKKESFEQKAQLDSFVKSMSSLQDDRDRIVSDYRQL--EERHLSaILEKDQLIQDA 2483
Cdd:TIGR00606  421 ERLKQEQADEIRDEKKGLGRTIELKKEILEKKQEELKFVIKELQQLEGSSDRILELDQELrkAERELS-KAEKNSLTETL 499

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2484 AAENNKLKEEMRGLRSHMDDLNSENAKLDAE---------LVQYRRDLNEVIAIKDSQQKQLLDAQL---QQNKELRNEC 2551
Cdd:TIGR00606  500 KKEVKSLQNEKADLDRKLRKLDQEMEQLNHHtttrtqmemLTKDKMDKDEQIRKIKSRHSDELTSLLgyfPNKKQLEDWL 579

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2552 TKLEERLKGLEAEKQSLQMSSDALQKEKQGLSKEIKNLQTQLTALqEEGTLGVYHAQlkAKEEELQRLNMALSSSQKRTA 2631
Cdd:TIGR00606  580 HSKSKEINQTRDRLAKLNKELASLEQNKNHINNELESKEEQLSSY-EDKLFDVCGSQ--DEESDLERLKEEIEKSSKQRA 656

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2632 DLEEElvcvqkeatrkvSEIEDQLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLTVTKENKDLMAQIQAF 2711
Cdd:TIGR00606  657 MLAGA------------TAVYSQFITQLTDENQSCCPVCQRVFQTEAELQEFISDLQSKLRLAPDKLKSTESELKKKEKR 724

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2712 GRSMSSLQDSR----DHATEELGDLKKKYDASLKELAQLKewQDSSREGDVLSQAAFPLSTSENVLSR---LEKLNQQLT 2784
Cdd:TIGR00606  725 RDEMLGLAPGRqsiiDLKEKEIPELRNKLQKVNRDIQRLK--NDIEEQETLLGTIMPEEESAKVCLTDvtiMERFQMELK 802

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2785 SKDEQLLHLSSELESS--HNQVQSISKAMTSLQNERDRLWSELEKFRKSEEGKQRaaapsaasspaEVQSLKKAMSSLQN 2862
Cdd:TIGR00606  803 DVERKIAQQAAKLQGSdlDRTVQQVNQEKQEKQHELDTVVSKIELNRKLIQDQQE-----------QIQHLKSKTNELKS 871

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1720386946 2863 DRDRLLKELKNLQQQYLQMSQEMTELRPLKAQLQESQDQTKALQVMEEELRQEN 2916
Cdd:TIGR00606  872 EKLQIGTNLQRRQQFEEQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEK 925
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 2204-2748 3.86e-03

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 43.24  E-value: 3.86e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2204 KEEEVRLKEENCIALKDQLRQMAIHMEELKITVSRLEHDKEIWESKAQTELQhhqkaydkLQEENKELTSQLEDARQLYH 2283
Cdd:pfam01576    3 QEEEMQAKEEELQKVKERQQKAESELKELEKKHQQLCEEKNALQEQLQAETE--------LCAEAEEMRARLAARKQELE 74

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2284 DSkneLTKLESELKSLKDQTTDLNNSLEKCKEHENNLEGIIKQQEADIQ-------NCKFSCEQLETDLAASRELTSRLH 2356
Cdd:pfam01576   75 EI---LHELESRLEEEEERSQQLQNEKKKMQQHIQDLEEQLDEEEAARQklqlekvTTEAKIKKLEEDILLLEDQNSKLS 151

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2357 DEINAKEQKIISLLS--GKEEAIQLAVEELHQQHSKEIKELENLLSQEEEENVALEEENKRALEKTNQLTEALEAIKKES 2434
Cdd:pfam01576  152 KERKLLEERISEFTSnlAEEEEKAKSLSKLKNKHEAMISDLEERLKKEEKGRQELEKAKRKLEGESTDLQEQIAELQAQI 231

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2435 FEQKAQLDSFVKSMSSLQDDRDRIVSDYRQLEERHLSAILEKDQLIQDAAAE----------NNKLKEEMRGLRSHMDD- 2503
Cdd:pfam01576  232 AELRAQLAKKEEELQAALARLEEETAQKNNALKKIRELEAQISELQEDLESEraarnkaekqRRDLGEELEALKTELEDt 311

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2504 LNSENA------KLDAELVQYRRDLNEVIAIKDSQQKQLLDAQLQQNKElrnectkLEERLKGLEAEKQSLQMSSDALQK 2577
Cdd:pfam01576  312 LDTTAAqqelrsKREQEVTELKKALEEETRSHEAQLQEMRQKHTQALEE-------LTEQLEQAKRNKANLEKAKQALES 384

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2578 EKQGLSKEIKNLQTqltalqeeGTLGVYHAQLKAkEEELQRLNMALSSSQKRTADLEEELVCVQKEaTRKVSEIEDQLKK 2657
Cdd:pfam01576  385 ENAELQAELRTLQQ--------AKQDSEHKRKKL-EGQLQELQARLSESERQRAELAEKLSKLQSE-LESVSSLLNEAEG 454

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2658 ELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLTVTKENKDLMAQIQAFGRSMSSLQDSRDHATEELGDLKKKYD 2737
Cdd:pfam01576  455 KNIKLSKDVSSLESQLQDTQELLQEETRQKLNLSTRLRQLEDERNSLQEQLEEEEEAKRNVERQLSTLQAQLSDMKKKLE 534

                          570
                   ....*....|.
gi 1720386946 2738 ASLKELAQLKE 2748
Cdd:pfam01576  535 EDAGTLEALEE 545
PRK11281 PRK11281
mechanosensitive channel MscK;
69-369 3.87e-03

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 42.98  E-value: 3.87e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946   69 DIISQKDVQLQ----QKDEALQEEKKAAE----------NKIKKIKLHA---KAKIMSLNKHMEEIKTQGgAALPPEAQA 131
Cdd:PRK11281    34 DLPTEADVQAQldalNKQKLLEAEDKLVQqdleqtlallDKIDRQKEETeqlKQQLAQAPAKLRQAQAEL-EALKDDNDE 112

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  132 EELSKHNK-SSTEEEMEIEKIKHELQEKEKLISSLQAQL----DQSEQA-SQLDKSSAEMEDF-VLMKQQLQEKEELIST 204
Cdd:PRK11281   113 ETRETLSTlSLRQLESRLAQTLDQLQNAQNDLAEYNSQLvslqTQPERAqAALYANSQRLQQIrNLLKGGKVGGKALRPS 192

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  205 LQTQLsqtQAEQAAQVVREKDARFETQVRLHEDELLQLvtQSDVETEMQQKLrvmqrkleEHEEALLgraQVVdLLQKEL 284
Cdd:PRK11281   193 QRVLL---QAEQALLNAQNDLQRKSLEGNTQLQDLLQK--QRDYLTARIQRL--------EHQLQLL---QEA-INSKRL 255

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  285 TSAEQRNQVLSQQLQLLEAEHNTL-KNTMETERQESKTLMEKVELEVAerkLSFHNLQeemhqLQGQLERAGQAQADLET 363
Cdd:PRK11281   256 TLSEKTVQEAQSQDEAARIQANPLvAQELEINLQLSQRLLKATEKLNT---LTQQNLR-----VKNWLDRLTQSERNIKE 327


                   ....*.
gi 1720386946  364 QYSALQ 369
Cdd:PRK11281   328 QISVLK 333
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
2045-2683 4.19e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 42.98  E-value: 4.19e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2045 LAQAVEH---RKKAQAELSSFKILLDDTQSEAARVLADNLK-----LKKELQSNKESIkSQIKQKDEDLLRRLEQAEEKH 2116
Cdd:COG4913    254 LEPIRELaerYAAARERLAELEYLRAALRLWFAQRRLELLEaeleeLRAELARLEAEL-ERLEARLDALREELDELEAQI 332

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2117 R----KEKKNMQEKLDALHREKAHVEETLAEIQVSLTRKDQEMKELQGSLDSTLAQLAAFTKSMSSLQDDRDRVIDEAKK 2192
Cdd:COG4913    333 RgnggDRLEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEA 412

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2193 WERRFGDAIQTKEEEVR-LKE------ENCIALKDQLRqmaihmEELKITVSRL---------EHDKEIWESKAQTELqh 2256
Cdd:COG4913    413 ALRDLRRELRELEAEIAsLERrksnipARLLALRDALA------EALGLDEAELpfvgelievRPEEERWRGAIERVL-- 484

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2257 HQKAYDKLQEENkeltsQLEDARQLYHDSKNELT----KLESELKSLKDQTTDLNNSLEKCKEHENNLEGIIKQQEADIQ 2332
Cdd:COG4913    485 GGFALTLLVPPE-----HYAAALRWVNRLHLRGRlvyeRVRTGLPDPERPRLDPDSLAGKLDFKPHPFRAWLEAELGRRF 559

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2333 N--CKFSCEQLE-TDLAASRE-LTSRLHD--EINAKEQKIISLLSGKEEAIQLAVEElhqqhsKEIKELEnllsqeeeen 2406
Cdd:COG4913    560 DyvCVDSPEELRrHPRAITRAgQVKGNGTrhEKDDRRRIRSRYVLGFDNRAKLAALE------AELAELE---------- 623

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2407 valeeenkRALEKTNQLTEALEAIKKESFEQKAQLdSFVKSMSSLQDDRDRIVSDYRQLEERhLSAILEKDQLIQDAAAE 2486
Cdd:COG4913    624 --------EELAEAEERLEALEAELDALQERREAL-QRLAEYSWDEIDVASAEREIAELEAE-LERLDASSDDLAALEEQ 693

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2487 NNKLKEEMRGLRSHMDDLNSENAKLDAELVQYRRDLNEViaikdsqQKQLLDAQLQQNKELRnecTKLEERLKGLEAEKQ 2566
Cdd:COG4913    694 LEELEAELEELEEELDELKGEIGRLEKELEQAEEELDEL-------QDRLEAAEDLARLELR---ALLEERFAAALGDAV 763

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2567 SLQMsSDALQKEKQGLSKEIKNLQTQLTALQEEgtlgvYHAQLKAKEEELQRLNMALSSSQKRTADLEEElvcvqkEATR 2646
Cdd:COG4913    764 EREL-RENLEERIDALRARLNRAEEELERAMRA-----FNREWPAETADLDADLESLPEYLALLDRLEED------GLPE 831

                          650       660       670       680
                   ....*....|....*....|....*....|....*....|.
gi 1720386946 2647 KVSEIEDQLKK----ELKHLHHDagiMRNETETAEERVAEL 2683
Cdd:COG4913    832 YEERFKELLNEnsieFVADLLSK---LRRAIREIKERIDPL 869
46 PHA02562
endonuclease subunit; Provisional
 2438-2663 4.45e-03

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 42.69  E-value: 4.45e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2438 KAQLDSFVKSMSSLQDDRDRIVSDYRQLEERHLSAILEKDQLIQDAAAENNKLKEEMRGLRSHMDDLNSENAKLDAELVQ 2517
Cdd:PHA02562   194 QQQIKTYNKNIEEQRKKNGENIARKQNKYDELVEEAKTIKAEIEELTDELLNLVMDIEDPSAALNKLNTAAAKIKSKIEQ 273

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2518 YRRDlneviaIKDSQQKQLLDAQLQQNKELRNECTKLEERLKGLEaekQSLQMSSDALQKEKQ------GLSKEIKNLQT 2591
Cdd:PHA02562   274 FQKV------IKMYEKGGVCPTCTQQISEGPDRITKIKDKLKELQ---HSLEKLDTAIDELEEimdefnEQSKKLLELKN 344

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1720386946 2592 QLTalQEEGTLGVYHAQLKAKEEELQRLnmalsssQKRTADLEEELVCVQKEATRKVSEIEDqLKKELKHLH 2663
Cdd:PHA02562   345 KIS--TNKQSLITLVDKAKKVKAAIEEL-------QAEFVDNAEELAKLQDELDKIVKTKSE-LVKEKYHRG 406
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1996-2209 4.62e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 42.12  E-value: 4.62e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1996 LREKQQEVKQLQKDCIRYLERISALEKTVKALEFVHTESQKDLDVTKGNLAQAVEHRKKAQAELSSFKILLDDTQSEAAR 2075
Cdd:COG3883     18 IQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARALYR 97

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2076 VLADNLKLKKELQS-------NKESIKSQIKQKDEDLLRRLEQAEEKHRKEKKNMQEKLDALHREKAHVEETLAEIQVSL 2148
Cdd:COG3883     98 SGGSVSYLDVLLGSesfsdflDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAELEAQQ 177

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1720386946 2149 TRKDQEMKELQGSLDSTLAQLAAFTKSMSSLQDDRDRVIDEAKKWERRFGDAIQTKEEEVR 2209
Cdd:COG3883    178 AEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAAAA 238
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2523-2755 4.69e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.44  E-value: 4.69e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2523 NEVIAIKDSQQKQLLDAQLQQNKELRnectKLEERLKGLEAEKQSLQMSSDALQKEKQGLSKEIKNLQTQLTALQEEgtL 2602
Cdd:COG4942     19 ADAAAEAEAELEQLQQEIAELEKELA----ALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKE--I 92

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2603 GVYHAQLKAKEEELQRLnmaLSSSQKRTADLEEELVCVQKEATRKVSEIEDqLKKELKHLHHDAGIMRNETETAEERVAE 2682
Cdd:COG4942     93 AELRAELEAQKEELAEL---LRALYRLGRQPPLALLLSPEDFLDAVRRLQY-LKYLAPARREQAEELRADLAELAALRAE 168

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1720386946 2683 LARDLVEMEQKLLTVTKENKDLMAQIQAFGRSMSSLQDSRDHATEELGDLKKKYDASLKELAQLKEWQDSSRE 2755
Cdd:COG4942    169 LEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAE 241
PTZ00121 PTZ00121
MAEBL; Provisional
 47-505 4.80e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 42.82  E-value: 4.80e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946   47 ESTQEDALHRLAEAEKLVVELKdiisQKDVQLQQKDEALqeeKKAAENKIKKIKLhAKAKIMSLNKHMEEIKTQGGAALP 126
Cdd:PTZ00121  1300 EKKKADEAKKKAEEAKKADEAK----KKAEEAKKKADAA---KKKAEEAKKAAEA-AKAEAEAAADEAEAAEEKAEAAEK 1371

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  127 PEAQAEELSKHNKSSTEEEMEIEKIKHELQEKEKLISSLQAQLDQSEQASQLDKSSAEMEDFVLMKQQLQEKEELISTLQ 206
Cdd:PTZ00121  1372 KKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKK 1451

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  207 TQLSQTQAEQAAQVVREKDARFETQVRLHE----DELLQLVTQSDVETEMQQKLRVMQRKLEEHEEALLGRAqvvdllQK 282
Cdd:PTZ00121  1452 KAEEAKKAEEAKKKAEEAKKADEAKKKAEEakkaDEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKK------AD 1525

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  283 ELTSAEQRNQVLSQQLQLLEAEHNTLKNTMETERQESKTLMEKVELEvAERKLSFHNLQEEMHQLQGQLERAGQAQADLE 362
Cdd:PTZ00121  1526 EAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKA-EEDKNMALRKAEEAKKAEEARIEEVMKLYEEE 1604

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  363 TQYSALQQRHKTEMEEKTAcilSLQKNEQELQSACAALKEENSKLLQEKHDQAAESAQAMRqledQLQQKSKEISQFVNK 442
Cdd:PTZ00121  1605 KKMKAEEAKKAEEAKIKAE---ELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIK----AAEEAKKAEEDKKKA 1677

                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1720386946  443 PNLQKNETASQTSLPDVNNEGDQAVMEETVaslqKRVVELENEKGALLLSSGELEELKAENEK 505
Cdd:PTZ00121  1678 EEAKKAEEDEKKAAEALKKEAEEAKKAEEL----KKKEAEEKKKAEELKKAEEENKIKAEEAK 1736
PRK12704 PRK12704
phosphodiesterase; Provisional
 2051-2213 5.03e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 42.46  E-value: 5.03e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2051 HRKKAQAELSSFKILLDDTQsEAARVLADNLKLKKELQSNKESIKSQIKQKDEDLLRR--LEQAEEKHRKEKKNMQEKLD 2128
Cdd:PRK12704    25 RKKIAEAKIKEAEEEAKRIL-EEAKKEAEAIKKEALLEAKEEIHKLRNEFEKELRERRneLQKLEKRLLQKEENLDRKLE 103

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2129 ALHREKAHVEETLAEI---QVSLTRKDQEMKELQGSLDSTLAQLAAFTKsmsslQDDRDRVIDEAKKwERRFGDAIQTKE 2205
Cdd:PRK12704   104 LLEKREEELEKKEKELeqkQQELEKKEEELEELIEEQLQELERISGLTA-----EEAKEILLEKVEE-EARHEAAVLIKE 177


                   ....*...
gi 1720386946 2206 EEVRLKEE 2213
Cdd:PRK12704   178 IEEEAKEE 185
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 854-1077 5.27e-03

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 42.42  E-value: 5.27e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  854 QEMEGLSQALSQKELEIAKMDQLLLE--KQKDVETLQQTIQEKDQQVTElSFSMTEKMVQLNEEKFSLGVEIKTLKEQLN 931
Cdd:pfam17380  348 RELERIRQEERKRELERIRQEEIAMEisRMRELERLQMERQQKNERVRQ-ELEAARKVKILEEERQRKIQQQKVEMEQIR 426

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  932 llSRTEEATKEQVEESGAGSSLKLGHDESGQEGLQQELELLRKESEQRKRKLQAALINRKELLQKVSQLEEELAKVREDS 1011
Cdd:pfam17380  427 --AEQEEARQREVRRLEEERAREMERVRLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEEQRRKILEKELEER 504

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1720386946 1012 RKEIPFGENERRKLEEDRENRDdpeewgTSKWREVEASLKQTISEKEVELEGIRRDLKEKTAAEEE 1077
Cdd:pfam17380  505 KQAMIEEERKRKLLEKEMEERQ------KAIYEEERRREAEEERRKQQEMEERRRIQEQMRKATEE 564
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
2537-2968 5.33e-03

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 42.74  E-value: 5.33e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2537 LDAQLQQNKELRNECTKLEERLKGLEAEKQSLQMSSDALQKEKQGLSKEIKNLQTQLTALQE-----------EGTLGVY 2605
Cdd:PRK03918   226 LEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKElkekaeeyiklSEFYEEY 305

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2606 HAQLKAKEEELQRLNMALSSSQKRTADLE------EELVCVQKEATRKVSEIEDQLKKELKHLHHDAGIMRNETETAEER 2679
Cdd:PRK03918   306 LDELREIEKRLSRLEEEINGIEERIKELEekeerlEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLT 385

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2680 VAELARDLVEMEQKLLTVTKENKDLMAQIQAFGRSMSSLQDS---------------RDHATEELGDLKKKYDASLKELA 2744
Cdd:PRK03918   386 PEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAieelkkakgkcpvcgRELTEEHRKELLEEYTAELKRIE 465

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2745 -QLKEWQDSSREGDVLSQAAFPLSTSENVLSRLEKLNQQLTSKDEQLLHLSSE-LESSHNQVQSISKAMTSLQNERDRLW 2822
Cdd:PRK03918   466 kELKEIEEKERKLRKELRELEKVLKKESELIKLKELAEQLKELEEKLKKYNLEeLEKKAEEYEKLKEKLIKLKGEIKSLK 545

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2823 SELEKFrKSEEGKQRAAAPSAASSPAEVQSLKKAMSSL----QNDRDRLLKELKNLQQQYLQMSQEMTELRPLKAQLQES 2898
Cdd:PRK03918   546 KELEKL-EELKKKLAELEKKLDELEEELAELLKELEELgfesVEELEERLKELEPFYNEYLELKDAEKELEREEKELKKL 624

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1720386946 2899 QDQTKALQVMEEELRQENLSWQHELRQLRMEKNSWELHE-RRMKEQFLMAISDKDQQLGHLQSLLRELRSS 2968
Cdd:PRK03918   625 EEELDKAFEELAETEKRLEELRKELEELEKKYSEEEYEElREEYLELSRELAGLRAELEELEKRREEIKKT 695
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 754-986 5.82e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.06  E-value: 5.82e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  754 LAELRARVQELESSLAEAEKQRgldyESQRAQHNLLTEQIHSLSIEAKSKDVKIEALQRELDGVQlqfceqgTQMKTLQS 833
Cdd:COG4942     29 LEQLQQEIAELEKELAALKKEE----KALLKQLAALERRIAALARRIRALEQELAALEAELAELE-------KEIAELRA 97

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  834 QLEAKEREVRE---GTERLRDISQEMEGLSQA-LSQKELEIAKMDQLLLEKQKDVETLQQTIQEKDQQVTELSFSMTEKM 909
Cdd:COG4942     98 ELEAQKEELAEllrALYRLGRQPPLALLLSPEdFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELE 177

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  910 VQLNE---EKFSLGVEIKTLKEQLNLLSRTEEATKEQVEESgagsslklghdESGQEGLQQELELLRKESEQRKRKLQAA 986
Cdd:COG4942    178 ALLAEleeERAALEALKAERQKLLARLEKELAELAAELAEL-----------QQEAEELEALIARLEAEAAAAAERTPAA 246
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 211-1077 6.27e-03

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 42.27  E-value: 6.27e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  211 QTQAEQAAQVVREKDARFETQVRLHEdELLQLVTQSDVETEMQQKLRVMQRKLEEHEEALLGRAQVVDLLQKELTSAE-Q 289
Cdd:pfam02463  155 RLEIEEEAAGSRLKRKKKEALKKLIE-ETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYlK 233

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  290 RNQVLSQQLQLLEAEHNTLKNTMETERQESKTLMEKVELEVAERKLSFHNLQEEMHQLQGQLERAGQAQADLETQYSALQ 369
Cdd:pfam02463  234 LNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDE 313

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  370 QRHKTEMEEKTACILSLQKNEQELQSACAALKEENSKLLQEKH--DQAAESAQAMRQLEDQLQQKSKEISQFVNKPNLQK 447
Cdd:pfam02463  314 EKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEeeEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLK 393

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  448 NETASQTSLpDVNNEGDQAVMEETVASLQKRVVELENEKGALLLSSGELEELKAENEKLSSRITLLEAQNRAGEADGTVC 527
Cdd:pfam02463  394 EEELELKSE-EEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSED 472

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  528 EVSTAGTTLLNRSDSSPEENGQAVLENTFSQKHKELSVLLVEMKEAQEEIAFLKSQLQGkrpeGDYEVLDRREVQLMESE 607
Cdd:pfam02463  473 LLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRL----GDLGVAVENYKVAISTA 548

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  608 GPPSVTAGDVLCAPSDESSGPAAEEEQAGMKDRHRASEAGPLNDAGMELSSPKLDGVDKSLAVShvcQCHQGELERLKTQ 687
Cdd:pfam02463  549 VIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKAT---LEADEDDKRAKVV 625

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  688 VLELETSLHTAEETYKRNLSEKVKEISSLTQLSEEVKESAEEARSTLAAVTEERDQLLYQVKELDVLAELRARVQELESS 767
Cdd:pfam02463  626 EGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKE 705

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  768 LAEAEKQRGLDYESQRAQHNLLTEQIHSLSIEAKSKDVKIEALQRELDGVQLQFCEQGTQMKTLQSQLEAKEREVREGTE 847
Cdd:pfam02463  706 QREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEK 785

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  848 RLRDISQEMEGLSQALSQKELEIAKMDQLLLEKQKDVETLQQT-IQEKDQQVTELSFSMTEKMVQLNEEKFSLGVEIKTL 926
Cdd:pfam02463  786 LKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEkIKEEELEELALELKEEQKLEKLAEEELERLEEEITK 865

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  927 KEQLNLLSRTEEATKEQVEesgagsslklghdESGQEGLQQELELLRKESEQRKRKLQAALINRKELLQKVSQLEEELAK 1006
Cdd:pfam02463  866 EELLQELLLKEEELEEQKL-------------KDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLK 932

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1720386946 1007 VREDSRKEIPFGENERRKLEEDRENRDDPEEWGTSKWREVEASLKQTISEKEVELEGIRRDLKEKTAAEEE 1077
Cdd:pfam02463  933 YEEEPEELLLEEADEKEKEENNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEEE 1003
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1426-1616 6.51e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 42.31  E-value: 6.51e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1426 LEMQAKEHEERLKQAQVEICELKKK------PTELEEETNAKQQLQRKLQAALISRKEALKENKSLQEQLSSARDAVERL 1499
Cdd:COG3206    180 LEEQLPELRKELEEAEAALEEFRQKnglvdlSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLGSGPDALPEL 259

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1500 TKS--LADVESQVSVQNQEKDAVLGKLT-------ILQEERDKLIAEMdrflleNQSLSGSCESLKLALGGLTEDKEKLM 1570
Cdd:COG3206    260 LQSpvIQQLRAQLAELEAELAELSARYTpnhpdviALRAQIAALRAQL------QQEAQRILASLEAELEALQAREASLQ 333

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*.
gi 1720386946 1571 EELESVRSsKMAESTEWQEKHKELQKEYEVLLQSYENVSNEAERIQ 1616
Cdd:COG3206    334 AQLAQLEA-RLAELPELEAELRRLEREVEVARELYESLLQRLEEAR 378
46 PHA02562
endonuclease subunit; Provisional
 1818-2008 6.81e-03

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 41.92  E-value: 6.81e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1818 KNYLQQLDQLKG-RIAELEMEKQKDRELSQALENEKNALLTQISAKDSELKLLEEEVTKRTTLNQQIQEELCRVTKLKET 1896
Cdd:PHA02562   201 NKNIEEQRKKNGeNIARKQNKYDELVEEAKTIKAEIEELTDELLNLVMDIEDPSAALNKLNTAAAKIKSKIEQFQKVIKM 280

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1897 AEE------------EKDDLEERLMNQLAELNGSignyYQDVTDAQIKNEQLESEMRNLQRCVSEL----EEEKQQL--- 1957
Cdd:PHA02562   281 YEKggvcptctqqisEGPDRITKIKDKLKELQHS----LEKLDTAIDELEEIMDEFNEQSKKLLELknkiSTNKQSLitl 356

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1720386946 1958 VKEKTKVESEIRKeymekiqgAQKGPANksHAKELQELLREKQQEVKQLQK 2008
Cdd:PHA02562   357 VDKAKKVKAAIEE--------LQAEFVD--NAEELAKLQDELDKIVKTKSE 397
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1149-1625 7.33e-03

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 41.93  E-value: 7.33e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1149 ELEGRILDLEKDKTQLQK---KLQEALIARKAILKKAQEKEKQLKEELREQKDAYHHLQGQFHEQNKEKENIADQLRQLQ 1225
Cdd:TIGR04523  215 SLESQISELKKQNNQLKDnieKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLK 294

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1226 CQAREsidrqlpgtgqqepgppapsLEGISLEDTEPASESDLHAAQPS-PPGETAALQATVSVAQIQAQLKEMEVEKEEL 1304
Cdd:TIGR04523  295 SEISD--------------------LNNQKEQDWNKELKSELKNQEKKlEEIQNQISQNNKIISQLNEQISQLKKELTNS 354

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1305 ELKVSSIASELAKKSEEVLLLQDQINEQGLEIQNLKAASVEAQahTELLKQELESSQLKvaglEHLKTLQPELDALHKHM 1384
Cdd:TIGR04523  355 ESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLE--SKIQNQEKLNQQKD----EQIKKLQQEKELLEKEI 428

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1385 GQKEEEVNYLYGQLSEKEQTLTTVQTEMVEQERLIKALHTQLEMQAKEHEERLKQAQVEICELKKKPTELEEETNAKQQL 1464
Cdd:TIGR04523  429 ERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKEL 508

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1465 QrklqaalisrkealKENKSLQEQLSSARDAVERLTKSLADVESQVSVQNQEKDAVLGKLT--ILQEERDKLIAEMDRFL 1542
Cdd:TIGR04523  509 E--------------EKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDFELKkeNLEKEIDEKNKEIEELK 574

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1543 LENQSLSGSCESLKLALGGLTEDKEKLMEELEsvrsSKMAESTEWQEKHKELQKEYEVLLQSYENVSNEAERIQHVVESV 1622
Cdd:TIGR04523  575 QTQKSLKKKQEEKQELIDQKEKEKKDLIKEIE----EKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQI 650


                   ...
gi 1720386946 1623 RQE 1625
Cdd:TIGR04523  651 KET 653
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 2573-2830 7.67e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 41.67  E-value: 7.67e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2573 DALQKEKQGLSKEIKNLQTQLTALQeegtlgvyhAQLKAKEEELQRLNMALSSSQKRTADLEEELvcvqKEATRKVSEIE 2652
Cdd:COG4942     23 AEAEAELEQLQQEIAELEKELAALK---------KEEKALLKQLAALERRIAALARRIRALEQEL----AALEAELAELE 89

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2653 DQLKKelkhlhhdagiMRNETETAEERVAELARDLVEMEQKLLTVTKENKDLMAQIQAFGRSMSSLQDSRDHATEELGDL 2732
Cdd:COG4942     90 KEIAE-----------LRAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRAD 158

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2733 KKKYDASLKELAQLKEWQDSSREgdvlsqaafplstseNVLSRLEKLNQQLTSKDEQLLHLSSELESSHNQVQSISKAMT 2812
Cdd:COG4942    159 LAELAALRAELEAERAELEALLA---------------ELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAE 223

                          250
                   ....*....|....*...
gi 1720386946 2813 SLQNERDRLWSELEKFRK 2830
Cdd:COG4942    224 ELEALIARLEAEAAAAAE 241
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1337-1519 7.78e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 41.93  E-value: 7.78e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1337 QNLKAASVEAQAHTELLKQELESSQLKVAGLEH-LKTLQPELDALhkhmgQKEEEVNYLYGQLSEKEQTLTTVQTEMVEQ 1415
Cdd:COG3206    164 QNLELRREEARKALEFLEEQLPELRKELEEAEAaLEEFRQKNGLV-----DLSEEAKLLLQQLSELESQLAEARAELAEA 238

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1416 ERLIKALHTQLEMQA------------KEHEERLKQAQVEICELKKKPTE--------LEEETNAKQQLQRKLQAALISR 1475
Cdd:COG3206    239 EARLAALRAQLGSGPdalpellqspviQQLRAQLAELEAELAELSARYTPnhpdvialRAQIAALRAQLQQEAQRILASL 318

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....
gi 1720386946 1476 KEALKENKSLQEQLSSARDAVERLTKSLADVESQVSVQNQEKDA 1519
Cdd:COG3206    319 EAELEALQAREASLQAQLAQLEARLAELPELEAELRRLEREVEV 362
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 154-436 7.79e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 41.98  E-value: 7.79e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  154 ELQEKEKLISSLQAQLDQSEqaSQLDKSSAEMEDfvlMKQQLQEKEELISTLQTQLSQTQAEQAAQVVREKDARFETQVR 233
Cdd:TIGR02169  724 EIEQLEQEEEKLKERLEELE--EDLSSLEQEIEN---VKSELKELEARIEELEEDLHKLEEALNDLEARLSHSRIPEIQA 798

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  234 LHEDELLQLVTQSDVETEMQQKLRVMQRKLEEHEEALLGRAQVVDLLQKELTSAEQRNQVLSQQLQLLEAEhntLKNTME 313
Cdd:TIGR02169  799 ELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEE---LEELEA 875

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  314 TERQESKTLmEKVELEVAERKLSFHNLQEEMHQLQGQLERAGQAQADLETQYSALQQRHKT------EMEEKTACILSL- 386
Cdd:TIGR02169  876 ALRDLESRL-GDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEiedpkgEDEEIPEEELSLe 954

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1720386946  387 --QKNEQELQSACAALKEENSKL-------------LQEKHDQAAESAQAMRQLEDQLQQKSKEI 436
Cdd:TIGR02169  955 dvQAELQRVEEEIRALEPVNMLAiqeyeevlkrldeLKEKRAKLEEERKAILERIEEYEKKKREV 1019
Crescentin pfam19220
Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament ...
 680-873 7.84e-03

Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament proteins, named crescentin, whose cytoskeletal function is required for the vibrioid and helical shapes of Caulobacter crescentus. Without crescentin, the cells adopt a straight-rod morphology. Crescentin has characteriztic features of IF proteins including the ability to assemble into filaments in vitro without energy or cofactor requirements. In vivo, crescentin forms a helical structure that colocalizes with the inner cell curvatures beneath the cytoplasmic membrane.


Pssm-ID: 437057 [Multi-domain]  Cd Length: 401  Bit Score: 41.59  E-value: 7.84e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  680 ELERLKTQVLELETSLHTAEETYkRNLSEKVKEISS-LTQLSEEVKESAEEARSTLAAVTEERdqllyqvkelDVLAELR 758
Cdd:pfam19220   42 ELPQAKSRLLELEALLAQERAAY-GKLRRELAGLTRrLSAAEGELEELVARLAKLEAALREAE----------AAKEELR 110

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  759 ARVQELESSLAEAEKQrgLDYESQRAQHnlLTEQIHSLSIEAKSKDVKIEALQRELDGVQLQFCEQGTQMKTLQSQLEAK 838
Cdd:pfam19220  111 IELRDKTAQAEALERQ--LAAETEQNRA--LEEENKALREEAQAAEKALQRAEGELATARERLALLEQENRRLQALSEEQ 186

                          170       180       190
                   ....*....|....*....|....*....|....*
gi 1720386946  839 EREVREGTERLRDISQEMEGLSQALSQKELEIAKM 873
Cdd:pfam19220  187 AAELAELTRRLAELETQLDATRARLRALEGQLAAE 221
mukB PRK04863
chromosome partition protein MukB;
2339-2686 8.64e-03

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 41.87  E-value: 8.64e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2339 EQLETDLAASRELTSRLHDEINAKEQKIISLLSGKEEAI--QLAV------EELHQQHSKEIKELENLLSQEEeenvale 2410
Cdd:PRK04863   785 EKRIEQLRAEREELAERYATLSFDVQKLQRLHQAFSRFIgsHLAVafeadpEAELRQLNRRRVELERALADHE------- 857

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2411 eenkralEKTNQLTEALEAIKkesfEQKAQLDSFVKSMSSLQDDR--DRIvsdyRQLEERhLSAILEKDQLIQDAAAENN 2488
Cdd:PRK04863   858 -------SQEQQQRSQLEQAK----EGLSALNRLLPRLNLLADETlaDRV----EEIREQ-LDEAEEAKRFVQQHGNALA 921

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2489 KLKEEMRGLRS---HMDDLNSENAKLDAELVQYR---RDLNEVIAIK------DSQQKQLLDAQL-----QQNKELRNEC 2551
Cdd:PRK04863   922 QLEPIVSVLQSdpeQFEQLKQDYQQAQQTQRDAKqqaFALTEVVQRRahfsyeDAAEMLAKNSDLneklrQRLEQAEQER 1001

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2552 TKLEERLKGLEAE-------KQSLQMSSDALQKEKQGLSKEIKNLQTQLTALQEEgtlgvyhaQLKAKEEElqrLNMALS 2624
Cdd:PRK04863  1002 TRAREQLRQAQAQlaqynqvLASLKSSYDAKRQMLQELKQELQDLGVPADSGAEE--------RARARRDE---LHARLS 1070

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1720386946 2625 SSQKRTADLEEELVCVQKEAtrkvseieDQLKKELKHLHHDAGIMRNETETAEER---VAELARD 2686
Cdd:PRK04863  1071 ANRSRRNQLEKQLTFCEAEM--------DNLTKKLRKLERDYHEMREQVVNAKAGwcaVLRLVKD 1127
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1807-2292 8.79e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 41.82  E-value: 8.79e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1807 VSETFSSHDDIKNYLQQLDQLKGRI----AELEMEKQKDRElsQALENEKNALLTQISAKDSELKLLEEEVTK-RTTLNQ 1881
Cdd:COG4913    257 IRELAERYAAARERLAELEYLRAALrlwfAQRRLELLEAEL--EELRAELARLEAELERLEARLDALREELDElEAQIRG 334

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1882 QIQEELCRVTKLKETAEEEKDDLEERLmNQLAELNGSIGnyYQDVTDAqiknEQLESEMRNLQRCVSELEEEKQQLVKEK 1961
Cdd:COG4913    335 NGGDRLEQLEREIERLERELEERERRR-ARLEALLAALG--LPLPASA----EEFAALRAEAAALLEALEEELEALEEAL 407

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 1962 TKVESEIRkeymekiqgaqkgpankshakELQELLREKQQEVKQLQ--KDCI-RYLERI-----SALEKTVKALEF---- 2029
Cdd:COG4913    408 AEAEAALR---------------------DLRRELRELEAEIASLErrKSNIpARLLALrdalaEALGLDEAELPFvgel 466

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2030 --VHTESQK--------------DLDVTKGNLAQAVEH--RKKAQAELSSFKILLDDTQSEAARVLADNLKLKKELQSNK 2091
Cdd:COG4913    467 ieVRPEEERwrgaiervlggfalTLLVPPEHYAAALRWvnRLHLRGRLVYERVRTGLPDPERPRLDPDSLAGKLDFKPHP 546

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2092 --ESIKSQIKQK-------DEDLLRRLEQA--------EEKHRKEKK-------------NMQEKLDALHREKAHVEETL 2141
Cdd:COG4913    547 frAWLEAELGRRfdyvcvdSPEELRRHPRAitragqvkGNGTRHEKDdrrrirsryvlgfDNRAKLAALEAELAELEEEL 626

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2142 AEIQVSLTRKDQEMKELQGSLDsTLAQLAAFT----------KSMSSLQDDRDRV------IDEAKKWERRFGDAIQTKE 2205
Cdd:COG4913    627 AEAEERLEALEAELDALQERRE-ALQRLAEYSwdeidvasaeREIAELEAELERLdassddLAALEEQLEELEAELEELE 705

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946 2206 EEVRLKEENCIALKDQLRQMAIHMEELKITVSRLEHDKEIWESKAQTELQHHQKAYDKLQEENKELTSQLEDARQLYHDS 2285
Cdd:COG4913    706 EELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGDAVERELRENLEERIDALRARLNRA 785


                   ....*..
gi 1720386946 2286 KNELTKL 2292
Cdd:COG4913    786 EEELERA 792
HMMR_N pfam15905
Hyaluronan mediated motility receptor N-terminal; HMMR_N is the N-terminal region of ...
 789-931 9.25e-03

Hyaluronan mediated motility receptor N-terminal; HMMR_N is the N-terminal region of eukaryotic hyaluronan-mediated motility receptor proteins. The protein is functionally associated with BRCA1 and thus predicted to be a common, low-penetrance breast cancer candidate.


Pssm-ID: 464932 [Multi-domain]  Cd Length: 329  Bit Score: 41.34  E-value: 9.25e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  789 LTEQIHSLSIEAKSKDVKIEALQRELDGVQLQFCEQGTQMKTLQSQLEAKEREVRE---GTERLRDISQEMEGLSQALSQ 865
Cdd:pfam15905  161 LMKLRNKLEAKMKEVMAKQEGMEGKLQVTQKNLEHSKGKVAQLEEKLVSTEKEKIEeksETEKLLEYITELSCVSEQVEK 240

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1720386946  866 KELEIAKMDQLLLEKQKDVETLQQTIQEKDQQVTELSFSMTEKMVQLNEEKFSLGVEIKTLKEQLN 931
Cdd:pfam15905  241 YKLDIAQLEELLKEKNDEIESLKQSLEEKEQELSKQIKDLNEKCKLLESEKEELLREYEEKEQTLN 306
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 239-453 9.36e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 41.29  E-value: 9.36e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  239 LLQLVTQSDVETEMQQKLRVMQRKLEEHEEALLGRAQVVDLLQKELTSAEQRNQVLSQQLQLLEAEHNTLK---NTMETE 315
Cdd:COG4942     12 ALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEaelAELEKE 91

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720386946  316 RQESKTLMEKVELEVAER---------------KLSFHNLQEEMHQLQ--GQLERAGQAQADLETQYSALQQRHKTEMEE 378
Cdd:COG4942     92 IAELRAELEAQKEELAELlralyrlgrqpplalLLSPEDFLDAVRRLQylKYLAPARREQAEELRADLAELAALRAELEA 171

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1720386946  379 KTACILSLQKNEQELQSACAALKEENSKLLQEKHDQAAESAQAMRQLEDQLQQKSKEISQFVNKPNLQKNETASQ 453
Cdd:COG4942    172 ERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAA 246
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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