NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1720389887|ref|XP_030105598|]
View 

disks large-associated protein 1 isoform X4 [Mus musculus]

Protein Classification

disks large-associated family protein( domain architecture ID 11141961)

disks large-associated family protein functions as a membrane-associated guanylate kinases

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

Name Accession Description Interval E-value
GKAP pfam03359
Guanylate-kinase-associated protein (GKAP) protein;
660-992 0e+00

Guanylate-kinase-associated protein (GKAP) protein;


:

Pssm-ID: 460897  Cd Length: 341  Bit Score: 561.66  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720389887 660 KKNRCLSIGIQVDDAEEP-EKMAESKTSNKFQSVGVQVEEEKCFRRFTRSNSVTTAVQADLDFHDNLENSLESIEDNS-- 736
Cdd:pfam03359   1 PKKKRSSIGIQVDCIETVsDSDEESKPLREFQSIGVQVEDDKRRARFKRSNSVTAAVQADLELEGFPGLSLEVPTEDKgl 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720389887 737 -CPGPMARQFSRDASTSTVSIQGSGNHYHACAADDDFDTDFDPSILPPPDPWIDSiTEDPLE--AVQRSVCHRDGHWFLK 813
Cdd:pfam03359  81 qFGGSFQRHSSEPASTSQYSIQRSVHTQGQWAYREDYDPALDPSSLPPPDPWLED-GPRSLPdsGRASPVCRRDGEWFLK 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720389887 814 LLQAERDRMEGWCKLMEREERENNLPEDILGKIRTAVGSAQLLMAQKFYQFRELCEENLNPNAHPRPTSQDLAGFWDMLQ 893
Cdd:pfam03359 160 LLQAETERMEGWCQQMEREAEENDLPEEILGKIRSAVGSAQLLMSQKFQQFRGLCEQNLNPNANPRPTSQDLAGFWDLLQ 239
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720389887 894 LSIENISMKFDELHQLKANNWKQMDPLDKKE-RRAPPPVPKKPAKGPAPLIRERSLESS--QRQEARKRLMAAKRAASVR 970
Cdd:pfam03359 240 LSIEDISMKFDELHQLKANNWKLEDPPEKKEnKKLPPPVPKKPSKGRPPLVRERSLDSVdrQRQEARKRLMAAKRAASVR 319
                         330       340
                  ....*....|....*....|..
gi 1720389887 971 QNSATESAESIEIYIPEAQTRL 992
Cdd:pfam03359 320 QNSATESADSIEIYIPEAQTRL 341
 
Name Accession Description Interval E-value
GKAP pfam03359
Guanylate-kinase-associated protein (GKAP) protein;
660-992 0e+00

Guanylate-kinase-associated protein (GKAP) protein;


Pssm-ID: 460897  Cd Length: 341  Bit Score: 561.66  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720389887 660 KKNRCLSIGIQVDDAEEP-EKMAESKTSNKFQSVGVQVEEEKCFRRFTRSNSVTTAVQADLDFHDNLENSLESIEDNS-- 736
Cdd:pfam03359   1 PKKKRSSIGIQVDCIETVsDSDEESKPLREFQSIGVQVEDDKRRARFKRSNSVTAAVQADLELEGFPGLSLEVPTEDKgl 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720389887 737 -CPGPMARQFSRDASTSTVSIQGSGNHYHACAADDDFDTDFDPSILPPPDPWIDSiTEDPLE--AVQRSVCHRDGHWFLK 813
Cdd:pfam03359  81 qFGGSFQRHSSEPASTSQYSIQRSVHTQGQWAYREDYDPALDPSSLPPPDPWLED-GPRSLPdsGRASPVCRRDGEWFLK 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720389887 814 LLQAERDRMEGWCKLMEREERENNLPEDILGKIRTAVGSAQLLMAQKFYQFRELCEENLNPNAHPRPTSQDLAGFWDMLQ 893
Cdd:pfam03359 160 LLQAETERMEGWCQQMEREAEENDLPEEILGKIRSAVGSAQLLMSQKFQQFRGLCEQNLNPNANPRPTSQDLAGFWDLLQ 239
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720389887 894 LSIENISMKFDELHQLKANNWKQMDPLDKKE-RRAPPPVPKKPAKGPAPLIRERSLESS--QRQEARKRLMAAKRAASVR 970
Cdd:pfam03359 240 LSIEDISMKFDELHQLKANNWKLEDPPEKKEnKKLPPPVPKKPSKGRPPLVRERSLDSVdrQRQEARKRLMAAKRAASVR 319
                         330       340
                  ....*....|....*....|..
gi 1720389887 971 QNSATESAESIEIYIPEAQTRL 992
Cdd:pfam03359 320 QNSATESADSIEIYIPEAQTRL 341
 
Name Accession Description Interval E-value
GKAP pfam03359
Guanylate-kinase-associated protein (GKAP) protein;
660-992 0e+00

Guanylate-kinase-associated protein (GKAP) protein;


Pssm-ID: 460897  Cd Length: 341  Bit Score: 561.66  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720389887 660 KKNRCLSIGIQVDDAEEP-EKMAESKTSNKFQSVGVQVEEEKCFRRFTRSNSVTTAVQADLDFHDNLENSLESIEDNS-- 736
Cdd:pfam03359   1 PKKKRSSIGIQVDCIETVsDSDEESKPLREFQSIGVQVEDDKRRARFKRSNSVTAAVQADLELEGFPGLSLEVPTEDKgl 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720389887 737 -CPGPMARQFSRDASTSTVSIQGSGNHYHACAADDDFDTDFDPSILPPPDPWIDSiTEDPLE--AVQRSVCHRDGHWFLK 813
Cdd:pfam03359  81 qFGGSFQRHSSEPASTSQYSIQRSVHTQGQWAYREDYDPALDPSSLPPPDPWLED-GPRSLPdsGRASPVCRRDGEWFLK 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720389887 814 LLQAERDRMEGWCKLMEREERENNLPEDILGKIRTAVGSAQLLMAQKFYQFRELCEENLNPNAHPRPTSQDLAGFWDMLQ 893
Cdd:pfam03359 160 LLQAETERMEGWCQQMEREAEENDLPEEILGKIRSAVGSAQLLMSQKFQQFRGLCEQNLNPNANPRPTSQDLAGFWDLLQ 239
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720389887 894 LSIENISMKFDELHQLKANNWKQMDPLDKKE-RRAPPPVPKKPAKGPAPLIRERSLESS--QRQEARKRLMAAKRAASVR 970
Cdd:pfam03359 240 LSIEDISMKFDELHQLKANNWKLEDPPEKKEnKKLPPPVPKKPSKGRPPLVRERSLDSVdrQRQEARKRLMAAKRAASVR 319
                         330       340
                  ....*....|....*....|..
gi 1720389887 971 QNSATESAESIEIYIPEAQTRL 992
Cdd:pfam03359 320 QNSATESADSIEIYIPEAQTRL 341
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH