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Conserved domains on  [gi|1720398793|ref|XP_030106360|]
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spermine oxidase isoform X11 [Mus musculus]

Protein Classification

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
PLN02568 super family cl33517
polyamine oxidase
50-411 2.19e-58

polyamine oxidase


The actual alignment was detected with superfamily member PLN02568:

Pssm-ID: 215308 [Multi-domain]  Cd Length: 539  Bit Score: 199.67  E-value: 2.19e-58
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720398793  50 DVTVLEASSHIGGRVQSVRLDT-TFELGATWIHGSHGNPIYQLAEANGLLEETTDGERSVGriSLYSKNGVAcyltNRGC 128
Cdd:PLN02568   35 ELTVVEGGDRIGGRINTSEFGGeRIEMGATWIHGIGGSPVYKIAQEAGSLESDEPWECMDG--FPDRPKTVA----EGGF 108
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720398793 129 RIPKDVVEEFSDLYNEVYNMTQ---------EFFRHGKPVNAESQ-------NSVGVFTREKVRNrIRDDPDDTEATKR- 191
Cdd:PLN02568  109 EVDPSIVESISTLFRGLMDDAQgkliepsevDEVDFVKLAAKAARvcesgggGSVGSFLRRGLDA-YWDSVSADEQIKGy 187
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720398793 192 -------LKLAMIQQYLKVESCESSSHSIDEVSLSAFGEWTEIPGAHHIIPSGFMRVVELLAEGIPPHVIQLGKPVRCIH 264
Cdd:PLN02568  188 ggwsrklLEEAIFTMHENTQRTYTSADDLSTLDLAAESEYRMFPGEEITIAKGYLSVIEALASVLPPGTIQLGRKVTRIE 267
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720398793 265 W-----------------------------------DQASAHPRGP--------------------EIEPR-----ERYG 284
Cdd:PLN02568  268 WqdepvklhfadgstmtadhvivtvslgvlkagigeDSGLFSPPLPdfktdaisrlgfgvvnklfvELSPRpdgspEDVA 347
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720398793 285 H--------------------------------------VLSGWICGEEALVMERCDDEAVAEICTEMLRQFTGNPNIP- 325
Cdd:PLN02568  348 KfpflqmafhrsdsearhdkipwwmrrtasicpihknssVLLSWFAGKEALELEKLSDEEIIRGVQTTLSSFLKRRVAGl 427
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720398793 326 --------------------KPRRILRSAWGSNPYFRGSYSYTQVGSSGADVEKLAKPLPYT---ESSKTAPMQVLFSGE 382
Cdd:PLN02568  428 gsqshplcnggassndgsrwKFVKVLKSKWGTDPLFLGSYSYVAVGSSGDDLDRMAEPLPRIsdhDQAGGPPLQLLFAGE 507
                         490       500
                  ....*....|....*....|....*....
gi 1720398793 383 ATHRKYYSTTHGALLSGQREAARLIEMYR 411
Cdd:PLN02568  508 ATHRTHYSTTHGAYFSGLREANRLLQHYK 536
 
Name Accession Description Interval E-value
PLN02568 PLN02568
polyamine oxidase
50-411 2.19e-58

polyamine oxidase


Pssm-ID: 215308 [Multi-domain]  Cd Length: 539  Bit Score: 199.67  E-value: 2.19e-58
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720398793  50 DVTVLEASSHIGGRVQSVRLDT-TFELGATWIHGSHGNPIYQLAEANGLLEETTDGERSVGriSLYSKNGVAcyltNRGC 128
Cdd:PLN02568   35 ELTVVEGGDRIGGRINTSEFGGeRIEMGATWIHGIGGSPVYKIAQEAGSLESDEPWECMDG--FPDRPKTVA----EGGF 108
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720398793 129 RIPKDVVEEFSDLYNEVYNMTQ---------EFFRHGKPVNAESQ-------NSVGVFTREKVRNrIRDDPDDTEATKR- 191
Cdd:PLN02568  109 EVDPSIVESISTLFRGLMDDAQgkliepsevDEVDFVKLAAKAARvcesgggGSVGSFLRRGLDA-YWDSVSADEQIKGy 187
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720398793 192 -------LKLAMIQQYLKVESCESSSHSIDEVSLSAFGEWTEIPGAHHIIPSGFMRVVELLAEGIPPHVIQLGKPVRCIH 264
Cdd:PLN02568  188 ggwsrklLEEAIFTMHENTQRTYTSADDLSTLDLAAESEYRMFPGEEITIAKGYLSVIEALASVLPPGTIQLGRKVTRIE 267
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720398793 265 W-----------------------------------DQASAHPRGP--------------------EIEPR-----ERYG 284
Cdd:PLN02568  268 WqdepvklhfadgstmtadhvivtvslgvlkagigeDSGLFSPPLPdfktdaisrlgfgvvnklfvELSPRpdgspEDVA 347
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720398793 285 H--------------------------------------VLSGWICGEEALVMERCDDEAVAEICTEMLRQFTGNPNIP- 325
Cdd:PLN02568  348 KfpflqmafhrsdsearhdkipwwmrrtasicpihknssVLLSWFAGKEALELEKLSDEEIIRGVQTTLSSFLKRRVAGl 427
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720398793 326 --------------------KPRRILRSAWGSNPYFRGSYSYTQVGSSGADVEKLAKPLPYT---ESSKTAPMQVLFSGE 382
Cdd:PLN02568  428 gsqshplcnggassndgsrwKFVKVLKSKWGTDPLFLGSYSYVAVGSSGDDLDRMAEPLPRIsdhDQAGGPPLQLLFAGE 507
                         490       500
                  ....*....|....*....|....*....
gi 1720398793 383 ATHRKYYSTTHGALLSGQREAARLIEMYR 411
Cdd:PLN02568  508 ATHRTHYSTTHGAYFSGLREANRLLQHYK 536
Amino_oxidase pfam01593
Flavin containing amine oxidoreductase; This family consists of various amine oxidases, ...
45-407 8.83e-37

Flavin containing amine oxidoreductase; This family consists of various amine oxidases, including maze polyamine oxidase (PAO)and various flavin containing monoamine oxidases (MAO). The aligned region includes the flavin binding site of these enzymes. The family also contains phytoene dehydrogenases and related enzymes. In vertebrates MAO plays an important role regulating the intracellular levels of amines via there oxidation; these include various neurotransmitters, neurotoxins and trace amines. In lower eukaryotes such as aspergillus and in bacteria the main role of amine oxidases is to provide a source of ammonium. PAOs in plants, bacteria and protozoa oxidase spermidine and spermine to an aminobutyral, diaminopropane and hydrogen peroxide and are involved in the catabolism of polyamines. Other members of this family include tryptophan 2-monooxygenase, putrescine oxidase, corticosteroid binding proteins and antibacterial glycoproteins.


Pssm-ID: 396255 [Multi-domain]  Cd Length: 446  Bit Score: 139.55  E-value: 8.83e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720398793  45 EQGFtDVTVLEASSHIGGRVQSVRLD-TTFELGATWIHGSHgNPIYQLAEANGLLEETTDGERSVGRIslyskngvacYL 123
Cdd:pfam01593  12 RAGH-DVTVLEARDRVGGRIRTVRDDgFLIELGAMWFHGAQ-PPLLALLKELGLEDRLVLPDPAPFYT----------VL 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720398793 124 TNRGCRIPKDvveeFSDLYNEVynmtQEFFRHGKPVNAES--QNSVGVFTREKVRNRIRDDPDDTEATKRLK-------- 193
Cdd:pfam01593  80 FAGGRRYPGD----FRRVPAGW----EGLLEFGRLLSIPEklRLGLAALASDALDEFDLDDFSLAESLLFLGrrgpgdve 151
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720398793 194 ----LAMIQQYLKVESCeSSSHSIDEVSLSAFGEW-----TEIPGAHHIIPSGFM-RVVELLAEGIPPHVIQLGKPVRCI 263
Cdd:pfam01593 152 vwdrLIDPELFAALPFA-SGAFAGDPSELSAGLALpllwaLLGEGGSLLLPRGGLgALPDALAAQLLGGDVRLNTRVRSI 230
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720398793 264 H------------------------------------------------------------------WDQASAHPRGPEI 277
Cdd:pfam01593 231 DregdgvtvtltdgevieadavivtvplgvlkrilftpplppekarairnlgygpvnkvhlefdrkfWPDLGLLGLLSEL 310
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720398793 278 -------------EPRERYGH--VLSGWI-CGEEALVMERCDDEAVAEICTEMLRQFTGnPNIPKPRRILRSAWGSNPYF 341
Cdd:pfam01593 311 ltglgtafswltfPNRAPPGKglLLLVYVgPGDRARELEGLSDEELLQAVLRDLRKLFG-EEAPEPLRVLVSDWHTDPWP 389
                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1720398793 342 RGSYSYTQVGSSGADVEKLAKPLpytessktAPmQVLFSGEATHRKYYSTTHGALLSGQREAARLI 407
Cdd:pfam01593 390 RGSYSLPQYGPGHDDYRPLARTP--------DP-GLFFAGEHTSTGYPGTVEGAIESGRRAARAVL 446
YobN COG1231
Monoamine oxidase [Amino acid transport and metabolism];
50-408 8.21e-29

Monoamine oxidase [Amino acid transport and metabolism];


Pssm-ID: 440844 [Multi-domain]  Cd Length: 440  Bit Score: 116.94  E-value: 8.21e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720398793  50 DVTVLEASSHIGGRVQSVRLDTT---FELGATWIHGSHGNpIYQLAEANGLleETTDGERSVGRiSLYSKNGVACYLtnr 126
Cdd:COG1231    32 DVTVLEARDRVGGRVWTLRFGDDglyAELGAMRIPPSHTN-LLALARELGL--PLEPFPNENGN-ALLYLGGKRVRA--- 104
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720398793 127 gcRIPKDVVEEFSDLYNE-VYNMTQEFFRHGKPVNAESQNSVGVFtrekvrnrIRDDPDDTEAtkrlkLAMIQQYLKVES 205
Cdd:COG1231   105 --GEIAADLRGVAELLAKlLRALAAALDPWAHPAAELDRESLAEW--------LRRNGASPSA-----RRLLGLLGAGEY 169
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720398793 206 CESSshsiDEVSLSAF---GEWTEIPGAHHIIPSGFMRVVELLAEGIPPHvIQLGKPVRCIHWDQAS---AHPRGPEIE- 278
Cdd:COG1231   170 GADP----DELSLLDLlryAASAGGGAQQFRIVGGMDQLPRALAAELGDR-IRLGAPVTRIRQDGDGvtvTTDDGGTVRa 244
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720398793 279 ---------------------PRER--------YGH-------------------------------------------- 285
Cdd:COG1231   245 davivtvppsvlrriefdpplPAAKraaiqrlpYGAaikvflqfdrpfweedglyggisltdlpirqtwypsngpdggag 324
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720398793 286 VLSGWICGEEALVMERCDDEAVAEICTEMLRQFTGNPnIPKPRRILRSAWGSNPYFRGSYSYTQVGSSGADVEKLAKPLP 365
Cdd:COG1231   325 VLLGYVGGDDARALAALSPEERVAAALEQLARIFGVY-AAEPVDYVSTDWGRDPWSRGAYAAAPPGQLTAAGPALAEPDG 403
                         410       420       430       440
                  ....*....|....*....|....*....|....*....|...
gi 1720398793 366 ytessktapmQVLFSGEATHRKYYSTTHGALLSGQREAARLIE 408
Cdd:COG1231   404 ----------RIHFAGEHTSDEWPGWVEGALESGERAAAEILA 436
 
Name Accession Description Interval E-value
PLN02568 PLN02568
polyamine oxidase
50-411 2.19e-58

polyamine oxidase


Pssm-ID: 215308 [Multi-domain]  Cd Length: 539  Bit Score: 199.67  E-value: 2.19e-58
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720398793  50 DVTVLEASSHIGGRVQSVRLDT-TFELGATWIHGSHGNPIYQLAEANGLLEETTDGERSVGriSLYSKNGVAcyltNRGC 128
Cdd:PLN02568   35 ELTVVEGGDRIGGRINTSEFGGeRIEMGATWIHGIGGSPVYKIAQEAGSLESDEPWECMDG--FPDRPKTVA----EGGF 108
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720398793 129 RIPKDVVEEFSDLYNEVYNMTQ---------EFFRHGKPVNAESQ-------NSVGVFTREKVRNrIRDDPDDTEATKR- 191
Cdd:PLN02568  109 EVDPSIVESISTLFRGLMDDAQgkliepsevDEVDFVKLAAKAARvcesgggGSVGSFLRRGLDA-YWDSVSADEQIKGy 187
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720398793 192 -------LKLAMIQQYLKVESCESSSHSIDEVSLSAFGEWTEIPGAHHIIPSGFMRVVELLAEGIPPHVIQLGKPVRCIH 264
Cdd:PLN02568  188 ggwsrklLEEAIFTMHENTQRTYTSADDLSTLDLAAESEYRMFPGEEITIAKGYLSVIEALASVLPPGTIQLGRKVTRIE 267
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720398793 265 W-----------------------------------DQASAHPRGP--------------------EIEPR-----ERYG 284
Cdd:PLN02568  268 WqdepvklhfadgstmtadhvivtvslgvlkagigeDSGLFSPPLPdfktdaisrlgfgvvnklfvELSPRpdgspEDVA 347
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720398793 285 H--------------------------------------VLSGWICGEEALVMERCDDEAVAEICTEMLRQFTGNPNIP- 325
Cdd:PLN02568  348 KfpflqmafhrsdsearhdkipwwmrrtasicpihknssVLLSWFAGKEALELEKLSDEEIIRGVQTTLSSFLKRRVAGl 427
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720398793 326 --------------------KPRRILRSAWGSNPYFRGSYSYTQVGSSGADVEKLAKPLPYT---ESSKTAPMQVLFSGE 382
Cdd:PLN02568  428 gsqshplcnggassndgsrwKFVKVLKSKWGTDPLFLGSYSYVAVGSSGDDLDRMAEPLPRIsdhDQAGGPPLQLLFAGE 507
                         490       500
                  ....*....|....*....|....*....
gi 1720398793 383 ATHRKYYSTTHGALLSGQREAARLIEMYR 411
Cdd:PLN02568  508 ATHRTHYSTTHGAYFSGLREANRLLQHYK 536
Amino_oxidase pfam01593
Flavin containing amine oxidoreductase; This family consists of various amine oxidases, ...
45-407 8.83e-37

Flavin containing amine oxidoreductase; This family consists of various amine oxidases, including maze polyamine oxidase (PAO)and various flavin containing monoamine oxidases (MAO). The aligned region includes the flavin binding site of these enzymes. The family also contains phytoene dehydrogenases and related enzymes. In vertebrates MAO plays an important role regulating the intracellular levels of amines via there oxidation; these include various neurotransmitters, neurotoxins and trace amines. In lower eukaryotes such as aspergillus and in bacteria the main role of amine oxidases is to provide a source of ammonium. PAOs in plants, bacteria and protozoa oxidase spermidine and spermine to an aminobutyral, diaminopropane and hydrogen peroxide and are involved in the catabolism of polyamines. Other members of this family include tryptophan 2-monooxygenase, putrescine oxidase, corticosteroid binding proteins and antibacterial glycoproteins.


Pssm-ID: 396255 [Multi-domain]  Cd Length: 446  Bit Score: 139.55  E-value: 8.83e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720398793  45 EQGFtDVTVLEASSHIGGRVQSVRLD-TTFELGATWIHGSHgNPIYQLAEANGLLEETTDGERSVGRIslyskngvacYL 123
Cdd:pfam01593  12 RAGH-DVTVLEARDRVGGRIRTVRDDgFLIELGAMWFHGAQ-PPLLALLKELGLEDRLVLPDPAPFYT----------VL 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720398793 124 TNRGCRIPKDvveeFSDLYNEVynmtQEFFRHGKPVNAES--QNSVGVFTREKVRNRIRDDPDDTEATKRLK-------- 193
Cdd:pfam01593  80 FAGGRRYPGD----FRRVPAGW----EGLLEFGRLLSIPEklRLGLAALASDALDEFDLDDFSLAESLLFLGrrgpgdve 151
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720398793 194 ----LAMIQQYLKVESCeSSSHSIDEVSLSAFGEW-----TEIPGAHHIIPSGFM-RVVELLAEGIPPHVIQLGKPVRCI 263
Cdd:pfam01593 152 vwdrLIDPELFAALPFA-SGAFAGDPSELSAGLALpllwaLLGEGGSLLLPRGGLgALPDALAAQLLGGDVRLNTRVRSI 230
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720398793 264 H------------------------------------------------------------------WDQASAHPRGPEI 277
Cdd:pfam01593 231 DregdgvtvtltdgevieadavivtvplgvlkrilftpplppekarairnlgygpvnkvhlefdrkfWPDLGLLGLLSEL 310
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720398793 278 -------------EPRERYGH--VLSGWI-CGEEALVMERCDDEAVAEICTEMLRQFTGnPNIPKPRRILRSAWGSNPYF 341
Cdd:pfam01593 311 ltglgtafswltfPNRAPPGKglLLLVYVgPGDRARELEGLSDEELLQAVLRDLRKLFG-EEAPEPLRVLVSDWHTDPWP 389
                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1720398793 342 RGSYSYTQVGSSGADVEKLAKPLpytessktAPmQVLFSGEATHRKYYSTTHGALLSGQREAARLI 407
Cdd:pfam01593 390 RGSYSLPQYGPGHDDYRPLARTP--------DP-GLFFAGEHTSTGYPGTVEGAIESGRRAARAVL 446
YobN COG1231
Monoamine oxidase [Amino acid transport and metabolism];
50-408 8.21e-29

Monoamine oxidase [Amino acid transport and metabolism];


Pssm-ID: 440844 [Multi-domain]  Cd Length: 440  Bit Score: 116.94  E-value: 8.21e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720398793  50 DVTVLEASSHIGGRVQSVRLDTT---FELGATWIHGSHGNpIYQLAEANGLleETTDGERSVGRiSLYSKNGVACYLtnr 126
Cdd:COG1231    32 DVTVLEARDRVGGRVWTLRFGDDglyAELGAMRIPPSHTN-LLALARELGL--PLEPFPNENGN-ALLYLGGKRVRA--- 104
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720398793 127 gcRIPKDVVEEFSDLYNE-VYNMTQEFFRHGKPVNAESQNSVGVFtrekvrnrIRDDPDDTEAtkrlkLAMIQQYLKVES 205
Cdd:COG1231   105 --GEIAADLRGVAELLAKlLRALAAALDPWAHPAAELDRESLAEW--------LRRNGASPSA-----RRLLGLLGAGEY 169
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720398793 206 CESSshsiDEVSLSAF---GEWTEIPGAHHIIPSGFMRVVELLAEGIPPHvIQLGKPVRCIHWDQAS---AHPRGPEIE- 278
Cdd:COG1231   170 GADP----DELSLLDLlryAASAGGGAQQFRIVGGMDQLPRALAAELGDR-IRLGAPVTRIRQDGDGvtvTTDDGGTVRa 244
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720398793 279 ---------------------PRER--------YGH-------------------------------------------- 285
Cdd:COG1231   245 davivtvppsvlrriefdpplPAAKraaiqrlpYGAaikvflqfdrpfweedglyggisltdlpirqtwypsngpdggag 324
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720398793 286 VLSGWICGEEALVMERCDDEAVAEICTEMLRQFTGNPnIPKPRRILRSAWGSNPYFRGSYSYTQVGSSGADVEKLAKPLP 365
Cdd:COG1231   325 VLLGYVGGDDARALAALSPEERVAAALEQLARIFGVY-AAEPVDYVSTDWGRDPWSRGAYAAAPPGQLTAAGPALAEPDG 403
                         410       420       430       440
                  ....*....|....*....|....*....|....*....|...
gi 1720398793 366 ytessktapmQVLFSGEATHRKYYSTTHGALLSGQREAARLIE 408
Cdd:COG1231   404 ----------RIHFAGEHTSDEWPGWVEGALESGERAAAEILA 436
PLN02676 PLN02676
polyamine oxidase
25-408 1.25e-18

polyamine oxidase


Pssm-ID: 215362 [Multi-domain]  Cd Length: 487  Bit Score: 87.85  E-value: 1.25e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720398793  25 PRVVVIGAGLAGLAAARALLEQGFTDVTVLEASSHIGGRVQSVRL-DTTFELGATWIHGSHG---NPIYQLAEANGLLEE 100
Cdd:PLN02676   27 PSVIIVGAGMSGISAAKTLSEAGIEDILILEATDRIGGRMRKANFaGVSVELGANWVEGVGGpesNPIWELANKLKLRTF 106
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720398793 101 TTDGERSvgRISLYSKNGVACyltnrgcriPKDVVEEFSDLYNEVYNMTQEFfrhGKPVNAESQNSVGVFTREKVRNRIR 180
Cdd:PLN02676  107 YSDFDNL--SSNIYKQDGGLY---------PKKVVQKSMKVADASDEFGENL---SISLSAKKAVDISILTAQRLFGQVP 172
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720398793 181 DDPddteatkrLKLAMIQQYLKVESCE-----SSSHSIDEVSLSAFGEWTEIPGAhhiiPSGFMRVVELLAEG------- 248
Cdd:PLN02676  173 KTP--------LEMVIDYYNYDYEFAEpprvtSLKNTEPNPTFVDFGEDEYFVAD----PRGYESLVYYLAEQflstksg 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720398793 249 -IPPHVIQLGKPVRCIHW---------DQASAH----------------------------------------------- 271
Cdd:PLN02676  241 kITDPRLKLNKVVREISYskngvtvktEDGSVYrakyvivsvslgvlqsdlikfkpplpdwkieaiyqfdmavytkiflk 320
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720398793 272 ------PRGPEIE----PRERYGH---------------VLSGWICGEEALVMERCDDEAVAEICTEMLRQFTGnPNIPK 326
Cdd:PLN02676  321 fpykfwPSGPGTEfflyAHERRGYypfwqhleneypgsnVLFVTVTDEESRRIEQQPDSETKAEIMEVLRKMFG-PNIPE 399
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720398793 327 PRRILRSAWGSNPYFRGSYSYTQVGSSGADVEKLAKPLPytessktapmQVLFSGEATHRKYYSTTHGALLSGQREAARL 406
Cdd:PLN02676  400 ATDILVPRWWSNRFFKGSYSNWPIGVSRYEFDQIRAPVG----------RVYFTGEHTSEKYNGYVHGAYLAGIDTANDL 469

                  ..
gi 1720398793 407 IE 408
Cdd:PLN02676  470 LE 471
PLN02268 PLN02268
probable polyamine oxidase
51-399 8.32e-17

probable polyamine oxidase


Pssm-ID: 177909 [Multi-domain]  Cd Length: 435  Bit Score: 81.66  E-value: 8.32e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720398793  51 VTVLEASSHIGGRVQSvrlDTTF----ELGATWIHG-SHGNPIYQLAEANGLLEETTDGERSVgrisLYSKNGVACYLTN 125
Cdd:PLN02268   26 VTLLESRDRIGGRVHT---DYSFgfpvDMGASWLHGvCNENPLAPLIGRLGLPLYRTSGDNSV----LYDHDLESYALFD 98
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720398793 126 R-GCRIPKDVVEEFSDLYNEVYNMTqeffrhgkpvnaesqnsvgvftrEKVRNRIRDDPDDTEATKR-------LKLA-- 195
Cdd:PLN02268   99 MdGNQVPQELVTKVGETFERILEET-----------------------EKVRDEHEEDMSLLQAISIvlerhpeLRLEgl 155
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720398793 196 ---MIQQYL-KVESCESSShsIDEVSLSAFGEWTEIPGAHHIIPSGFMRVVELLAEGIPphvIQLGKPVRCIhwdqaSAH 271
Cdd:PLN02268  156 aheVLQWYLcRMEGWFAAD--ADTISLKSWDQEELLEGGHGLMVRGYDPVINTLAKGLD---IRLNHRVTKI-----VRR 225
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720398793 272 PRGPEI-----------------------------EPR------------------------------------------ 280
Cdd:PLN02268  226 YNGVKVtvedgttfvadaaiiavplgvlkaniikfEPElpewkeeaisdlgvgienkialhfdsvfwpnveflgvvapts 305
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720398793 281 ----------ERYGH-VLSGWICGEEALVMERCDDEAVAEICTEMLRQFTgnPNIPKPRRILRSAWGSNPYFRGSYSYTQ 349
Cdd:PLN02268  306 ygcsyflnlhKATGHpVLVYMPAGRLARDIEKLSDEAAANFAMSQLKKML--PDATEPVQYLVSRWGSDPNSLGCYSYDL 383
                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|
gi 1720398793 350 VGSSGADVEKLAKPLPytessktapmQVLFSGEATHRKYYSTTHGALLSG 399
Cdd:PLN02268  384 VGKPHDLYERLRAPVD----------NLFFAGEATSSDFPGSVHGAYSTG 423
PLN02529 PLN02529
lysine-specific histone demethylase 1
284-411 7.15e-16

lysine-specific histone demethylase 1


Pssm-ID: 178144 [Multi-domain]  Cd Length: 738  Bit Score: 79.94  E-value: 7.15e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720398793 284 GHVLSGWICGEEALVMERCDDEAVAEICTEMLRQFTG--NPNIPKPRRILRSAWGSNPYFRGSYSYTQVGSSGADVEKLA 361
Cdd:PLN02529  479 GPALVALVAGEAAQRFENTDPSTLLHRVLSVLRGIYNpkGINVPDPIQTICTRWGSDPLSYGSYSHVRVQSSGSDYDILA 558
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 1720398793 362 KplpytesskTAPMQVLFSGEATHRKYYSTTHGALLSGQREAARLIEMYR 411
Cdd:PLN02529  559 E---------SVSGRLFFAGEATTRQYPATMHGAFLSGLREASRILHVAR 599
PLN02976 PLN02976
amine oxidase
46-411 1.32e-15

amine oxidase


Pssm-ID: 215527 [Multi-domain]  Cd Length: 1713  Bit Score: 79.14  E-value: 1.32e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720398793   46 QGFTdVTVLEASSHIGGRVQSVR--LDTTFELGATWIHGshgnpiyqlaeanglLEETTDGERSVGRISLY-SKNGVACY 122
Cdd:PLN02976   715 QGFS-VTVLEARSRIGGRVYTDRssLSVPVDLGASIITG---------------VEADVATERRPDPSSLIcAQLGLELT 778
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720398793  123 LTNRGC---------RIPKDVVEEFSDLYNEVYN-MTQEFFRHGKPVNAESQNSVGVFTREKVR-NRIRDDPDDTEATKR 191
Cdd:PLN02976   779 VLNSDCplydvvtgeKVPADLDEALEAEYNSLLDdMVLLVAQKGEHAMKMSLEDGLEYALKRRRmPRPGVDIDETELGNA 858
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720398793  192 LKLAMIQQYLKVE--SCESSS------------------H-------SIDEVSL---------SAFGewteipGAHHIIP 235
Cdd:PLN02976   859 ADDLYDSASTGVDggHCEKESkedvlsplerrvmnwhfaHleygcaaLLKEVSLpywnqddvyGGFG------GAHCMIK 932
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720398793  236 SGFMRVVELLAEGIPPHVIQ--------------------------------LGK------PVRCI------------HW 265
Cdd:PLN02976   933 GGYSNVVESLAEGLDIHLNHvvtdvsygskdagasgssrkkvkvstsngsefLGDavlitvPLGCLkaetikfspplpDW 1012
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720398793  266 DQASAHPRG-----------PEI-------------EPRERYGH--------------VLSGWICGEEALVMERCDDEAV 307
Cdd:PLN02976  1013 KYSSIQRLGfgvlnkvvlefPEVfwddsvdyfgataEETDLRGQcfmfwnvkktvgapVLIALVVGKAAIDGQSMSSSDH 1092
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720398793  308 AEICTEMLRQFTGNPNIPKPRRILRSAWGSNPYFRGSYSYTQVGSSGADVEKLAKPLpytESSktapmqVLFSGEATHRK 387
Cdd:PLN02976  1093 VNHALMVLRKLFGEALVPDPVASVVTDWGRDPFSYGAYSYVAIGASGEDYDILGRPV---ENC------LFFAGEATCKE 1163
                          490       500
                   ....*....|....*....|....
gi 1720398793  388 YYSTTHGALLSGQREAARLIEMYR 411
Cdd:PLN02976  1164 HPDTVGGAMMSGLREAVRIIDILN 1187
PLN02328 PLN02328
lysine-specific histone demethylase 1 homolog
324-411 2.80e-15

lysine-specific histone demethylase 1 homolog


Pssm-ID: 215187 [Multi-domain]  Cd Length: 808  Bit Score: 78.11  E-value: 2.80e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720398793 324 IPKPRRILRSAWGSNPYFRGSYSYTQVGSSGADVEKLAKPLpytessktAPMQVLFSGEATHRKYYSTTHGALLSGQREA 403
Cdd:PLN02328  601 VPDPVQAVCTRWGKDCFTYGSYSYVAVGSSGDDYDILAESV--------GDGRVFFAGEATNKQYPATMHGAFLSGMREA 672

                  ....*...
gi 1720398793 404 ARLIEMYR 411
Cdd:PLN02328  673 ANILRVAR 680
PLN03000 PLN03000
amine oxidase
323-406 4.06e-14

amine oxidase


Pssm-ID: 178578 [Multi-domain]  Cd Length: 881  Bit Score: 74.29  E-value: 4.06e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1720398793 323 NIPKPRRILRSAWGSNPYFRGSYSYTQVGSSGADVEKLAKplpytessKTAPMQVLFSGEATHRKYYSTTHGALLSGQRE 402
Cdd:PLN03000  544 NVPDPLQTVCTRWGGDPFSLGSYSNVAVGASGDDYDILAE--------SVGDGRLFFAGEATTRRYPATMHGAFVTGLRE 615

                  ....
gi 1720398793 403 AARL 406
Cdd:PLN03000  616 AANM 619
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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