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Conserved domains on  [gi|1907181402|ref|XP_036009011|]
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tsukushi isoform X1 [Mus musculus]

Protein Classification

leucine-rich repeat domain-containing protein( domain architecture ID 11469232)

leucine-rich repeat (LRR) domain-containing protein may participate in protein-protein interactions

CATH:  3.80.10.10
Gene Ontology:  GO:0005515
PubMed:  11751054|7583641

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
85-300 1.57e-18

Leucine-rich repeat (LRR) protein [Transcription];


:

Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 86.14  E-value: 1.57e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907181402  85 TTLAGLDLSYNLLTSImPSAFSRLRYLESLDLSHNGLAALPAEIFTSSPLSDINLSHNRLREVSISAftthSQGRAL-HV 163
Cdd:COG4886   113 TNLESLDLSGNQLTDL-PEELANLTNLKELDLSNNQLTDLPEPLGNLTNLKSLDLSNNQLTDLPEEL----GNLTNLkEL 187

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907181402 164 DLSHNLIhrllphparASLPAP-----TIQSLNLSWNRFRAVPD-LRDLP-LRYLSLDGNPLATInpDAFMGLAGLTHLS 236
Cdd:COG4886   188 DLSNNQI---------TDLPEPlgnltNLEELDLSGNQLTDLPEpLANLTnLETLDLSNNQLTDL--PELGNLTNLEELD 256

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1907181402 237 LASLQgILHLPPHGfrELPGLQVLDLSGNP--KLKWAGAEVFSGLGLLQELDLSGSSLVPLPEMLL 300
Cdd:COG4886   257 LSNNQ-LTDLPPLA--NLTNLKTLDLSNNQltDLKLKELELLLGLNSLLLLLLLLNLLELLILLLL 319
 
Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
85-300 1.57e-18

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 86.14  E-value: 1.57e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907181402  85 TTLAGLDLSYNLLTSImPSAFSRLRYLESLDLSHNGLAALPAEIFTSSPLSDINLSHNRLREVSISAftthSQGRAL-HV 163
Cdd:COG4886   113 TNLESLDLSGNQLTDL-PEELANLTNLKELDLSNNQLTDLPEPLGNLTNLKSLDLSNNQLTDLPEEL----GNLTNLkEL 187

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907181402 164 DLSHNLIhrllphparASLPAP-----TIQSLNLSWNRFRAVPD-LRDLP-LRYLSLDGNPLATInpDAFMGLAGLTHLS 236
Cdd:COG4886   188 DLSNNQI---------TDLPEPlgnltNLEELDLSGNQLTDLPEpLANLTnLETLDLSNNQLTDL--PELGNLTNLEELD 256

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1907181402 237 LASLQgILHLPPHGfrELPGLQVLDLSGNP--KLKWAGAEVFSGLGLLQELDLSGSSLVPLPEMLL 300
Cdd:COG4886   257 LSNNQ-LTDLPPLA--NLTNLKTLDLSNNQltDLKLKELELLLGLNSLLLLLLLLNLLELLILLLL 319
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 64-175 5.65e-09

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 57.55  E-value: 5.65e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907181402  64 LDLSSNRLETVNESVLAGpgYTTLAGLDLSYNLLTSIMPSAFSRLRYLESLDLSHNGLAALPAEIFTSSP-LSDINLSHN 142
Cdd:PLN00113  480 LDLSRNQFSGAVPRKLGS--LSELMQLKLSENKLSGEIPDELSSCKKLVSLDLSHNQLSGQIPASFSEMPvLSQLDLSQN 557

                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 1907181402 143 RLrevsiSAFTTHSQGRA---LHVDLSHNLIHRLLP 175
Cdd:PLN00113  558 QL-----SGEIPKNLGNVeslVQVNISHNHLHGSLP 588
LRR_8 pfam13855
Leucine rich repeat;
208-266 5.81e-09

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 51.76  E-value: 5.81e-09
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1907181402 208 LRYLSLDGNPLATINPDAFMGLAGLTHLSLASLQgILHLPPHGFRELPGLQVLDLSGNP 266
Cdd:pfam13855   3 LRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNL-LTTLSPGAFSGLPSLRYLDLSGNR 60
LRR_RI cd00116
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ...
 60-275 7.06e-04

Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).


Pssm-ID: 238064 [Multi-domain]  Cd Length: 319  Bit Score: 41.19  E-value: 7.06e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907181402  60 DTAHLDLSSNRLETVNESV-LAGPGYTTLAGL---DLSYNLLTSIMPSAFSRLR---YLESLDLSHNGLAALPAEIFT-- 130
Cdd:cd00116    52 SLKELCLSLNETGRIPRGLqSLLQGLTKGCGLqelDLSDNALGPDGCGVLESLLrssSLQELKLNNNGLGDRGLRLLAkg 131

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907181402 131 ----SSPLSDINLSHNRL-REVSISAFTTHSQGRALH-VDLSHNLI-HRLLPHPARASLPAPTIQSLNLSWNRFR----- 198
Cdd:cd00116   132 lkdlPPALEKLVLGRNRLeGASCEALAKALRANRDLKeLNLANNGIgDAGIRALAEGLKANCNLEVLDLNNNGLTdegas 211

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907181402 199 ----AVPDLRDLplRYLSLDGNPL-----ATINPDAFMGLAGLTHLSLASLqgilHLPPHGFREL-------PGLQVLDL 262
Cdd:cd00116   212 alaeTLASLKSL--EVLNLGDNNLtdagaAALASALLSPNISLLTLSLSCN----DITDDGAKDLaevlaekESLLELDL 285

                         250
                  ....*....|...
gi 1907181402 263 SGNpKLKWAGAEV 275
Cdd:cd00116   286 RGN-KFGEEGAQL 297
 
Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
85-300 1.57e-18

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 86.14  E-value: 1.57e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907181402  85 TTLAGLDLSYNLLTSImPSAFSRLRYLESLDLSHNGLAALPAEIFTSSPLSDINLSHNRLREVSISAftthSQGRAL-HV 163
Cdd:COG4886   113 TNLESLDLSGNQLTDL-PEELANLTNLKELDLSNNQLTDLPEPLGNLTNLKSLDLSNNQLTDLPEEL----GNLTNLkEL 187

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907181402 164 DLSHNLIhrllphparASLPAP-----TIQSLNLSWNRFRAVPD-LRDLP-LRYLSLDGNPLATInpDAFMGLAGLTHLS 236
Cdd:COG4886   188 DLSNNQI---------TDLPEPlgnltNLEELDLSGNQLTDLPEpLANLTnLETLDLSNNQLTDL--PELGNLTNLEELD 256

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1907181402 237 LASLQgILHLPPHGfrELPGLQVLDLSGNP--KLKWAGAEVFSGLGLLQELDLSGSSLVPLPEMLL 300
Cdd:COG4886   257 LSNNQ-LTDLPPLA--NLTNLKTLDLSNNQltDLKLKELELLLGLNSLLLLLLLLNLLELLILLLL 319
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
34-311 1.69e-15

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 76.90  E-value: 1.69e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907181402  34 LFDSFSLIRVDCSSLGPHIVPVPIPLDTAHLDLSSNRLETVNESVLAGPGYTTLAGLDLSYNLLTSIMPSAFSRLRYLES 113
Cdd:COG4886    21 LTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTE 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907181402 114 LDLSHNglaalpAEIFTSSPLSDINLSHNRLRE--VSISAFTthsqgrAL-HVDLSHNLIHRLlpHPARASLPAptIQSL 190
Cdd:COG4886   101 LDLSGN------EELSNLTNLESLDLSGNQLTDlpEELANLT------NLkELDLSNNQLTDL--PEPLGNLTN--LKSL 164

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907181402 191 NLSWNRFRAVPD-LRDLP-LRYLSLDGNPLATInPDAFMGLAGLTHLSLASLQgILHLPPhGFRELPGLQVLDLSGNP-- 266
Cdd:COG4886   165 DLSNNQLTDLPEeLGNLTnLKELDLSNNQITDL-PEPLGNLTNLEELDLSGNQ-LTDLPE-PLANLTNLETLDLSNNQlt 241

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*
gi 1907181402 267 KLKWagaevFSGLGLLQELDLSGSSLVPLPEmlLHHLPALQSVSV 311
Cdd:COG4886   242 DLPE-----LGNLTNLEELDLSNNQLTDLPP--LANLTNLKTLDL 279
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
63-268 8.79e-11

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 62.64  E-value: 8.79e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907181402  63 HLDLSSNRLETVNESvLAGPgyTTLAGLDLSYNLLTSImPSAFSRLRYLESLDLSHNGLAALPaEIFTSSPLSDINLSHN 142
Cdd:COG4886   186 ELDLSNNQITDLPEP-LGNL--TNLEELDLSGNQLTDL-PEPLANLTNLETLDLSNNQLTDLP-ELGNLTNLEELDLSNN 260

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907181402 143 RLREVSISAFTTHSQgralHVDLSHNLIHRL-LPHPARASLPAPTIQSLNLSWNRFRAVPDLRDLPLRYLSLDGNPLATI 221
Cdd:COG4886   261 QLTDLPPLANLTNLK----TLDLSNNQLTDLkLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVT 336

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 1907181402 222 NPDAFMGLAGLTHLSLASLQGILHLPPHGFRELPGLQVLDLSGNPKL 268
Cdd:COG4886   337 LTTLALSLSLLALLTLLLLLNLLSLLLTLLLTLGLLGLLEATLLTLA 383
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 64-175 5.65e-09

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 57.55  E-value: 5.65e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907181402  64 LDLSSNRLETVNESVLAGpgYTTLAGLDLSYNLLTSIMPSAFSRLRYLESLDLSHNGLAALPAEIFTSSP-LSDINLSHN 142
Cdd:PLN00113  480 LDLSRNQFSGAVPRKLGS--LSELMQLKLSENKLSGEIPDELSSCKKLVSLDLSHNQLSGQIPASFSEMPvLSQLDLSQN 557

                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 1907181402 143 RLrevsiSAFTTHSQGRA---LHVDLSHNLIHRLLP 175
Cdd:PLN00113  558 QL-----SGEIPKNLGNVeslVQVNISHNHLHGSLP 588
LRR_8 pfam13855
Leucine rich repeat;
208-266 5.81e-09

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 51.76  E-value: 5.81e-09
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1907181402 208 LRYLSLDGNPLATINPDAFMGLAGLTHLSLASLQgILHLPPHGFRELPGLQVLDLSGNP 266
Cdd:pfam13855   3 LRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNL-LTTLSPGAFSGLPSLRYLDLSGNR 60
LRR_8 pfam13855
Leucine rich repeat;
64-121 6.01e-08

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 49.06  E-value: 6.01e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1907181402  64 LDLSSNRLETVNESVLAGPgyTTLAGLDLSYNLLTSIMPSAFSRLRYLESLDLSHNGL 121
Cdd:pfam13855   6 LDLSNNRLTSLDDGAFKGL--SNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 64-265 1.70e-06

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 49.85  E-value: 1.70e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907181402  64 LDLSSNRLETVNESVLAGPGYttLAGLDLSYNLLTSIMPSAFSRLRYLESLDLSHNGLAA-LPAEiFTSSPLSD-INLSH 141
Cdd:PLN00113  361 LDLSTNNLTGEIPEGLCSSGN--LFKLILFSNSLEGEIPKSLGACRSLRRVRLQDNSFSGeLPSE-FTKLPLVYfLDISN 437

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907181402 142 NRLREVSISAFTTHSQGRALhvDLSHNLIHRLLPHPARASlpapTIQSLNLSWNRFR-AVPD-LRDLP-LRYLSLDGNPL 218
Cdd:PLN00113  438 NNLQGRINSRKWDMPSLQML--SLARNKFFGGLPDSFGSK----RLENLDLSRNQFSgAVPRkLGSLSeLMQLKLSENKL 511

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 1907181402 219 ATINPDAFMGLAGLTHLSLASLQGILHLPPhGFRELPGLQVLDLSGN 265
Cdd:PLN00113  512 SGEIPDELSSCKKLVSLDLSHNQLSGQIPA-SFSEMPVLSQLDLSQN 557
PRK15370 PRK15370
type III secretion system effector E3 ubiquitin transferase SlrP;
48-266 2.62e-06

type III secretion system effector E3 ubiquitin transferase SlrP;


Pssm-ID: 185268 [Multi-domain]  Cd Length: 754  Bit Score: 49.31  E-value: 2.62e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907181402  48 LGPHIVPVPIPLDTAHLDLSSNRLET-------------VNESVLAGPGYT---TLAGLDLSYNLLTSI---MPSAfsrl 108
Cdd:PRK15370  188 LGLTTIPACIPEQITTLILDNNELKSlpenlqgniktlyANSNQLTSIPATlpdTIQEMELSINRITELperLPSA---- 263

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907181402 109 ryLESLDLSHNGLAALPAEIftSSPLSDINLSHNrlrevSISAFTTHSQGRALHVDLSHNLIHRL---LP---------H 176
Cdd:PRK15370  264 --LQSLDLFHNKISCLPENL--PEELRYLSVYDN-----SIRTLPAHLPSGITHLNVQSNSLTALpetLPpglktleagE 334

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907181402 177 PARASLPA---PTIQSLNLSWNRFRAVPDLRDLPLRYLSLDGNPLATInPDAFMglAGLTHLSlASLQGILHLP---PHG 250
Cdd:PRK15370  335 NALTSLPAslpPELQVLDVSKNQITVLPETLPPTITTLDVSRNALTNL-PENLP--AALQIMQ-ASRNNLVRLPeslPHF 410

                         250
                  ....*....|....*.
gi 1907181402 251 FRELPGLQVLDLSGNP 266
Cdd:PRK15370  411 RGEGPQPTRIIVEYNP 426
LRR_8 pfam13855
Leucine rich repeat;
231-292 7.42e-06

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 42.90  E-value: 7.42e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1907181402 231 GLTHLSLASlQGILHLPPHGFRELPGLQVLDLSGNpKLKWAGAEVFSGLGLLQELDLSGSSL 292
Cdd:pfam13855   2 NLRSLDLSN-NRLTSLDDGAFKGLSNLKVLDLSNN-LLTTLSPGAFSGLPSLRYLDLSGNRL 61
LRR_8 pfam13855
Leucine rich repeat;
185-239 9.97e-06

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 42.51  E-value: 9.97e-06
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1907181402 185 PTIQSLNLSWNRFRAVPD--LRDLP-LRYLSLDGNPLATINPDAFMGLAGLTHLSLAS 239
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLDDgaFKGLSnLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSG 58
PRK15370 PRK15370
type III secretion system effector E3 ubiquitin transferase SlrP;
113-338 1.01e-05

type III secretion system effector E3 ubiquitin transferase SlrP;


Pssm-ID: 185268 [Multi-domain]  Cd Length: 754  Bit Score: 47.38  E-value: 1.01e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907181402 113 SLDLSHNGLAALPAEIftSSPLSDINLSHNRLREVSISAFTTHSQgralhVDLSHNLIHRLLPHparasLPApTIQSLNL 192
Cdd:PRK15370  203 TLILDNNELKSLPENL--QGNIKTLYANSNQLTSIPATLPDTIQE-----MELSINRITELPER-----LPS-ALQSLDL 269

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907181402 193 SWNRFRAVPDlrDLP--LRYLSLDGNPLATInPDAFMglAGLTHLSLASlQGILHLP---PHGFREL------------- 254
Cdd:PRK15370  270 FHNKISCLPE--NLPeeLRYLSVYDNSIRTL-PAHLP--SGITHLNVQS-NSLTALPetlPPGLKTLeagenaltslpas 343

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907181402 255 --PGLQVLDLSGN-----PKlkwagaevfSGLGLLQELDLSGSSLVPLPEmllhHLPALQSVSVGQDVQCRRLVREGAYH 327
Cdd:PRK15370  344 lpPELQVLDVSKNqitvlPE---------TLPPTITTLDVSRNALTNLPE----NLPAALQIMQASRNNLVRLPESLPHF 410

                         250
                  ....*....|.
gi 1907181402 328 RQPGSSPKVVL 338
Cdd:PRK15370  411 RGEGPQPTRII 421
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 64-299 1.52e-04

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 43.68  E-value: 1.52e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907181402  64 LDLSSNRL--ETVNESVLagpgYTTLAGLDLSYNLLTSIMPSAFSRLRYLESLDLSHNGLAA-LPAEIFTSSPLSDINLS 140
Cdd:PLN00113  145 LDLSNNMLsgEIPNDIGS----FSSLKVLDLGGNVLVGKIPNSLTNLTSLEFLTLASNQLVGqIPRELGQMKSLKWIYLG 220

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907181402 141 HNRLR---EVSISAFTTHSqgralHVDLSHNlihrllphparaSLPAPTIQSLNlswnrfravpDLRDlpLRYLSLDGNP 217
Cdd:PLN00113  221 YNNLSgeiPYEIGGLTSLN-----HLDLVYN------------NLTGPIPSSLG----------NLKN--LQYLFLYQNK 271

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907181402 218 LATINPDAFMGLAGLTHLSLA--SLQG-------------ILHL--------PPHGFRELPGLQVLDLSGNpklKWAGaE 274
Cdd:PLN00113  272 LSGPIPPSIFSLQKLISLDLSdnSLSGeipelviqlqnleILHLfsnnftgkIPVALTSLPRLQVLQLWSN---KFSG-E 347

                         250       260
                  ....*....|....*....|....*....
gi 1907181402 275 VFSGLGL---LQELDLSGSSLV-PLPEML 299
Cdd:PLN00113  348 IPKNLGKhnnLTVLDLSTNNLTgEIPEGL 376
LRR_8 pfam13855
Leucine rich repeat;
109-170 2.50e-04

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 38.66  E-value: 2.50e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1907181402 109 RYLESLDLSHNGLAALPAEIFTS-SPLSDINLSHNRLREVSISAFtthSQGRAL-HVDLSHNLI 170
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLDDGAFKGlSNLKVLDLSNNLLTTLSPGAF---SGLPSLrYLDLSGNRL 61
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 87-247 3.16e-04

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 42.53  E-value: 3.16e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907181402  87 LAGLDLSYNLLTSIMPSAFSRLRYLESLDLSHNGLAA-LPAEIF-TSSPLSDINLSHNRLR----EVSISAFTThsqgra 160
Cdd:PLN00113   71 VVSIDLSGKNISGKISSAIFRLPYIQTINLSNNQLSGpIPDDIFtTSSSLRYLNLSNNNFTgsipRGSIPNLET------ 144

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907181402 161 lhVDLSHNLIHRLLPhparaslpaptiQSLNLSWNrfravpdlrdlpLRYLSLDGNPLATINPDAFMGLAGLTHLSLASL 240
Cdd:PLN00113  145 --LDLSNNMLSGEIP------------NDIGSFSS------------LKVLDLGGNVLVGKIPNSLTNLTSLEFLTLASN 198


                  ....*..
gi 1907181402 241 QGILHLP 247
Cdd:PLN00113  199 QLVGQIP 205
LRR_RI cd00116
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ...
 60-275 7.06e-04

Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).


Pssm-ID: 238064 [Multi-domain]  Cd Length: 319  Bit Score: 41.19  E-value: 7.06e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907181402  60 DTAHLDLSSNRLETVNESV-LAGPGYTTLAGL---DLSYNLLTSIMPSAFSRLR---YLESLDLSHNGLAALPAEIFT-- 130
Cdd:cd00116    52 SLKELCLSLNETGRIPRGLqSLLQGLTKGCGLqelDLSDNALGPDGCGVLESLLrssSLQELKLNNNGLGDRGLRLLAkg 131

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907181402 131 ----SSPLSDINLSHNRL-REVSISAFTTHSQGRALH-VDLSHNLI-HRLLPHPARASLPAPTIQSLNLSWNRFR----- 198
Cdd:cd00116   132 lkdlPPALEKLVLGRNRLeGASCEALAKALRANRDLKeLNLANNGIgDAGIRALAEGLKANCNLEVLDLNNNGLTdegas 211

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907181402 199 ----AVPDLRDLplRYLSLDGNPL-----ATINPDAFMGLAGLTHLSLASLqgilHLPPHGFREL-------PGLQVLDL 262
Cdd:cd00116   212 alaeTLASLKSL--EVLNLGDNNLtdagaAALASALLSPNISLLTLSLSCN----DITDDGAKDLaevlaekESLLELDL 285

                         250
                  ....*....|...
gi 1907181402 263 SGNpKLKWAGAEV 275
Cdd:cd00116   286 RGN-KFGEEGAQL 297
PLN03150 PLN03150
hypothetical protein; Provisional
 89-144 8.78e-04

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 41.34  E-value: 8.78e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 1907181402  89 GLDLSYNLLTSIMPSAFSRLRYLESLDLSHNGL-AALPAEIFTSSPLSDINLSHNRL 144
Cdd:PLN03150  422 GLGLDNQGLRGFIPNDISKLRHLQSINLSGNSIrGNIPPSLGSITSLEVLDLSYNSF 478
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
63-234 1.01e-03

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 40.69  E-value: 1.01e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907181402  63 HLDLSSNRLETVNEsvLAGPgyTTLAGLDLSYNLLTSImpSAFSRLRYLESLDLSHNGLAALPAEIFTSSPLSDINLSHN 142
Cdd:COG4886   232 TLDLSNNQLTDLPE--LGNL--TNLEELDLSNNQLTDL--PPLANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLL 305

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907181402 143 RLREVSISAFTTHSQGRALHVDLSHNLIHRLLPHPARASLPAPTIQSLNLSWNRFRAVPDLRDLPLRYLSLDGNPLATIN 222
Cdd:COG4886   306 LLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLLSLLLTLLLTLGLLGLLEATLLTLALL 385

                         170
                  ....*....|..
gi 1907181402 223 PDAFMGLAGLTH 234
Cdd:COG4886   386 LLTLLLLLLTTT 397
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 90-215 1.50e-03

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 40.60  E-value: 1.50e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907181402  90 LDLSYNLLTSIMPSAFSRLRYLESLDLSHNGLAALPAEIFTSSPLSDINLSHNRLREVSISAFTTHSQgrALHVDLSHNL 169
Cdd:PLN00113  433 LDISNNNLQGRINSRKWDMPSLQMLSLARNKFFGGLPDSFGSKRLENLDLSRNQFSGAVPRKLGSLSE--LMQLKLSENK 510

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1907181402 170 IHRLLPHPARAslpAPTIQSLNLSWNR--------FRAVPDLRDLPLRYLSLDG 215
Cdd:PLN00113  511 LSGEIPDELSS---CKKLVSLDLSHNQlsgqipasFSEMPVLSQLDLSQNQLSG 561
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 83-265 1.58e-03

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 40.60  E-value: 1.58e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907181402  83 GYTTLAGLDLSYNLLTSIMPSAFSRLRYLESLDLSHNGLAA-LPAEIFTSSPLSDINLSHNRLREvSISAFTTHSQG-RA 160
Cdd:PLN00113  234 GLTSLNHLDLVYNNLTGPIPSSLGNLKNLQYLFLYQNKLSGpIPPSIFSLQKLISLDLSDNSLSG-EIPELVIQLQNlEI 312

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907181402 161 LHVdLSHNLIHRLlphP-ARASLpaPTIQSLNLSWNRFRA-VPdlRDL----PLRYLSLDGNPLATINPDAFMGLAGLTH 234
Cdd:PLN00113  313 LHL-FSNNFTGKI---PvALTSL--PRLQVLQLWSNKFSGeIP--KNLgkhnNLTVLDLSTNNLTGEIPEGLCSSGNLFK 384

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1907181402 235 LSL--ASLQGilHLP-----------------------PHGFRELPGLQVLDLSGN 265
Cdd:PLN00113  385 LILfsNSLEG--EIPkslgacrslrrvrlqdnsfsgelPSEFTKLPLVYFLDISNN 438
LRR_8 pfam13855
Leucine rich repeat;
255-308 2.82e-03

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 35.58  E-value: 2.82e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 1907181402 255 PGLQVLDLSGNpKLKWAGAEVFSGLGLLQELDLSGSSLVPLPEMLLHHLPALQS 308
Cdd:pfam13855   1 PNLRSLDLSNN-RLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRY 53
LRR_8 pfam13855
Leucine rich repeat;
134-197 5.84e-03

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 34.81  E-value: 5.84e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1907181402 134 LSDINLSHNRLREVSISAFTTHSQGRALhvDLSHNLIHRLLPHpARASLPAptIQSLNLSWNRF 197
Cdd:pfam13855   3 LRSLDLSNNRLTSLDDGAFKGLSNLKVL--DLSNNLLTTLSPG-AFSGLPS--LRYLDLSGNRL 61
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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