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Conserved domains on  [gi|1907070408|ref|XP_036009584|]
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cilia- and flagella-associated protein 45 isoform X1 [Mus musculus]

Protein Classification

trichohyalin-plectin-homology domain domain-containing protein( domain architecture ID 12159040)

trichohyalin-plectin-homology domain (TPH) domain-containing protein similar to meiosis-specific nuclear structural protein 1, trichoplein keratin filament-binding protein, and cilia- and flagella-associated proteins

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TPH pfam13868
Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of ...
 155-495 9.31e-66

Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of eukaryotic proteins. Trichoplein or mitostatin, was first defined as a meiosis-specific nuclear structural protein. It has since been linked with mitochondrial movement. It is associated with the mitochondrial outer membrane, and over-expression leads to reduction in mitochondrial motility whereas lack of it enhances mitochondrial movement. The activity appears to be mediated through binding the mitochondria to the actin intermediate filaments (IFs). The family is in the trichohyalin-plectin-homology domain.


:

Pssm-ID: 464007 [Multi-domain]  Cd Length: 341  Bit Score: 216.32  E-value: 9.31e-66
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408 155 RMEQEEELKDMSKIILNAKCHAIRDAQILEKQQIQKELDEEERRLDHMMEIDRRESLQRQEDRERKRREERVRGKRHIVE 234
Cdd:pfam13868   1 LRENSDELRELNSKLLAAKCNKERDAQIAEKKRIKAEEKEEERRLDEMMEEERERALEEEEEKEEERKEERKRYRQELEE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408 235 QIKKNEEERSLQAEHREQEKEQMLAYLDRLQEEDLQDLERRHQEKLKMQAEIKRINDENQRQKAEMLAQERLADQMVMEF 314
Cdd:pfam13868  81 QIEEREQKRQEEYEEKLQEREQMDEIVERIQEEDQAEAEEKLEKQRQLREEIDEFNEEQAEWKELEKEEEREEDERILEY 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408 315 TKKKMAREAEYEAEQEKIRREKEKEIARLRALQEKAQDYQAEQDALRAKRNQEVADREWRRKEKENAQKKIETEEKLRKS 394
Cdd:pfam13868 161 LKEKAEREEEREAEREEIEEEKEREIARLRAQQEKAQDEKAERDELRAKLYQEEQERKERQKEREEAEKKARQRQELQQA 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408 395 RLEQVAFKEHTLAVQVQRDRDEFERILRAQREQIEREKQEQEKKAKGCLQHANELRRQVRENQQKHVQNRLATFEEGRRL 474
Cdd:pfam13868 241 REEQIELKERRLAEEAEREEEEFERMLRKQAEDEEIEQEEAEKRRMKRLEHRRELEKQIEEREEQRAAEREEELEEGERL 320

                         330       340
                  ....*....|....*....|.
gi 1907070408 475 KEEAEKRRERIEDIKKQKLEE 495
Cdd:pfam13868 321 REEEAERRERIEEERQKKLKE 341
 
Name Accession Description Interval E-value
TPH pfam13868
Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of ...
 155-495 9.31e-66

Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of eukaryotic proteins. Trichoplein or mitostatin, was first defined as a meiosis-specific nuclear structural protein. It has since been linked with mitochondrial movement. It is associated with the mitochondrial outer membrane, and over-expression leads to reduction in mitochondrial motility whereas lack of it enhances mitochondrial movement. The activity appears to be mediated through binding the mitochondria to the actin intermediate filaments (IFs). The family is in the trichohyalin-plectin-homology domain.


Pssm-ID: 464007 [Multi-domain]  Cd Length: 341  Bit Score: 216.32  E-value: 9.31e-66
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408 155 RMEQEEELKDMSKIILNAKCHAIRDAQILEKQQIQKELDEEERRLDHMMEIDRRESLQRQEDRERKRREERVRGKRHIVE 234
Cdd:pfam13868   1 LRENSDELRELNSKLLAAKCNKERDAQIAEKKRIKAEEKEEERRLDEMMEEERERALEEEEEKEEERKEERKRYRQELEE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408 235 QIKKNEEERSLQAEHREQEKEQMLAYLDRLQEEDLQDLERRHQEKLKMQAEIKRINDENQRQKAEMLAQERLADQMVMEF 314
Cdd:pfam13868  81 QIEEREQKRQEEYEEKLQEREQMDEIVERIQEEDQAEAEEKLEKQRQLREEIDEFNEEQAEWKELEKEEEREEDERILEY 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408 315 TKKKMAREAEYEAEQEKIRREKEKEIARLRALQEKAQDYQAEQDALRAKRNQEVADREWRRKEKENAQKKIETEEKLRKS 394
Cdd:pfam13868 161 LKEKAEREEEREAEREEIEEEKEREIARLRAQQEKAQDEKAERDELRAKLYQEEQERKERQKEREEAEKKARQRQELQQA 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408 395 RLEQVAFKEHTLAVQVQRDRDEFERILRAQREQIEREKQEQEKKAKGCLQHANELRRQVRENQQKHVQNRLATFEEGRRL 474
Cdd:pfam13868 241 REEQIELKERRLAEEAEREEEEFERMLRKQAEDEEIEQEEAEKRRMKRLEHRRELEKQIEEREEQRAAEREEELEEGERL 320

                         330       340
                  ....*....|....*....|.
gi 1907070408 475 KEEAEKRRERIEDIKKQKLEE 495
Cdd:pfam13868 321 REEEAERRERIEEERQKKLKE 341
PTZ00121 PTZ00121
MAEBL; Provisional
 81-522 4.21e-10

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 62.85  E-value: 4.21e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408   81 ERIKWASQVLTKEELNAREQALKKEKEGILEAVTIRKKIMKQKEMTWNNNKKLSDLEEVARERAQNLLQRADKLRMEQEE 160
Cdd:PTZ00121  1275 EEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEA 1354

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408  161 ELKDMSKIILNAKCHAIRDAQILEKQQIQKELDEEERRLDHMMEIDRRESLQRQEDRERKRREERVRGKRHIVEQIKKNE 240
Cdd:PTZ00121  1355 AADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKAD 1434

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408  241 EERSLQAEHREQEKEQMLAYLDRLQEEDLQDLE-RRHQEKLKMQAEIKRINDENQRQKAEMLAQERLADQMVMEFTKKKM 319
Cdd:PTZ00121  1435 EAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEeAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADE 1514

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408  320 AREAEYEAEQEKIRREKEKEIARLRALQEKAQDYQAEQDALRAKRNQEVADREWRRKEKENAQKKIETEEKLRKSRLEQV 399
Cdd:PTZ00121  1515 AKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARI 1594

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408  400 AFKEHTLAVQVQRDRDEFERILRAQREQIEREKQEQEKKAKGCLQH--------ANELRRQVRENQQKHVQNRLATFEEG 471
Cdd:PTZ00121  1595 EEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKkeaeekkkAEELKKAEEENKIKAAEEAKKAEEDK 1674

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1907070408  472 RR---LKEEAEKRRERIEDIKKQKLEELRATGLPEKYCIEVERKANILPATSVN 522
Cdd:PTZ00121  1675 KKaeeAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEEN 1728
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 241-495 7.53e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 58.41  E-value: 7.53e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408 241 EERSLQAEHREQEKEQMLAYLDRLQEEDLQDLERRHQEKLKMQAEIKRINDENQRQKAEMLAQERLADQMVMEFTKKKMA 320
Cdd:COG1196   235 RELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRREL 314

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408 321 REAEYEAEQE--KIRREKEKEIARLRALQEKAQDYQAEQDALRAKRNQEVADREWRRKEKENAQKKIETEEKLRKSRLEQ 398
Cdd:COG1196   315 EERLEELEEElaELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRA 394

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408 399 VAFKEHTLAVQVQRDRDEFERILRAQREQIEREKQEQEKKAKgcLQHANELRRQVRENQQKHVQNRLATFEEGRRLKEEA 478
Cdd:COG1196   395 AAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEE--EEEEEEALEEAAEEEAELEEEEEALLELLAELLEEA 472

                         250
                  ....*....|....*..
gi 1907070408 479 EKRRERIEDIKKQKLEE 495
Cdd:COG1196   473 ALLEAALAELLEELAEA 489
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 140-459 1.15e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 45.05  E-value: 1.15e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408  140 ARERAQNLLQRADKLRmEQEEELKDMSkiilnAKCHAIRDAQI-LEKQQIQKELDEEERRLDHMMEIDRRESLQRQEDRE 218
Cdd:TIGR02168  665 SAKTNSSILERRREIE-ELEEKIEELE-----EKIAELEKALAeLRKELEELEEELEQLRKELEELSRQISALRKDLARL 738

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408  219 RKRREERVRGKRHIVEQIKKNEEERSLQAEHREQEKEQMLAYLDRLQ--EEDLQDLERRHQEKLKMQAEI-KRINDENQR 295
Cdd:TIGR02168  739 EAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEelEAQIEQLKEELKALREALDELrAELTLLNEE 818

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408  296 QKAEMLAQERLADQMVMeftKKKMAREAEYEAEQEKIRREK-EKEIARLRALQEKAQDYQAEQDALRAKRNQEVADREWR 374
Cdd:TIGR02168  819 AANLRERLESLERRIAA---TERRLEDLEEQIEELSEDIESlAAEIEELEELIEELESELEALLNERASLEEALALLRSE 895

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408  375 RKEKENAQKKIETEEKLRKSRLEQVAFKEHTLAVQVQRDRDEFERILRAQREQIEREKQEQEKKAKGCLQHANELRRQVR 454
Cdd:TIGR02168  896 LEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLK 975


                   ....*
gi 1907070408  455 ENQQK 459
Cdd:TIGR02168  976 RLENK 980
MARTX_Nterm NF012221
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...
 144-359 1.27e-03

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.


Pssm-ID: 467957 [Multi-domain]  Cd Length: 1848  Bit Score: 41.74  E-value: 1.27e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408  144 AQNLLQ-----RADKLRMEQEE------------ELKDMSKIILNAKCHAIRDAQILEKQQIQKELDEEERRLDHMMEID 206
Cdd:NF012221  1557 AQNALAdkeraEADRQRLEQEKqqqlaaisgsqsQLESTDQNALETNGQAQRDAILEESRAVTKELTTLAQGLDALDSQA 1636

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408  207 rreslqrqedreRKRREERVRGKRHIVEQIKKNEEERSLQAEHREQEKeqmLAYLDRLQEEDLQDLER--RHQEKLKMQA 284
Cdd:NF012221  1637 ------------TYAGESGDQWRNPFAGGLLDRVQEQLDDAKKISGKQ---LADAKQRHVDNQQKVKDavAKSEAGVAQG 1701

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1907070408  285 EIKRINDENQRQKAEMLAQERLADQMVMEFTKKKMAREAEYEAEQEKIRREKEKEIARLRALQEKAQDYQAEQDA 359
Cdd:NF012221  1702 EQNQANAEQDIDDAKADAEKRKDDALAKQNEAQQAESDANAAANDAQSRGEQDASAAENKANQAQADAKGAKQDE 1776
MARTX_Nterm NF012221
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...
 231-413 1.31e-03

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.


Pssm-ID: 467957 [Multi-domain]  Cd Length: 1848  Bit Score: 41.74  E-value: 1.31e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408  231 HIVEQIKKNE-EERSLQAEHR--------EQEKEQMLAYLDRLQEE----DLQDLERRHQ-EKLKMQAEIKRINDE---- 292
Cdd:NF012221  1546 AVSKHAKQDDaAQNALADKERaeadrqrlEQEKQQQLAAISGSQSQlestDQNALETNGQaQRDAILEESRAVTKElttl 1625

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408  293 --------NQRQKAEMLAQ---ERLAD------QMVMEFTKKKMAREAE-----YEAEQEKIRREKEKEIARLRALQEKA 350
Cdd:NF012221  1626 aqgldaldSQATYAGESGDqwrNPFAGglldrvQEQLDDAKKISGKQLAdakqrHVDNQQKVKDAVAKSEAGVAQGEQNQ 1705

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1907070408  351 QDYQAEQDALRAKRNQEVADREWRRKEKENAQKKIETEEKLRKSRLEQVAFKEHTLAVQVQRD 413
Cdd:NF012221  1706 ANAEQDIDDAKADAEKRKDDALAKQNEAQQAESDANAAANDAQSRGEQDASAAENKANQAQAD 1768
 
Name Accession Description Interval E-value
TPH pfam13868
Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of ...
 155-495 9.31e-66

Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of eukaryotic proteins. Trichoplein or mitostatin, was first defined as a meiosis-specific nuclear structural protein. It has since been linked with mitochondrial movement. It is associated with the mitochondrial outer membrane, and over-expression leads to reduction in mitochondrial motility whereas lack of it enhances mitochondrial movement. The activity appears to be mediated through binding the mitochondria to the actin intermediate filaments (IFs). The family is in the trichohyalin-plectin-homology domain.


Pssm-ID: 464007 [Multi-domain]  Cd Length: 341  Bit Score: 216.32  E-value: 9.31e-66
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408 155 RMEQEEELKDMSKIILNAKCHAIRDAQILEKQQIQKELDEEERRLDHMMEIDRRESLQRQEDRERKRREERVRGKRHIVE 234
Cdd:pfam13868   1 LRENSDELRELNSKLLAAKCNKERDAQIAEKKRIKAEEKEEERRLDEMMEEERERALEEEEEKEEERKEERKRYRQELEE 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408 235 QIKKNEEERSLQAEHREQEKEQMLAYLDRLQEEDLQDLERRHQEKLKMQAEIKRINDENQRQKAEMLAQERLADQMVMEF 314
Cdd:pfam13868  81 QIEEREQKRQEEYEEKLQEREQMDEIVERIQEEDQAEAEEKLEKQRQLREEIDEFNEEQAEWKELEKEEEREEDERILEY 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408 315 TKKKMAREAEYEAEQEKIRREKEKEIARLRALQEKAQDYQAEQDALRAKRNQEVADREWRRKEKENAQKKIETEEKLRKS 394
Cdd:pfam13868 161 LKEKAEREEEREAEREEIEEEKEREIARLRAQQEKAQDEKAERDELRAKLYQEEQERKERQKEREEAEKKARQRQELQQA 240

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408 395 RLEQVAFKEHTLAVQVQRDRDEFERILRAQREQIEREKQEQEKKAKGCLQHANELRRQVRENQQKHVQNRLATFEEGRRL 474
Cdd:pfam13868 241 REEQIELKERRLAEEAEREEEEFERMLRKQAEDEEIEQEEAEKRRMKRLEHRRELEKQIEEREEQRAAEREEELEEGERL 320

                         330       340
                  ....*....|....*....|.
gi 1907070408 475 KEEAEKRRERIEDIKKQKLEE 495
Cdd:pfam13868 321 REEEAERRERIEEERQKKLKE 341
PTZ00121 PTZ00121
MAEBL; Provisional
 81-522 4.21e-10

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 62.85  E-value: 4.21e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408   81 ERIKWASQVLTKEELNAREQALKKEKEGILEAVTIRKKIMKQKEMTWNNNKKLSDLEEVARERAQNLLQRADKLRMEQEE 160
Cdd:PTZ00121  1275 EEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEA 1354

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408  161 ELKDMSKIILNAKCHAIRDAQILEKQQIQKELDEEERRLDHMMEIDRRESLQRQEDRERKRREERVRGKRHIVEQIKKNE 240
Cdd:PTZ00121  1355 AADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKAD 1434

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408  241 EERSLQAEHREQEKEQMLAYLDRLQEEDLQDLE-RRHQEKLKMQAEIKRINDENQRQKAEMLAQERLADQMVMEFTKKKM 319
Cdd:PTZ00121  1435 EAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEeAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADE 1514

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408  320 AREAEYEAEQEKIRREKEKEIARLRALQEKAQDYQAEQDALRAKRNQEVADREWRRKEKENAQKKIETEEKLRKSRLEQV 399
Cdd:PTZ00121  1515 AKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARI 1594

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408  400 AFKEHTLAVQVQRDRDEFERILRAQREQIEREKQEQEKKAKGCLQH--------ANELRRQVRENQQKHVQNRLATFEEG 471
Cdd:PTZ00121  1595 EEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKkeaeekkkAEELKKAEEENKIKAAEEAKKAEEDK 1674

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1907070408  472 RR---LKEEAEKRRERIEDIKKQKLEELRATGLPEKYCIEVERKANILPATSVN 522
Cdd:PTZ00121  1675 KKaeeAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEEN 1728
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 241-495 7.53e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 58.41  E-value: 7.53e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408 241 EERSLQAEHREQEKEQMLAYLDRLQEEDLQDLERRHQEKLKMQAEIKRINDENQRQKAEMLAQERLADQMVMEFTKKKMA 320
Cdd:COG1196   235 RELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRREL 314

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408 321 REAEYEAEQE--KIRREKEKEIARLRALQEKAQDYQAEQDALRAKRNQEVADREWRRKEKENAQKKIETEEKLRKSRLEQ 398
Cdd:COG1196   315 EERLEELEEElaELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRA 394

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408 399 VAFKEHTLAVQVQRDRDEFERILRAQREQIEREKQEQEKKAKgcLQHANELRRQVRENQQKHVQNRLATFEEGRRLKEEA 478
Cdd:COG1196   395 AAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEE--EEEEEEALEEAAEEEAELEEEEEALLELLAELLEEA 472

                         250
                  ....*....|....*..
gi 1907070408 479 EKRRERIEDIKKQKLEE 495
Cdd:COG1196   473 ALLEAALAELLEELAEA 489
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 178-488 8.71e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 58.41  E-value: 8.71e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408 178 RDAQILEKQQIQKELDEEERRLDHMMEIDRRESLQRQEDRERKRREERVRGKRHIVEQIKKNEEERSLQaeHREQEKEQM 257
Cdd:COG1196   237 LEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIA--RLEERRREL 314

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408 258 LAYLDRLQEEDLQDLERRHQEKLKMQAEIKRINDENQRQKAEMLAQERLAdqmvmeftkkkmAREAEYEAEQEKIRREKE 337
Cdd:COG1196   315 EERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAE------------EALLEAEAELAEAEEELE 382

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408 338 KEIARLRALQEKAQDYQAEQDALRAKRNQEVADREWRRKEKENAQKKIETEEKLRKSRLEQVAFKEHTLAVQVQRDRDEF 417
Cdd:COG1196   383 ELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALL 462

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1907070408 418 ERILRAQREQIEREKQEQEKKAKgclqhanELRRQVRENQQKHVQNRLATFEEGRRLKEEAEKRRERIEDI 488
Cdd:COG1196   463 ELLAELLEEAALLEAALAELLEE-------LAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAV 526
PTZ00121 PTZ00121
MAEBL; Provisional
 81-497 1.49e-08

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 57.84  E-value: 1.49e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408   81 ERIKWASQVLTKEELNAREQALKKEKEGILEAVTIRKKIMKQKemtwnnnkKLSDLEEVARE--RAQNLLQRADKLRMEQ 158
Cdd:PTZ00121  1402 EDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAK--------KADEAKKKAEEakKAEEAKKKAEEAKKAD 1473

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408  159 E-----EELKDMSKIILNAKcHAIRDAQILEKQQIQKELDEEERRLDHMMEIDRRESLQRQEDRERKRREERVRGKRHI- 232
Cdd:PTZ00121  1474 EakkkaEEAKKADEAKKKAE-EAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELk 1552

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408  233 -VEQIKKNEEERSLQAEHREQEKEQMLA----YLDRLQEEDLQDLERRHQEKLKMQAEIKRiNDENQRQKAEMLAQERLA 307
Cdd:PTZ00121  1553 kAEELKKAEEKKKAEEAKKAEEDKNMALrkaeEAKKAEEARIEEVMKLYEEEKKMKAEEAK-KAEEAKIKAEELKKAEEE 1631

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408  308 DQMVMEFTKKkmarEAEYEAEQEKIRREKEKEIARLRALQEKAQDYQAEQDALRAKRNQEVADREWRRKEKENAQKKiet 387
Cdd:PTZ00121  1632 KKKVEQLKKK----EAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKA--- 1704

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408  388 eEKLRKSRLEQVAFKEhtlavqvQRDRDEFERILRAqrEQIEREKQEQEKKAKGCLQHANELRRQVRENQQKHVQNRLAT 467
Cdd:PTZ00121  1705 -EELKKKEAEEKKKAE-------ELKKAEEENKIKA--EEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIR 1774

                          410       420       430
                   ....*....|....*....|....*....|
gi 1907070408  468 FEEGRRLKEEAEKRRERIEDIKKQKLEELR 497
Cdd:PTZ00121  1775 KEKEAVIEEELDEEDEKRRMEVDKKIKDIF 1804
PTZ00121 PTZ00121
MAEBL; Provisional
 66-497 2.06e-08

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 57.46  E-value: 2.06e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408   66 EDPSGESLIISPEEFERIKWASQVLTKEELNAREQALKKEKEGILEAVTIRKKIMKQKEMTWNNNKKLSDLEEVARERaq 145
Cdd:PTZ00121  1313 EAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEK-- 1390

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408  146 nllQRADKLRMEQEEELKDMSKiiLNAKCHAIRDAQILEKQQIQKELDEEERRLDHMMEIDRRESLQRQEDRERKRREER 225
Cdd:PTZ00121  1391 ---KKADEAKKKAEEDKKKADE--LKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKK 1465

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408  226 VRGKRHIVEQIKKNEEERSL-QAEHREQEKEQMLAYLDRLQEEDLQDLERRHQEKLKMQAEIKRINDENQRQKAEMLAQE 304
Cdd:PTZ00121  1466 AEEAKKADEAKKKAEEAKKAdEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEK 1545

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408  305 RLADqmvmEFTKKKMAREAEYEAEQEKIRREKEKEIARLRALQEKAQDYQAEQDALRAKRNQEVADREWRRKEKENAQKK 384
Cdd:PTZ00121  1546 KKAD----ELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIK 1621

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408  385 IET-----EEKLRKSRLEQVAFKEHTLAVQVQRDRDE--FERILRAQREQIEREKQEQEKKAKGCLQHANELRRQVRENQ 457
Cdd:PTZ00121  1622 AEElkkaeEEKKKVEQLKKKEAEEKKKAEELKKAEEEnkIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEA 1701

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|...
gi 1907070408  458 QKHVQNRLATFEEGRR---LKEEAEKRRERIEDIKKQKLEELR 497
Cdd:PTZ00121  1702 KKAEELKKKEAEEKKKaeeLKKAEEENKIKAEEAKKEAEEDKK 1744
PTZ00121 PTZ00121
MAEBL; Provisional
 81-515 2.76e-08

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 57.07  E-value: 2.76e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408   81 ERIKWASQVLTKEELNAREQALKKEKEGilEAVTIRKKIMKQKEMTWNNNKKLSDLEEVARERAQNLLQRADKLRMEQEE 160
Cdd:PTZ00121  1339 EEAKKAAEAAKAEAEAAADEAEAAEEKA--EAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAA 1416

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408  161 ELKDMSkiiLNAKCHAIRDAQILEKQQIQKELDEE------ERRLDHMMEIDRRESLQRQEDRERKRREERVRGKRHIVE 234
Cdd:PTZ00121  1417 KKKADE---AKKKAEEKKKADEAKKKAEEAKKADEakkkaeEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAE 1493

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408  235 QIKKNEEERSLQAEHREQEKEQMLAYLDRLQEEDLQDLERRHQEKLKMQAEIKRINDENQRQKAEMLAQERLADQMVMEF 314
Cdd:PTZ00121  1494 EAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAE 1573

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408  315 TKKKMA-REAEYEAEQEKIRREKEKEIARLRALQEKAQDYQAEQDALRA---KRNQEVADREWRRKEKENAQKK----IE 386
Cdd:PTZ00121  1574 EDKNMAlRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAeelKKAEEEKKKVEQLKKKEAEEKKkaeeLK 1653

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408  387 TEEKLRKSRLEQVAFKEHTLAVQVQRDRDEfERILRAQREQIEREKQEQEKKAKGCLQHANELRRQvrENQQKHVQNRLA 466
Cdd:PTZ00121  1654 KAEEENKIKAAEEAKKAEEDKKKAEEAKKA-EEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKA--EELKKAEEENKI 1730

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1907070408  467 TFEEGRRLKEEAEKRRE--RIEDIKKQKLEELRATGLPEKYCIEVERKANI 515
Cdd:PTZ00121  1731 KAEEAKKEAEEDKKKAEeaKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVI 1781
PTZ00121 PTZ00121
MAEBL; Provisional
 103-514 5.71e-08

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 55.92  E-value: 5.71e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408  103 KKEKEGILEAVTIRKKIMKQKEMTWNNNKKLSDLEEVARERAQNLLQRADKLRMEQEEELKDMSKIILNAKCHAIRDAQI 182
Cdd:PTZ00121  1083 AKEDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAEDAKRVEIARKAED 1162

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408  183 LEKQQIQKELDEEER--RLDHMMEIDRRESLQRQEDRERKRREERVRGKRHI-----------VEQIKKNEEERSLQAEH 249
Cdd:PTZ00121  1163 ARKAEEARKAEDAKKaeAARKAEEVRKAEELRKAEDARKAEAARKAEEERKAeearkaedakkAEAVKKAEEAKKDAEEA 1242

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408  250 REQEKEQMLAYLDRLQEEDLQDLERRHQ----EKLKMQAEIKRINDENQRQKAEMLAQERLADQMVMEFTKKKMAREAEY 325
Cdd:PTZ00121  1243 KKAEEERNNEEIRKFEEARMAHFARRQAaikaEEARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKK 1322

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408  326 EAEQEKIRRE---KEKEIARLRALQEKAQDYQAEQDALRAKRNQEVADREWRRKEKENAQKKIETEEKLRKSRLEQVAFK 402
Cdd:PTZ00121  1323 KAEEAKKKADaakKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEE 1402

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408  403 EHTLAVQVQRDRDEFERILRAQREQIEREKQEQEKKAKGCLQHANELRRQVREnqQKHVQNRLATFEEGRRLKEEAEKRR 482
Cdd:PTZ00121  1403 DKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEE--AKKAEEAKKKAEEAKKADEAKKKAE 1480

                          410       420       430
                   ....*....|....*....|....*....|...
gi 1907070408  483 E-RIEDIKKQKLEELRATGLPEKYCIEVERKAN 514
Cdd:PTZ00121  1481 EaKKADEAKKKAEEAKKKADEAKKAAEAKKKAD 1513
PTZ00121 PTZ00121
MAEBL; Provisional
 194-497 9.08e-08

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 55.15  E-value: 9.08e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408  194 EEERRLDHMMEIDRRESLQRQEDRERKRREERVRGKRHIVEQIKKNEEERSLQAEHREQEKEQMLAYLDRLQEEDLQDLE 273
Cdd:PTZ00121  1221 EDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEE 1300

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408  274 RRHQEKLKMQAEIKRINDENQRQKAEMLAQERLADQMVMEFTKKKMAREAEYEAEQEKIRREKEK-EIARLRALQEKAQD 352
Cdd:PTZ00121  1301 KKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKaEAAEKKKEEAKKKA 1380

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408  353 YQAEQDALRAKRNQEVADREWRRKEKENAQKKIETEEK----LRKSRLEQVAFKEHTLAVQVQRDRDEFERILRAQREQI 428
Cdd:PTZ00121  1381 DAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKkadeAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAE 1460

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1907070408  429 EREKQEQEKKAKGCLQHANELRRQVRENQQKHVQNRLATfEEGRRLKEEAEKRRERIEDIKKQKLEELR 497
Cdd:PTZ00121  1461 EAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKA-DEAKKAAEAKKKADEAKKAEEAKKADEAK 1528
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 82-374 3.66e-07

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 53.02  E-value: 3.66e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408  82 RIKWASQVLTKEELNAREQALKKEKEGILEAVTIRKKIMKQKEMTWNNNKKLSDLEEVARERAQNLLQRADKLRMEQEEE 161
Cdd:COG1196   238 EAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEER 317

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408 162 LKDMSKIILNAKCHAIRDAQILEKQQIQKELDEEERRLDHMMEIDRRESLQRQEDRERKRREERVRGKRHIVEQIKKNEE 241
Cdd:COG1196   318 LEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAE 397

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408 242 ERSLQAEHREQEKEQMLAyLDRLQEEDLQDLERRHQEKLKMQAEIKRINDENQRQKAEMLAQERLADQMVmeftkKKMAR 321
Cdd:COG1196   398 LAAQLEELEEAEEALLER-LERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLA-----ELLEE 471

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|...
gi 1907070408 322 EAEYEAEQEKIRREKEKEIARLRALQEKAQDYQAEQDALRAKRNQEVADREWR 374
Cdd:COG1196   472 AALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAG 524
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 234-497 6.08e-07

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 52.05  E-value: 6.08e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408 234 EQIKKNEEERSLQAEHREQEKEQMLAyldRLQEEDLQDLERRHQEKLKMQA--EIKRINDENQRQKAEMLAQERLAdqmv 311
Cdd:pfam17380 299 ERLRQEKEEKAREVERRRKLEEAEKA---RQAEMDRQAAIYAEQERMAMERerELERIRQEERKRELERIRQEEIA---- 371

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408 312 MEFTKKKmareaeyeaEQEKIRREKEKEIARLRALQEKAQDYQAEQDALRAKRNQEVADREWRRKEKENA-QKKIETEEK 390
Cdd:pfam17380 372 MEISRMR---------ELERLQMERQQKNERVRQELEAARKVKILEEERQRKIQQQKVEMEQIRAEQEEArQREVRRLEE 442

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408 391 LRKSRLEQVAFKEHTLAVQVQRDR--DEFERILRAQREQIEREKQEQEKKAKGCLQHANELRRQV---RENQQKHVQNRL 465
Cdd:pfam17380 443 ERAREMERVRLEEQERQQQVERLRqqEEERKRKKLELEKEKRDRKRAEEQRRKILEKELEERKQAmieEERKRKLLEKEM 522

                         250       260       270
                  ....*....|....*....|....*....|....*..
gi 1907070408 466 -----ATFEEGRRLKEEAEKRRERIEDIKKQKLEELR 497
Cdd:pfam17380 523 eerqkAIYEEERRREAEEERRKQQEMEERRRIQEQMR 559
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 78-431 7.88e-07

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 52.05  E-value: 7.88e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408  78 EEFERIKWASQVLTKEELnAREQALKKEKEgilEAVTIRKKIMKQKEMTWNNNKKLSDLEEVARERAQNLLQRADKLRME 157
Cdd:pfam17380 291 EKFEKMEQERLRQEKEEK-AREVERRRKLE---EAEKARQAEMDRQAAIYAEQERMAMERERELERIRQEERKRELERIR 366

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408 158 QEEELKDMSKIilnakchairdaqiLEKQQIQKELDEEERRLDHMMEIDRRESLQRQEDrerkrreervrgKRHIVEQIK 237
Cdd:pfam17380 367 QEEIAMEISRM--------------RELERLQMERQQKNERVRQELEAARKVKILEEER------------QRKIQQQKV 420

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408 238 KNEEERSLQAEHREQEkeqmlayLDRLQEEDLQDLERRHQEKLKMQAEIKRINDENQRQKAEMLAQERLADQMVMEFTKK 317
Cdd:pfam17380 421 EMEQIRAEQEEARQRE-------VRRLEEERAREMERVRLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEEQR 493

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408 318 KMAREAEYEAEQEKIRREKEKeiarlRALQEKAQDyqaeqdalraKRNQEVADREWRRKEKENAQKKIETEEKLRKSRLE 397
Cdd:pfam17380 494 RKILEKELEERKQAMIEEERK-----RKLLEKEME----------ERQKAIYEEERRREAEEERRKQQEMEERRRIQEQM 558

                         330       340       350
                  ....*....|....*....|....*....|....
gi 1907070408 398 QVAFKEHTLAVQVQRDRDEFERILRAQREQIERE 431
Cdd:pfam17380 559 RKATEERSRLEAMEREREMMRQIVESEKARAEYE 592
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 90-491 1.80e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 50.71  E-value: 1.80e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408  90 LTKEELNAREQALKKEKEGILEAVTIRKKIMKQKEMTWNNNKKLSDLEEVARERAQNLLQRADKLRMEQEEELKDMSKII 169
Cdd:COG1196   384 LAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLE 463

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408 170 LNAKCHAIRDAQILEKQQIQKELDEEERRLDHMMEIDRRESLQRQEDRERKRREERVRGKRHIVEQIKKNEEERSLQAEH 249
Cdd:COG1196   464 LLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAA 543

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408 250 REQEkeqmLAYLDRLQEEDLQDLERRHQEKLKMQAEIKRINDENQRQKAEMLAQERLADQMVMEFtkkkmAREAEYEAEQ 329
Cdd:COG1196   544 LAAA----LQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLV-----ASDLREADAR 614

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408 330 EKIRREKEKEIARLRALQEKAQDYQAEQDALRAKRNQEVADREWRRKEKENAQKKIETEEKLRKSRLEQVAFKEHTLAVQ 409
Cdd:COG1196   615 YYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELE 694

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408 410 VQRDRDEFERILRAQREQIEREKQEQEKKAKGcLQHANELRRQVRENQQKHVQNRLATFEEGRRLKEEAEKRRERIEDIK 489
Cdd:COG1196   695 LEEALLAEEEEERELAEAEEERLEEELEEEAL-EEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLE 773


                  ..
gi 1907070408 490 KQ 491
Cdd:COG1196   774 RE 775
PTZ00121 PTZ00121
MAEBL; Provisional
 81-497 2.89e-06

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 50.52  E-value: 2.89e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408   81 ERIKWASQVLTKEELNAREQALKKEKEGILEAVTIRKKIMKQKEMTWNNNKKLSDLEEVARE--RAQNLLQRADKLRMEQ 158
Cdd:PTZ00121  1125 EDARKAEEARKAEDARKAEEARKAEDAKRVEIARKAEDARKAEEARKAEDAKKAEAARKAEEvrKAEELRKAEDARKAEA 1204

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408  159 EEELKDMSKIILNAKCHAIRDAQILEKQQIQKELDEEERRLDHMMEIDR-RESLQRQEDRERKRREERVRGKRHIVEQIK 237
Cdd:PTZ00121  1205 ARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEiRKFEEARMAHFARRQAAIKAEEARKADELK 1284

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408  238 KNEEERSLQAEHREQEKEQMLAYLDRLQEEDLQDLERRHQEKLKMQAEIKRINDENQRQKAEMLAQERLADQMVMEFTKK 317
Cdd:PTZ00121  1285 KAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEE 1364

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408  318 KmAREAEYEAEQEKIR----REKEKEIARLRALQEKAQDYQAEQDALRAKRNQEVADREWRRK--EKENAQKKIETEEKL 391
Cdd:PTZ00121  1365 K-AEAAEKKKEEAKKKadaaKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKaeEKKKADEAKKKAEEA 1443

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408  392 RKSRLEQVAFKEHTLAVQVQRDRDEFERILRAQREQIEREKQEQ-EKKAKGCLQHANELRRQVRENQQKHVQNRLATFEE 470
Cdd:PTZ00121  1444 KKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEaKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKK 1523

                          410       420
                   ....*....|....*....|....*....
gi 1907070408  471 GRRLK--EEAEKRRERIEDIKKQKLEELR 497
Cdd:PTZ00121  1524 ADEAKkaEEAKKADEAKKAEEKKKADELK 1552
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 251-498 1.07e-05

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 48.39  E-value: 1.07e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408 251 EQEKEQMLAYLDRLqeEDLQDLERRHQEKLKMQAEIKRINDENQRQKAEMLAQERLAdqmvmeftkkkmaREAEYEAEQE 330
Cdd:COG1196   178 ERKLEATEENLERL--EDILGELERQLEPLERQAEKAERYRELKEELKELEAELLLL-------------KLRELEAELE 242

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408 331 KIRREKEKEIARLRALQEKAQDYQAEQDALRAKRNQEVADREWRRKEKENAQKKIETEEKLRKSRLEQVAfkehtlavQV 410
Cdd:COG1196   243 ELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRR--------EL 314

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408 411 QRDRDEFERILRAQREQIEREKQE------QEKKAKGCLQHANELRRQVRENQQKHVQNRLATFEEGRRLKEEAEKRRER 484
Cdd:COG1196   315 EERLEELEEELAELEEELEELEEEleeleeELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRA 394

                         250
                  ....*....|....
gi 1907070408 485 IEDIKKQKLEELRA 498
Cdd:COG1196   395 AAELAAQLEELEEA 408
PTZ00121 PTZ00121
MAEBL; Provisional
 81-490 1.33e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 48.21  E-value: 1.33e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408   81 ERIKWASQVLTKEELNAREQALKKEKEGILEAVTIRKKIMKQKEMTWNNNKKLSDLEEVARERAQNLLQRADKLRMEQEE 160
Cdd:PTZ00121  1513 DEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEA 1592

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408  161 ELKDMSKIILNAKCHAIRDAQILEKQQIQKE---LDEEERRLDHMMEIDRRESLQRqedrerkrreervrgkrhiVEQIK 237
Cdd:PTZ00121  1593 RIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEelkKAEEEKKKVEQLKKKEAEEKKK-------------------AEELK 1653

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408  238 KNEEERSLQAEH--REQEKEQMLAYLDRLQEEDlqdlERRHQEKLKMQAEIKRINDENQRQKAEmlaQERLADQMvmeft 315
Cdd:PTZ00121  1654 KAEEENKIKAAEeaKKAEEDKKKAEEAKKAEED----EKKAAEALKKEAEEAKKAEELKKKEAE---EKKKAEEL----- 1721

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408  316 kKKMAREAEYEAEQEKIRREKEKEIArlralqEKAQDYQAEQDALRAKRNQEVADREWRRKEKENA-QKKIETEEKLRKS 394
Cdd:PTZ00121  1722 -KKAEEENKIKAEEAKKEAEEDKKKA------EEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAViEEELDEEDEKRRM 1794

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408  395 RLEQVAFKEHTLAVQVQRDRDEFERILRAQREQIEREKQEQEKKAKGCLQHANELRRQV--RENQQKHVQNRLATFEEGR 472
Cdd:PTZ00121  1795 EVDKKIKDIFDNFANIIEGGKEGNLVINDSKEMEDSAIKEVADSKNMQLEEADAFEKHKfnKNNENGEDGNKEADFNKEK 1874

                          410
                   ....*....|....*...
gi 1907070408  473 RLKEEAEKRRERIEDIKK 490
Cdd:PTZ00121  1875 DLKEDDEEEIEEADEIEK 1892
Caldesmon pfam02029
Caldesmon;
135-482 1.63e-05

Caldesmon;


Pssm-ID: 460421 [Multi-domain]  Cd Length: 495  Bit Score: 47.55  E-value: 1.63e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408 135 DLEEVARERAQNllQRADKLRMEQEEELKDMSKIILNAKCHAIRDAQILEKQQIQKELDEEERRLDHM--MEIDRRESLQ 212
Cdd:pfam02029   3 DEEEAARERRRR--AREERRRQKEEEEPSGQVTESVEPNEHNSYEEDSELKPSGQGGLDEEEAFLDRTakREERRQKRLQ 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408 213 RQEDRERKRREERVRGKRHIVEQIKKNEEERSLQAEHREQEKEQmlayLDRLQEEDLQDLERRHQEKLKMQAEIKRINDE 292
Cdd:pfam02029  81 EALERQKEFDPTIADEKESVAERKENNEEEENSSWEKEEKRDSR----LGRYKEEETEIREKEYQENKWSTEVRQAEEEG 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408 293 NQRQKAEMLAQERLADQMVMEFTKKKMAREAEYEAEQEKIRREKEKEIArlralQEKAQDYQAEQDALRAKRNQEVADRE 372
Cdd:pfam02029 157 EEEEDKSEEAEEVPTENFAKEEVKDEKIKKEKKVKYESKVFLDQKRGHP-----EVKSQNGEEEVTKLKVTTKRRQGGLS 231

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408 373 WRRKEKENAQKKIETEEKLRKSRLEQVAfkehtlavqvqRDRDEFERILRAQRE-QIEREKQEQEKKAKGCLQHANELRR 451
Cdd:pfam02029 232 QSQEREEEAEVFLEAEQKLEELRRRRQE-----------KESEEFEKLRQKQQEaELELEELKKKREERRKLLEEEEQRR 300

                         330       340       350
                  ....*....|....*....|....*....|.
gi 1907070408 452 QVRENQQKhvqnrLATFEEGRRLKEEAEKRR 482
Cdd:pfam02029 301 KQEEAERK-----LREEEEKRRMKEEIERRR 326
YqiK COG2268
Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain [Function unknown];
317-441 6.56e-05

Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain [Function unknown];


Pssm-ID: 441869 [Multi-domain]  Cd Length: 439  Bit Score: 45.25  E-value: 6.56e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408 317 KKMAREAEYEAEQEKIRREKEKEIARLRALQEKAQDYQAEQDALRAKRNQEVADREWRRKEKENAQKKIETEEKLRKSRL 396
Cdd:COG2268   202 RIAEAEAERETEIAIAQANREAEEAELEQEREIETARIAEAEAELAKKKAEERREAETARAEAEAAYEIAEANAEREVQR 281

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*.
gi 1907070408 397 E-QVAFKEHTLAVQVQRDRDEFERILRAQREQIEREKQEQEKKAKG 441
Cdd:COG2268   282 QlEIAEREREIELQEKEAEREEAELEADVRKPAEAEKQAAEAEAEA 327
PTZ00266 PTZ00266
NIMA-related protein kinase; Provisional
 372-473 1.03e-04

NIMA-related protein kinase; Provisional


Pssm-ID: 173502 [Multi-domain]  Cd Length: 1021  Bit Score: 45.11  E-value: 1.03e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408  372 EWRRKEKENAQKKIETEEKLRKSRLEQVAfkehtlavQVQRDRDEFERILRAQREQIEREKQEQEKKAKGCLQHaNELRR 451
Cdd:PTZ00266   436 ERARIEKENAHRKALEMKILEKKRIERLE--------REERERLERERMERIERERLERERLERERLERDRLER-DRLDR 506

                           90       100
                   ....*....|....*....|..
gi 1907070408  452 QVRENQQKHVQNRLatfEEGRR 473
Cdd:PTZ00266   507 LERERVDRLERDRL---EKARR 525
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 140-459 1.15e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 45.05  E-value: 1.15e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408  140 ARERAQNLLQRADKLRmEQEEELKDMSkiilnAKCHAIRDAQI-LEKQQIQKELDEEERRLDHMMEIDRRESLQRQEDRE 218
Cdd:TIGR02168  665 SAKTNSSILERRREIE-ELEEKIEELE-----EKIAELEKALAeLRKELEELEEELEQLRKELEELSRQISALRKDLARL 738

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408  219 RKRREERVRGKRHIVEQIKKNEEERSLQAEHREQEKEQMLAYLDRLQ--EEDLQDLERRHQEKLKMQAEI-KRINDENQR 295
Cdd:TIGR02168  739 EAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEelEAQIEQLKEELKALREALDELrAELTLLNEE 818

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408  296 QKAEMLAQERLADQMVMeftKKKMAREAEYEAEQEKIRREK-EKEIARLRALQEKAQDYQAEQDALRAKRNQEVADREWR 374
Cdd:TIGR02168  819 AANLRERLESLERRIAA---TERRLEDLEEQIEELSEDIESlAAEIEELEELIEELESELEALLNERASLEEALALLRSE 895

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408  375 RKEKENAQKKIETEEKLRKSRLEQVAFKEHTLAVQVQRDRDEFERILRAQREQIEREKQEQEKKAKGCLQHANELRRQVR 454
Cdd:TIGR02168  896 LEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLK 975


                   ....*
gi 1907070408  455 ENQQK 459
Cdd:TIGR02168  976 RLENK 980
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
253-498 1.89e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 44.52  E-value: 1.89e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408  253 EKEQMLAYLDRLQEEdLQDLERRHQ------EKLKMQAEIKRINDENQRQKAEMLAQERLADQMVMEFTKKKMAreaEYE 326
Cdd:COG4913    219 EEPDTFEAADALVEH-FDDLERAHEaledarEQIELLEPIRELAERYAAARERLAELEYLRAALRLWFAQRRLE---LLE 294

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408  327 AEQEKIRREKEKEIARLRALQEKAQDYQAEQDALRAKRNQEVADRewrrkeKENAQKKIETEEKLRKsrleqvafkehtl 406
Cdd:COG4913    295 AELEELRAELARLEAELERLEARLDALREELDELEAQIRGNGGDR------LEQLEREIERLERELE------------- 355

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408  407 avQVQRDRDEFERILRAQREQIEREKQEqekkakgclqhANELRRQVRENQQKHVQNRLATFEEGRRLKEEAEKRRERIE 486
Cdd:COG4913    356 --ERERRRARLEALLAALGLPLPASAEE-----------FAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELR 422

                          250
                   ....*....|..
gi 1907070408  487 DIKKQkLEELRA 498
Cdd:COG4913    423 ELEAE-IASLER 433
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 178-499 2.22e-04

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 44.29  E-value: 2.22e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408  178 RDAQILEKQQIQKELDEEERRL-DHMMEIDRRESLQRQEDRERKRREERVRGKRHIVEQIKKNEEERSLQAEHREQEKEQ 256
Cdd:TIGR02169  690 LSSLQSELRRIENRLDELSQELsDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEE 769

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408  257 MLAYLDRLQEEdLQDLERR--HQEKLKMQAEIKRINDENQRQKAEMLAQER------LADQMVMEFTKKKMAREAEYEAE 328
Cdd:TIGR02169  770 LEEDLHKLEEA-LNDLEARlsHSRIPEIQAELSKLEEEVSRIEARLREIEQklnrltLEKEYLEKEIQELQEQRIDLKEQ 848

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408  329 QEKIRREKEKEIARLRALQEKAQDYQAEQDALRAKRNQEVADREWRRKEKENAQKKIETEE---KLRKSRLEQVAFKEHT 405
Cdd:TIGR02169  849 IKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEaqiEKKRKRLSELKAKLEA 928

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408  406 LAVQVQRDRDEFERILRAQREQIEREKQEQEKKAKGCLQHANELRRQVRENQQKHVQNRLATFEEGR-RLKEEAEKRRER 484
Cdd:TIGR02169  929 LEEELSEIEDPKGEDEEIPEEELSLEDVQAELQRVEEEIRALEPVNMLAIQEYEEVLKRLDELKEKRaKLEEERKAILER 1008

                          330
                   ....*....|....*
gi 1907070408  485 IEDIKKQKLEELRAT 499
Cdd:TIGR02169 1009 IEEYEKKKREVFMEA 1023
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
320-498 3.62e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 43.37  E-value: 3.62e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408  320 AREAEYEAEQEKIRREKEKEIARLRALQEKAQDYQAEQDALrakrnQEVADREWRRKEKENAQKKI-ETEEKLRKSRLEQ 398
Cdd:COG4913    610 AKLAALEAELAELEEELAEAEERLEALEAELDALQERREAL-----QRLAEYSWDEIDVASAEREIaELEAELERLDASS 684

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408  399 VAFKEhtLAVQVQRDRDEFERiLRAQREQIEREKQEQEKKAKGCLQHANELRRQVRENQQKHVQNRLATFEEgRRLKEEA 478
Cdd:COG4913    685 DDLAA--LEEQLEELEAELEE-LEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEE-RFAAALG 760

                          170       180
                   ....*....|....*....|
gi 1907070408  479 EKRRERIEDIKKQKLEELRA 498
Cdd:COG4913    761 DAVERELRENLEERIDALRA 780
tolA PRK09510
cell envelope integrity inner membrane protein TolA; Provisional
 243-390 6.54e-04

cell envelope integrity inner membrane protein TolA; Provisional


Pssm-ID: 236545 [Multi-domain]  Cd Length: 387  Bit Score: 42.10  E-value: 6.54e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408 243 RSLQAEHREQEKEQMLAYLDRLQEEDLQDLERRHQEKLKmQAEIKRINDENQRQKAEMLAQERLADQMVMEFTKKKMARE 322
Cdd:PRK09510   66 RQQQQQKSAKRAEEQRKKKEQQQAEELQQKQAAEQERLK-QLEKERLAAQEQKKQAEEAAKQAALKQKQAEEAAAKAAAA 144

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1907070408 323 AEYEAEQEkirrEKEKEIARLRALQEKAQDYQAEQDALRAKRNQEVADREWRRKEKENAQKKIETEEK 390
Cdd:PRK09510  145 AKAKAEAE----AKRAAAAAKKAAAEAKKKAEAEAAKKAAAEAKKKAEAEAAAKAAAEAKKKAEAEAK 208
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 239-498 1.03e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 41.97  E-value: 1.03e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408  239 NEEERSLQAEHREQEK-EQMLAYLDRLQEEDLQDLERRHQEKLKMQAEIKRINDENQRQKAEMLAQERLADQMVMEFTKK 317
Cdd:TIGR02168  196 NELERQLKSLERQAEKaERYKELKAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLE 275

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408  318 KMAREAEYEAEQEK---IRREKEKEIARLRALQEKAQDYQAEQDALRAKRNQEVADREWRRKEKENAQKKIETEEKLRKS 394
Cdd:TIGR02168  276 VSELEEEIEELQKElyaLANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELES 355

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408  395 RLEQVAFKEHTLAvqvqrdrdEFERILRAQREQIEREKQEQEKKAKGCLQHANELRRQVR--ENQQKHVQNRLATFEEGR 472
Cdd:TIGR02168  356 LEAELEELEAELE--------ELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEArlERLEDRRERLQQEIEELL 427

                          250       260
                   ....*....|....*....|....*..
gi 1907070408  473 RLKEEAEKRRERIE-DIKKQKLEELRA 498
Cdd:TIGR02168  428 KKLEEAELKELQAElEELEEELEELQE 454
PRK12704 PRK12704
phosphodiesterase; Provisional
 310-485 1.09e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 41.69  E-value: 1.09e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408 310 MVMEFTKKKMAREAEYEA----EQEKIRREKEKEIARLRAlQEKAQDYQAEQDALRAKRNQEVADREWRRKEKENA-QKK 384
Cdd:PRK12704   23 FVRKKIAEAKIKEAEEEAkrilEEAKKEAEAIKKEALLEA-KEEIHKLRNEFEKELRERRNELQKLEKRLLQKEENlDRK 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408 385 IETEEKlRKSRLEQVAFKEHTLAVQVQRDRDEFERILRAQREQIEREKQEQEKKAKgclqhaNELRRQVRENQQKHVQNR 464
Cdd:PRK12704  102 LELLEK-REEELEKKEKELEQKQQELEKKEEELEELIEEQLQELERISGLTAEEAK------EILLEKVEEEARHEAAVL 174

                         170       180
                  ....*....|....*....|.
gi 1907070408 465 LATFEEgrRLKEEAEKRRERI 485
Cdd:PRK12704  175 IKEIEE--EAKEEADKKAKEI 193
MARTX_Nterm NF012221
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...
 144-359 1.27e-03

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.


Pssm-ID: 467957 [Multi-domain]  Cd Length: 1848  Bit Score: 41.74  E-value: 1.27e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408  144 AQNLLQ-----RADKLRMEQEE------------ELKDMSKIILNAKCHAIRDAQILEKQQIQKELDEEERRLDHMMEID 206
Cdd:NF012221  1557 AQNALAdkeraEADRQRLEQEKqqqlaaisgsqsQLESTDQNALETNGQAQRDAILEESRAVTKELTTLAQGLDALDSQA 1636

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408  207 rreslqrqedreRKRREERVRGKRHIVEQIKKNEEERSLQAEHREQEKeqmLAYLDRLQEEDLQDLER--RHQEKLKMQA 284
Cdd:NF012221  1637 ------------TYAGESGDQWRNPFAGGLLDRVQEQLDDAKKISGKQ---LADAKQRHVDNQQKVKDavAKSEAGVAQG 1701

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1907070408  285 EIKRINDENQRQKAEMLAQERLADQMVMEFTKKKMAREAEYEAEQEKIRREKEKEIARLRALQEKAQDYQAEQDA 359
Cdd:NF012221  1702 EQNQANAEQDIDDAKADAEKRKDDALAKQNEAQQAESDANAAANDAQSRGEQDASAAENKANQAQADAKGAKQDE 1776
MARTX_Nterm NF012221
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...
 231-413 1.31e-03

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.


Pssm-ID: 467957 [Multi-domain]  Cd Length: 1848  Bit Score: 41.74  E-value: 1.31e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408  231 HIVEQIKKNE-EERSLQAEHR--------EQEKEQMLAYLDRLQEE----DLQDLERRHQ-EKLKMQAEIKRINDE---- 292
Cdd:NF012221  1546 AVSKHAKQDDaAQNALADKERaeadrqrlEQEKQQQLAAISGSQSQlestDQNALETNGQaQRDAILEESRAVTKElttl 1625

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408  293 --------NQRQKAEMLAQ---ERLAD------QMVMEFTKKKMAREAE-----YEAEQEKIRREKEKEIARLRALQEKA 350
Cdd:NF012221  1626 aqgldaldSQATYAGESGDqwrNPFAGglldrvQEQLDDAKKISGKQLAdakqrHVDNQQKVKDAVAKSEAGVAQGEQNQ 1705

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1907070408  351 QDYQAEQDALRAKRNQEVADREWRRKEKENAQKKIETEEKLRKSRLEQVAFKEHTLAVQVQRD 413
Cdd:NF012221  1706 ANAEQDIDDAKADAEKRKDDALAKQNEAQQAESDANAAANDAQSRGEQDASAAENKANQAQAD 1768
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
259-497 2.29e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 40.67  E-value: 2.29e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408  259 AYLDRLQEEdLQDLERRHQEKLKMQAEIKRINDENQRQKAemlAQERLADQmvmEFTKKKMAREAEYEAEQEKIRREKEK 338
Cdd:COG4913    610 AKLAALEAE-LAELEEELAEAEERLEALEAELDALQERRE---ALQRLAEY---SWDEIDVASAEREIAELEAELERLDA 682

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408  339 EIARLRALQEKAQDYQAEQDALRAKRNQEVADREWRRKEKENAQKKIEtEEKLRKSRLEQVAFKEHTLAVQVQRDRDEFE 418
Cdd:COG4913    683 SSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELD-ELQDRLEAAEDLARLELRALLEERFAAALGD 761

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408  419 RILRAQREQIEREKQEQEKKAKGCLQHANELRRQVRENQQKHVQNRLATFEEGrrlkEEAEKRRERIEDI----KKQKLE 494
Cdd:COG4913    762 AVERELRENLEERIDALRARLNRAEEELERAMRAFNREWPAETADLDADLESL----PEYLALLDRLEEDglpeYEERFK 837


                   ...
gi 1907070408  495 ELR 497
Cdd:COG4913    838 ELL 840
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
131-365 5.20e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 39.51  E-value: 5.20e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408  131 KKLSDLEEVARER---AQNLLQRADKLRmEQEEELKDMSKIILNAKCHAIRDAQILEKQQIQKELDEEERRLDHMMEIDR 207
Cdd:COG4913    204 KPIGDLDDFVREYmleEPDTFEAADALV-EHFDDLERAHEALEDAREQIELLEPIRELAERYAAARERLAELEYLRAALR 282

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408  208 RESLQRQEDRERKRREERVrgkrhivEQIKKNEEERSLQAEHREQEKEQMLAYLDRLQEEDLQDLERrhqeklkMQAEIK 287
Cdd:COG4913    283 LWFAQRRLELLEAELEELR-------AELARLEAELERLEARLDALREELDELEAQIRGNGGDRLEQ-------LEREIE 348

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408  288 RINDENQRQKAEMLAQERLADQMVM-------EFTKKK---MAREAEYEAEQEKIRREKEKEIARLRALQEKAQDYQAEQ 357
Cdd:COG4913    349 RLERELEERERRRARLEALLAALGLplpasaeEFAALRaeaAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEI 428


                   ....*...
gi 1907070408  358 DALRAKRN 365
Cdd:COG4913    429 ASLERRKS 436
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 329-498 5.99e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 38.98  E-value: 5.99e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408 329 QEKIRREKEKEIARLRALQEKAQDYQAEQDALRAKRNQEVADREWRRKEKENAQKKIETEEKLRKSRLEQVAFKEHTLAV 408
Cdd:COG4942    18 QADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRA 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408 409 QVQRDRDEFERILRAQREQIEREKQEQEKKAKGCLQHANELR--RQVRENQQKHVQNRLATFEEGRRLKEEAEKRRERIE 486
Cdd:COG4942    98 ELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQylKYLAPARREQAEELRADLAELAALRAELEAERAELE 177

                         170
                  ....*....|..
gi 1907070408 487 DIKKQKLEELRA 498
Cdd:COG4942   178 ALLAELEEERAA 189
PRK05035 PRK05035
electron transport complex protein RnfC; Provisional
 277-389 7.59e-03

electron transport complex protein RnfC; Provisional


Pssm-ID: 235334 [Multi-domain]  Cd Length: 695  Bit Score: 39.16  E-value: 7.59e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907070408 277 QEKlkmqAEIKRINDEnqRQKAEmLAQERL-ADQMVMEftKKKMAREAEYEAEQEKiRREKEKE-----IARLRALQEKA 350
Cdd:PRK05035  433 QAK----AEIRAIEQE--KKKAE-EAKARFeARQARLE--REKAAREARHKKAAEA-RAAKDKDavaaaLARVKAKKAAA 502

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 1907070408 351 QDYQAEQDALRAKRNQEVADREWRRKEKENAQKKIETEE 389
Cdd:PRK05035  503 TQPIVIKAGARPDNSAVIAAREARKAQARARQAEKQAAA 541
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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