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Conserved domains on  [gi|1907195297|ref|XP_036010545|]
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microtubule-associated protein 4 isoform X10 [Mus musculus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 891-920 5.86e-14

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


:

Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 66.28  E-value: 5.86e-14
                           10        20        30
                   ....*....|....*....|....*....|
gi 1907195297  891 VQIVSKKVSYSHIQSKCGSKDNIKHVPGGG 920
Cdd:pfam00418    1 VKIESKKLDFSKVQSKCGSKDNIKHKPGGG 30
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 922-951 9.46e-14

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


:

Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 65.90  E-value: 9.46e-14
                           10        20        30
                   ....*....|....*....|....*....|
gi 1907195297  922 VQIQNKKVDISKVSSKCGSKANIKHKPGGG 951
Cdd:pfam00418    1 VKIESKKLDFSKVQSKCGSKDNIKHKPGGG 30
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 953-983 2.10e-09

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


:

Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 53.57  E-value: 2.10e-09
                           10        20        30
                   ....*....|....*....|....*....|.
gi 1907195297  953 VKIESQKLNFKeKAQAKVGSLDNVGHLPAGG 983
Cdd:pfam00418    1 VKIESKKLDFS-KVQSKCGSKDNIKHKPGGG 30
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 830-851 8.90e-08

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


:

Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 48.95  E-value: 8.90e-08
                           10        20
                   ....*....|....*....|..
gi 1907195297  830 DLKSVRSKVGSTENIKHQPGGG 851
Cdd:pfam00418    9 DFSKVQSKCGSKDNIKHKPGGG 30
PHA03307 super family cl33723
transcriptional regulator ICP4; Provisional
 545-884 1.85e-05

transcriptional regulator ICP4; Provisional


The actual alignment was detected with superfamily member PHA03307:

Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 49.01  E-value: 1.85e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195297  545 APASDLALPLETKVATVPIKDKGTVQTEEKPREDSQLASMQHKGQSTVP-PCTASPEPVKAAEQMSTLPIDAPSPLENLE 623
Cdd:PHA03307    71 PPPGPGTEAPANESRSTPTWSLSTLAPASPAREGSPTPPGPSSPDPPPPtPPPASPPPSPAPDLSEMLRPVGSPGPPPAA 150

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195297  624 QKETPGSQPSEPCSGVSRQEEAKAAVGVTGNDITTPPNKEPPpspekkAKPITEAKVAEKRTS-PSKPSSAPALKPGPKt 702
Cdd:PHA03307   151 SPPAAGASPAAVASDAASSRQAALPLSSPEETARAPSSPPAE------PPPSTPPAAASPRPPrRSSPISASASSPAPA- 223

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195297  703 tPTVSKATSPSTLVSTGPSSRSPATTLPKRPTSIKTEGKPADVKRMTAKSASADLSRSKTTSASSvkrNTTPTGAAPPAG 782
Cdd:PHA03307   224 -PGRSAADDAGASSSDSSSSESSGCGWGPENECPLPRPAPITLPTRIWEASGWNGPSSRPGPASS---SSSPRERSPSPS 299

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195297  783 MTSTRVKPMSAPSRSSGALSVDKKPTSTKPSSSAPRVSRLATTVSAPDLKSVRSKVGSTENIKHQPGGGRAKVEKKTEAA 862
Cdd:PHA03307   300 PSSPGSGPAPSSPRASSSSSSSRESSSSSTSSSSESSRGAAVSPGPSPSRSPSPSRPPPPADPSSPRKRPRPSRAPSSPA 379

                          330       340
                   ....*....|....*....|..
gi 1907195297  863 TTAGKPEPNAVTKAAGSIASAQ 884
Cdd:PHA03307   380 ASAGRPTRRRARAAVAGRARRR 401
 
Name Accession Description Interval E-value
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 891-920 5.86e-14

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 66.28  E-value: 5.86e-14
                           10        20        30
                   ....*....|....*....|....*....|
gi 1907195297  891 VQIVSKKVSYSHIQSKCGSKDNIKHVPGGG 920
Cdd:pfam00418    1 VKIESKKLDFSKVQSKCGSKDNIKHKPGGG 30
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 922-951 9.46e-14

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 65.90  E-value: 9.46e-14
                           10        20        30
                   ....*....|....*....|....*....|
gi 1907195297  922 VQIQNKKVDISKVSSKCGSKANIKHKPGGG 951
Cdd:pfam00418    1 VKIESKKLDFSKVQSKCGSKDNIKHKPGGG 30
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 953-983 2.10e-09

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 53.57  E-value: 2.10e-09
                           10        20        30
                   ....*....|....*....|....*....|.
gi 1907195297  953 VKIESQKLNFKeKAQAKVGSLDNVGHLPAGG 983
Cdd:pfam00418    1 VKIESKKLDFS-KVQSKCGSKDNIKHKPGGG 30
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 830-851 8.90e-08

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 48.95  E-value: 8.90e-08
                           10        20
                   ....*....|....*....|..
gi 1907195297  830 DLKSVRSKVGSTENIKHQPGGG 851
Cdd:pfam00418    9 DFSKVQSKCGSKDNIKHKPGGG 30
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 545-884 1.85e-05

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 49.01  E-value: 1.85e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195297  545 APASDLALPLETKVATVPIKDKGTVQTEEKPREDSQLASMQHKGQSTVP-PCTASPEPVKAAEQMSTLPIDAPSPLENLE 623
Cdd:PHA03307    71 PPPGPGTEAPANESRSTPTWSLSTLAPASPAREGSPTPPGPSSPDPPPPtPPPASPPPSPAPDLSEMLRPVGSPGPPPAA 150

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195297  624 QKETPGSQPSEPCSGVSRQEEAKAAVGVTGNDITTPPNKEPPpspekkAKPITEAKVAEKRTS-PSKPSSAPALKPGPKt 702
Cdd:PHA03307   151 SPPAAGASPAAVASDAASSRQAALPLSSPEETARAPSSPPAE------PPPSTPPAAASPRPPrRSSPISASASSPAPA- 223

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195297  703 tPTVSKATSPSTLVSTGPSSRSPATTLPKRPTSIKTEGKPADVKRMTAKSASADLSRSKTTSASSvkrNTTPTGAAPPAG 782
Cdd:PHA03307   224 -PGRSAADDAGASSSDSSSSESSGCGWGPENECPLPRPAPITLPTRIWEASGWNGPSSRPGPASS---SSSPRERSPSPS 299

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195297  783 MTSTRVKPMSAPSRSSGALSVDKKPTSTKPSSSAPRVSRLATTVSAPDLKSVRSKVGSTENIKHQPGGGRAKVEKKTEAA 862
Cdd:PHA03307   300 PSSPGSGPAPSSPRASSSSSSSRESSSSSTSSSSESSRGAAVSPGPSPSRSPSPSRPPPPADPSSPRKRPRPSRAPSSPA 379

                          330       340
                   ....*....|....*....|..
gi 1907195297  863 TTAGKPEPNAVTKAAGSIASAQ 884
Cdd:PHA03307   380 ASAGRPTRRRARAAVAGRARRR 401
Herpes_BLLF1 pfam05109
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
 687-1041 1.24e-04

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 46.06  E-value: 1.24e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195297  687 PSKPSSAPALKPGPKTTPTVSKATSPSTLVSTGPSSRSPATTLPKrPTSIKTEGKPADvkrMTAKSASADLSRSKTTSAS 766
Cdd:pfam05109  449 PSSTHVPTNLTAPASTGPTVSTADVTSPTPAGTTSGASPVTPSPS-PRDNGTESKAPD---MTSPTSAVTTPTPNATSPT 524

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195297  767 SVKRNTTPTGAAPPAGMTStrvkPMSA-PSRSSGALSVDKKPTSTKPSSSAPRVSRLATT--VSAPDLKSVRSKVGSTE- 842
Cdd:pfam05109  525 PAVTTPTPNATSPTLGKTS----PTSAvTTPTPNATSPTPAVTTPTPNATIPTLGKTSPTsaVTTPTPNATSPTVGETSp 600

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195297  843 --NIKHQPGGGRAKvekkTEAATTAGKPEPNAVTKAAGSIASAQKPpagkvQIVSKKVSYSHIQSKCGSKDNIKHVP--- 917
Cdd:pfam05109  601 qaNTTNHTLGGTSS----TPVVTSPPKNATSAVTTGQHNITSSSTS-----SMSLRPSSISETLSPSTSDNSTSHMPllt 671

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195297  918 -----GGGNVQiqnkKVDISKVSSKCGSKANIKHKPGggdvkiesqklnfkEKAQAKvGSLDNVGHLPAGGAVKTEGGGS 992
Cdd:pfam05109  672 sahptGGENIT----QVTPASTSTHHVSTSSPAPRPG--------------TTSQAS-GPGNSSTSTKPGEVNVTKGTPP 732

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*....
gi 1907195297  993 EALPCPGPPAGEEPVIPEAAPDAGAPTSASGlSGHTTLSGGGDQREPQT 1041
Cdd:pfam05109  733 KNATSPQAPSGQKTAVPTVTSTGGKANSTTG-GKHTTGHGARTSTEPTT 780
 
Name Accession Description Interval E-value
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 891-920 5.86e-14

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 66.28  E-value: 5.86e-14
                           10        20        30
                   ....*....|....*....|....*....|
gi 1907195297  891 VQIVSKKVSYSHIQSKCGSKDNIKHVPGGG 920
Cdd:pfam00418    1 VKIESKKLDFSKVQSKCGSKDNIKHKPGGG 30
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 922-951 9.46e-14

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 65.90  E-value: 9.46e-14
                           10        20        30
                   ....*....|....*....|....*....|
gi 1907195297  922 VQIQNKKVDISKVSSKCGSKANIKHKPGGG 951
Cdd:pfam00418    1 VKIESKKLDFSKVQSKCGSKDNIKHKPGGG 30
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 953-983 2.10e-09

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 53.57  E-value: 2.10e-09
                           10        20        30
                   ....*....|....*....|....*....|.
gi 1907195297  953 VKIESQKLNFKeKAQAKVGSLDNVGHLPAGG 983
Cdd:pfam00418    1 VKIESKKLDFS-KVQSKCGSKDNIKHKPGGG 30
Tubulin-binding pfam00418
Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, ...
 830-851 8.90e-08

Tau and MAP protein, tubulin-binding repeat; This family includes the vertebrate proteins MAP2, MAP4 and Tau, as well as other animal homologs. MAP4 is present in many tissues but is usually absent from neurons; MAP2 and Tau are mainly neuronal. Members of this family have the ability to bind to and stabilize microtubules. As a result, they are involved in neuronal migration, supporting dendrite elongation, and regulating microtubules during mitotic metaphase. Note that Tau is involved in neurofibrillary tangle formation in Alzheimer's disease and some other dementias. This family features a C-terminal microtubule binding repeat that contains a conserved KXGS motif.


Pssm-ID: 459807 [Multi-domain]  Cd Length: 30  Bit Score: 48.95  E-value: 8.90e-08
                           10        20
                   ....*....|....*....|..
gi 1907195297  830 DLKSVRSKVGSTENIKHQPGGG 851
Cdd:pfam00418    9 DFSKVQSKCGSKDNIKHKPGGG 30
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 545-884 1.85e-05

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 49.01  E-value: 1.85e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195297  545 APASDLALPLETKVATVPIKDKGTVQTEEKPREDSQLASMQHKGQSTVP-PCTASPEPVKAAEQMSTLPIDAPSPLENLE 623
Cdd:PHA03307    71 PPPGPGTEAPANESRSTPTWSLSTLAPASPAREGSPTPPGPSSPDPPPPtPPPASPPPSPAPDLSEMLRPVGSPGPPPAA 150

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195297  624 QKETPGSQPSEPCSGVSRQEEAKAAVGVTGNDITTPPNKEPPpspekkAKPITEAKVAEKRTS-PSKPSSAPALKPGPKt 702
Cdd:PHA03307   151 SPPAAGASPAAVASDAASSRQAALPLSSPEETARAPSSPPAE------PPPSTPPAAASPRPPrRSSPISASASSPAPA- 223

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195297  703 tPTVSKATSPSTLVSTGPSSRSPATTLPKRPTSIKTEGKPADVKRMTAKSASADLSRSKTTSASSvkrNTTPTGAAPPAG 782
Cdd:PHA03307   224 -PGRSAADDAGASSSDSSSSESSGCGWGPENECPLPRPAPITLPTRIWEASGWNGPSSRPGPASS---SSSPRERSPSPS 299

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195297  783 MTSTRVKPMSAPSRSSGALSVDKKPTSTKPSSSAPRVSRLATTVSAPDLKSVRSKVGSTENIKHQPGGGRAKVEKKTEAA 862
Cdd:PHA03307   300 PSSPGSGPAPSSPRASSSSSSSRESSSSSTSSSSESSRGAAVSPGPSPSRSPSPSRPPPPADPSSPRKRPRPSRAPSSPA 379

                          330       340
                   ....*....|....*....|..
gi 1907195297  863 TTAGKPEPNAVTKAAGSIASAQ 884
Cdd:PHA03307   380 ASAGRPTRRRARAAVAGRARRR 401
Herpes_BLLF1 pfam05109
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
 687-1041 1.24e-04

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 46.06  E-value: 1.24e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195297  687 PSKPSSAPALKPGPKTTPTVSKATSPSTLVSTGPSSRSPATTLPKrPTSIKTEGKPADvkrMTAKSASADLSRSKTTSAS 766
Cdd:pfam05109  449 PSSTHVPTNLTAPASTGPTVSTADVTSPTPAGTTSGASPVTPSPS-PRDNGTESKAPD---MTSPTSAVTTPTPNATSPT 524

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195297  767 SVKRNTTPTGAAPPAGMTStrvkPMSA-PSRSSGALSVDKKPTSTKPSSSAPRVSRLATT--VSAPDLKSVRSKVGSTE- 842
Cdd:pfam05109  525 PAVTTPTPNATSPTLGKTS----PTSAvTTPTPNATSPTPAVTTPTPNATIPTLGKTSPTsaVTTPTPNATSPTVGETSp 600

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195297  843 --NIKHQPGGGRAKvekkTEAATTAGKPEPNAVTKAAGSIASAQKPpagkvQIVSKKVSYSHIQSKCGSKDNIKHVP--- 917
Cdd:pfam05109  601 qaNTTNHTLGGTSS----TPVVTSPPKNATSAVTTGQHNITSSSTS-----SMSLRPSSISETLSPSTSDNSTSHMPllt 671

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195297  918 -----GGGNVQiqnkKVDISKVSSKCGSKANIKHKPGggdvkiesqklnfkEKAQAKvGSLDNVGHLPAGGAVKTEGGGS 992
Cdd:pfam05109  672 sahptGGENIT----QVTPASTSTHHVSTSSPAPRPG--------------TTSQAS-GPGNSSTSTKPGEVNVTKGTPP 732

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*....
gi 1907195297  993 EALPCPGPPAGEEPVIPEAAPDAGAPTSASGlSGHTTLSGGGDQREPQT 1041
Cdd:pfam05109  733 KNATSPQAPSGQKTAVPTVTSTGGKANSTTG-GKHTTGHGARTSTEPTT 780
PHA03247 PHA03247
large tegument protein UL36; Provisional
 532-828 2.66e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 41.85  E-value: 2.66e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195297  532 LHSGTELIVDNSMAPAsdlalPLETKVATVPIKDKGTVQTEEKPREdSQLASMQHKGQSTVPPCTASPE-------PVKA 604
Cdd:PHA03247  2537 IRGLEELASDDAGDPP-----PPLPPAAPPAAPDRSVPPPRPAPRP-SEPAVTSRARRPDAPPQSARPRapvddrgDPRG 2610

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195297  605 AEQMSTLPIDAPSPlenleqkETPGSQPSEPCSGVSRQEEAKAAVGVTGNDITTPPNKEPPPSPEKKAKPiteakvaEKR 684
Cdd:PHA03247  2611 PAPPSPLPPDTHAP-------DPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRA-------AQA 2676

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195297  685 TSPSKPSSAPALKPGPKTTPTVSKATSPSTLVSTGPSSRSPATTLPKRPTSIKTEGKPADVKRMTAKSASADLSRSKTTS 764
Cdd:PHA03247  2677 SSPPQRPRRRAARPTVGSLTSLADPPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPAR 2756

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1907195297  765 ASSVKRNTTPTGAAPPAGMTSTRVKPMSAPSRSSGALSVDKKPTSTKPSSSAPRVSRLATTVSA 828
Cdd:PHA03247  2757 PARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPP 2820
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 575-891 5.06e-03

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 40.92  E-value: 5.06e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195297  575 PREDSQLASMqhkgqstVPPCTASPEPVKAAEQMSTLPIDAPSPlenlEQKETPGSQPSEPCSGVSRQEEAKAAVGVTGN 654
Cdd:PHA03307   169 SRQAALPLSS-------PEETARAPSSPPAEPPPSTPPAAASPR----PPRRSSPISASASSPAPAPGRSAADDAGASSS 237

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195297  655 DITTPPNKEPPPSPEKKakpiTEAKVAEKRTSPSKPSSAPALKPGPKTTPTVSKATSPSTLVSTGPSSRSPATTLPKRPT 734
Cdd:PHA03307   238 DSSSSESSGCGWGPENE----CPLPRPAPITLPTRIWEASGWNGPSSRPGPASSSSSPRERSPSPSPSSPGSGPAPSSPR 313

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195297  735 SIKTEGKPADVkrmtakSASADLSRSKTTSASSVkrnttPTGAAPPAGMTSTRVKPMSAPSRSSGALSVDKKPTSTKPSS 814
Cdd:PHA03307   314 ASSSSSSSRES------SSSSTSSSSESSRGAAV-----SPGPSPSRSPSPSRPPPPADPSSPRKRPRPSRAPSSPAASA 382

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1907195297  815 SAPRVSRLATTVSAPDLKSVRSKVgstenikhQPGGGRAKVEKKTEAATTAGKPEPNAVTKAAGSIASAQKPPAGKV 891
Cdd:PHA03307   383 GRPTRRRARAAVAGRARRRDATGR--------FPAGRPRPSPLDAGAASGAFYARYPLLTPSGEPWPGSPPPPPGRV 451
PHA03247 PHA03247
large tegument protein UL36; Provisional
 593-837 5.36e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 41.08  E-value: 5.36e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195297  593 PPCTASPEPVKAAEQMSTLPIDAPSP----LENLEQKETPGSQPSEPCSGvSRQEEAKAAVGvtgnditTPPNKEPPPSP 668
Cdd:PHA03247  2633 PAANEPDPHPPPTVPPPERPRDDPAPgrvsRPRRARRLGRAAQASSPPQR-PRRRAARPTVG-------SLTSLADPPPP 2704

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195297  669 EKKAKPITEAKVAEKRTSPSKPSSAPALKPGPKTTPTVSKATSPSTLVSTGPSSRSPATTLPKRPTSIKTEGKPADVKRM 748
Cdd:PHA03247  2705 PPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLT 2784

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907195297  749 TAKSASADLSRSKTTSASSVKRNTTPTGAAPPAGMTSTRVKPMSAPSRSSGALSVDKKPTSTKPS-----SSAP--RVSR 821
Cdd:PHA03247  2785 RPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSlplggSVAPggDVRR 2864

                          250
                   ....*....|....*.
gi 1907195297  822 LATTVSAPDLKSVRSK 837
Cdd:PHA03247  2865 RPPSRSPAAKPAAPAR 2880
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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