centrosomal protein CEP57L1 isoform X12 [Mus musculus]
Cep57_CLD and Cep57_MT_bd domain-containing protein( domain architecture ID 12163498)
Cep57_CLD and Cep57_MT_bd domain-containing protein
List of domain hits
Name | Accession | Description | Interval | E-value | ||||
Cep57_CLD | pfam14073 | Centrosome localization domain of Cep57; The CLD or centrosome localization domain of Cep57 is ... |
50-211 | 1.22e-54 | ||||
Centrosome localization domain of Cep57; The CLD or centrosome localization domain of Cep57 is found at the N-terminus, and lies approximately between residues 58 and 239. This region lies within the first alpha-helical coiled-coil segment of Cep57, and localizes to the centrosome internally to gamma-tubulin, suggesting that it is either on both centrioles or on a centromatrix component. This N-terminal region can also multimerize with the N-terminus of other Cep57 molecules. The C-terminal part, Family Cep57_MT_bd, pfam06657, is the microtubule-binding region of Cep57. : Pssm-ID: 464080 [Multi-domain] Cd Length: 178 Bit Score: 178.97 E-value: 1.22e-54
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Cep57_MT_bd | pfam06657 | Centrosome microtubule-binding domain of Cep57; This C-terminal region of Cep57 binds, ... |
267-340 | 6.62e-16 | ||||
Centrosome microtubule-binding domain of Cep57; This C-terminal region of Cep57 binds, nucleates and bundles microtubules. The N-terminal part, family Cep57_CLD, pfam14073, is the centrosome localization domain Cep57. : Pssm-ID: 461976 [Multi-domain] Cd Length: 77 Bit Score: 72.22 E-value: 6.62e-16
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Name | Accession | Description | Interval | E-value | ||||
Cep57_CLD | pfam14073 | Centrosome localization domain of Cep57; The CLD or centrosome localization domain of Cep57 is ... |
50-211 | 1.22e-54 | ||||
Centrosome localization domain of Cep57; The CLD or centrosome localization domain of Cep57 is found at the N-terminus, and lies approximately between residues 58 and 239. This region lies within the first alpha-helical coiled-coil segment of Cep57, and localizes to the centrosome internally to gamma-tubulin, suggesting that it is either on both centrioles or on a centromatrix component. This N-terminal region can also multimerize with the N-terminus of other Cep57 molecules. The C-terminal part, Family Cep57_MT_bd, pfam06657, is the microtubule-binding region of Cep57. Pssm-ID: 464080 [Multi-domain] Cd Length: 178 Bit Score: 178.97 E-value: 1.22e-54
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Cep57_MT_bd | pfam06657 | Centrosome microtubule-binding domain of Cep57; This C-terminal region of Cep57 binds, ... |
267-340 | 6.62e-16 | ||||
Centrosome microtubule-binding domain of Cep57; This C-terminal region of Cep57 binds, nucleates and bundles microtubules. The N-terminal part, family Cep57_CLD, pfam14073, is the centrosome localization domain Cep57. Pssm-ID: 461976 [Multi-domain] Cd Length: 77 Bit Score: 72.22 E-value: 6.62e-16
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Smc | COG1196 | Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
49-175 | 5.98e-06 | ||||
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 48.78 E-value: 5.98e-06
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GBP_C | cd16269 | Guanylate-binding protein, C-terminal domain; Guanylate-binding protein (GBP), C-terminal ... |
49-165 | 4.81e-03 | ||||
Guanylate-binding protein, C-terminal domain; Guanylate-binding protein (GBP), C-terminal domain. Guanylate-binding proteins (GBPs) are synthesized after activation of the cell by interferons. The biochemical properties of GBPs are clearly different from those of Ras-like and heterotrimeric GTP-binding proteins. They bind guanine nucleotides with low affinity (micromolar range), are stable in their absence, and have a high turnover GTPase. In addition to binding GDP/GTP, they have the unique ability to bind GMP with equal affinity and hydrolyze GTP not only to GDP, but also to GMP. This C-terminal domain has been shown to mediate inhibition of endothelial cell proliferation by inflammatory cytokines. Pssm-ID: 293879 [Multi-domain] Cd Length: 291 Bit Score: 38.71 E-value: 4.81e-03
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PRK00409 | PRK00409 | recombination and DNA strand exchange inhibitor protein; Reviewed |
56-154 | 9.74e-03 | ||||
recombination and DNA strand exchange inhibitor protein; Reviewed Pssm-ID: 234750 [Multi-domain] Cd Length: 782 Bit Score: 38.27 E-value: 9.74e-03
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Name | Accession | Description | Interval | E-value | ||||
Cep57_CLD | pfam14073 | Centrosome localization domain of Cep57; The CLD or centrosome localization domain of Cep57 is ... |
50-211 | 1.22e-54 | ||||
Centrosome localization domain of Cep57; The CLD or centrosome localization domain of Cep57 is found at the N-terminus, and lies approximately between residues 58 and 239. This region lies within the first alpha-helical coiled-coil segment of Cep57, and localizes to the centrosome internally to gamma-tubulin, suggesting that it is either on both centrioles or on a centromatrix component. This N-terminal region can also multimerize with the N-terminus of other Cep57 molecules. The C-terminal part, Family Cep57_MT_bd, pfam06657, is the microtubule-binding region of Cep57. Pssm-ID: 464080 [Multi-domain] Cd Length: 178 Bit Score: 178.97 E-value: 1.22e-54
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Cep57_MT_bd | pfam06657 | Centrosome microtubule-binding domain of Cep57; This C-terminal region of Cep57 binds, ... |
267-340 | 6.62e-16 | ||||
Centrosome microtubule-binding domain of Cep57; This C-terminal region of Cep57 binds, nucleates and bundles microtubules. The N-terminal part, family Cep57_CLD, pfam14073, is the centrosome localization domain Cep57. Pssm-ID: 461976 [Multi-domain] Cd Length: 77 Bit Score: 72.22 E-value: 6.62e-16
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Smc | COG1196 | Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
49-175 | 5.98e-06 | ||||
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 48.78 E-value: 5.98e-06
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Smc | COG1196 | Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
49-177 | 6.71e-05 | ||||
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 45.31 E-value: 6.71e-05
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Smc | COG1196 | Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
49-177 | 2.63e-04 | ||||
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 43.39 E-value: 2.63e-04
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Smc | COG1196 | Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
49-177 | 1.35e-03 | ||||
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 41.08 E-value: 1.35e-03
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ClpA | COG0542 | ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ... |
53-161 | 1.98e-03 | ||||
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones]; Pssm-ID: 440308 [Multi-domain] Cd Length: 836 Bit Score: 40.45 E-value: 1.98e-03
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Smc | COG1196 | Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
49-177 | 4.04e-03 | ||||
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 39.53 E-value: 4.04e-03
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GBP_C | cd16269 | Guanylate-binding protein, C-terminal domain; Guanylate-binding protein (GBP), C-terminal ... |
49-165 | 4.81e-03 | ||||
Guanylate-binding protein, C-terminal domain; Guanylate-binding protein (GBP), C-terminal domain. Guanylate-binding proteins (GBPs) are synthesized after activation of the cell by interferons. The biochemical properties of GBPs are clearly different from those of Ras-like and heterotrimeric GTP-binding proteins. They bind guanine nucleotides with low affinity (micromolar range), are stable in their absence, and have a high turnover GTPase. In addition to binding GDP/GTP, they have the unique ability to bind GMP with equal affinity and hydrolyze GTP not only to GDP, but also to GMP. This C-terminal domain has been shown to mediate inhibition of endothelial cell proliferation by inflammatory cytokines. Pssm-ID: 293879 [Multi-domain] Cd Length: 291 Bit Score: 38.71 E-value: 4.81e-03
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Smc | COG1196 | Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
55-177 | 9.48e-03 | ||||
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 38.38 E-value: 9.48e-03
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PRK00409 | PRK00409 | recombination and DNA strand exchange inhibitor protein; Reviewed |
56-154 | 9.74e-03 | ||||
recombination and DNA strand exchange inhibitor protein; Reviewed Pssm-ID: 234750 [Multi-domain] Cd Length: 782 Bit Score: 38.27 E-value: 9.74e-03
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Blast search parameters | ||||
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