integrin alpha-7 isoform X6 [Mus musculus]
Protein Classification
integrin alpha( domain architecture ID 12192630)
integrin alpha is a transmembrane receptor that facilitates cell-extracellular matrix (ECM) adhesion
List of domain hits
| Name | Accession | Description | Interval | E-value | ||||||||
| Integrin_alpha2 | pfam08441 | Integrin alpha; This domain is found in integrin alpha and integrin alpha precursors to the C ... |
304-793 | 1.21e-158 | ||||||||
Integrin alpha; This domain is found in integrin alpha and integrin alpha precursors to the C terminus of a number of pfam01839 repeats and to the N-terminus of the pfam00357 cytoplasmic region. This region is composed of three immunoglobulin-like domains. : Pssm-ID: 462478 [Multi-domain] Cd Length: 449 Bit Score: 474.12 E-value: 1.21e-158
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| Int_alpha | smart00191 | Integrin alpha (beta-propellor repeats); Integrins are cell adhesion molecules that mediate ... |
209-261 | 1.04e-15 | ||||||||
Integrin alpha (beta-propellor repeats); Integrins are cell adhesion molecules that mediate cell-extracellular matrix and cell-cell interactions. They contain both alpha and beta subunits. Alpha integrins are proposed to contain a domain containing a 7-fold repeat that adopts a beta-propellor fold. Some of these domains contain an inserted von Willebrand factor type-A domain. Some repeats contain putative calcium-binding sites. The 7-fold repeat domain is homologous to a similar domain in phosphatidylinositol-glycan-specific phospholipase D. : Pssm-ID: 214549 [Multi-domain] Cd Length: 57 Bit Score: 72.02 E-value: 1.04e-15
|
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| Int_alpha | smart00191 | Integrin alpha (beta-propellor repeats); Integrins are cell adhesion molecules that mediate ... |
150-203 | 3.55e-11 | ||||||||
Integrin alpha (beta-propellor repeats); Integrins are cell adhesion molecules that mediate cell-extracellular matrix and cell-cell interactions. They contain both alpha and beta subunits. Alpha integrins are proposed to contain a domain containing a 7-fold repeat that adopts a beta-propellor fold. Some of these domains contain an inserted von Willebrand factor type-A domain. Some repeats contain putative calcium-binding sites. The 7-fold repeat domain is homologous to a similar domain in phosphatidylinositol-glycan-specific phospholipase D. : Pssm-ID: 214549 [Multi-domain] Cd Length: 57 Bit Score: 59.31 E-value: 3.55e-11
|
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| Int_alpha | smart00191 | Integrin alpha (beta-propellor repeats); Integrins are cell adhesion molecules that mediate ... |
271-311 | 8.80e-06 | ||||||||
Integrin alpha (beta-propellor repeats); Integrins are cell adhesion molecules that mediate cell-extracellular matrix and cell-cell interactions. They contain both alpha and beta subunits. Alpha integrins are proposed to contain a domain containing a 7-fold repeat that adopts a beta-propellor fold. Some of these domains contain an inserted von Willebrand factor type-A domain. Some repeats contain putative calcium-binding sites. The 7-fold repeat domain is homologous to a similar domain in phosphatidylinositol-glycan-specific phospholipase D. : Pssm-ID: 214549 [Multi-domain] Cd Length: 57 Bit Score: 43.90 E-value: 8.80e-06
|
||||||||||||
| Int_alpha | smart00191 | Integrin alpha (beta-propellor repeats); Integrins are cell adhesion molecules that mediate ... |
92-143 | 1.04e-04 | ||||||||
Integrin alpha (beta-propellor repeats); Integrins are cell adhesion molecules that mediate cell-extracellular matrix and cell-cell interactions. They contain both alpha and beta subunits. Alpha integrins are proposed to contain a domain containing a 7-fold repeat that adopts a beta-propellor fold. Some of these domains contain an inserted von Willebrand factor type-A domain. Some repeats contain putative calcium-binding sites. The 7-fold repeat domain is homologous to a similar domain in phosphatidylinositol-glycan-specific phospholipase D. : Pssm-ID: 214549 [Multi-domain] Cd Length: 57 Bit Score: 40.82 E-value: 1.04e-04
|
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| Name | Accession | Description | Interval | E-value | ||||||||
| Integrin_alpha2 | pfam08441 | Integrin alpha; This domain is found in integrin alpha and integrin alpha precursors to the C ... |
304-793 | 1.21e-158 | ||||||||
Integrin alpha; This domain is found in integrin alpha and integrin alpha precursors to the C terminus of a number of pfam01839 repeats and to the N-terminus of the pfam00357 cytoplasmic region. This region is composed of three immunoglobulin-like domains. Pssm-ID: 462478 [Multi-domain] Cd Length: 449 Bit Score: 474.12 E-value: 1.21e-158
|
||||||||||||
| Int_alpha | smart00191 | Integrin alpha (beta-propellor repeats); Integrins are cell adhesion molecules that mediate ... |
209-261 | 1.04e-15 | ||||||||
Integrin alpha (beta-propellor repeats); Integrins are cell adhesion molecules that mediate cell-extracellular matrix and cell-cell interactions. They contain both alpha and beta subunits. Alpha integrins are proposed to contain a domain containing a 7-fold repeat that adopts a beta-propellor fold. Some of these domains contain an inserted von Willebrand factor type-A domain. Some repeats contain putative calcium-binding sites. The 7-fold repeat domain is homologous to a similar domain in phosphatidylinositol-glycan-specific phospholipase D. Pssm-ID: 214549 [Multi-domain] Cd Length: 57 Bit Score: 72.02 E-value: 1.04e-15
|
||||||||||||
| Int_alpha | smart00191 | Integrin alpha (beta-propellor repeats); Integrins are cell adhesion molecules that mediate ... |
150-203 | 3.55e-11 | ||||||||
Integrin alpha (beta-propellor repeats); Integrins are cell adhesion molecules that mediate cell-extracellular matrix and cell-cell interactions. They contain both alpha and beta subunits. Alpha integrins are proposed to contain a domain containing a 7-fold repeat that adopts a beta-propellor fold. Some of these domains contain an inserted von Willebrand factor type-A domain. Some repeats contain putative calcium-binding sites. The 7-fold repeat domain is homologous to a similar domain in phosphatidylinositol-glycan-specific phospholipase D. Pssm-ID: 214549 [Multi-domain] Cd Length: 57 Bit Score: 59.31 E-value: 3.55e-11
|
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| FG-GAP | pfam01839 | FG-GAP repeat; This family contains the extracellular repeat that is found in up to seven ... |
152-190 | 1.05e-10 | ||||||||
FG-GAP repeat; This family contains the extracellular repeat that is found in up to seven copies in alpha integrins. This repeat has been predicted to fold into a beta propeller structure. The repeat is called the FG-GAP repeat after two conserved motifs in the repeat. The FG-GAP repeats are found in the N terminus of integrin alpha chains, a region that has been shown to be important for ligand binding. A putative Ca2+ binding motif is found in some of the repeats. Pssm-ID: 460357 Cd Length: 36 Bit Score: 57.14 E-value: 1.05e-10
|
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| FG-GAP | pfam01839 | FG-GAP repeat; This family contains the extracellular repeat that is found in up to seven ... |
213-246 | 6.42e-08 | ||||||||
FG-GAP repeat; This family contains the extracellular repeat that is found in up to seven copies in alpha integrins. This repeat has been predicted to fold into a beta propeller structure. The repeat is called the FG-GAP repeat after two conserved motifs in the repeat. The FG-GAP repeats are found in the N terminus of integrin alpha chains, a region that has been shown to be important for ligand binding. A putative Ca2+ binding motif is found in some of the repeats. Pssm-ID: 460357 Cd Length: 36 Bit Score: 49.43 E-value: 6.42e-08
|
||||||||||||
| Int_alpha | smart00191 | Integrin alpha (beta-propellor repeats); Integrins are cell adhesion molecules that mediate ... |
271-311 | 8.80e-06 | ||||||||
Integrin alpha (beta-propellor repeats); Integrins are cell adhesion molecules that mediate cell-extracellular matrix and cell-cell interactions. They contain both alpha and beta subunits. Alpha integrins are proposed to contain a domain containing a 7-fold repeat that adopts a beta-propellor fold. Some of these domains contain an inserted von Willebrand factor type-A domain. Some repeats contain putative calcium-binding sites. The 7-fold repeat domain is homologous to a similar domain in phosphatidylinositol-glycan-specific phospholipase D. Pssm-ID: 214549 [Multi-domain] Cd Length: 57 Bit Score: 43.90 E-value: 8.80e-06
|
||||||||||||
| Int_alpha | smart00191 | Integrin alpha (beta-propellor repeats); Integrins are cell adhesion molecules that mediate ... |
92-143 | 1.04e-04 | ||||||||
Integrin alpha (beta-propellor repeats); Integrins are cell adhesion molecules that mediate cell-extracellular matrix and cell-cell interactions. They contain both alpha and beta subunits. Alpha integrins are proposed to contain a domain containing a 7-fold repeat that adopts a beta-propellor fold. Some of these domains contain an inserted von Willebrand factor type-A domain. Some repeats contain putative calcium-binding sites. The 7-fold repeat domain is homologous to a similar domain in phosphatidylinositol-glycan-specific phospholipase D. Pssm-ID: 214549 [Multi-domain] Cd Length: 57 Bit Score: 40.82 E-value: 1.04e-04
|
||||||||||||
| Name | Accession | Description | Interval | E-value | ||||||||
| Integrin_alpha2 | pfam08441 | Integrin alpha; This domain is found in integrin alpha and integrin alpha precursors to the C ... |
304-793 | 1.21e-158 | ||||||||
Integrin alpha; This domain is found in integrin alpha and integrin alpha precursors to the C terminus of a number of pfam01839 repeats and to the N-terminus of the pfam00357 cytoplasmic region. This region is composed of three immunoglobulin-like domains. Pssm-ID: 462478 [Multi-domain] Cd Length: 449 Bit Score: 474.12 E-value: 1.21e-158
|
||||||||||||
| Int_alpha | smart00191 | Integrin alpha (beta-propellor repeats); Integrins are cell adhesion molecules that mediate ... |
209-261 | 1.04e-15 | ||||||||
Integrin alpha (beta-propellor repeats); Integrins are cell adhesion molecules that mediate cell-extracellular matrix and cell-cell interactions. They contain both alpha and beta subunits. Alpha integrins are proposed to contain a domain containing a 7-fold repeat that adopts a beta-propellor fold. Some of these domains contain an inserted von Willebrand factor type-A domain. Some repeats contain putative calcium-binding sites. The 7-fold repeat domain is homologous to a similar domain in phosphatidylinositol-glycan-specific phospholipase D. Pssm-ID: 214549 [Multi-domain] Cd Length: 57 Bit Score: 72.02 E-value: 1.04e-15
|
||||||||||||
| Int_alpha | smart00191 | Integrin alpha (beta-propellor repeats); Integrins are cell adhesion molecules that mediate ... |
150-203 | 3.55e-11 | ||||||||
Integrin alpha (beta-propellor repeats); Integrins are cell adhesion molecules that mediate cell-extracellular matrix and cell-cell interactions. They contain both alpha and beta subunits. Alpha integrins are proposed to contain a domain containing a 7-fold repeat that adopts a beta-propellor fold. Some of these domains contain an inserted von Willebrand factor type-A domain. Some repeats contain putative calcium-binding sites. The 7-fold repeat domain is homologous to a similar domain in phosphatidylinositol-glycan-specific phospholipase D. Pssm-ID: 214549 [Multi-domain] Cd Length: 57 Bit Score: 59.31 E-value: 3.55e-11
|
||||||||||||
| FG-GAP | pfam01839 | FG-GAP repeat; This family contains the extracellular repeat that is found in up to seven ... |
152-190 | 1.05e-10 | ||||||||
FG-GAP repeat; This family contains the extracellular repeat that is found in up to seven copies in alpha integrins. This repeat has been predicted to fold into a beta propeller structure. The repeat is called the FG-GAP repeat after two conserved motifs in the repeat. The FG-GAP repeats are found in the N terminus of integrin alpha chains, a region that has been shown to be important for ligand binding. A putative Ca2+ binding motif is found in some of the repeats. Pssm-ID: 460357 Cd Length: 36 Bit Score: 57.14 E-value: 1.05e-10
|
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| FG-GAP_3 | pfam13517 | FG-GAP-like repeat; This entry represents a repeat found in alpha integrins and related ... |
160-233 | 1.35e-09 | ||||||||
FG-GAP-like repeat; This entry represents a repeat found in alpha integrins and related proteins in which form a 7-fold repeat that adopts a beta-propeller fold. This repeat contains a putative calcium-binding site. These repeats are found in multiple proteins from eukaryotes and bacteria and mediate diverse biological processes at both molecular and cellular levels, such as cell-cell interactions, host-pathogen recognition or innate immune responses. Pssm-ID: 433275 [Multi-domain] Cd Length: 61 Bit Score: 54.92 E-value: 1.35e-09
|
||||||||||||
| FG-GAP | pfam01839 | FG-GAP repeat; This family contains the extracellular repeat that is found in up to seven ... |
213-246 | 6.42e-08 | ||||||||
FG-GAP repeat; This family contains the extracellular repeat that is found in up to seven copies in alpha integrins. This repeat has been predicted to fold into a beta propeller structure. The repeat is called the FG-GAP repeat after two conserved motifs in the repeat. The FG-GAP repeats are found in the N terminus of integrin alpha chains, a region that has been shown to be important for ligand binding. A putative Ca2+ binding motif is found in some of the repeats. Pssm-ID: 460357 Cd Length: 36 Bit Score: 49.43 E-value: 6.42e-08
|
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| FG-GAP_3 | pfam13517 | FG-GAP-like repeat; This entry represents a repeat found in alpha integrins and related ... |
222-291 | 4.84e-06 | ||||||||
FG-GAP-like repeat; This entry represents a repeat found in alpha integrins and related proteins in which form a 7-fold repeat that adopts a beta-propeller fold. This repeat contains a putative calcium-binding site. These repeats are found in multiple proteins from eukaryotes and bacteria and mediate diverse biological processes at both molecular and cellular levels, such as cell-cell interactions, host-pathogen recognition or innate immune responses. Pssm-ID: 433275 [Multi-domain] Cd Length: 61 Bit Score: 44.91 E-value: 4.84e-06
|
||||||||||||
| Int_alpha | smart00191 | Integrin alpha (beta-propellor repeats); Integrins are cell adhesion molecules that mediate ... |
271-311 | 8.80e-06 | ||||||||
Integrin alpha (beta-propellor repeats); Integrins are cell adhesion molecules that mediate cell-extracellular matrix and cell-cell interactions. They contain both alpha and beta subunits. Alpha integrins are proposed to contain a domain containing a 7-fold repeat that adopts a beta-propellor fold. Some of these domains contain an inserted von Willebrand factor type-A domain. Some repeats contain putative calcium-binding sites. The 7-fold repeat domain is homologous to a similar domain in phosphatidylinositol-glycan-specific phospholipase D. Pssm-ID: 214549 [Multi-domain] Cd Length: 57 Bit Score: 43.90 E-value: 8.80e-06
|
||||||||||||
| Int_alpha | smart00191 | Integrin alpha (beta-propellor repeats); Integrins are cell adhesion molecules that mediate ... |
92-143 | 1.04e-04 | ||||||||
Integrin alpha (beta-propellor repeats); Integrins are cell adhesion molecules that mediate cell-extracellular matrix and cell-cell interactions. They contain both alpha and beta subunits. Alpha integrins are proposed to contain a domain containing a 7-fold repeat that adopts a beta-propellor fold. Some of these domains contain an inserted von Willebrand factor type-A domain. Some repeats contain putative calcium-binding sites. The 7-fold repeat domain is homologous to a similar domain in phosphatidylinositol-glycan-specific phospholipase D. Pssm-ID: 214549 [Multi-domain] Cd Length: 57 Bit Score: 40.82 E-value: 1.04e-04
|
||||||||||||
| FG-GAP_3 | pfam13517 | FG-GAP-like repeat; This entry represents a repeat found in alpha integrins and related ... |
121-171 | 8.77e-03 | ||||||||
FG-GAP-like repeat; This entry represents a repeat found in alpha integrins and related proteins in which form a 7-fold repeat that adopts a beta-propeller fold. This repeat contains a putative calcium-binding site. These repeats are found in multiple proteins from eukaryotes and bacteria and mediate diverse biological processes at both molecular and cellular levels, such as cell-cell interactions, host-pathogen recognition or innate immune responses. Pssm-ID: 433275 [Multi-domain] Cd Length: 61 Bit Score: 35.66 E-value: 8.77e-03
|
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| Blast search parameters | ||||
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