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Conserved domains on  [gi|1907091777|ref|XP_036013687|]
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uncharacterized protein LOC100041979 isoform X3 [Mus musculus]

Protein Classification

C2H2-type zinc finger protein( domain architecture ID 11472214)

Cys2His2 (C2H2)-type zinc finger protein may be involved in transcriptional regulation

CATH:  3.30.160.60
Gene Ontology:  GO:0008270|GO:0003677
PubMed:  11361095|22803940
SCOP:  4003583

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
16-415 3.23e-14

FOG: Zn-finger [General function prediction only];


:

Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 73.96  E-value: 3.23e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907091777  16 KPYKCNQCDKAFSQYNNLQTHRRTHTGEKPYKCNQ--CDKAFSQHSTLQTHRRTHTGEKPFKCN-QCDKAFSEKCSLQTH 92
Cdd:COG5048    32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYsgCDKSFSRPLELSRHLRTHHNNPSDLNSkSLPLSNSKASSSSLS 111

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907091777  93 RRTHTGEKPYKCNQCDKAFSQYSHLHIHRRTHTgeKPLKCNECDETFSNHSNLQTHRRIHTGEKPYKCNQCDKAFSQHSt 172
Cdd:COG5048   112 SSSSNSNDNNLLSSHSLPPSSRDPQLPDLLSIS--NLRNNPLPGNNSSSVNTPQSNSLHPPLPANSLSKDPSSNLSLLI- 188

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907091777 173 lqnHRRTHTGEKPFKCNQCDKAFSRHSTLQTHRRTHTGEKPFKCNQCDKAF------SQYSHLHIHRRTHTGEKPFKCNQ 246
Cdd:COG5048   189 ---SSNVSTSIPSSSENSPLSSSYSIPSSSSDQNLENSSSSLPLTTNSQLSpksllsQSPSSLSSSDSSSSASESPRSSL 265

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907091777 247 CNKAFSQYSHLHIHRRTHTG-EKPYKCNQCDKTFSNHSTLQTHRRT--HTGE--KPYKC--NQCDKAFSRHSTLQTHRRT 319
Cdd:COG5048   266 PTASSQSSSPNESDSSSEKGfSLPIKSKQCNISFSRSSPLTRHLRSvnHSGEslKPFSCpySLCGKLFSRNDALKRHILL 345

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907091777 320 HTGEKPFKC--NQCDKAFSQK------CSLQKHIRIHTGEKLYKC-NECDKAFSQHSTLQTHRRTHTGEKP--FKFNECD 388
Cdd:COG5048   346 HTSISPAKEklLNSSSKFSPLlnneppQSLQQYKDLKNDKKSETLsNSCIRNFKRDSNLSLHIITHLSFRPynCKNPPCS 425

                         410       420
                  ....*....|....*....|....*..
gi 1907091777 389 EGFSHHYNLQIHERRHTREKPYKCIQC 415
Cdd:COG5048   426 KSFNRHYNLIPHKKIHTNHAPLLCSIL 452
 
Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
16-415 3.23e-14

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 73.96  E-value: 3.23e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907091777  16 KPYKCNQCDKAFSQYNNLQTHRRTHTGEKPYKCNQ--CDKAFSQHSTLQTHRRTHTGEKPFKCN-QCDKAFSEKCSLQTH 92
Cdd:COG5048    32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYsgCDKSFSRPLELSRHLRTHHNNPSDLNSkSLPLSNSKASSSSLS 111

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907091777  93 RRTHTGEKPYKCNQCDKAFSQYSHLHIHRRTHTgeKPLKCNECDETFSNHSNLQTHRRIHTGEKPYKCNQCDKAFSQHSt 172
Cdd:COG5048   112 SSSSNSNDNNLLSSHSLPPSSRDPQLPDLLSIS--NLRNNPLPGNNSSSVNTPQSNSLHPPLPANSLSKDPSSNLSLLI- 188

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907091777 173 lqnHRRTHTGEKPFKCNQCDKAFSRHSTLQTHRRTHTGEKPFKCNQCDKAF------SQYSHLHIHRRTHTGEKPFKCNQ 246
Cdd:COG5048   189 ---SSNVSTSIPSSSENSPLSSSYSIPSSSSDQNLENSSSSLPLTTNSQLSpksllsQSPSSLSSSDSSSSASESPRSSL 265

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907091777 247 CNKAFSQYSHLHIHRRTHTG-EKPYKCNQCDKTFSNHSTLQTHRRT--HTGE--KPYKC--NQCDKAFSRHSTLQTHRRT 319
Cdd:COG5048   266 PTASSQSSSPNESDSSSEKGfSLPIKSKQCNISFSRSSPLTRHLRSvnHSGEslKPFSCpySLCGKLFSRNDALKRHILL 345

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907091777 320 HTGEKPFKC--NQCDKAFSQK------CSLQKHIRIHTGEKLYKC-NECDKAFSQHSTLQTHRRTHTGEKP--FKFNECD 388
Cdd:COG5048   346 HTSISPAKEklLNSSSKFSPLlnneppQSLQQYKDLKNDKKSETLsNSCIRNFKRDSNLSLHIITHLSFRPynCKNPPCS 425

                         410       420
                  ....*....|....*....|....*..
gi 1907091777 389 EGFSHHYNLQIHERRHTREKPYKCIQC 415
Cdd:COG5048   426 KSFNRHYNLIPHKKIHTNHAPLLCSIL 452
zf-H2C2_2 pfam13465
Zinc-finger double domain;
5-29 1.88e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 35.42  E-value: 1.88e-03
                          10        20
                  ....*....|....*....|....*
gi 1907091777   5 LKRHERFHTGEKPYKCNQCDKAFSQ 29
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
 
Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
16-415 3.23e-14

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 73.96  E-value: 3.23e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907091777  16 KPYKCNQCDKAFSQYNNLQTHRRTHTGEKPYKCNQ--CDKAFSQHSTLQTHRRTHTGEKPFKCN-QCDKAFSEKCSLQTH 92
Cdd:COG5048    32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYsgCDKSFSRPLELSRHLRTHHNNPSDLNSkSLPLSNSKASSSSLS 111

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907091777  93 RRTHTGEKPYKCNQCDKAFSQYSHLHIHRRTHTgeKPLKCNECDETFSNHSNLQTHRRIHTGEKPYKCNQCDKAFSQHSt 172
Cdd:COG5048   112 SSSSNSNDNNLLSSHSLPPSSRDPQLPDLLSIS--NLRNNPLPGNNSSSVNTPQSNSLHPPLPANSLSKDPSSNLSLLI- 188

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907091777 173 lqnHRRTHTGEKPFKCNQCDKAFSRHSTLQTHRRTHTGEKPFKCNQCDKAF------SQYSHLHIHRRTHTGEKPFKCNQ 246
Cdd:COG5048   189 ---SSNVSTSIPSSSENSPLSSSYSIPSSSSDQNLENSSSSLPLTTNSQLSpksllsQSPSSLSSSDSSSSASESPRSSL 265

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907091777 247 CNKAFSQYSHLHIHRRTHTG-EKPYKCNQCDKTFSNHSTLQTHRRT--HTGE--KPYKC--NQCDKAFSRHSTLQTHRRT 319
Cdd:COG5048   266 PTASSQSSSPNESDSSSEKGfSLPIKSKQCNISFSRSSPLTRHLRSvnHSGEslKPFSCpySLCGKLFSRNDALKRHILL 345

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907091777 320 HTGEKPFKC--NQCDKAFSQK------CSLQKHIRIHTGEKLYKC-NECDKAFSQHSTLQTHRRTHTGEKP--FKFNECD 388
Cdd:COG5048   346 HTSISPAKEklLNSSSKFSPLlnneppQSLQQYKDLKNDKKSETLsNSCIRNFKRDSNLSLHIITHLSFRPynCKNPPCS 425

                         410       420
                  ....*....|....*....|....*..
gi 1907091777 389 EGFSHHYNLQIHERRHTREKPYKCIQC 415
Cdd:COG5048   426 KSFNRHYNLIPHKKIHTNHAPLLCSIL 452
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
88-337 1.91e-07

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 53.16  E-value: 1.91e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907091777  88 SLQTHRRTHTGEKPYKCNQCDKAFSQYSHLHIHRRTHTGEKPLKCNECDETFSNHSNLQTHRRI------HTGEKPYKCN 161
Cdd:COG5048   185 SLLISSNVSTSIPSSSENSPLSSSYSIPSSSSDQNLENSSSSLPLTTNSQLSPKSLLSQSPSSLsssdssSSASESPRSS 264

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907091777 162 QCDKAFSQHSTLQNHRRTHTG-EKPFKCNQCDKAFSRHSTLQTHRRT--HTGE--KPFKC--NQCDKAFSQYSHLHIHRR 234
Cdd:COG5048   265 LPTASSQSSSPNESDSSSEKGfSLPIKSKQCNISFSRSSPLTRHLRSvnHSGEslKPFSCpySLCGKLFSRNDALKRHIL 344

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907091777 235 THTGEKPFKC--NQCNKAFSQYSH-----LHIHRRTHTGEKPYKC--NQCDKTFSNHSTLQTHRRTHTGEKP--YKCNQC 303
Cdd:COG5048   345 LHTSISPAKEklLNSSSKFSPLLNneppqSLQQYKDLKNDKKSETlsNSCIRNFKRDSNLSLHIITHLSFRPynCKNPPC 424

                         250       260       270
                  ....*....|....*....|....*....|....
gi 1907091777 304 DKAFSRHSTLQTHRRTHTGEKPFKCNQCDKAFSQ 337
Cdd:COG5048   425 SKSFNRHYNLIPHKKIHTNHAPLLCSILKSFRRD 458
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
28-225 2.55e-05

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 46.23  E-value: 2.55e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907091777  28 SQYNNLQTHRRTHTGEKPYKCNQcDKAFSQHSTLQTHRRTHTG-EKPFKCNQCDKAFSEKCSLQTHRRT--HTGE--KPY 102
Cdd:COG5048   244 SPSSLSSSDSSSSASESPRSSLP-TASSQSSSPNESDSSSEKGfSLPIKSKQCNISFSRSSPLTRHLRSvnHSGEslKPF 322

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907091777 103 KC--NQCDKAFSQYSHLHIHRRTHTGEKPLKCNECDETFS--------NHSNLQTHRRIHTGEKPYKC-NQCDKAFSQHS 171
Cdd:COG5048   323 SCpySLCGKLFSRNDALKRHILLHTSISPAKEKLLNSSSKfspllnnePPQSLQQYKDLKNDKKSETLsNSCIRNFKRDS 402

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 1907091777 172 TLQNHRRTHTGEKP--FKCNQCDKAFSRHSTLQTHRRTHTGEKPFKCNQCDKAFSQ 225
Cdd:COG5048   403 NLSLHIITHLSFRPynCKNPPCSKSFNRHYNLIPHKKIHTNHAPLLCSILKSFRRD 458
zf-H2C2_2 pfam13465
Zinc-finger double domain;
5-29 1.88e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 35.42  E-value: 1.88e-03
                          10        20
                  ....*....|....*....|....*
gi 1907091777   5 LKRHERFHTGEKPYKCNQCDKAFSQ 29
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
32-57 2.45e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 35.04  E-value: 2.45e-03
                          10        20
                  ....*....|....*....|....*.
gi 1907091777  32 NLQTHRRTHTGEKPYKCNQCDKAFSQ 57
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
144-169 2.73e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 35.04  E-value: 2.73e-03
                          10        20
                  ....*....|....*....|....*.
gi 1907091777 144 NLQTHRRIHTGEKPYKCNQCDKAFSQ 169
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 42-125 3.85e-03

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 39.32  E-value: 3.85e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907091777  42 GEKPYKCN--QCDKAFSQHSTLQTHRrthtgekpfKCNQCDKAFSEKCSLQTHRRTHTGEKPYKCNQCDKAFSQYSHLHI 119
Cdd:COG5189   346 DGKPYKCPveGCNKKYKNQNGLKYHM---------LHGHQNQKLHENPSPEKMNIFSAKDKPYRCEVCDKRYKNLNGLKY 416


                  ....*.
gi 1907091777 120 HRRTHT 125
Cdd:COG5189   417 HRKHSH 422
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 239-321 4.67e-03

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 38.93  E-value: 4.67e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907091777 239 EKPFKCNQCNKAFSQYSHLHIH---RRTHT-GEKPYKCN--QCDKTFSNHSTLQTHR-------RTH------------T 293
Cdd:COG5189   315 KLPCTNSSSNGKLAHGGERNIDtpsRMLKVkDGKPYKCPveGCNKKYKNQNGLKYHMlhghqnqKLHenpspekmnifsA 394

                          90       100
                  ....*....|....*....|....*...
gi 1907091777 294 GEKPYKCNQCDKAFSRHSTLQTHRRTHT 321
Cdd:COG5189   395 KDKPYRCEVCDKRYKNLNGLKYHRKHSH 422
zf-H2C2_2 pfam13465
Zinc-finger double domain;
88-113 4.83e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 34.27  E-value: 4.83e-03
                          10        20
                  ....*....|....*....|....*.
gi 1907091777  88 SLQTHRRTHTGEKPYKCNQCDKAFSQ 113
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
 238-293 5.71e-03

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 38.93  E-value: 5.71e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1907091777 238 GEKPFKCN--QCNKAFS-----QYSHLHIHRRTHTGE--------------KPYKCNQCDKTFSNHSTLQTHRRTHT 293
Cdd:COG5189   346 DGKPYKCPveGCNKKYKnqnglKYHMLHGHQNQKLHEnpspekmnifsakdKPYRCEVCDKRYKNLNGLKYHRKHSH 422
zf-H2C2_2 pfam13465
Zinc-finger double domain;
285-309 6.36e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 33.88  E-value: 6.36e-03
                          10        20
                  ....*....|....*....|....*
gi 1907091777 285 LQTHRRTHTGEKPYKCNQCDKAFSR 309
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
201-225 6.82e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 33.88  E-value: 6.82e-03
                          10        20
                  ....*....|....*....|....*
gi 1907091777 201 LQTHRRTHTGEKPFKCNQCDKAFSQ 225
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
313-337 6.82e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 33.88  E-value: 6.82e-03
                          10        20
                  ....*....|....*....|....*
gi 1907091777 313 LQTHRRTHTGEKPFKCNQCDKAFSQ 337
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
173-197 7.30e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 33.88  E-value: 7.30e-03
                          10        20
                  ....*....|....*....|....*
gi 1907091777 173 LQNHRRTHTGEKPFKCNQCDKAFSR 197
Cdd:pfam13465   2 LKRHMRTHTGEKPYKCPECGKSFKS 26
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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