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Conserved domains on  [gi|1907093718|ref|XP_036013929|]
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zinc finger protein 124 isoform X1 [Mus musculus]

Protein Classification

C2H2-type zinc finger protein (domain architecture ID 11472214)

Cys2His2 (C2H2)-type zinc finger protein may be involved in transcriptional regulation

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
69-221 1.55e-07

FOG: Zn-finger [General function prediction only];


:

Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 51.24  E-value: 1.55e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907093718  69 KPYECNQCGKAFSQHSRLQYHKRS--HTGE--KPYKC--NQCGKAYGHHSSLQYHKRRHTGEKPYHC--NQCDKAFS--- 137
Cdd:COG5048   288 LPIKSKQCNISFSRSSPLTRHLRSvnHSGEslKPFSCpySLCGKLFSRNDALKRHILLHTSISPAKEklLNSSSKFSpll 367
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907093718 138 --EHSSLEYHKITHLGEKPYECD--QCGKAFAWQSSLNIHKRTHSGEKPYECN--ECGKAFTHHASLQSHKRIHTGEKPY 211
Cdd:COG5048   368 nnEPPQSLQQYKDLKNDKKSETLsnSCIRNFKRDSNLSLHIITHLSFRPYNCKnpPCSKSFNRHYNLIPHKKIHTNHAPL 447
                         170
                  ....*....|
gi 1907093718 212 QCDQCGKAFA 221
Cdd:COG5048   448 LCSILKSFRR 457
 
Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
69-221 1.55e-07

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 51.24  E-value: 1.55e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907093718  69 KPYECNQCGKAFSQHSRLQYHKRS--HTGE--KPYKC--NQCGKAYGHHSSLQYHKRRHTGEKPYHC--NQCDKAFS--- 137
Cdd:COG5048   288 LPIKSKQCNISFSRSSPLTRHLRSvnHSGEslKPFSCpySLCGKLFSRNDALKRHILLHTSISPAKEklLNSSSKFSpll 367
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907093718 138 --EHSSLEYHKITHLGEKPYECD--QCGKAFAWQSSLNIHKRTHSGEKPYECN--ECGKAFTHHASLQSHKRIHTGEKPY 211
Cdd:COG5048   368 nnEPPQSLQQYKDLKNDKKSETLsnSCIRNFKRDSNLSLHIITHLSFRPYNCKnpPCSKSFNRHYNLIPHKKIHTNHAPL 447
                         170
                  ....*....|
gi 1907093718 212 QCDQCGKAFA 221
Cdd:COG5048   448 LCSILKSFRR 457
zf-H2C2_2 pfam13465
Zinc-finger double domain;
197-222 4.06e-04

Zinc-finger double domain;


Pssm-ID: 404364 [Multi-domain]  Cd Length: 26  Bit Score: 36.56  E-value: 4.06e-04
                          10        20
                  ....*....|....*....|....*.
gi 1907093718 197 SLQSHKRIHTGEKPYQCDQCGKAFAH 222
Cdd:pfam13465   1 NLKRHMRKHTGEKPYKCPECGKSFKS 26
 
Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
69-221 1.55e-07

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 51.24  E-value: 1.55e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907093718  69 KPYECNQCGKAFSQHSRLQYHKRS--HTGE--KPYKC--NQCGKAYGHHSSLQYHKRRHTGEKPYHC--NQCDKAFS--- 137
Cdd:COG5048   288 LPIKSKQCNISFSRSSPLTRHLRSvnHSGEslKPFSCpySLCGKLFSRNDALKRHILLHTSISPAKEklLNSSSKFSpll 367
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907093718 138 --EHSSLEYHKITHLGEKPYECD--QCGKAFAWQSSLNIHKRTHSGEKPYECN--ECGKAFTHHASLQSHKRIHTGEKPY 211
Cdd:COG5048   368 nnEPPQSLQQYKDLKNDKKSETLsnSCIRNFKRDSNLSLHIITHLSFRPYNCKnpPCSKSFNRHYNLIPHKKIHTNHAPL 447
                         170
                  ....*....|
gi 1907093718 212 QCDQCGKAFA 221
Cdd:COG5048   448 LCSILKSFRR 457
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
84-178 2.29e-06

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 47.79  E-value: 2.29e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907093718  84 SRLQYHKrshtGEKPYKCN--QCGKAYGHHSSLQYHKrrhtgeKPYHCNQcdkAFSEHSSLEYHKITHLGEKPYECDQCG 161
Cdd:COG5189   339 SRMLKVK----DGKPYKCPveGCNKKYKNQNGLKYHM------LHGHQNQ---KLHENPSPEKMNIFSAKDKPYRCEVCD 405
                          90
                  ....*....|....*..
gi 1907093718 162 KAFAWQSSLNIHkRTHS 178
Cdd:COG5189   406 KRYKNLNGLKYH-RKHS 421
zf-H2C2_2 pfam13465
Zinc-finger double domain;
197-222 4.06e-04

Zinc-finger double domain;


Pssm-ID: 404364 [Multi-domain]  Cd Length: 26  Bit Score: 36.56  E-value: 4.06e-04
                          10        20
                  ....*....|....*....|....*.
gi 1907093718 197 SLQSHKRIHTGEKPYQCDQCGKAFAH 222
Cdd:pfam13465   1 NLKRHMRKHTGEKPYKCPECGKSFKS 26
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
32-122 5.20e-04

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 40.47  E-value: 5.20e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907093718  32 RHERIHIGEKPYERNQCGKAFASDNHLQI----HKRTNTEEKPYECN--QCGKAFSQHSRLQYHKR-------------- 91
Cdd:COG5189   307 TGEMIDVRKLPCTNSSSNGKLAHGGERNIdtpsRMLKVKDGKPYKCPveGCNKKYKNQNGLKYHMLhghqnqklhenpsp 386
                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 1907093718  92 -SHTG----EKPYKCNQCGKAYGHHSSLQYHKRRHT 122
Cdd:COG5189   387 eKMNIfsakDKPYRCEVCDKRYKNLNGLKYHRKHSH 422
zf-H2C2_2 pfam13465
Zinc-finger double domain;
113-137 2.00e-03

Zinc-finger double domain;


Pssm-ID: 404364 [Multi-domain]  Cd Length: 26  Bit Score: 34.63  E-value: 2.00e-03
                          10        20
                  ....*....|....*....|....*
gi 1907093718 113 SLQYHKRRHTGEKPYHCNQCDKAFS 137
Cdd:pfam13465   1 NLKRHMRKHTGEKPYKCPECGKSFK 25
SFP1 COG5189
Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division ...
150-234 3.25e-03

Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning];


Pssm-ID: 227516 [Multi-domain]  Cd Length: 423  Bit Score: 38.16  E-value: 3.25e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907093718 150 LGEKPYECD--QCGKAFAWQSSLNIHKRThsgekpyecNECGKAFTHHASLQSHKRIHTGEKPYQCDQCGKAFAHQTSLQ 227
Cdd:COG5189   345 KDGKPYKCPveGCNKKYKNQNGLKYHMLH---------GHQNQKLHENPSPEKMNIFSAKDKPYRCEVCDKRYKNLNGLK 415

                  ....*..
gi 1907093718 228 CHkRTHT 234
Cdd:COG5189   416 YH-RKHS 421
zf-H2C2_2 pfam13465
Zinc-finger double domain;
169-194 5.20e-03

Zinc-finger double domain;


Pssm-ID: 404364 [Multi-domain]  Cd Length: 26  Bit Score: 33.48  E-value: 5.20e-03
                          10        20
                  ....*....|....*....|....*.
gi 1907093718 169 SLNIHKRTHSGEKPYECNECGKAFTH 194
Cdd:pfam13465   1 NLKRHMRKHTGEKPYKCPECGKSFKS 26
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
65-242 5.30e-03

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 37.37  E-value: 5.30e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907093718  65 NTEEKPYECNQCGKAFSQHSRLQYHKRSHTG-EKPYKCNQCGKAYGHHSSLQYHKR--RHTGE--KPYHC--NQCDKAFS 137
Cdd:COG5048   255 SSASESPRSSLPTASSQSSSPNESDSSSEKGfSLPIKSKQCNISFSRSSPLTRHLRsvNHSGEslKPFSCpySLCGKLFS 334
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907093718 138 EHSSLEYHKITHLGEKPYEC--DQCGKAF-----AWQSSLNIHKRTHSGEKPYEC--NECGKAFTHHASLQSHKRIHTGE 208
Cdd:COG5048   335 RNDALKRHILLHTSISPAKEklLNSSSKFspllnNEPPQSLQQYKDLKNDKKSETlsNSCIRNFKRDSNLSLHIITHLSF 414
                         170       180       190
                  ....*....|....*....|....*....|....*.
gi 1907093718 209 KPYQCD--QCGKAFAHQTSLQCHKRTHTGEKPYECN 242
Cdd:COG5048   415 RPYNCKnpPCSKSFNRHYNLIPHKKIHTNHAPLLCS 450
zf-H2C2_2 pfam13465
Zinc-finger double domain;
85-110 7.63e-03

Zinc-finger double domain;


Pssm-ID: 404364 [Multi-domain]  Cd Length: 26  Bit Score: 33.09  E-value: 7.63e-03
                          10        20
                  ....*....|....*....|....*.
gi 1907093718  85 RLQYHKRSHTGEKPYKCNQCGKAYGH 110
Cdd:pfam13465   1 NLKRHMRKHTGEKPYKCPECGKSFKS 26
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.19
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
  • Marchler-Bauer A et al. (2015), "CDD: NCBI's conserved domain database.", Nucleic Acids Res.43(D)222-6.
  • Marchler-Bauer A et al. (2011), "CDD: a Conserved Domain Database for the functional annotation of proteins.", Nucleic Acids Res.39(D)225-9.
  • Marchler-Bauer A, Bryant SH (2004), "CD-Search: protein domain annotations on the fly.", Nucleic Acids Res.32(W)327-331.
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