|
Name |
Accession |
Description |
Interval |
E-value |
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
172-483 |
2.16e-27 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 113.47 E-value: 2.16e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907206266 172 DEAVPRVRFANDDRhRLACCSLDGSISLCQLvpAPPTVLHVLRGHTRGVSDFAWSLSNDILVSTSLDATMRIWASEDGRC 251
Cdd:COG2319 120 TGAVRSVAFSPDGK-TLASGSADGTVRLWDL--ATGKLLRTLTGHSGAVTSVAFSPDGKLLASGSDDGTVRLWDLATGKL 196
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907206266 252 IREIPDPDGAeLLCCTFQPvNNNLTVVGNAKHNVHVMNISTGKKVK--GGSsklTGRVLALSFDAPGRLLWAGDDRGSVf 329
Cdd:COG2319 197 LRTLTGHTGA-VRSVAFSP-DGKLLASGSADGTVRLWDLATGKLLRtlTGH---SGSVRSVAFSPDGRLLASGSADGTV- 270
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907206266 330 sFLFDMATGKLtkaKRLVVHEGSPVTSISArswvsreARDPSLLINACLNKLLlyRVVDNEGALQLKrsfPIEQSSHPVR 409
Cdd:COG2319 271 -RLWDLATGEL---LRTLTGHSGGVNSVAF-------SPDGKLLASGSDDGTV--RLWDLATGKLLR---TLTGHTGAVR 334
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1907206266 410 SI-FCPlmsfrQGACVVTGSEDMCVHFFDVerAAKAAVNKLQGHSAPVLDVSFNCDESLLASSDASGMVIVWRRE 483
Cdd:COG2319 335 SVaFSP-----DGKTLASGSDDGTVRLWDL--ATGELLRTLTGHTGAVTSVAFSPDGRTLASGSADGTVRLWDLA 402
|
|
| WD40 |
cd00200 |
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
175-481 |
1.40e-19 |
|
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.
Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 88.93 E-value: 1.40e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907206266 175 VPRVRFaNDDRHRLACCSLDGSISLCQLvpAPPTVLHVLRGHTRGVSDFAWSLSNDILVSTSLDATMRIWASEDGRCIRE 254
Cdd:cd00200 12 VTCVAF-SPDGKLLATGSGDGTIKVWDL--ETGELLRTLKGHTGPVRDVAASADGTYLASGSSDKTIRLWDLETGECVRT 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907206266 255 IPDpDGAELLCCTFQPvNNNLTVVGNAKHNVHVMNISTGKKVKGGSSKlTGRVLALSFDAPGRLLWAGDDRGSVfsFLFD 334
Cdd:cd00200 89 LTG-HTSYVSSVAFSP-DGRILSSSSRDKTIKVWDVETGKCLTTLRGH-TDWVNSVAFSPDGTFVASSSQDGTI--KLWD 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907206266 335 MATGKLTkaKRLVVHEGsPVTSISARSwvsrearDPSLLINACLNKLLlyRVVDNEGALQLKRsfpIEQSSHPVRSI-FC 413
Cdd:cd00200 164 LRTGKCV--ATLTGHTG-EVNSVAFSP-------DGEKLLSSSSDGTI--KLWDLSTGKCLGT---LRGHENGVNSVaFS 228
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1907206266 414 PLMSFrqgacVVTGSEDMCVHFFDVEraAKAAVNKLQGHSAPVLDVSFNCDESLLASSDASGMVIVWR 481
Cdd:cd00200 229 PDGYL-----LASGSEDGTIRVWDLR--TGECVQTLSGHTNSVTSLAWSPDGKRLASGSADGTIRIWD 289
|
|
| WD40 |
smart00320 |
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ... |
206-244 |
2.28e-06 |
|
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.
Pssm-ID: 197651 [Multi-domain] Cd Length: 40 Bit Score: 44.23 E-value: 2.28e-06
10 20 30
....*....|....*....|....*....|....*....
gi 1907206266 206 PPTVLHVLRGHTRGVSDFAWSLSNDILVSTSLDATMRIW 244
Cdd:smart00320 1 SGELLKTLKGHTGPVTSVAFSPDGKYLASGSDDGTIKLW 39
|
|
| WD40 |
pfam00400 |
WD domain, G-beta repeat; |
208-244 |
5.53e-06 |
|
WD domain, G-beta repeat;
Pssm-ID: 459801 [Multi-domain] Cd Length: 39 Bit Score: 43.10 E-value: 5.53e-06
10 20 30
....*....|....*....|....*....|....*..
gi 1907206266 208 TVLHVLRGHTRGVSDFAWSLSNDILVSTSLDATMRIW 244
Cdd:pfam00400 2 KLLKTLEGHTGSVTSLAFSPDGKLLASGSDDGTVKVW 38
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
172-483 |
2.16e-27 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 113.47 E-value: 2.16e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907206266 172 DEAVPRVRFANDDRhRLACCSLDGSISLCQLvpAPPTVLHVLRGHTRGVSDFAWSLSNDILVSTSLDATMRIWASEDGRC 251
Cdd:COG2319 120 TGAVRSVAFSPDGK-TLASGSADGTVRLWDL--ATGKLLRTLTGHSGAVTSVAFSPDGKLLASGSDDGTVRLWDLATGKL 196
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907206266 252 IREIPDPDGAeLLCCTFQPvNNNLTVVGNAKHNVHVMNISTGKKVK--GGSsklTGRVLALSFDAPGRLLWAGDDRGSVf 329
Cdd:COG2319 197 LRTLTGHTGA-VRSVAFSP-DGKLLASGSADGTVRLWDLATGKLLRtlTGH---SGSVRSVAFSPDGRLLASGSADGTV- 270
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907206266 330 sFLFDMATGKLtkaKRLVVHEGSPVTSISArswvsreARDPSLLINACLNKLLlyRVVDNEGALQLKrsfPIEQSSHPVR 409
Cdd:COG2319 271 -RLWDLATGEL---LRTLTGHSGGVNSVAF-------SPDGKLLASGSDDGTV--RLWDLATGKLLR---TLTGHTGAVR 334
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1907206266 410 SI-FCPlmsfrQGACVVTGSEDMCVHFFDVerAAKAAVNKLQGHSAPVLDVSFNCDESLLASSDASGMVIVWRRE 483
Cdd:COG2319 335 SVaFSP-----DGKTLASGSDDGTVRLWDL--ATGELLRTLTGHTGAVTSVAFSPDGRTLASGSADGTVRLWDLA 402
|
|
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
95-483 |
2.41e-22 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 98.83 E-value: 2.41e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907206266 95 DFEDDPRALGARGHRRSVSRGSYQLQAQMNRAVYEDRPPGSVVPTSVAEASRAMAGDTSLSENYAFAGMYHVFDQHVDEA 174
Cdd:COG2319 1 ALSADGAALAAASADLALALLAAALGALLLLLLGLAAAVASLAASPDGARLAAGAGDLTLLLLDAAAGALLATLLGHTAA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907206266 175 VPRVRFANDDRhRLACCSLDGSISLCQLvpAPPTVLHVLRGHTRGVSDFAWSLSNDILVSTSLDATMRIWASEDGRCIRE 254
Cdd:COG2319 81 VLSVAFSPDGR-LLASASADGTVRLWDL--ATGLLLRTLTGHTGAVRSVAFSPDGKTLASGSADGTVRLWDLATGKLLRT 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907206266 255 IPDPDGAeLLCCTFQPvNNNLTVVGNAKHNVHVMNISTGKKVKggssKLTG---RVLALSFDAPGRLLWAGDDRGSVfsF 331
Cdd:COG2319 158 LTGHSGA-VTSVAFSP-DGKLLASGSDDGTVRLWDLATGKLLR----TLTGhtgAVRSVAFSPDGKLLASGSADGTV--R 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907206266 332 LFDMATGKLTkakRLVVHEGSPVTSISarswVSreaRDPSLLINACLNKLLlyRVVDNEGALQLKRsfpIEQSSHPVRSI 411
Cdd:COG2319 230 LWDLATGKLL---RTLTGHSGSVRSVA----FS---PDGRLLASGSADGTV--RLWDLATGELLRT---LTGHSGGVNSV 294
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1907206266 412 -FCPlmsfrQGACVVTGSEDMCVHFFDVerAAKAAVNKLQGHSAPVLDVSFNCDESLLASSDASGMVIVWRRE 483
Cdd:COG2319 295 aFSP-----DGKLLASGSDDGTVRLWDL--ATGKLLRTLTGHTGAVRSVAFSPDGKTLASGSDDGTVRLWDLA 360
|
|
| WD40 |
cd00200 |
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
175-481 |
1.40e-19 |
|
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.
Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 88.93 E-value: 1.40e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907206266 175 VPRVRFaNDDRHRLACCSLDGSISLCQLvpAPPTVLHVLRGHTRGVSDFAWSLSNDILVSTSLDATMRIWASEDGRCIRE 254
Cdd:cd00200 12 VTCVAF-SPDGKLLATGSGDGTIKVWDL--ETGELLRTLKGHTGPVRDVAASADGTYLASGSSDKTIRLWDLETGECVRT 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907206266 255 IPDpDGAELLCCTFQPvNNNLTVVGNAKHNVHVMNISTGKKVKGGSSKlTGRVLALSFDAPGRLLWAGDDRGSVfsFLFD 334
Cdd:cd00200 89 LTG-HTSYVSSVAFSP-DGRILSSSSRDKTIKVWDVETGKCLTTLRGH-TDWVNSVAFSPDGTFVASSSQDGTI--KLWD 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907206266 335 MATGKLTkaKRLVVHEGsPVTSISARSwvsrearDPSLLINACLNKLLlyRVVDNEGALQLKRsfpIEQSSHPVRSI-FC 413
Cdd:cd00200 164 LRTGKCV--ATLTGHTG-EVNSVAFSP-------DGEKLLSSSSDGTI--KLWDLSTGKCLGT---LRGHENGVNSVaFS 228
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1907206266 414 PLMSFrqgacVVTGSEDMCVHFFDVEraAKAAVNKLQGHSAPVLDVSFNCDESLLASSDASGMVIVWR 481
Cdd:cd00200 229 PDGYL-----LASGSEDGTIRVWDLR--TGECVQTLSGHTNSVTSLAWSPDGKRLASGSADGTIRIWD 289
|
|
| WD40 |
cd00200 |
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
210-481 |
7.51e-19 |
|
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.
Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 86.62 E-value: 7.51e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907206266 210 LHVLRGHTRGVSDFAWSLSNDILVSTSLDATMRIWASEDGRCIREIPDPDGaELLCCTFQPVNNNLTVVGNAKhNVHVMN 289
Cdd:cd00200 2 RRTLKGHTGGVTCVAFSPDGKLLATGSGDGTIKVWDLETGELLRTLKGHTG-PVRDVAASADGTYLASGSSDK-TIRLWD 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907206266 290 ISTGKKVkggsSKLTG---RVLALSFDAPGRLL-WAGDDrGSVfsFLFDMATGKLTKAkrLVVHEGsPVTSISARSwvsr 365
Cdd:cd00200 80 LETGECV----RTLTGhtsYVSSVAFSPDGRILsSSSRD-KTI--KVWDVETGKCLTT--LRGHTD-WVNSVAFSP---- 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907206266 366 earDPSLLINACLNKLLlyRVVDNEgALQLKRSFPIEQSshPVRSI-FCPlmsfrQGACVVTGSEDMCVHFFDVerAAKA 444
Cdd:cd00200 146 ---DGTFVASSSQDGTI--KLWDLR-TGKCVATLTGHTG--EVNSVaFSP-----DGEKLLSSSSDGTIKLWDL--STGK 210
|
250 260 270
....*....|....*....|....*....|....*..
gi 1907206266 445 AVNKLQGHSAPVLDVSFNCDESLLASSDASGMVIVWR 481
Cdd:cd00200 211 CLGTLRGHENGVNSVAFSPDGYLLASGSEDGTIRVWD 247
|
|
| WD40 |
smart00320 |
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ... |
206-244 |
2.28e-06 |
|
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.
Pssm-ID: 197651 [Multi-domain] Cd Length: 40 Bit Score: 44.23 E-value: 2.28e-06
10 20 30
....*....|....*....|....*....|....*....
gi 1907206266 206 PPTVLHVLRGHTRGVSDFAWSLSNDILVSTSLDATMRIW 244
Cdd:smart00320 1 SGELLKTLKGHTGPVTSVAFSPDGKYLASGSDDGTIKLW 39
|
|
| WD40 |
pfam00400 |
WD domain, G-beta repeat; |
208-244 |
5.53e-06 |
|
WD domain, G-beta repeat;
Pssm-ID: 459801 [Multi-domain] Cd Length: 39 Bit Score: 43.10 E-value: 5.53e-06
10 20 30
....*....|....*....|....*....|....*..
gi 1907206266 208 TVLHVLRGHTRGVSDFAWSLSNDILVSTSLDATMRIW 244
Cdd:pfam00400 2 KLLKTLEGHTGSVTSLAFSPDGKLLASGSDDGTVKVW 38
|
|
| WD40 |
smart00320 |
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ... |
446-480 |
1.70e-05 |
|
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.
Pssm-ID: 197651 [Multi-domain] Cd Length: 40 Bit Score: 41.91 E-value: 1.70e-05
10 20 30
....*....|....*....|....*....|....*
gi 1907206266 446 VNKLQGHSAPVLDVSFNCDESLLASSDASGMVIVW 480
Cdd:smart00320 5 LKTLKGHTGPVTSVAFSPDGKYLASGSDDGTIKLW 39
|
|
| WD40 |
pfam00400 |
WD domain, G-beta repeat; |
446-480 |
1.32e-04 |
|
WD domain, G-beta repeat;
Pssm-ID: 459801 [Multi-domain] Cd Length: 39 Bit Score: 39.25 E-value: 1.32e-04
10 20 30
....*....|....*....|....*....|....*
gi 1907206266 446 VNKLQGHSAPVLDVSFNCDESLLASSDASGMVIVW 480
Cdd:pfam00400 4 LKTLEGHTGSVTSLAFSPDGKLLASGSDDGTVKVW 38
|
|
| YncE |
COG3391 |
DNA-binding beta-propeller fold protein YncE [General function prediction only]; |
166-342 |
1.58e-04 |
|
DNA-binding beta-propeller fold protein YncE [General function prediction only];
Pssm-ID: 442618 [Multi-domain] Cd Length: 237 Bit Score: 43.14 E-value: 1.58e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907206266 166 VFDQHVDEAVPRVRFANDDRHRLACCSLDGSISLCQLVPAPPTVLHVLRGHTRGVSDFAWSLSNDIL-VSTSLDATMRIW 244
Cdd:COG3391 16 LALAALAVAVAALGLGGGGPLLAAASGGVVGAAVGGGGVALLAGLGLGAAAVADADGADAGADGRRLyVANSGSGRVSVI 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1907206266 245 ASEDGRCIREIPDPDGAELLCctFQPVNNNLTVVGNAKHNVHVMNISTGKKVKggSSKLTGRVLALSFDAPGRLLW---A 321
Cdd:COG3391 96 DLATGKVVATIPVGGGPRGLA--VDPDGGRLYVADSGNGRVSVIDTATGKVVA--TIPVGAGPHGIAVDPDGKRLYvanS 171
|
170 180
....*....|....*....|.
gi 1907206266 322 GDDRGSVFSFLFDMATGKLTK 342
Cdd:COG3391 172 GSNTVSVIVSVIDTATGKVVA 192
|
|
| WD40 |
cd00200 |
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
424-484 |
3.86e-03 |
|
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.
Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 39.24 E-value: 3.86e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1907206266 424 VVTGSEDMCVHFFDVERAAKaaVNKLQGHSAPVLDVSFNCDESLLASSDASGMVIVWRREQ 484
Cdd:cd00200 24 LATGSGDGTIKVWDLETGEL--LRTLKGHTGPVRDVAASADGTYLASGSSDKTIRLWDLET 82
|
|
| |
