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Conserved domains on  [gi|1907143660|ref|XP_036018526|]
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acyl-CoA-binding domain-containing protein 5 isoform X4 [Mus musculus]

Protein Classification

acyl-CoA-binding protein( domain architecture ID 1012)

acyl-CoA-binding protein binds acyl-CoA esters and may play a role in housekeeping and/or trafficking

CATH:  1.20.80.10
Gene Ontology:  GO:0000062
PubMed:  16018771
SCOP:  4000745

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
ACBP super family cl00221
Acyl CoA binding protein (ACBP) binds thiol esters of long fatty acids and coenzyme A in a ...
1-22 2.60e-03

Acyl CoA binding protein (ACBP) binds thiol esters of long fatty acids and coenzyme A in a one-to-one binding mode with high specificity and affinity. Acyl-CoAs are important intermediates in fatty lipid synthesis and fatty acid degradation and play a role in regulation of intermediary metabolism and gene regulation. The suggested role of ACBP is to act as a intracellular acyl-CoA transporter and pool former. ACBPs are present in a large group of eukaryotic species and several tissue-specific isoforms have been detected.


The actual alignment was detected with superfamily member cd00435:

Pssm-ID: 444761  Cd Length: 85  Bit Score: 36.53  E-value: 2.60e-03
                          10        20
                  ....*....|....*....|..
gi 1907143660   1 MTKEEAMIAYVEEMKKIIETMP 22
Cdd:cd00435    64 MSKEDAMKAYIAKVEELIAKYA 85
 
Name Accession Description Interval E-value
ACBP cd00435
Acyl CoA binding protein (ACBP) binds thiol esters of long fatty acids and coenzyme A in a ...
1-22 2.60e-03

Acyl CoA binding protein (ACBP) binds thiol esters of long fatty acids and coenzyme A in a one-to-one binding mode with high specificity and affinity. Acyl-CoAs are important intermediates in fatty lipid synthesis and fatty acid degradation and play a role in regulation of intermediary metabolism and gene regulation. The suggested role of ACBP is to act as a intracellular acyl-CoA transporter and pool former. ACBPs are present in a large group of eukaryotic species and several tissue-specific isoforms have been detected.


Pssm-ID: 238248  Cd Length: 85  Bit Score: 36.53  E-value: 2.60e-03
                          10        20
                  ....*....|....*....|..
gi 1907143660   1 MTKEEAMIAYVEEMKKIIETMP 22
Cdd:cd00435    64 MSKEDAMKAYIAKVEELIAKYA 85
 
Name Accession Description Interval E-value
ACBP cd00435
Acyl CoA binding protein (ACBP) binds thiol esters of long fatty acids and coenzyme A in a ...
1-22 2.60e-03

Acyl CoA binding protein (ACBP) binds thiol esters of long fatty acids and coenzyme A in a one-to-one binding mode with high specificity and affinity. Acyl-CoAs are important intermediates in fatty lipid synthesis and fatty acid degradation and play a role in regulation of intermediary metabolism and gene regulation. The suggested role of ACBP is to act as a intracellular acyl-CoA transporter and pool former. ACBPs are present in a large group of eukaryotic species and several tissue-specific isoforms have been detected.


Pssm-ID: 238248  Cd Length: 85  Bit Score: 36.53  E-value: 2.60e-03
                          10        20
                  ....*....|....*....|..
gi 1907143660   1 MTKEEAMIAYVEEMKKIIETMP 22
Cdd:cd00435    64 MSKEDAMKAYIAKVEELIAKYA 85
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.20
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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