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Conserved domains on  [gi|1907165361|ref|XP_036021269|]
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general transcription factor II-I repeat domain-containing protein 1 isoform X31 [Mus musculus]

Protein Classification

GTF2I repeat domain-containing protein( domain architecture ID 10502974)

GTF2I repeat domain-containing protein may be a transcription regulator involved in cell-cycle progression and skeletal muscle differentiation

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
GTF2I pfam02946
GTF2I-like repeat; This region of sequence similarity is found up to six times in a variety of ...
93-167 1.25e-36

GTF2I-like repeat; This region of sequence similarity is found up to six times in a variety of proteins including GTF2I. It has been suggested that this may be a DNA binding domain.


:

Pssm-ID: 427072  Cd Length: 75  Bit Score: 131.59  E-value: 1.25e-36
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1907165361  93 LRKQVEMLFNTKYAKAIGTSEPVKVPYSKFLMHPEELFVLGLPEGISLRRPNCFGIAKLRKILEASNSIQFVIKR 167
Cdd:pfam02946   1 LRKQVEDLFNVKYGEALGLSEPVPVPYEKFQRDPEDLYVEGLPEGVPFRRPSNYDIATLEKILEAKSRISFVIKR 75
GTF2I pfam02946
GTF2I-like repeat; This region of sequence similarity is found up to six times in a variety of ...
375-447 7.13e-32

GTF2I-like repeat; This region of sequence similarity is found up to six times in a variety of proteins including GTF2I. It has been suggested that this may be a DNA binding domain.


:

Pssm-ID: 427072  Cd Length: 75  Bit Score: 118.11  E-value: 7.13e-32
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1907165361 375 LREQVKELFNEKYGEALGLNRPVLVPYKLIRDSPDAVEVKGLPDDIPFRNPNTYDIHRLEKILKAREHVRMVI 447
Cdd:pfam02946   1 LRKQVEDLFNVKYGEALGLSEPVPVPYEKFQRDPEDLYVEGLPEGVPFRRPSNYDIATLEKILEAKSRISFVI 73
GTF2I pfam02946
GTF2I-like repeat; This region of sequence similarity is found up to six times in a variety of ...
478-550 7.13e-32

GTF2I-like repeat; This region of sequence similarity is found up to six times in a variety of proteins including GTF2I. It has been suggested that this may be a DNA binding domain.


:

Pssm-ID: 427072  Cd Length: 75  Bit Score: 118.11  E-value: 7.13e-32
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1907165361 478 LREQVKELFNEKYGEALGLNRPVLVPYKLIRDSPDAVEVKGLPDDIPFRNPNTYDIHRLEKILKAREHVRMVI 550
Cdd:pfam02946   1 LRKQVEDLFNVKYGEALGLSEPVPVPYEKFQRDPEDLYVEGLPEGVPFRRPSNYDIATLEKILEAKSRISFVI 73
GTF2I pfam02946
GTF2I-like repeat; This region of sequence similarity is found up to six times in a variety of ...
251-325 4.97e-28

GTF2I-like repeat; This region of sequence similarity is found up to six times in a variety of proteins including GTF2I. It has been suggested that this may be a DNA binding domain.


:

Pssm-ID: 427072  Cd Length: 75  Bit Score: 107.32  E-value: 4.97e-28
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1907165361 251 LREQVQDLFNKKYGEALGIKYPVQVPYKRIKSNPGSVIIEGLPPGIPFRKPCTFGSQNLERILSVADKIKFTVTR 325
Cdd:pfam02946   1 LRKQVEDLFNVKYGEALGLSEPVPVPYEKFQRDPEDLYVEGLPEGVPFRRPSNYDIATLEKILEAKSRISFVIKR 75
 
Name Accession Description Interval E-value
GTF2I pfam02946
GTF2I-like repeat; This region of sequence similarity is found up to six times in a variety of ...
93-167 1.25e-36

GTF2I-like repeat; This region of sequence similarity is found up to six times in a variety of proteins including GTF2I. It has been suggested that this may be a DNA binding domain.


Pssm-ID: 427072  Cd Length: 75  Bit Score: 131.59  E-value: 1.25e-36
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1907165361  93 LRKQVEMLFNTKYAKAIGTSEPVKVPYSKFLMHPEELFVLGLPEGISLRRPNCFGIAKLRKILEASNSIQFVIKR 167
Cdd:pfam02946   1 LRKQVEDLFNVKYGEALGLSEPVPVPYEKFQRDPEDLYVEGLPEGVPFRRPSNYDIATLEKILEAKSRISFVIKR 75
GTF2I pfam02946
GTF2I-like repeat; This region of sequence similarity is found up to six times in a variety of ...
375-447 7.13e-32

GTF2I-like repeat; This region of sequence similarity is found up to six times in a variety of proteins including GTF2I. It has been suggested that this may be a DNA binding domain.


Pssm-ID: 427072  Cd Length: 75  Bit Score: 118.11  E-value: 7.13e-32
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1907165361 375 LREQVKELFNEKYGEALGLNRPVLVPYKLIRDSPDAVEVKGLPDDIPFRNPNTYDIHRLEKILKAREHVRMVI 447
Cdd:pfam02946   1 LRKQVEDLFNVKYGEALGLSEPVPVPYEKFQRDPEDLYVEGLPEGVPFRRPSNYDIATLEKILEAKSRISFVI 73
GTF2I pfam02946
GTF2I-like repeat; This region of sequence similarity is found up to six times in a variety of ...
478-550 7.13e-32

GTF2I-like repeat; This region of sequence similarity is found up to six times in a variety of proteins including GTF2I. It has been suggested that this may be a DNA binding domain.


Pssm-ID: 427072  Cd Length: 75  Bit Score: 118.11  E-value: 7.13e-32
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1907165361 478 LREQVKELFNEKYGEALGLNRPVLVPYKLIRDSPDAVEVKGLPDDIPFRNPNTYDIHRLEKILKAREHVRMVI 550
Cdd:pfam02946   1 LRKQVEDLFNVKYGEALGLSEPVPVPYEKFQRDPEDLYVEGLPEGVPFRRPSNYDIATLEKILEAKSRISFVI 73
GTF2I pfam02946
GTF2I-like repeat; This region of sequence similarity is found up to six times in a variety of ...
251-325 4.97e-28

GTF2I-like repeat; This region of sequence similarity is found up to six times in a variety of proteins including GTF2I. It has been suggested that this may be a DNA binding domain.


Pssm-ID: 427072  Cd Length: 75  Bit Score: 107.32  E-value: 4.97e-28
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1907165361 251 LREQVQDLFNKKYGEALGIKYPVQVPYKRIKSNPGSVIIEGLPPGIPFRKPCTFGSQNLERILSVADKIKFTVTR 325
Cdd:pfam02946   1 LRKQVEDLFNVKYGEALGLSEPVPVPYEKFQRDPEDLYVEGLPEGVPFRRPSNYDIATLEKILEAKSRISFVIKR 75
 
Name Accession Description Interval E-value
GTF2I pfam02946
GTF2I-like repeat; This region of sequence similarity is found up to six times in a variety of ...
93-167 1.25e-36

GTF2I-like repeat; This region of sequence similarity is found up to six times in a variety of proteins including GTF2I. It has been suggested that this may be a DNA binding domain.


Pssm-ID: 427072  Cd Length: 75  Bit Score: 131.59  E-value: 1.25e-36
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1907165361  93 LRKQVEMLFNTKYAKAIGTSEPVKVPYSKFLMHPEELFVLGLPEGISLRRPNCFGIAKLRKILEASNSIQFVIKR 167
Cdd:pfam02946   1 LRKQVEDLFNVKYGEALGLSEPVPVPYEKFQRDPEDLYVEGLPEGVPFRRPSNYDIATLEKILEAKSRISFVIKR 75
GTF2I pfam02946
GTF2I-like repeat; This region of sequence similarity is found up to six times in a variety of ...
375-447 7.13e-32

GTF2I-like repeat; This region of sequence similarity is found up to six times in a variety of proteins including GTF2I. It has been suggested that this may be a DNA binding domain.


Pssm-ID: 427072  Cd Length: 75  Bit Score: 118.11  E-value: 7.13e-32
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1907165361 375 LREQVKELFNEKYGEALGLNRPVLVPYKLIRDSPDAVEVKGLPDDIPFRNPNTYDIHRLEKILKAREHVRMVI 447
Cdd:pfam02946   1 LRKQVEDLFNVKYGEALGLSEPVPVPYEKFQRDPEDLYVEGLPEGVPFRRPSNYDIATLEKILEAKSRISFVI 73
GTF2I pfam02946
GTF2I-like repeat; This region of sequence similarity is found up to six times in a variety of ...
478-550 7.13e-32

GTF2I-like repeat; This region of sequence similarity is found up to six times in a variety of proteins including GTF2I. It has been suggested that this may be a DNA binding domain.


Pssm-ID: 427072  Cd Length: 75  Bit Score: 118.11  E-value: 7.13e-32
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1907165361 478 LREQVKELFNEKYGEALGLNRPVLVPYKLIRDSPDAVEVKGLPDDIPFRNPNTYDIHRLEKILKAREHVRMVI 550
Cdd:pfam02946   1 LRKQVEDLFNVKYGEALGLSEPVPVPYEKFQRDPEDLYVEGLPEGVPFRRPSNYDIATLEKILEAKSRISFVI 73
GTF2I pfam02946
GTF2I-like repeat; This region of sequence similarity is found up to six times in a variety of ...
251-325 4.97e-28

GTF2I-like repeat; This region of sequence similarity is found up to six times in a variety of proteins including GTF2I. It has been suggested that this may be a DNA binding domain.


Pssm-ID: 427072  Cd Length: 75  Bit Score: 107.32  E-value: 4.97e-28
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1907165361 251 LREQVQDLFNKKYGEALGIKYPVQVPYKRIKSNPGSVIIEGLPPGIPFRKPCTFGSQNLERILSVADKIKFTVTR 325
Cdd:pfam02946   1 LRKQVEDLFNVKYGEALGLSEPVPVPYEKFQRDPEDLYVEGLPEGVPFRRPSNYDIATLEKILEAKSRISFVIKR 75
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.20
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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