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Conserved domains on  [gi|1953417146|ref|XP_038533929|]
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G-protein-signaling modulator 1 isoform X1 [Canis lupus familiaris]

Protein Classification

TPR and TPR_12 domain-containing protein( domain architecture ID 11421204)

protein containing domains TPR, TPR_12, and GoLoco

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
68-321 4.07e-16

Tetratricopeptide (TPR) repeat [General function prediction only];


:

Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 78.12  E-value: 4.07e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953417146  68 YSQLGNAYFYLKEYGRALEYHRHDLLLARtigdrmGEAKASGNLGNTLKVLGRFDEAVVCCQRHLDIAQEQgdkvgeARA 147
Cdd:COG0457    11 YNNLGLAYRRLGRYEEAIEDYEKALELDP------DDAEALYNLGLAYLRLGRYEEALADYEQALELDPDD------AEA 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953417146 148 LYNIGNVYHAKGKqlswnaaqdpghlppdvrepLRRASEFYERNLSLvkelgdRAAQGRAYGNLGNTHYLLGSFMEATAF 227
Cdd:COG0457    79 LNNLGLALQALGR--------------------YEEALEDYDKALEL------DPDDAEALYNLGLALLELGRYDEAIEA 132

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953417146 228 HKERLAIAKEFGDkaaerrAYSNLGNAHIFLGRFDVAAEYYKKTLQLSRQLKDQAVEAQACYSLGNTYTLLQDYERAAEY 307
Cdd:COG0457   133 YERALELDPDDAD------ALYNLGIALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQA 206

                         250
                  ....*....|....
gi 1953417146 308 HLRHLLIAQELADR 321
Cdd:COG0457   207 LRKKLAILTLAALA 220
GoLoco pfam02188
GoLoco motif;
492-513 4.28e-08

GoLoco motif;


:

Pssm-ID: 460481  Cd Length: 22  Bit Score: 48.96  E-value: 4.28e-08
                          10        20
                  ....*....|....*....|..
gi 1953417146 492 ECFFDLLSKFQSSRMDDQRCPL 513
Cdd:pfam02188   1 EDFFDLLARVQSSRLDDQRCSL 22
TPR_12 pfam13424
Tetratricopeptide repeat;
289-357 7.82e-05

Tetratricopeptide repeat;


:

Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 41.22  E-value: 7.82e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1953417146 289 YSLGNTYTLLQDYERAAEYHLRHLLIAQEL--ADRVGEGRACWSLGNAYVSMGSPAQALTFAKKHLEISQE 357
Cdd:pfam13424   7 NNLAAVLRRLGRYDEALELLEKALEIARRLlgPDHPLTATTLLNLGRLYLELGRYEEALELLERALALAEK 77
 
Name Accession Description Interval E-value
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
68-321 4.07e-16

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 78.12  E-value: 4.07e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953417146  68 YSQLGNAYFYLKEYGRALEYHRHDLLLARtigdrmGEAKASGNLGNTLKVLGRFDEAVVCCQRHLDIAQEQgdkvgeARA 147
Cdd:COG0457    11 YNNLGLAYRRLGRYEEAIEDYEKALELDP------DDAEALYNLGLAYLRLGRYEEALADYEQALELDPDD------AEA 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953417146 148 LYNIGNVYHAKGKqlswnaaqdpghlppdvrepLRRASEFYERNLSLvkelgdRAAQGRAYGNLGNTHYLLGSFMEATAF 227
Cdd:COG0457    79 LNNLGLALQALGR--------------------YEEALEDYDKALEL------DPDDAEALYNLGLALLELGRYDEAIEA 132

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953417146 228 HKERLAIAKEFGDkaaerrAYSNLGNAHIFLGRFDVAAEYYKKTLQLSRQLKDQAVEAQACYSLGNTYTLLQDYERAAEY 307
Cdd:COG0457   133 YERALELDPDDAD------ALYNLGIALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQA 206

                         250
                  ....*....|....
gi 1953417146 308 HLRHLLIAQELADR 321
Cdd:COG0457   207 LRKKLAILTLAALA 220
TPR_12 pfam13424
Tetratricopeptide repeat;
206-277 7.88e-09

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 52.77  E-value: 7.88e-09
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1953417146 206 RAYGNLGNTHYLLGSFMEATAFHKERLAIAKEF--GDKAAERRAYSNLGNAHIFLGRFDVAAEYYKKTLQLSRQ 277
Cdd:pfam13424   4 TALNNLAAVLRRLGRYDEALELLEKALEIARRLlgPDHPLTATTLLNLGRLYLELGRYEEALELLERALALAEK 77
GoLoco pfam02188
GoLoco motif;
492-513 4.28e-08

GoLoco motif;


Pssm-ID: 460481  Cd Length: 22  Bit Score: 48.96  E-value: 4.28e-08
                          10        20
                  ....*....|....*....|..
gi 1953417146 492 ECFFDLLSKFQSSRMDDQRCPL 513
Cdd:pfam02188   1 EDFFDLLARVQSSRLDDQRCSL 22
GoLoco smart00390
LGN motif, putative GEFs specific for G-alpha GTPases; GEF specific for Galpha_i proteins
 491-513 4.58e-06

LGN motif, putative GEFs specific for G-alpha GTPases; GEF specific for Galpha_i proteins


Pssm-ID: 214645  Cd Length: 23  Bit Score: 43.26  E-value: 4.58e-06
                           10        20
                   ....*....|....*....|...
gi 1953417146  491 EECFFDLLSKFQSSRMDDQRCPL 513
Cdd:smart00390   1 DEDLFDLLLRMQSSRMDDQRCEL 23
TPR_12 pfam13424
Tetratricopeptide repeat;
289-357 7.82e-05

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 41.22  E-value: 7.82e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1953417146 289 YSLGNTYTLLQDYERAAEYHLRHLLIAQEL--ADRVGEGRACWSLGNAYVSMGSPAQALTFAKKHLEISQE 357
Cdd:pfam13424   7 NNLAAVLRRLGRYDEALELLEKALEIARRLlgPDHPLTATTLLNLGRLYLELGRYEEALELLERALALAEK 77
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 105-137 1.18e-03

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 36.66  E-value: 1.18e-03
                           10        20        30
                   ....*....|....*....|....*....|...
gi 1953417146  105 AKASGNLGNTLKVLGRFDEAVVCCQRHLDIAQE 137
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPN 33
FxSxx_TPR NF040586
FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about ...
 206-381 4.30e-03

FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about 850 amino acids long, or 1300 long because of an additional N-terminal domain. Proteins have a P-loop motif, GxGGxGKT, near the N-terminus of the region covered by this HMM, and a region over 400 residues long of tetratricopeptide repeat sequence. The family is found regularly next to other components of FxSxx-COOH systems, which feature an FxsB family radical SAM protein and a protein modified by it, FxsA. Members of this FxsA family typically have an FxSxx motif as the final five amino acids.


Pssm-ID: 468560 [Multi-domain]  Cd Length: 836  Bit Score: 40.29  E-value: 4.30e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953417146 206 RAYGNLGNTHYLLGSFMEATAFHKERLAIAKE-FGDKAAE-RRAYSNLGNAHIFLGRFDVAAEYYKKTLQLSRQL---KD 280
Cdd:NF040586  479 MTAGGLGADLRALGRFREALELDEETLERHRRvFGEDHPRtLRAANNLAVSLRLLGDYREALELDREVLRRRRRVlgpDH 558

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953417146 281 QAVEAQACySLGNTYTLLQDYERAAEY---HLRHLLIAQELADRVGEGRACWSLGNAYVSMGSPAQALTFAKkhlEISQE 357
Cdd:NF040586  559 PRTLLSAN-NLARDLRELGRYAEALDLleeALERYREVLGGPDHPDTLRAAKSLAVALRRAGRLEEALELAE---DTYER 634

                         170       180
                  ....*....|....*....|....*....
gi 1953417146 358 IGDRNGE-----LTARMNVAQLQLVLGRL 381
Cdd:NF040586  635 YRRRFGPdhpdtLAAALSLANDLRALGDA 663
 
Name Accession Description Interval E-value
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
68-321 4.07e-16

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 78.12  E-value: 4.07e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953417146  68 YSQLGNAYFYLKEYGRALEYHRHDLLLARtigdrmGEAKASGNLGNTLKVLGRFDEAVVCCQRHLDIAQEQgdkvgeARA 147
Cdd:COG0457    11 YNNLGLAYRRLGRYEEAIEDYEKALELDP------DDAEALYNLGLAYLRLGRYEEALADYEQALELDPDD------AEA 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953417146 148 LYNIGNVYHAKGKqlswnaaqdpghlppdvrepLRRASEFYERNLSLvkelgdRAAQGRAYGNLGNTHYLLGSFMEATAF 227
Cdd:COG0457    79 LNNLGLALQALGR--------------------YEEALEDYDKALEL------DPDDAEALYNLGLALLELGRYDEAIEA 132

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953417146 228 HKERLAIAKEFGDkaaerrAYSNLGNAHIFLGRFDVAAEYYKKTLQLSRQLKDQAVEAQACYSLGNTYTLLQDYERAAEY 307
Cdd:COG0457   133 YERALELDPDDAD------ALYNLGIALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQA 206

                         250
                  ....*....|....
gi 1953417146 308 HLRHLLIAQELADR 321
Cdd:COG0457   207 LRKKLAILTLAALA 220
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
104-376 6.35e-16

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 77.74  E-value: 6.35e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953417146 104 EAKASGNLGNTLKVLGRFDEAVVCCQRHLDIAQEqgdkvgEARALYNIGNVYHAKGKqlswnaaqdpghlppdvrepLRR 183
Cdd:COG0457     7 DAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPD------DAEALYNLGLAYLRLGR--------------------YEE 60

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953417146 184 ASEFYERNLSLvkelgdRAAQGRAYGNLGNTHYLLGSFMEATAFHKERLAIAKEFGDkaaerrAYSNLGNAHIFLGRFDV 263
Cdd:COG0457    61 ALADYEQALEL------DPDDAEALNNLGLALQALGRYEEALEDYDKALELDPDDAE------ALYNLGLALLELGRYDE 128

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953417146 264 AAEYYKKTLQLSRQLkdqaveAQACYSLGNTYTLLQDYERAAEYHLRHLLIAQELADRVGEGRACWSLGNAYvsmgspAQ 343
Cdd:COG0457   129 AIEAYERALELDPDD------ADALYNLGIALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAE------VL 196

                         250       260       270
                  ....*....|....*....|....*....|...
gi 1953417146 344 ALTFAKKHLEISQEIGDRNGELTARMNVAQLQL 376
Cdd:COG0457   197 LALLLALEQALRKKLAILTLAALAELLLLALAL 229
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
144-423 7.72e-15

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 74.66  E-value: 7.72e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953417146 144 EARALYNIGNVYHAKGKqlswnaaqdpghlppdvrepLRRASEFYERNLSLVKELGDraaqgrAYGNLGNTHYLLGSFME 223
Cdd:COG0457     7 DAEAYNNLGLAYRRLGR--------------------YEEAIEDYEKALELDPDDAE------ALYNLGLAYLRLGRYEE 60

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953417146 224 ATAFHKERLAIAKEFGDkaaerrAYSNLGNAHIFLGRFDVAAEYYKKTLQLSRQLkdqaveAQACYSLGNTYTLLQDYER 303
Cdd:COG0457    61 ALADYEQALELDPDDAE------ALNNLGLALQALGRYEEALEDYDKALELDPDD------AEALYNLGLALLELGRYDE 128

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953417146 304 AAEYHLRHLLIAQELADrvgegrACWSLGNAYVSMGSPAQALTFAKKHLEisQEIGDRNGELTARMNVAQLQLVLGRLTS 383
Cdd:COG0457   129 AIEAYERALELDPDDAD------ALYNLGIALEKLGRYEEALELLEKLEA--AALAALLAAALGEAALALAAAEVLLALL 200

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|
gi 1953417146 384 PAATEKPDLAGYEAQGARPKRTQRLSAETWGLLRLPLERE 423
Cdd:COG0457   201 LALEQALRKKLAILTLAALAELLLLALALLLALRLAALAL 240
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 32-353 5.70e-14

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 72.45  E-value: 5.70e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953417146  32 LEGERLCKAGDFKAGAAFFEAAVQVGTEDLKTlsaiYSQLGNAYFYLKEYGRALEYHRHdlLLARTiGDRmgeAKASGNL 111
Cdd:COG2956    13 FKGLNYLLNGQPDKAIDLLEEALELDPETVEA----HLALGNLYRRRGEYDRAIRIHQK--LLERD-PDR---AEALLEL 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953417146 112 GNTLKVLGRFDEAVVCCQRHLDIAQEQgdkvgeARALYNIGNVYHAKGKqlswnaaqdpghlppdvrepLRRASEFYERn 191
Cdd:COG2956    83 AQDYLKAGLLDRAEELLEKLLELDPDD------AEALRLLAEIYEQEGD--------------------WEKAIEVLER- 135

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953417146 192 lsLVKELGDRAaqgRAYGNLGNTHYLLGSFMEATAFHKERLAIAKEFgdkaaeRRAYSNLGNAHIFLGRFDVAAEYYKKT 271
Cdd:COG2956   136 --LLKLGPENA---HAYCELAELYLEQGDYDEAIEALEKALKLDPDC------ARALLLLAELYLEQGDYEEAIAALERA 204

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953417146 272 LQLSRQLkdqaveAQACYSLGNTYTLLQDYERAAEYHLRHLLIAQELADRVgegracwSLGNAYVSMGSPAQALTFAKKH 351
Cdd:COG2956   205 LEQDPDY------LPALPRLAELYEKLGDPEEALELLRKALELDPSDDLLL-------ALADLLERKEGLEAALALLERQ 271


                  ..
gi 1953417146 352 LE 353
Cdd:COG2956   272 LR 273
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 30-274 9.65e-12

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 68.10  E-value: 9.65e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953417146  30 LALEGERLCKAGDFKAGAAFFEAAVQvGTEDLKTLSAIYSQLGNAYFYLKEYGRALEYHRHDLLLARTIGDRMGEAKASG 109
Cdd:COG3914     4 AALLALAALAAAALLAAAAAAELALA-AELEAAALAAALGLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLE 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953417146 110 NLGNTLKVLGRFDEAVVCCQRHLDIAqeqgdkVGEARALYNIGNVYHAKGKqlswnaaqdpghlppdvrepLRRASEFYE 189
Cdd:COG3914    83 LAALLLQALGRYEEALALYRRALALN------PDNAEALFNLGNLLLALGR--------------------LEEALAALR 136

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953417146 190 RNLSLvkelgdRAAQGRAYGNLGNTHYLLGSFMEATAFHKERLAIAKEFGDkaaerrAYSNLGNAHIFLGRFDVAAEYYK 269
Cdd:COG3914   137 RALAL------NPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAE------ALNNLGNALQDLGRLEEAIAAYR 204


                  ....*
gi 1953417146 270 KTLQL 274
Cdd:COG3914   205 RALEL 209
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 110-358 2.30e-09

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 58.59  E-value: 2.30e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953417146 110 NLGNTLKVLGRFDEAVVCCQRHLDIAQEQgdkvgeARALYNIGNVYHAKGKqlswnaaqdpghlppdvrepLRRASEFYE 189
Cdd:COG2956    47 ALGNLYRRRGEYDRAIRIHQKLLERDPDR------AEALLELAQDYLKAGL--------------------LDRAEELLE 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953417146 190 RnlsLVKELGDRAaqgRAYGNLGNTHYLLGSFMEATAFHKERLAIAKEfgdkaaERRAYSNLGNAHIFLGRFDVAAEYYK 269
Cdd:COG2956   101 K---LLELDPDDA---EALRLLAEIYEQEGDWEKAIEVLERLLKLGPE------NAHAYCELAELYLEQGDYDEAIEALE 168

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953417146 270 KTLQLSRQlkdqAVEAQacYSLGNTYTLLQDYERAAEyHLRHLLIAQELADRVGEgracwSLGNAYVSMGSPAQALTFAK 349
Cdd:COG2956   169 KALKLDPD----CARAL--LLLAELYLEQGDYEEAIA-ALERALEQDPDYLPALP-----RLAELYEKLGDPEEALELLR 236


                  ....*....
gi 1953417146 350 KHLEISQEI 358
Cdd:COG2956   237 KALELDPSD 245
TPR_12 pfam13424
Tetratricopeptide repeat;
206-277 7.88e-09

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 52.77  E-value: 7.88e-09
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1953417146 206 RAYGNLGNTHYLLGSFMEATAFHKERLAIAKEF--GDKAAERRAYSNLGNAHIFLGRFDVAAEYYKKTLQLSRQ 277
Cdd:pfam13424   4 TALNNLAAVLRRLGRYDEALELLEKALEIARRLlgPDHPLTATTLLNLGRLYLELGRYEEALELLERALALAEK 77
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 2-277 9.00e-09

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 58.47  E-value: 9.00e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953417146   2 AGPAPSAADELPGPARRLYSRMEASCLELALEGERLCKAGDFKAGAAFFEAAvqvgtEDLKTLSAIYSQLGNAYFYLKEY 81
Cdd:COG3914    20 AAAAAELALAAELEAAALAAALGLALLLLAALAEAAAAALLALAAGEAAAAA-----AALLLLAALLELAALLLQALGRY 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953417146  82 GRALEYHRHDLLLARTigdrmgEAKASGNLGNTLKVLGRFDEAVVCCQRHLDIAQEQgdkvgeARALYNIGNVYHAKGKq 161
Cdd:COG3914    95 EEALALYRRALALNPD------NAEALFNLGNLLLALGRLEEALAALRRALALNPDF------AEAYLNLGEALRRLGR- 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953417146 162 lswnaaqdpghlppdvrepLRRASEFYERNLSLvkelgdRAAQGRAYGNLGNTHYLLGSFMEATAFHKERLAIAKEFgdk 241
Cdd:COG3914   162 -------------------LEEAIAALRRALEL------DPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDN--- 213

                         250       260       270
                  ....*....|....*....|....*....|....*.
gi 1953417146 242 aaeRRAYSNLGNAHIFLGRFDVAAEYYKKTLQLSRQ 277
Cdd:COG3914   214 ---ADAHSNLLFALRQACDWEVYDRFEELLAALARG 246
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 182-381 2.74e-08

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 56.93  E-value: 2.74e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953417146 182 RRASEFYERNLSLVKELGDRAAQGRAYGNLGNTHYLLGSFMEATAFHKERLAIAKEFGDKAAERRAYSNLGNAHIFLGRF 261
Cdd:COG3914    15 AALLAAAAAAELALAAELEAAALAAALGLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLELAALLLQALGRY 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953417146 262 DVAAEYYKKTLQLSRQlkdqavEAQACYSLGNTYTLLQDYERAAEYHLRHLLIAQELADrvgegrACWSLGNAYVSMGSP 341
Cdd:COG3914    95 EEALALYRRALALNPD------NAEALFNLGNLLLALGRLEEALAALRRALALNPDFAE------AYLNLGEALRRLGRL 162

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 1953417146 342 AQALTFAKKHLEIsqeigdRNGELTARMNVAQLQLVLGRL 381
Cdd:COG3914   163 EEAIAALRRALEL------DPDNAEALNNLGNALQDLGRL 196
GoLoco pfam02188
GoLoco motif;
492-513 4.28e-08

GoLoco motif;


Pssm-ID: 460481  Cd Length: 22  Bit Score: 48.96  E-value: 4.28e-08
                          10        20
                  ....*....|....*....|..
gi 1953417146 492 ECFFDLLSKFQSSRMDDQRCPL 513
Cdd:pfam02188   1 EDFFDLLARVQSSRLDDQRCSL 22
COG3899 COG3899
Predicted ATPase [General function prediction only];
121-423 2.14e-07

Predicted ATPase [General function prediction only];


Pssm-ID: 443106 [Multi-domain]  Cd Length: 1244  Bit Score: 54.09  E-value: 2.14e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953417146  121 FDEAVVCCQRHLDIAQEQGDKVGEARALYNIGNVYHAKGKqlswnaaqdpghlPPDVREPLRRASEFYERNLSLVKELGD 200
Cdd:COG3899    721 YAEALRYLERALELLPPDPEEEYRLALLLELAEALYLAGR-------------FEEAEALLERALAARALAALAALRHGN 787

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953417146  201 RAAQGRAYGNLGntHYLLGSFMEATAFHKERLAIAKEFGDKAAERRAYSNLGNAHIFLGRFDVAAEYYKKTLQLSRQLKD 280
Cdd:COG3899    788 PPASARAYANLG--LLLLGDYEEAYEFGELALALAERLGDRRLEARALFNLGFILHWLGPLREALELLREALEAGLETGD 865

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953417146  281 QAVEAQACYSLGNTyTLLQDYERAAEYHLRHLLIAQELADRVGEGRACWSLGNAYVSMGSPAQALTFAKKHLEISQEIGD 360
Cdd:COG3899    866 AALALLALAAAAAA-AAAAAALAAAAAAAARLLAAAAAALAAAAAAAALAAAELARLAAAAAAAAALALAAAAAAAAAAA 944

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1953417146  361 RNGELTARMNVAQLQLVLGRLTSPAATEKPDLAGYEAQGARPKRTQRLSAETWGLLRLPLERE 423
Cdd:COG3899    945 LAAAAAAAALAAALALAAAAAAAAAAALAAAAAAAAAAAAAAAAAALEAAAAALLALLAAAAA 1007
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
34-248 1.06e-06

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 50.39  E-value: 1.06e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953417146  34 GERLCKAGDFKAGAAFFEAAVQVGTEDlktlSAIYSQLGNAYFYLKEYGRALEYHRHDLLLartigdRMGEAKASGNLGN 113
Cdd:COG0457    49 GLAYLRLGRYEEALADYEQALELDPDD----AEALNNLGLALQALGRYEEALEDYDKALEL------DPDDAEALYNLGL 118

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953417146 114 TLKVLGRFDEAVVCCQRHLDIaqeqgdKVGEARALYNIGNVYHAKGKqlsWNAAQDPGHLPPDVREPLRRASEFYERNLS 193
Cdd:COG0457   119 ALLELGRYDEAIEAYERALEL------DPDDADALYNLGIALEKLGR---YEEALELLEKLEAAALAALLAAALGEAALA 189

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1953417146 194 LVKELGDRAAQGRAYGNLGNTHYLLGSFMEATAFHKERLAIAKEFGDKAAERRAY 248
Cdd:COG0457   190 LAAAEVLLALLLALEQALRKKLAILTLAALAELLLLALALLLALRLAALALYQYR 244
TPR_12 pfam13424
Tetratricopeptide repeat;
246-317 1.70e-06

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 45.84  E-value: 1.70e-06
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1953417146 246 RAYSNLGNAHIFLGRFDVAAEYYKKTLQLSRQL--KDQAVEAQACYSLGNTYTLLQDYERAAEYHLRHLLIAQE 317
Cdd:pfam13424   4 TALNNLAAVLRRLGRYDEALELLEKALEIARRLlgPDHPLTATTLLNLGRLYLELGRYEEALELLERALALAEK 77
GoLoco smart00390
LGN motif, putative GEFs specific for G-alpha GTPases; GEF specific for Galpha_i proteins
 491-513 4.58e-06

LGN motif, putative GEFs specific for G-alpha GTPases; GEF specific for Galpha_i proteins


Pssm-ID: 214645  Cd Length: 23  Bit Score: 43.26  E-value: 4.58e-06
                           10        20
                   ....*....|....*....|...
gi 1953417146  491 EECFFDLLSKFQSSRMDDQRCPL 513
Cdd:smart00390   1 DEDLFDLLLRMQSSRMDDQRCEL 23
TPR_12 pfam13424
Tetratricopeptide repeat;
105-161 1.14e-05

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 43.53  E-value: 1.14e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 1953417146 105 AKASGNLGNTLKVLGRFDEAVVCCQRHLDIAQEQ--GDKVGEARALYNIGNVYHAKGKQ 161
Cdd:pfam13424   3 ATALNNLAAVLRRLGRYDEALELLEKALEIARRLlgPDHPLTATTLLNLGRLYLELGRY 61
TPR_12 pfam13424
Tetratricopeptide repeat;
64-137 2.90e-05

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 42.37  E-value: 2.90e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1953417146  64 LSAIYSQLGNAYFYLKEYGRALEYHRHDLLLARTI--GDRMGEAKASGNLGNTLKVLGRFDEAVVCCQRHLDIAQE 137
Cdd:pfam13424   2 VATALNNLAAVLRRLGRYDEALELLEKALEIARRLlgPDHPLTATTLLNLGRLYLELGRYEEALELLERALALAEK 77
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 207-317 3.94e-05

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 43.64  E-value: 3.94e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953417146 207 AYGNLGNTHYLLGSFMEATAFHKERLAIAKEfgdkaaERRAYSNLGNAHIFLGRFDVAAEYYKKTLQLSRQlkdqavEAQ 286
Cdd:COG4783    40 AFALLGEILLQLGDLDEAIVLLHEALELDPD------EPEARLNLGLALLKAGDYDEALALLEKALKLDPE------HPE 107

                          90       100       110
                  ....*....|....*....|....*....|.
gi 1953417146 287 ACYSLGNTYTLLQDYERAAEYHLRHLLIAQE 317
Cdd:COG4783   108 AYLRLARAYRALGRPDEAIAALEKALELDPD 138
TPR_12 pfam13424
Tetratricopeptide repeat;
289-357 7.82e-05

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 41.22  E-value: 7.82e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1953417146 289 YSLGNTYTLLQDYERAAEYHLRHLLIAQEL--ADRVGEGRACWSLGNAYVSMGSPAQALTFAKKHLEISQE 357
Cdd:pfam13424   7 NNLAAVLRRLGRYDEALELLEKALEIARRLlgPDHPLTATTLLNLGRLYLELGRYEEALELLERALALAEK 77
COG3899 COG3899
Predicted ATPase [General function prediction only];
28-463 1.47e-04

Predicted ATPase [General function prediction only];


Pssm-ID: 443106 [Multi-domain]  Cd Length: 1244  Bit Score: 45.23  E-value: 1.47e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953417146   28 LELALE-GERLCKAGDFKAGAAFFEAAVQVGT-------EDLKTLSAIYSQLGNAYFYLKEYGRALEYHRHDLLLARTIG 99
Cdd:COG3899    745 LALLLElAEALYLAGRFEEAEALLERALAARAlaalaalRHGNPPASARAYANLGLLLLGDYEEAYEFGELALALAERLG 824

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953417146  100 DRMGEAKASGNLGNTLKVLGRFDEAVVCCQRHLDIAQEQGDKVGEARALYnignvyhakgkQLSWNAAQDPGHLPPDVRE 179
Cdd:COG3899    825 DRRLEARALFNLGFILHWLGPLREALELLREALEAGLETGDAALALLALA-----------AAAAAAAAAAALAAAAAAA 893

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953417146  180 PLRRASEFYERNLSLVKELGDRAAQGRAYGNLGNTHYLLGSFMEATAFHKERLAIAKEFGDKAAERRAYSNLGNAHIFLG 259
Cdd:COG3899    894 ARLLAAAAAALAAAAAAAALAAAELARLAAAAAAAAALALAAAAAAAAAAALAAAAAAAALAAALALAAAAAAAAAAALA 973

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953417146  260 RFDVAAEYY---KKTLQLSRQLKDQAVEAQACYSLGNTYTLLQDYERAAEYHLRHLLIAQELADRVGEGRACWSLGNAYV 336
Cdd:COG3899    974 AAAAAAAAAaaaAAAAALEAAAAALLALLAAAAAAAAAAAALAAALLAAALAALAAAAAAAALLAAAAALALLAALAAAA 1053

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953417146  337 SMGSPAQALTFAKKHLEISQEIGDRNGELTARMNVAQLQLVLGRLTSPAATEKPDLAGYEAQGARPKRTQRLSAETWGLL 416
Cdd:COG3899   1054 AAAAAAAALAAAAALLAAAAAAAAAAAAAAAAAALAAALAAAALAAAAAAALALAAALAALALAAALAALALAAAARAAA 1133

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|....*..
gi 1953417146  417 RLPLEREQNGDSHQVGEWRGPGRDMLPLPMRSRKYQEGLEATERPRE 463
Cdd:COG3899   1134 ALLLLAAALALALAALLLLAALLLALALLLLALAALALAAALAALAA 1180
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 29-160 1.57e-04

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 42.10  E-value: 1.57e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953417146  29 ELALEGERLCKAGDFKAGAAFFEAAVQVGTEDLktlsAIYSQLGNAYFYLKEYGRALEYHRHDLLLARtigdrmGEAKAS 108
Cdd:COG4783     6 ALYALAQALLLAGDYDEAEALLEKALELDPDNP----EAFALLGEILLQLGDLDEAIVLLHEALELDP------DEPEAR 75

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1953417146 109 GNLGNTLKVLGRFDEAVVCCQRHLDIAQEQgdkvgeARALYNIGNVYHAKGK 160
Cdd:COG4783    76 LNLGLALLKAGDYDEALALLEKALKLDPEH------PEAYLRLARAYRALGR 121
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 178-319 1.58e-04

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 42.64  E-value: 1.58e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953417146 178 REPLRRASEFYERNLSLVKELGDRAAQGRAYGNLGNTHYLLGSFMEATAFHKERLAIAKEFGDkaaerrAYSNLGNAHIF 257
Cdd:COG5010    27 YEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPE------LYYNLALLYSR 100

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1953417146 258 LGRFDVAAEYYKKTLQLSRQlkdqavEAQACYSLGNTYTLLQDYERAAEyHLRHLLIAQELA 319
Cdd:COG5010   101 SGDKDEAKEYYEKALALSPD------NPNAYSNLAALLLSLGQDDEAKA-ALQRALGTSPLK 155
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 242-381 2.15e-04

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 41.72  E-value: 2.15e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953417146 242 AAERRAYSNLGNAHIFLGRFDVAAEYYKKTLQLSRQlkdqavEAQACYSLGNTYTLLQDYERAAEYhlrhllIAQELADR 321
Cdd:COG4783     1 AACAEALYALAQALLLAGDYDEAEALLEKALELDPD------NPEAFALLGEILLQLGDLDEAIVL------LHEALELD 68

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953417146 322 VGEGRACWSLGNAYVSMGSPAQALTFAKKHLEISQEIGDrngeltARMNVAQLQLVLGRL 381
Cdd:COG4783    69 PDEPEARLNLGLALLKAGDYDEALALLEKALKLDPEHPE------AYLRLARAYRALGRP 122
TPR_7 pfam13176
Tetratricopeptide repeat;
287-321 2.53e-04

Tetratricopeptide repeat;


Pssm-ID: 433012 [Multi-domain]  Cd Length: 36  Bit Score: 38.68  E-value: 2.53e-04
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 1953417146 287 ACYSLGNTYTLLQDYERAAEYHLRHLLIAQELADR 321
Cdd:pfam13176   1 ALLNLGRIYRKLGDYDEAISLYEQALALAKDPYDR 35
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 246-355 3.49e-04

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 40.76  E-value: 3.49e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953417146 246 RAYSNLGNAHIFLGRFDVAAEYYKKTLQLSRQlkdqavEAQACYSLGNTYTLLQDYERAAEyhlrhlLIAQELADRVGEG 325
Cdd:COG4235    18 EGWLLLGRAYLRLGRYDEALAAYEKALRLDPD------NADALLDLAEALLAAGDTEEAEE------LLERALALDPDNP 85

                          90       100       110
                  ....*....|....*....|....*....|
gi 1953417146 326 RACWSLGNAYVSMGSPAQALTFAKKHLEIS 355
Cdd:COG4235    86 EALYLLGLAAFQQGDYAEAIAAWQKLLALL 115
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 254-350 4.95e-04

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 39.97  E-value: 4.95e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953417146 254 AHIFLGRFDVAAEYYKktlQLSRQLKDQAVEAQACYSLGNTYTLLQDYERAAEYHLRhllIAQELADRVGEGRACWSLGN 333
Cdd:COG1729     2 ALLKAGDYDEAIAAFK---AFLKRYPNSPLAPDALYWLGEAYYALGDYDEAAEAFEK---LLKRYPDSPKAPDALLKLGL 75

                          90
                  ....*....|....*..
gi 1953417146 334 AYVSMGSPAQALTFAKK 350
Cdd:COG1729    76 SYLELGDYDKARATLEE 92
TPR_1 pfam00515
Tetratricopeptide repeat;
246-274 5.92e-04

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 37.40  E-value: 5.92e-04
                          10        20
                  ....*....|....*....|....*....
gi 1953417146 246 RAYSNLGNAHIFLGRFDVAAEYYKKTLQL 274
Cdd:pfam00515   2 KALYNLGNAYFKLGKYDEALEYYEKALEL 30
TPR_12 pfam13424
Tetratricopeptide repeat;
145-237 1.04e-03

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 38.14  E-value: 1.04e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953417146 145 ARALYNIGNVYHAKGKqlswnaaqdpghlppdvrepLRRASEFYERNLSLVKEL--GDRAAQGRAYGNLGNTHYLLGSFM 222
Cdd:pfam13424   3 ATALNNLAAVLRRLGR--------------------YDEALELLEKALEIARRLlgPDHPLTATTLLNLGRLYLELGRYE 62

                          90
                  ....*....|....*
gi 1953417146 223 EATAFHKERLAIAKE 237
Cdd:pfam13424  63 EALELLERALALAEK 77
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
181-278 1.10e-03

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 38.61  E-value: 1.10e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953417146 181 LRRASEFYERNLSLvkelgdRAAQGRAYGNLGNTHYLLGSFMEATAFHKerlAIAKEFGDKaaerRAYSNLGNAHIFLGR 260
Cdd:COG3063     8 LEEAEEYYEKALEL------DPDNADALNNLGLLLLEQGRYDEAIALEK---ALKLDPNNA----EALLNLAELLLELGD 74

                          90
                  ....*....|....*...
gi 1953417146 261 FDVAAEYYKKTLQLSRQL 278
Cdd:COG3063    75 YDEALAYLERALELDPSA 92
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 105-137 1.18e-03

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 36.66  E-value: 1.18e-03
                           10        20        30
                   ....*....|....*....|....*....|...
gi 1953417146  105 AKASGNLGNTLKVLGRFDEAVVCCQRHLDIAQE 137
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPN 33
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
254-357 1.24e-03

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 38.23  E-value: 1.24e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953417146 254 AHIFLGRFDVAAEYYKKTLQLSRQlkdqavEAQACYSLGNTYTLLQDYERAAEYHlRHLLIAQELADrvgegrACWSLGN 333
Cdd:COG3063     1 LYLKLGDLEEAEEYYEKALELDPD------NADALNNLGLLLLEQGRYDEAIALE-KALKLDPNNAE------ALLNLAE 67

                          90       100
                  ....*....|....*....|....
gi 1953417146 334 AYVSMGSPAQALTFAKKHLEISQE 357
Cdd:COG3063    68 LLLELGDYDEALAYLERALELDPS 91
TPR_1 pfam00515
Tetratricopeptide repeat;
105-137 1.48e-03

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 36.24  E-value: 1.48e-03
                          10        20        30
                  ....*....|....*....|....*....|...
gi 1953417146 105 AKASGNLGNTLKVLGRFDEAVVCCQRHLDIAQE 137
Cdd:pfam00515   1 AKALYNLGNAYFKLGKYDEALEYYEKALELNPN 33
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
165-353 1.93e-03

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 40.28  E-value: 1.93e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953417146 165 NAAQDPGHLPPDVREPLRRASEFYERNLSLVKELGDRAAQGRAYGNLGNTHYLLGSFMEATAF-HKERLAIAKEFGDKAA 243
Cdd:COG4785    21 KAAILLAALLFAAVLALAIALADLALALAAAALAAAALAAERIDRALALPDLAQLYYERGVAYdSLGDYDLAIADFDQAL 100

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953417146 244 ER-----RAYSNLGNAHIFLGRFDVAAEYYKKTLQLSRQlKDQAV--EAQACYSLGNTYTLLQDYERAAEY-------HL 309
Cdd:COG4785   101 ELdpdlaEAYNNRGLAYLLLGDYDAALEDFDRALELDPD-YAYAYlnRGIALYYLGRYELAIADLEKALELdpndperAL 179

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 1953417146 310 RHLLIAQELADRVGEGRACWSLGNAYVSMGSPAQALTFAKKHLE 353
Cdd:COG4785   180 WLYLAERKLDPEKALALLLEDWATAYLLQGDTEEARELFKLALA 223
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 233-307 3.89e-03

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 37.28  E-value: 3.89e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1953417146 233 AIAKEFGDKAAERRAYSNLGNAHIFLGRFDVAAEYYKKTLQLSrqlKDQAVEAQACYSLGNTYTLLQDYERAAEY 307
Cdd:COG1729    18 AFLKRYPNSPLAPDALYWLGEAYYALGDYDEAAEAFEKLLKRY---PDSPKAPDALLKLGLSYLELGDYDKARAT 89
FxSxx_TPR NF040586
FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about ...
 206-381 4.30e-03

FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about 850 amino acids long, or 1300 long because of an additional N-terminal domain. Proteins have a P-loop motif, GxGGxGKT, near the N-terminus of the region covered by this HMM, and a region over 400 residues long of tetratricopeptide repeat sequence. The family is found regularly next to other components of FxSxx-COOH systems, which feature an FxsB family radical SAM protein and a protein modified by it, FxsA. Members of this FxsA family typically have an FxSxx motif as the final five amino acids.


Pssm-ID: 468560 [Multi-domain]  Cd Length: 836  Bit Score: 40.29  E-value: 4.30e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953417146 206 RAYGNLGNTHYLLGSFMEATAFHKERLAIAKE-FGDKAAE-RRAYSNLGNAHIFLGRFDVAAEYYKKTLQLSRQL---KD 280
Cdd:NF040586  479 MTAGGLGADLRALGRFREALELDEETLERHRRvFGEDHPRtLRAANNLAVSLRLLGDYREALELDREVLRRRRRVlgpDH 558

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1953417146 281 QAVEAQACySLGNTYTLLQDYERAAEY---HLRHLLIAQELADRVGEGRACWSLGNAYVSMGSPAQALTFAKkhlEISQE 357
Cdd:NF040586  559 PRTLLSAN-NLARDLRELGRYAEALDLleeALERYREVLGGPDHPDTLRAAKSLAVALRRAGRLEEALELAE---DTYER 634

                         170       180
                  ....*....|....*....|....*....
gi 1953417146 358 IGDRNGE-----LTARMNVAQLQLVLGRL 381
Cdd:NF040586  635 YRRRFGPdhpdtLAAALSLANDLRALGDA 663
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 285-317 4.78e-03

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 35.11  E-value: 4.78e-03
                           10        20        30
                   ....*....|....*....|....*....|...
gi 1953417146  285 AQACYSLGNTYTLLQDYERAAEYHLRHLLIAQE 317
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPN 33
TPR_2 pfam07719
Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats ...
 246-277 8.34e-03

Tetratricopeptide repeat; This Pfam entry includes outlying Tetratricopeptide-like repeats (TPR) that are not matched by pfam00515.


Pssm-ID: 429619 [Multi-domain]  Cd Length: 33  Bit Score: 34.42  E-value: 8.34e-03
                          10        20        30
                  ....*....|....*....|....*....|..
gi 1953417146 246 RAYSNLGNAHIFLGRFDVAAEYYKKTLQLSRQ 277
Cdd:pfam07719   2 EALYNLGLAYYKLGDYEEALEAYEKALELDPN 33
TPR_10 pfam13374
Tetratricopeptide repeat;
246-278 9.97e-03

Tetratricopeptide repeat;


Pssm-ID: 463861 [Multi-domain]  Cd Length: 42  Bit Score: 34.40  E-value: 9.97e-03
                          10        20        30
                  ....*....|....*....|....*....|...
gi 1953417146 246 RAYSNLGNAHIFLGRFDVAAEYYKKTLQLSRQL 278
Cdd:pfam13374   3 SSLNNLANALRAQGRYDEAEELLEEALAIRERV 35
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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