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Conserved domains on  [gi|1958791295|ref|XP_038935792|]
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CCN family member 4 isoform X1 [Rattus norvegicus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TSP1_CCN pfam19035
CCN3 Nov like TSP1 domain; This entry represents a sub-type of TSP1 domains found in ...
 138-181 1.93e-16

CCN3 Nov like TSP1 domain; This entry represents a sub-type of TSP1 domains found in matricellular CCN proteins that have an alternative disulphide binding pattern compared to the canonical TSP1 domains.


:

Pssm-ID: 465952  Cd Length: 44  Bit Score: 71.60  E-value: 1.93e-16
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 1958791295 138 CIAYTSPWSPCSTTCGLGISTRISNVNARCWPEQESRLCNLRPC 181
Cdd:pfam19035   1 CEEQSTEWSPCSKTCGMGVSTRVSNDNAECKLVTETRLCQLRPC 44
VWC smart00214
von Willebrand factor (vWF) type C domain;
45-103 6.98e-07

von Willebrand factor (vWF) type C domain;


:

Pssm-ID: 214564  Cd Length: 59  Bit Score: 45.58  E-value: 6.98e-07
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958791295   45 CVLDGVRYTNGESFQPNCRYNCTCIDG-TVGCTPLclsPRPPRLWCRQPRHVRVPGQCCE 103
Cdd:smart00214   1 CVHNGRVYNDGETWKPDPCQICTCLDGtTVLCDPV---ECPPPPDCPNPERVKPPGECCP 57
 
Name Accession Description Interval E-value
TSP1_CCN pfam19035
CCN3 Nov like TSP1 domain; This entry represents a sub-type of TSP1 domains found in ...
 138-181 1.93e-16

CCN3 Nov like TSP1 domain; This entry represents a sub-type of TSP1 domains found in matricellular CCN proteins that have an alternative disulphide binding pattern compared to the canonical TSP1 domains.


Pssm-ID: 465952  Cd Length: 44  Bit Score: 71.60  E-value: 1.93e-16
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 1958791295 138 CIAYTSPWSPCSTTCGLGISTRISNVNARCWPEQESRLCNLRPC 181
Cdd:pfam19035   1 CEEQSTEWSPCSKTCGMGVSTRVSNDNAECKLVTETRLCQLRPC 44
VWC smart00214
von Willebrand factor (vWF) type C domain;
45-103 6.98e-07

von Willebrand factor (vWF) type C domain;


Pssm-ID: 214564  Cd Length: 59  Bit Score: 45.58  E-value: 6.98e-07
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958791295   45 CVLDGVRYTNGESFQPNCRYNCTCIDG-TVGCTPLclsPRPPRLWCRQPRHVRVPGQCCE 103
Cdd:smart00214   1 CVHNGRVYNDGETWKPDPCQICTCLDGtTVLCDPV---ECPPPPDCPNPERVKPPGECCP 57
VWC pfam00093
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with ...
 45-104 1.46e-06

von Willebrand factor type C domain; The high cutoff was used to prevent overlap with pfam00094.


Pssm-ID: 278520  Cd Length: 57  Bit Score: 44.72  E-value: 1.46e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958791295  45 CVLDGVRYTNGESFQPNCRYNCTCIDGTVGCTPLclspRPPRLWCRQPRHVRVPGQCCEQ 104
Cdd:pfam00093   1 CVQNGVVYENGETWKPDLCTICTCDDGKVLCDKI----ICPPLDCPNPRLEIPPGECCPV 56
TSP1 smart00209
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.
 142-182 1.17e-03

Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.


Pssm-ID: 214559 [Multi-domain]  Cd Length: 53  Bit Score: 36.41  E-value: 1.17e-03
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|
gi 1958791295  142 TSPWSPCSTTCGLGISTRI--------SNVNARC-WPEQESRLCNLRPCD 182
Cdd:smart00209   4 WSEWSPCSVTCGGGVQTRTrsccspppQNGGGPCtGEDVETRACNEQPCP 53
 
Name Accession Description Interval E-value
TSP1_CCN pfam19035
CCN3 Nov like TSP1 domain; This entry represents a sub-type of TSP1 domains found in ...
 138-181 1.93e-16

CCN3 Nov like TSP1 domain; This entry represents a sub-type of TSP1 domains found in matricellular CCN proteins that have an alternative disulphide binding pattern compared to the canonical TSP1 domains.


Pssm-ID: 465952  Cd Length: 44  Bit Score: 71.60  E-value: 1.93e-16
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 1958791295 138 CIAYTSPWSPCSTTCGLGISTRISNVNARCWPEQESRLCNLRPC 181
Cdd:pfam19035   1 CEEQSTEWSPCSKTCGMGVSTRVSNDNAECKLVTETRLCQLRPC 44
VWC smart00214
von Willebrand factor (vWF) type C domain;
45-103 6.98e-07

von Willebrand factor (vWF) type C domain;


Pssm-ID: 214564  Cd Length: 59  Bit Score: 45.58  E-value: 6.98e-07
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958791295   45 CVLDGVRYTNGESFQPNCRYNCTCIDG-TVGCTPLclsPRPPRLWCRQPRHVRVPGQCCE 103
Cdd:smart00214   1 CVHNGRVYNDGETWKPDPCQICTCLDGtTVLCDPV---ECPPPPDCPNPERVKPPGECCP 57
VWC pfam00093
von Willebrand factor type C domain; The high cutoff was used to prevent overlap with ...
 45-104 1.46e-06

von Willebrand factor type C domain; The high cutoff was used to prevent overlap with pfam00094.


Pssm-ID: 278520  Cd Length: 57  Bit Score: 44.72  E-value: 1.46e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958791295  45 CVLDGVRYTNGESFQPNCRYNCTCIDGTVGCTPLclspRPPRLWCRQPRHVRVPGQCCEQ 104
Cdd:pfam00093   1 CVQNGVVYENGETWKPDLCTICTCDDGKVLCDKI----ICPPLDCPNPRLEIPPGECCPV 56
TSP1_spondin pfam19028
Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an ...
 143-181 9.33e-06

Spondin-like TSP1 domain; This entry represents a sub-type of TSP1 domains that have an alternative disulphide binding pattern compared to the canonical TSP1 domain.


Pssm-ID: 465948  Cd Length: 52  Bit Score: 42.27  E-value: 9.33e-06
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 1958791295 143 SPWSPCSTTCGLGISTRISNV-------NARCWPEQESRLCNLRPC 181
Cdd:pfam19028   7 SEWSECSVTCGGGVQTRTRTVivepqngGRPCPELLERRPCNLPPC 52
TSP_1 pfam00090
Thrombospondin type 1 domain;
142-181 6.09e-04

Thrombospondin type 1 domain;


Pssm-ID: 459668 [Multi-domain]  Cd Length: 49  Bit Score: 37.01  E-value: 6.09e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
gi 1958791295 142 TSPWSPCSTTCGLGISTRISNVNARCW-------PEQESRLCNLRPC 181
Cdd:pfam00090   3 WSPWSPCSVTCGKGIQVRQRTCKSPFPggepctgDDIETQACKMDKC 49
TSP1 smart00209
Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.
 142-182 1.17e-03

Thrombospondin type 1 repeats; Type 1 repeats in thrombospondin-1 bind and activate TGF-beta.


Pssm-ID: 214559 [Multi-domain]  Cd Length: 53  Bit Score: 36.41  E-value: 1.17e-03
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|
gi 1958791295  142 TSPWSPCSTTCGLGISTRI--------SNVNARC-WPEQESRLCNLRPCD 182
Cdd:smart00209   4 WSEWSPCSVTCGGGVQTRTrsccspppQNGGGPCtGEDVETRACNEQPCP 53
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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