cAMP-dependent protein kinase type I-beta regulatory subunit isoform X2 [Rattus norvegicus]
cyclic nucleotide-binding domain-containing protein( domain architecture ID 10034975)
cyclic nucleotide-binding domain-containing protein binds cyclic nucleotides (cAMP or cGMP)
List of domain hits
Name | Accession | Description | Interval | E-value | |||
CAP_ED | cd00038 | effector domain of the CAP family of transcription factors; members include CAP (or cAMP ... |
103-218 | 2.95e-32 | |||
effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO sensor. In all cases binding of the effector leads to conformational changes and the ability to activate transcription. Cyclic nucleotide-binding domain similar to CAP are also present in cAMP- and cGMP-dependent protein kinases (cAPK and cGPK) and vertebrate cyclic nucleotide-gated ion-channels. Cyclic nucleotide-monophosphate binding domain; proteins that bind cyclic nucleotides (cAMP or cGMP) share a structural domain of about 120 residues; the best studied is the prokaryotic catabolite gene activator, CAP, where such a domain is known to be composed of three alpha-helices and a distinctive eight-stranded, antiparallel beta-barrel structure; three conserved glycine residues are thought to be essential for maintenance of the structural integrity of the beta-barrel; CooA is a homodimeric transcription factor that belongs to CAP family; cAMP- and cGMP-dependent protein kinases (cAPK and cGPK) contain two tandem copies of the cyclic nucleotide-binding domain; cAPK's are composed of two different subunits, a catalytic chain and a regulatory chain, which contains both copies of the domain; cGPK's are single chain enzymes that include the two copies of the domain in their N-terminal section; also found in vertebrate cyclic nucleotide-gated ion-channels : Pssm-ID: 237999 [Multi-domain] Cd Length: 115 Bit Score: 113.57 E-value: 2.95e-32
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CAP_ED | cd00038 | effector domain of the CAP family of transcription factors; members include CAP (or cAMP ... |
1-94 | 2.58e-23 | |||
effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO sensor. In all cases binding of the effector leads to conformational changes and the ability to activate transcription. Cyclic nucleotide-binding domain similar to CAP are also present in cAMP- and cGMP-dependent protein kinases (cAPK and cGPK) and vertebrate cyclic nucleotide-gated ion-channels. Cyclic nucleotide-monophosphate binding domain; proteins that bind cyclic nucleotides (cAMP or cGMP) share a structural domain of about 120 residues; the best studied is the prokaryotic catabolite gene activator, CAP, where such a domain is known to be composed of three alpha-helices and a distinctive eight-stranded, antiparallel beta-barrel structure; three conserved glycine residues are thought to be essential for maintenance of the structural integrity of the beta-barrel; CooA is a homodimeric transcription factor that belongs to CAP family; cAMP- and cGMP-dependent protein kinases (cAPK and cGPK) contain two tandem copies of the cyclic nucleotide-binding domain; cAPK's are composed of two different subunits, a catalytic chain and a regulatory chain, which contains both copies of the domain; cGPK's are single chain enzymes that include the two copies of the domain in their N-terminal section; also found in vertebrate cyclic nucleotide-gated ion-channels : Pssm-ID: 237999 [Multi-domain] Cd Length: 115 Bit Score: 90.46 E-value: 2.58e-23
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Name | Accession | Description | Interval | E-value | |||
CAP_ED | cd00038 | effector domain of the CAP family of transcription factors; members include CAP (or cAMP ... |
103-218 | 2.95e-32 | |||
effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO sensor. In all cases binding of the effector leads to conformational changes and the ability to activate transcription. Cyclic nucleotide-binding domain similar to CAP are also present in cAMP- and cGMP-dependent protein kinases (cAPK and cGPK) and vertebrate cyclic nucleotide-gated ion-channels. Cyclic nucleotide-monophosphate binding domain; proteins that bind cyclic nucleotides (cAMP or cGMP) share a structural domain of about 120 residues; the best studied is the prokaryotic catabolite gene activator, CAP, where such a domain is known to be composed of three alpha-helices and a distinctive eight-stranded, antiparallel beta-barrel structure; three conserved glycine residues are thought to be essential for maintenance of the structural integrity of the beta-barrel; CooA is a homodimeric transcription factor that belongs to CAP family; cAMP- and cGMP-dependent protein kinases (cAPK and cGPK) contain two tandem copies of the cyclic nucleotide-binding domain; cAPK's are composed of two different subunits, a catalytic chain and a regulatory chain, which contains both copies of the domain; cGPK's are single chain enzymes that include the two copies of the domain in their N-terminal section; also found in vertebrate cyclic nucleotide-gated ion-channels Pssm-ID: 237999 [Multi-domain] Cd Length: 115 Bit Score: 113.57 E-value: 2.95e-32
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cNMP | smart00100 | Cyclic nucleotide-monophosphate binding domain; Catabolite gene activator protein (CAP) is a ... |
103-221 | 4.01e-27 | |||
Cyclic nucleotide-monophosphate binding domain; Catabolite gene activator protein (CAP) is a prokaryotic homologue of eukaryotic cNMP-binding domains, present in ion channels, and cNMP-dependent kinases. Pssm-ID: 197516 [Multi-domain] Cd Length: 120 Bit Score: 100.55 E-value: 4.01e-27
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CAP_ED | cd00038 | effector domain of the CAP family of transcription factors; members include CAP (or cAMP ... |
1-94 | 2.58e-23 | |||
effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO sensor. In all cases binding of the effector leads to conformational changes and the ability to activate transcription. Cyclic nucleotide-binding domain similar to CAP are also present in cAMP- and cGMP-dependent protein kinases (cAPK and cGPK) and vertebrate cyclic nucleotide-gated ion-channels. Cyclic nucleotide-monophosphate binding domain; proteins that bind cyclic nucleotides (cAMP or cGMP) share a structural domain of about 120 residues; the best studied is the prokaryotic catabolite gene activator, CAP, where such a domain is known to be composed of three alpha-helices and a distinctive eight-stranded, antiparallel beta-barrel structure; three conserved glycine residues are thought to be essential for maintenance of the structural integrity of the beta-barrel; CooA is a homodimeric transcription factor that belongs to CAP family; cAMP- and cGMP-dependent protein kinases (cAPK and cGPK) contain two tandem copies of the cyclic nucleotide-binding domain; cAPK's are composed of two different subunits, a catalytic chain and a regulatory chain, which contains both copies of the domain; cGPK's are single chain enzymes that include the two copies of the domain in their N-terminal section; also found in vertebrate cyclic nucleotide-gated ion-channels Pssm-ID: 237999 [Multi-domain] Cd Length: 115 Bit Score: 90.46 E-value: 2.58e-23
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cNMP_binding | pfam00027 | Cyclic nucleotide-binding domain; This domain sensor domain can bind cAMP, cGMP, c-di-GMP, ... |
121-207 | 8.85e-21 | |||
Cyclic nucleotide-binding domain; This domain sensor domain can bind cAMP, cGMP, c-di-GMP, oxygen and 2-oxoglutarate (Matilla et. al., FEMS Microbiology Reviews, fuab043, 45, 2021, 1. https://0-doi-org.brum.beds.ac.uk/10.1093/femsre/fuab043). Pssm-ID: 459637 [Multi-domain] Cd Length: 89 Bit Score: 83.04 E-value: 8.85e-21
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cNMP | smart00100 | Cyclic nucleotide-monophosphate binding domain; Catabolite gene activator protein (CAP) is a ... |
1-99 | 2.73e-20 | |||
Cyclic nucleotide-monophosphate binding domain; Catabolite gene activator protein (CAP) is a prokaryotic homologue of eukaryotic cNMP-binding domains, present in ion channels, and cNMP-dependent kinases. Pssm-ID: 197516 [Multi-domain] Cd Length: 120 Bit Score: 82.83 E-value: 2.73e-20
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Crp | COG0664 | cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases [Signal ... |
104-207 | 7.61e-18 | |||
cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Pssm-ID: 440428 [Multi-domain] Cd Length: 207 Bit Score: 78.49 E-value: 7.61e-18
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cNMP_binding | pfam00027 | Cyclic nucleotide-binding domain; This domain sensor domain can bind cAMP, cGMP, c-di-GMP, ... |
9-84 | 1.85e-16 | |||
Cyclic nucleotide-binding domain; This domain sensor domain can bind cAMP, cGMP, c-di-GMP, oxygen and 2-oxoglutarate (Matilla et. al., FEMS Microbiology Reviews, fuab043, 45, 2021, 1. https://0-doi-org.brum.beds.ac.uk/10.1093/femsre/fuab043). Pssm-ID: 459637 [Multi-domain] Cd Length: 89 Bit Score: 71.87 E-value: 1.85e-16
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PLN02868 | PLN02868 | acyl-CoA thioesterase family protein |
96-198 | 2.09e-11 | |||
acyl-CoA thioesterase family protein Pssm-ID: 178459 [Multi-domain] Cd Length: 413 Bit Score: 62.43 E-value: 2.09e-11
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Crp | COG0664 | cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases [Signal ... |
9-83 | 7.48e-11 | |||
cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Pssm-ID: 440428 [Multi-domain] Cd Length: 207 Bit Score: 59.62 E-value: 7.48e-11
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cyc_nuc_ocin | TIGR03896 | bacteriocin-type transport-associated protein; Members of this protein family are ... |
122-189 | 2.33e-05 | |||
bacteriocin-type transport-associated protein; Members of this protein family are uncharacterized and contain two copies of the cyclic nucleotide-binding domain pfam00027. Members are restricted to select cyanobacteria but are found regularly in association with a transport operon that, in turn, is associated with the production of putative bacteriocins. The models describing the transport operon are TIGR03794, TIGR03796, and TIGR03797. Pssm-ID: 274839 [Multi-domain] Cd Length: 317 Bit Score: 44.50 E-value: 2.33e-05
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PRK11753 | PRK11753 | cAMP-activated global transcriptional regulator CRP; |
11-91 | 5.17e-04 | |||
cAMP-activated global transcriptional regulator CRP; Pssm-ID: 236969 [Multi-domain] Cd Length: 211 Bit Score: 39.96 E-value: 5.17e-04
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cyc_nuc_ocin | TIGR03896 | bacteriocin-type transport-associated protein; Members of this protein family are ... |
9-83 | 1.44e-03 | |||
bacteriocin-type transport-associated protein; Members of this protein family are uncharacterized and contain two copies of the cyclic nucleotide-binding domain pfam00027. Members are restricted to select cyanobacteria but are found regularly in association with a transport operon that, in turn, is associated with the production of putative bacteriocins. The models describing the transport operon are TIGR03794, TIGR03796, and TIGR03797. Pssm-ID: 274839 [Multi-domain] Cd Length: 317 Bit Score: 39.11 E-value: 1.44e-03
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Name | Accession | Description | Interval | E-value | ||||
CAP_ED | cd00038 | effector domain of the CAP family of transcription factors; members include CAP (or cAMP ... |
103-218 | 2.95e-32 | ||||
effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO sensor. In all cases binding of the effector leads to conformational changes and the ability to activate transcription. Cyclic nucleotide-binding domain similar to CAP are also present in cAMP- and cGMP-dependent protein kinases (cAPK and cGPK) and vertebrate cyclic nucleotide-gated ion-channels. Cyclic nucleotide-monophosphate binding domain; proteins that bind cyclic nucleotides (cAMP or cGMP) share a structural domain of about 120 residues; the best studied is the prokaryotic catabolite gene activator, CAP, where such a domain is known to be composed of three alpha-helices and a distinctive eight-stranded, antiparallel beta-barrel structure; three conserved glycine residues are thought to be essential for maintenance of the structural integrity of the beta-barrel; CooA is a homodimeric transcription factor that belongs to CAP family; cAMP- and cGMP-dependent protein kinases (cAPK and cGPK) contain two tandem copies of the cyclic nucleotide-binding domain; cAPK's are composed of two different subunits, a catalytic chain and a regulatory chain, which contains both copies of the domain; cGPK's are single chain enzymes that include the two copies of the domain in their N-terminal section; also found in vertebrate cyclic nucleotide-gated ion-channels Pssm-ID: 237999 [Multi-domain] Cd Length: 115 Bit Score: 113.57 E-value: 2.95e-32
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cNMP | smart00100 | Cyclic nucleotide-monophosphate binding domain; Catabolite gene activator protein (CAP) is a ... |
103-221 | 4.01e-27 | ||||
Cyclic nucleotide-monophosphate binding domain; Catabolite gene activator protein (CAP) is a prokaryotic homologue of eukaryotic cNMP-binding domains, present in ion channels, and cNMP-dependent kinases. Pssm-ID: 197516 [Multi-domain] Cd Length: 120 Bit Score: 100.55 E-value: 4.01e-27
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CAP_ED | cd00038 | effector domain of the CAP family of transcription factors; members include CAP (or cAMP ... |
1-94 | 2.58e-23 | ||||
effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO sensor. In all cases binding of the effector leads to conformational changes and the ability to activate transcription. Cyclic nucleotide-binding domain similar to CAP are also present in cAMP- and cGMP-dependent protein kinases (cAPK and cGPK) and vertebrate cyclic nucleotide-gated ion-channels. Cyclic nucleotide-monophosphate binding domain; proteins that bind cyclic nucleotides (cAMP or cGMP) share a structural domain of about 120 residues; the best studied is the prokaryotic catabolite gene activator, CAP, where such a domain is known to be composed of three alpha-helices and a distinctive eight-stranded, antiparallel beta-barrel structure; three conserved glycine residues are thought to be essential for maintenance of the structural integrity of the beta-barrel; CooA is a homodimeric transcription factor that belongs to CAP family; cAMP- and cGMP-dependent protein kinases (cAPK and cGPK) contain two tandem copies of the cyclic nucleotide-binding domain; cAPK's are composed of two different subunits, a catalytic chain and a regulatory chain, which contains both copies of the domain; cGPK's are single chain enzymes that include the two copies of the domain in their N-terminal section; also found in vertebrate cyclic nucleotide-gated ion-channels Pssm-ID: 237999 [Multi-domain] Cd Length: 115 Bit Score: 90.46 E-value: 2.58e-23
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cNMP_binding | pfam00027 | Cyclic nucleotide-binding domain; This domain sensor domain can bind cAMP, cGMP, c-di-GMP, ... |
121-207 | 8.85e-21 | ||||
Cyclic nucleotide-binding domain; This domain sensor domain can bind cAMP, cGMP, c-di-GMP, oxygen and 2-oxoglutarate (Matilla et. al., FEMS Microbiology Reviews, fuab043, 45, 2021, 1. https://0-doi-org.brum.beds.ac.uk/10.1093/femsre/fuab043). Pssm-ID: 459637 [Multi-domain] Cd Length: 89 Bit Score: 83.04 E-value: 8.85e-21
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cNMP | smart00100 | Cyclic nucleotide-monophosphate binding domain; Catabolite gene activator protein (CAP) is a ... |
1-99 | 2.73e-20 | ||||
Cyclic nucleotide-monophosphate binding domain; Catabolite gene activator protein (CAP) is a prokaryotic homologue of eukaryotic cNMP-binding domains, present in ion channels, and cNMP-dependent kinases. Pssm-ID: 197516 [Multi-domain] Cd Length: 120 Bit Score: 82.83 E-value: 2.73e-20
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Crp | COG0664 | cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases [Signal ... |
104-207 | 7.61e-18 | ||||
cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Pssm-ID: 440428 [Multi-domain] Cd Length: 207 Bit Score: 78.49 E-value: 7.61e-18
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cNMP_binding | pfam00027 | Cyclic nucleotide-binding domain; This domain sensor domain can bind cAMP, cGMP, c-di-GMP, ... |
9-84 | 1.85e-16 | ||||
Cyclic nucleotide-binding domain; This domain sensor domain can bind cAMP, cGMP, c-di-GMP, oxygen and 2-oxoglutarate (Matilla et. al., FEMS Microbiology Reviews, fuab043, 45, 2021, 1. https://0-doi-org.brum.beds.ac.uk/10.1093/femsre/fuab043). Pssm-ID: 459637 [Multi-domain] Cd Length: 89 Bit Score: 71.87 E-value: 1.85e-16
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PLN02868 | PLN02868 | acyl-CoA thioesterase family protein |
96-198 | 2.09e-11 | ||||
acyl-CoA thioesterase family protein Pssm-ID: 178459 [Multi-domain] Cd Length: 413 Bit Score: 62.43 E-value: 2.09e-11
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Crp | COG0664 | cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases [Signal ... |
9-83 | 7.48e-11 | ||||
cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Pssm-ID: 440428 [Multi-domain] Cd Length: 207 Bit Score: 59.62 E-value: 7.48e-11
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cyc_nuc_ocin | TIGR03896 | bacteriocin-type transport-associated protein; Members of this protein family are ... |
122-189 | 2.33e-05 | ||||
bacteriocin-type transport-associated protein; Members of this protein family are uncharacterized and contain two copies of the cyclic nucleotide-binding domain pfam00027. Members are restricted to select cyanobacteria but are found regularly in association with a transport operon that, in turn, is associated with the production of putative bacteriocins. The models describing the transport operon are TIGR03794, TIGR03796, and TIGR03797. Pssm-ID: 274839 [Multi-domain] Cd Length: 317 Bit Score: 44.50 E-value: 2.33e-05
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PRK11753 | PRK11753 | cAMP-activated global transcriptional regulator CRP; |
130-214 | 5.76e-05 | ||||
cAMP-activated global transcriptional regulator CRP; Pssm-ID: 236969 [Multi-domain] Cd Length: 211 Bit Score: 42.66 E-value: 5.76e-05
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PLN03192 | PLN03192 | Voltage-dependent potassium channel; Provisional |
128-186 | 8.94e-05 | ||||
Voltage-dependent potassium channel; Provisional Pssm-ID: 215625 [Multi-domain] Cd Length: 823 Bit Score: 42.93 E-value: 8.94e-05
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cyc_nuc_ocin | TIGR03896 | bacteriocin-type transport-associated protein; Members of this protein family are ... |
9-200 | 1.51e-04 | ||||
bacteriocin-type transport-associated protein; Members of this protein family are uncharacterized and contain two copies of the cyclic nucleotide-binding domain pfam00027. Members are restricted to select cyanobacteria but are found regularly in association with a transport operon that, in turn, is associated with the production of putative bacteriocins. The models describing the transport operon are TIGR03794, TIGR03796, and TIGR03797. Pssm-ID: 274839 [Multi-domain] Cd Length: 317 Bit Score: 41.80 E-value: 1.51e-04
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PRK11753 | PRK11753 | cAMP-activated global transcriptional regulator CRP; |
11-91 | 5.17e-04 | ||||
cAMP-activated global transcriptional regulator CRP; Pssm-ID: 236969 [Multi-domain] Cd Length: 211 Bit Score: 39.96 E-value: 5.17e-04
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cyc_nuc_ocin | TIGR03896 | bacteriocin-type transport-associated protein; Members of this protein family are ... |
9-83 | 1.44e-03 | ||||
bacteriocin-type transport-associated protein; Members of this protein family are uncharacterized and contain two copies of the cyclic nucleotide-binding domain pfam00027. Members are restricted to select cyanobacteria but are found regularly in association with a transport operon that, in turn, is associated with the production of putative bacteriocins. The models describing the transport operon are TIGR03794, TIGR03796, and TIGR03797. Pssm-ID: 274839 [Multi-domain] Cd Length: 317 Bit Score: 39.11 E-value: 1.44e-03
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Blast search parameters | ||||
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