NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|1958677206|ref|XP_038948354|]
View 

uncharacterized protein KIAA0232 homolog isoform X3 [Rattus norvegicus]

Protein Classification

DUF4603 domain-containing protein( domain architecture ID 10634086)

DUF4603 domain-containing protein similar to Homo sapiens protein KIAA0232

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
DUF4603 pfam15376
Domain of unknown function (DUF4603); This protein family is a domain of unknown function. In ...
 23-1302 0e+00

Domain of unknown function (DUF4603); This protein family is a domain of unknown function. In particular, this domain lies at the C-terminal end of a protein found in eukaryotes.


:

Pssm-ID: 464684  Cd Length: 1293  Bit Score: 2210.01  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958677206   23 GPVSVSDMSLLHALGPVQTWLGQELEKCGIDAMIYSRYILSLLLHDSYDYDLQEQENDI-LGWEKGAYKKWGRSKKKCSD 101
Cdd:pfam15376    1 GPLPASEMSLLQSLGPVQTWLGQELEKCGIDAMIYTRYVLSLLLHDSYDYDLQDQENDIfLGWEKGAGKKWGKSKKKGTD 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958677206  102 LTLEEMKKQAAVQCLRSASDESSGIETLVEELCCRLKDLQSEQ--EEKIHKKLEGSPSPEAELSPTAKDQVEMYYEAFPP 179
Cdd:pfam15376   81 LSLEEMKKQAAVQCLRSASDENSGIESLVEELCSKLKDLQNKQkeEKKINKKSEGSQSPERDESPSSKDQVEMYYEAFPP 160

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958677206  180 LSEKPVCLQEIMTVWNKSKPCSYSSSSSSsTVPPASTDPSSPKDCNSESEAVRERSSAASILTHEKAQSR--SRHEENKL 257
Cdd:pfam15376  161 LSEKPVCLQEIMTVWNKAKACSYSSSSSS-AAPQTSTDTSSPKDCNSEGEATKERNSEAPATTSERTQQRrsKKEKENRF 239

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958677206  258 SHSTIEEKPALY-KKQIRHKPEGKIRPRSWSSGSSEAGSSSSGNQGELKASMKYVKVRHKARE-IRNKKGRNGQSRQSLK 335
Cdd:pfam15376  240 HNGAAEEKSAVHsKKQVRHRSEGKYRPRSWSSGSSEAGSSSSGNQGDMKTSIKFVKVRHKSREaVRNKKGRNGQVKLALK 319

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958677206  336 HCGKAERGVHAGSSSSSSSSSSSngsiRQLCKRGKRPAKETgRSDSGNTAVKDLYVESRSNKEYKEEPLWYTEPIAEYFV 415
Cdd:pfam15376  320 VIDKEERRNAGGSSSSASGGSIK----QQLCKKGKRPLKEI-RKDPGWVEGKESGGEARNKKEYMEEPLWYTEPITEYFV 394

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958677206  416 PLSRKSKLETTYRNREDTSALTA--EAVEDLSDSVRGLCISNSNIHRTYLAAGTFIDGHFVEMPAVINEDIDLAGTSLCS 493
Cdd:pfam15376  395 PLSRKSKLETKYRSKEDSPDGFAlsIDVEELSERVQGICIANSNIQRAYLAAGTFIDGHFVEMPAEGNEAADLNGTSSCP 474

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958677206  494 LPEDNKYLDDIHLSELTHFYEVDIDQSMLDPGASETMQgESRILNMIRQKSKENTDFEAECCIVLDGMELQGERAIWTDS 573
Cdd:pfam15376  475 QPEDNKDLDDEHLSEFTHFYEVDIYQSILDPSASDSVQ-ESRILNMIRQKSKEQRDFEAECCIVLDGLELQGESAIRADS 553

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958677206  574 TSPVGAEGFFLQDLGNLAQFWECCS-SSSGDADGESFGGDSPVRLSPILDSTILSSHMLAGNQE-PFSNINEGSGIN-SC 650
Cdd:pfam15376  554 TSASGAEGFLMQDLENIAQVWECCSsSSSEDADGESFGGDSPIRLSPLLDSVSFNLSKLSGNQEeLFSEANEGSGLNsSC 633

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958677206  651 FSVFEVQCSNSVLPFSFETLNLGSEHTDSS--ANMLGKTQSRLLIWTKNSAFEENEHCSNLSTRTCSPWSHSEEARSDNE 728
Cdd:pfam15376  634 FSLFEVQYDSSTFPFPRDSLTLGHENTDSSscLNPLGNKQSRLLIWTKNSAFDETEHCSNLSTRTCSPWSHSEETRSDNE 713

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958677206  729 TLNLQFEESTQFTAEDINYVVPRVSSDFVDEELLDFLQDETCQQNSRTLGEIPTLVFKKRSKLESVCGIQLEQKaESKNF 808
Cdd:pfam15376  714 QFNAQAEESAQFGNEEINCVIPPLSSTYLEEELLDFLQEESCHQEEVSVSTASNQTFKKKSKLESVCGIALEQD-ESKQY 792

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958677206  809 ETTQ-ACGESSPHGDGYSSGVIKDIWTKMVGRSSVAAAETERAGEELFSTDVSNY-CCCLDTEAKMETLQEPSRAVQRSE 886
Cdd:pfam15376  793 ESTGvFSDNSNQQGDDYSSGIIKDIWTAIGDRDSVITLGAEKMDEGLFSEEVNSYcCCCLDVEAKGEPLQEQKKAVQRSE 872

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958677206  887 YHLWEGQKENVEKRAFVSSELSKVDGGDYTTPSKPWDVAQDKENTFILGGVYGELKTFNSDGEWAVVPPGHTKGSLLQCA 966
Cdd:pfam15376  873 YHLWEGQKENLEEQALAKNELSKVDGGDYTTPSKPWDVNSDKESTFILGGVYGELKTFSSDGEWAVVPPSDSRGSLLQCA 952

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958677206  967 ASDVVTIAGTDVFMTPGNSFAPGHRQLWKPFVSFEQNDMP-KSGENGLNKGFSFIFHEDLLGACSNFQVEDPGLEYSFSS 1045
Cdd:pfam15376  953 ASDVVTIAGTDVFMNTGNCFAPGHRPLWRPLVSFGQNEQAiKGGGDGLNKGFSFIFHEDLLGSCGNFRGEEPGLEYPFSS 1032

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958677206 1046 FDLSNPFSQVLHVECSFEPEGIASFSPSFKPKSILCSDSDSEVFHPRICGVDRTQYRAIRISPRTHFRPISASELSPAGG 1125
Cdd:pfam15376 1033 FDLNNPFSQVLHVECSFEPEDIASFSPGFKPKSILCSDSENEVFHPRIYGINRTQYRAIRISPRTHFRPISASELSPGGG 1112

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958677206 1126 SESEFESEKDEANIPIPSQVDVFEDPQADLKPLEEDAEKEGHYYGKLELESGKFLPRLKKSGMEKSAQTSLDSQEEAAGI 1205
Cdd:pfam15376 1113 SESEAESEKEEASIPVLSQVDVFDDPQADLKPLEEDAECEGPYYGKSELESGKFLPRLKKSGMEKSAQTSLDSQEGSGGL 1192

                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958677206 1206 LPVGKQSQCLECNFNESL-GINLESSTANCKIMTQCEEEMNG---FCSCKAGCQFPACEDNPVSSGQLEEFPVLNTDVQE 1281
Cdd:pfam15376 1193 LPIAEQEICLDCSIAASLeSISTEGSKTNCKIGEPQKEESSGekeFCSCKAACQIPKYGKAYDFAGDLPEFPLLNIDLQG 1272

                         1290      1300
                   ....*....|....*....|.
gi 1958677206 1282 VTRNQEKQSWWEKALYSPLFP 1302
Cdd:pfam15376 1273 GTGSQQEECWWQKALCSPLFP 1293
 
Name Accession Description Interval E-value
DUF4603 pfam15376
Domain of unknown function (DUF4603); This protein family is a domain of unknown function. In ...
 23-1302 0e+00

Domain of unknown function (DUF4603); This protein family is a domain of unknown function. In particular, this domain lies at the C-terminal end of a protein found in eukaryotes.


Pssm-ID: 464684  Cd Length: 1293  Bit Score: 2210.01  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958677206   23 GPVSVSDMSLLHALGPVQTWLGQELEKCGIDAMIYSRYILSLLLHDSYDYDLQEQENDI-LGWEKGAYKKWGRSKKKCSD 101
Cdd:pfam15376    1 GPLPASEMSLLQSLGPVQTWLGQELEKCGIDAMIYTRYVLSLLLHDSYDYDLQDQENDIfLGWEKGAGKKWGKSKKKGTD 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958677206  102 LTLEEMKKQAAVQCLRSASDESSGIETLVEELCCRLKDLQSEQ--EEKIHKKLEGSPSPEAELSPTAKDQVEMYYEAFPP 179
Cdd:pfam15376   81 LSLEEMKKQAAVQCLRSASDENSGIESLVEELCSKLKDLQNKQkeEKKINKKSEGSQSPERDESPSSKDQVEMYYEAFPP 160

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958677206  180 LSEKPVCLQEIMTVWNKSKPCSYSSSSSSsTVPPASTDPSSPKDCNSESEAVRERSSAASILTHEKAQSR--SRHEENKL 257
Cdd:pfam15376  161 LSEKPVCLQEIMTVWNKAKACSYSSSSSS-AAPQTSTDTSSPKDCNSEGEATKERNSEAPATTSERTQQRrsKKEKENRF 239

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958677206  258 SHSTIEEKPALY-KKQIRHKPEGKIRPRSWSSGSSEAGSSSSGNQGELKASMKYVKVRHKARE-IRNKKGRNGQSRQSLK 335
Cdd:pfam15376  240 HNGAAEEKSAVHsKKQVRHRSEGKYRPRSWSSGSSEAGSSSSGNQGDMKTSIKFVKVRHKSREaVRNKKGRNGQVKLALK 319

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958677206  336 HCGKAERGVHAGSSSSSSSSSSSngsiRQLCKRGKRPAKETgRSDSGNTAVKDLYVESRSNKEYKEEPLWYTEPIAEYFV 415
Cdd:pfam15376  320 VIDKEERRNAGGSSSSASGGSIK----QQLCKKGKRPLKEI-RKDPGWVEGKESGGEARNKKEYMEEPLWYTEPITEYFV 394

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958677206  416 PLSRKSKLETTYRNREDTSALTA--EAVEDLSDSVRGLCISNSNIHRTYLAAGTFIDGHFVEMPAVINEDIDLAGTSLCS 493
Cdd:pfam15376  395 PLSRKSKLETKYRSKEDSPDGFAlsIDVEELSERVQGICIANSNIQRAYLAAGTFIDGHFVEMPAEGNEAADLNGTSSCP 474

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958677206  494 LPEDNKYLDDIHLSELTHFYEVDIDQSMLDPGASETMQgESRILNMIRQKSKENTDFEAECCIVLDGMELQGERAIWTDS 573
Cdd:pfam15376  475 QPEDNKDLDDEHLSEFTHFYEVDIYQSILDPSASDSVQ-ESRILNMIRQKSKEQRDFEAECCIVLDGLELQGESAIRADS 553

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958677206  574 TSPVGAEGFFLQDLGNLAQFWECCS-SSSGDADGESFGGDSPVRLSPILDSTILSSHMLAGNQE-PFSNINEGSGIN-SC 650
Cdd:pfam15376  554 TSASGAEGFLMQDLENIAQVWECCSsSSSEDADGESFGGDSPIRLSPLLDSVSFNLSKLSGNQEeLFSEANEGSGLNsSC 633

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958677206  651 FSVFEVQCSNSVLPFSFETLNLGSEHTDSS--ANMLGKTQSRLLIWTKNSAFEENEHCSNLSTRTCSPWSHSEEARSDNE 728
Cdd:pfam15376  634 FSLFEVQYDSSTFPFPRDSLTLGHENTDSSscLNPLGNKQSRLLIWTKNSAFDETEHCSNLSTRTCSPWSHSEETRSDNE 713

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958677206  729 TLNLQFEESTQFTAEDINYVVPRVSSDFVDEELLDFLQDETCQQNSRTLGEIPTLVFKKRSKLESVCGIQLEQKaESKNF 808
Cdd:pfam15376  714 QFNAQAEESAQFGNEEINCVIPPLSSTYLEEELLDFLQEESCHQEEVSVSTASNQTFKKKSKLESVCGIALEQD-ESKQY 792

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958677206  809 ETTQ-ACGESSPHGDGYSSGVIKDIWTKMVGRSSVAAAETERAGEELFSTDVSNY-CCCLDTEAKMETLQEPSRAVQRSE 886
Cdd:pfam15376  793 ESTGvFSDNSNQQGDDYSSGIIKDIWTAIGDRDSVITLGAEKMDEGLFSEEVNSYcCCCLDVEAKGEPLQEQKKAVQRSE 872

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958677206  887 YHLWEGQKENVEKRAFVSSELSKVDGGDYTTPSKPWDVAQDKENTFILGGVYGELKTFNSDGEWAVVPPGHTKGSLLQCA 966
Cdd:pfam15376  873 YHLWEGQKENLEEQALAKNELSKVDGGDYTTPSKPWDVNSDKESTFILGGVYGELKTFSSDGEWAVVPPSDSRGSLLQCA 952

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958677206  967 ASDVVTIAGTDVFMTPGNSFAPGHRQLWKPFVSFEQNDMP-KSGENGLNKGFSFIFHEDLLGACSNFQVEDPGLEYSFSS 1045
Cdd:pfam15376  953 ASDVVTIAGTDVFMNTGNCFAPGHRPLWRPLVSFGQNEQAiKGGGDGLNKGFSFIFHEDLLGSCGNFRGEEPGLEYPFSS 1032

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958677206 1046 FDLSNPFSQVLHVECSFEPEGIASFSPSFKPKSILCSDSDSEVFHPRICGVDRTQYRAIRISPRTHFRPISASELSPAGG 1125
Cdd:pfam15376 1033 FDLNNPFSQVLHVECSFEPEDIASFSPGFKPKSILCSDSENEVFHPRIYGINRTQYRAIRISPRTHFRPISASELSPGGG 1112

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958677206 1126 SESEFESEKDEANIPIPSQVDVFEDPQADLKPLEEDAEKEGHYYGKLELESGKFLPRLKKSGMEKSAQTSLDSQEEAAGI 1205
Cdd:pfam15376 1113 SESEAESEKEEASIPVLSQVDVFDDPQADLKPLEEDAECEGPYYGKSELESGKFLPRLKKSGMEKSAQTSLDSQEGSGGL 1192

                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958677206 1206 LPVGKQSQCLECNFNESL-GINLESSTANCKIMTQCEEEMNG---FCSCKAGCQFPACEDNPVSSGQLEEFPVLNTDVQE 1281
Cdd:pfam15376 1193 LPIAEQEICLDCSIAASLeSISTEGSKTNCKIGEPQKEESSGekeFCSCKAACQIPKYGKAYDFAGDLPEFPLLNIDLQG 1272

                         1290      1300
                   ....*....|....*....|.
gi 1958677206 1282 VTRNQEKQSWWEKALYSPLFP 1302
Cdd:pfam15376 1273 GTGSQQEECWWQKALCSPLFP 1293
 
Name Accession Description Interval E-value
DUF4603 pfam15376
Domain of unknown function (DUF4603); This protein family is a domain of unknown function. In ...
 23-1302 0e+00

Domain of unknown function (DUF4603); This protein family is a domain of unknown function. In particular, this domain lies at the C-terminal end of a protein found in eukaryotes.


Pssm-ID: 464684  Cd Length: 1293  Bit Score: 2210.01  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958677206   23 GPVSVSDMSLLHALGPVQTWLGQELEKCGIDAMIYSRYILSLLLHDSYDYDLQEQENDI-LGWEKGAYKKWGRSKKKCSD 101
Cdd:pfam15376    1 GPLPASEMSLLQSLGPVQTWLGQELEKCGIDAMIYTRYVLSLLLHDSYDYDLQDQENDIfLGWEKGAGKKWGKSKKKGTD 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958677206  102 LTLEEMKKQAAVQCLRSASDESSGIETLVEELCCRLKDLQSEQ--EEKIHKKLEGSPSPEAELSPTAKDQVEMYYEAFPP 179
Cdd:pfam15376   81 LSLEEMKKQAAVQCLRSASDENSGIESLVEELCSKLKDLQNKQkeEKKINKKSEGSQSPERDESPSSKDQVEMYYEAFPP 160

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958677206  180 LSEKPVCLQEIMTVWNKSKPCSYSSSSSSsTVPPASTDPSSPKDCNSESEAVRERSSAASILTHEKAQSR--SRHEENKL 257
Cdd:pfam15376  161 LSEKPVCLQEIMTVWNKAKACSYSSSSSS-AAPQTSTDTSSPKDCNSEGEATKERNSEAPATTSERTQQRrsKKEKENRF 239

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958677206  258 SHSTIEEKPALY-KKQIRHKPEGKIRPRSWSSGSSEAGSSSSGNQGELKASMKYVKVRHKARE-IRNKKGRNGQSRQSLK 335
Cdd:pfam15376  240 HNGAAEEKSAVHsKKQVRHRSEGKYRPRSWSSGSSEAGSSSSGNQGDMKTSIKFVKVRHKSREaVRNKKGRNGQVKLALK 319

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958677206  336 HCGKAERGVHAGSSSSSSSSSSSngsiRQLCKRGKRPAKETgRSDSGNTAVKDLYVESRSNKEYKEEPLWYTEPIAEYFV 415
Cdd:pfam15376  320 VIDKEERRNAGGSSSSASGGSIK----QQLCKKGKRPLKEI-RKDPGWVEGKESGGEARNKKEYMEEPLWYTEPITEYFV 394

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958677206  416 PLSRKSKLETTYRNREDTSALTA--EAVEDLSDSVRGLCISNSNIHRTYLAAGTFIDGHFVEMPAVINEDIDLAGTSLCS 493
Cdd:pfam15376  395 PLSRKSKLETKYRSKEDSPDGFAlsIDVEELSERVQGICIANSNIQRAYLAAGTFIDGHFVEMPAEGNEAADLNGTSSCP 474

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958677206  494 LPEDNKYLDDIHLSELTHFYEVDIDQSMLDPGASETMQgESRILNMIRQKSKENTDFEAECCIVLDGMELQGERAIWTDS 573
Cdd:pfam15376  475 QPEDNKDLDDEHLSEFTHFYEVDIYQSILDPSASDSVQ-ESRILNMIRQKSKEQRDFEAECCIVLDGLELQGESAIRADS 553

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958677206  574 TSPVGAEGFFLQDLGNLAQFWECCS-SSSGDADGESFGGDSPVRLSPILDSTILSSHMLAGNQE-PFSNINEGSGIN-SC 650
Cdd:pfam15376  554 TSASGAEGFLMQDLENIAQVWECCSsSSSEDADGESFGGDSPIRLSPLLDSVSFNLSKLSGNQEeLFSEANEGSGLNsSC 633

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958677206  651 FSVFEVQCSNSVLPFSFETLNLGSEHTDSS--ANMLGKTQSRLLIWTKNSAFEENEHCSNLSTRTCSPWSHSEEARSDNE 728
Cdd:pfam15376  634 FSLFEVQYDSSTFPFPRDSLTLGHENTDSSscLNPLGNKQSRLLIWTKNSAFDETEHCSNLSTRTCSPWSHSEETRSDNE 713

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958677206  729 TLNLQFEESTQFTAEDINYVVPRVSSDFVDEELLDFLQDETCQQNSRTLGEIPTLVFKKRSKLESVCGIQLEQKaESKNF 808
Cdd:pfam15376  714 QFNAQAEESAQFGNEEINCVIPPLSSTYLEEELLDFLQEESCHQEEVSVSTASNQTFKKKSKLESVCGIALEQD-ESKQY 792

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958677206  809 ETTQ-ACGESSPHGDGYSSGVIKDIWTKMVGRSSVAAAETERAGEELFSTDVSNY-CCCLDTEAKMETLQEPSRAVQRSE 886
Cdd:pfam15376  793 ESTGvFSDNSNQQGDDYSSGIIKDIWTAIGDRDSVITLGAEKMDEGLFSEEVNSYcCCCLDVEAKGEPLQEQKKAVQRSE 872

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958677206  887 YHLWEGQKENVEKRAFVSSELSKVDGGDYTTPSKPWDVAQDKENTFILGGVYGELKTFNSDGEWAVVPPGHTKGSLLQCA 966
Cdd:pfam15376  873 YHLWEGQKENLEEQALAKNELSKVDGGDYTTPSKPWDVNSDKESTFILGGVYGELKTFSSDGEWAVVPPSDSRGSLLQCA 952

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958677206  967 ASDVVTIAGTDVFMTPGNSFAPGHRQLWKPFVSFEQNDMP-KSGENGLNKGFSFIFHEDLLGACSNFQVEDPGLEYSFSS 1045
Cdd:pfam15376  953 ASDVVTIAGTDVFMNTGNCFAPGHRPLWRPLVSFGQNEQAiKGGGDGLNKGFSFIFHEDLLGSCGNFRGEEPGLEYPFSS 1032

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958677206 1046 FDLSNPFSQVLHVECSFEPEGIASFSPSFKPKSILCSDSDSEVFHPRICGVDRTQYRAIRISPRTHFRPISASELSPAGG 1125
Cdd:pfam15376 1033 FDLNNPFSQVLHVECSFEPEDIASFSPGFKPKSILCSDSENEVFHPRIYGINRTQYRAIRISPRTHFRPISASELSPGGG 1112

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958677206 1126 SESEFESEKDEANIPIPSQVDVFEDPQADLKPLEEDAEKEGHYYGKLELESGKFLPRLKKSGMEKSAQTSLDSQEEAAGI 1205
Cdd:pfam15376 1113 SESEAESEKEEASIPVLSQVDVFDDPQADLKPLEEDAECEGPYYGKSELESGKFLPRLKKSGMEKSAQTSLDSQEGSGGL 1192

                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958677206 1206 LPVGKQSQCLECNFNESL-GINLESSTANCKIMTQCEEEMNG---FCSCKAGCQFPACEDNPVSSGQLEEFPVLNTDVQE 1281
Cdd:pfam15376 1193 LPIAEQEICLDCSIAASLeSISTEGSKTNCKIGEPQKEESSGekeFCSCKAACQIPKYGKAYDFAGDLPEFPLLNIDLQG 1272

                         1290      1300
                   ....*....|....*....|.
gi 1958677206 1282 VTRNQEKQSWWEKALYSPLFP 1302
Cdd:pfam15376 1273 GTGSQQEECWWQKALCSPLFP 1293
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH