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Conserved domains on  [gi|1958745358|ref|XP_038953277|]
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zinc finger protein 236 isoform X4 [Rattus norvegicus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
97-450 5.92e-10

FOG: Zn-finger [General function prediction only];


:

Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 63.56  E-value: 5.92e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958745358   97 FTYSCPHCGKTFQKPSQLTRHIRIHTGERPFKCSECGKAFNQK--GALQTHMIKHTGEKPHACAfcpaafsqKGNLQSHV 174
Cdd:COG5048     32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSGCDKSFSrpLELSRHLRTHHNNPSDLNS--------KSLPLSNS 103

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958745358  175 QRVHSEVKNGPTYNCTECSCVFKSLG------SLNTHISKMHMGGPPNPSSSTETAHviTATIFQTLPLQQVEAQVSSVS 248
Cdd:COG5048    104 KASSSSLSSSSSNSNDNNLLSSHSLPpssrdpQLPDLLSISNLRNNPLPGNNSSSVN--TPQSNSLHPPLPANSLSKDPS 181

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958745358  249 GEQNSQAVTDVIQQLLELSEPGPVEAQQSPQSgrQLSVTVGINQDILQQALENSGLSslpvaaPPSDCSHAQTSTVSSQS 328
Cdd:COG5048    182 SNLSLLISSNVSTSIPSSSENSPLSSSYSIPS--SSSDQNLENSSSSLPLTTNSQLS------PKSLLSQSPSSLSSSDS 253

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958745358  329 PHTSSVSAEQADPMDAEQekgqespekaekkekkilkKKSPFLPGSIREENGVRWHVCPYCTKEFRKPSDLVRHIRIHTH 408
Cdd:COG5048    254 SSSASESPRSSLPTASSQ-------------------SSSPNESDSSSEKGFSLPIKSKQCNISFSRSSPLTRHLRSVNH 314

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|
gi 1958745358  409 E----KPFKCP--QCFRAFAVKSTLTAHIKTHTGIKAFKCQY--CMKSFS 450
Cdd:COG5048    315 SgeslKPFSCPysLCGKLFSRNDALKRHILLHTSISPAKEKLlnSSSKFS 364
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
554-959 2.35e-09

FOG: Zn-finger [General function prediction only];


:

Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 62.02  E-value: 2.35e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958745358  554 EADRPYKCFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRG--FVSAGVLKAHVRTHTGLKSFKCLICNG-AFTTGGSL 630
Cdd:COG5048     29 NAPRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSGCDksFSRPLELSRHLRTHHNNPSDLNSKSLPlSNSKASSS 108

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958745358  631 RRHMGIHNDLRPYMCPYCQKTFKTSLNCKKHMKTHRYELAQQLQQHQEASSMDEESTvdqqsiqvSAPMPVEIESAELQQ 710
Cdd:COG5048    109 SLSSSSSNSNDNNLLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNNSSSVNTPQSN--------SLHPPLPANSLSKDP 180

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958745358  711 TPETVAADPESILELGPQHvvgtEDTALGQQLADQPLEADDEdgfaaSQAPLPGHMDQFEEQGTPQPSFESAgLPQGFTV 790
Cdd:COG5048    181 SSNLSLLISSNVSTSIPSS----SENSPLSSSYSIPSSSSDQ-----NLENSSSSLPLTTNSQLSPKSLLSQ-SPSSLSS 250

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958745358  791 TDTYSQQTSFPPVQQLQDSSTLESQALSTSFHQQNLLQVPSSDAINvatrllPESSQEDlDLQTHRPQFLGDSEDQSRRS 870
Cdd:COG5048    251 SDSSSSASESPRSSLPTASSQSSSPNESDSSSEKGFSLPIKSKQCN------ISFSRSS-PLTRHLRSVNHSGESLKPFS 323

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958745358  871 YRCDYCHKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKS-------HEKTHTGVKAFSCSV--CSASFTTNGS 941
Cdd:COG5048    324 CPYSLCGKLFSRNDALKRHILLHTSISPAKEKLLNSSSKFSPLLNNeppqslqQYKDLKNDKKSETLSnsCIRNFKRDSN 403

                          410
                   ....*....|....*...
gi 1958745358  942 LTRHMATHMSMKPYKCPF 959
Cdd:COG5048    404 LSLHIITHLSFRPYNCKN 421
FhaB super family cl27105
Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, ...
 1241-1517 1.32e-07

Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, secretion, and vesicular transport];


The actual alignment was detected with superfamily member COG3210:

Pssm-ID: 442443 [Multi-domain]  Cd Length: 1698  Bit Score: 57.08  E-value: 1.32e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958745358 1241 ASVSAGGDLTVSL--TDGSLATLEGIQLQLAANLVGPNVQIS--GIDASSINNITLQIDPSILQQTLQQSSLLAQPITGE 1316
Cdd:COG3210    802 GTITAAGTTAINVtgSGGTITINTATTGLTGTGDTTSGAGGSntTDTTTGTTSDGASGGGTAGANSGSLAATAASITVGS 881

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958745358 1317 SSTASQNSSLQTSDSTVPASVVIQPISGLSLQPTVTSANLTIGPLSEQDSVLTTSNTGTQDLPQVMTSQGLVSTSTGphe 1396
Cdd:COG3210    882 GGVATSTGTANAGTLTNLGTTTNAASGNGAVLATVTATGTGGGGLTGGNAAAGGTGAGNGTTALSGTQGNAGLSAAS--- 958

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958745358 1397 ITLTINNSSLSQVLAQAAGPTASSSSGSPQEITLTISELNPSNGSLPSTAPMSPSAISAQNLVMSSSGVGADASVTLTLA 1476
Cdd:COG3210    959 ASDGAGDTGASSAAGSSAVGTSANSAGSTGGVIAATGILVAGNSGTTASTTGGSGAIVAGGNGVTGTTGTASATGTGTAA 1038

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|.
gi 1958745358 1477 DTQGMLPGGLDTVTLNITSQGQQFPALLTDPSLSGQGGAGS 1517
Cdd:COG3210   1039 TAGGQNGVGVNASGISGGNAAALTASGTAGTTGGTAASNGG 1079
zf-H2C2_2 pfam13465
Zinc-finger double domain;
1085-1109 1.97e-06

Zinc-finger double domain;


:

Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 45.83  E-value: 1.97e-06
                           10        20
                   ....*....|....*....|....*
gi 1958745358 1085 DLVRHVRIHTGEKPYKCDECGKSFT 1109
Cdd:pfam13465    1 NLKRHMRTHTGEKPYKCPECGKSFK 25
zf-H2C2_2 pfam13465
Zinc-finger double domain;
1641-1665 1.84e-05

Zinc-finger double domain;


:

Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 42.74  E-value: 1.84e-05
                           10        20
                   ....*....|....*....|....*
gi 1958745358 1641 LERHSRIHTGERPFHCTLCEKAFNQ 1665
Cdd:pfam13465    2 LKRHMRTHTGEKPYKCPECGKSFKS 26
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
863-1206 4.09e-05

FOG: Zn-finger [General function prediction only];


:

Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 48.15  E-value: 4.09e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958745358  863 SEDQSRRSYRCDYCHKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSH---EKTHTGVKAFSCSVCSASFTTN 939
Cdd:COG5048     26 SLSNAPRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSGCDKSFSRPLELSrhlRTHHNNPSDLNSKSLPLSNSKA 105

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958745358  940 GSLTRHMATHMSMKPYKCPFC----EEGFRTAIHCRKHMK-RHQAVSSVASAVAETEG-------GDTCVEEDEENSDRS 1007
Cdd:COG5048    106 SSSSLSSSSSNSNDNNLLSSHslppSSRDPQLPDLLSISNlRNNPLPGNNSSSVNTPQsnslhppLPANSLSKDPSSNLS 185

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958745358 1008 ASRKPRPEVITFTEEETAQLaKIQPQESATVSEKVLVQSAAEKDRISEMKDKQAELEAEPKHANC----CTYCPKSFKKP 1083
Cdd:COG5048    186 LLISSNVSTSIPSSSENSPL-SSSYSIPSSSSDQNLENSSSSLPLTTNSQLSPKSLLSQSPSSLSssdsSSSASESPRSS 264

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958745358 1084 SDLVRHVRIH----------TGEKPYKCDECGKSFTVKSTLDCHVKT--HTGQKL--FSCHV--CSNAFSTKGSLKVHMR 1147
Cdd:COG5048    265 LPTASSQSSSpnesdsssekGFSLPIKSKQCNISFSRSSPLTRHLRSvnHSGESLkpFSCPYslCGKLFSRNDALKRHIL 344

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1958745358 1148 LHTGAKPFKCP--HCELRFRTSGRRKTHMQFHYKSDPKKARKPVTRSSSENLQSVNLLNSS 1206
Cdd:COG5048    345 LHTSISPAKEKllNSSSKFSPLLNNEPPQSLQQYKDLKNDKKSETLSNSCIRNFKRDSNLS 405
zf-H2C2_2 pfam13465
Zinc-finger double domain;
454-479 1.59e-04

Zinc-finger double domain;


:

Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 40.43  E-value: 1.59e-04
                           10        20
                   ....*....|....*....|....*.
gi 1958745358  454 SLKVHIRLHTGVRPFACPHCDKKFRT 479
Cdd:pfam13465    1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
1668-1693 2.33e-04

Zinc-finger double domain;


:

Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 39.66  E-value: 2.33e-04
                           10        20
                   ....*....|....*....|....*.
gi 1958745358 1668 ALQVHMKKHTGERPYRCDYCVMGFTQ 1693
Cdd:pfam13465    1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
SUF4-like super family cl41227
N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), ...
 1563-1611 1.89e-03

N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana SUF4 (AtSUF4), and similar proteins; Oryza sativa SUPPRESSOR OF FRI 4 (OsSUF4) is a C2H2-type zinc finger transcription factor which interacts with the major H3K36 methyltransferase SDG725 to promote H3K36me3 (tri-methylation at H3K9) establishment. The transcription factor OsSUF4 recognizes a specific 7-bp DNA element (5'-CGGAAAT-3'), which is contained in the promoter regions of many genes throughout the rice genome. Through interaction with OsSUF4, SDG725 is recruited to the promoters of key florigen genes, RICE FLOWERING LOCUS T1 (RFT1) and Heading date 3a (Hd3a), for H3K36 deposition to promote gene activation and rice plant flowering. OsSUF4 target genes include a number of genes involved in many biological processes. Flowering plant Arabidopsis SUF4 binds to a 15bp DNA element (5'-CCAAATTTTAAGTTT-3') within the promoter of the floral repressor gene FLOWERING LOCUS C (FLC) and recruits the FRI-C transcription activator complex to the FLC promoter. Although the DNA-binding element and target genes of AtSUF4 are different from those of OsSUF4, AtSUF4 is known to interact with the Arabidopsis H3K36 methyltransferase SDG8 (also known as ASHH2/EFS/SET8), and the methylation deposition mechanism mediated by the SUF4 transcription factor and H3K36 methyltransferase may be conserved in Arabidopsis and rice. Proteins in this family have two conserved C2H2-type zinc finger motifs at the N-terminus (included in this model), and a large proline-rich domain at the C-terminus; for OsSUF4, it has been shown that the N-terminal zinc-finger domain is responsible for DNA binding, and that the C-terminal domain interacts with SDG725.


The actual alignment was detected with superfamily member cd20908:

Pssm-ID: 411020 [Multi-domain]  Cd Length: 82  Bit Score: 38.69  E-value: 1.89e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*....
gi 1958745358 1563 CLDCDRAFSSAAVLMHHSKEVHGKerihgCRVCRKAFKRATHLKEHMLT 1611
Cdd:cd20908      4 CYYCDREFDDEKILIQHQKAKHFK-----CHICHKKLYTAGGLAVHCLQ 47
 
Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
97-450 5.92e-10

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 63.56  E-value: 5.92e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958745358   97 FTYSCPHCGKTFQKPSQLTRHIRIHTGERPFKCSECGKAFNQK--GALQTHMIKHTGEKPHACAfcpaafsqKGNLQSHV 174
Cdd:COG5048     32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSGCDKSFSrpLELSRHLRTHHNNPSDLNS--------KSLPLSNS 103

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958745358  175 QRVHSEVKNGPTYNCTECSCVFKSLG------SLNTHISKMHMGGPPNPSSSTETAHviTATIFQTLPLQQVEAQVSSVS 248
Cdd:COG5048    104 KASSSSLSSSSSNSNDNNLLSSHSLPpssrdpQLPDLLSISNLRNNPLPGNNSSSVN--TPQSNSLHPPLPANSLSKDPS 181

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958745358  249 GEQNSQAVTDVIQQLLELSEPGPVEAQQSPQSgrQLSVTVGINQDILQQALENSGLSslpvaaPPSDCSHAQTSTVSSQS 328
Cdd:COG5048    182 SNLSLLISSNVSTSIPSSSENSPLSSSYSIPS--SSSDQNLENSSSSLPLTTNSQLS------PKSLLSQSPSSLSSSDS 253

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958745358  329 PHTSSVSAEQADPMDAEQekgqespekaekkekkilkKKSPFLPGSIREENGVRWHVCPYCTKEFRKPSDLVRHIRIHTH 408
Cdd:COG5048    254 SSSASESPRSSLPTASSQ-------------------SSSPNESDSSSEKGFSLPIKSKQCNISFSRSSPLTRHLRSVNH 314

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|
gi 1958745358  409 E----KPFKCP--QCFRAFAVKSTLTAHIKTHTGIKAFKCQY--CMKSFS 450
Cdd:COG5048    315 SgeslKPFSCPysLCGKLFSRNDALKRHILLHTSISPAKEKLlnSSSKFS 364
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
554-959 2.35e-09

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 62.02  E-value: 2.35e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958745358  554 EADRPYKCFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRG--FVSAGVLKAHVRTHTGLKSFKCLICNG-AFTTGGSL 630
Cdd:COG5048     29 NAPRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSGCDksFSRPLELSRHLRTHHNNPSDLNSKSLPlSNSKASSS 108

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958745358  631 RRHMGIHNDLRPYMCPYCQKTFKTSLNCKKHMKTHRYELAQQLQQHQEASSMDEESTvdqqsiqvSAPMPVEIESAELQQ 710
Cdd:COG5048    109 SLSSSSSNSNDNNLLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNNSSSVNTPQSN--------SLHPPLPANSLSKDP 180

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958745358  711 TPETVAADPESILELGPQHvvgtEDTALGQQLADQPLEADDEdgfaaSQAPLPGHMDQFEEQGTPQPSFESAgLPQGFTV 790
Cdd:COG5048    181 SSNLSLLISSNVSTSIPSS----SENSPLSSSYSIPSSSSDQ-----NLENSSSSLPLTTNSQLSPKSLLSQ-SPSSLSS 250

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958745358  791 TDTYSQQTSFPPVQQLQDSSTLESQALSTSFHQQNLLQVPSSDAINvatrllPESSQEDlDLQTHRPQFLGDSEDQSRRS 870
Cdd:COG5048    251 SDSSSSASESPRSSLPTASSQSSSPNESDSSSEKGFSLPIKSKQCN------ISFSRSS-PLTRHLRSVNHSGESLKPFS 323

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958745358  871 YRCDYCHKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKS-------HEKTHTGVKAFSCSV--CSASFTTNGS 941
Cdd:COG5048    324 CPYSLCGKLFSRNDALKRHILLHTSISPAKEKLLNSSSKFSPLLNNeppqslqQYKDLKNDKKSETLSnsCIRNFKRDSN 403

                          410
                   ....*....|....*...
gi 1958745358  942 LTRHMATHMSMKPYKCPF 959
Cdd:COG5048    404 LSLHIITHLSFRPYNCKN 421
FhaB COG3210
Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, ...
 1241-1517 1.32e-07

Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 442443 [Multi-domain]  Cd Length: 1698  Bit Score: 57.08  E-value: 1.32e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958745358 1241 ASVSAGGDLTVSL--TDGSLATLEGIQLQLAANLVGPNVQIS--GIDASSINNITLQIDPSILQQTLQQSSLLAQPITGE 1316
Cdd:COG3210    802 GTITAAGTTAINVtgSGGTITINTATTGLTGTGDTTSGAGGSntTDTTTGTTSDGASGGGTAGANSGSLAATAASITVGS 881

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958745358 1317 SSTASQNSSLQTSDSTVPASVVIQPISGLSLQPTVTSANLTIGPLSEQDSVLTTSNTGTQDLPQVMTSQGLVSTSTGphe 1396
Cdd:COG3210    882 GGVATSTGTANAGTLTNLGTTTNAASGNGAVLATVTATGTGGGGLTGGNAAAGGTGAGNGTTALSGTQGNAGLSAAS--- 958

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958745358 1397 ITLTINNSSLSQVLAQAAGPTASSSSGSPQEITLTISELNPSNGSLPSTAPMSPSAISAQNLVMSSSGVGADASVTLTLA 1476
Cdd:COG3210    959 ASDGAGDTGASSAAGSSAVGTSANSAGSTGGVIAATGILVAGNSGTTASTTGGSGAIVAGGNGVTGTTGTASATGTGTAA 1038

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|.
gi 1958745358 1477 DTQGMLPGGLDTVTLNITSQGQQFPALLTDPSLSGQGGAGS 1517
Cdd:COG3210   1039 TAGGQNGVGVNASGISGGNAAALTASGTAGTTGGTAASNGG 1079
DUF5585 pfam17823
Family of unknown function (DUF5585); This is a family of unknown function found in chordata.
 1310-1553 1.26e-06

Family of unknown function (DUF5585); This is a family of unknown function found in chordata.


Pssm-ID: 465521 [Multi-domain]  Cd Length: 506  Bit Score: 53.04  E-value: 1.26e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958745358 1310 AQPITGESSTASQNSSLQTSDSTVPASVViqPISglslqPTVTSANLTIGPlseqdsvltTSNTGTQDLPQVMTSQGLVS 1389
Cdd:pfam17823  179 ASSTTAASSTTAASSAPTTAASSAPATLT--PAR-----GISTAATATGHP---------AAGTALAAVGNSSPAAGTVT 242

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958745358 1390 TSTGPHEITLTINNSSLSQVLAQAAGptaSSSSGSPQEITLTISELNPSNGSLPS-TAPMSPSA------ISAQNLVMSS 1462
Cdd:pfam17823  243 AAVGTVTPAALATLAAAAGTVASAAG---TINMGDPHARRLSPAKHMPSDTMARNpAAPMGAQAqgpiiqVSTDQPVHNT 319

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958745358 1463 SGVGADASVTLTLADTQGMLPGGLDTVTLNITSQGQQFPALLTDPSLSgqgGAGSPQVILVSHTPQPS------SAAG-- 1534
Cdd:pfam17823  320 AGEPTPSPSNTTLEPNTPKSVASTNLAVVTTTKAQAKEPSASPVPVLH---TSMIPEVEATSPTTQPSpllptqGAAGpg 396

                          250       260
                   ....*....|....*....|....
gi 1958745358 1535 -----EEIAYQVTDVSAQLSPNSQ 1553
Cdd:pfam17823  397 illapEQVATEATAGTASAGPTPR 420
zf-H2C2_2 pfam13465
Zinc-finger double domain;
1085-1109 1.97e-06

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 45.83  E-value: 1.97e-06
                           10        20
                   ....*....|....*....|....*
gi 1958745358 1085 DLVRHVRIHTGEKPYKCDECGKSFT 1109
Cdd:pfam13465    1 NLKRHMRTHTGEKPYKCPECGKSFK 25
zf-H2C2_2 pfam13465
Zinc-finger double domain;
114-138 4.99e-06

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 44.67  E-value: 4.99e-06
                           10        20
                   ....*....|....*....|....*
gi 1958745358  114 LTRHIRIHTGERPFKCSECGKAFNQ 138
Cdd:pfam13465    2 LKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
573-598 1.29e-05

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 43.51  E-value: 1.29e-05
                           10        20
                   ....*....|....*....|....*.
gi 1958745358  573 HLKQHIRSHTGEKPFKCSQCGRGFVS 598
Cdd:pfam13465    1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
1641-1665 1.84e-05

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 42.74  E-value: 1.84e-05
                           10        20
                   ....*....|....*....|....*
gi 1958745358 1641 LERHSRIHTGERPFHCTLCEKAFNQ 1665
Cdd:pfam13465    2 LKRHMRTHTGEKPYKCPECGKSFKS 26
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
863-1206 4.09e-05

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 48.15  E-value: 4.09e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958745358  863 SEDQSRRSYRCDYCHKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSH---EKTHTGVKAFSCSVCSASFTTN 939
Cdd:COG5048     26 SLSNAPRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSGCDKSFSRPLELSrhlRTHHNNPSDLNSKSLPLSNSKA 105

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958745358  940 GSLTRHMATHMSMKPYKCPFC----EEGFRTAIHCRKHMK-RHQAVSSVASAVAETEG-------GDTCVEEDEENSDRS 1007
Cdd:COG5048    106 SSSSLSSSSSNSNDNNLLSSHslppSSRDPQLPDLLSISNlRNNPLPGNNSSSVNTPQsnslhppLPANSLSKDPSSNLS 185

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958745358 1008 ASRKPRPEVITFTEEETAQLaKIQPQESATVSEKVLVQSAAEKDRISEMKDKQAELEAEPKHANC----CTYCPKSFKKP 1083
Cdd:COG5048    186 LLISSNVSTSIPSSSENSPL-SSSYSIPSSSSDQNLENSSSSLPLTTNSQLSPKSLLSQSPSSLSssdsSSSASESPRSS 264

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958745358 1084 SDLVRHVRIH----------TGEKPYKCDECGKSFTVKSTLDCHVKT--HTGQKL--FSCHV--CSNAFSTKGSLKVHMR 1147
Cdd:COG5048    265 LPTASSQSSSpnesdsssekGFSLPIKSKQCNISFSRSSPLTRHLRSvnHSGESLkpFSCPYslCGKLFSRNDALKRHIL 344

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1958745358 1148 LHTGAKPFKCP--HCELRFRTSGRRKTHMQFHYKSDPKKARKPVTRSSSENLQSVNLLNSS 1206
Cdd:COG5048    345 LHTSISPAKEKllNSSSKFSPLLNNEPPQSLQQYKDLKNDKKSETLSNSCIRNFKRDSNLS 405
PHA03255 PHA03255
BDLF3; Provisional
 1310-1447 7.51e-05

BDLF3; Provisional


Pssm-ID: 165513 [Multi-domain]  Cd Length: 234  Bit Score: 46.05  E-value: 7.51e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958745358 1310 AQPITGESSTASQNSSLQTSDSTVPASVVIQPISGLSLQPTVTSANLTIGPLSeqdsvlTTSNTGTQDLPQVMTSQGLVS 1389
Cdd:PHA03255    40 TTAVTTPSPSASGPSTNQSTTLTTTSAPITTTAILSTNTTTVTSTGTTVTPVP------TTSNASTINVTTKVTAQNITA 113

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1958745358 1390 TSTGPHEIT-LTINNSSLSQVLAQAAGPTASSSSGSPQEITLTISELNPSNGSLPsTAP 1447
Cdd:PHA03255   114 TEAGTGTSTgVTSNVTTRSSSTTSATTRITNATTLAPTLSSKGTSNATKTTAELP-TVP 171
zf-H2C2_2 pfam13465
Zinc-finger double domain;
454-479 1.59e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 40.43  E-value: 1.59e-04
                           10        20
                   ....*....|....*....|....*.
gi 1958745358  454 SLKVHIRLHTGVRPFACPHCDKKFRT 479
Cdd:pfam13465    1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
SUF4-like cd20908
N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), ...
 557-608 1.75e-04

N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana SUF4 (AtSUF4), and similar proteins; Oryza sativa SUPPRESSOR OF FRI 4 (OsSUF4) is a C2H2-type zinc finger transcription factor which interacts with the major H3K36 methyltransferase SDG725 to promote H3K36me3 (tri-methylation at H3K9) establishment. The transcription factor OsSUF4 recognizes a specific 7-bp DNA element (5'-CGGAAAT-3'), which is contained in the promoter regions of many genes throughout the rice genome. Through interaction with OsSUF4, SDG725 is recruited to the promoters of key florigen genes, RICE FLOWERING LOCUS T1 (RFT1) and Heading date 3a (Hd3a), for H3K36 deposition to promote gene activation and rice plant flowering. OsSUF4 target genes include a number of genes involved in many biological processes. Flowering plant Arabidopsis SUF4 binds to a 15bp DNA element (5'-CCAAATTTTAAGTTT-3') within the promoter of the floral repressor gene FLOWERING LOCUS C (FLC) and recruits the FRI-C transcription activator complex to the FLC promoter. Although the DNA-binding element and target genes of AtSUF4 are different from those of OsSUF4, AtSUF4 is known to interact with the Arabidopsis H3K36 methyltransferase SDG8 (also known as ASHH2/EFS/SET8), and the methylation deposition mechanism mediated by the SUF4 transcription factor and H3K36 methyltransferase may be conserved in Arabidopsis and rice. Proteins in this family have two conserved C2H2-type zinc finger motifs at the N-terminus (included in this model), and a large proline-rich domain at the C-terminus; for OsSUF4, it has been shown that the N-terminal zinc-finger domain is responsible for DNA binding, and that the C-terminal domain interacts with SDG725.


Pssm-ID: 411020 [Multi-domain]  Cd Length: 82  Bit Score: 41.77  E-value: 1.75e-04
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1958745358  557 RPYkCFYCHRAYKKSCHLKQHIRSHTgekpFKCSQCGRGFVSAGVLKAHVRT 608
Cdd:cd20908      1 KPW-CYYCDREFDDEKILIQHQKAKH----FKCHICHKKLYTAGGLAVHCLQ 47
zf-H2C2_2 pfam13465
Zinc-finger double domain;
1668-1693 2.33e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 39.66  E-value: 2.33e-04
                           10        20
                   ....*....|....*....|....*.
gi 1958745358 1668 ALQVHMKKHTGERPYRCDYCVMGFTQ 1693
Cdd:pfam13465    1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
1141-1166 4.45e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 38.89  E-value: 4.45e-04
                           10        20
                   ....*....|....*....|....*.
gi 1958745358 1141 SLKVHMRLHTGAKPFKCPHCELRFRT 1166
Cdd:pfam13465    1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
SUF4-like cd20908
N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), ...
 101-146 1.42e-03

N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana SUF4 (AtSUF4), and similar proteins; Oryza sativa SUPPRESSOR OF FRI 4 (OsSUF4) is a C2H2-type zinc finger transcription factor which interacts with the major H3K36 methyltransferase SDG725 to promote H3K36me3 (tri-methylation at H3K9) establishment. The transcription factor OsSUF4 recognizes a specific 7-bp DNA element (5'-CGGAAAT-3'), which is contained in the promoter regions of many genes throughout the rice genome. Through interaction with OsSUF4, SDG725 is recruited to the promoters of key florigen genes, RICE FLOWERING LOCUS T1 (RFT1) and Heading date 3a (Hd3a), for H3K36 deposition to promote gene activation and rice plant flowering. OsSUF4 target genes include a number of genes involved in many biological processes. Flowering plant Arabidopsis SUF4 binds to a 15bp DNA element (5'-CCAAATTTTAAGTTT-3') within the promoter of the floral repressor gene FLOWERING LOCUS C (FLC) and recruits the FRI-C transcription activator complex to the FLC promoter. Although the DNA-binding element and target genes of AtSUF4 are different from those of OsSUF4, AtSUF4 is known to interact with the Arabidopsis H3K36 methyltransferase SDG8 (also known as ASHH2/EFS/SET8), and the methylation deposition mechanism mediated by the SUF4 transcription factor and H3K36 methyltransferase may be conserved in Arabidopsis and rice. Proteins in this family have two conserved C2H2-type zinc finger motifs at the N-terminus (included in this model), and a large proline-rich domain at the C-terminus; for OsSUF4, it has been shown that the N-terminal zinc-finger domain is responsible for DNA binding, and that the C-terminal domain interacts with SDG725.


Pssm-ID: 411020 [Multi-domain]  Cd Length: 82  Bit Score: 39.08  E-value: 1.42e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*.
gi 1958745358  101 CPHCGKTFQKPSQLTRHIRIHTgerpFKCSECGKAFNQKGALQTHM 146
Cdd:cd20908      4 CYYCDREFDDEKILIQHQKAKH----FKCHICHKKLYTAGGLAVHC 45
SUF4-like cd20908
N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), ...
 1563-1611 1.89e-03

N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana SUF4 (AtSUF4), and similar proteins; Oryza sativa SUPPRESSOR OF FRI 4 (OsSUF4) is a C2H2-type zinc finger transcription factor which interacts with the major H3K36 methyltransferase SDG725 to promote H3K36me3 (tri-methylation at H3K9) establishment. The transcription factor OsSUF4 recognizes a specific 7-bp DNA element (5'-CGGAAAT-3'), which is contained in the promoter regions of many genes throughout the rice genome. Through interaction with OsSUF4, SDG725 is recruited to the promoters of key florigen genes, RICE FLOWERING LOCUS T1 (RFT1) and Heading date 3a (Hd3a), for H3K36 deposition to promote gene activation and rice plant flowering. OsSUF4 target genes include a number of genes involved in many biological processes. Flowering plant Arabidopsis SUF4 binds to a 15bp DNA element (5'-CCAAATTTTAAGTTT-3') within the promoter of the floral repressor gene FLOWERING LOCUS C (FLC) and recruits the FRI-C transcription activator complex to the FLC promoter. Although the DNA-binding element and target genes of AtSUF4 are different from those of OsSUF4, AtSUF4 is known to interact with the Arabidopsis H3K36 methyltransferase SDG8 (also known as ASHH2/EFS/SET8), and the methylation deposition mechanism mediated by the SUF4 transcription factor and H3K36 methyltransferase may be conserved in Arabidopsis and rice. Proteins in this family have two conserved C2H2-type zinc finger motifs at the N-terminus (included in this model), and a large proline-rich domain at the C-terminus; for OsSUF4, it has been shown that the N-terminal zinc-finger domain is responsible for DNA binding, and that the C-terminal domain interacts with SDG725.


Pssm-ID: 411020 [Multi-domain]  Cd Length: 82  Bit Score: 38.69  E-value: 1.89e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*....
gi 1958745358 1563 CLDCDRAFSSAAVLMHHSKEVHGKerihgCRVCRKAFKRATHLKEHMLT 1611
Cdd:cd20908      4 CYYCDREFDDEKILIQHQKAKHFK-----CHICHKKLYTAGGLAVHCLQ 47
SUF4-like cd20908
N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), ...
 1097-1146 3.40e-03

N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana SUF4 (AtSUF4), and similar proteins; Oryza sativa SUPPRESSOR OF FRI 4 (OsSUF4) is a C2H2-type zinc finger transcription factor which interacts with the major H3K36 methyltransferase SDG725 to promote H3K36me3 (tri-methylation at H3K9) establishment. The transcription factor OsSUF4 recognizes a specific 7-bp DNA element (5'-CGGAAAT-3'), which is contained in the promoter regions of many genes throughout the rice genome. Through interaction with OsSUF4, SDG725 is recruited to the promoters of key florigen genes, RICE FLOWERING LOCUS T1 (RFT1) and Heading date 3a (Hd3a), for H3K36 deposition to promote gene activation and rice plant flowering. OsSUF4 target genes include a number of genes involved in many biological processes. Flowering plant Arabidopsis SUF4 binds to a 15bp DNA element (5'-CCAAATTTTAAGTTT-3') within the promoter of the floral repressor gene FLOWERING LOCUS C (FLC) and recruits the FRI-C transcription activator complex to the FLC promoter. Although the DNA-binding element and target genes of AtSUF4 are different from those of OsSUF4, AtSUF4 is known to interact with the Arabidopsis H3K36 methyltransferase SDG8 (also known as ASHH2/EFS/SET8), and the methylation deposition mechanism mediated by the SUF4 transcription factor and H3K36 methyltransferase may be conserved in Arabidopsis and rice. Proteins in this family have two conserved C2H2-type zinc finger motifs at the N-terminus (included in this model), and a large proline-rich domain at the C-terminus; for OsSUF4, it has been shown that the N-terminal zinc-finger domain is responsible for DNA binding, and that the C-terminal domain interacts with SDG725.


Pssm-ID: 411020 [Multi-domain]  Cd Length: 82  Bit Score: 38.31  E-value: 3.40e-03
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|
gi 1958745358 1097 KPYkCDECGKSFTVKSTLDCHVKTHTgqklFSCHVCSNAFSTKGSLKVHM 1146
Cdd:cd20908      1 KPW-CYYCDREFDDEKILIQHQKAKH----FKCHICHKKLYTAGGLAVHC 45
PHA00733 PHA00733
hypothetical protein
 437-487 4.64e-03

hypothetical protein


Pssm-ID: 177301  Cd Length: 128  Bit Score: 39.09  E-value: 4.64e-03
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1958745358  437 IKAFKCQYCMKSFSTSGSLKVHIRL--HTGVrpfaCPHCDKKFRTSGHRKTHV 487
Cdd:PHA00733    71 VSPYVCPLCLMPFSSSVSLKQHIRYteHSKV----CPVCGKEFRNTDSTLDHV 119
ZnF_C2H2 smart00355
zinc finger;
99-121 9.03e-03

zinc finger;


Pssm-ID: 197676  Cd Length: 23  Bit Score: 35.13  E-value: 9.03e-03
                            10        20
                    ....*....|....*....|...
gi 1958745358    99 YSCPHCGKTFQKPSQLTRHIRIH 121
Cdd:smart00355    1 YRCPECGKVFKSKSALREHMRTH 23
 
Name Accession Description Interval E-value
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
97-450 5.92e-10

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 63.56  E-value: 5.92e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958745358   97 FTYSCPHCGKTFQKPSQLTRHIRIHTGERPFKCSECGKAFNQK--GALQTHMIKHTGEKPHACAfcpaafsqKGNLQSHV 174
Cdd:COG5048     32 RPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSGCDKSFSrpLELSRHLRTHHNNPSDLNS--------KSLPLSNS 103

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958745358  175 QRVHSEVKNGPTYNCTECSCVFKSLG------SLNTHISKMHMGGPPNPSSSTETAHviTATIFQTLPLQQVEAQVSSVS 248
Cdd:COG5048    104 KASSSSLSSSSSNSNDNNLLSSHSLPpssrdpQLPDLLSISNLRNNPLPGNNSSSVN--TPQSNSLHPPLPANSLSKDPS 181

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958745358  249 GEQNSQAVTDVIQQLLELSEPGPVEAQQSPQSgrQLSVTVGINQDILQQALENSGLSslpvaaPPSDCSHAQTSTVSSQS 328
Cdd:COG5048    182 SNLSLLISSNVSTSIPSSSENSPLSSSYSIPS--SSSDQNLENSSSSLPLTTNSQLS------PKSLLSQSPSSLSSSDS 253

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958745358  329 PHTSSVSAEQADPMDAEQekgqespekaekkekkilkKKSPFLPGSIREENGVRWHVCPYCTKEFRKPSDLVRHIRIHTH 408
Cdd:COG5048    254 SSSASESPRSSLPTASSQ-------------------SSSPNESDSSSEKGFSLPIKSKQCNISFSRSSPLTRHLRSVNH 314

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|
gi 1958745358  409 E----KPFKCP--QCFRAFAVKSTLTAHIKTHTGIKAFKCQY--CMKSFS 450
Cdd:COG5048    315 SgeslKPFSCPysLCGKLFSRNDALKRHILLHTSISPAKEKLlnSSSKFS 364
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
554-959 2.35e-09

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 62.02  E-value: 2.35e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958745358  554 EADRPYKCFYCHRAYKKSCHLKQHIRSHTGEKPFKCSQCGRG--FVSAGVLKAHVRTHTGLKSFKCLICNG-AFTTGGSL 630
Cdd:COG5048     29 NAPRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSGCDksFSRPLELSRHLRTHHNNPSDLNSKSLPlSNSKASSS 108

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958745358  631 RRHMGIHNDLRPYMCPYCQKTFKTSLNCKKHMKTHRYELAQQLQQHQEASSMDEESTvdqqsiqvSAPMPVEIESAELQQ 710
Cdd:COG5048    109 SLSSSSSNSNDNNLLSSHSLPPSSRDPQLPDLLSISNLRNNPLPGNNSSSVNTPQSN--------SLHPPLPANSLSKDP 180

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958745358  711 TPETVAADPESILELGPQHvvgtEDTALGQQLADQPLEADDEdgfaaSQAPLPGHMDQFEEQGTPQPSFESAgLPQGFTV 790
Cdd:COG5048    181 SSNLSLLISSNVSTSIPSS----SENSPLSSSYSIPSSSSDQ-----NLENSSSSLPLTTNSQLSPKSLLSQ-SPSSLSS 250

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958745358  791 TDTYSQQTSFPPVQQLQDSSTLESQALSTSFHQQNLLQVPSSDAINvatrllPESSQEDlDLQTHRPQFLGDSEDQSRRS 870
Cdd:COG5048    251 SDSSSSASESPRSSLPTASSQSSSPNESDSSSEKGFSLPIKSKQCN------ISFSRSS-PLTRHLRSVNHSGESLKPFS 323

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958745358  871 YRCDYCHKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKS-------HEKTHTGVKAFSCSV--CSASFTTNGS 941
Cdd:COG5048    324 CPYSLCGKLFSRNDALKRHILLHTSISPAKEKLLNSSSKFSPLLNNeppqslqQYKDLKNDKKSETLSnsCIRNFKRDSN 403

                          410
                   ....*....|....*...
gi 1958745358  942 LTRHMATHMSMKPYKCPF 959
Cdd:COG5048    404 LSLHIITHLSFRPYNCKN 421
FhaB COG3210
Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, ...
 1241-1517 1.32e-07

Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 442443 [Multi-domain]  Cd Length: 1698  Bit Score: 57.08  E-value: 1.32e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958745358 1241 ASVSAGGDLTVSL--TDGSLATLEGIQLQLAANLVGPNVQIS--GIDASSINNITLQIDPSILQQTLQQSSLLAQPITGE 1316
Cdd:COG3210    802 GTITAAGTTAINVtgSGGTITINTATTGLTGTGDTTSGAGGSntTDTTTGTTSDGASGGGTAGANSGSLAATAASITVGS 881

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958745358 1317 SSTASQNSSLQTSDSTVPASVVIQPISGLSLQPTVTSANLTIGPLSEQDSVLTTSNTGTQDLPQVMTSQGLVSTSTGphe 1396
Cdd:COG3210    882 GGVATSTGTANAGTLTNLGTTTNAASGNGAVLATVTATGTGGGGLTGGNAAAGGTGAGNGTTALSGTQGNAGLSAAS--- 958

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958745358 1397 ITLTINNSSLSQVLAQAAGPTASSSSGSPQEITLTISELNPSNGSLPSTAPMSPSAISAQNLVMSSSGVGADASVTLTLA 1476
Cdd:COG3210    959 ASDGAGDTGASSAAGSSAVGTSANSAGSTGGVIAATGILVAGNSGTTASTTGGSGAIVAGGNGVTGTTGTASATGTGTAA 1038

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|.
gi 1958745358 1477 DTQGMLPGGLDTVTLNITSQGQQFPALLTDPSLSGQGGAGS 1517
Cdd:COG3210   1039 TAGGQNGVGVNASGISGGNAAALTASGTAGTTGGTAASNGG 1079
DUF5585 pfam17823
Family of unknown function (DUF5585); This is a family of unknown function found in chordata.
 1310-1553 1.26e-06

Family of unknown function (DUF5585); This is a family of unknown function found in chordata.


Pssm-ID: 465521 [Multi-domain]  Cd Length: 506  Bit Score: 53.04  E-value: 1.26e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958745358 1310 AQPITGESSTASQNSSLQTSDSTVPASVViqPISglslqPTVTSANLTIGPlseqdsvltTSNTGTQDLPQVMTSQGLVS 1389
Cdd:pfam17823  179 ASSTTAASSTTAASSAPTTAASSAPATLT--PAR-----GISTAATATGHP---------AAGTALAAVGNSSPAAGTVT 242

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958745358 1390 TSTGPHEITLTINNSSLSQVLAQAAGptaSSSSGSPQEITLTISELNPSNGSLPS-TAPMSPSA------ISAQNLVMSS 1462
Cdd:pfam17823  243 AAVGTVTPAALATLAAAAGTVASAAG---TINMGDPHARRLSPAKHMPSDTMARNpAAPMGAQAqgpiiqVSTDQPVHNT 319

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958745358 1463 SGVGADASVTLTLADTQGMLPGGLDTVTLNITSQGQQFPALLTDPSLSgqgGAGSPQVILVSHTPQPS------SAAG-- 1534
Cdd:pfam17823  320 AGEPTPSPSNTTLEPNTPKSVASTNLAVVTTTKAQAKEPSASPVPVLH---TSMIPEVEATSPTTQPSpllptqGAAGpg 396

                          250       260
                   ....*....|....*....|....
gi 1958745358 1535 -----EEIAYQVTDVSAQLSPNSQ 1553
Cdd:pfam17823  397 illapEQVATEATAGTASAGPTPR 420
zf-H2C2_2 pfam13465
Zinc-finger double domain;
1085-1109 1.97e-06

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 45.83  E-value: 1.97e-06
                           10        20
                   ....*....|....*....|....*
gi 1958745358 1085 DLVRHVRIHTGEKPYKCDECGKSFT 1109
Cdd:pfam13465    1 NLKRHMRTHTGEKPYKCPECGKSFK 25
zf-H2C2_2 pfam13465
Zinc-finger double domain;
114-138 4.99e-06

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 44.67  E-value: 4.99e-06
                           10        20
                   ....*....|....*....|....*
gi 1958745358  114 LTRHIRIHTGERPFKCSECGKAFNQ 138
Cdd:pfam13465    2 LKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
573-598 1.29e-05

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 43.51  E-value: 1.29e-05
                           10        20
                   ....*....|....*....|....*.
gi 1958745358  573 HLKQHIRSHTGEKPFKCSQCGRGFVS 598
Cdd:pfam13465    1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
885-910 1.41e-05

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 43.13  E-value: 1.41e-05
                           10        20
                   ....*....|....*....|....*.
gi 1958745358  885 HLKQHVRSHTGEKPYKCKLCGRGFVS 910
Cdd:pfam13465    1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
1641-1665 1.84e-05

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 42.74  E-value: 1.84e-05
                           10        20
                   ....*....|....*....|....*
gi 1958745358 1641 LERHSRIHTGERPFHCTLCEKAFNQ 1665
Cdd:pfam13465    2 LKRHMRTHTGEKPYKCPECGKSFKS 26
Herpes_BLLF1 pfam05109
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ...
 1275-1470 3.11e-05

Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.


Pssm-ID: 282904 [Multi-domain]  Cd Length: 886  Bit Score: 49.14  E-value: 3.11e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958745358 1275 PNVQISGIDASSINNITLQIDPSILQQTLQQSSLLA----QPITGESSTASQNSSLQTSDSTVPA---SVVIQPISGLSL 1347
Cdd:pfam05109  567 PNATIPTLGKTSPTSAVTTPTPNATSPTVGETSPQAnttnHTLGGTSSTPVVTSPPKNATSAVTTgqhNITSSSTSSMSL 646

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958745358 1348 QPTVTSAnlTIGPLSEQDS-----VLTTSN-TGTQDLPQVMTSqglvstSTGPHEITlTINNSSLSQVLAQAAGPTASSS 1421
Cdd:pfam05109  647 RPSSISE--TLSPSTSDNStshmpLLTSAHpTGGENITQVTPA------STSTHHVS-TSSPAPRPGTTSQASGPGNSST 717

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1958745358 1422 SGSPQEITLTiselnpsNGSLP--STAPMSPSAISAQNLVMSSSGVGADAS 1470
Cdd:pfam05109  718 STKPGEVNVT-------KGTPPknATSPQAPSGQKTAVPTVTSTGGKANST 761
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
863-1206 4.09e-05

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 48.15  E-value: 4.09e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958745358  863 SEDQSRRSYRCDYCHKGFKKSSHLKQHVRSHTGEKPYKCKLCGRGFVSSGVLKSH---EKTHTGVKAFSCSVCSASFTTN 939
Cdd:COG5048     26 SLSNAPRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSGCDKSFSRPLELSrhlRTHHNNPSDLNSKSLPLSNSKA 105

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958745358  940 GSLTRHMATHMSMKPYKCPFC----EEGFRTAIHCRKHMK-RHQAVSSVASAVAETEG-------GDTCVEEDEENSDRS 1007
Cdd:COG5048    106 SSSSLSSSSSNSNDNNLLSSHslppSSRDPQLPDLLSISNlRNNPLPGNNSSSVNTPQsnslhppLPANSLSKDPSSNLS 185

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958745358 1008 ASRKPRPEVITFTEEETAQLaKIQPQESATVSEKVLVQSAAEKDRISEMKDKQAELEAEPKHANC----CTYCPKSFKKP 1083
Cdd:COG5048    186 LLISSNVSTSIPSSSENSPL-SSSYSIPSSSSDQNLENSSSSLPLTTNSQLSPKSLLSQSPSSLSssdsSSSASESPRSS 264

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958745358 1084 SDLVRHVRIH----------TGEKPYKCDECGKSFTVKSTLDCHVKT--HTGQKL--FSCHV--CSNAFSTKGSLKVHMR 1147
Cdd:COG5048    265 LPTASSQSSSpnesdsssekGFSLPIKSKQCNISFSRSSPLTRHLRSvnHSGESLkpFSCPYslCGKLFSRNDALKRHIL 344

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1958745358 1148 LHTGAKPFKCP--HCELRFRTSGRRKTHMQFHYKSDPKKARKPVTRSSSENLQSVNLLNSS 1206
Cdd:COG5048    345 LHTSISPAKEKllNSSSKFSPLLNNEPPQSLQQYKDLKNDKKSETLSNSCIRNFKRDSNLS 405
PHA03255 PHA03255
BDLF3; Provisional
 1310-1447 7.51e-05

BDLF3; Provisional


Pssm-ID: 165513 [Multi-domain]  Cd Length: 234  Bit Score: 46.05  E-value: 7.51e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958745358 1310 AQPITGESSTASQNSSLQTSDSTVPASVVIQPISGLSLQPTVTSANLTIGPLSeqdsvlTTSNTGTQDLPQVMTSQGLVS 1389
Cdd:PHA03255    40 TTAVTTPSPSASGPSTNQSTTLTTTSAPITTTAILSTNTTTVTSTGTTVTPVP------TTSNASTINVTTKVTAQNITA 113

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1958745358 1390 TSTGPHEIT-LTINNSSLSQVLAQAAGPTASSSSGSPQEITLTISELNPSNGSLPsTAP 1447
Cdd:PHA03255   114 TEAGTGTSTgVTSNVTTRSSSTTSATTRITNATTLAPTLSSKGTSNATKTTAELP-TVP 171
zf-H2C2_2 pfam13465
Zinc-finger double domain;
454-479 1.59e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 40.43  E-value: 1.59e-04
                           10        20
                   ....*....|....*....|....*.
gi 1958745358  454 SLKVHIRLHTGVRPFACPHCDKKFRT 479
Cdd:pfam13465    1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-C2H2 pfam00096
Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two ...
 99-121 1.73e-04

Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter.


Pssm-ID: 395048 [Multi-domain]  Cd Length: 23  Bit Score: 39.98  E-value: 1.73e-04
                           10        20
                   ....*....|....*....|...
gi 1958745358   99 YSCPHCGKTFQKPSQLTRHIRIH 121
Cdd:pfam00096    1 YKCPDCGKSFSRKSNLKRHLRTH 23
SUF4-like cd20908
N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), ...
 557-608 1.75e-04

N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana SUF4 (AtSUF4), and similar proteins; Oryza sativa SUPPRESSOR OF FRI 4 (OsSUF4) is a C2H2-type zinc finger transcription factor which interacts with the major H3K36 methyltransferase SDG725 to promote H3K36me3 (tri-methylation at H3K9) establishment. The transcription factor OsSUF4 recognizes a specific 7-bp DNA element (5'-CGGAAAT-3'), which is contained in the promoter regions of many genes throughout the rice genome. Through interaction with OsSUF4, SDG725 is recruited to the promoters of key florigen genes, RICE FLOWERING LOCUS T1 (RFT1) and Heading date 3a (Hd3a), for H3K36 deposition to promote gene activation and rice plant flowering. OsSUF4 target genes include a number of genes involved in many biological processes. Flowering plant Arabidopsis SUF4 binds to a 15bp DNA element (5'-CCAAATTTTAAGTTT-3') within the promoter of the floral repressor gene FLOWERING LOCUS C (FLC) and recruits the FRI-C transcription activator complex to the FLC promoter. Although the DNA-binding element and target genes of AtSUF4 are different from those of OsSUF4, AtSUF4 is known to interact with the Arabidopsis H3K36 methyltransferase SDG8 (also known as ASHH2/EFS/SET8), and the methylation deposition mechanism mediated by the SUF4 transcription factor and H3K36 methyltransferase may be conserved in Arabidopsis and rice. Proteins in this family have two conserved C2H2-type zinc finger motifs at the N-terminus (included in this model), and a large proline-rich domain at the C-terminus; for OsSUF4, it has been shown that the N-terminal zinc-finger domain is responsible for DNA binding, and that the C-terminal domain interacts with SDG725.


Pssm-ID: 411020 [Multi-domain]  Cd Length: 82  Bit Score: 41.77  E-value: 1.75e-04
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1958745358  557 RPYkCFYCHRAYKKSCHLKQHIRSHTgekpFKCSQCGRGFVSAGVLKAHVRT 608
Cdd:cd20908      1 KPW-CYYCDREFDDEKILIQHQKAKH----FKCHICHKKLYTAGGLAVHCLQ 47
zf-H2C2_2 pfam13465
Zinc-finger double domain;
1668-1693 2.33e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 39.66  E-value: 2.33e-04
                           10        20
                   ....*....|....*....|....*.
gi 1958745358 1668 ALQVHMKKHTGERPYRCDYCVMGFTQ 1693
Cdd:pfam13465    1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
zf-H2C2_2 pfam13465
Zinc-finger double domain;
941-966 2.83e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 39.66  E-value: 2.83e-04
                           10        20
                   ....*....|....*....|....*.
gi 1958745358  941 SLTRHMATHMSMKPYKCPFCEEGFRT 966
Cdd:pfam13465    1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
SUF4-like cd20908
N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), ...
 585-634 3.46e-04

N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana SUF4 (AtSUF4), and similar proteins; Oryza sativa SUPPRESSOR OF FRI 4 (OsSUF4) is a C2H2-type zinc finger transcription factor which interacts with the major H3K36 methyltransferase SDG725 to promote H3K36me3 (tri-methylation at H3K9) establishment. The transcription factor OsSUF4 recognizes a specific 7-bp DNA element (5'-CGGAAAT-3'), which is contained in the promoter regions of many genes throughout the rice genome. Through interaction with OsSUF4, SDG725 is recruited to the promoters of key florigen genes, RICE FLOWERING LOCUS T1 (RFT1) and Heading date 3a (Hd3a), for H3K36 deposition to promote gene activation and rice plant flowering. OsSUF4 target genes include a number of genes involved in many biological processes. Flowering plant Arabidopsis SUF4 binds to a 15bp DNA element (5'-CCAAATTTTAAGTTT-3') within the promoter of the floral repressor gene FLOWERING LOCUS C (FLC) and recruits the FRI-C transcription activator complex to the FLC promoter. Although the DNA-binding element and target genes of AtSUF4 are different from those of OsSUF4, AtSUF4 is known to interact with the Arabidopsis H3K36 methyltransferase SDG8 (also known as ASHH2/EFS/SET8), and the methylation deposition mechanism mediated by the SUF4 transcription factor and H3K36 methyltransferase may be conserved in Arabidopsis and rice. Proteins in this family have two conserved C2H2-type zinc finger motifs at the N-terminus (included in this model), and a large proline-rich domain at the C-terminus; for OsSUF4, it has been shown that the N-terminal zinc-finger domain is responsible for DNA binding, and that the C-terminal domain interacts with SDG725.


Pssm-ID: 411020 [Multi-domain]  Cd Length: 82  Bit Score: 41.00  E-value: 3.46e-04
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|
gi 1958745358  585 KPFkCSQCGRGFVSAGVLKAHVRTHTglksFKCLICNGAFTTGGSLRRHM 634
Cdd:cd20908      1 KPW-CYYCDREFDDEKILIQHQKAKH----FKCHICHKKLYTAGGLAVHC 45
zf-H2C2_2 pfam13465
Zinc-finger double domain;
1141-1166 4.45e-04

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 38.89  E-value: 4.45e-04
                           10        20
                   ....*....|....*....|....*.
gi 1958745358 1141 SLKVHMRLHTGAKPFKCPHCELRFRT 1166
Cdd:pfam13465    1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
FhaB COG3210
Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, ...
 1189-1516 5.28e-04

Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 442443 [Multi-domain]  Cd Length: 1698  Bit Score: 45.14  E-value: 5.28e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958745358 1189 VTRSSSENLQSVNLLNSSATDPNVFIMNNSVLTGQFDQNMLQPGLVGQAILPASVSAGGDLTVSLTDGSLATLEGIQLQL 1268
Cdd:COG3210    509 GIATGLTGITAGGGGGGNATSGGTGGDGTTLSGSGLTTTVSGGASGTTAASGSNTANTLGVLAATGGTSNATTAGNSTSA 588

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958745358 1269 AANLVGPNVQISGIDASSINNITLQIDPSILQQTLQQSSLLAQPITGESSTASQNSSLQTSDSTVPASVVIQPISGLSLQ 1348
Cdd:COG3210    589 TGGTGTNSGGTVLSIGTGSAGATGTITLGAGTSGAGANATGGGAGLTGSAVGAALSGTGSGTTGTASANGSNTTGVNTAG 668

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958745358 1349 PTVTSANLTIGPLSEQDSVLTTSNTGTQDLP--------------QVMTSQGLVSTSTGpheITLTINNSSLSQVLAQAA 1414
Cdd:COG3210    669 GTGGGTTGTVTSGATGGTTGTTLNAATGGTLnnagntltistgsiTVTGQIGALANANG---DTVTFGNLGTGATLTLNA 745

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958745358 1415 GPTAssSSGSPQEITLTISE----------LNPSNGSLPSTAPMSPSAISAQNLVMSSSGVGADASVTLTLADTQGmlpg 1484
Cdd:COG3210    746 GVTI--TSGNAGTLSIGLTAnttasgttltLANANGNTSAGATLDNAGAEISIDITADGTITAAGTTAINVTGSGG---- 819

                          330       340       350
                   ....*....|....*....|....*....|..
gi 1958745358 1485 gldTVTLNITSQGQQFPALLTDPSLSGQGGAG 1516
Cdd:COG3210    820 ---TITINTATTGLTGTGDTTSGAGGSNTTDT 848
zf-C2H2 pfam00096
Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two ...
 871-893 7.82e-04

Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter.


Pssm-ID: 395048 [Multi-domain]  Cd Length: 23  Bit Score: 38.44  E-value: 7.82e-04
                           10        20
                   ....*....|....*....|...
gi 1958745358  871 YRCDYCHKGFKKSSHLKQHVRSH 893
Cdd:pfam00096    1 YKCPDCGKSFSRKSNLKRHLRTH 23
SUF4-like cd20908
N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), ...
 101-146 1.42e-03

N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana SUF4 (AtSUF4), and similar proteins; Oryza sativa SUPPRESSOR OF FRI 4 (OsSUF4) is a C2H2-type zinc finger transcription factor which interacts with the major H3K36 methyltransferase SDG725 to promote H3K36me3 (tri-methylation at H3K9) establishment. The transcription factor OsSUF4 recognizes a specific 7-bp DNA element (5'-CGGAAAT-3'), which is contained in the promoter regions of many genes throughout the rice genome. Through interaction with OsSUF4, SDG725 is recruited to the promoters of key florigen genes, RICE FLOWERING LOCUS T1 (RFT1) and Heading date 3a (Hd3a), for H3K36 deposition to promote gene activation and rice plant flowering. OsSUF4 target genes include a number of genes involved in many biological processes. Flowering plant Arabidopsis SUF4 binds to a 15bp DNA element (5'-CCAAATTTTAAGTTT-3') within the promoter of the floral repressor gene FLOWERING LOCUS C (FLC) and recruits the FRI-C transcription activator complex to the FLC promoter. Although the DNA-binding element and target genes of AtSUF4 are different from those of OsSUF4, AtSUF4 is known to interact with the Arabidopsis H3K36 methyltransferase SDG8 (also known as ASHH2/EFS/SET8), and the methylation deposition mechanism mediated by the SUF4 transcription factor and H3K36 methyltransferase may be conserved in Arabidopsis and rice. Proteins in this family have two conserved C2H2-type zinc finger motifs at the N-terminus (included in this model), and a large proline-rich domain at the C-terminus; for OsSUF4, it has been shown that the N-terminal zinc-finger domain is responsible for DNA binding, and that the C-terminal domain interacts with SDG725.


Pssm-ID: 411020 [Multi-domain]  Cd Length: 82  Bit Score: 39.08  E-value: 1.42e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*.
gi 1958745358  101 CPHCGKTFQKPSQLTRHIRIHTgerpFKCSECGKAFNQKGALQTHM 146
Cdd:cd20908      4 CYYCDREFDDEKILIQHQKAKH----FKCHICHKKLYTAGGLAVHC 45
zf-C2H2 pfam00096
Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two ...
 127-149 1.84e-03

Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter.


Pssm-ID: 395048 [Multi-domain]  Cd Length: 23  Bit Score: 37.28  E-value: 1.84e-03
                           10        20
                   ....*....|....*....|...
gi 1958745358  127 FKCSECGKAFNQKGALQTHMIKH 149
Cdd:pfam00096    1 YKCPDCGKSFSRKSNLKRHLRTH 23
SUF4-like cd20908
N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), ...
 1563-1611 1.89e-03

N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana SUF4 (AtSUF4), and similar proteins; Oryza sativa SUPPRESSOR OF FRI 4 (OsSUF4) is a C2H2-type zinc finger transcription factor which interacts with the major H3K36 methyltransferase SDG725 to promote H3K36me3 (tri-methylation at H3K9) establishment. The transcription factor OsSUF4 recognizes a specific 7-bp DNA element (5'-CGGAAAT-3'), which is contained in the promoter regions of many genes throughout the rice genome. Through interaction with OsSUF4, SDG725 is recruited to the promoters of key florigen genes, RICE FLOWERING LOCUS T1 (RFT1) and Heading date 3a (Hd3a), for H3K36 deposition to promote gene activation and rice plant flowering. OsSUF4 target genes include a number of genes involved in many biological processes. Flowering plant Arabidopsis SUF4 binds to a 15bp DNA element (5'-CCAAATTTTAAGTTT-3') within the promoter of the floral repressor gene FLOWERING LOCUS C (FLC) and recruits the FRI-C transcription activator complex to the FLC promoter. Although the DNA-binding element and target genes of AtSUF4 are different from those of OsSUF4, AtSUF4 is known to interact with the Arabidopsis H3K36 methyltransferase SDG8 (also known as ASHH2/EFS/SET8), and the methylation deposition mechanism mediated by the SUF4 transcription factor and H3K36 methyltransferase may be conserved in Arabidopsis and rice. Proteins in this family have two conserved C2H2-type zinc finger motifs at the N-terminus (included in this model), and a large proline-rich domain at the C-terminus; for OsSUF4, it has been shown that the N-terminal zinc-finger domain is responsible for DNA binding, and that the C-terminal domain interacts with SDG725.


Pssm-ID: 411020 [Multi-domain]  Cd Length: 82  Bit Score: 38.69  E-value: 1.89e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*....
gi 1958745358 1563 CLDCDRAFSSAAVLMHHSKEVHGKerihgCRVCRKAFKRATHLKEHMLT 1611
Cdd:cd20908      4 CYYCDREFDDEKILIQHQKAKHFK-----CHICHKKLYTAGGLAVHCLQ 47
zf-C2H2 pfam00096
Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two ...
 384-406 2.30e-03

Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter.


Pssm-ID: 395048 [Multi-domain]  Cd Length: 23  Bit Score: 36.89  E-value: 2.30e-03
                           10        20
                   ....*....|....*....|...
gi 1958745358  384 HVCPYCTKEFRKPSDLVRHIRIH 406
Cdd:pfam00096    1 YKCPDCGKSFSRKSNLKRHLRTH 23
SUF4-like cd20908
N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), ...
 410-458 2.56e-03

N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana SUF4 (AtSUF4), and similar proteins; Oryza sativa SUPPRESSOR OF FRI 4 (OsSUF4) is a C2H2-type zinc finger transcription factor which interacts with the major H3K36 methyltransferase SDG725 to promote H3K36me3 (tri-methylation at H3K9) establishment. The transcription factor OsSUF4 recognizes a specific 7-bp DNA element (5'-CGGAAAT-3'), which is contained in the promoter regions of many genes throughout the rice genome. Through interaction with OsSUF4, SDG725 is recruited to the promoters of key florigen genes, RICE FLOWERING LOCUS T1 (RFT1) and Heading date 3a (Hd3a), for H3K36 deposition to promote gene activation and rice plant flowering. OsSUF4 target genes include a number of genes involved in many biological processes. Flowering plant Arabidopsis SUF4 binds to a 15bp DNA element (5'-CCAAATTTTAAGTTT-3') within the promoter of the floral repressor gene FLOWERING LOCUS C (FLC) and recruits the FRI-C transcription activator complex to the FLC promoter. Although the DNA-binding element and target genes of AtSUF4 are different from those of OsSUF4, AtSUF4 is known to interact with the Arabidopsis H3K36 methyltransferase SDG8 (also known as ASHH2/EFS/SET8), and the methylation deposition mechanism mediated by the SUF4 transcription factor and H3K36 methyltransferase may be conserved in Arabidopsis and rice. Proteins in this family have two conserved C2H2-type zinc finger motifs at the N-terminus (included in this model), and a large proline-rich domain at the C-terminus; for OsSUF4, it has been shown that the N-terminal zinc-finger domain is responsible for DNA binding, and that the C-terminal domain interacts with SDG725.


Pssm-ID: 411020 [Multi-domain]  Cd Length: 82  Bit Score: 38.31  E-value: 2.56e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*....
gi 1958745358  410 KPFkCPQCFRAFAVKSTLTAHIKTHTgikaFKCQYCMKSFSTSGSLKVH 458
Cdd:cd20908      1 KPW-CYYCDREFDDEKILIQHQKAKH----FKCHICHKKLYTAGGLAVH 44
zf-H2C2_2 pfam13465
Zinc-finger double domain;
629-654 3.36e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 36.58  E-value: 3.36e-03
                           10        20
                   ....*....|....*....|....*.
gi 1958745358  629 SLRRHMGIHNDLRPYMCPYCQKTFKT 654
Cdd:pfam13465    1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
SUF4-like cd20908
N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), ...
 1097-1146 3.40e-03

N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana SUF4 (AtSUF4), and similar proteins; Oryza sativa SUPPRESSOR OF FRI 4 (OsSUF4) is a C2H2-type zinc finger transcription factor which interacts with the major H3K36 methyltransferase SDG725 to promote H3K36me3 (tri-methylation at H3K9) establishment. The transcription factor OsSUF4 recognizes a specific 7-bp DNA element (5'-CGGAAAT-3'), which is contained in the promoter regions of many genes throughout the rice genome. Through interaction with OsSUF4, SDG725 is recruited to the promoters of key florigen genes, RICE FLOWERING LOCUS T1 (RFT1) and Heading date 3a (Hd3a), for H3K36 deposition to promote gene activation and rice plant flowering. OsSUF4 target genes include a number of genes involved in many biological processes. Flowering plant Arabidopsis SUF4 binds to a 15bp DNA element (5'-CCAAATTTTAAGTTT-3') within the promoter of the floral repressor gene FLOWERING LOCUS C (FLC) and recruits the FRI-C transcription activator complex to the FLC promoter. Although the DNA-binding element and target genes of AtSUF4 are different from those of OsSUF4, AtSUF4 is known to interact with the Arabidopsis H3K36 methyltransferase SDG8 (also known as ASHH2/EFS/SET8), and the methylation deposition mechanism mediated by the SUF4 transcription factor and H3K36 methyltransferase may be conserved in Arabidopsis and rice. Proteins in this family have two conserved C2H2-type zinc finger motifs at the N-terminus (included in this model), and a large proline-rich domain at the C-terminus; for OsSUF4, it has been shown that the N-terminal zinc-finger domain is responsible for DNA binding, and that the C-terminal domain interacts with SDG725.


Pssm-ID: 411020 [Multi-domain]  Cd Length: 82  Bit Score: 38.31  E-value: 3.40e-03
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|
gi 1958745358 1097 KPYkCDECGKSFTVKSTLDCHVKTHTgqklFSCHVCSNAFSTKGSLKVHM 1146
Cdd:cd20908      1 KPW-CYYCDREFDDEKILIQHQKAKH----FKCHICHKKLYTAGGLAVHC 45
PHA00733 PHA00733
hypothetical protein
 437-487 4.64e-03

hypothetical protein


Pssm-ID: 177301  Cd Length: 128  Bit Score: 39.09  E-value: 4.64e-03
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1958745358  437 IKAFKCQYCMKSFSTSGSLKVHIRL--HTGVrpfaCPHCDKKFRTSGHRKTHV 487
Cdd:PHA00733    71 VSPYVCPLCLMPFSSSVSLKQHIRYteHSKV----CPVCGKEFRNTDSTLDHV 119
zf-H2C2_2 pfam13465
Zinc-finger double domain;
427-451 6.06e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 35.81  E-value: 6.06e-03
                           10        20
                   ....*....|....*....|....*
gi 1958745358  427 LTAHIKTHTGIKAFKCQYCMKSFST 451
Cdd:pfam13465    2 LKRHMRTHTGEKPYKCPECGKSFKS 26
zf-C2H2 pfam00096
Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two ...
 1654-1676 7.32e-03

Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter.


Pssm-ID: 395048 [Multi-domain]  Cd Length: 23  Bit Score: 35.35  E-value: 7.32e-03
                           10        20
                   ....*....|....*....|...
gi 1958745358 1654 FHCTLCEKAFNQKSALQVHMKKH 1676
Cdd:pfam00096    1 YKCPDCGKSFSRKSNLKRHLRTH 23
COG5048 COG5048
FOG: Zn-finger [General function prediction only];
1618-1687 8.14e-03

FOG: Zn-finger [General function prediction only];


Pssm-ID: 227381 [Multi-domain]  Cd Length: 467  Bit Score: 40.83  E-value: 8.14e-03
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1958745358 1618 LSSQKPRVFKCDTCEKAFAKPSQLERHSRIHTGERPFHCTLCEKAFNQK--SALQVHMKKHTGERPYRCDYC 1687
Cdd:COG5048     26 SLSNAPRPDSCPNCTDSFSRLEHLTRHIRSHTGEKPSQCSYSGCDKSFSrpLELSRHLRTHHNNPSDLNSKS 97
zf-C2H2 pfam00096
Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two ...
 1073-1093 8.83e-03

Zinc finger, C2H2 type; The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter.


Pssm-ID: 395048 [Multi-domain]  Cd Length: 23  Bit Score: 35.35  E-value: 8.83e-03
                           10        20
                   ....*....|....*....|.
gi 1958745358 1073 CTYCPKSFKKPSDLVRHVRIH 1093
Cdd:pfam00096    3 CPDCGKSFSRKSNLKRHLRTH 23
ZnF_C2H2 smart00355
zinc finger;
99-121 9.03e-03

zinc finger;


Pssm-ID: 197676  Cd Length: 23  Bit Score: 35.13  E-value: 9.03e-03
                            10        20
                    ....*....|....*....|...
gi 1958745358    99 YSCPHCGKTFQKPSQLTRHIRIH 121
Cdd:smart00355    1 YRCPECGKVFKSKSALREHMRTH 23
SUF4-like cd20908
N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), ...
 873-917 9.23e-03

N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana SUF4 (AtSUF4), and similar proteins; Oryza sativa SUPPRESSOR OF FRI 4 (OsSUF4) is a C2H2-type zinc finger transcription factor which interacts with the major H3K36 methyltransferase SDG725 to promote H3K36me3 (tri-methylation at H3K9) establishment. The transcription factor OsSUF4 recognizes a specific 7-bp DNA element (5'-CGGAAAT-3'), which is contained in the promoter regions of many genes throughout the rice genome. Through interaction with OsSUF4, SDG725 is recruited to the promoters of key florigen genes, RICE FLOWERING LOCUS T1 (RFT1) and Heading date 3a (Hd3a), for H3K36 deposition to promote gene activation and rice plant flowering. OsSUF4 target genes include a number of genes involved in many biological processes. Flowering plant Arabidopsis SUF4 binds to a 15bp DNA element (5'-CCAAATTTTAAGTTT-3') within the promoter of the floral repressor gene FLOWERING LOCUS C (FLC) and recruits the FRI-C transcription activator complex to the FLC promoter. Although the DNA-binding element and target genes of AtSUF4 are different from those of OsSUF4, AtSUF4 is known to interact with the Arabidopsis H3K36 methyltransferase SDG8 (also known as ASHH2/EFS/SET8), and the methylation deposition mechanism mediated by the SUF4 transcription factor and H3K36 methyltransferase may be conserved in Arabidopsis and rice. Proteins in this family have two conserved C2H2-type zinc finger motifs at the N-terminus (included in this model), and a large proline-rich domain at the C-terminus; for OsSUF4, it has been shown that the N-terminal zinc-finger domain is responsible for DNA binding, and that the C-terminal domain interacts with SDG725.


Pssm-ID: 411020 [Multi-domain]  Cd Length: 82  Bit Score: 36.77  E-value: 9.23e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|....*
gi 1958745358  873 CDYCHKGFKKSSHLKQHVRSHTgekpYKCKLCGRGFVSSGVLKSH 917
Cdd:cd20908      4 CYYCDREFDDEKILIQHQKAKH----FKCHICHKKLYTAGGLAVH 44
zf-H2C2_2 pfam13465
Zinc-finger double domain;
398-422 9.43e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 35.42  E-value: 9.43e-03
                           10        20
                   ....*....|....*....|....*
gi 1958745358  398 DLVRHIRIHTHEKPFKCPQCFRAFA 422
Cdd:pfam13465    1 NLKRHMRTHTGEKPYKCPECGKSFK 25
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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