|
Name |
Accession |
Description |
Interval |
E-value |
| PLN02521 |
PLN02521 |
galactokinase |
1-267 |
2.65e-99 |
|
galactokinase
Pssm-ID: 215285 [Multi-domain] Cd Length: 497 Bit Score: 299.32 E-value: 2.65e-99
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958760620 1 MDQSISFLAEEGTAKLIEFSPLRATDVKLPSGAVFVIANSCVEMNKAATSH--FNVRVMECRLAAKVLAKHKGLQWD--- 75
Cdd:PLN02521 209 MDQAISIMAQQGVAKLIDFNPVRATDVQLPAGGTFVIANSLAESNKAVTAAtnYNNRVVECRLAAIVLAVKLGMSAEeai 288
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958760620 76 -KVLRLEEVQSeLGISLEE------MLLVTEDALHAEPYSREEICKCLGISLEELRTQilSPNTQGELT----FKLYQRA 144
Cdd:PLN02521 289 sKVKTLSDVEG-LCVSFAGshgssdPAVAVKELLHEGPYTAEEIEEILGESLTSIFKN--SPTSLAVLKaakhFKLHQRA 365
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958760620 145 KHVYSEAARVLQFKQVCEAAPDNAVQL--LGELMNQSHRSCRDMYECSCPELDQLVDICRKFGAKGSRLTGAGWGGCTVS 222
Cdd:PLN02521 366 VHVYSEAKRVHAFRDTVSSSLSEEEKLkkLGDLMNESHYSCSVLYECSCPELEELVKVCRDNGALGARLTGAGWGGCAVA 445
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|..
gi 1958760620 223 LVPADTLSSFLASVHEAYYQgnmSRLAREKHS-------LFATKPGGGALVF 267
Cdd:PLN02521 446 LVKEAIVPQFILALKEKFYK---SRIEKGVIKeedlglyVFASKPSSGAAIL 494
|
|
| GalK |
COG0153 |
Galactokinase [Carbohydrate transport and metabolism]; |
1-264 |
6.01e-48 |
|
Galactokinase [Carbohydrate transport and metabolism];
Pssm-ID: 439923 [Multi-domain] Cd Length: 380 Bit Score: 163.40 E-value: 6.01e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958760620 1 MDQSISFLAEEGTAKLIEFSPLRATDVKLP-SGAVFVIANSCVEMNkAATSHFNVRVMECRLAAKVLAKhkglqwdKVLR 79
Cdd:COG0153 169 MDQFASALGKKGHALLLDCRSLEYEYVPLPlEGYALVIVDTNVKHS-LADSEYNERRAECEAAAAILGV-------KSLR 240
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958760620 80 leEVqselgiSLEEmllvtedalhaepysreeickclgisLEELRTQILSPntqgeltfKLYQRAKHVYSEAARVLQFkq 159
Cdd:COG0153 241 --DV------TLED--------------------------LEAARARLGDE--------VLRRRARHVVTENQRVLEA-- 276
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958760620 160 vCEAAPDNAVQLLGELMNQSHRSCRDMYECSCPELDQLVDICRKF-GAKGSRLTGAGWGGCTVSLVPADTLSSFLASVHE 238
Cdd:COG0153 277 -VEALRAGDLEAFGKLMNASHASLRDDYEVSCPELDTLVELALAEaGVLGARMTGGGFGGCTIALVPKDAVDEFIEAVAE 355
|
250 260
....*....|....*....|....*.
gi 1958760620 239 AYYQGnmsrlAREKHSLFATKPGGGA 264
Cdd:COG0153 356 AYAEK-----TGLEPDFYVVKPSDGA 376
|
|
| gal_kin |
TIGR00131 |
galactokinase; Galactokinase is a member of the GHMP kinases (Galactokinase, Homoserine kinase, ... |
1-240 |
3.09e-42 |
|
galactokinase; Galactokinase is a member of the GHMP kinases (Galactokinase, Homoserine kinase, Mevalonate kinase, Phosphomevalonate kinase) and shares with them an amino-terminal domain probably related to ATP binding.The galactokinases found by this model are divided into two sets. Prokaryotic forms are generally shorter. The eukaryotic forms are longer because of additional central regions and in some cases are known to be bifunctional, with regulatory activities that are independent of galactokinase activity. [Energy metabolism, Sugars]
Pssm-ID: 272924 [Multi-domain] Cd Length: 386 Bit Score: 148.43 E-value: 3.09e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958760620 1 MDQSISFLAEEGTAKLIEFSPLRATDVKLP-SGAVFVIANSCVEMNkAATSHFNVRVMECRLAAKVLAKHKGLqwdkvlr 79
Cdd:TIGR00131 171 MDQAASVLGKEDHALLVECRSLKATPFKFPqLGIAFVIANTNVKRT-LAPSNYNTRRQECTTAANFLAATDKG------- 242
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958760620 80 leevqselgiSLEEMLLVTEDALHAepysreeickclgisleelRTQILSPNTQgeltfklyQRAKHVYSEAARVLQfkq 159
Cdd:TIGR00131 243 ----------ALRDFMNEYFARYIA-------------------RLTKMLPLVE--------ERAKHVVSENLRVLK--- 282
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958760620 160 VCEAAPDNAVQLLGELMNQSHRSCRDMYECSCPELDQLVDICR-KFGAKGSRLTGAGWGGCTVSLVPADTLSSFLASVHE 238
Cdd:TIGR00131 283 AVKAMKDNDFKQFGALMNESHASCDDDYECTCPEIDELVCSAAlVNGSGGSRMTGAGFGGCTVHLVPNENVDKVRQAVAD 362
|
..
gi 1958760620 239 AY 240
Cdd:TIGR00131 363 KY 364
|
|
| GHMP_kinases_C |
pfam08544 |
GHMP kinases C terminal; This family includes homoserine kinases, galactokinases and ... |
162-242 |
3.61e-09 |
|
GHMP kinases C terminal; This family includes homoserine kinases, galactokinases and mevalonate kinases.
Pssm-ID: 430063 [Multi-domain] Cd Length: 85 Bit Score: 52.47 E-value: 3.61e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958760620 162 EAAPDNAVQLLGELMNQSHRSC--RDMYECSCPELDQLVDICRKFGaKGSRLTGAGWGGCTVSLVP-ADTLSSFLASVHE 238
Cdd:pfam08544 3 EALLRGDLEELGKLLTESAESLepLLVVGILPPELDELLEALLELG-LGAKLSGSGGGPTVFALFKdEDDAEEVARALRE 81
|
....
gi 1958760620 239 AYYQ 242
Cdd:pfam08544 82 AGKK 85
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PLN02521 |
PLN02521 |
galactokinase |
1-267 |
2.65e-99 |
|
galactokinase
Pssm-ID: 215285 [Multi-domain] Cd Length: 497 Bit Score: 299.32 E-value: 2.65e-99
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958760620 1 MDQSISFLAEEGTAKLIEFSPLRATDVKLPSGAVFVIANSCVEMNKAATSH--FNVRVMECRLAAKVLAKHKGLQWD--- 75
Cdd:PLN02521 209 MDQAISIMAQQGVAKLIDFNPVRATDVQLPAGGTFVIANSLAESNKAVTAAtnYNNRVVECRLAAIVLAVKLGMSAEeai 288
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958760620 76 -KVLRLEEVQSeLGISLEE------MLLVTEDALHAEPYSREEICKCLGISLEELRTQilSPNTQGELT----FKLYQRA 144
Cdd:PLN02521 289 sKVKTLSDVEG-LCVSFAGshgssdPAVAVKELLHEGPYTAEEIEEILGESLTSIFKN--SPTSLAVLKaakhFKLHQRA 365
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958760620 145 KHVYSEAARVLQFKQVCEAAPDNAVQL--LGELMNQSHRSCRDMYECSCPELDQLVDICRKFGAKGSRLTGAGWGGCTVS 222
Cdd:PLN02521 366 VHVYSEAKRVHAFRDTVSSSLSEEEKLkkLGDLMNESHYSCSVLYECSCPELEELVKVCRDNGALGARLTGAGWGGCAVA 445
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|..
gi 1958760620 223 LVPADTLSSFLASVHEAYYQgnmSRLAREKHS-------LFATKPGGGALVF 267
Cdd:PLN02521 446 LVKEAIVPQFILALKEKFYK---SRIEKGVIKeedlglyVFASKPSSGAAIL 494
|
|
| GalK |
COG0153 |
Galactokinase [Carbohydrate transport and metabolism]; |
1-264 |
6.01e-48 |
|
Galactokinase [Carbohydrate transport and metabolism];
Pssm-ID: 439923 [Multi-domain] Cd Length: 380 Bit Score: 163.40 E-value: 6.01e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958760620 1 MDQSISFLAEEGTAKLIEFSPLRATDVKLP-SGAVFVIANSCVEMNkAATSHFNVRVMECRLAAKVLAKhkglqwdKVLR 79
Cdd:COG0153 169 MDQFASALGKKGHALLLDCRSLEYEYVPLPlEGYALVIVDTNVKHS-LADSEYNERRAECEAAAAILGV-------KSLR 240
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958760620 80 leEVqselgiSLEEmllvtedalhaepysreeickclgisLEELRTQILSPntqgeltfKLYQRAKHVYSEAARVLQFkq 159
Cdd:COG0153 241 --DV------TLED--------------------------LEAARARLGDE--------VLRRRARHVVTENQRVLEA-- 276
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958760620 160 vCEAAPDNAVQLLGELMNQSHRSCRDMYECSCPELDQLVDICRKF-GAKGSRLTGAGWGGCTVSLVPADTLSSFLASVHE 238
Cdd:COG0153 277 -VEALRAGDLEAFGKLMNASHASLRDDYEVSCPELDTLVELALAEaGVLGARMTGGGFGGCTIALVPKDAVDEFIEAVAE 355
|
250 260
....*....|....*....|....*.
gi 1958760620 239 AYYQGnmsrlAREKHSLFATKPGGGA 264
Cdd:COG0153 356 AYAEK-----TGLEPDFYVVKPSDGA 376
|
|
| gal_kin |
TIGR00131 |
galactokinase; Galactokinase is a member of the GHMP kinases (Galactokinase, Homoserine kinase, ... |
1-240 |
3.09e-42 |
|
galactokinase; Galactokinase is a member of the GHMP kinases (Galactokinase, Homoserine kinase, Mevalonate kinase, Phosphomevalonate kinase) and shares with them an amino-terminal domain probably related to ATP binding.The galactokinases found by this model are divided into two sets. Prokaryotic forms are generally shorter. The eukaryotic forms are longer because of additional central regions and in some cases are known to be bifunctional, with regulatory activities that are independent of galactokinase activity. [Energy metabolism, Sugars]
Pssm-ID: 272924 [Multi-domain] Cd Length: 386 Bit Score: 148.43 E-value: 3.09e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958760620 1 MDQSISFLAEEGTAKLIEFSPLRATDVKLP-SGAVFVIANSCVEMNkAATSHFNVRVMECRLAAKVLAKHKGLqwdkvlr 79
Cdd:TIGR00131 171 MDQAASVLGKEDHALLVECRSLKATPFKFPqLGIAFVIANTNVKRT-LAPSNYNTRRQECTTAANFLAATDKG------- 242
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958760620 80 leevqselgiSLEEMLLVTEDALHAepysreeickclgisleelRTQILSPNTQgeltfklyQRAKHVYSEAARVLQfkq 159
Cdd:TIGR00131 243 ----------ALRDFMNEYFARYIA-------------------RLTKMLPLVE--------ERAKHVVSENLRVLK--- 282
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958760620 160 VCEAAPDNAVQLLGELMNQSHRSCRDMYECSCPELDQLVDICR-KFGAKGSRLTGAGWGGCTVSLVPADTLSSFLASVHE 238
Cdd:TIGR00131 283 AVKAMKDNDFKQFGALMNESHASCDDDYECTCPEIDELVCSAAlVNGSGGSRMTGAGFGGCTVHLVPNENVDKVRQAVAD 362
|
..
gi 1958760620 239 AY 240
Cdd:TIGR00131 363 KY 364
|
|
| PRK05101 |
PRK05101 |
galactokinase; Provisional |
1-242 |
1.41e-27 |
|
galactokinase; Provisional
Pssm-ID: 179937 [Multi-domain] Cd Length: 382 Bit Score: 109.24 E-value: 1.41e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958760620 1 MDQSISFLAEEGTAKLIEFSPLRATDVKLPSGAVFVIANSCVEMNkAATSHFNVRVMECRLAAKVLAKhkglqwdKVLRl 80
Cdd:PRK05101 173 MDQLISALGKKDHALLIDCRSLETKAVPMPEGVAVVIINSNVKRG-LVDSEYNTRRQQCETAARFFGV-------KALR- 243
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958760620 81 eevqselgisleemllvtedalhaepysreeickclGISLEELRTQilspntQGELTFKLYQRAKHVYSEAARVLQFKQV 160
Cdd:PRK05101 244 ------------------------------------DVTLEQFNAV------AAELDPVVAKRARHVITENARTLEAASA 281
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958760620 161 CEAapdNAVQLLGELMNQSHRSCRDMYECSCPELDQLVDICR-KFGAKGS-RLTGAGWGGCTVSLVPADTLSSFLASVHE 238
Cdd:PRK05101 282 LAA---GDLKRMGELMAESHASMRDDFEITVPQIDTLVEIVKaVIGDQGGvRMTGGGFGGCIVALVPEELVEAVRQAVAE 358
|
....
gi 1958760620 239 AYYQ 242
Cdd:PRK05101 359 QYEA 362
|
|
| PRK05322 |
PRK05322 |
galactokinase; Provisional |
18-240 |
4.67e-25 |
|
galactokinase; Provisional
Pssm-ID: 235407 [Multi-domain] Cd Length: 387 Bit Score: 102.24 E-value: 4.67e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958760620 18 EFSPLRATDVKLpsgavfVIANScvemNKA---ATSHFNVRVMECRLAakvlakhkglqwdkvlrLEEVQSELGI-SLEE 93
Cdd:PRK05322 197 EYVPLDLGDYVI------VIMNT----NKRrelADSKYNERRAECEKA-----------------LEELQKKLDIkSLGE 249
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958760620 94 mllVTEDALhaepysreeickclgislEELRTQILSPNtqgeltfkLYQRAKHVYSEAARVLQFKqvcEAAPDNAVQLLG 173
Cdd:PRK05322 250 ---LTEEEF------------------DEYSYLIKDET--------LLKRARHAVTENQRTLKAV---KALKAGDLEKFG 297
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1958760620 174 ELMNQSHRSCRDMYECSCPELDQLVDICRKF-GAKGSRLTGAGWGGCTVSLVPADTLSSFLASVHEAY 240
Cdd:PRK05322 298 RLMNASHVSLRDDYEVTGLELDTLVEAAWKQeGVLGARMTGAGFGGCAIAIVKKDKVEAFKENVGKAY 365
|
|
| PRK03817 |
PRK03817 |
galactokinase; Provisional |
1-241 |
2.96e-23 |
|
galactokinase; Provisional
Pssm-ID: 235163 [Multi-domain] Cd Length: 351 Bit Score: 96.99 E-value: 2.96e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958760620 1 MDQSISFLAEEGTAKLIEFSPLRATDVKLPSGAVFVIANSCVEmNKAATSHFNVRVMECRLAAKVLAKHkglqwdkvlrl 80
Cdd:PRK03817 147 MDQFAVAFGKKDHAIFLDTMTLEYEYVPFPEDYEILVFDTGVK-RELASSEYNERRQECEEALKILGKK----------- 214
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958760620 81 eevqselgiSLEEmllVTEDALHaepysreeickclgiSLEELrtqilspntqgeltfkLYQRAKHVYSEAARVLQFKQv 160
Cdd:PRK03817 215 ---------SSKE---VTEEDLS---------------KLPPL----------------LRKRAGYVLRENERVLKVRD- 250
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958760620 161 ceAAPDNAVQLLGELMNQSHRSCRDMYECSCPELDQLVDICRKFGAKGSRLTGAGWGGCTVSLVPADTLSSFLASVHEAY 240
Cdd:PRK03817 251 --ALKEGDIETLGELLTESHWDLADNYEVSCEELDFFVEFALELGAYGARLTGAGFGGSAIALVDKGKFESIGEELLEEY 328
|
.
gi 1958760620 241 Y 241
Cdd:PRK03817 329 K 329
|
|
| PRK00555 |
PRK00555 |
galactokinase; Provisional |
142-264 |
3.66e-19 |
|
galactokinase; Provisional
Pssm-ID: 179063 [Multi-domain] Cd Length: 363 Bit Score: 85.68 E-value: 3.66e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958760620 142 QRAKHVYSEAARVLQFkqvCEAAPDNAVQLLGELMNQSHRSCRDMYECSCPELDQLVDICRKFGAKGSRLTGAGWGGCTV 221
Cdd:PRK00555 245 RRARHVLTENQRVLDF---AAALADSDFTAAGQLLTASHASMRDDFEITTERIDLIADSAVRAGALGARMTGGGFGGCVI 321
|
90 100 110 120
....*....|....*....|....*....|....*....|...
gi 1958760620 222 SLVPADTLSSFLASVHEAYYQGNMSRlarekHSLFATKPGGGA 264
Cdd:PRK00555 322 ALVPADRAEDVADTVRRAAVTAGYPE-----PAVSRTYAAPGA 359
|
|
| PLN02865 |
PLN02865 |
galactokinase |
1-266 |
3.81e-14 |
|
galactokinase
Pssm-ID: 215466 [Multi-domain] Cd Length: 423 Bit Score: 71.76 E-value: 3.81e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958760620 1 MDQSISFLAEEGTAKLIEFSPLRATDVKLPSGAV-------FVIANSCVEMNKAATSHFNVRVMECRLAAKVLAKHKGLq 73
Cdd:PLN02865 192 LDQSAILLSRYGCLTFMDCKTLDHKLVSLQFQQPggekpfkILLAFSGLRHALTNKPGYNLRVSECQEAARFLLEASGN- 270
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958760620 74 wdkvlrlEEVQSELGisleemllvtedALHAEPYSREeickclgisleelrtqilspntQGELTFKLYQRAKHVYSEAAR 153
Cdd:PLN02865 271 -------DELEPLLC------------NVEPEVYEAH----------------------KCKLEAVLARRAEHYFSENMR 309
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958760620 154 VLQFKqvcEAAPDNAVQLLGELMNQSHRSCRDMYECSCPELDQLVDICRKF-GAKGSRLTGAGWGGCTVSLVPADTLSSF 232
Cdd:PLN02865 310 VIKGV---EAWASGNLEEFGKLISASGLSSIENYECGCEPLIQLYEILLKApGVYGARFSGAGFRGCCVAFVDAEMAEEA 386
|
250 260 270
....*....|....*....|....*....|....*.
gi 1958760620 233 LASVHEAYY--QGNMSRLAREKHSLFATKPGGGALV 266
Cdd:PLN02865 387 ASFVRDEYEkaQPELASNINGDKPVLICEAGDCARV 422
|
|
| PTZ00298 |
PTZ00298 |
mevalonate kinase; Provisional |
139-223 |
4.11e-12 |
|
mevalonate kinase; Provisional
Pssm-ID: 240351 [Multi-domain] Cd Length: 328 Bit Score: 65.26 E-value: 4.11e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958760620 139 KLYQRAKHVYSEAARVLQfkqvceaapDNAVQLLGELMNQSHRSCRDMyECSCPELDQLVDICRKFGAKGSRLTGAGWGG 218
Cdd:PTZ00298 218 RLLENYNACVSEAKEALQ---------KGNLFRVGELMNANHDLCQKL-TVSCRELDSIVQTCRTYGALGAKMSGTGRGG 287
|
....*
gi 1958760620 219 CTVSL 223
Cdd:PTZ00298 288 LVVAL 292
|
|
| PTZ00290 |
PTZ00290 |
galactokinase; Provisional |
1-266 |
9.07e-12 |
|
galactokinase; Provisional
Pssm-ID: 240347 [Multi-domain] Cd Length: 468 Bit Score: 64.46 E-value: 9.07e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958760620 1 MDQSISFLAEEG----------TAKLIEFSPLratdvkLPSGAVFVIANSCV--EMNKAATSHFNVRVMECRLAAKVLAK 68
Cdd:PTZ00290 215 MDQFISAFAEEDkfmfldckslTFESHDMTPL------LGDGACFLLIDSMIkhDLLGGTAGMYNTVRSDQEGAQKKIGK 288
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958760620 69 HKglqwdkvLRLEEVQSELGISLEEMLLVTEDALHAepysreeickclgisLEELRTQIlspnTQGEltfklYQRAKHVY 148
Cdd:PTZ00290 289 HR-------YRGKPFTFSDLVRNPKKYTFDGDVVAF---------------MESCKPLM----TPGE-----FERGTYNI 337
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958760620 149 SEAARVLQFKQVCEAA----PDNAVQLLGELMNQSHRSCRDMYECSCPELDQLVD-ICRKFGAKGSRLTGAGWGGCTVSL 223
Cdd:PTZ00290 338 MEQIRTLEFIKLNDPElplsREERFRKAGEILNAGHQGMRDLMKITTPELDFIHElINEEKGVAGGRMMGGGFGGCIILL 417
|
250 260 270 280
....*....|....*....|....*....|....*....|...
gi 1958760620 224 VPADTLSSFLASVHEAYyqgnMSRLAREkHSLFATKPGGGALV 266
Cdd:PTZ00290 418 LKKNAVDRVVAHVREKF----KARFGVE-NDVYPVVAGDGAFV 455
|
|
| mevalon_kin |
TIGR00549 |
mevalonate kinase; This model represents mevalonate kinase, the third step in the mevalonate ... |
134-223 |
7.36e-11 |
|
mevalonate kinase; This model represents mevalonate kinase, the third step in the mevalonate pathway of isopentanyl pyrophosphate (IPP) biosynthesis. IPP is a common intermediate for a number of pathways including cholesterol biosynthesis. This model covers enzymes from eukaryotes, archaea and bacteria. The related enzyme from the same pathway, phosphmevalonate kinase, serves as an outgroup for this clade. Paracoccus exhibits two genes within the phosphomevalonate/mevalonate kinase family, one of which falls between trusted and noise cutoffs of this model. The degree of divergence is high, but if the trees created from this model are correct, the proper names of these genes have been swapped. [Central intermediary metabolism, Other]
Pssm-ID: 273130 [Multi-domain] Cd Length: 273 Bit Score: 61.15 E-value: 7.36e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958760620 134 GELTFKLYQRAKHVYSEAARVLQfkqvceaapDNAVQLLGELMNQSHrSCRDMYECSCPELDQLVDICRKFGAKGSRLTG 213
Cdd:TIGR00549 194 PELIDSIMDAIGELTLEAKAALQ---------DGDVESLGELMNINQ-GLLKALGVSHPKLDQLVEIARKAGALGAKLTG 263
|
90
....*....|
gi 1958760620 214 AGWGGCTVSL 223
Cdd:TIGR00549 264 AGGGGCMIAL 273
|
|
| ERG12 |
COG1577 |
Mevalonate kinase [Lipid transport and metabolism]; Mevalonate kinase is part of the Pathway ... |
166-224 |
2.23e-10 |
|
Mevalonate kinase [Lipid transport and metabolism]; Mevalonate kinase is part of the Pathway/BioSystem: Isoprenoid biosynthesis
Pssm-ID: 441185 [Multi-domain] Cd Length: 277 Bit Score: 59.47 E-value: 2.23e-10
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 1958760620 166 DNAVQLLGELMNQSHRSCRDMYeCSCPELDQLVDICRKFGAKGSRLTGAGWGGCTVSLV 224
Cdd:COG1577 220 EGDLEALGELMNENHGLLRALG-VSTPELDRLVEAARKAGALGAKLTGAGGGGCVIALA 277
|
|
| GHMP_kinases_C |
pfam08544 |
GHMP kinases C terminal; This family includes homoserine kinases, galactokinases and ... |
162-242 |
3.61e-09 |
|
GHMP kinases C terminal; This family includes homoserine kinases, galactokinases and mevalonate kinases.
Pssm-ID: 430063 [Multi-domain] Cd Length: 85 Bit Score: 52.47 E-value: 3.61e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958760620 162 EAAPDNAVQLLGELMNQSHRSC--RDMYECSCPELDQLVDICRKFGaKGSRLTGAGWGGCTVSLVP-ADTLSSFLASVHE 238
Cdd:pfam08544 3 EALLRGDLEELGKLLTESAESLepLLVVGILPPELDELLEALLELG-LGAKLSGSGGGPTVFALFKdEDDAEEVARALRE 81
|
....
gi 1958760620 239 AYYQ 242
Cdd:pfam08544 82 AGKK 85
|
|
| PRK03926 |
PRK03926 |
mevalonate kinase; Provisional |
172-227 |
9.28e-09 |
|
mevalonate kinase; Provisional
Pssm-ID: 179677 [Multi-domain] Cd Length: 302 Bit Score: 55.06 E-value: 9.28e-09
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 1958760620 172 LGELMNQSHrSCRDMYECSCPELDQLVDICRKFGAKGSRLTGAGWGGCTVSLVPAD 227
Cdd:PRK03926 216 LGELMNINQ-GLLDALGVSTKELSELIYAARTAGALGAKITGAGGGGCMVALAAPE 270
|
|
| COG2605 |
COG2605 |
Predicted kinase related to galactokinase and mevalonate kinase [General function prediction ... |
142-227 |
5.71e-04 |
|
Predicted kinase related to galactokinase and mevalonate kinase [General function prediction only];
Pssm-ID: 442017 [Multi-domain] Cd Length: 328 Bit Score: 40.55 E-value: 5.71e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958760620 142 QRAKHVYSEAARVLQFKQVCEAAPD--NAVQ-----LLGELMNQSHRSCRDMYE-CSCPELDQLVDICRKFGAKGSRLTG 213
Cdd:COG2605 205 QVKNVEDGDEATLEALHEMKELALEmkEALLkgdldEFGELLNEGWELKKRLASgISNPAIDEIYELARKAGALGGKLLG 284
|
90
....*....|....
gi 1958760620 214 AGWGGCTVSLVPAD 227
Cdd:COG2605 285 AGGGGFLLFYAPPE 298
|
|
| |
