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Conserved domains on  [gi|1958645968|ref|XP_038969285|]
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nuclear mitotic apparatus protein 1 isoform X4 [Rattus norvegicus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
HkD_NuMA cd22224
Hook domain found in nuclear mitotic apparatus protein (NuMA) and similar proteins; NuMA, also ...
 6-151 1.16e-50

Hook domain found in nuclear mitotic apparatus protein (NuMA) and similar proteins; NuMA, also called nuclear mitotic apparatus protein 1, or nuclear matrix protein-22 (NMP-22), or SP-H antigen, is a microtubule (MT)-binding protein that plays a role in the formation and maintenance of the spindle poles, and the alignment and segregation of chromosomes during mitotic cell division. The model corresponds to the N-terminal conserved globular Hook domain of NuMA, which folds as a variant of the helical calponin homology (CH) domain. It directly binds dynein light intermediate chains LIC1 and LIC2 through a conserved hydrophobic patch shared among other Hook adaptors.


:

Pssm-ID: 411795  Cd Length: 148  Bit Score: 176.22  E-value: 1.16e-50
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968    6 TRASTLLSWVNSLHVADPVETVLQLQDCSIFIKIINSIHDTKEGQQILQQPLPERLDFVCSFLQKNRKHPSSTQCLVSVQ 85
Cdd:cd22224      2 TKAEALLSWVNSLKLDDPIESISQLQDGTILLKIIYKLKGEEEEEQILDLSVEERLEFISSFLEGDCRFNSSQGTLVSWQ 81

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1958645968   86 KVMEG--SEMELAKMVMLFLYHSTMSSRNPrdWEQFEYGVQAELAVILKFMLDHEDSPNLTEDLENFL 151
Cdd:cd22224     82 KILQGenLELELAKVLLLLLYHSMMNNNLT--LEKLDYKTELELASILRFVLDNEDGLYLSEGLDKFL 147
NuMA_LGNBD cd22298
LGN binding domain (LGNBD) of nuclear mitotic apparatus protein (NuMA) and similar proteins; ...
 1850-1908 1.85e-25

LGN binding domain (LGNBD) of nuclear mitotic apparatus protein (NuMA) and similar proteins; NuMA, also called nuclear matrix protein-22 (NMP-22), nuclear mitotic apparatus protein 1 (NUMA1), or SP-H antigen, is a microtubule (MT)-binding protein that plays a role in the formation and maintenance of spindle poles and the alignment and segregation of chromosomes during mitotic cell division. It is involved in the establishment of mitotic spindle orientation during metaphase, and elongation during anaphase in a dynein-dynactin-dependent manner. NuMA, in complex with LGN, forms NuMA:LGN hetero-hexamers that promote spindle orientation. The model corresponds to the LGN binding domain (LGNBD) of NuMA. LGN (named for leu-gly-asn repeats) is also known as G protein signaling modulator 2.


:

Pssm-ID: 412093  Cd Length: 56  Bit Score: 100.75  E-value: 1.85e-25
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1958645968 1850 LLSLPGYRPTTRSSARRSQtrtSSGAPHGRNSFYMGTCQDEPEQVDDWNRIAELQQRNR 1908
Cdd:cd22298      1 LLSLPGYRPSTRSSTRRSQ---SSSATGGRSTFYMGTCQDEPEHLDDWNRIAELQQRNR 56
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 530-1321 1.99e-23

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 108.99  E-value: 1.99e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  530 LQTLQEQEQAAQGLRQQVEQLssslklkeqqleeaakeqeaaRQDHAQQLATIVEAREASVRERDAARQQLETLEKEKDA 609
Cdd:TIGR02168  202 LKSLERQAEKAERYKELKAEL---------------------RELELALLVLRLEELREELEELQEELKEAEEELEELTA 260

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  610 KLESLQQQLQASNEARDTAQTSVTQAQREKAELSQKIGELHACIEAAHQEQRQAQAHVTELEAQLKAEQQKateREKVVQ 689
Cdd:TIGR02168  261 ELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESK---LDELAE 337

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  690 EKVQLQEQLQALEETLKivrgSLEEEKCRAADALKEQQRHATEMEAETRHLMEQREQEQKELEQEKAERKGLEARLQQLE 769
Cdd:TIGR02168  338 ELAELEEKLEELKEELE----SLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLE 413

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  770 EAH---QAETEALRHELAGATAAQHGAE-SEREQLLREVESWQKRVEARQQEEARYGAMFQEQLMALKGEHGKIGQE--- 842
Cdd:TIGR02168  414 DRRerlQQEIEELLKKLEEAELKELQAElEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARlds 493

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  843 ----EQKEAGEIHGEGQTGQQQSQLAQLHACLAKALQqVQEK---------EARAQKLLDDLSALREKMAATNKEVACLK 909
Cdd:TIGR02168  494 lerlQENLEGFSEGVKALLKNQSGLSGILGVLSELIS-VDEGyeaaieaalGGRLQAVVVENLNAAKKAIAFLKQNELGR 572

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  910 ALVL-----KAGEQQAAASHELKEPPRAGNQESDWEE--EQARPLGS------------TQAALKAVQREAEQM----GG 966
Cdd:TIGR02168  573 VTFLpldsiKGTEIQGNDREILKNIEGFLGVAKDLVKfdPKLRKALSyllggvlvvddlDNALELAKKLRPGYRivtlDG 652

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  967 ELERLRAALMQSQGQQQEVRGQQEREVARLTQERGQAQADLAQekaakaelemrLQNTLNEQRVEFAALQEALTHAMTEK 1046
Cdd:TIGR02168  653 DLVRPGGVITGGSAKTNSSILERRREIEELEEKIEELEEKIAE-----------LEKALAELRKELEELEEELEQLRKEL 721

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1047 EGKDQELAKLREQeaaqiseLKALQQtleelkkkekehptggargedasgdgpgsqlhtpgkteapgpEVEALRAEISKL 1126
Cdd:TIGR02168  722 EELSRQISALRKD-------LARLEA------------------------------------------EVEQLEERIAQL 752

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1127 ERQWQQQQQQVEGLTHSLESERACRAEQDKALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQDHSKAEEEWKAQ 1206
Cdd:TIGR02168  753 SKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERR 832

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1207 VARGQQEAERKSSLISSLEEEVSILNRQVLEKEGESKELKRLVVAESEKSQKLEERLRLL--QVETASSSARAAE-RSSA 1283
Cdd:TIGR02168  833 IAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLrsELEELSEELRELEsKRSE 912

                          810       820       830
                   ....*....|....*....|....*....|....*...
gi 1958645968 1284 LREEVQSLREEVEKQRVVSENLRQELASQAERAEESGQ 1321
Cdd:TIGR02168  913 LRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYS 950
Smc super family cl34174
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1115-1636 2.59e-23

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


The actual alignment was detected with superfamily member COG1196:

Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 108.49  E-value: 2.59e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1115 EVEALRAEISKLERQWQQQQQQVEGLTHSLESERACRAEQDKALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQ 1194
Cdd:COG1196    254 ELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELE 333

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1195 DHSKAEEEWKAQVARGQQEAERKSSLISSLEEEVSILNRQVLEKEGESKELKRLVVAESEKSQKLEERLRLLQVETASSS 1274
Cdd:COG1196    334 ELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALL 413

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1275 ARAAERSSALREEVQSLREEVEKQRVVSENLRQELASQAERAEESGQELKAWQEKFFQKEQALSALQLEHTSTQALVSEL 1354
Cdd:COG1196    414 ERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARL 493

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1355 LPAKHLcqQLQAEQAAAEKRFREEIEQSKQAAGGLQAEL-----MRAQRELGELGSLRQKIVEQERAAQQ----LRAEKA 1425
Cdd:COG1196    494 LLLLEA--EADYEGFLEGVKAALLLAGLRGLAGAVAVLIgveaaYEAALEAALAAALQNIVVEDDEVAAAaieyLKAAKA 571

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1426 SYAE--QLSMLKKAHGLLAEENRGLGERANLGRQFLEVELDQAREKYVQELAAVRTDAETHLAEMRQEAQSTSRELEVMT 1503
Cdd:COG1196    572 GRATflPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTL 651

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1504 AKYESAKVKVLEERQRFQEERQKLTAQVEELNKKLTESEQASRVQQQKLKAFQAQGGESQQEVQCLQTQLSELQAQLSQK 1583
Cdd:COG1196    652 EGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLE 731

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1958645968 1584 EQAAEHYKLQMEKAKTHYDAkkqqNQELREQLQDLEQLQKDNKELRSETERLG 1636
Cdd:COG1196    732 AEREELLEELLEEEELLEEE----ALEELPEPPDLEELERELERLEREIEALG 780
PRK02224 super family cl32023
DNA double-strand break repair Rad50 ATPase;
243-738 1.16e-11

DNA double-strand break repair Rad50 ATPase;


The actual alignment was detected with superfamily member PRK02224:

Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 70.45  E-value: 1.16e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  243 TEKDAQIAMMQQRIDHlALLNEKQAASPQEPSELEEL----------RGKNESLTVRLHETLKQCQNLKTEKNQMDRKIS 312
Cdd:PRK02224   190 DQLKAQIEEKEEKDLH-ERLNGLESELAELDEEIERYeeqreqaretRDEADEVLEEHEERREELETLEAEIEDLRETIA 268

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  313 QLSEENGDLSFKVREFANHLQQLQGAFNDL----------IEEHSKASQEWAEKQAHLESELSTALQDKKCLEEKSEILQ 382
Cdd:PRK02224   269 ETEREREELAEEVRDLRERLEELEEERDDLlaeaglddadAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAESLR 348

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  383 EKISQLEDRAAQLQGSPAPEKGEVLGDALQLDTLKQEAAKLATDNTELQARVETLECERGKQEAQLLAERGHFEEEKRQL 462
Cdd:PRK02224   349 EDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELRERE 428

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  463 ASLVADLQSSVSNLSQAKEELQQ--------------------ASQAQGAQLTAQLASLTALNATLQQQDQELTSLKEQA 522
Cdd:PRK02224   429 AELEATLRTARERVEEAEALLEAgkcpecgqpvegsphvetieEDRERVEELEAELEDLEEEVEEVEERLERAEDLVEAE 508

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  523 K-----KEQAQMLQ--------TLQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQeaarQDHAQQLATIVEAREas 589
Cdd:PRK02224   509 DrierlEERREDLEeliaerreTIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEA----EEAREEVAELNSKLA-- 582

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  590 vrERDAARQQLETLEkEKDAKLESLQQQLQASNEARDTAQTSVTQAQREKAELSQKIGELH-----ACIEAAHQEQRQAQ 664
Cdd:PRK02224   583 --ELKERIESLERIR-TLLAAIADAEDEIERLREKREALAELNDERRERLAEKRERKRELEaefdeARIEEAREDKERAE 659

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1958645968  665 AHVTELEAQLkaeQQKATEREKVVQEKVQLQEQLQALEEtLKIVRGSLeEEKCRAADALKEQQRHATEMEAETR 738
Cdd:PRK02224   660 EYLEQVEEKL---DELREERDDLQAEIGAVENELEELEE-LRERREAL-ENRVEALEALYDEAEELESMYGDLR 728
PHA03307 super family cl33723
transcriptional regulator ICP4; Provisional
 1713-1996 2.08e-03

transcriptional regulator ICP4; Provisional


The actual alignment was detected with superfamily member PHA03307:

Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 43.24  E-value: 2.08e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1713 TPCSVASKLPRTQPDGTSVPGEPASPISQRlPPKVESLESLYFTPIPARGQA--PLETSLDSLGDAFPDSGRKTRSARRR 1790
Cdd:PHA03307   179 PEETARAPSSPPAEPPPSTPPAAASPRPPR-RSSPISASASSPAPAPGRSAAddAGASSSDSSSSESSGCGWGPENECPL 257

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1791 TTQIINITMTKKLELEEPDsaNSSFYSTQSAPASQANLRATSSTQSLARLGSPDDSNSALLSLPGYRP-----TTRSSAR 1865
Cdd:PHA03307   258 PRPAPITLPTRIWEASGWN--GPSSRPGPASSSSSPRERSPSPSPSSPGSGPAPSSPRASSSSSSSREsssssTSSSSES 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1866 RSQTRTSSGAPHGRNsfymGTCQDEPeqvdDWNRIAELQQRNRvcpphlktcypleSRPALSLATITdeemktgDPRETL 1945
Cdd:PHA03307   336 SRGAAVSPGPSPSRS----PSPSRPP----PPADPSSPRKRPR-------------PSRAPSSPAAS-------AGRPTR 387

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1958645968 1946 RRASMQPAQIAEGAGITTRQQRKRVSSETHQGPGTPESKKATscfPRPMTP 1996
Cdd:PHA03307   388 RRARAAVAGRARRRDATGRFPAGRPRPSPLDAGAASGAFYAR---YPLLTP 435
 
Name Accession Description Interval E-value
HkD_NuMA cd22224
Hook domain found in nuclear mitotic apparatus protein (NuMA) and similar proteins; NuMA, also ...
 6-151 1.16e-50

Hook domain found in nuclear mitotic apparatus protein (NuMA) and similar proteins; NuMA, also called nuclear mitotic apparatus protein 1, or nuclear matrix protein-22 (NMP-22), or SP-H antigen, is a microtubule (MT)-binding protein that plays a role in the formation and maintenance of the spindle poles, and the alignment and segregation of chromosomes during mitotic cell division. The model corresponds to the N-terminal conserved globular Hook domain of NuMA, which folds as a variant of the helical calponin homology (CH) domain. It directly binds dynein light intermediate chains LIC1 and LIC2 through a conserved hydrophobic patch shared among other Hook adaptors.


Pssm-ID: 411795  Cd Length: 148  Bit Score: 176.22  E-value: 1.16e-50
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968    6 TRASTLLSWVNSLHVADPVETVLQLQDCSIFIKIINSIHDTKEGQQILQQPLPERLDFVCSFLQKNRKHPSSTQCLVSVQ 85
Cdd:cd22224      2 TKAEALLSWVNSLKLDDPIESISQLQDGTILLKIIYKLKGEEEEEQILDLSVEERLEFISSFLEGDCRFNSSQGTLVSWQ 81

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1958645968   86 KVMEG--SEMELAKMVMLFLYHSTMSSRNPrdWEQFEYGVQAELAVILKFMLDHEDSPNLTEDLENFL 151
Cdd:cd22224     82 KILQGenLELELAKVLLLLLYHSMMNNNLT--LEKLDYKTELELASILRFVLDNEDGLYLSEGLDKFL 147
NuMA_LGNBD cd22298
LGN binding domain (LGNBD) of nuclear mitotic apparatus protein (NuMA) and similar proteins; ...
 1850-1908 1.85e-25

LGN binding domain (LGNBD) of nuclear mitotic apparatus protein (NuMA) and similar proteins; NuMA, also called nuclear matrix protein-22 (NMP-22), nuclear mitotic apparatus protein 1 (NUMA1), or SP-H antigen, is a microtubule (MT)-binding protein that plays a role in the formation and maintenance of spindle poles and the alignment and segregation of chromosomes during mitotic cell division. It is involved in the establishment of mitotic spindle orientation during metaphase, and elongation during anaphase in a dynein-dynactin-dependent manner. NuMA, in complex with LGN, forms NuMA:LGN hetero-hexamers that promote spindle orientation. The model corresponds to the LGN binding domain (LGNBD) of NuMA. LGN (named for leu-gly-asn repeats) is also known as G protein signaling modulator 2.


Pssm-ID: 412093  Cd Length: 56  Bit Score: 100.75  E-value: 1.85e-25
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1958645968 1850 LLSLPGYRPTTRSSARRSQtrtSSGAPHGRNSFYMGTCQDEPEQVDDWNRIAELQQRNR 1908
Cdd:cd22298      1 LLSLPGYRPSTRSSTRRSQ---SSSATGGRSTFYMGTCQDEPEHLDDWNRIAELQQRNR 56
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 530-1321 1.99e-23

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 108.99  E-value: 1.99e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  530 LQTLQEQEQAAQGLRQQVEQLssslklkeqqleeaakeqeaaRQDHAQQLATIVEAREASVRERDAARQQLETLEKEKDA 609
Cdd:TIGR02168  202 LKSLERQAEKAERYKELKAEL---------------------RELELALLVLRLEELREELEELQEELKEAEEELEELTA 260

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  610 KLESLQQQLQASNEARDTAQTSVTQAQREKAELSQKIGELHACIEAAHQEQRQAQAHVTELEAQLKAEQQKateREKVVQ 689
Cdd:TIGR02168  261 ELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESK---LDELAE 337

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  690 EKVQLQEQLQALEETLKivrgSLEEEKCRAADALKEQQRHATEMEAETRHLMEQREQEQKELEQEKAERKGLEARLQQLE 769
Cdd:TIGR02168  338 ELAELEEKLEELKEELE----SLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLE 413

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  770 EAH---QAETEALRHELAGATAAQHGAE-SEREQLLREVESWQKRVEARQQEEARYGAMFQEQLMALKGEHGKIGQE--- 842
Cdd:TIGR02168  414 DRRerlQQEIEELLKKLEEAELKELQAElEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARlds 493

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  843 ----EQKEAGEIHGEGQTGQQQSQLAQLHACLAKALQqVQEK---------EARAQKLLDDLSALREKMAATNKEVACLK 909
Cdd:TIGR02168  494 lerlQENLEGFSEGVKALLKNQSGLSGILGVLSELIS-VDEGyeaaieaalGGRLQAVVVENLNAAKKAIAFLKQNELGR 572

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  910 ALVL-----KAGEQQAAASHELKEPPRAGNQESDWEE--EQARPLGS------------TQAALKAVQREAEQM----GG 966
Cdd:TIGR02168  573 VTFLpldsiKGTEIQGNDREILKNIEGFLGVAKDLVKfdPKLRKALSyllggvlvvddlDNALELAKKLRPGYRivtlDG 652

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  967 ELERLRAALMQSQGQQQEVRGQQEREVARLTQERGQAQADLAQekaakaelemrLQNTLNEQRVEFAALQEALTHAMTEK 1046
Cdd:TIGR02168  653 DLVRPGGVITGGSAKTNSSILERRREIEELEEKIEELEEKIAE-----------LEKALAELRKELEELEEELEQLRKEL 721

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1047 EGKDQELAKLREQeaaqiseLKALQQtleelkkkekehptggargedasgdgpgsqlhtpgkteapgpEVEALRAEISKL 1126
Cdd:TIGR02168  722 EELSRQISALRKD-------LARLEA------------------------------------------EVEQLEERIAQL 752

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1127 ERQWQQQQQQVEGLTHSLESERACRAEQDKALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQDHSKAEEEWKAQ 1206
Cdd:TIGR02168  753 SKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERR 832

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1207 VARGQQEAERKSSLISSLEEEVSILNRQVLEKEGESKELKRLVVAESEKSQKLEERLRLL--QVETASSSARAAE-RSSA 1283
Cdd:TIGR02168  833 IAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLrsELEELSEELRELEsKRSE 912

                          810       820       830
                   ....*....|....*....|....*....|....*...
gi 1958645968 1284 LREEVQSLREEVEKQRVVSENLRQELASQAERAEESGQ 1321
Cdd:TIGR02168  913 LRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYS 950
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1115-1636 2.59e-23

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 108.49  E-value: 2.59e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1115 EVEALRAEISKLERQWQQQQQQVEGLTHSLESERACRAEQDKALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQ 1194
Cdd:COG1196    254 ELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELE 333

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1195 DHSKAEEEWKAQVARGQQEAERKSSLISSLEEEVSILNRQVLEKEGESKELKRLVVAESEKSQKLEERLRLLQVETASSS 1274
Cdd:COG1196    334 ELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALL 413

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1275 ARAAERSSALREEVQSLREEVEKQRVVSENLRQELASQAERAEESGQELKAWQEKFFQKEQALSALQLEHTSTQALVSEL 1354
Cdd:COG1196    414 ERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARL 493

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1355 LPAKHLcqQLQAEQAAAEKRFREEIEQSKQAAGGLQAEL-----MRAQRELGELGSLRQKIVEQERAAQQ----LRAEKA 1425
Cdd:COG1196    494 LLLLEA--EADYEGFLEGVKAALLLAGLRGLAGAVAVLIgveaaYEAALEAALAAALQNIVVEDDEVAAAaieyLKAAKA 571

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1426 SYAE--QLSMLKKAHGLLAEENRGLGERANLGRQFLEVELDQAREKYVQELAAVRTDAETHLAEMRQEAQSTSRELEVMT 1503
Cdd:COG1196    572 GRATflPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTL 651

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1504 AKYESAKVKVLEERQRFQEERQKLTAQVEELNKKLTESEQASRVQQQKLKAFQAQGGESQQEVQCLQTQLSELQAQLSQK 1583
Cdd:COG1196    652 EGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLE 731

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1958645968 1584 EQAAEHYKLQMEKAKTHYDAkkqqNQELREQLQDLEQLQKDNKELRSETERLG 1636
Cdd:COG1196    732 AEREELLEELLEEEELLEEE----ALEELPEPPDLEELERELERLEREIEALG 780
PTZ00121 PTZ00121
MAEBL; Provisional
 589-1345 1.07e-21

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 103.68  E-value: 1.07e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  589 SVRERDAARQQLETLEKEKDAKLESLQQQLQASNEARDTAQTSVTQAQR-----EKAELSQKIGELHACIEAAHQEQRQA 663
Cdd:PTZ00121  1068 QDEGLKPSYKDFDFDAKEDNRADEATEEAFGKAEEAKKTETGKAEEARKaeeakKKAEDARKAEEARKAEDARKAEEARK 1147

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  664 QAHVTELEAQLKAEQQKATEREKVVQEKVQLQEQLQALEetlkiVRGSLEEEKCRAADALKEQQRHATEMEAETRHLMEQ 743
Cdd:PTZ00121  1148 AEDAKRVEIARKAEDARKAEEARKAEDAKKAEAARKAEE-----VRKAEELRKAEDARKAEAARKAEEERKAEEARKAED 1222

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  744 REQEQKELEQEKAERKGLEARLQQLE---EAHQAETEALRHELAGATAAQHGAESEREQLLREVESWQKRVEARQQEEAR 820
Cdd:PTZ00121  1223 AKKAEAVKKAEEAKKDAEEAKKAEEErnnEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKK 1302

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  821 ygamfqeqlmalKGEHGKIGQEEQKEAGEIHGEGQTGQQQSQLAQLHACLAKALQQVQEKEARAQKLLDDLSALREKMAA 900
Cdd:PTZ00121  1303 ------------KADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAE 1370

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  901 TNKEVACLKALVLKAGEQQAAASHELKEPPragnQESDWEEEQARPLGSTQAALKAVQREAEQMGGELERLRAALMQSQG 980
Cdd:PTZ00121  1371 KKKEEAKKKADAAKKKAEEKKKADEAKKKA----EEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKA 1446

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  981 QQQEVRGQQEREVARLTQERGQAQAdlAQEKAAKAElEMRLQNTLNEQRVEFAALQEALTHAMTEKEgKDQELAKLREQE 1060
Cdd:PTZ00121  1447 DEAKKKAEEAKKAEEAKKKAEEAKK--ADEAKKKAE-EAKKADEAKKKAEEAKKKADEAKKAAEAKK-KADEAKKAEEAK 1522

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1061 AAQisELKALQQTLEELKKKEKEHPTggaRGEDASGDGPGSQLHTPGKTEAPGPEVEALRAEISKLERQWQQQQQQVEGL 1140
Cdd:PTZ00121  1523 KAD--EAKKAEEAKKADEAKKAEEKK---KADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEV 1597

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1141 THSLESERACRAEQDKALETLQGQLEEKARELGHNQAASASAQRELQALRaKAQDHSKAEEEWK---AQVARGQQEAERK 1217
Cdd:PTZ00121  1598 MKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKK-KAEELKKAEEENKikaAEEAKKAEEDKKK 1676

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1218 SSLISSLEEEVSILNRQVLEKEGESKELKRLVVAESEKSQKLE-----ERLRLLQVETASssaRAAERSSALREEVQslR 1292
Cdd:PTZ00121  1677 AEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEelkkaEEENKIKAEEAK---KEAEEDKKKAEEAK--K 1751

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1958645968 1293 EEVEKQRVvsenlRQELASQAERAEESGQELKAWQEKFFQKEQALSALQLEHT 1345
Cdd:PTZ00121  1752 DEEEKKKI-----AHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKK 1799
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 412-971 2.84e-21

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 101.94  E-value: 2.84e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  412 QLDTLKQEAAKLATDntELQARVETLECERGKQEAQLLAErghfEEEKRQLASLVADLQSSVSNLSQAKEELQQASQAQG 491
Cdd:COG1196    221 ELKELEAELLLLKLR--ELEAELEELEAELEELEAELEEL----EAELAELEAELEELRLELEELELELEEAQAEEYELL 294

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  492 AQL----------TAQLASLTALNATLQQQDQELTSLKEQAKKEQAQMLQTLQEQEQAAQGLRQQVEQLSSSLKLKEQQL 561
Cdd:COG1196    295 AELarleqdiarlEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAEL 374

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  562 EEAAKEQEAARQDHAQQLATIVEAREAsVRERDAARQQLETLEKEKDAKLESLQQQLQASNEARDTAQTSVTQAQREKAE 641
Cdd:COG1196    375 AEAEEELEELAEELLEALRAAAELAAQ-LEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAE 453

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  642 LSQKIGELHACIEAAHQEQRQAQAHVTELEAQLKAEQQKATEREKVVQEKVQLQEQLQALEETLKIVRGSLEEEKCRAAD 721
Cdd:COG1196    454 LEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVE 533

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  722 ALKEQQRHATEMEAETRHLMEQREQEQKELEQEKAERKGLEARLqQLEEAHQAETEALRHELAGATAAQHGAESEREQLL 801
Cdd:COG1196    534 AAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFL-PLDKIRARAALAAALARGAIGAAVDLVASDLREAD 612

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  802 REVESWQKRVEARQQEEARYGAMFQEQLMALKGEHGKIGQEEQKEAGEIHGEGQTGQQQSQLAQLHACLAKALQQVQEKE 881
Cdd:COG1196    613 ARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEE 692

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  882 ARAQKLLDDLSALREKMAATNKEVACLKALVLKAGEQQAAASHELKEPPRAGNQESDWEEEQARPLGstqAALKAVQREA 961
Cdd:COG1196    693 LELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEP---PDLEELEREL 769

                          570
                   ....*....|
gi 1958645968  962 EQMGGELERL 971
Cdd:COG1196    770 ERLEREIEAL 779
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1003-1679 2.64e-16

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 85.88  E-value: 2.64e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1003 AQADLAQEKAAKAELEMRLqNTLNEQR---VEFAALQEALTHA-----MTEKEGKDQELAKLREQEAAQISELKALQQTL 1074
Cdd:TIGR02168  184 TRENLDRLEDILNELERQL-KSLERQAekaERYKELKAELRELelallVLRLEELREELEELQEELKEAEEELEELTAEL 262

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1075 EELKKKEKEHPTGGARGEDASGDGPGsqlhtpgkteapgpEVEALRAEISKLERQWQQQQQQVEGLTHSLEseracraEQ 1154
Cdd:TIGR02168  263 QELEEKLEELRLEVSELEEEIEELQK--------------ELYALANEISRLEQQKQILRERLANLERQLE-------EL 321

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1155 DKALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQDHSKAEEEWKAQVARGQQEAERKSSLISSLEEEVSILNrq 1234
Cdd:TIGR02168  322 EAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLN-- 399

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1235 vlekegeskelKRLVVAESEKSQKLEERLRLLQVETASSSARAAERSSALREEVQSLREEVEKQRVVSENLRQELASQAE 1314
Cdd:TIGR02168  400 -----------NEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELRE 468

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1315 RAEESGQELKAWQEKFFQKEQ---ALSALQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKrFREEIEQSKQAAGG--L 1389
Cdd:TIGR02168  469 ELEEAEQALDAAERELAQLQArldSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELIS-VDEGYEAAIEAALGgrL 547

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1390 QAELMR------------AQRELG-------------ELGSLRQKIVEQERAAQQLRAEKASYAEQLSM----------- 1433
Cdd:TIGR02168  548 QAVVVEnlnaakkaiaflKQNELGrvtflpldsikgtEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKalsyllggvlv 627

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1434 ---LKKAHGLLAEENRGL-------------------GERANLGRQFLEVELDQAREKY-------------VQELAAVR 1478
Cdd:TIGR02168  628 vddLDNALELAKKLRPGYrivtldgdlvrpggvitggSAKTNSSILERRREIEELEEKIeeleekiaelekaLAELRKEL 707

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1479 TDAETHLAEMRQEAQSTSRELEVMTAKYESAKVKV---LEERQRFQEERQKLTAQVEELNKKLTESEQASRVQQQKLKAF 1555
Cdd:TIGR02168  708 EELEEELEQLRKELEELSRQISALRKDLARLEAEVeqlEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEEL 787

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1556 QAQGGESQQEVQCLQTQLSELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQELREQLQD-----------LEQLQKD 1624
Cdd:TIGR02168  788 EAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEElsedieslaaeIEELEEL 867

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1958645968 1625 NKELRSETERLGRELQQAGLKTKEAEQACRHLTAQVRSLEAQVAHADQQLRDLGK 1679
Cdd:TIGR02168  868 IEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELRE 922
PTZ00121 PTZ00121
MAEBL; Provisional
 959-1650 2.70e-16

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 85.96  E-value: 2.70e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  959 REAEQMGGELERLRAALMQSQGQQQEVRGQQER----EVARLTQERGQAQADLAQEKAAKAELEMRLQNTlneQRVEFAA 1034
Cdd:PTZ00121  1088 RADEATEEAFGKAEEAKKTETGKAEEARKAEEAkkkaEDARKAEEARKAEDARKAEEARKAEDAKRVEIA---RKAEDAR 1164

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1035 LQEALTHAmteKEGKDQELAKlREQEAAQISELKALQQTLEELKKKEKEHPTggaRGEDASGDGPGSQLHTPGKTE-APG 1113
Cdd:PTZ00121  1165 KAEEARKA---EDAKKAEAAR-KAEEVRKAEELRKAEDARKAEAARKAEEER---KAEEARKAEDAKKAEAVKKAEeAKK 1237

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1114 PEVEALRAEisKLERQWQQQQQQVEGLTHSLESERACRAEQDKALETLQGQLEEKARElghnQAASASAQRELQALRAKA 1193
Cdd:PTZ00121  1238 DAEEAKKAE--EERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKAD----EAKKAEEKKKADEAKKKA 1311

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1194 QDHSKAEE--------EWKAQVARGQQEAERKSSLISSLEEEVSILNRQVLEKEGESKELKRlvvaESEKSQKLEERLRL 1265
Cdd:PTZ00121  1312 EEAKKADEakkkaeeaKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKK----EEAKKKADAAKKKA 1387

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1266 LQVETASSSARAAERSSALREEVQslREEVEKQRVVSENLRQELASQAERAEESGQELKAWQEKFFQKEQALSALQLEHT 1345
Cdd:PTZ00121  1388 EEKKKADEAKKKAEEDKKKADELK--KAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKK 1465

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1346 STQALVSELLPAKHLCQQLQAEQAAAEKRFREEIEQSKQAA-GGLQAELMRAQRELGELGSLRQkiVEQERAAQQLR-AE 1423
Cdd:PTZ00121  1466 AEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAeAKKKADEAKKAEEAKKADEAKK--AEEAKKADEAKkAE 1543

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1424 KASYAEQLSM---LKKAHGLL-AEENRGLGERANLGRQFLEvELDQAREKYVQELAAVRTDAETHLAEMRQEAQStsrel 1499
Cdd:PTZ00121  1544 EKKKADELKKaeeLKKAEEKKkAEEAKKAEEDKNMALRKAE-EAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEE----- 1617

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1500 evmtAKYESAKVKVLEERQRFQEERQKltaQVEELNKKLTESEQASrvQQQKLKAFQAQGGESQQevqclQTQLSELQAQ 1579
Cdd:PTZ00121  1618 ----AKIKAEELKKAEEEKKKVEQLKK---KEAEEKKKAEELKKAE--EENKIKAAEEAKKAEED-----KKKAEEAKKA 1683

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1958645968 1580 LSQKEQAAEHYKLQMEKAKTHYDAKKQQNQELREQlqdlEQLQKDNKELRSETERLGRELQQAGLKTKEAE 1650
Cdd:PTZ00121  1684 EEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKA----EELKKAEEENKIKAEEAKKEAEEDKKKAEEAK 1750
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
243-738 1.16e-11

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 70.45  E-value: 1.16e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  243 TEKDAQIAMMQQRIDHlALLNEKQAASPQEPSELEEL----------RGKNESLTVRLHETLKQCQNLKTEKNQMDRKIS 312
Cdd:PRK02224   190 DQLKAQIEEKEEKDLH-ERLNGLESELAELDEEIERYeeqreqaretRDEADEVLEEHEERREELETLEAEIEDLRETIA 268

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  313 QLSEENGDLSFKVREFANHLQQLQGAFNDL----------IEEHSKASQEWAEKQAHLESELSTALQDKKCLEEKSEILQ 382
Cdd:PRK02224   269 ETEREREELAEEVRDLRERLEELEEERDDLlaeaglddadAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAESLR 348

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  383 EKISQLEDRAAQLQGSPAPEKGEVLGDALQLDTLKQEAAKLATDNTELQARVETLECERGKQEAQLLAERGHFEEEKRQL 462
Cdd:PRK02224   349 EDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELRERE 428

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  463 ASLVADLQSSVSNLSQAKEELQQ--------------------ASQAQGAQLTAQLASLTALNATLQQQDQELTSLKEQA 522
Cdd:PRK02224   429 AELEATLRTARERVEEAEALLEAgkcpecgqpvegsphvetieEDRERVEELEAELEDLEEEVEEVEERLERAEDLVEAE 508

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  523 K-----KEQAQMLQ--------TLQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQeaarQDHAQQLATIVEAREas 589
Cdd:PRK02224   509 DrierlEERREDLEeliaerreTIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEA----EEAREEVAELNSKLA-- 582

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  590 vrERDAARQQLETLEkEKDAKLESLQQQLQASNEARDTAQTSVTQAQREKAELSQKIGELH-----ACIEAAHQEQRQAQ 664
Cdd:PRK02224   583 --ELKERIESLERIR-TLLAAIADAEDEIERLREKREALAELNDERRERLAEKRERKRELEaefdeARIEEAREDKERAE 659

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1958645968  665 AHVTELEAQLkaeQQKATEREKVVQEKVQLQEQLQALEEtLKIVRGSLeEEKCRAADALKEQQRHATEMEAETR 738
Cdd:PRK02224   660 EYLEQVEEKL---DELREERDDLQAEIGAVENELEELEE-LRERREAL-ENRVEALEALYDEAEELESMYGDLR 728
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 304-879 5.90e-10

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 64.75  E-value: 5.90e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  304 KNQMDRKISQLSeengDLSFKVREFANHLQQLQGAFNDLIEEhskasqewAEKQAHL-ESELSTALQDKKCLEEKS---- 378
Cdd:pfam15921  309 RNQNSMYMRQLS----DLESTVSQLRSELREAKRMYEDKIEE--------LEKQLVLaNSELTEARTERDQFSQESgnld 376

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  379 EILQEKISQLEDRAAQLQGSPAPEK---GEVLGDALQLDTLKQEAAKLATDNTELQARVETLECE-RGKQEAQLLAERGH 454
Cdd:pfam15921  377 DQLQKLLADLHKREKELSLEKEQNKrlwDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSEcQGQMERQMAAIQGK 456

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  455 fEEEKRQLASLVADLQSSVSNLSQAKEELqqasqaqgaqltaqlaslTALNATLQQQDQELTSLKeqakkeqaqmlQTLQ 534
Cdd:pfam15921  457 -NESLEKVSSLTAQLESTKEMLRKVVEEL------------------TAKKMTLESSERTVSDLT-----------ASLQ 506

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  535 EQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEqeaarQDHAQQLATiveareasvrERDAARQQLetleKEKDAKLESL 614
Cdd:pfam15921  507 EKERAIEATNAEITKLRSRVDLKLQELQHLKNE-----GDHLRNVQT----------ECEALKLQM----AEKDKVIEIL 567

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  615 QQQLQASNEARDTAQTSVTQAQREKAELSQKIG-------ELHACIEAAHQEQRQAQAHVTELEAQLKAEQQKATEREKV 687
Cdd:pfam15921  568 RQQIENMTQLVGQHGRTAGAMQVEKAQLEKEINdrrlelqEFKILKDKKDAKIRELEARVSDLELEKVKLVNAGSERLRA 647

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  688 VQEKVQLQEQLQALEETLKIVRGSLEEEkcraADALKEQQRHAT-EMEAETRHLmeqreqeqkeleqeKAERKGLEARLQ 766
Cdd:pfam15921  648 VKDIKQERDQLLNEVKTSRNELNSLSED----YEVLKRNFRNKSeEMETTTNKL--------------KMQLKSAQSELE 709

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  767 QLEEAHQAETEALRHELAGATAAQHGAESEREQlLREVESWQKRVEARQQEEARYGAMFQEQLMALKGEHGKIGQEEQKE 846
Cdd:pfam15921  710 QTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQ-IDALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKM 788

                          570       580       590
                   ....*....|....*....|....*....|....
gi 1958645968  847 AGEIHG-EGQTGQQQSQLAQLHACLAKALQQVQE 879
Cdd:pfam15921  789 AGELEVlRSQERRLKEKVANMEVALDKASLQFAE 822
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 354-703 3.29e-08

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 59.20  E-value: 3.29e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  354 AEKQAHLESelstALQDKKCLEEKSEILQEKISQLEDRAAQLQGSPAPEKGevLGDALQLD----TLKQEAAKLATDNTE 429
Cdd:COG3096    278 NERRELSER----ALELRRELFGARRQLAEEQYRLVEMARELEELSARESD--LEQDYQAAsdhlNLVQTALRQQEKIER 351

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  430 LQARVETLE----------CERGKQEAQLLAERGHFEEEKRQLASLVADLQSSVSNLS----------QAKEELQQASQA 489
Cdd:COG3096    352 YQEDLEELTerleeqeevvEEAAEQLAEAEARLEAAEEEVDSLKSQLADYQQALDVQQtraiqyqqavQALEKARALCGL 431

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  490 QGAQLTAQLASLTALNATLQQQDQELTSLKEQ------AKKEQAQMLQTLQ------EQEQAAQGLRQQVEQLSSsLKLK 557
Cdd:COG3096    432 PDLTPENAEDYLAAFRAKEQQATEEVLELEQKlsvadaARRQFEKAYELVCkiagevERSQAWQTARELLRRYRS-QQAL 510

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  558 EQQLEEAAKEQEAARQDHAQQLATIVEAREASVR--ERDAARQQLETLEKEKDAKLESLQQQLQASNEARDTAQTSVTQA 635
Cdd:COG3096    511 AQRLQQLRAQLAELEQRLRQQQNAERLLEEFCQRigQQLDAAEELEELLAELEAQLEELEEQAAEAVEQRSELRQQLEQL 590

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1958645968  636 QREKAELSQKIGELHACIEAAHQEQRQAQAHVTELEAQLKAEQQKATEREKVVQEKVQLQEQLQALEE 703
Cdd:COG3096    591 RARIKELAARAPAWLAAQDALERLREQSGEALADSQEVTAAMQQLLEREREATVERDELAARKQALES 658
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 1152-1650 1.20e-07

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 57.04  E-value: 1.20e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1152 AEQDKALETLQGQLEEKARELGHNQAASASAQREL--QALRAKAQDHSKAEEEWKaQVARGQQEAERKsslISSLEEEVS 1229
Cdd:pfam05483  168 AEKTKKYEYEREETRQVYMDLNNNIEKMILAFEELrvQAENARLEMHFKLKEDHE-KIQHLEEEYKKE---INDKEKQVS 243

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1230 ILNRQVLEKEGESKELKRLVVAESEKSQKLEERLRLLQVETASSSARAAERSSALREEVQSLREEVEKQRVVSENLRQEL 1309
Cdd:pfam05483  244 LLLIQITEKENKMKDLTFLLEESRDKANQLEEKTKLQDENLKELIEKKDHLTKELEDIKMSLQRSMSTQKALEEDLQIAT 323

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1310 ASQAERAEESgqelKAWQEKFFQKEQALSALQLEHTSTQALVSELLPAKhlcqqlqaeqaaaekrfREEIEQSKQAAGGL 1389
Cdd:pfam05483  324 KTICQLTEEK----EAQMEELNKAKAAHSFVVTEFEATTCSLEELLRTE-----------------QQRLEKNEDQLKII 382

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1390 QAELMRAQRELGELGSLRQKIVEQERAAQQLRAEKasyaEQLSMLKKAHGLLAEENRGLGERAnlgrqfleVELDQAREK 1469
Cdd:pfam05483  383 TMELQKKSSELEEMTKFKNNKEVELEELKKILAED----EKLLDEKKQFEKIAEELKGKEQEL--------IFLLQAREK 450

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1470 YVQELaavrtdaETHLAEMRQEAQSTSRELEVMTAKYESAKVKVLE----------ERQRFQEERQKLTAQVEELNKKLT 1539
Cdd:pfam05483  451 EIHDL-------EIQLTAIKTSEEHYLKEVEDLKTELEKEKLKNIEltahcdklllENKELTQEASDMTLELKKHQEDII 523

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1540 ESEQASRVQQQKLKAFQAQGGESQQEVQCLQTQL----SELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQELREQL 1615
Cdd:pfam05483  524 NCKKQEERMLKQIENLEEKEMNLRDELESVREEFiqkgDEVKCKLDKSEENARSIEYEVLKKEKQMKILENKCNNLKKQI 603

                          490       500       510
                   ....*....|....*....|....*....|....*....
gi 1958645968 1616 QD----LEQLQKDNKELRSETERLGRELQQAGLKTKEAE 1650
Cdd:pfam05483  604 ENknknIEELHQENKALKKKGSAENKQLNAYEIKVNKLE 642
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 214-483 1.08e-06

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 54.30  E-value: 1.08e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  214 MRRLKKQLADERNNRDELELELSESLKLLTEKDAQIAMMQQRidhlalLNEKQAASPQEpseLEELRGKNESLTVRLHET 293
Cdd:TIGR02169  686 LKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQ------LEQEEEKLKER---LEELEEDLSSLEQEIENV 756

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  294 LKQCQNLKTEKNQMDRKISQLSEENGDLsfKVREFANHLQQLQGAFNDLIEEHSkasqEWAEKQAHLESELSTALQDKKC 373
Cdd:TIGR02169  757 KSELKELEARIEELEEDLHKLEEALNDL--EARLSHSRIPEIQAELSKLEEEVS----RIEARLREIEQKLNRLTLEKEY 830

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  374 LEEKSEILQEKISQLEDRAAQLQGspapekgevlgdalQLDTLKQEAAKLATDNTELQARVETLECERGKQEAQLLAERG 453
Cdd:TIGR02169  831 LEKEIQELQEQRIDLKEQIKSIEK--------------EIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEA 896

                          250       260       270
                   ....*....|....*....|....*....|
gi 1958645968  454 HFEEEKRQLASLVADLQSSVSNLSQAKEEL 483
Cdd:TIGR02169  897 QLRELERKIEELEAQIEKKRKRLSELKAKL 926
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 252-774 7.18e-06

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 51.33  E-value: 7.18e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  252 MQQRIDHLALLNEKQAASPQEPSELEELRGKNESLTVRLHETLKQCQNLKTEKNQMDRKIS----QLSEENGDLSFKVRE 327
Cdd:pfam01576    7 MQAKEEELQKVKERQQKAESELKELEKKHQQLCEEKNALQEQLQAETELCAEAEEMRARLAarkqELEEILHELESRLEE 86

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  328 FANHLQQLQGafndlieEHSKASQEWAEKQAHLESELST--ALQ-DKKCLEEKSEILQEKISQLEDRAAQLQGSPAPEKG 404
Cdd:pfam01576   87 EEERSQQLQN-------EKKKMQQHIQDLEEQLDEEEAArqKLQlEKVTTEAKIKKLEEDILLLEDQNSKLSKERKLLEE 159

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  405 EVLGDALQLDTLKQEAAKLATDNTELQARVETLECERGKQEAQllaeRGHFEEEKRQLASLVADLQSSVSNLSQAKEELQ 484
Cdd:pfam01576  160 RISEFTSNLAEEEEKAKSLSKLKNKHEAMISDLEERLKKEEKG----RQELEKAKRKLEGESTDLQEQIAELQAQIAELR 235

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  485 QASQAQGAQLTAQLASL---TALNATLQQQDQELTS----LKEQAKKEQAQM--------------------LQTLQEQE 537
Cdd:pfam01576  236 AQLAKKEEELQAALARLeeeTAQKNNALKKIRELEAqiseLQEDLESERAARnkaekqrrdlgeelealkteLEDTLDTT 315

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  538 QAAQGLRQQVEQLSSSLKLK-EQQLEEAAKEQEAARQDHAQQLATIVEAREASVRER---DAARQQLETLEKEKDAKLES 613
Cdd:pfam01576  316 AAQQELRSKREQEVTELKKAlEEETRSHEAQLQEMRQKHTQALEELTEQLEQAKRNKanlEKAKQALESENAELQAELRT 395

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  614 LQQQLQASNEARDTA-------QTSVTQAQREKAELSQKIGELHACIEAAHQEQRQAQAHVTELEAQLKAEQQKATEREK 686
Cdd:pfam01576  396 LQQAKQDSEHKRKKLegqlqelQARLSESERQRAELAEKLSKLQSELESVSSLLNEAEGKNIKLSKDVSSLESQLQDTQE 475

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  687 VVQE----KVQLQEQLQALEETLKIVRGSLEEEKCRAADALKEQQRHATEMEAETRHLMEQREQEQKELEQEKAERKGLE 762
Cdd:pfam01576  476 LLQEetrqKLNLSTRLRQLEDERNSLQEQLEEEEEAKRNVERQLSTLQAQLSDMKKKLEEDAGTLEALEEGKKRLQRELE 555

                          570
                   ....*....|..
gi 1958645968  763 ARLQQLEEAHQA 774
Cdd:pfam01576  556 ALTQQLEEKAAA 567
HpsJ_fam NF038305
HpsJ family protein; HpsJ (hormogornium polysaccharide J) is thought to be involved in the ...
 504-619 4.30e-04

HpsJ family protein; HpsJ (hormogornium polysaccharide J) is thought to be involved in the biosynthesis or secretion of an extracellular polysaccharide shared by many Cyanobacteria.


Pssm-ID: 468465 [Multi-domain]  Cd Length: 230  Bit Score: 44.11  E-value: 4.30e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  504 LNATLQQQDQELTSLKEQAKKEQAQmLQTLQEQEQAAQGlRQQVEQLSSSLKLKEQQLEEAAKEqeaarQDHAQQLATIV 583
Cdd:NF038305    99 LNNTRRLSTQALQQINQQAGQQETQ-LQQQLNQLQAQTS-PQQLNQLLKSEQKQGQALASGQLP-----EEQKEQLQQFK 171

                           90       100       110
                   ....*....|....*....|....*....|....*...
gi 1958645968  584 EAREASVRERDAARQQLET--LEKEKDAKLESLQQQLQ 619
Cdd:NF038305   172 SNPQALDKFLAQQLTQIRTqaEEAEKQARLEALKSSLR 209
MARTX_Nterm NF012221
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...
 341-648 1.07e-03

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.


Pssm-ID: 467957 [Multi-domain]  Cd Length: 1848  Bit Score: 44.44  E-value: 1.07e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  341 DLIEEHSKASQEWAEKQAHLESELST--ALQDKKCLEEKSEIL-QEKISQLEDRA---AQLQgSPAPEKGEVLGDAlQLD 414
Cdd:NF012221  1532 DNVVATSESSQQADAVSKHAKQDDAAqnALADKERAEADRQRLeQEKQQQLAAISgsqSQLE-STDQNALETNGQA-QRD 1609

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  415 TLKQEAAKLATDNTELQARVETLEcergkQEAQLLAERGhfEEEKRQLA-SLVADLQSSVSNlsqakeelqqasqaqgaq 493
Cdd:NF012221  1610 AILEESRAVTKELTTLAQGLDALD-----SQATYAGESG--DQWRNPFAgGLLDRVQEQLDD------------------ 1664

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  494 ltAQLASLTALNATLQQQDQELTSLKEQAKKEQAQMLQTLQEQEQAAQGLRQQveqlssslklkeqqleeaakeqeaarq 573
Cdd:NF012221  1665 --AKKISGKQLADAKQRHVDNQQKVKDAVAKSEAGVAQGEQNQANAEQDIDDA--------------------------- 1715

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1958645968  574 dhaqqlativeAREASVRERDAARQQLETLEKEKDAKLESLQQQLQASNEARdTAQTSVTQAQREKAELSQKIGE 648
Cdd:NF012221  1716 -----------KADAEKRKDDALAKQNEAQQAESDANAAANDAQSRGEQDAS-AAENKANQAQADAKGAKQDESD 1778
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 1713-1996 2.08e-03

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 43.24  E-value: 2.08e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1713 TPCSVASKLPRTQPDGTSVPGEPASPISQRlPPKVESLESLYFTPIPARGQA--PLETSLDSLGDAFPDSGRKTRSARRR 1790
Cdd:PHA03307   179 PEETARAPSSPPAEPPPSTPPAAASPRPPR-RSSPISASASSPAPAPGRSAAddAGASSSDSSSSESSGCGWGPENECPL 257

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1791 TTQIINITMTKKLELEEPDsaNSSFYSTQSAPASQANLRATSSTQSLARLGSPDDSNSALLSLPGYRP-----TTRSSAR 1865
Cdd:PHA03307   258 PRPAPITLPTRIWEASGWN--GPSSRPGPASSSSSPRERSPSPSPSSPGSGPAPSSPRASSSSSSSREsssssTSSSSES 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1866 RSQTRTSSGAPHGRNsfymGTCQDEPeqvdDWNRIAELQQRNRvcpphlktcypleSRPALSLATITdeemktgDPRETL 1945
Cdd:PHA03307   336 SRGAAVSPGPSPSRS----PSPSRPP----PPADPSSPRKRPR-------------PSRAPSSPAAS-------AGRPTR 387

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1958645968 1946 RRASMQPAQIAEGAGITTRQQRKRVSSETHQGPGTPESKKATscfPRPMTP 1996
Cdd:PHA03307   388 RRARAAVAGRARRRDATGRFPAGRPRPSPLDAGAASGAFYAR---YPLLTP 435
TOPEUc smart00435
DNA Topoisomerase I (eukaryota); DNA Topoisomerase I (eukaryota), DNA topoisomerase V, Vaccina ...
 1593-1676 4.91e-03

DNA Topoisomerase I (eukaryota); DNA Topoisomerase I (eukaryota), DNA topoisomerase V, Vaccina virus topoisomerase, Variola virus topoisomerase, Shope fibroma virus topoisomeras


Pssm-ID: 214661 [Multi-domain]  Cd Length: 391  Bit Score: 41.57  E-value: 4.91e-03
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  1593 QMEKAKTHYDAKKQQNQELREQLQDLEQLQKDNKELRSETERLGRELQQAGLKTKEAEQACRHLTAQVRSLEAQVAHADQ 1672
Cdd:smart00435  278 SMEKLQEKIKALKYQLKRLKKMILLFEMISDLKRKLKSKFERDNEKLDAEVKEKKKEKKKEEKKKKQIERLEERIEKLEV 357


                    ....
gi 1958645968  1673 QLRD 1676
Cdd:smart00435  358 QATD 361
 
Name Accession Description Interval E-value
HkD_NuMA cd22224
Hook domain found in nuclear mitotic apparatus protein (NuMA) and similar proteins; NuMA, also ...
 6-151 1.16e-50

Hook domain found in nuclear mitotic apparatus protein (NuMA) and similar proteins; NuMA, also called nuclear mitotic apparatus protein 1, or nuclear matrix protein-22 (NMP-22), or SP-H antigen, is a microtubule (MT)-binding protein that plays a role in the formation and maintenance of the spindle poles, and the alignment and segregation of chromosomes during mitotic cell division. The model corresponds to the N-terminal conserved globular Hook domain of NuMA, which folds as a variant of the helical calponin homology (CH) domain. It directly binds dynein light intermediate chains LIC1 and LIC2 through a conserved hydrophobic patch shared among other Hook adaptors.


Pssm-ID: 411795  Cd Length: 148  Bit Score: 176.22  E-value: 1.16e-50
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968    6 TRASTLLSWVNSLHVADPVETVLQLQDCSIFIKIINSIHDTKEGQQILQQPLPERLDFVCSFLQKNRKHPSSTQCLVSVQ 85
Cdd:cd22224      2 TKAEALLSWVNSLKLDDPIESISQLQDGTILLKIIYKLKGEEEEEQILDLSVEERLEFISSFLEGDCRFNSSQGTLVSWQ 81

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1958645968   86 KVMEG--SEMELAKMVMLFLYHSTMSSRNPrdWEQFEYGVQAELAVILKFMLDHEDSPNLTEDLENFL 151
Cdd:cd22224     82 KILQGenLELELAKVLLLLLYHSMMNNNLT--LEKLDYKTELELASILRFVLDNEDGLYLSEGLDKFL 147
NuMA_LGNBD cd22298
LGN binding domain (LGNBD) of nuclear mitotic apparatus protein (NuMA) and similar proteins; ...
 1850-1908 1.85e-25

LGN binding domain (LGNBD) of nuclear mitotic apparatus protein (NuMA) and similar proteins; NuMA, also called nuclear matrix protein-22 (NMP-22), nuclear mitotic apparatus protein 1 (NUMA1), or SP-H antigen, is a microtubule (MT)-binding protein that plays a role in the formation and maintenance of spindle poles and the alignment and segregation of chromosomes during mitotic cell division. It is involved in the establishment of mitotic spindle orientation during metaphase, and elongation during anaphase in a dynein-dynactin-dependent manner. NuMA, in complex with LGN, forms NuMA:LGN hetero-hexamers that promote spindle orientation. The model corresponds to the LGN binding domain (LGNBD) of NuMA. LGN (named for leu-gly-asn repeats) is also known as G protein signaling modulator 2.


Pssm-ID: 412093  Cd Length: 56  Bit Score: 100.75  E-value: 1.85e-25
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 1958645968 1850 LLSLPGYRPTTRSSARRSQtrtSSGAPHGRNSFYMGTCQDEPEQVDDWNRIAELQQRNR 1908
Cdd:cd22298      1 LLSLPGYRPSTRSSTRRSQ---SSSATGGRSTFYMGTCQDEPEHLDDWNRIAELQQRNR 56
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 530-1321 1.99e-23

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 108.99  E-value: 1.99e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  530 LQTLQEQEQAAQGLRQQVEQLssslklkeqqleeaakeqeaaRQDHAQQLATIVEAREASVRERDAARQQLETLEKEKDA 609
Cdd:TIGR02168  202 LKSLERQAEKAERYKELKAEL---------------------RELELALLVLRLEELREELEELQEELKEAEEELEELTA 260

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  610 KLESLQQQLQASNEARDTAQTSVTQAQREKAELSQKIGELHACIEAAHQEQRQAQAHVTELEAQLKAEQQKateREKVVQ 689
Cdd:TIGR02168  261 ELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESK---LDELAE 337

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  690 EKVQLQEQLQALEETLKivrgSLEEEKCRAADALKEQQRHATEMEAETRHLMEQREQEQKELEQEKAERKGLEARLQQLE 769
Cdd:TIGR02168  338 ELAELEEKLEELKEELE----SLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLE 413

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  770 EAH---QAETEALRHELAGATAAQHGAE-SEREQLLREVESWQKRVEARQQEEARYGAMFQEQLMALKGEHGKIGQE--- 842
Cdd:TIGR02168  414 DRRerlQQEIEELLKKLEEAELKELQAElEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARlds 493

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  843 ----EQKEAGEIHGEGQTGQQQSQLAQLHACLAKALQqVQEK---------EARAQKLLDDLSALREKMAATNKEVACLK 909
Cdd:TIGR02168  494 lerlQENLEGFSEGVKALLKNQSGLSGILGVLSELIS-VDEGyeaaieaalGGRLQAVVVENLNAAKKAIAFLKQNELGR 572

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  910 ALVL-----KAGEQQAAASHELKEPPRAGNQESDWEE--EQARPLGS------------TQAALKAVQREAEQM----GG 966
Cdd:TIGR02168  573 VTFLpldsiKGTEIQGNDREILKNIEGFLGVAKDLVKfdPKLRKALSyllggvlvvddlDNALELAKKLRPGYRivtlDG 652

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  967 ELERLRAALMQSQGQQQEVRGQQEREVARLTQERGQAQADLAQekaakaelemrLQNTLNEQRVEFAALQEALTHAMTEK 1046
Cdd:TIGR02168  653 DLVRPGGVITGGSAKTNSSILERRREIEELEEKIEELEEKIAE-----------LEKALAELRKELEELEEELEQLRKEL 721

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1047 EGKDQELAKLREQeaaqiseLKALQQtleelkkkekehptggargedasgdgpgsqlhtpgkteapgpEVEALRAEISKL 1126
Cdd:TIGR02168  722 EELSRQISALRKD-------LARLEA------------------------------------------EVEQLEERIAQL 752

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1127 ERQWQQQQQQVEGLTHSLESERACRAEQDKALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQDHSKAEEEWKAQ 1206
Cdd:TIGR02168  753 SKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERR 832

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1207 VARGQQEAERKSSLISSLEEEVSILNRQVLEKEGESKELKRLVVAESEKSQKLEERLRLL--QVETASSSARAAE-RSSA 1283
Cdd:TIGR02168  833 IAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLrsELEELSEELRELEsKRSE 912

                          810       820       830
                   ....*....|....*....|....*....|....*...
gi 1958645968 1284 LREEVQSLREEVEKQRVVSENLRQELASQAERAEESGQ 1321
Cdd:TIGR02168  913 LRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYS 950
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1115-1636 2.59e-23

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 108.49  E-value: 2.59e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1115 EVEALRAEISKLERQWQQQQQQVEGLTHSLESERACRAEQDKALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQ 1194
Cdd:COG1196    254 ELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELE 333

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1195 DHSKAEEEWKAQVARGQQEAERKSSLISSLEEEVSILNRQVLEKEGESKELKRLVVAESEKSQKLEERLRLLQVETASSS 1274
Cdd:COG1196    334 ELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALL 413

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1275 ARAAERSSALREEVQSLREEVEKQRVVSENLRQELASQAERAEESGQELKAWQEKFFQKEQALSALQLEHTSTQALVSEL 1354
Cdd:COG1196    414 ERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARL 493

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1355 LPAKHLcqQLQAEQAAAEKRFREEIEQSKQAAGGLQAEL-----MRAQRELGELGSLRQKIVEQERAAQQ----LRAEKA 1425
Cdd:COG1196    494 LLLLEA--EADYEGFLEGVKAALLLAGLRGLAGAVAVLIgveaaYEAALEAALAAALQNIVVEDDEVAAAaieyLKAAKA 571

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1426 SYAE--QLSMLKKAHGLLAEENRGLGERANLGRQFLEVELDQAREKYVQELAAVRTDAETHLAEMRQEAQSTSRELEVMT 1503
Cdd:COG1196    572 GRATflPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTL 651

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1504 AKYESAKVKVLEERQRFQEERQKLTAQVEELNKKLTESEQASRVQQQKLKAFQAQGGESQQEVQCLQTQLSELQAQLSQK 1583
Cdd:COG1196    652 EGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLE 731

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1958645968 1584 EQAAEHYKLQMEKAKTHYDAkkqqNQELREQLQDLEQLQKDNKELRSETERLG 1636
Cdd:COG1196    732 AEREELLEELLEEEELLEEE----ALEELPEPPDLEELERELERLEREIEALG 780
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 300-1070 6.79e-23

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 107.45  E-value: 6.79e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  300 LKTEKNQMDRKISQLSEENGDLSFKVREFANHLQQLQGAfndlIEEHSKASQEWAEKQAHLESELSTALQDKKCLEEKSE 379
Cdd:TIGR02168  230 LVLRLEELREELEELQEELKEAEEELEELTAELQELEEK----LEELRLEVSELEEEIEELQKELYALANEISRLEQQKQ 305

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  380 ILQEKISQLEDRAAQLQGSPAPEKGEVLGDALQLDTLKQEAAKLATDNTELQARVETLECERGKQEAQLLAERGHFEEEK 459
Cdd:TIGR02168  306 ILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLR 385

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  460 RQLASLVADLQSSVSNLSQAKEELQQASQAQGAQLTAQLASLTALNATLQQQDQELTSLKEQAKKEQAQMLQTLQEQEQA 539
Cdd:TIGR02168  386 SKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEE 465

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  540 AQGLRQQVEQLSSSLKLKEQQLEEAAKEQEAARQDH---AQQLATIVEAREASVRERDAARQQLETLEKEKDAKLESLQQ 616
Cdd:TIGR02168  466 LREELEEAEQALDAAERELAQLQARLDSLERLQENLegfSEGVKALLKNQSGLSGILGVLSELISVDEGYEAAIEAALGG 545

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  617 QLQA----SNEARDTAQTSVTQAQREKAELSQKIGELHACIEAAHQEQRQAQAHVTELEAQL---KAEQQKATE----RE 685
Cdd:TIGR02168  546 RLQAvvveNLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLvkfDPKLRKALSyllgGV 625

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  686 KVVQEKVQLQEQLQALEETLKIVrgSLEEEKCRA------ADALKEQQRhaTEMEAETRHLMEQREQEQKELEQEKAERK 759
Cdd:TIGR02168  626 LVVDDLDNALELAKKLRPGYRIV--TLDGDLVRPggvitgGSAKTNSSI--LERRREIEELEEKIEELEEKIAELEKALA 701

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  760 GLEARLQQLEEahqaETEALRHELAGATAAQHGAESEREQLLREVESWQKRVEARQQEEARYGAMFQEQLMALKGEHGKI 839
Cdd:TIGR02168  702 ELRKELEELEE----ELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEEL 777

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  840 GQEEQKEAGEihgEGQTGQQQSQLAQLHACLAKALQQVQEKEARAQKLLDDLSALREKMAATNKEVACLKALVLKAGEQQ 919
Cdd:TIGR02168  778 AEAEAEIEEL---EAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDI 854

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  920 AAASHELkeppragnqesdweEEQARPLGSTQAALKAVQREAEQMGGELERLRAALMQSQGQQQEVrgqqEREVARLTQE 999
Cdd:TIGR02168  855 ESLAAEI--------------EELEELIEELESELEALLNERASLEEALALLRSELEELSEELREL----ESKRSELRRE 916

                          730       740       750       760       770       780       790
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1958645968 1000 RGQAQADLAQEKAAKAELEMRLQNTLNEQRVEFAALQEaltHAMTEKEGKDQELAKLREQEAAQISELKAL 1070
Cdd:TIGR02168  917 LEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLE---EAEALENKIEDDEEEARRRLKRLENKIKEL 984
PTZ00121 PTZ00121
MAEBL; Provisional
 589-1345 1.07e-21

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 103.68  E-value: 1.07e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  589 SVRERDAARQQLETLEKEKDAKLESLQQQLQASNEARDTAQTSVTQAQR-----EKAELSQKIGELHACIEAAHQEQRQA 663
Cdd:PTZ00121  1068 QDEGLKPSYKDFDFDAKEDNRADEATEEAFGKAEEAKKTETGKAEEARKaeeakKKAEDARKAEEARKAEDARKAEEARK 1147

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  664 QAHVTELEAQLKAEQQKATEREKVVQEKVQLQEQLQALEetlkiVRGSLEEEKCRAADALKEQQRHATEMEAETRHLMEQ 743
Cdd:PTZ00121  1148 AEDAKRVEIARKAEDARKAEEARKAEDAKKAEAARKAEE-----VRKAEELRKAEDARKAEAARKAEEERKAEEARKAED 1222

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  744 REQEQKELEQEKAERKGLEARLQQLE---EAHQAETEALRHELAGATAAQHGAESEREQLLREVESWQKRVEARQQEEAR 820
Cdd:PTZ00121  1223 AKKAEAVKKAEEAKKDAEEAKKAEEErnnEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKK 1302

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  821 ygamfqeqlmalKGEHGKIGQEEQKEAGEIHGEGQTGQQQSQLAQLHACLAKALQQVQEKEARAQKLLDDLSALREKMAA 900
Cdd:PTZ00121  1303 ------------KADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAE 1370

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  901 TNKEVACLKALVLKAGEQQAAASHELKEPPragnQESDWEEEQARPLGSTQAALKAVQREAEQMGGELERLRAALMQSQG 980
Cdd:PTZ00121  1371 KKKEEAKKKADAAKKKAEEKKKADEAKKKA----EEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKA 1446

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  981 QQQEVRGQQEREVARLTQERGQAQAdlAQEKAAKAElEMRLQNTLNEQRVEFAALQEALTHAMTEKEgKDQELAKLREQE 1060
Cdd:PTZ00121  1447 DEAKKKAEEAKKAEEAKKKAEEAKK--ADEAKKKAE-EAKKADEAKKKAEEAKKKADEAKKAAEAKK-KADEAKKAEEAK 1522

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1061 AAQisELKALQQTLEELKKKEKEHPTggaRGEDASGDGPGSQLHTPGKTEAPGPEVEALRAEISKLERQWQQQQQQVEGL 1140
Cdd:PTZ00121  1523 KAD--EAKKAEEAKKADEAKKAEEKK---KADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEV 1597

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1141 THSLESERACRAEQDKALETLQGQLEEKARELGHNQAASASAQRELQALRaKAQDHSKAEEEWK---AQVARGQQEAERK 1217
Cdd:PTZ00121  1598 MKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKK-KAEELKKAEEENKikaAEEAKKAEEDKKK 1676

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1218 SSLISSLEEEVSILNRQVLEKEGESKELKRLVVAESEKSQKLE-----ERLRLLQVETASssaRAAERSSALREEVQslR 1292
Cdd:PTZ00121  1677 AEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEelkkaEEENKIKAEEAK---KEAEEDKKKAEEAK--K 1751

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1958645968 1293 EEVEKQRVvsenlRQELASQAERAEESGQELKAWQEKFFQKEQALSALQLEHT 1345
Cdd:PTZ00121  1752 DEEEKKKI-----AHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKK 1799
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 412-971 2.84e-21

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 101.94  E-value: 2.84e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  412 QLDTLKQEAAKLATDntELQARVETLECERGKQEAQLLAErghfEEEKRQLASLVADLQSSVSNLSQAKEELQQASQAQG 491
Cdd:COG1196    221 ELKELEAELLLLKLR--ELEAELEELEAELEELEAELEEL----EAELAELEAELEELRLELEELELELEEAQAEEYELL 294

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  492 AQL----------TAQLASLTALNATLQQQDQELTSLKEQAKKEQAQMLQTLQEQEQAAQGLRQQVEQLSSSLKLKEQQL 561
Cdd:COG1196    295 AELarleqdiarlEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAEL 374

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  562 EEAAKEQEAARQDHAQQLATIVEAREAsVRERDAARQQLETLEKEKDAKLESLQQQLQASNEARDTAQTSVTQAQREKAE 641
Cdd:COG1196    375 AEAEEELEELAEELLEALRAAAELAAQ-LEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAE 453

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  642 LSQKIGELHACIEAAHQEQRQAQAHVTELEAQLKAEQQKATEREKVVQEKVQLQEQLQALEETLKIVRGSLEEEKCRAAD 721
Cdd:COG1196    454 LEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVE 533

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  722 ALKEQQRHATEMEAETRHLMEQREQEQKELEQEKAERKGLEARLqQLEEAHQAETEALRHELAGATAAQHGAESEREQLL 801
Cdd:COG1196    534 AAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFL-PLDKIRARAALAAALARGAIGAAVDLVASDLREAD 612

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  802 REVESWQKRVEARQQEEARYGAMFQEQLMALKGEHGKIGQEEQKEAGEIHGEGQTGQQQSQLAQLHACLAKALQQVQEKE 881
Cdd:COG1196    613 ARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEE 692

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  882 ARAQKLLDDLSALREKMAATNKEVACLKALVLKAGEQQAAASHELKEPPRAGNQESDWEEEQARPLGstqAALKAVQREA 961
Cdd:COG1196    693 LELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEP---PDLEELEREL 769

                          570
                   ....*....|
gi 1958645968  962 EQMGGELERL 971
Cdd:COG1196    770 ERLEREIEAL 779
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 330-905 3.34e-21

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 101.55  E-value: 3.34e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  330 NHLQQLQGAFNDLIEEHSKASQEWAEKQAHLESELSTALQDKKCLEEKSEILQEKISQLEDRAAQLQGSPAPEKGEVLGD 409
Cdd:COG1196    235 RELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRREL 314

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  410 ALQLDTLKQEAAKLATDNTELQARVETLEcergKQEAQLLAERGHFEEEKRQLASLVADLQSSVSNLSQAKEELQQASQA 489
Cdd:COG1196    315 EERLEELEEELAELEEELEELEEELEELE----EELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLE 390

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  490 QGAQLTAQLASLTALNATLQQQDQELTSLKEQAKKEQAQMLQTLQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQE 569
Cdd:COG1196    391 ALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLE 470

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  570 AARQDHAQQLATIVEAREASVRERDAARQQLETLEKEKDAKLESLQQQLQ---------ASNEARDTAQTSVTQAQREKA 640
Cdd:COG1196    471 EAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRglagavavlIGVEAAYEAALEAALAAALQN 550

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  641 ELSQKIGELHACIEAAHQEQRQAQAHVTELEAQLKAEQQKATEREKVVQEKVQLQEQLQALEETLKIVRGSLEEEKCRAA 720
Cdd:COG1196    551 IVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAA 630

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  721 DALKEQQRHAT--EMEAETRHLMEQREQEQKELEQEKAERKGLEARLQQLEEAHQAETEALRHELAGATAAQHGAESERE 798
Cdd:COG1196    631 RLEAALRRAVTlaGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELA 710

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  799 QLLREVESWQKRVEARQQEEARYGAMFQEQLMALKGEhgkigqEEQKEAGEIHGEGQTGQQQSQLAQLHACLAK------ 872
Cdd:COG1196    711 EAEEERLEEELEEEALEEQLEAEREELLEELLEEEEL------LEEEALEELPEPPDLEELERELERLEREIEAlgpvnl 784

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|.
gi 1958645968  873 -ALQQVQEKEARAQKL---LDDLSA----LREKMAATNKEV 905
Cdd:COG1196    785 lAIEEYEELEERYDFLseqREDLEEaretLEEAIEEIDRET 825
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 761-1620 6.89e-21

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 100.90  E-value: 6.89e-21
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  761 LEARLQQLE-EAHQAE-----TEALRH-ELAGATAAQHGAESEREQLLREVESWQKRVEARQQEEARYgamfQEQLMALK 833
Cdd:TIGR02168  198 LERQLKSLErQAEKAErykelKAELRElELALLVLRLEELREELEELQEELKEAEEELEELTAELQEL----EEKLEELR 273

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  834 GEHGKIGQEEQKEAGEIHG--------EGQTGQQQSQLAQLHACLAKALQQVQEKEARAQKLLDDLSALREKMAATNKEV 905
Cdd:TIGR02168  274 LEVSELEEEIEELQKELYAlaneisrlEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEEL 353

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  906 ACLKALVLKAGEQQAAAShelkeppragNQESDWEEEqarpLGSTQAALKAVQREAEQMGGELERLRAALMQSqgqqqev 985
Cdd:TIGR02168  354 ESLEAELEELEAELEELE----------SRLEELEEQ----LETLRSKVAQLELQIASLNNEIERLEARLERL------- 412

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  986 rgqqEREVARLTQERGQAQADLaqEKAAKAELEMRL---QNTLNEQRVEFAALQEALTHAMTEKEGKDQELAKLREQEAA 1062
Cdd:TIGR02168  413 ----EDRRERLQQEIEELLKKL--EEAELKELQAELeelEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQ 486

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1063 QISELKALQQTLEELKKKEKEHPTGGARGEDASGDGP--GSQLHTPGKTEApgpEVE-ALRAEISKLerqwqqqqqqveg 1139
Cdd:TIGR02168  487 LQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGvlSELISVDEGYEA---AIEaALGGRLQAV------------- 550

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1140 LTHSLESERACRAEQDKALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQDHSKAEEEWKA-------------- 1205
Cdd:TIGR02168  551 VVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKalsyllggvlvvdd 630

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1206 -QVARGQQEAERKSSLISSLEEEVsILNRQVLEKEGESKELKRLvvAESEKSQKLEERLRLLQVETASSSARAAErssaL 1284
Cdd:TIGR02168  631 lDNALELAKKLRPGYRIVTLDGDL-VRPGGVITGGSAKTNSSIL--ERRREIEELEEKIEELEEKIAELEKALAE----L 703

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1285 REEVQSLREEVEKQRVVSENLRQELASQAERAEESGQELKAWQEKFFQKEQALSALQLEHTSTQALVSELLPAKHLCQQL 1364
Cdd:TIGR02168  704 RKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAE 783

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1365 QAEQAAAEKRFREEIEQSKQAAGGLQAELMRaqrelgelgsLRQKIVEQERAAQQLRAEKASYAEQLSMLKKAHGLLAEE 1444
Cdd:TIGR02168  784 IEELEAQIEQLKEELKALREALDELRAELTL----------LNEEAANLRERLESLERRIAATERRLEDLEEQIEELSED 853

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1445 nrglgeranlgrqfleveldqarekyVQELAAVRTDAETHLAEMRQEAQSTSRELEVMTakyesakvkvlEERQRFQEER 1524
Cdd:TIGR02168  854 --------------------------IESLAAEIEELEELIEELESELEALLNERASLE-----------EALALLRSEL 896

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1525 QKLTAQVEELNKKLTESEQASRVQQQKLKAFQAQGGESQQEVQclqtqlselqaqlSQKEQAAEHYKLQMEKAKTHYDAK 1604
Cdd:TIGR02168  897 EELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRID-------------NLQERLSEEYSLTLEEAEALENKI 963

                          890
                   ....*....|....*.
gi 1958645968 1605 KQQNQELREQLQDLEQ 1620
Cdd:TIGR02168  964 EDDEEEARRRLKRLEN 979
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 207-945 9.25e-20

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 97.05  E-value: 9.25e-20
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  207 LQTPQFQMRRLKKQLADERNNRDELELELSESLKLLTEKDAQIAMMQQRI-DHLALLNEKQAASPQEPSELEELRGKNES 285
Cdd:TIGR02168  241 LEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELyALANEISRLEQQKQILRERLANLERQLEE 320

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  286 LTVRLHETLKQCQNLKTEKNQMDRKISQLSEENGDLSFKVREFANHLQQLQGAFNDLIEEHSKASQEWAE---KQAHLES 362
Cdd:TIGR02168  321 LEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQlelQIASLNN 400

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  363 ELSTALQDKKCLEEKSEILQEKISQLEDRaaqlqgspaPEKGEVLGDALQLDTLKQEAAKLATDNTELQARVETLECERG 442
Cdd:TIGR02168  401 EIERLEARLERLEDRRERLQQEIEELLKK---------LEEAELKELQAELEELEEELEELQEELERLEEALEELREELE 471

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  443 KQEAQLLAERGHFEEEKRQLASLVaDLQSSVSNLSQAKEELQQASQaqgaqltaQLASLTALNATLQQQDQELTSLKEQA 522
Cdd:TIGR02168  472 EAEQALDAAERELAQLQARLDSLE-RLQENLEGFSEGVKALLKNQS--------GLSGILGVLSELISVDEGYEAAIEAA 542

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  523 KKEQAQML--QTLQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEAARQDHAQQLATIVEAREASVRERDAARQQL 600
Cdd:TIGR02168  543 LGGRLQAVvvENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLL 622

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  601 ETLekekdAKLESLQQQLQASNEARD------------TAQTSVTQAQREKA----ELSQKIGELHACIEAAHQEQRQAQ 664
Cdd:TIGR02168  623 GGV-----LVVDDLDNALELAKKLRPgyrivtldgdlvRPGGVITGGSAKTNssilERRREIEELEEKIEELEEKIAELE 697

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  665 AHVTELEAQLkaeQQKATEREKVVQEKVQLQEQLQALEETLKIvrgsLEEEKCRAADALKEQQRHATEMEAETRHLMEQR 744
Cdd:TIGR02168  698 KALAELRKEL---EELEEELEQLRKELEELSRQISALRKDLAR----LEAEVEQLEERIAQLSKELTELEAEIEELEERL 770

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  745 EQEQKELEQEKAERKGLEARLQQLEEAHQAETE---ALRHELAGATAAQHGAESEREQLLREVESWQKRVEARQQEEARy 821
Cdd:TIGR02168  771 EEAEEELAEAEAEIEELEAQIEQLKEELKALREaldELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEE- 849

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  822 gamFQEQLMALKGEHGKIGQEEQKEAGEI-HGEGQTGQQQSQLAQLHACLAKALQQVQEKEARAQKLLDDLSALREKMAA 900
Cdd:TIGR02168  850 ---LSEDIESLAAEIEELEELIEELESELeALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQ 926

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|
gi 1958645968  901 TNKEVACLKALVLK-----AGEQQAAASHELKEPPRAGNQESDWEEEQAR 945
Cdd:TIGR02168  927 LELRLEGLEVRIDNlqerlSEEYSLTLEEAEALENKIEDDEEEARRRLKR 976
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 591-1419 1.45e-19

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 96.28  E-value: 1.45e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  591 RERDAARQQLETLEKEKDAKLESLQQQLQASNEARDTAQTSVTQAQREKAELSQKIGELHACIEAAHQEQRQAQAHVTEL 670
Cdd:TIGR02168  207 RQAEKAERYKELKAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEEL 286

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  671 EAQLkaeQQKATEREKVVQEKVQLQEQLQALEETLKIVRGSLEEEKCRaadaLKEQQRHATEMEAETRHLMEQREQEQKE 750
Cdd:TIGR02168  287 QKEL---YALANEISRLEQQKQILRERLANLERQLEELEAQLEELESK----LDELAEELAELEEKLEELKEELESLEAE 359

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  751 LEQEKAERKGLEARLQQLEEAHqaetEALRHELAGATAAQHGAESEREQLLREVESWQKRVEARQQEEARYGAMFQEQlm 830
Cdd:TIGR02168  360 LEELEAELEELESRLEELEEQL----ETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEA-- 433

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  831 ALKGEHGKIGQEEQKEAGEIHGEGQTGQQQSQLAQLHACLAKALQQVQEKEARAQKLLDDLSALREKMAATNKEVACLKA 910
Cdd:TIGR02168  434 ELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLK 513

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  911 LVLKAGEQQAAASHELkeppragNQESDWEeeqarplgstqAALKAVQREaeqmggeleRLRAALMQSQgqqqevrgqqe 990
Cdd:TIGR02168  514 NQSGLSGILGVLSELI-------SVDEGYE-----------AAIEAALGG---------RLQAVVVENL----------- 555

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  991 rEVARLTQErgqAQADLAQEKAAKAELEMRLQNTLNEQRVEFAALQEALTHAMTEKEGKDQELAKLREQEAAQISELKAL 1070
Cdd:TIGR02168  556 -NAAKKAIA---FLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDL 631

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1071 QQTLEELKKKEKEHPTGGARGEDASGDGPGSqlhtpGKTEAPGPEVEALRAEISKLERQWQQQQQQVeglthsleserac 1150
Cdd:TIGR02168  632 DNALELAKKLRPGYRIVTLDGDLVRPGGVIT-----GGSAKTNSSILERRREIEELEEKIEELEEKI------------- 693

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1151 rAEQDKALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQDHSKAEEEWKAQVARGQQEAERKSSLISSLEEEVSI 1230
Cdd:TIGR02168  694 -AELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEE 772

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1231 LNRQVLEKEGESKELKRLV-------VAESEKSQKLEERLRLLQVETASSSARAAE---RSSALREEVQSLREEVEKQRV 1300
Cdd:TIGR02168  773 AEEELAEAEAEIEELEAQIeqlkeelKALREALDELRAELTLLNEEAANLRERLESlerRIAATERRLEDLEEQIEELSE 852

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1301 VSENLRQELASQAERAEESGQELKAWQEKFFQKEQALSALQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKRFREEIE 1380
Cdd:TIGR02168  853 DIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLE 932

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|
gi 1958645968 1381 QSKQAAGGLQAELM-RAQRELGELGSLRQKIVEQERAAQQ 1419
Cdd:TIGR02168  933 GLEVRIDNLQERLSeEYSLTLEEAEALENKIEDDEEEARR 972
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 213-884 2.23e-19

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 95.89  E-value: 2.23e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  213 QMRRLKKQLADERNNRDELELELSESLKLLTEKDAQIAMMQQRIDHL-----ALLNEKQAASPQE---PSELEELRGKNE 284
Cdd:TIGR02168  240 ELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELqkelyALANEISRLEQQKqilRERLANLERQLE 319

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  285 SLTVRLHETLKQCQNLKTEKNQMDRKISQLSEENGDLSFKVREFANHLQQLQGAFNDLIEEHSKASQEWAE---KQAHLE 361
Cdd:TIGR02168  320 ELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQlelQIASLN 399

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  362 SELSTALQDKKCLEEKSEILQEKISQLEDRaaqlqgspaPEKGEVLGDALQLDTLKQEAAKLATDNTELQARVETLECER 441
Cdd:TIGR02168  400 NEIERLEARLERLEDRRERLQQEIEELLKK---------LEEAELKELQAELEELEEELEELQEELERLEEALEELREEL 470

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  442 GKQEAQLLAERGHFEEEKRQLASLVADLQS------SVSNLSQAKEELQQASQAQGAQLTA----QLASLTALNATLQQ- 510
Cdd:TIGR02168  471 EEAEQALDAAERELAQLQARLDSLERLQENlegfseGVKALLKNQSGLSGILGVLSELISVdegyEAAIEAALGGRLQAv 550

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  511 -------------------------------QDQELTSLKEQAKKEQAQMLQTLQEQEQAAQGLRQQVEQLSSSLKLKEq 559
Cdd:TIGR02168  551 vvenlnaakkaiaflkqnelgrvtflpldsiKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVD- 629

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  560 qlEEAAKEQEAARQDHAQQLATI--------------VEAREASVRERDAARQQLETLEKEKDAKLESLQQQLQASNEAR 625
Cdd:TIGR02168  630 --DLDNALELAKKLRPGYRIVTLdgdlvrpggvitggSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKEL 707

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  626 DTAQTSVTQAQREKAELSQKIGELHACIEAAHQEQRQAQAHVTELEAQLKAEQQKATEREkvvQEKVQLQEQLQALEEtl 705
Cdd:TIGR02168  708 EELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELE---ERLEEAEEELAEAEA-- 782

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  706 kiVRGSLEEEKCRAADALKEQQRHATEMEAETRHLMEQREQEQKELEQEKAERKGLEARLQQLEEahqaETEALRHELAG 785
Cdd:TIGR02168  783 --EIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEE----QIEELSEDIES 856

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  786 ATAAQHGAESEREQLLREVESWQKRVEARqqeearygamfQEQLMALKGEHGKIGQEEQKEAGEIHG-EGQTGQQQSQLA 864
Cdd:TIGR02168  857 LAAEIEELEELIEELESELEALLNERASL-----------EEALALLRSELEELSEELRELESKRSElRRELEELREKLA 925

                          730       740
                   ....*....|....*....|
gi 1958645968  865 QLHACLAKALQQVQEKEARA 884
Cdd:TIGR02168  926 QLELRLEGLEVRIDNLQERL 945
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 274-823 3.35e-19

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 95.00  E-value: 3.35e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  274 SELEELRGknESLTVRLHETLKQCQNLKTEKNQMDRKISQLSEENGDLSFKVREFANHLQQLQGAFNDLIEEHSKASQEW 353
Cdd:COG1196    220 EELKELEA--ELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAEL 297

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  354 AEKQAHLESELSTALQDKKCLEEKSEILQEKISQLEDRAAQLQGspapEKGEVLGDALQLDTLKQEAAKLATDNTELQAR 433
Cdd:COG1196    298 ARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEE----LEEELEEAEEELEEAEAELAEAEEALLEAEAE 373

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  434 VETLECERGKQEAQLLAERGHFEEEKRQLASLVADLQSSVSNLSQAKEELQQASQAQGAQLTAQLASLTALNATLQQQDQ 513
Cdd:COG1196    374 LAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAE 453

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  514 ELTSLKEQAKKEQAQMLQTLQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEAARQDHAQQLATI----------V 583
Cdd:COG1196    454 LEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLagavavligvE 533

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  584 EAREASVRERDAARQQLETLEKEKDAKleSLQQQLQASNEARDTAQTSVTQAQREKAELSQKIGELHACIEAAHQEQRQA 663
Cdd:COG1196    534 AAYEAALEAALAAALQNIVVEDDEVAA--AAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREA 611

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  664 QAHVTELEAQLKAEQQKAT-------------EREKVVQEKVQLQEQLQALEETLKIVRGSLEEEKCRAADALKEQQRHA 730
Cdd:COG1196    612 DARYYVLGDTLLGRTLVAArleaalrravtlaGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEE 691

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  731 TEMEAETRHLMEQREQEQKELEQEKAERKGLEARLQQLEEAHQAETEALRHELAGATAAqhgAESEREQLLREVESWQKR 810
Cdd:COG1196    692 ELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEE---EALEELPEPPDLEELERE 768

                          570
                   ....*....|...
gi 1958645968  811 VEARQQEEARYGA 823
Cdd:COG1196    769 LERLEREIEALGP 781
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1115-1679 6.01e-19

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 94.23  E-value: 6.01e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1115 EVEALRAEISKLERQWQqqqqqveglthsleseracraEQDKALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQ 1194
Cdd:COG1196    226 EAELLLLKLRELEAELE---------------------ELEAELEELEAELEELEAELAELEAELEELRLELEELELELE 284

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1195 DHSKAEEEWKAQVARGQQEAERKSSLISSLEEEVSILNRQVLEKEGESKELKRLVVAESEKSQKLEERLRLLQVETASSS 1274
Cdd:COG1196    285 EAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAE 364

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1275 ARAAERSSALREEVQSLREEVEKQrvvsENLRQELASQAERAEESGQELKAWQEKFFQKEQALSALQLEHTSTQALVSEL 1354
Cdd:COG1196    365 EALLEAEAELAEAEEELEELAEEL----LEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEE 440

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1355 LPAKHLCQQLQAEQAAAEKRFREEIEQSKQAAGGLQAELMRAQRELGELGSlRQKIVEQERAAQQLRAEKASYAEQLSML 1434
Cdd:COG1196    441 EEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAA-RLLLLLEAEADYEGFLEGVKAALLLAGL 519

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1435 KKAHGLLAEENRG-------LGERANLGRQFLEVELDQAREKYVQELAAVRTDAETHL---AEMRQEAQSTSRELEVMTA 1504
Cdd:COG1196    520 RGLAGAVAVLIGVeaayeaaLEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLpldKIRARAALAAALARGAIGA 599

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1505 KYESAKVKVLEERQRFQEERQKLTAQVEELNKKLTESEQASRVQQQKLKAFQAQGGESQ-------QEVQCLQTQLSELQ 1577
Cdd:COG1196    600 AVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAggsltggSRRELLAALLEAEA 679

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1578 AQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQELREQLQDLEQLQKDNKELRSETERLGRELQQAGLKTKEAEQACRHLT 1657
Cdd:COG1196    680 ELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEP 759

                          570       580
                   ....*....|....*....|..
gi 1958645968 1658 AQVRSLEAQVAHADQQLRDLGK 1679
Cdd:COG1196    760 PDLEELERELERLEREIEALGP 781
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 695-1544 7.38e-18

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 90.89  E-value: 7.38e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  695 QEQLQALEETLKIVRGSLEEEKCRAADALKEQQRHATEMEAETRHLMEQREQEQKEleqeKAERKGLEARLQQLEEAHQA 774
Cdd:TIGR02168  185 RENLDRLEDILNELERQLKSLERQAEKAERYKELKAELRELELALLVLRLEELREE----LEELQEELKEAEEELEELTA 260

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  775 ETEALRHELAGATAAQHGAESEREQLLREVESWQKRVEARQQEEARYgamfQEQLMALKgehgkiGQEEQKEAGEIHGEG 854
Cdd:TIGR02168  261 ELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQIL----RERLANLE------RQLEELEAQLEELES 330

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  855 QTGQQQSQLAQLHACLAKALQQVQEKEARAQKLLDDLSALREKMAATNKEVACLKALVLKAGEQQAAASHELKeppRAGN 934
Cdd:TIGR02168  331 KLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIE---RLEA 407

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  935 QESDWEEEQARPLGSTQAALKAVQR-EAEQMGGELERLRAALMQSQGQQQEVRGQQER---EVARLTQERGQAQADLAQE 1010
Cdd:TIGR02168  408 RLERLEDRRERLQQEIEELLKKLEEaELKELQAELEELEEELEELQEELERLEEALEElreELEEAEQALDAAERELAQL 487

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1011 KAAKAELEMRLQNTLNEQRVEFAALQEAltHAMTEKEGKDQELAKLREQEAAQISelKALQQTLEELKKkekehptggaR 1090
Cdd:TIGR02168  488 QARLDSLERLQENLEGFSEGVKALLKNQ--SGLSGILGVLSELISVDEGYEAAIE--AALGGRLQAVVV----------E 553

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1091 GEDASGDGPGSQLHTPGKTEAPGPEVEALRAEISKLERQWQQQQQQVEGLTHSLESeraCRAEQDKALETLQGQL----- 1165
Cdd:TIGR02168  554 NLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVK---FDPKLRKALSYLLGGVlvvdd 630

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1166 ----EEKARELGHNQA-----------------ASASAQRELQALRAKAQDHSKAEEEWKAQVARGQQEAERKSSLISSL 1224
Cdd:TIGR02168  631 ldnaLELAKKLRPGYRivtldgdlvrpggvitgGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKELEEL 710

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1225 EEEVSILNRQVLEKEGESKELKRLVVAESEKSQKLEERLRLLQVEtasssaraaerSSALREEVQSLREEVEKQRVVSEN 1304
Cdd:TIGR02168  711 EEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKE-----------LTELEAEIEELEERLEEAEEELAE 779

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1305 LRQELASQAERAEESGQELKAWQEKFFQKEQALSALQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKRFREEIEQSKQ 1384
Cdd:TIGR02168  780 AEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAA 859

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1385 AAGGLQAELMRAQRELGELGSLRQKIvEQERAAQQLRAEKASyAEQLSMLKKAHGL--LAEENRGLGERANLGRQFLEVE 1462
Cdd:TIGR02168  860 EIEELEELIEELESELEALLNERASL-EEALALLRSELEELS-EELRELESKRSELrrELEELREKLAQLELRLEGLEVR 937

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1463 LDQAREKYVQELAAVRTDAETHLAEMRQEAQSTSRELEVMTAKYES---AKVKVLEERQRFQEERQKLTAQVEELNKKLT 1539
Cdd:TIGR02168  938 IDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKElgpVNLAAIEEYEELKERYDFLTAQKEDLTEAKE 1017


                   ....*
gi 1958645968 1540 ESEQA 1544
Cdd:TIGR02168 1018 TLEEA 1022
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 456-1266 3.47e-17

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 88.58  E-value: 3.47e-17
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  456 EEEKRQLASLVADLQSSVSNLSQAKEELQQASQAQGAqLTAQLASLTALNATLQQQDQELTSLKEQAKKEQAQMLQTLQE 535
Cdd:TIGR02168  221 ELRELELALLVLRLEELREELEELQEELKEAEEELEE-LTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISR 299

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  536 QEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKeqeaaRQDHAQQLATIVEAREASVRERdaaRQQLETLEKEKDAKLESLQ 615
Cdd:TIGR02168  300 LEQQKQILRERLANLERQLEELEAQLEELES-----KLDELAEELAELEEKLEELKEE---LESLEAELEELEAELEELE 371

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  616 QQLQASNEARDTAQTSVTQAQREKAELSQKIGELHACIEAAHQEQRQAQAHVTELEAQLKAEQQKATER--EKVVQEKVQ 693
Cdd:TIGR02168  372 SRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAelEELEEELEE 451

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  694 LQEQLQALEETLKIVRGSLEEEKCRAADALKEQQRHATEMEAeTRHLMEQREQEQKELEQEKAERKGLEARLQQLEEAHQ 773
Cdd:TIGR02168  452 LQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDS-LERLQENLEGFSEGVKALLKNQSGLSGILGVLSELIS 530

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  774 AETEalrHELAGATAAQHGAESereQLLREVESWQKRVEARQQEEARYGAMFqeqlmalkgehgkigqeeqkEAGEIHGE 853
Cdd:TIGR02168  531 VDEG---YEAAIEAALGGRLQA---VVVENLNAAKKAIAFLKQNELGRVTFL--------------------PLDSIKGT 584

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  854 GQTGQQQSQLAQLHACLAKALQQVqEKEARAQKLLDDLSA-------------LREKMAATNKEVAcLKALVLKAGEQQA 920
Cdd:TIGR02168  585 EIQGNDREILKNIEGFLGVAKDLV-KFDPKLRKALSYLLGgvlvvddldnaleLAKKLRPGYRIVT-LDGDLVRPGGVIT 662

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  921 AAShelkEPPRAGNQESDWE--------EEQARPLGSTQAALKAVQREAEQMGGELERLRAALMQSQGQQQEvrgqQERE 992
Cdd:TIGR02168  663 GGS----AKTNSSILERRREieeleekiEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISA----LRKD 734

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  993 VARLTQERGQAQADLAQEKAAKAELEMRLQNTLNEQRVEFAALQEALthamTEKEGKDQELAKLREQEAAQISELKALQQ 1072
Cdd:TIGR02168  735 LARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAE----AEIEELEAQIEQLKEELKALREALDELRA 810

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1073 TLEELKKKEKEHPTGGARGEDASGDGPGSQLHTPGKTEAPGPEVEALRAEISKLERQWQQQQQQVEGLTHSLESERACRA 1152
Cdd:TIGR02168  811 ELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALA 890

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1153 EQDKALETLQGQLEEKARELGhnqaasaSAQRELQALRAKAQDHSKAEEEWKAQVAR--------GQQEAERKSSLISSL 1224
Cdd:TIGR02168  891 LLRSELEELSEELRELESKRS-------ELRRELEELREKLAQLELRLEGLEVRIDNlqerlseeYSLTLEEAEALENKI 963

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|..
gi 1958645968 1225 EEEVSILNRQVLEKEGESKELKRLVVAESEKSQKLEERLRLL 1266
Cdd:TIGR02168  964 EDDEEEARRRLKRLENKIKELGPVNLAAIEEYEELKERYDFL 1005
PTZ00121 PTZ00121
MAEBL; Provisional
 265-943 2.23e-16

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 86.35  E-value: 2.23e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  265 KQAASPQEPSELEELRGKNESLTV----RLHETLKQCQNLKTEKNQMDRKISQLSEENGDLSFKVREFANHLQQLQGAfn 340
Cdd:PTZ00121  1203 EAARKAEEERKAEEARKAEDAKKAeavkKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKA-- 1280

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  341 dliEEHSKASQEWAEKQAHLESELSTALQDKKCLEE--KSEILQEKISQLEDRAAQLQgspapEKGEVLGDALQLDTLKQ 418
Cdd:PTZ00121  1281 ---DELKKAEEKKKADEAKKAEEKKKADEAKKKAEEakKADEAKKKAEEAKKKADAAK-----KKAEEAKKAAEAAKAEA 1352

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  419 EAAKLATDNTELQARVETLECERGKQEAQLLAERGHFEEEKRQLASLVADLQSSVSNLSQAKEELQQASQAQGAQLTAQL 498
Cdd:PTZ00121  1353 EAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKK 1432

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  499 ASLTALNATLQQQDQELTSLKEQAKKeqAQMLQTLQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEAARQDHAQQ 578
Cdd:PTZ00121  1433 ADEAKKKAEEAKKADEAKKKAEEAKK--AEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKK 1510

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  579 LATivEAREAS-VRERDAARQQLETLEKEKDAKLESLQQ--QLQASNEARDTAQTSVTQAQREKAELSQKIGELHACIEA 655
Cdd:PTZ00121  1511 KAD--EAKKAEeAKKADEAKKAEEAKKADEAKKAEEKKKadELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKK 1588

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  656 AHQEQRQAQAHVTELEAQLKAEQQKATEREKVVQEKVQLQEQLQALEETLKivrGSLEEEKCRAADALKEQQRHATEMEA 735
Cdd:PTZ00121  1589 AEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLK---KKEAEEKKKAEELKKAEEENKIKAAE 1665

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  736 ETRHLMEQREQEQKELEQEKAERKGLEARLQQLEEAHQAETEALRHELAGATAAQHGAESEREQLLREVESWQKRVEARQ 815
Cdd:PTZ00121  1666 EAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKK 1745

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  816 QEEARYGAMFQEQLMALKGEHGKIGQEEQKEAGEIHGEGQTGQQQSQLAQLHACLAKALQQVQEKEARAQKLLDDLSALR 895
Cdd:PTZ00121  1746 AEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKKIKDIFDNFANIIEGGKEGNLVINDSK 1825

                          650       660       670       680
                   ....*....|....*....|....*....|....*....|....*....
gi 1958645968  896 EKMAATNKEVACLKALVL-KAGEQQAAASHELKEPPRAGNQESDWEEEQ 943
Cdd:PTZ00121  1826 EMEDSAIKEVADSKNMQLeEADAFEKHKFNKNNENGEDGNKEADFNKEK 1874
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 412-1072 2.48e-16

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 85.88  E-value: 2.48e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  412 QLDTLKQEAaKLATDNTELQARVETLEC--------ERGKQEAQLLAERGHFEEEKRQLASLVADLQSSVSNLSQAKEEL 483
Cdd:TIGR02168  201 QLKSLERQA-EKAERYKELKAELRELELallvlrleELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSEL 279

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  484 QQASQAQGAQLTAQLASLTALNATLQQQDQELTSLKEQAKKEQAQML---QTLQEQEQAAQGLRQQVEQLSSSLKLKEQQ 560
Cdd:TIGR02168  280 EEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEeleSKLDELAEELAELEEKLEELKEELESLEAE 359

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  561 LEEAAkeqeAARQDHAQQLATIVEAREASVRERDAARQQLETLEKEkdakLESLQQQLQASNEARDTAQTSVTQAQREKA 640
Cdd:TIGR02168  360 LEELE----AELEELESRLEELEEQLETLRSKVAQLELQIASLNNE----IERLEARLERLEDRRERLQQEIEELLKKLE 431

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  641 ElsQKIGELHACIEAAHQEQRQAQAHVTELEAQLKAEQQKATEREKVVQEKVQLQEQLQALEETLKIVRGSLEEEKCRAA 720
Cdd:TIGR02168  432 E--AELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVK 509

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  721 DALKEQQRHATemeaetrHLMEQREQEQKELEQEKAERKGLEARLQQL----EEAHQAETEALRHELAGATA-------- 788
Cdd:TIGR02168  510 ALLKNQSGLSG-------ILGVLSELISVDEGYEAAIEAALGGRLQAVvvenLNAAKKAIAFLKQNELGRVTflpldsik 582

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  789 AQHGAESEREQL---------LREVESWQKRVEA-------------------RQQEEARYGAMFQEQLMALKGEHGKI- 839
Cdd:TIGR02168  583 GTEIQGNDREILkniegflgvAKDLVKFDPKLRKalsyllggvlvvddldnalELAKKLRPGYRIVTLDGDLVRPGGVIt 662

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  840 GQEEQKEAG------EI-HGEGQTGQQQSQLAQLHACLAKALQQVQEKEARAQKLLDDLSALREKMAATNKEVACLKALV 912
Cdd:TIGR02168  663 GGSAKTNSSilerrrEIeELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEV 742

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  913 LKAGEQQAAASHELKEPPRAGNQESDWEEEQARPLGSTQAALKAVQREAEQMGGELERLRAALMQSQGQQQEVR---GQQ 989
Cdd:TIGR02168  743 EQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNeeaANL 822

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  990 EREVARLTQERGQAQA---DLAQEKAAKAELEMRLQNTLNEQRVEFAALQEALTHAMTEKEGKDQELAKLREQEAAQISE 1066
Cdd:TIGR02168  823 RERLESLERRIAATERrleDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEE 902


                   ....*.
gi 1958645968 1067 LKALQQ 1072
Cdd:TIGR02168  903 LRELES 908
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1003-1679 2.64e-16

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 85.88  E-value: 2.64e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1003 AQADLAQEKAAKAELEMRLqNTLNEQR---VEFAALQEALTHA-----MTEKEGKDQELAKLREQEAAQISELKALQQTL 1074
Cdd:TIGR02168  184 TRENLDRLEDILNELERQL-KSLERQAekaERYKELKAELRELelallVLRLEELREELEELQEELKEAEEELEELTAEL 262

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1075 EELKKKEKEHPTGGARGEDASGDGPGsqlhtpgkteapgpEVEALRAEISKLERQWQQQQQQVEGLTHSLEseracraEQ 1154
Cdd:TIGR02168  263 QELEEKLEELRLEVSELEEEIEELQK--------------ELYALANEISRLEQQKQILRERLANLERQLE-------EL 321

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1155 DKALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQDHSKAEEEWKAQVARGQQEAERKSSLISSLEEEVSILNrq 1234
Cdd:TIGR02168  322 EAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLN-- 399

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1235 vlekegeskelKRLVVAESEKSQKLEERLRLLQVETASSSARAAERSSALREEVQSLREEVEKQRVVSENLRQELASQAE 1314
Cdd:TIGR02168  400 -----------NEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELRE 468

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1315 RAEESGQELKAWQEKFFQKEQ---ALSALQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKrFREEIEQSKQAAGG--L 1389
Cdd:TIGR02168  469 ELEEAEQALDAAERELAQLQArldSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELIS-VDEGYEAAIEAALGgrL 547

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1390 QAELMR------------AQRELG-------------ELGSLRQKIVEQERAAQQLRAEKASYAEQLSM----------- 1433
Cdd:TIGR02168  548 QAVVVEnlnaakkaiaflKQNELGrvtflpldsikgtEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKalsyllggvlv 627

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1434 ---LKKAHGLLAEENRGL-------------------GERANLGRQFLEVELDQAREKY-------------VQELAAVR 1478
Cdd:TIGR02168  628 vddLDNALELAKKLRPGYrivtldgdlvrpggvitggSAKTNSSILERRREIEELEEKIeeleekiaelekaLAELRKEL 707

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1479 TDAETHLAEMRQEAQSTSRELEVMTAKYESAKVKV---LEERQRFQEERQKLTAQVEELNKKLTESEQASRVQQQKLKAF 1555
Cdd:TIGR02168  708 EELEEELEQLRKELEELSRQISALRKDLARLEAEVeqlEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEEL 787

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1556 QAQGGESQQEVQCLQTQLSELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQELREQLQD-----------LEQLQKD 1624
Cdd:TIGR02168  788 EAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEElsedieslaaeIEELEEL 867

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1958645968 1625 NKELRSETERLGRELQQAGLKTKEAEQACRHLTAQVRSLEAQVAHADQQLRDLGK 1679
Cdd:TIGR02168  868 IEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELRE 922
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 841-1404 2.65e-16

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 85.37  E-value: 2.65e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  841 QEEQKEAGEIHGEGQTGQQQSQLAQLHACLAKALQQVQEKEARAQKLLDDLSALREKMAATNKEVACLKALVLKAGEQQA 920
Cdd:COG1196    240 ELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLE 319

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  921 AASHELKEppragnqesdWEEEQARpLGSTQAALKAVQREAEQMGGELERLRAALMQSQGQQQEVRGQQEREVARLTQER 1000
Cdd:COG1196    320 ELEEELAE----------LEEELEE-LEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEEL 388

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1001 GQAQADLAQEKAAKAELEMRLQNTLNEQRVEFAALQEALTHAMTEKEGKDQELAKLREQEAAQISELKALQQTLEELKKK 1080
Cdd:COG1196    389 LEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAEL 468

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1081 EKEHPTGGARGEDAsgDGPGSQLHTPGKTEAPGPEVEALRAEISKLERQWQQQQqqveGLTHSLESERACRAEQDKALET 1160
Cdd:COG1196    469 LEEAALLEAALAEL--LEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLR----GLAGAVAVLIGVEAAYEAALEA 542

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1161 -LQGQLEEKARELGHNQAASASAQRELQALRAKAQDHSKAEEEWKAQVARGQQEAERKSSLISSLEEEVSILNRQVLEKE 1239
Cdd:COG1196    543 aLAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTL 622

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1240 GESKELKRLVVAESEKSQKLEERLRLLQVETASSSARAAERSSALREEVQSLREEVEKQRVVSENLRQELASQAERAEES 1319
Cdd:COG1196    623 LGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAE 702

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1320 GQELKawqekffQKEQALSALQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKRFREEIEQSKQAAGGLQAELMRAQRE 1399
Cdd:COG1196    703 EEEER-------ELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLERE 775


                   ....*
gi 1958645968 1400 LGELG 1404
Cdd:COG1196    776 IEALG 780
PTZ00121 PTZ00121
MAEBL; Provisional
 959-1650 2.70e-16

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 85.96  E-value: 2.70e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  959 REAEQMGGELERLRAALMQSQGQQQEVRGQQER----EVARLTQERGQAQADLAQEKAAKAELEMRLQNTlneQRVEFAA 1034
Cdd:PTZ00121  1088 RADEATEEAFGKAEEAKKTETGKAEEARKAEEAkkkaEDARKAEEARKAEDARKAEEARKAEDAKRVEIA---RKAEDAR 1164

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1035 LQEALTHAmteKEGKDQELAKlREQEAAQISELKALQQTLEELKKKEKEHPTggaRGEDASGDGPGSQLHTPGKTE-APG 1113
Cdd:PTZ00121  1165 KAEEARKA---EDAKKAEAAR-KAEEVRKAEELRKAEDARKAEAARKAEEER---KAEEARKAEDAKKAEAVKKAEeAKK 1237

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1114 PEVEALRAEisKLERQWQQQQQQVEGLTHSLESERACRAEQDKALETLQGQLEEKARElghnQAASASAQRELQALRAKA 1193
Cdd:PTZ00121  1238 DAEEAKKAE--EERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKAD----EAKKAEEKKKADEAKKKA 1311

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1194 QDHSKAEE--------EWKAQVARGQQEAERKSSLISSLEEEVSILNRQVLEKEGESKELKRlvvaESEKSQKLEERLRL 1265
Cdd:PTZ00121  1312 EEAKKADEakkkaeeaKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKK----EEAKKKADAAKKKA 1387

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1266 LQVETASSSARAAERSSALREEVQslREEVEKQRVVSENLRQELASQAERAEESGQELKAWQEKFFQKEQALSALQLEHT 1345
Cdd:PTZ00121  1388 EEKKKADEAKKKAEEDKKKADELK--KAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKK 1465

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1346 STQALVSELLPAKHLCQQLQAEQAAAEKRFREEIEQSKQAA-GGLQAELMRAQRELGELGSLRQkiVEQERAAQQLR-AE 1423
Cdd:PTZ00121  1466 AEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAeAKKKADEAKKAEEAKKADEAKK--AEEAKKADEAKkAE 1543

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1424 KASYAEQLSM---LKKAHGLL-AEENRGLGERANLGRQFLEvELDQAREKYVQELAAVRTDAETHLAEMRQEAQStsrel 1499
Cdd:PTZ00121  1544 EKKKADELKKaeeLKKAEEKKkAEEAKKAEEDKNMALRKAE-EAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEE----- 1617

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1500 evmtAKYESAKVKVLEERQRFQEERQKltaQVEELNKKLTESEQASrvQQQKLKAFQAQGGESQQevqclQTQLSELQAQ 1579
Cdd:PTZ00121  1618 ----AKIKAEELKKAEEEKKKVEQLKK---KEAEEKKKAEELKKAE--EENKIKAAEEAKKAEED-----KKKAEEAKKA 1683

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1958645968 1580 LSQKEQAAEHYKLQMEKAKTHYDAKKQQNQELREQlqdlEQLQKDNKELRSETERLGRELQQAGLKTKEAE 1650
Cdd:PTZ00121  1684 EEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKA----EELKKAEEENKIKAEEAKKEAEEDKKKAEEAK 1750
PTZ00121 PTZ00121
MAEBL; Provisional
 343-1072 5.72e-16

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 84.81  E-value: 5.72e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  343 IEEHSKASQEWAEKQAHLESELSTALQDKKCLEEKSEILQEKISQLEDRAAQLQGSPAPEKGEvlgDALQLDTLKQEAAK 422
Cdd:PTZ00121  1111 AEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAEDAKRVEIARKAEDARKAEEARKAE---DAKKAEAARKAEEV 1187

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  423 LATDNTELQARVETLECERGKQEAQLLAERGHFEEEKRQLASLVADLQSSVSNLSQAKEELQQASQAQGAQLTAQLASLT 502
Cdd:PTZ00121  1188 RKAEELRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFAR 1267

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  503 ALNATLQQQDQELTSLKEQAKKEQAQMLQTLQEQEQAAQgLRQQVEQLSSSLKLKEQQLEEAAKEQEAARQDHAQQlati 582
Cdd:PTZ00121  1268 RQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADE-AKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAK---- 1342

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  583 vEAREASVRERDAARQQLETLEKEKDAKLESLQQQLQASNEARDTAQ--TSVTQAQREKAELSQKIGELHACIEA---AH 657
Cdd:PTZ00121  1343 -KAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEekKKADEAKKKAEEDKKKADELKKAAAAkkkAD 1421

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  658 QEQRQAQAHVTELEAQLKAEQ-QKATEREKVVQEKVQLQEQLQALEETLKIVRGSLEEEKCRAADALKEQqrhATEMEAE 736
Cdd:PTZ00121  1422 EAKKKAEEKKKADEAKKKAEEaKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKK---AEEAKKK 1498

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  737 TRHLMEQREQEQKELEQEKAERKGLEARLQQLEEAHQAETEALRHELAGATAAQHGAESEREQLLREVE----------- 805
Cdd:PTZ00121  1499 ADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEeakkaeedknm 1578

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  806 SWQKRVEARQQEEARYGAMFQ--EQLMALKGEHGKIGQEEQKEAGEIHGEGQTGQQQSQLAQLHACLAKALQQVQE---- 879
Cdd:PTZ00121  1579 ALRKAEEAKKAEEARIEEVMKlyEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKaeee 1658

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  880 ----KEARAQKLLDDLSALREKMAATNKEVACLKALVLKAGEQQAAASHELKEPPRAGNQESDWEEEQARPLGSTQAalk 955
Cdd:PTZ00121  1659 nkikAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEA--- 1735

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  956 avQREAEQMGGELERLRaalmQSQGQQQEVRGQQEREVARLTQERGQAQADLAQEKAAKAE-LEMRLQNTLNEQRVEFAA 1034
Cdd:PTZ00121  1736 --KKEAEEDKKKAEEAK----KDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEDEkRRMEVDKKIKDIFDNFAN 1809

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|..
gi 1958645968 1035 LQEA----LTHAMTEKEGKDQELAKLREQEAAQISELKALQQ 1072
Cdd:PTZ00121  1810 IIEGgkegNLVINDSKEMEDSAIKEVADSKNMQLEEADAFEK 1851
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 938-1663 4.74e-15

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 81.64  E-value: 4.74e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  938 DWEEEQARpLGSTQAALKAVQREAEQMGGELERLRAALMQSQGQQQEVRGQQEREVARLtQERGQAQADLAQEKAAKAEL 1017
Cdd:TIGR02168  233 RLEELREE-LEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKEL-YALANEISRLEQQKQILRER 310

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1018 EMRLQNT---LNEQRVEFAALQEALTHAMTEKEGKDQELAKLREQEAAQISELKALQQTLEELKKKEKEHPTGGARGEDA 1094
Cdd:TIGR02168  311 LANLERQleeLEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQ 390

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1095 sgdgpgsqlhtpgkteaPGPEVEALRAEISKLERQWQQQQQQVEGLTHSLESERacRAEQDKALETLQGQLEEKARELGH 1174
Cdd:TIGR02168  391 -----------------LELQIASLNNEIERLEARLERLEDRRERLQQEIEELL--KKLEEAELKELQAELEELEEELEE 451

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1175 NQAASASAQRELQALRAKAQDHSKAEEEWKAQVARGQQEAErksslissleeevsILNRQVLEKEGESKELKRLVVAESE 1254
Cdd:TIGR02168  452 LQEELERLEEALEELREELEEAEQALDAAERELAQLQARLD--------------SLERLQENLEGFSEGVKALLKNQSG 517

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1255 KSQKLEERLRLLQVETASSSARAAerssALREEVQSLreevekqrVVSENLRQELASQAERAEESGQ----ELKAWQEKF 1330
Cdd:TIGR02168  518 LSGILGVLSELISVDEGYEAAIEA----ALGGRLQAV--------VVENLNAAKKAIAFLKQNELGRvtflPLDSIKGTE 585

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1331 FQKEQALSALQLEHTSTQALVSELLPAK-HLCQQLQAEQAAAEKRFREEIEQSKQAAGG-----LQAELMR--------- 1395
Cdd:TIGR02168  586 IQGNDREILKNIEGFLGVAKDLVKFDPKlRKALSYLLGGVLVVDDLDNALELAKKLRPGyrivtLDGDLVRpggvitggs 665

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1396 AQRELG------ELGSLRQKIVEQERAAQQLRAEKASYAEQLSMLKKAHGLLAEENRGLGERANLGRQFLEVEldqarEK 1469
Cdd:TIGR02168  666 AKTNSSilerrrEIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARL-----EA 740

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1470 YVQELAAVRTDAETHLAEMRQEAQSTSRELEVMTAKYESAKVKVL---EERQRFQEERQKLTAQVEELNKKLTESEQASR 1546
Cdd:TIGR02168  741 EVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEeleAQIEQLKEELKALREALDELRAELTLLNEEAA 820

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1547 VQQQKLKAFQAQGGESQQEVQCLQTQLSELQAQLSQKEQAAEHYKLQMEKA----KTHYDAKKQQNQELREQLQDLEQLQ 1622
Cdd:TIGR02168  821 NLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELeselEALLNERASLEEALALLRSELEELS 900

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....*...
gi 1958645968 1623 KD-------NKELRSETERLGRELQQAGLKTKEAEQACRHLTAQVRSL 1663
Cdd:TIGR02168  901 EElreleskRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEE 948
PTZ00121 PTZ00121
MAEBL; Provisional
 1147-1652 8.87e-15

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 80.96  E-value: 8.87e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1147 ERACRAEQDKALETLQGQLE-EKARELGH-NQAASASAQRELQALRaKAQDHSKAEEEWKAQVARGQQEAERKSSLISSL 1224
Cdd:PTZ00121  1167 EEARKAEDAKKAEAARKAEEvRKAEELRKaEDARKAEAARKAEEER-KAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKA 1245

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1225 EEEVSILNRQVLEKEGESKELKRLVVAESEKSQKLEERLRLLQVETASSSARAAERSSAlrEEVQSLREEVEKQRVVSEN 1304
Cdd:PTZ00121  1246 EEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKA--DEAKKKAEEAKKADEAKKK 1323

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1305 lRQELASQAERAEESGQELKAWQEKFFQKEQAlSALQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKRFREEIEQSKQ 1384
Cdd:PTZ00121  1324 -AEEAKKKADAAKKKAEEAKKAAEAAKAEAEA-AADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAE 1401

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1385 AAGGLQAELMRAQRELGELGSLRQKIVEQERAAQ-QLRAEKASYAEQLSmlKKAHGLLAEENrgLGERANLGRQFLEVEL 1463
Cdd:PTZ00121  1402 EDKKKADELKKAAAAKKKADEAKKKAEEKKKADEaKKKAEEAKKADEAK--KKAEEAKKAEE--AKKKAEEAKKADEAKK 1477

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1464 DQAREKYVQELAAVRTDAETHLAEMRQ--EAQSTSRELEVMTAKYESAKVKVLEERQRFQEERQ-KLTAQVEELNK--KL 1538
Cdd:PTZ00121  1478 KAEEAKKADEAKKKAEEAKKKADEAKKaaEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKaEEKKKADELKKaeEL 1557

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1539 TESEQASRVQQQK----------LKAFQAQGGESQ--QEVQCLQTQLSELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQ 1606
Cdd:PTZ00121  1558 KKAEEKKKAEEAKkaeedknmalRKAEEAKKAEEAriEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQ 1637

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|....*.
gi 1958645968 1607 QNQELREQLQDLEQLQKDNKELRSETERLGRELQQAGLKTKEAEQA 1652
Cdd:PTZ00121  1638 LKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKA 1683
PTZ00121 PTZ00121
MAEBL; Provisional
 942-1634 1.91e-14

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 79.80  E-value: 1.91e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  942 EQARPLGSTQAALKAVQREAEQMGGELERLRAALMQSQGQQ-QEVRGQQE---REVARLTQERGQAQADLAQEKAAKAEL 1017
Cdd:PTZ00121  1101 EEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKaEEARKAEDakrVEIARKAEDARKAEEARKAEDAKKAEA 1180

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1018 EMRLQNTLNEQRVEFAALQEALTHAMTEKEGKDQELAKlREQEAAQISELKALQQTLEELKKKEKEHPTggaRGEDASGD 1097
Cdd:PTZ00121  1181 ARKAEEVRKAEELRKAEDARKAEAARKAEEERKAEEAR-KAEDAKKAEAVKKAEEAKKDAEEAKKAEEE---RNNEEIRK 1256

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1098 GPGSQLHTPGKTEAPGPEVEALRA-EISKLERQWqqqqqqveglthslESERACRAEQDKALETLQGQLEEKaRELGHNQ 1176
Cdd:PTZ00121  1257 FEEARMAHFARRQAAIKAEEARKAdELKKAEEKK--------------KADEAKKAEEKKKADEAKKKAEEA-KKADEAK 1321

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1177 AASASAQRELQALRAKAQDHSKAEEEWKAQVARGQQEAERKSSLISSLEEEVSILNRQVLEKEGESKELKRlvvAESEKS 1256
Cdd:PTZ00121  1322 KKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKK---ADEAKK 1398

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1257 QKLEERLRLLQVETASSSARAAERSSALREEVQ---SLREEVEKQRVVSE-NLRQELASQAERAEESGQELKAWQEKFFQ 1332
Cdd:PTZ00121  1399 KAEEDKKKADELKKAAAAKKKADEAKKKAEEKKkadEAKKKAEEAKKADEaKKKAEEAKKAEEAKKKAEEAKKADEAKKK 1478

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1333 KEQALSALQLEHTSTQAL--VSELLPAKHLCQQLQAEQAAAEKRFREEI---EQSKQAAGGLQAELMRAQRELGELGSLR 1407
Cdd:PTZ00121  1479 AEEAKKADEAKKKAEEAKkkADEAKKAAEAKKKADEAKKAEEAKKADEAkkaEEAKKADEAKKAEEKKKADELKKAEELK 1558

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1408 Q----KIVEQERAAQQLRAEKASYAEQLSMLKKAH-----GLLAEENRGLGERANLGRQFL----EVELDQAREKYVQEL 1474
Cdd:PTZ00121  1559 KaeekKKAEEAKKAEEDKNMALRKAEEAKKAEEARieevmKLYEEEKKMKAEEAKKAEEAKikaeELKKAEEEKKKVEQL 1638

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1475 AAVRTDAETHLAEMRQEAQSTSRELEVMTAKYESAKVKVLEERQRFQEERQKLTAQVEELNKKLTESEQASRVQQQKLKA 1554
Cdd:PTZ00121  1639 KKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKA 1718

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1555 FQAQGGESQQEVQCLQTQLSELQaqlsQKEQAAEHYKLQMEKAKTHYDAKKQQN--QELREQLQDL--EQLQKDNKELRS 1630
Cdd:PTZ00121  1719 EELKKAEEENKIKAEEAKKEAEE----DKKKAEEAKKDEEEKKKIAHLKKEEEKkaEEIRKEKEAVieEELDEEDEKRRM 1794


                   ....
gi 1958645968 1631 ETER 1634
Cdd:PTZ00121  1795 EVDK 1798
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 335-1313 5.95e-14

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 77.80  E-value: 5.95e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  335 LQGAFNDLIEEHSKASQEWAEKQA---HLESELSTALQDKKCLEEKSEILQEKISQLEDRAAQLQGSPApekgevlgDAL 411
Cdd:TIGR02169  140 LQGDVTDFISMSPVERRKIIDEIAgvaEFDRKKEKALEELEEVEENIERLDLIIDEKRQQLERLRRERE--------KAE 211

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  412 QLDTLKQEaaKLATDNTELQARVETLECERGKQEAQLLAERGHFEEEKRQLASLVADLQSSVSNLSQAKEELQQASQAQG 491
Cdd:TIGR02169  212 RYQALLKE--KREYEGYELLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQ 289

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  492 AQLTAQLASLTALNATLQQQDQELTSLKEQAKKEQAQMLQTLQEQEQAAQGLRQQVEQLSsslKLKEQqleeaakeqeaa 571
Cdd:TIGR02169  290 LRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEER---KRRDK------------ 354

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  572 rqdhaqqLATIVEAREAsvrERDAARQQLETLEKEKDA---KLESLQQQLQASNEARDTAQTSVTQAQREKAELSQKIGE 648
Cdd:TIGR02169  355 -------LTEEYAELKE---ELEDLRAELEEVDKEFAEtrdELKDYREKLEKLKREINELKRELDRLQEELQRLSEELAD 424

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  649 LHACIEAAHQEQRQAQAHVTELEAQLKAEQQKateREKVVQEKVQLQEQLQALEETLKIVRgsleeekcraaDALKEQQR 728
Cdd:TIGR02169  425 LNAAIAGIEAKINELEEEKEDKALEIKKQEWK---LEQLAADLSKYEQELYDLKEEYDRVE-----------KELSKLQR 490

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  729 HATEMEAETRHLMEQREQEQKELEQEKAERKG---LEARLQQLEEAHQAETE-ALRHELAGATAAQHGAESEREQLLREV 804
Cdd:TIGR02169  491 ELAEAEAQARASEERVRGGRAVEEVLKASIQGvhgTVAQLGSVGERYATAIEvAAGNRLNNVVVEDDAVAKEAIELLKRR 570

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  805 eswqkrvearqqeeaRYGAMFQEQLMALKgehgkigqEEQKEAGEIHGEGQTGQQQSqLAQLHACLAKALQQVqekeARA 884
Cdd:TIGR02169  571 ---------------KAGRATFLPLNKMR--------DERRDLSILSEDGVIGFAVD-LVEFDPKYEPAFKYV----FGD 622

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  885 QKLLDDLSALREKMAATNkevaclkaLVLKAGEqqaaasheLKEPPRAGNQESDweeeQARPLGSTQAALKAVQREAEQM 964
Cdd:TIGR02169  623 TLVVEDIEAARRLMGKYR--------MVTLEGE--------LFEKSGAMTGGSR----APRGGILFSRSEPAELQRLRER 682

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  965 GGELERLRAALMQsqgqqqevrgqqerEVARLTQERGQAQADLAQEKAAKAELEMRLQNTLNEQrvefAALQEALTHAMT 1044
Cdd:TIGR02169  683 LEGLKRELSSLQS--------------ELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEE----EKLKERLEELEE 744

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1045 EKEGKDQELAKLREQEAAQISELKALQQtleelkkkekehptggargedasgdgpgsqlhtpgkteapgpEVEALRAEIS 1124
Cdd:TIGR02169  745 DLSSLEQEIENVKSELKELEARIEELEE------------------------------------------DLHKLEEALN 782

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1125 KLERqwQQQQQQVEGLTHSLESERACRAEQDKALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQDHSKAEEEWK 1204
Cdd:TIGR02169  783 DLEA--RLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLN 860

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1205 AQVARGQQEAERKSSLISSLEEEVSILNRQVLEKEGESKELKRLVVAESEKSQKLEERLRLLQVETASSSARAAERSSAL 1284
Cdd:TIGR02169  861 GKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPK 940

                          970       980
                   ....*....|....*....|....*....
gi 1958645968 1285 REEVQSLREEVEKQRVVSENLRQELASQA 1313
Cdd:TIGR02169  941 GEDEEIPEEELSLEDVQAELQRVEEEIRA 969
PTZ00121 PTZ00121
MAEBL; Provisional
 514-1252 5.33e-13

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 75.18  E-value: 5.33e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  514 ELTSLKEQAKK--EQAQMLQTLQEQEQA--AQGLRQQVEQLSSSLKLKEQ---QLEEAAKEQEAARQDHAQQLATIVEAR 586
Cdd:PTZ00121  1112 EEARKAEEAKKkaEDARKAEEARKAEDArkAEEARKAEDAKRVEIARKAEdarKAEEARKAEDAKKAEAARKAEEVRKAE 1191

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  587 EasVRERDAARQQLETLEKEKDAKLESLQQqlqaSNEARDTAQTSVTQAQREKAELSQKIGELHACIEAAHQEQRQaQAH 666
Cdd:PTZ00121  1192 E--LRKAEDARKAEAARKAEEERKAEEARK----AEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEAR-MAH 1264

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  667 VTELEAQLKAEQQKATEREKVVQEKVQlQEQLQALEETLKIVRGSLEEEKCRAADALKEQQRHATEMEAETRhlmeqreq 746
Cdd:PTZ00121  1265 FARRQAAIKAEEARKADELKKAEEKKK-ADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAK-------- 1335

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  747 eqkeleqEKAERKglearlQQLEEAHQAETEALRHELAGATAAQHGAESEREQLLREVESWQKRV-EARQQEEARYGAMF 825
Cdd:PTZ00121  1336 -------KKAEEA------KKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAeEKKKADEAKKKAEE 1402

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  826 QEQlmalKGEHGKIGQEEQKEAGEIHGEGQTGQQqsqlaqlhaclAKALQQVQEKEARAQKLLDDLSALREKMAATNKEV 905
Cdd:PTZ00121  1403 DKK----KADELKKAAAAKKKADEAKKKAEEKKK-----------ADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAE 1467

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  906 ACLKALVLKAGEQQAAASHELKEPPRAGNQESDWEEEQARPLGSTQAALKAVQ-REAEQMGGELERLRAALMQSQGQQQE 984
Cdd:PTZ00121  1468 EAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEaKKADEAKKAEEAKKADEAKKAEEKKK 1547

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  985 VRGQQEREVARLTQERGQAQadlaQEKAAKAELEMRLQNTLNEQRVEFAALQEALTHAMTEKEGKDQELAKlREQEAAQI 1064
Cdd:PTZ00121  1548 ADELKKAEELKKAEEKKKAE----EAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKK-AEEAKIKA 1622

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1065 SELKALQQTLEELKKKEKEHPTGGARGEDASGDGPGSQLHTpgKTEAPGPEVEALRAEisKLERQWQQQQQQVEGLTHsl 1144
Cdd:PTZ00121  1623 EELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKA--AEEAKKAEEDKKKAE--EAKKAEEDEKKAAEALKK-- 1696

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1145 ESERACRAEQ-DKALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQDHSKAEEEwKAQVARGQQEAERKSsliss 1223
Cdd:PTZ00121  1697 EAEEAKKAEElKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEE-KKKIAHLKKEEEKKA----- 1770

                          730       740
                   ....*....|....*....|....*....
gi 1958645968 1224 leEEVSILNRQVLEKEGESKELKRLVVAE 1252
Cdd:PTZ00121  1771 --EEIRKEKEAVIEEELDEEDEKRRMEVD 1797
HkD_SF cd22211
Hook domain-containing proteins superfamily; The Hook domain superfamily includes Hook adaptor ...
 8-136 5.85e-13

Hook domain-containing proteins superfamily; The Hook domain superfamily includes Hook adaptor proteins, Hook-related proteins and nuclear mitotic apparatus protein (NuMA). They share an N-terminal conserved globular Hook domain, which folds as a variant of the helical calponin homology (CH) domain with an extended alpha-helix. The Hook domain is responsible for the binding of microtubule. The Hook family includes microtubule-binding proteins, Hook1-3. Hook1 is required for spermatid differentiation. Hook2 contributes to the establishment and maintenance of centrosome function. Hook3 is an adaptor protein for microtubule-dependent intracellular vesicle and protein trafficking, and is involved in Golgi and endosome transport. Hook proteins are components of the FTS/Hook/FHIP complex (FHF complex), which may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting (HOPS) complex. The Hook-related protein (HkRP) family includes Daple, Girdin and Gipie. Daple, also called Dvl-associating protein with a high frequency of leucine residues, or coiled-coil domain-containing protein 88C(CCDC88C), or Hook-related protein 2 (HkRP2), is a novel non-receptor nucleotide exchange factor (GEF) required for activation of guanine nucleotide-binding proteins (G-proteins) during non-canonical Wnt signaling. Girdin, also called Akt phosphorylation enhancer (APE), or coiled-coil domain-containing protein 88A (CCDC88A), or G alpha-interacting vesicle-associated protein (GIV), or Girders of actin filament, or Hook-related protein 1 (HkRP1), is a bifunctional modulator of guanine nucleotide-binding proteins (G proteins). Gipie, also called GRP78-interacting protein induced by ER stress, or coiled-coil domain-containing protein 88B(CCDC88B), or brain leucine zipper domain-containing protein, or Hook-related protein 3 (HkRP3), is a novel actin cytoskeleton-binding protein and Akt substrate that regulates cell migratory responses in various biological contexts. NuMA, also called nuclear mitotic apparatus protein 1, or nuclear matrix protein-22 (NMP-22), or SP-H antigen, is a microtubule (MT)-binding protein that plays a role in the formation and maintenance of the spindle poles and the alignment and the segregation of chromosomes during mitotic cell division.


Pssm-ID: 411792  Cd Length: 145  Bit Score: 68.07  E-value: 5.85e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968    8 ASTLLSWVNSLHVADPVETVLQLQDCSIFIKIINSI---HDTKEGQQILQQPLP-----ERLDFVCSFLQKNRKH----P 75
Cdd:cd22211      1 EAALLAWINTFPLSSPVESLDDLSDGVVLAEILSQIdpsYFDSEWLESRDSSDNwvlklNNLKKLYRSLSKYYREvlgqQ 80

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1958645968   76 SSTQCLVSVQKVME-GSEMELAKMVMLFLYHSTMSSRNPRD---WEQFEYGVQAELAVILKFMLD 136
Cdd:cd22211     81 LSDLPLPDLSAIARdGDEEEIVKLLELVLGAAVQCENKEEYiarIQQLDESTQAELMLIIQEVLE 145
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1115-1679 2.90e-12

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 72.41  E-value: 2.90e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1115 EVEALRAEISKLERQWQQQQQQVEGLTHSLESERACRAEQDKALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQ 1194
Cdd:TIGR02169  295 KIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELE 374

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1195 DHSKAEEEWKAQVargqqeaerkssliSSLEEEVSILNRqvlekegESKELKRLVVAESEKSQKLEERLRLLQVETASSS 1274
Cdd:TIGR02169  375 EVDKEFAETRDEL--------------KDYREKLEKLKR-------EINELKRELDRLQEELQRLSEELADLNAAIAGIE 433

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1275 ARAAErssaLREEVQSLREEVEKQRvvsenlrqelasqaERAEESGQELKAWQEKFFQKEQALSALQLEHTSTQALVSEL 1354
Cdd:TIGR02169  434 AKINE----LEEEKEDKALEIKKQE--------------WKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEA 495

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1355 LPAKhlcqQLQAEQAAAEKRFREEIEQSKQAAGGLQAELMRAQR------ELGELGSLRQKIVEQE----RAAQQLRAEK 1424
Cdd:TIGR02169  496 EAQA----RASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGEryataiEVAAGNRLNNVVVEDDavakEAIELLKRRK 571

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1425 ASYAEQLSMLKKAHGLLaeENRGLGERANLGRQFLEVELDQAREK----------YVQELAAVR---------------- 1478
Cdd:TIGR02169  572 AGRATFLPLNKMRDERR--DLSILSEDGVIGFAVDLVEFDPKYEPafkyvfgdtlVVEDIEAARrlmgkyrmvtlegelf 649

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1479 -------------TDAETHLAEMRQEAQSTSRELEVMTAKYESAKVKVLEERQRFQEERQKL---TAQVEELNKKLTESE 1542
Cdd:TIGR02169  650 eksgamtggsrapRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELsdaSRKIGEIEKEIEQLE 729

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1543 QASRVQQQKLKAFQAQGGESQQEVQCLQTQLSELQAQLSQKEQAAEHYKLQMEKAKTH------------YDAKKQQNQE 1610
Cdd:TIGR02169  730 QEEEKLKERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARlshsripeiqaeLSKLEEEVSR 809

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1958645968 1611 LREQLQDLEQ----LQKDNKELRSETERLGRELQQAGLKTKEAEQACRHLTAQVRSLEAQVAHADQQLRDLGK 1679
Cdd:TIGR02169  810 IEARLREIEQklnrLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLES 882
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1286-1617 7.46e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 71.12  E-value: 7.46e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1286 EEVQSLREEVEKQRvvsenlrQELASQAERAEEsGQELKAwQEKFFQKEQALSALQLEHTSTQALVSELLPAKHLCQQLQ 1365
Cdd:COG1196    189 ERLEDILGELERQL-------EPLERQAEKAER-YRELKE-ELKELEAELLLLKLRELEAELEELEAELEELEAELEELE 259

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1366 AEQAAAekrfREEIEQSKQAAGGLQAELMRAQRELGELGS----LRQKIVEQERAAQQLRAEKASYAEQLSMLKKAHGLL 1441
Cdd:COG1196    260 AELAEL----EAELEELRLELEELELELEEAQAEEYELLAelarLEQDIARLEERRRELEERLEELEEELAELEEELEEL 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1442 AEENrglgERANLGRQFLEVELDQAREKYVQELAAVRTDAETHLAEMRQEAQSTSRELEVMTAKYESAK--VKVLEERQR 1519
Cdd:COG1196    336 EEEL----EELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAqlEELEEAEEA 411

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1520 FQEERQKLTAQVEELNKKLTESEQASRVQQQKLKAFQAQGGESQQEVQCLQTQLSELQAQLSQKEQAAEHYKLQMEKAKT 1599
Cdd:COG1196    412 LLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAA 491

                          330
                   ....*....|....*...
gi 1958645968 1600 HYDAKKQQNQELREQLQD 1617
Cdd:COG1196    492 RLLLLLEAEADYEGFLEG 509
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
243-738 1.16e-11

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 70.45  E-value: 1.16e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  243 TEKDAQIAMMQQRIDHlALLNEKQAASPQEPSELEEL----------RGKNESLTVRLHETLKQCQNLKTEKNQMDRKIS 312
Cdd:PRK02224   190 DQLKAQIEEKEEKDLH-ERLNGLESELAELDEEIERYeeqreqaretRDEADEVLEEHEERREELETLEAEIEDLRETIA 268

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  313 QLSEENGDLSFKVREFANHLQQLQGAFNDL----------IEEHSKASQEWAEKQAHLESELSTALQDKKCLEEKSEILQ 382
Cdd:PRK02224   269 ETEREREELAEEVRDLRERLEELEEERDDLlaeaglddadAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAESLR 348

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  383 EKISQLEDRAAQLQGSPAPEKGEVLGDALQLDTLKQEAAKLATDNTELQARVETLECERGKQEAQLLAERGHFEEEKRQL 462
Cdd:PRK02224   349 EDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELRERE 428

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  463 ASLVADLQSSVSNLSQAKEELQQ--------------------ASQAQGAQLTAQLASLTALNATLQQQDQELTSLKEQA 522
Cdd:PRK02224   429 AELEATLRTARERVEEAEALLEAgkcpecgqpvegsphvetieEDRERVEELEAELEDLEEEVEEVEERLERAEDLVEAE 508

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  523 K-----KEQAQMLQ--------TLQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQeaarQDHAQQLATIVEAREas 589
Cdd:PRK02224   509 DrierlEERREDLEeliaerreTIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEA----EEAREEVAELNSKLA-- 582

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  590 vrERDAARQQLETLEkEKDAKLESLQQQLQASNEARDTAQTSVTQAQREKAELSQKIGELH-----ACIEAAHQEQRQAQ 664
Cdd:PRK02224   583 --ELKERIESLERIR-TLLAAIADAEDEIERLREKREALAELNDERRERLAEKRERKRELEaefdeARIEEAREDKERAE 659

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1958645968  665 AHVTELEAQLkaeQQKATEREKVVQEKVQLQEQLQALEEtLKIVRGSLeEEKCRAADALKEQQRHATEMEAETR 738
Cdd:PRK02224   660 EYLEQVEEKL---DELREERDDLQAEIGAVENELEELEE-LRERREAL-ENRVEALEALYDEAEELESMYGDLR 728
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 374-771 1.48e-11

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 70.09  E-value: 1.48e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  374 LEEKSEI--LQEKISQLEDRAAQLQgspapekgevlgdaLQLDTLKQEAAKLATDNTELQARVETLECERGKQEAQLLAe 451
Cdd:TIGR02168  673 LERRREIeeLEEKIEELEEKIAELE--------------KALAELRKELEELEEELEQLRKELEELSRQISALRKDLAR- 737

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  452 rghFEEEKRQLASLVADLQSSVSNLSQAKEELQQASQAQGAQLTAQLASLTALNATLQQQDQELTSLKEQAKKEQAQmlq 531
Cdd:TIGR02168  738 ---LEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAE--- 811

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  532 tLQEQEQAAQGLRQQVEQLSSSLKLKEQQLeeaakeqeaarQDHAQQLATIVEAREASVRERDAARQQLETLEKEkdakL 611
Cdd:TIGR02168  812 -LTLLNEEAANLRERLESLERRIAATERRL-----------EDLEEQIEELSEDIESLAAEIEELEELIEELESE----L 875

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  612 ESLQQQLQASNEARDTAQTSVTQAQREKAELSQKIGELHACIEAAHQEQRQAQAHVTELEAQLKAEQQKATER-----EK 686
Cdd:TIGR02168  876 EALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEysltlEE 955

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  687 VVQEKVQLQEQLQALEETLKIVRGSLEEEKCRAADALKEQQrhatemEAETRHlmeqreqeqkelEQEKAERKGLEARLQ 766
Cdd:TIGR02168  956 AEALENKIEDDEEEARRRLKRLENKIKELGPVNLAAIEEYE------ELKERY------------DFLTAQKEDLTEAKE 1017


                   ....*
gi 1958645968  767 QLEEA 771
Cdd:TIGR02168 1018 TLEEA 1022
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1174-1706 4.10e-11

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 68.79  E-value: 4.10e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1174 HNQAASASAQRE-LQALRAKAQDHSKAEEEwkaqvaRGQQEAERKSSLISSLEEEVSILNRQVLEKEGESKELKRLVVAE 1252
Cdd:COG4913    241 HEALEDAREQIElLEPIRELAERYAAARER------LAELEYLRAALRLWFAQRRLELLEAELEELRAELARLEAELERL 314

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1253 SEKSQKLEERLRLLQVETASSSARAAERssaLREEVQSLREEVEKQRVVSENLRQELASQAERAEESGQELKAWQEKFfq 1332
Cdd:COG4913    315 EARLDALREELDELEAQIRGNGGDRLEQ---LEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEA-- 389

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1333 kEQALSALQLEHTSTQALVSELLPAKHlcqqlqaEQAAAEKRFREEIEQSKQAAGGLQAELMRAQRELGE---------- 1402
Cdd:COG4913    390 -AALLEALEEELEALEEALAEAEAALR-------DLRRELRELEAEIASLERRKSNIPARLLALRDALAEalgldeaelp 461

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1403 ----------------------LGSLRQKI-VEQERAAQQLRaekasYAEQLSMLKKAHGLLAEENRGLGERANLGRQFL 1459
Cdd:COG4913    462 fvgelievrpeeerwrgaiervLGGFALTLlVPPEHYAAALR-----WVNRLHLRGRLVYERVRTGLPDPERPRLDPDSL 536

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1460 ----EVELDQAREkYVQELAAVRTDAE--THLAEMRQEAQ--------STSRELEVMTAKYESAKVKVL-----EERQRF 1520
Cdd:COG4913    537 agklDFKPHPFRA-WLEAELGRRFDYVcvDSPEELRRHPRaitragqvKGNGTRHEKDDRRRIRSRYVLgfdnrAKLAAL 615

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1521 QEERQKLTAQVEELNKKLTESEQASRVQQQKLKAFQ--AQGGESQQEVQCLQTQLSELQAQ----------LSQKEQAAE 1588
Cdd:COG4913    616 EAELAELEEELAEAEERLEALEAELDALQERREALQrlAEYSWDEIDVASAEREIAELEAElerldassddLAALEEQLE 695

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1589 HYKLQMEKAKTHYDAKKQQNQELREQLQDLEQLQKDNKELRSETERLGRELQQAGLKTKEAEQACRHLTAQVR-SLEAQV 1667
Cdd:COG4913    696 ELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGDAVERELReNLEERI 775

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|
gi 1958645968 1668 AHADQQLRDL-GKFQVATDALKSREPQVKPQLDLSIDSLD 1706
Cdd:COG4913    776 DALRARLNRAeEELERAMRAFNREWPAETADLDADLESLP 815
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1464-1677 4.30e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 68.42  E-value: 4.30e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1464 DQAREKYVQELAAVRTDAETHLAEMRQEAQSTSRELEVMTAKYESAKVKVLEERQRFQEERQKLT---AQVEELNKKLTE 1540
Cdd:COG1196    220 EELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEeaqAEEYELLAELAR 299

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1541 SEQASRVQQQKLKAFQAQGGESQQEVQCLQTQLSELQAQLSQKEQAAEHYKLQMEKAKthyDAKKQQNQELREQLQDLEQ 1620
Cdd:COG1196    300 LEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAE---AELAEAEEALLEAEAELAE 376

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1958645968 1621 LQKDNKELRSETERLGRELQQAGLKTKEAEQACRHLTAQVRSLEAQVAHADQQLRDL 1677
Cdd:COG1196    377 AEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAEL 433
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 591-1546 6.21e-11

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 68.17  E-value: 6.21e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  591 RERDAARQQLETLEK---EKDAKLESLQQQLQAsneardtaqtsvTQAQREKAELSQKIgelhacieaahqeqrqaQAHV 667
Cdd:TIGR02169  170 RKKEKALEELEEVEEnieRLDLIIDEKRQQLER------------LRREREKAERYQAL-----------------LKEK 220

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  668 TELEAQLKAEQQKATEREKVvqekvQLQEQLQALEEtlkivrgSLEEEKCRAADALKEQQRHATEMEAETRHLMEQREQE 747
Cdd:TIGR02169  221 REYEGYELLKEKEALERQKE-----AIERQLASLEE-------ELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEE 288

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  748 QKELEQEKAERKGLEARLQQLEEAHQAETEALRHELAGATAAQHGAESEREQLLREVESWQKRVEARQQEearygamfqe 827
Cdd:TIGR02169  289 QLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEE---------- 358

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  828 qlmalkgehgkigqeeqkeageihgegqtgqqqsqLAQLHACLAKALQQVQEKEARAQKLLDDLSALREKMAATNKEVAC 907
Cdd:TIGR02169  359 -----------------------------------YAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINE 403

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  908 LKALVLKAGEQQAAASHELKEpprAGNQESDWEEEQArplgSTQAALKAVQREAEQMGGELERLraalmqsqgqqQEVRG 987
Cdd:TIGR02169  404 LKRELDRLQEELQRLSEELAD---LNAAIAGIEAKIN----ELEEEKEDKALEIKKQEWKLEQL-----------AADLS 465

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  988 QQEREVARLTQERGQAQADLAQEKAAKAELEMRLQNTLNEQRvEFAALQEALTHAMTEKEGKDQELAKLREQ-----EAA 1062
Cdd:TIGR02169  466 KYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVR-GGRAVEEVLKASIQGVHGTVAQLGSVGERyataiEVA 544

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1063 QISELKAL----QQTLEELKKKEKEHPTGGAR----GEDASGDGPGSQLHTPGkteapgpeVEALRAEISKLERQWQQQQ 1134
Cdd:TIGR02169  545 AGNRLNNVvvedDAVAKEAIELLKRRKAGRATflplNKMRDERRDLSILSEDG--------VIGFAVDLVEFDPKYEPAF 616

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1135 QQVEGLTHSLESERACRAEQDKA-LETLQGQLEEKARELGHNQAASASAQRELQALRAKAQDHSKAEEEWKAQVARGQQE 1213
Cdd:TIGR02169  617 KYVFGDTLVVEDIEAARRLMGKYrMVTLEGELFEKSGAMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSE 696

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1214 AERKSSLISSLEEEVSILNRQVLEKEGESKELKRLVVAESEKSQKLEERLRLLQVETA---SSSARAAERSSALREEVQS 1290
Cdd:TIGR02169  697 LRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIEnvkSELKELEARIEELEEDLHK 776

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1291 LREEVEK-QRVVSENLRQELASQAERAEEsgqELKAWQEKFFQKEQALSALQLEHTSTQALVSELLpakhlcqQLQAEQA 1369
Cdd:TIGR02169  777 LEEALNDlEARLSHSRIPEIQAELSKLEE---EVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQ-------EQRIDLK 846

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1370 AAEKRFREEIEQSKQAAGGLQAELMRAQRELGELGS-----------LRQKIVEQERAAQQLRAEKASYAEQLSMLKKAH 1438
Cdd:TIGR02169  847 EQIKSIEKEIENLNGKKEELEEELEELEAALRDLESrlgdlkkerdeLEAQLRELERKIEELEAQIEKKRKRLSELKAKL 926

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1439 GLLAEENRGLGERANLGRQFLEVELDqarekyvqelaavrtdaETHLAEMRQEAQSTSRELEVMTAKYESAKVKVLEERQ 1518
Cdd:TIGR02169  927 EALEEELSEIEDPKGEDEEIPEEELS-----------------LEDVQAELQRVEEEIRALEPVNMLAIQEYEEVLKRLD 989

                          970       980
                   ....*....|....*....|....*...
gi 1958645968 1519 RFQEERQKLTAQVEELNKKLTESEQASR 1546
Cdd:TIGR02169  990 ELKEKRAKLEEERKAILERIEEYEKKKR 1017
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 275-908 1.56e-10

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 66.63  E-value: 1.56e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  275 ELEELRGKNESLTVRLHETLKQCQNLKTEKNQMDRKISQLSEENGDLSFKVREFANHLQQLQGAFNDLIEEHSKASQEWA 354
Cdd:TIGR02169  288 EQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELE 367

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  355 EKQAHLEsELSTALQDkkcLEEKSEILQEKISQLEDRAAQLQGSPAPEKGEVLGDALQLDTLKQEAAKLATDNTELQARV 434
Cdd:TIGR02169  368 DLRAELE-EVDKEFAE---TRDELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEK 443

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  435 ETLECERGKQEAQLLAERGHFEEEKRQLASLVADLQSSVSNLSQAKEELQQASQAQGAQLTAQL---ASLTALNATLQ-- 509
Cdd:TIGR02169  444 EDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRggrAVEEVLKASIQgv 523

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  510 -QQDQELTSLKEQAKKE---------QAQMLQTLQEQEQAAQGLRQqvEQLSSSLKLKEQQLEEAAKEQEAARQDHAQQL 579
Cdd:TIGR02169  524 hGTVAQLGSVGERYATAievaagnrlNNVVVEDDAVAKEAIELLKR--RKAGRATFLPLNKMRDERRDLSILSEDGVIGF 601

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  580 AT---------------------IVEAREA---------------------------SVRERDAARQQLETLEKEKD--A 609
Cdd:TIGR02169  602 AVdlvefdpkyepafkyvfgdtlVVEDIEAarrlmgkyrmvtlegelfeksgamtggSRAPRGGILFSRSEPAELQRlrE 681

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  610 KLESLQQQLQASNEARDTAQTSVTQAQREKAELSQKIGELHACIEAAHQEQRQAQAHVTELEAQLKAEQQkatEREKVVQ 689
Cdd:TIGR02169  682 RLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQ---EIENVKS 758

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  690 EKVQLQEQLQALEETLKIVRGSLEEEKCRAADA-LKEQQRHATEMEaetrhlmeqreqeqkeleqekAERKGLEARLQQL 768
Cdd:TIGR02169  759 ELKELEARIEELEEDLHKLEEALNDLEARLSHSrIPEIQAELSKLE---------------------EEVSRIEARLREI 817

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  769 EEAHQAET---EALRHELAGATAAQHGAESEREQLLREVESWQKRVEARQQEEARYgamfQEQLMALKGEHGKIgQEEQK 845
Cdd:TIGR02169  818 EQKLNRLTlekEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEEL----EAALRDLESRLGDL-KKERD 892

                          650       660       670       680       690       700
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1958645968  846 EAgeihgEGQTGQQQSQLAQLHACLAKALQQVQEKEARAQKLLDDLSALREKMAATNKEVACL 908
Cdd:TIGR02169  893 EL-----EAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEE 950
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
577-1072 1.99e-10

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 66.48  E-value: 1.99e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  577 QQLATIVEAREASVRerdaARQQLETLE--KEKDAKLESLQQQLQASNEARDT-----AQTSVTQAQREKAELSQKIGEL 649
Cdd:COG4913    232 EHFDDLERAHEALED----AREQIELLEpiRELAERYAAARERLAELEYLRAAlrlwfAQRRLELLEAELEELRAELARL 307

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  650 HACIEAAHQEQRQAQAHVTELEAQL-----KAEQQKATEREKVVQEKVQLQEQLQALEETLKIVRGSLEEEKCRAADALK 724
Cdd:COG4913    308 EAELERLEARLDALREELDELEAQIrgnggDRLEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRA 387

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  725 EQQRHATEMEAETRHLMEQREQEQKELEQEKAERKGLEARLQQLEEAHQ---AETEALRHELAGATAAqhgaeSERE--- 798
Cdd:COG4913    388 EAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSnipARLLALRDALAEALGL-----DEAElpf 462

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  799 -----QLLREVESWQKRVEA--RQQE-----EARYGAMFQEQLMALKGEHGKIGQEEQKEAGEIHGEGQTGQQ------- 859
Cdd:COG4913    463 vgeliEVRPEEERWRGAIERvlGGFAltllvPPEHYAAALRWVNRLHLRGRLVYERVRTGLPDPERPRLDPDSlagkldf 542

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  860 ---------QSQLAQL--HACL--AKALQ----------QVQEKEARAQKllDDLSALR----------EKMAATNKEVA 906
Cdd:COG4913    543 kphpfrawlEAELGRRfdYVCVdsPEELRrhpraitragQVKGNGTRHEK--DDRRRIRsryvlgfdnrAKLAALEAELA 620

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  907 CLKALVLKAGEQQAAASHELKEPPRAGN-----QESDWEEEQARPLGSTQAALKAVQREAEQMGGELERLRAALMQSQGQ 981
Cdd:COG4913    621 ELEEELAEAEERLEALEAELDALQERREalqrlAEYSWDEIDVASAEREIAELEAELERLDASSDDLAALEEQLEELEAE 700

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  982 QQEVrgqqEREVARLTQERGQAQADLAQEKAAKAELEMRLQNTLNEQRVE-FAALQEALthamtEKEGKDQELAKLREQE 1060
Cdd:COG4913    701 LEEL----EEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLElRALLEERF-----AAALGDAVERELRENL 771

                          570
                   ....*....|..
gi 1958645968 1061 AAQISELKALQQ 1072
Cdd:COG4913    772 EERIDALRARLN 783
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 304-879 5.90e-10

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 64.75  E-value: 5.90e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  304 KNQMDRKISQLSeengDLSFKVREFANHLQQLQGAFNDLIEEhskasqewAEKQAHL-ESELSTALQDKKCLEEKS---- 378
Cdd:pfam15921  309 RNQNSMYMRQLS----DLESTVSQLRSELREAKRMYEDKIEE--------LEKQLVLaNSELTEARTERDQFSQESgnld 376

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  379 EILQEKISQLEDRAAQLQGSPAPEK---GEVLGDALQLDTLKQEAAKLATDNTELQARVETLECE-RGKQEAQLLAERGH 454
Cdd:pfam15921  377 DQLQKLLADLHKREKELSLEKEQNKrlwDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSEcQGQMERQMAAIQGK 456

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  455 fEEEKRQLASLVADLQSSVSNLSQAKEELqqasqaqgaqltaqlaslTALNATLQQQDQELTSLKeqakkeqaqmlQTLQ 534
Cdd:pfam15921  457 -NESLEKVSSLTAQLESTKEMLRKVVEEL------------------TAKKMTLESSERTVSDLT-----------ASLQ 506

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  535 EQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEqeaarQDHAQQLATiveareasvrERDAARQQLetleKEKDAKLESL 614
Cdd:pfam15921  507 EKERAIEATNAEITKLRSRVDLKLQELQHLKNE-----GDHLRNVQT----------ECEALKLQM----AEKDKVIEIL 567

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  615 QQQLQASNEARDTAQTSVTQAQREKAELSQKIG-------ELHACIEAAHQEQRQAQAHVTELEAQLKAEQQKATEREKV 687
Cdd:pfam15921  568 RQQIENMTQLVGQHGRTAGAMQVEKAQLEKEINdrrlelqEFKILKDKKDAKIRELEARVSDLELEKVKLVNAGSERLRA 647

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  688 VQEKVQLQEQLQALEETLKIVRGSLEEEkcraADALKEQQRHAT-EMEAETRHLmeqreqeqkeleqeKAERKGLEARLQ 766
Cdd:pfam15921  648 VKDIKQERDQLLNEVKTSRNELNSLSED----YEVLKRNFRNKSeEMETTTNKL--------------KMQLKSAQSELE 709

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  767 QLEEAHQAETEALRHELAGATAAQHGAESEREQlLREVESWQKRVEARQQEEARYGAMFQEQLMALKGEHGKIGQEEQKE 846
Cdd:pfam15921  710 QTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQ-IDALQSKIQFLEEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKM 788

                          570       580       590
                   ....*....|....*....|....*....|....
gi 1958645968  847 AGEIHG-EGQTGQQQSQLAQLHACLAKALQQVQE 879
Cdd:pfam15921  789 AGELEVlRSQERRLKEKVANMEVALDKASLQFAE 822
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 874-1636 6.55e-10

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 64.70  E-value: 6.55e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  874 LQQVQEKEARAQKLLDDLSALREKMAaTNKEVAcLKALVLKAGEQQAAASHELKEPPRAGNQESDWEEEqarpLGSTQAA 953
Cdd:TIGR02169  179 LEEVEENIERLDLIIDEKRQQLERLR-REREKA-ERYQALLKEKREYEGYELLKEKEALERQKEAIERQ----LASLEEE 252

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  954 LKAVQREAEQMGGELERLRAALMQsqgQQQEVRGQQEREVARLTQERGQAQADLAQEKAAKAELEMRLQNTLNEQRVEFA 1033
Cdd:TIGR02169  253 LEKLTEEISELEKRLEEIEQLLEE---LNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEA 329

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1034 ALQEALThamtEKEGKDQELAKLREQEAAQISELKALQQTLEELKKKEKEHPTGGARGEDASgdgpgSQLHTpgKTEAPG 1113
Cdd:TIGR02169  330 EIDKLLA----EIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDEL-----KDYRE--KLEKLK 398

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1114 PEVEALRAEISKLERQWQQQQQQVEGLTHSLESERACRAEQDKALETLQGQLEEKARELGHNQAASASAQRELQALRAKA 1193
Cdd:TIGR02169  399 REINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLKEEY 478

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1194 QDH----SKAEEEWKAQVARGQQEAERK---------------------SSLISSLEE-----EVSILNRQ---VLEKEG 1240
Cdd:TIGR02169  479 DRVekelSKLQRELAEAEAQARASEERVrggraveevlkasiqgvhgtvAQLGSVGERyataiEVAAGNRLnnvVVEDDA 558

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1241 ESKE-----------------LKRLVVAESEKSQKLEE-----RLRLLQVETASSSA-RAAERSSALREEVQSLREEVEK 1297
Cdd:TIGR02169  559 VAKEaiellkrrkagratflpLNKMRDERRDLSILSEDgvigfAVDLVEFDPKYEPAfKYVFGDTLVVEDIEAARRLMGK 638

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1298 QRVVS---------------ENLRQELASQAERAEESGQELKAWQEKFfqkEQALSALQLEHTSTQALVSELLPAKHLCQ 1362
Cdd:TIGR02169  639 YRMVTlegelfeksgamtggSRAPRGGILFSRSEPAELQRLRERLEGL---KRELSSLQSELRRIENRLDELSQELSDAS 715

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1363 QLQAEQAAAEKRFREEIEQSKQaaggLQAELMRaqrelgELGSLRQKIVEQERAAQQLRAEKASYAEQLSMLKKAhglla 1442
Cdd:TIGR02169  716 RKIGEIEKEIEQLEQEEEKLKE----RLEELEE------DLSSLEQEIENVKSELKELEARIEELEEDLHKLEEA----- 780

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1443 eenrglgeRANLGRQFLEVELDQAREKYvQELAAVRTDAETHLAEMRQEAQSTSRELEvmtakYESAKVKVLEERQRFQE 1522
Cdd:TIGR02169  781 --------LNDLEARLSHSRIPEIQAEL-SKLEEEVSRIEARLREIEQKLNRLTLEKE-----YLEKEIQELQEQRIDLK 846

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1523 ERQK-LTAQVEELNKKLTESEQasrvqqqKLKAFQAQGGESQQEVQCLQTQLSELQAQLSQKEQAAEHYKLQMEKAKTHY 1601
Cdd:TIGR02169  847 EQIKsIEKEIENLNGKKEELEE-------ELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRL 919

                          810       820       830
                   ....*....|....*....|....*....|....*
gi 1958645968 1602 DAKKQQNQELREQLQDLEQLQKDNKELRSETERLG 1636
Cdd:TIGR02169  920 SELKAKLEALEEELSEIEDPKGEDEEIPEEELSLE 954
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1221-1687 9.91e-10

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 64.17  E-value: 9.91e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1221 ISSLEEEVSILNRQV--LEKEGESKELKRLVVAESEKSQKLEERLRLLQVETASSSARAAERssALREEVQSLREEVEKQ 1298
Cdd:COG4913    237 LERAHEALEDAREQIelLEPIRELAERYAAARERLAELEYLRAALRLWFAQRRLELLEAELE--ELRAELARLEAELERL 314

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1299 RVVSENLRQELAS-QAERAEESGQELKAWQEKFFQKEQALSALQLEHTSTQALVSELlpakhlcqqlQAEQAAAEKRFRE 1377
Cdd:COG4913    315 EARLDALREELDElEAQIRGNGGDRLEQLEREIERLERELEERERRRARLEALLAAL----------GLPLPASAEEFAA 384

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1378 EIEQSKQAAGGLQAELMRAQRELGELgslRQKIVEQERAAQQLRAEKAS-----------YAEQLSMLKKAHGLLAEENR 1446
Cdd:COG4913    385 LRAEAAALLEALEEELEALEEALAEA---EAALRDLRRELRELEAEIASlerrksniparLLALRDALAEALGLDEAELP 461

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1447 GLGEranlgrqFLEVELDQAR--------------------EKYVQELAAV-RTDAETHL------------AEMRQEAQ 1493
Cdd:COG4913    462 FVGE-------LIEVRPEEERwrgaiervlggfaltllvppEHYAAALRWVnRLHLRGRLvyervrtglpdpERPRLDPD 534

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1494 STSRELEVMTAKYESAKVKVLEER---------QRFQEERQKLTA--QVEElNKKLTESEQASRVQQQ---------KLK 1553
Cdd:COG4913    535 SLAGKLDFKPHPFRAWLEAELGRRfdyvcvdspEELRRHPRAITRagQVKG-NGTRHEKDDRRRIRSRyvlgfdnraKLA 613

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1554 AFQAQGGESQQEVQCLQTQLSELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQ--ELREQLQDLEQLQKDNKELRSE 1631
Cdd:COG4913    614 ALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEIDVASAEREiaELEAELERLDASSDDLAALEEQ 693

                          490       500       510       520       530
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1958645968 1632 TERLGRELQQAGLKTKEAEQACRHLTAQVRSLEAQVAHADQQLRDLGKFQVATDAL 1687
Cdd:COG4913    694 LEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRA 749
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1459-1706 1.15e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 63.80  E-value: 1.15e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1459 LEVELDQAREKyVQELAAVRTDAETHLAEMRQEAQSTSRELEVMTAKY---ESAKVKVLEERQRFQEERQKLTAQVEELN 1535
Cdd:COG1196    244 LEAELEELEAE-LEELEAELAELEAELEELRLELEELELELEEAQAEEyelLAELARLEQDIARLEERRRELEERLEELE 322

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1536 KKLTESEQASRVQQQKLKAFQAQGGESQQEVQCLQTQLSELQAQLSQKEQAAEhyklqmEKAKTHYDAKKQQNQELREQL 1615
Cdd:COG1196    323 EELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELA------EAEEELEELAEELLEALRAAA 396

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1616 QDLEQLQKDNKELRSETERLGRELQQAGLKTKEAEQACRHLTAQVRSLEAQVAHADQQLRDLGKFQVATDALKSREPQVK 1695
Cdd:COG1196    397 ELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLE 476

                          250
                   ....*....|.
gi 1958645968 1696 PQLDLSIDSLD 1706
Cdd:COG1196    477 AALAELLEELA 487
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 275-1021 2.42e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 62.78  E-value: 2.42e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  275 ELEELRGKNESLTVRLHETLKQCQNLKTEKNQmdrkisqlSEENGDLSFKVREFANHLqqLQGAFNDLIEEHSKASQEWA 354
Cdd:TIGR02169  178 ELEEVEENIERLDLIIDEKRQQLERLRREREK--------AERYQALLKEKREYEGYE--LLKEKEALERQKEAIERQLA 247

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  355 EKQAHLE---SELSTALQDKKCLEEKSEILQEKISQL-EDRAAQLQGSPAPEKGEVLGDALQLDTLKQEAaklatdnTEL 430
Cdd:TIGR02169  248 SLEEELEkltEEISELEKRLEEIEQLLEELNKKIKDLgEEEQLRVKEKIGELEAEIASLERSIAEKEREL-------EDA 320

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  431 QARVETLECERGKQEAQLLAERGHFEEEKRQLASLVADLQSSvsnlsqaKEELqqasqaqgAQLTAQLASLTALNATLQQ 510
Cdd:TIGR02169  321 EERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAEL-------KEEL--------EDLRAELEEVDKEFAETRD 385

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  511 QDQELTSLKEQAKKEQAQMLQTLQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEAARQDHA---QQLATIVEARE 587
Cdd:TIGR02169  386 ELKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKkqeWKLEQLAADLS 465

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  588 ASVRERDAARQQLETLEKEkdakLESLQQQLQASNEARDTAQTSVTQAQREKAELSQKIGELHACIEaahQEQRQAQAHV 667
Cdd:TIGR02169  466 KYEQELYDLKEEYDRVEKE----LSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVA---QLGSVGERYA 538

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  668 TELEAQLKAEQQK-ATEREKVVQEKVQLQEQLQALEETL----KIVRGSLEEEKCR-------AADALKEQQRHAT---- 731
Cdd:TIGR02169  539 TAIEVAAGNRLNNvVVEDDAVAKEAIELLKRRKAGRATFlplnKMRDERRDLSILSedgvigfAVDLVEFDPKYEPafky 618

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  732 ---------EMEAETRHL------------------MEQREQEQKELEQEKAERKGLEARLQQLEEAHQAETEALRHELA 784
Cdd:TIGR02169  619 vfgdtlvveDIEAARRLMgkyrmvtlegelfeksgaMTGGSRAPRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELR 698

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  785 GATAAQHGAESEREQLLREVESWQKRVEARQQEEARygamFQEQLMALKGEHGKIGQE-EQKEAGEIHGEGQTGQQQSQL 863
Cdd:TIGR02169  699 RIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEK----LKERLEELEEDLSSLEQEiENVKSELKELEARIEELEEDL 774

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  864 AQLHACLAK-----ALQQVQEKEARAQKLLDDLSALREKMAATNKEvacLKALVLKAGEQQAAASHELKEPPRAGNQESD 938
Cdd:TIGR02169  775 HKLEEALNDlearlSHSRIPEIQAELSKLEEEVSRIEARLREIEQK---LNRLTLEKEYLEKEIQELQEQRIDLKEQIKS 851

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  939 WEEEQArplgSTQAALKAVQREAEQMGGELERLRAALMQSQGQQQEVR---GQQEREVARLTQERGQAQADLAQEKAAKA 1015
Cdd:TIGR02169  852 IEKEIE----NLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEaqlRELERKIEELEAQIEKKRKRLSELKAKLE 927


                   ....*.
gi 1958645968 1016 ELEMRL 1021
Cdd:TIGR02169  928 ALEEEL 933
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1156-1689 4.93e-09

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 61.85  E-value: 4.93e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1156 KALETLQGQLE--EKARELGHNQAASASAQRELQALRA---------KAQDHSKAEEEWKAQVARGQQEAERKSSLISSL 1224
Cdd:COG4913    242 EALEDAREQIEllEPIRELAERYAAARERLAELEYLRAalrlwfaqrRLELLEAELEELRAELARLEAELERLEARLDAL 321

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1225 EEEVSILNRQVLEKEGESKElkrlvvaeseksqKLEERLRLLQVETAsssaRAAERSSALREEVQSLREEVEKQRVVSEN 1304
Cdd:COG4913    322 REELDELEAQIRGNGGDRLE-------------QLEREIERLERELE----ERERRRARLEALLAALGLPLPASAEEFAA 384

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1305 LRQELASQAERAEEsgqELKAWQEKFFQKEQALSALQLEHTSTQALVSEL------LPAKHLcqqlqaeqaaaekRFREE 1378
Cdd:COG4913    385 LRAEAAALLEALEE---ELEALEEALAEAEAALRDLRRELRELEAEIASLerrksnIPARLL-------------ALRDA 448

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1379 IEQskqAAGGLQAEL--------MRAQREL------GELGSLRQKI-VEQERAAQQLRaekasYAEQLSMLKKAHGLLAE 1443
Cdd:COG4913    449 LAE---ALGLDEAELpfvgelieVRPEEERwrgaieRVLGGFALTLlVPPEHYAAALR-----WVNRLHLRGRLVYERVR 520

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1444 ENRGLGERANLGRQFL----EVELDQAREkYVQELAAVRTDAE--THLAEMRQEAQ--------STSRELEVMTAKYESA 1509
Cdd:COG4913    521 TGLPDPERPRLDPDSLagklDFKPHPFRA-WLEAELGRRFDYVcvDSPEELRRHPRaitragqvKGNGTRHEKDDRRRIR 599

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1510 KVKVL-----EERQRFQEERQKLTAQVEELNKKLTESEQASRVQQQKLKAFQ--AQGGESQQEVQCLQTQLSELQAQLSQ 1582
Cdd:COG4913    600 SRYVLgfdnrAKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQrlAEYSWDEIDVASAEREIAELEAELER 679

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1583 KEQAaehyklqmekakthydakkqqNQELREQLQDLEQLQKDNKELRSETERLGRELQQAGLKTKEAEQACRHLTAQVRS 1662
Cdd:COG4913    680 LDAS---------------------SDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEA 738

                          570       580       590
                   ....*....|....*....|....*....|..
gi 1958645968 1663 LE-----AQVAHADQQLRDLGKFQVATDALKS 1689
Cdd:COG4913    739 AEdlarlELRALLEERFAAALGDAVERELREN 770
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1373-1681 5.80e-09

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 61.61  E-value: 5.80e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1373 KRFREEIEQSKQAAGGLQAelMRAQRELGELGSLRQKIVEQERAAQQLRAEKASYAEQLSMLKKAHGLLAEEnrglgera 1452
Cdd:TIGR02168  213 ERYKELKAELRELELALLV--LRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEE-------- 282

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1453 nlgrqflEVELDQAREKYVQELAAVRTDAEtHLAEMRQEAQSTSRELEVMTAKYESAKVKVLEERQRFQEERQKLTAQVE 1532
Cdd:TIGR02168  283 -------IEELQKELYALANEISRLEQQKQ-ILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELE 354

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1533 ELNKKLTESEQASRVQQQKLKAFQAQGGESQQEVQCLQTQLSELQAQL----SQKEQAAEHYKLQMEKAKTHydAKKQQN 1608
Cdd:TIGR02168  355 SLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIerleARLERLEDRRERLQQEIEEL--LKKLEE 432

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1958645968 1609 QELREQLQDLEQLQKDNKELRSETERLGRELQQAGLKTKEAEQACRHLTAQVRSLEAQVAHADQQLRDLGKFQ 1681
Cdd:TIGR02168  433 AELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFS 505
PTZ00121 PTZ00121
MAEBL; Provisional
 1142-1652 6.79e-09

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 61.70  E-value: 6.79e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1142 HSLESERACRAEQDKALETLQGQLEEKARElgHNQAASASAQRELQALRAKAQDHSKAEEEWKAQVARGQQEAERKSSLI 1221
Cdd:PTZ00121  1056 HEGKAEAKAHVGQDEGLKPSYKDFDFDAKE--DNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEA 1133

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1222 SSLEEEVSIlnrqvlEKEGESKELKRLVVA-ESEKSQKLEERLRLLQVETASSSARAAERSSAlrEEVQSLRE--EVEKQ 1298
Cdd:PTZ00121  1134 RKAEDARKA------EEARKAEDAKRVEIArKAEDARKAEEARKAEDAKKAEAARKAEEVRKA--EELRKAEDarKAEAA 1205

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1299 RVVSENLRQELASQAERAEESgQELKAWQEKFFQKEQALSALQLEHTSTQALVSELLPAKHlcQQLQAEQAAAEKRFREE 1378
Cdd:PTZ00121  1206 RKAEEERKAEEARKAEDAKKA-EAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHF--ARRQAAIKAEEARKADE 1282

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1379 IEQSKQAAgglQAELMRAQRELGELGSLRQKiVEQERAAQQLRAEKASYAEQLSMLKKAhgllAEENRGLGERAnlgrqf 1458
Cdd:PTZ00121  1283 LKKAEEKK---KADEAKKAEEKKKADEAKKK-AEEAKKADEAKKKAEEAKKKADAAKKK----AEEAKKAAEAA------ 1348

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1459 leveldqarekyvqelaavrtdaethlaemRQEAQSTSRELEVMTAKYESAKVKVLEERQRFQEERQKL--TAQVEELNK 1536
Cdd:PTZ00121  1349 ------------------------------KAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAeeKKKADEAKK 1398

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1537 KLTE----SEQASRVQQQKLKAFQA-QGGESQQEVQCLQTQLSELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQEL 1611
Cdd:PTZ00121  1399 KAEEdkkkADELKKAAAAKKKADEAkKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAKKK 1478

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|.
gi 1958645968 1612 REQLQDLEQLQKDNKELRSETERLgRELQQAGLKTKEAEQA 1652
Cdd:PTZ00121  1479 AEEAKKADEAKKKAEEAKKKADEA-KKAAEAKKKADEAKKA 1518
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 391-1071 1.59e-08

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 59.98  E-value: 1.59e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  391 RAAQLQGSPAPEKGEVLGDALQLDTLKQEAAKLATDNTELQARVETLEcERGKQEAQLLAERGHFEEEKRQ-LASLVADL 469
Cdd:TIGR00618  153 EFAQFLKAKSKEKKELLMNLFPLDQYTQLALMEFAKKKSLHGKAELLT-LRSQLLTLCTPCMPDTYHERKQvLEKELKHL 231

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  470 QSSVSNLSQAKEELQQASQAQGAQLTAQLASLTALNATLQQQDQELTSLKEQAKKEQAQMLQTLQEQEQAAQGLRQQVEQ 549
Cdd:TIGR00618  232 REALQQTQQSHAYLTQKREAQEEQLKKQQLLKQLRARIEELRAQEAVLEETQERINRARKAAPLAAHIKAVTQIEQQAQR 311

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  550 LSSSLKLKE---QQLEEAAKEQEAARQDHAQQLATIVEAREASVRERDAARQQLETLEKEKDAK------------LESL 614
Cdd:TIGR00618  312 IHTELQSKMrsrAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQQHtltqhihtlqqqKTTL 391

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  615 QQQLQASNEARDTAQTSVTQAQREKAE---LSQKIGELHACIEAAHQE---QRQAQAHVTELEAQLKAEQQKATEREKVV 688
Cdd:TIGR00618  392 TQKLQSLCKELDILQREQATIDTRTSAfrdLQGQLAHAKKQQELQQRYaelCAAAITCTAQCEKLEKIHLQESAQSLKER 471

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  689 QEKVQLQEQLQALEETLKIVRGSLEEEKCRAADALKEQQRH-------ATEMEAETRHLMEQREQEQKELEQEKAERKGL 761
Cdd:TIGR00618  472 EQQLQTKEQIHLQETRKKAVVLARLLELQEEPCPLCGSCIHpnparqdIDNPGPLTRRMQRGEQTYAQLETSEEDVYHQL 551

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  762 EARLQQLEEaHQAETEALRHELAGATAAQHGAESEREQLLREVESWQKRVEARQQEEARYGAMFQEQLMALK-------- 833
Cdd:TIGR00618  552 TSERKQRAS-LKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLACEQHALLRKLQpeqdlqdv 630

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  834 -GEHGKIGQEEQKEAGEIHGEGQTGQQQSQ---LAQLHACLAKALQQVQEKEARAQKLLDDLSALREKMAATNKEVACLK 909
Cdd:TIGR00618  631 rLHLQQCSQELALKLTALHALQLTLTQERVrehALSIRVLPKELLASRQLALQKMQSEKEQLTYWKEMLAQCQTLLRELE 710

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  910 ALVLKAGEQQaaashelkeppragnqesdweEEQARPLGSTQAALKAVQREAEQMGGELERLRAALMQSQGQQQEVRGQQ 989
Cdd:TIGR00618  711 THIEEYDREF---------------------NEIENASSSLGSDLAAREDALNQSLKELMHQARTVLKARTEAHFNNNEE 769

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  990 EREVARLTQERGQAQADLAQEKAAKAELEMRLQNTLNEQRVEFAALQEALTHAMTEKEGKDQELAKLREQEAAQISELKA 1069
Cdd:TIGR00618  770 VTAALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQCETLVQEEEQFLSRLEEKSATLGEITH 849


                   ..
gi 1958645968 1070 LQ 1071
Cdd:TIGR00618  850 QL 851
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 454-783 1.59e-08

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 60.24  E-value: 1.59e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  454 HFEEEKRQLASLVADLQSSVSNLSQAKEELqqasQAQGAQLTAQLASLTALNATLQQQDQELTSLKEQAKKEQAQMLQTL 533
Cdd:pfam12128  598 SEEELRERLDKAEEALQSAREKQAAAEEQL----VQANGELEKASREETFARTALKNARLDLRRLFDEKQSEKDKKNKAL 673

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  534 QEQEQAAQGLRQQVEQLSSSLKLKEQQ-LEEAAKEQEAARQDHAQQLATIVEAREASVrerDAARQQLETLEKEKDAKLE 612
Cdd:pfam12128  674 AERKDSANERLNSLEAQLKQLDKKHQAwLEEQKEQKREARTEKQAYWQVVEGALDAQL---ALLKAAIAARRSGAKAELK 750

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  613 SLQQQLQASNEARDTAQTSVTQAQREKAELSQKIGelhaciEAAHQEQRQAQAHVTELEAQLKAEQQKATEREKVVQEKV 692
Cdd:pfam12128  751 ALETWYKRDLASLGVDPDVIAKLKREIRTLERKIE------RIAVRRQEVLRYFDWYQETWLQRRPRLATQLSNIERAIS 824

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  693 QLQEQLQALEETLKIVRGSLEEEKcraaDALKEQQRHATEMEAETRHLMEQREQEQKELEQEKAERKGLE--ARLQQLEE 770
Cdd:pfam12128  825 ELQQQLARLIADTKLRRAKLEMER----KASEKQQVRLSENLRGLRCEMSKLATLKEDANSEQAQGSIGErlAQLEDLKL 900

                          330
                   ....*....|...
gi 1958645968  771 AHQAETEALRHEL 783
Cdd:pfam12128  901 KRDYLSESVKKYV 913
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1116-1609 1.69e-08

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 59.78  E-value: 1.69e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1116 VEALRAEISKLERQWQQQQQQVEGLTHSLESERACRAEQDKALETLQGQLEEKARELghnqaasASAQRELQALRAKAQD 1195
Cdd:COG4717     48 LERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEEL-------EELEAELEELREELEK 120

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1196 HSKAEEEWKAQVARGQQEAErksslISSLEEEVSILNRQVLEKEGESKELKRLVVAESEKSQKLEERLRLLQVETASSSA 1275
Cdd:COG4717    121 LEKLLQLLPLYQELEALEAE-----LAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQ 195

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1276 RAAERSSALREEVQSLREEVEKQRVVSENLRQELASQAERAEESGQELKAWQEKFFQKEQA-LSALQLEHTSTQALVSEL 1354
Cdd:COG4717    196 DLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLLLLIAAaLLALLGLGGSLLSLILTI 275

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1355 LPAKHLCQQLQAEQAAAEKRFREEIEQSKQAAGGLQAelmraqrelgelgslrQKIVEQERAAQQLRAEKASYAEQLSML 1434
Cdd:COG4717    276 AGVLFLVLGLLALLFLLLAREKASLGKEAEELQALPA----------------LEELEEEELEELLAALGLPPDLSPEEL 339

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1435 KKAHGLLAEENRGLGERANLGRQFLEVELDQAREKYVQELAAVRTDAETHLAEMRQEAQSTSRELEVMTAKYESAKVKVL 1514
Cdd:COG4717    340 LELLDRIEELQELLREAEELEEELQLEELEQEIAALLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGELE 419

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1515 EERQRFQEERqkLTAQVEELNKKLTESEQASRVQQQKLKAFQAQGG--ESQQEVQCLQTQLSELQAQLSQKEQAAEHYKL 1592
Cdd:COG4717    420 ELLEALDEEE--LEEELEELEEELEELEEELEELREELAELEAELEqlEEDGELAELLQELEELKAELRELAEEWAALKL 497

                          490
                   ....*....|....*..
gi 1958645968 1593 QMEKAKTHYDAKKQQNQ 1609
Cdd:COG4717    498 ALELLEEAREEYREERL 514
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 300-918 2.95e-08

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 59.47  E-value: 2.95e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  300 LKTEKNQMDRKISQLSEENGDLSFKVREFANHLQQLQGAFNDLIEEHSKASQEWAEKQAHLESELSTALQDKKCLEEKSE 379
Cdd:pfam12128  246 LQQEFNTLESAELRLSHLHFGYKSDETLIASRQEERQETSAELNQLLRTLDDQWKEKRDELNGELSAADAAVAKDRSELE 325

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  380 ILQEKISQLED-----RAAQLQGSPA--------PEKGEVLGDALQLDTLKQEAAKLATD---NTELQARVETLECERGK 443
Cdd:pfam12128  326 ALEDQHGAFLDadietAAADQEQLPSwqselenlEERLKALTGKHQDVTAKYNRRRSKIKeqnNRDIAGIKDKLAKIREA 405

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  444 QEAQLLAERGHFE------------------EEKRQLASLVADLQSSVsNLSQAKEELQQASQAQGAQLTAQLASLTALN 505
Cdd:pfam12128  406 RDRQLAVAEDDLQaleselreqleagklefnEEEYRLKSRLGELKLRL-NQATATPELLLQLENFDERIERAREEQEAAN 484

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  506 A---TLQQQDQELTSLKEQAKKEQAQMLQTLQEQEQAAQGLRQQ--------VEQLSSSLKLKEQQLEEAAKEQEAARQD 574
Cdd:pfam12128  485 AeveRLQSELRQARKRRDQASEALRQASRRLEERQSALDELELQlfpqagtlLHFLRKEAPDWEQSIGKVISPELLHRTD 564

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  575 HAQQLATIVEAREASVRERDAARQQLETleKEKDAKLESLQQQLQASNEARDTAQTSVTQAQREKAELSQKIGELHACIE 654
Cdd:pfam12128  565 LDPEVWDGSVGGELNLYGVKLDLKRIDV--PEWAASEEELRERLDKAEEALQSAREKQAAAEEQLVQANGELEKASREET 642

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  655 AAHQEQRQAQAHVTELEAQLKAEQ---QKATEREK--VVQEKVQLQEQLQALEETLKivrgsleeekcraaDALKEQQRH 729
Cdd:pfam12128  643 FARTALKNARLDLRRLFDEKQSEKdkkNKALAERKdsANERLNSLEAQLKQLDKKHQ--------------AWLEEQKEQ 708

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  730 ATEmeaetrHLMEQREQEQKELEQEKAERKGLEARLQQLEEAHQAETEALRHELAGATAAQHGAE---SEREQLLREVES 806
Cdd:pfam12128  709 KRE------ARTEKQAYWQVVEGALDAQLALLKAAIAARRSGAKAELKALETWYKRDLASLGVDPdviAKLKREIRTLER 782

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  807 WQKRVEARQQEEARYGAMFQEQLMALKGEHGKIGQEEQKEAGEIhgEGQTGQQQSQLAQLHACLAKALQQVQEKEARAQK 886
Cdd:pfam12128  783 KIERIAVRRQEVLRYFDWYQETWLQRRPRLATQLSNIERAISEL--QQQLARLIADTKLRRAKLEMERKASEKQQVRLSE 860

                          650       660       670
                   ....*....|....*....|....*....|....*..
gi 1958645968  887 LLDDLSALREKMA-----ATNKEVACLKALVLKAGEQ 918
Cdd:pfam12128  861 NLRGLRCEMSKLAtlkedANSEQAQGSIGERLAQLED 897
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 354-703 3.29e-08

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 59.20  E-value: 3.29e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  354 AEKQAHLESelstALQDKKCLEEKSEILQEKISQLEDRAAQLQGSPAPEKGevLGDALQLD----TLKQEAAKLATDNTE 429
Cdd:COG3096    278 NERRELSER----ALELRRELFGARRQLAEEQYRLVEMARELEELSARESD--LEQDYQAAsdhlNLVQTALRQQEKIER 351

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  430 LQARVETLE----------CERGKQEAQLLAERGHFEEEKRQLASLVADLQSSVSNLS----------QAKEELQQASQA 489
Cdd:COG3096    352 YQEDLEELTerleeqeevvEEAAEQLAEAEARLEAAEEEVDSLKSQLADYQQALDVQQtraiqyqqavQALEKARALCGL 431

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  490 QGAQLTAQLASLTALNATLQQQDQELTSLKEQ------AKKEQAQMLQTLQ------EQEQAAQGLRQQVEQLSSsLKLK 557
Cdd:COG3096    432 PDLTPENAEDYLAAFRAKEQQATEEVLELEQKlsvadaARRQFEKAYELVCkiagevERSQAWQTARELLRRYRS-QQAL 510

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  558 EQQLEEAAKEQEAARQDHAQQLATIVEAREASVR--ERDAARQQLETLEKEKDAKLESLQQQLQASNEARDTAQTSVTQA 635
Cdd:COG3096    511 AQRLQQLRAQLAELEQRLRQQQNAERLLEEFCQRigQQLDAAEELEELLAELEAQLEELEEQAAEAVEQRSELRQQLEQL 590

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1958645968  636 QREKAELSQKIGELHACIEAAHQEQRQAQAHVTELEAQLKAEQQKATEREKVVQEKVQLQEQLQALEE 703
Cdd:COG3096    591 RARIKELAARAPAWLAAQDALERLREQSGEALADSQEVTAAMQQLLEREREATVERDELAARKQALES 658
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1114-1578 4.65e-08

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 58.54  E-value: 4.65e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1114 PEVEALRAEISKLERQWQQQQQQVEGLThSLESERACRAEQDKALETLQGQLEEKARELGHNQAASASAQRELQALRAKA 1193
Cdd:PRK03918   214 SELPELREELEKLEKEVKELEELKEEIE-ELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKEKA 292

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1194 QDHSKAEE---EWKAQVARGQQEAERKSSLISSLEEEVSILNRQVLEKEGESKELKRLV--VAESEKSQKLEERLRLLQV 1268
Cdd:PRK03918   293 EEYIKLSEfyeEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEkrLEELEERHELYEEAKAKKE 372

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1269 ETASSSARAA----ERSSALREEVQSLREEVEKQRVVSENLRQELASQAERAEESGQELKAWQ----------------- 1327
Cdd:PRK03918   373 ELERLKKRLTgltpEKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKgkcpvcgrelteehrke 452

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1328 ----------------EKFFQKEQALSALQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKRFREEIEQS-------KQ 1384
Cdd:PRK03918   453 lleeytaelkriekelKEIEEKERKLRKELRELEKVLKKESELIKLKELAEQLKELEEKLKKYNLEELEKKaeeyeklKE 532

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1385 AAGGLQAELMRAQRELGELGSLRQKIVEQERAAQQLRAEKASYAEQLSmlKKAHGLLAEENRGLGERANLGRQFLEVeld 1464
Cdd:PRK03918   533 KLIKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELE--ELGFESVEELEERLKELEPFYNEYLEL--- 607

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1465 QAREKYVQELAAVRTDAETHLAEMRQEAQSTSRELEVMTAKYESAKVKVLEERQRFQEER--------QKLTAQVEELNK 1536
Cdd:PRK03918   608 KDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEEEYEELREEylelsrelAGLRAELEELEK 687

                          490       500       510       520
                   ....*....|....*....|....*....|....*....|..
gi 1958645968 1537 KLTESEQASRvqqqKLKAFQAQGGESQQEVQCLQTQLSELQA 1578
Cdd:PRK03918   688 RREEIKKTLE----KLKEELEEREKAKKELEKLEKALERVEE 725
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 931-1679 6.67e-08

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 58.04  E-value: 6.67e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  931 RAGNQESDWEEEQaRPLGSTQAALKAVQREAEQMGGELERLRA---------ALMQSQGQQQEVRGQQEREVARLTQERG 1001
Cdd:COG3096    286 RALELRRELFGAR-RQLAEEQYRLVEMARELEELSARESDLEQdyqaasdhlNLVQTALRQQEKIERYQEDLEELTERLE 364

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1002 QAQADLAQEKAAKAELEMRLQNT---LNEQRVEFAALQEALTHAMT------------------------EKEGKDQELA 1054
Cdd:COG3096    365 EQEEVVEEAAEQLAEAEARLEAAeeeVDSLKSQLADYQQALDVQQTraiqyqqavqalekaralcglpdlTPENAEDYLA 444

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1055 KLREQEAAQISELKALQQTLEELKKKEKEHPTGGARGEDASGDGPGSQLHTPGKT--------EAPGPEVEALRAEISKL 1126
Cdd:COG3096    445 AFRAKEQQATEEVLELEQKLSVADAARRQFEKAYELVCKIAGEVERSQAWQTAREllrryrsqQALAQRLQQLRAQLAEL 524

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1127 ERQWQQQQQQV---EGLTHSLESERACRAEQDKALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQDHSKAEEEW 1203
Cdd:COG3096    525 EQRLRQQQNAErllEEFCQRIGQQLDAAEELEELLAELEAQLEELEEQAAEAVEQRSELRQQLEQLRARIKELAARAPAW 604

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1204 -KAQVARGQQEAERKSSLISSleEEVSILNRQVLEKEGESKELKRLVVAESEKSQKLEERL---------RLLQV----- 1268
Cdd:COG3096    605 lAAQDALERLREQSGEALADS--QEVTAAMQQLLEREREATVERDELAARKQALESQIERLsqpggaedpRLLALaerlg 682

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1269 --------------ETASSSARAAERSSAL--------REEVQSL-----------------------REEVEKQRVVSE 1303
Cdd:COG3096    683 gvllseiyddvtleDAPYFSALYGPARHAIvvpdlsavKEQLAGLedcpedlyliegdpdsfddsvfdAEELEDAVVVKL 762

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1304 NLRQ-------EL-----ASQAERAEESGQELKAWQEKFFQKEQALSALQLEHTSTQALVsellpAKHLCQQlqaeqaaa 1371
Cdd:COG3096    763 SDRQwrysrfpEVplfgrAAREKRLEELRAERDELAEQYAKASFDVQKLQRLHQAFSQFV-----GGHLAVA-------- 829

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1372 ekrFREEIEQSKQAaggLQAELMRAQRELgelgslrqkiVEQERAAQQLRAEKASYAEQLSMLKKAHG---LLAEEnrGL 1448
Cdd:COG3096    830 ---FAPDPEAELAA---LRQRRSELEREL----------AQHRAQEQQLRQQLDQLKEQLQLLNKLLPqanLLADE--TL 891

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1449 GERanlgRQFLEVELDQARE--KYVQELAAVRTDAETHLAEMRQEAQStsreLEVMTAKYESAKvkvleerqrfqEERQK 1526
Cdd:COG3096    892 ADR----LEELREELDAAQEaqAFIQQHGKALAQLEPLVAVLQSDPEQ----FEQLQADYLQAK-----------EQQRR 952

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1527 LTAQVEELnkklteSEQASRVQQQKLKAFQAQGGESQQEVQCLQTQLSELQAQLSQKEQAAEHYKLQMEKA-------KT 1599
Cdd:COG3096    953 LKQQIFAL------SEVVQRRPHFSYEDAVGLLGENSDLNEKLRARLEQAEEARREAREQLRQAQAQYSQYnqvlaslKS 1026

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1600 HYDAKKQQNQELREQLQDLEQLQKDNKELRSETERlgRELQQAGLKTKeaeQACRHLTAQVRSLEAQVAHADQQLRDLGK 1679
Cdd:COG3096   1027 SRDAKQQTLQELEQELEELGVQADAEAEERARIRR--DELHEELSQNR---SRRSQLEKQLTRCEAEMDSLQKRLRKAER 1101
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
412-617 7.30e-08

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 58.00  E-value: 7.30e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  412 QLDTLKQEAAKLATDNTELQARVETLECERGKQEAQLLaerghfEEEKRQLASLVADLQSSVSNLSQAKEELQqasqaqg 491
Cdd:COG4913    256 PIRELAERYAAARERLAELEYLRAALRLWFAQRRLELL------EAELEELRAELARLEAELERLEARLDALR------- 322

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  492 aqltaqlASLTALNATLQQQDQELtslKEQAKKEQAQMLQTLQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEAA 571
Cdd:COG4913    323 -------EELDELEAQIRGNGGDR---LEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAAL 392

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*.
gi 1958645968  572 RQDHAQQLATIVEAREASVRERDAARQQLETLEKEkdakLESLQQQ 617
Cdd:COG4913    393 LEALEEELEALEEALAEAEAALRDLRRELRELEAE----IASLERR 434
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 463-681 1.07e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 56.31  E-value: 1.07e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  463 ASLVADLQSSVSNLSQAKEELQQASQAQGAQLTAQLASLTALNATLQQQDQELTSLKEQAKKEQAQMLQTLQEQEQAAQG 542
Cdd:COG4942     19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE 98

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  543 LRQQVEQLSSSLKlKEQQLEEAAKEQEAARQDHAQQ-------LATIVEAREASVRERDAARQQLETLEKEKDAKLESLQ 615
Cdd:COG4942     99 LEAQKEELAELLR-ALYRLGRQPPLALLLSPEDFLDavrrlqyLKYLAPARREQAEELRADLAELAALRAELEAERAELE 177

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1958645968  616 QQLQASNEARDTAQTSVTQAQREKAELSQKIGELHACIEAAHQEQRQAQAHVTELEAQLKAEQQKA 681
Cdd:COG4942    178 ALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERT 243
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
458-1007 1.07e-07

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 57.23  E-value: 1.07e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  458 EKRQLASLVADLQSSVSNLSQAKEELQQASQAQgaqltAQLASLTALNATLQQQDQELTSLKEQAKKEQAQMLQT-LQEQ 536
Cdd:COG4913    219 EEPDTFEAADALVEHFDDLERAHEALEDAREQI-----ELLEPIRELAERYAAARERLAELEYLRAALRLWFAQRrLELL 293

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  537 EQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEAARQDHAQQLATIVEAREASVRERDAARQQLETLEKEKDAKLESLQQ 616
Cdd:COG4913    294 EAELEELRAELARLEAELERLEARLDALREELDELEAQIRGNGGDRLEQLEREIERLERELEERERRRARLEALLAALGL 373

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  617 QLQASneaRDTAQTSVTQAQREKAELSQKIGELHACIEAAHQEQRQAQAHVTELEAQLKA-EQQKATEREKVVQEKVQLQ 695
Cdd:COG4913    374 PLPAS---AEEFAALRAEAAALLEALEEELEALEEALAEAEAALRDLRRELRELEAEIASlERRKSNIPARLLALRDALA 450

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  696 EQLQALEETLKIV-------------RGSLE------------EEKCRAA-----DALKEQQRHATEmEAETRHLMEQRE 745
Cdd:COG4913    451 EALGLDEAELPFVgelievrpeeerwRGAIErvlggfaltllvPPEHYAAalrwvNRLHLRGRLVYE-RVRTGLPDPERP 529

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  746 QEQKELEQEKAERKG------LEARLQQLEEAHQAET-EALRHELAGATAAQHGAESEReqllreveSWQKRVEARQQEE 818
Cdd:COG4913    530 RLDPDSLAGKLDFKPhpfrawLEAELGRRFDYVCVDSpEELRRHPRAITRAGQVKGNGT--------RHEKDDRRRIRSR 601

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  819 ARYGAMFQEQLMALKGEHGKIGQEEQKEAGEIHG-EGQTGQQQSQLAQLHAC---------LAKALQQVQEKEARAQKLL 888
Cdd:COG4913    602 YVLGFDNRAKLAALEAELAELEEELAEAEERLEAlEAELDALQERREALQRLaeyswdeidVASAEREIAELEAELERLD 681

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  889 ---DDLSALREKMAATNKEVACLKALVLKAGEQQAAASHELKeppragnqesDWEEEQARplgSTQAALKAVQREAEQMG 965
Cdd:COG4913    682 assDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELE----------QAEEELDE---LQDRLEAAEDLARLELR 748

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|..
gi 1958645968  966 GELERLRAALMQSQgQQQEVRGQQEREVARLTQERGQAQADL 1007
Cdd:COG4913    749 ALLEERFAAALGDA-VERELRENLEERIDALRARLNRAEEEL 789
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 1152-1650 1.20e-07

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 57.04  E-value: 1.20e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1152 AEQDKALETLQGQLEEKARELGHNQAASASAQREL--QALRAKAQDHSKAEEEWKaQVARGQQEAERKsslISSLEEEVS 1229
Cdd:pfam05483  168 AEKTKKYEYEREETRQVYMDLNNNIEKMILAFEELrvQAENARLEMHFKLKEDHE-KIQHLEEEYKKE---INDKEKQVS 243

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1230 ILNRQVLEKEGESKELKRLVVAESEKSQKLEERLRLLQVETASSSARAAERSSALREEVQSLREEVEKQRVVSENLRQEL 1309
Cdd:pfam05483  244 LLLIQITEKENKMKDLTFLLEESRDKANQLEEKTKLQDENLKELIEKKDHLTKELEDIKMSLQRSMSTQKALEEDLQIAT 323

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1310 ASQAERAEESgqelKAWQEKFFQKEQALSALQLEHTSTQALVSELLPAKhlcqqlqaeqaaaekrfREEIEQSKQAAGGL 1389
Cdd:pfam05483  324 KTICQLTEEK----EAQMEELNKAKAAHSFVVTEFEATTCSLEELLRTE-----------------QQRLEKNEDQLKII 382

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1390 QAELMRAQRELGELGSLRQKIVEQERAAQQLRAEKasyaEQLSMLKKAHGLLAEENRGLGERAnlgrqfleVELDQAREK 1469
Cdd:pfam05483  383 TMELQKKSSELEEMTKFKNNKEVELEELKKILAED----EKLLDEKKQFEKIAEELKGKEQEL--------IFLLQAREK 450

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1470 YVQELaavrtdaETHLAEMRQEAQSTSRELEVMTAKYESAKVKVLE----------ERQRFQEERQKLTAQVEELNKKLT 1539
Cdd:pfam05483  451 EIHDL-------EIQLTAIKTSEEHYLKEVEDLKTELEKEKLKNIEltahcdklllENKELTQEASDMTLELKKHQEDII 523

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1540 ESEQASRVQQQKLKAFQAQGGESQQEVQCLQTQL----SELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQELREQL 1615
Cdd:pfam05483  524 NCKKQEERMLKQIENLEEKEMNLRDELESVREEFiqkgDEVKCKLDKSEENARSIEYEVLKKEKQMKILENKCNNLKKQI 603

                          490       500       510
                   ....*....|....*....|....*....|....*....
gi 1958645968 1616 QD----LEQLQKDNKELRSETERLGRELQQAGLKTKEAE 1650
Cdd:pfam05483  604 ENknknIEELHQENKALKKKGSAENKQLNAYEIKVNKLE 642
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
343-820 1.23e-07

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 57.23  E-value: 1.23e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  343 IEEHSKASQEWAEKQAHLESELSTAlqDKKCLEEKSEILQEKISQLEDRAAQLQGspapekgevlgdalQLDTLKQEAAK 422
Cdd:COG4913    257 IRELAERYAAARERLAELEYLRAAL--RLWFAQRRLELLEAELEELRAELARLEA--------------ELERLEARLDA 320

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  423 LATDNTELQARVETLEcerGKQEAQLLAERGHFEEEKRQLASLVADLQSSVSNLSQAKEELQQASQAQGAQLTAQLASLT 502
Cdd:COG4913    321 LREELDELEAQIRGNG---GDRLEQLEREIERLERELEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALE 397

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  503 ALNATLQQQDQELTSLKEQAKKEQAQMLQTLQEQEQAA----QGLRQQVEQLSSSLKLKEQQLE------EAAKEQEAAR 572
Cdd:COG4913    398 EELEALEEALAEAEAALRDLRRELRELEAEIASLERRKsnipARLLALRDALAEALGLDEAELPfvgeliEVRPEEERWR 477

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  573 -----------------QDHAQQLATIVEAREAS-------VRERDAARQQLETLEKEKDAKLES--------LQQQLQ- 619
Cdd:COG4913    478 gaiervlggfaltllvpPEHYAAALRWVNRLHLRgrlvyerVRTGLPDPERPRLDPDSLAGKLDFkphpfrawLEAELGr 557

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  620 -------ASNEARDTAQTSVTQ----------------------------AQREKAELSQKIGELHACIEAAHQEQRQAQ 664
Cdd:COG4913    558 rfdyvcvDSPEELRRHPRAITRagqvkgngtrhekddrrrirsryvlgfdNRAKLAALEAELAELEEELAEAEERLEALE 637

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  665 AHVTELEAQLKAEQQKATEREKVVqEKVQLQEQLQALEETLKIVRgsleeekcRAADALKEQQRHATEMEAETRHLMEQR 744
Cdd:COG4913    638 AELDALQERREALQRLAEYSWDEI-DVASAEREIAELEAELERLD--------ASSDDLAALEEQLEELEAELEELEEEL 708

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1958645968  745 EQEQKELEQEKAERKGLEARLQQLEEAHQAETEALRHELAGATAAQHGAESEREQLLREVESWQKRVEARQQEEAR 820
Cdd:COG4913    709 DELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGDAVERELRENLEERIDALRARLNR 784
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1241-1677 1.63e-07

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 56.70  E-value: 1.63e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1241 ESKELKRLVVAESEKSQKLEERLRLLQvETASSSARAAERSSALREEVQSLREEVEKQRVVSE--NLRQELASQAERAEE 1318
Cdd:COG4717     72 ELKELEEELKEAEEKEEEYAELQEELE-ELEEELEELEAELEELREELEKLEKLLQLLPLYQEleALEAELAELPERLEE 150

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1319 SGQELKAWQEKFFQKEQALSALQLEHTSTQALVSELLPAKHlcqQLQAEQAAAEKRFREEIEQSKQAAGGLQAELMRAQR 1398
Cdd:COG4717    151 LEERLEELRELEEELEELEAELAELQEELEELLEQLSLATE---EELQDLAEELEELQQRLAELEEELEEAQEELEELEE 227

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1399 ELGELGSLRQKIVEQERAaQQLRAEKASYAEQLSMLKKAHGLLAEENRGLGERANLGRQFLEVELDQAREKYVQELAAVR 1478
Cdd:COG4717    228 ELEQLENELEAAALEERL-KEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASLGKEAEE 306

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1479 TDAETHLAEMRQEA-QSTSRELEVMTAKYESAKVKVLEERQRFQEERQKLTAQVEELNKKLTESEQAS---RVQQQKLKA 1554
Cdd:COG4717    307 LQALPALEELEEEElEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQEIAAllaEAGVEDEEE 386

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1555 FQAQGGESQQEVQcLQTQLSELQAQLSQKEQAAEHYkLQMEKAKTHYDAKKQQNQELREQLQDLEQLQKDNKELRSETER 1634
Cdd:COG4717    387 LRAALEQAEEYQE-LKEELEELEEQLEELLGELEEL-LEALDEEELEEELEELEEELEELEEELEELREELAELEAELEQ 464

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|....*
gi 1958645968 1635 L--GRELQQAGLKTKEAEQACRHLTAQVRSLEAQVAHADQQLRDL 1677
Cdd:COG4717    465 LeeDGELAELLQELEELKAELRELAEEWAALKLALELLEEAREEY 509
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 512-1337 1.67e-07

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 56.90  E-value: 1.67e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  512 DQELTSLKEQAKKEQAQmLQTLQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEAARQDHAQQlATIVEAREASVR 591
Cdd:pfam02463  159 EEEAAGSRLKRKKKEAL-KKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEE-YLLYLDYLKLNE 236

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  592 ERDAARQQLETLEKEKDAKLESLQQQLQASNEARDTAQTSVTQAQREKAELSQKIGELhacIEAAHQEQRQAQAHVTELE 671
Cdd:pfam02463  237 ERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKE---EEELKSELLKLERRKVDDE 313

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  672 AQLKAEQQKATEREKVVQEKVQLQEQLQALEETLKIVRGSLEEEKCRAADALKEQQRHATEMEAETRHLMEQREQEQKEL 751
Cdd:pfam02463  314 EKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLK 393

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  752 EQEKA----------------ERKGLEARLQQLEEAHQAETEALRHELAGATAAQHGAE------------SEREQLLRE 803
Cdd:pfam02463  394 EEELElkseeekeaqlllelaRQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEElekqelkllkdeLELKKSEDL 473

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  804 VESWQKRVEARQQEEARYGAMFQEQLMALKGEHGKIGQEEQKEAGEIHGEGQTGQQQSQLAQLHACLAKALQQVQEKEAR 883
Cdd:pfam02463  474 LKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEV 553

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  884 AQKLLDDLSALREKMAATNKEVACLKALVLKAGEQQAAASHELKEPPRAGNQESDWEEEQARPLGSTQAALKAVQREAEQ 963
Cdd:pfam02463  554 SATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTE 633

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  964 MGGELERLRAALMQSQGQQQEVRGQQER-EVARLTQERGQAQADLAQEKAAKAELEMRLQNTLNEQRVEFAALQEALTHA 1042
Cdd:pfam02463  634 LTKLKESAKAKESGLRKGVSLEEGLAEKsEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELK 713

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1043 MTEKEGKDQELAKLREQEAAQISELKALQQTLEELKKKEKEHPTGGARGEdasgdgpgsQLHTPGKTEAPGPEVEALRAE 1122
Cdd:pfam02463  714 KLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKE---------EEKSELSLKEKELAEEREKTE 784

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1123 ISKLERQWQQQQQQVEGLTHSLESERACRAEQDKALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQDHSKAEEE 1202
Cdd:pfam02463  785 KLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEIT 864

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1203 WKAQVARG------QQEAERKSSLISSLEEEVSILNRQVLEKEGESKELKRLVVAESEKSQKLEERLRLLQVETASSSAR 1276
Cdd:pfam02463  865 KEELLQELllkeeeLEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEE 944

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1958645968 1277 AAERSSA------LREEVQSLREEVEKQRVVSENLRQELASQAERAEESGQELKAWQEKFFQKEQAL 1337
Cdd:pfam02463  945 ADEKEKEennkeeEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAI 1011
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 498-735 2.19e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 55.54  E-value: 2.19e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  498 LASLTALNATLQQQDQeltslKEQAKKEQAQMLQTLQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEAARQDHAQ 577
Cdd:COG4942      6 LLALLLALAAAAQADA-----AAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAA 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  578 QLATIVEAReasvRERDAARQQLETLEKEKDAKLESLQQQLQASNEARDTAQTSVTQAQREKAELSQKIGELHACIEAAH 657
Cdd:COG4942     81 LEAELAELE----KEIAELRAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELR 156

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1958645968  658 QEQRQAQAHVTELEAQLKAEQQKATEREkvvQEKVQLQEQLQALEETLKIVRGSLEEEKCRAADALKEQQRHATEMEA 735
Cdd:COG4942    157 ADLAELAALRAELEAERAELEALLAELE---EERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIAR 231
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
586-1005 2.35e-07

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 55.93  E-value: 2.35e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  586 REASVRERDAARQQLETLEkEKDAKLESLQQQLQASNEARDTAQTSVTQAQREKAELSQKIGelhacIEAAHQEQRQAQA 665
Cdd:COG4717     66 PELNLKELKELEEELKEAE-EKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQ-----LLPLYQELEALEA 139

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  666 HVTELEAQLKAEQQKATEREKVVQEKVQLQEQLQALEETLKIVRGSLEEEKcraADALKEQQRHATEMEAETRHLMEQRE 745
Cdd:COG4717    140 ELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLAT---EEELQDLAEELEELQQRLAELEEELE 216

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  746 QEQKELEQEKAERKGLEARLQQLEEAHQAETEALRHELAGATAAQHGAESEREQLLREV-----------------ESWQ 808
Cdd:COG4717    217 EAQEELEELEEELEQLENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIagvlflvlgllallfllLARE 296

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  809 KRVEARQQEEARYGAMF----QEQLMALKGEHGKIGQEEQKEAGE-IHGEGQTGQQQSQLAQLHACLAKALQQVQEKEAR 883
Cdd:COG4717    297 KASLGKEAEELQALPALeeleEEELEELLAALGLPPDLSPEELLElLDRIEELQELLREAEELEEELQLEELEQEIAALL 376

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  884 AQKLLDDLSALREKMAATNKEVAcLKALVLKAGEQQAAASHELKEPPRAGNQEsDWEEEqarpLGSTQAALKAVQREAEQ 963
Cdd:COG4717    377 AEAGVEDEEELRAALEQAEEYQE-LKEELEELEEQLEELLGELEELLEALDEE-ELEEE----LEELEEELEELEEELEE 450

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|....
gi 1958645968  964 MGGELERLRAAL--MQSQGQQQEVRGQQEREVARLTQERGQAQA 1005
Cdd:COG4717    451 LREELAELEAELeqLEEDGELAELLQELEELKAELRELAEEWAA 494
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1385-1627 3.80e-07

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 54.77  E-value: 3.80e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1385 AAGGLQAELMRAQRELGELGSLRQKIVEQERAAQQLRAEKASYAEQLSMLKKAHGLLAEENRGLGERANLGRQFLEvELD 1464
Cdd:COG4942     11 LALAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELA-ELE 89

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1465 QAREKYVQELAAVRTDAETHLAEMrQEAQSTSRELEVMTAKYESAKVKVLEERQRFQEERQKLTAQVEELNKKLTESEQA 1544
Cdd:COG4942     90 KEIAELRAELEAQKEELAELLRAL-YRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAE 168

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1545 SRVQQQKLKAFQAQggesqqevqcLQTQLSELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQELREQLQDLEQLQKD 1624
Cdd:COG4942    169 LEAERAELEALLAE----------LEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAA 238


                   ...
gi 1958645968 1625 NKE 1627
Cdd:COG4942    239 AAE 241
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1199-1643 3.97e-07

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 55.46  E-value: 3.97e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1199 AEEEWKAQVARGQ-QEAERKSSLISSLEEEVsilnRQVLEKEGESKElkrlvvaESEKSQKLEERLRLLQVETASSSARA 1277
Cdd:TIGR02169  166 AEFDRKKEKALEElEEVEENIERLDLIIDEK----RQQLERLRRERE-------KAERYQALLKEKREYEGYELLKEKEA 234

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1278 AERS-SALREEVQSLREEVEKQRVVSENLRQELASQAERAEESGQELKAWQEkffqkeqalsalqlehtstqalvsellp 1356
Cdd:TIGR02169  235 LERQkEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGE---------------------------- 286

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1357 akhlcqqlqaeqaaaekrfrEEIEQSKQAAGGLQAELMRAQRelgelgSLRQKIVEQERAAQQLRAEKASYAEQLSMLKK 1436
Cdd:TIGR02169  287 --------------------EEQLRVKEKIGELEAEIASLER------SIAEKERELEDAEERLAKLEAEIDKLLAEIEE 340

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1437 AHGLLAEENRglgERANLGRQFleVELDQAREKYVQELAAVRTDAethlAEMRQEAQSTSRELEVMTAKYESAKvkvlEE 1516
Cdd:TIGR02169  341 LEREIEEERK---RRDKLTEEY--AELKEELEDLRAELEEVDKEF----AETRDELKDYREKLEKLKREINELK----RE 407

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1517 RQRFQEERQKLTAQVEELNKKLTESEQasrvqqqklkafqaqggesqqEVQCLQTQLSELQAQLSQKEQAAEHYKLQMEK 1596
Cdd:TIGR02169  408 LDRLQEELQRLSEELADLNAAIAGIEA---------------------KINELEEEKEDKALEIKKQEWKLEQLAADLSK 466

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|....*..
gi 1958645968 1597 AKthydakkqqnQELREQLQDLEQLQKDNKELRSETERLGRELQQAG 1643
Cdd:TIGR02169  467 YE----------QELYDLKEEYDRVEKELSKLQRELAEAEAQARASE 503
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 1209-1588 4.83e-07

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 55.34  E-value: 4.83e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1209 RGQQEAERKSSLISSLEEEVSILNRQVLEKEGE----SKELKRLVVAESEKSQKLE---ERLRLLQvetasSSARAAERS 1281
Cdd:COG3096    275 RHANERRELSERALELRRELFGARRQLAEEQYRlvemARELEELSARESDLEQDYQaasDHLNLVQ-----TALRQQEKI 349

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1282 SALREEVQSLREEVEKQRVVSENL---RQELASQAERAEESGQELKAwQEKFFQkeQALSALQLEHTSTQALVSELLPAK 1358
Cdd:COG3096    350 ERYQEDLEELTERLEEQEEVVEEAaeqLAEAEARLEAAEEEVDSLKS-QLADYQ--QALDVQQTRAIQYQQAVQALEKAR 426

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1359 HLCQQLQAEQAAAEKR---FREEIEQSKQAAGGLQAELMRAQ---RELGELGSLRQKI---VEQERAAQQLRAEKASYAE 1429
Cdd:COG3096    427 ALCGLPDLTPENAEDYlaaFRAKEQQATEEVLELEQKLSVADaarRQFEKAYELVCKIageVERSQAWQTARELLRRYRS 506

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1430 QLSMLKKAHGL---LAEENRGLGERANLGRQFleveldqarEKYVQELAAVRTDAEThLAEMRQEAQSTSRELEVMTAky 1506
Cdd:COG3096    507 QQALAQRLQQLraqLAELEQRLRQQQNAERLL---------EEFCQRIGQQLDAAEE-LEELLAELEAQLEELEEQAA-- 574

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1507 esakvKVLEERQRFQEERQKLTAQVEELNKKltesEQASRVQQQKLKAFQAQGGE----SQQEVQCLQTQLSELQAQLSQ 1582
Cdd:COG3096    575 -----EAVEQRSELRQQLEQLRARIKELAAR----APAWLAAQDALERLREQSGEaladSQEVTAAMQQLLEREREATVE 645


                   ....*.
gi 1958645968 1583 KEQAAE 1588
Cdd:COG3096    646 RDELAA 651
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1504-1711 6.11e-07

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 55.06  E-value: 6.11e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1504 AKYESAKVKVLEERQRFQEERQKLTAQVEELNKKLTESEQASRVQQQKLKAFQAQGGESQQEVQCLQTQLSELQAQLSQK 1583
Cdd:TIGR02168  242 EELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEEL 321

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1584 EQAAEHYKLQMEKAKTHYDAKKQQNQELREQLQDLEQLQKDNKELRSETERLGRELQQAGL----KTKEAEQACRHLTAQ 1659
Cdd:TIGR02168  322 EAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLEtlrsKVAQLELQIASLNNE 401

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1958645968 1660 VRSLEAQVAHADQQLRDLGkfQVATDALKSREPQVKPQLDLSIDSLDLSLEE 1711
Cdd:TIGR02168  402 IERLEARLERLEDRRERLQ--QEIEELLKKLEEAELKELQAELEELEEELEE 451
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1221-1711 6.37e-07

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 54.64  E-value: 6.37e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1221 ISSLEEEVSILNRQVLEKEGESKELKRLVVAESEKSQKLEERLRLLQVETASSSARAaerssalreevqslrEEVEKQRV 1300
Cdd:TIGR04523  105 LSKINSEIKNDKEQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKY---------------NDLKKQKE 169

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1301 VSENLRQELASQAERAEesgQELKAWQEKFFQKEQALSALQLEHTSTQALVSELLPAKhlcqqlqaeqaAAEKRFREEIE 1380
Cdd:TIGR04523  170 ELENELNLLEKEKLNIQ---KNIDKIKNKLLKLELLLSNLKKKIQKNKSLESQISELK-----------KQNNQLKDNIE 235

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1381 QSKQAAGGLQAELMRAQRELGELGSLRQKIVEQERAAQ-----------QLRAEKASYAEQLSMLK--KAHGLLAEENRG 1447
Cdd:TIGR04523  236 KKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQkeleqnnkkikELEKQLNQLKSEISDLNnqKEQDWNKELKSE 315

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1448 LGERANLGRQfLEVELDQArEKYVQELAAVRTDAETHLAEMRQEAQSTSRELEVMTAKYEsakvKVLEERQRFQEERQKL 1527
Cdd:TIGR04523  316 LKNQEKKLEE-IQNQISQN-NKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIE----KLKKENQSYKQEIKNL 389

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1528 TAQVEELNKKLTESEQASRVQQQKLKAFQAQGGESQQEVQCLQTQLSELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQ 1607
Cdd:TIGR04523  390 ESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRESLETQ 469

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1608 ----NQELREQLQDLEQLQKDNKELRSETERLGRELQQAGLKTKEAEQACRHLTAQVRSLEAQVAHADQQLRDLGKfqva 1683
Cdd:TIGR04523  470 lkvlSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLED---- 545

                          490       500
                   ....*....|....*....|....*...
gi 1958645968 1684 tDALKSREPQVKPQLDLSIDSLDLSLEE 1711
Cdd:TIGR04523  546 -ELNKDDFELKKENLEKEIDEKNKEIEE 572
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 310-1028 6.37e-07

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 54.97  E-value: 6.37e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  310 KISQLSEENGDLSFKVREFANHLQQLQGAFNDLIEEHSKASQEWAEKQAHLESELSTALQDKKCLEEKSEILQEKISQLE 389
Cdd:TIGR00618  177 QYTQLALMEFAKKKSLHGKAELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREALQQTQQSHAYLTQKREAQEEQL 256

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  390 DRAAQLQGSPApekgevlgdalQLDTLKQEAAKLATDNTELqarvetlecERGKQEAQLLAERGHFEEEKRQLASLVADL 469
Cdd:TIGR00618  257 KKQQLLKQLRA-----------RIEELRAQEAVLEETQERI---------NRARKAAPLAAHIKAVTQIEQQAQRIHTEL 316

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  470 QSSVSNLSQAKEELQQASQAQGAQLTAQLASLTALNAT--LQQQDQELTSLKEQAKKEQA--QMLQTLQEQEQAAqglrQ 545
Cdd:TIGR00618  317 QSKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQEihIRDAHEVATSIREISCQQHTltQHIHTLQQQKTTL----T 392

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  546 QVEQLSSSLKLKEQQLEEAAKEQEAARQDHAQQLATIVEAREASVRERDAARQQLETLEKEKDAKLESLQQQLQASNEAr 625
Cdd:TIGR00618  393 QKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQSLKER- 471

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  626 dtaqtsvTQAQREKAELSQKIGELHACIEAAHQEQRQAQAHVTELEAQLKAEQQKATEREKVVQEKVQLQEQLQALEETL 705
Cdd:TIGR00618  472 -------EQQLQTKEQIHLQETRKKAVVLARLLELQEEPCPLCGSCIHPNPARQDIDNPGPLTRRMQRGEQTYAQLETSE 544

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  706 KIVRGSLEEEKCRAADALKEQQRHATEMEAETRHLMEQREQEQKELEQEKAERKGLEARLQ---QLEEAHQAETEALRHE 782
Cdd:TIGR00618  545 EDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEaedMLACEQHALLRKLQPE 624

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  783 LAGATAAQHGAESEREQLLREVESWQKRVEARQQEEARYGAMFQEQLMALKGEHGKIGQEEQKEAGEIHGEGQT-GQQQS 861
Cdd:TIGR00618  625 QDLQDVRLHLQQCSQELALKLTALHALQLTLTQERVREHALSIRVLPKELLASRQLALQKMQSEKEQLTYWKEMlAQCQT 704

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  862 QLAQLHACLAKALQQVQEKEARAQKLLDDLSALREKMAATNKEVACLKALVLKAgeqQAAASHELKEPPRAGNQESDWEE 941
Cdd:TIGR00618  705 LLRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQARTVLKA---RTEAHFNNNEEVTAALQTGAELS 781

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  942 EQARPLGSTQAALKAVQREAEQMGGELERLRAALMQSQGQQQEVRGQQEREVARLTQERGQAQADLAQEKAAKAELEMRL 1021
Cdd:TIGR00618  782 HLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQCETLVQEEEQFLSRLEEKSATLGEITHQLLKYEECSKQL 861


                   ....*..
gi 1958645968 1022 QNTLNEQ 1028
Cdd:TIGR00618  862 AQLTQEQ 868
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 214-483 1.08e-06

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 54.30  E-value: 1.08e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  214 MRRLKKQLADERNNRDELELELSESLKLLTEKDAQIAMMQQRidhlalLNEKQAASPQEpseLEELRGKNESLTVRLHET 293
Cdd:TIGR02169  686 LKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQ------LEQEEEKLKER---LEELEEDLSSLEQEIENV 756

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  294 LKQCQNLKTEKNQMDRKISQLSEENGDLsfKVREFANHLQQLQGAFNDLIEEHSkasqEWAEKQAHLESELSTALQDKKC 373
Cdd:TIGR02169  757 KSELKELEARIEELEEDLHKLEEALNDL--EARLSHSRIPEIQAELSKLEEEVS----RIEARLREIEQKLNRLTLEKEY 830

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  374 LEEKSEILQEKISQLEDRAAQLQGspapekgevlgdalQLDTLKQEAAKLATDNTELQARVETLECERGKQEAQLLAERG 453
Cdd:TIGR02169  831 LEKEIQELQEQRIDLKEQIKSIEK--------------EIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEA 896

                          250       260       270
                   ....*....|....*....|....*....|
gi 1958645968  454 HFEEEKRQLASLVADLQSSVSNLSQAKEEL 483
Cdd:TIGR02169  897 QLRELERKIEELEAQIEKKRKRLSELKAKL 926
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1450-1642 1.27e-06

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 53.48  E-value: 1.27e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1450 ERANLGRQFLEVELDQAREKYVQ-ELAAVRTDAETHLAEMRQEAQSTSRELEVMTAKYESAKVKVLEERQRFQEERQKLT 1528
Cdd:COG3206    171 EEARKALEFLEEQLPELRKELEEaEAALEEFRQKNGLVDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLG 250

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1529 AQVEELNKKLTESEQASRVQQ-----QKLKAFQAQGGESQQEVQCLQTQLSELQAQLSQKEQAAehyklqMEKAKTHYDA 1603
Cdd:COG3206    251 SGPDALPELLQSPVIQQLRAQlaeleAELAELSARYTPNHPDVIALRAQIAALRAQLQQEAQRI------LASLEAELEA 324

                          170       180       190
                   ....*....|....*....|....*....|....*....
gi 1958645968 1604 KKQQNQELREQLQDLEQLQKDNKELRSETERLGRELQQA 1642
Cdd:COG3206    325 LQAREASLQAQLAQLEARLAELPELEAELRRLEREVEVA 363
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
1187-1310 1.41e-06

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 53.32  E-value: 1.41e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1187 QALRaKAQDHSKAEEEWKAQVARGQQEAERkssliSSLEEEVSILNRQVLEKEGESKELKRLVVAESEKSQKLEERLRLL 1266
Cdd:COG2433    380 EALE-ELIEKELPEEEPEAEREKEHEEREL-----TEEEEEIRRLEEQVERLEAEVEELEAELEEKDERIERLERELSEA 453

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....
gi 1958645968 1267 QVEtASSSARAAERSSALREEVQSLREEVEKQRVVSENLRQELA 1310
Cdd:COG2433    454 RSE-ERREIRKDREISRLDREIERLERELEEERERIEELKRKLE 496
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1239-1667 1.46e-06

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 53.51  E-value: 1.46e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1239 EGESKEL-KRLVVAESEKSQKLEERLRL-LQVETASSSARAA----ERSSALREEVQSLREEVEKQRVV-------SENL 1305
Cdd:PRK02224   198 EKEEKDLhERLNGLESELAELDEEIERYeEQREQARETRDEAdevlEEHEERREELETLEAEIEDLRETiaetereREEL 277

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1306 RQELASQAERAEESGQELkawqekffqkEQALSALQLEHTSTQAL---VSELLPAKHLCQQLQAEQAAAEKRFREEIEQS 1382
Cdd:PRK02224   278 AEEVRDLRERLEELEEER----------DDLLAEAGLDDADAEAVearREELEDRDEELRDRLEECRVAAQAHNEEAESL 347

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1383 KQAAGGLQAELMRAQRELGELGSlrqKIVEQERAAQQLRAEKASYAEQLSMLKKAHGLLAEENRGLGERanlgRQFLEVE 1462
Cdd:PRK02224   348 REDADDLEERAEELREEAAELES---ELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDF----LEELREE 420

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1463 LDQAREKyVQELAAVRTDAETHLAEMRQ-----EAQSTSRELEvmtakyESAKVKVLEERQ----RFQEERQKLTAQVEE 1533
Cdd:PRK02224   421 RDELRER-EAELEATLRTARERVEEAEAlleagKCPECGQPVE------GSPHVETIEEDRerveELEAELEDLEEEVEE 493

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1534 LNKKLTESEQASRVQQQ------------KLKAFQAQGGESQQE-VQCLQTQLSELQAQLSQKEQAAEHYKLQMEKAKTH 1600
Cdd:PRK02224   494 VEERLERAEDLVEAEDRierleerredleELIAERRETIEEKRErAEELRERAAELEAEAEEKREAAAEAEEEAEEAREE 573

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1601 ---YDAKKQQNQELREQLQDLEQLQKDNKELRSETERLGRELQQAGLKTKEAEQACRHLTAQVRSLEAQV 1667
Cdd:PRK02224   574 vaeLNSKLAELKERIESLERIRTLLAAIADAEDEIERLREKREALAELNDERRERLAEKRERKRELEAEF 643
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 274-727 1.53e-06

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 53.49  E-value: 1.53e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  274 SELEELRGKNESLTVRLHETLKQCQNLKTEKNQMDRKISQLSEENGDLSFKVREFANHLQQLQgafnDLIEEHSKASQEW 353
Cdd:TIGR04523  145 TEIKKKEKELEKLNNKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKLELLLSNLK----KKIQKNKSLESQI 220

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  354 AEkqahLESELSTALQDKKCLEEKSEILQEKISQLEDRAAQLQGSPAPEKGEVLGDALQLDTLKQEAAKLATDNTELQAR 433
Cdd:TIGR04523  221 SE----LKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSE 296

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  434 VETLECErgKQEAQLLAERGHFEEEKRQLASLVADLQSSVSNLSQAKEELQQasqaqgaqLTAQLASLTALNATLQQQDQ 513
Cdd:TIGR04523  297 ISDLNNQ--KEQDWNKELKSELKNQEKKLEEIQNQISQNNKIISQLNEQISQ--------LKKELTNSESENSEKQRELE 366

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  514 ELTSLKEQAKKEQAQMLQTLQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEAARQDHAQQLATIVE--------- 584
Cdd:TIGR04523  367 EKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKnnseikdlt 446

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  585 ----AREASVRERDAARQQLETLEKEKDAKLESLQQQLQASNEARDTAQTSVTQAQREKAELSQKIGELHACIEAAHQEQ 660
Cdd:TIGR04523  447 nqdsVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKI 526

                          410       420       430       440       450       460       470
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1958645968  661 RQAQAHVTELEAQLKAEQQKATE------REKVVQEKVQLQEQLQALEETLKIVRGSLEEEKCRAADALKEQQ 727
Cdd:TIGR04523  527 EKLESEKKEKESKISDLEDELNKddfelkKENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKK 599
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 274-709 1.94e-06

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 53.10  E-value: 1.94e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  274 SELEELRGKNESLTVRLHETLKQCQNLKTEKNQMDRKISQLSEENGD----LSFKVREFANHLQQLQGAFNDLIEEHSKA 349
Cdd:TIGR04523  218 SQISELKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKikkqLSEKQKELEQNNKKIKELEKQLNQLKSEI 297

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  350 SQEWAEKQAHLESELSTAL--QDKKCLEEKSEILQ--EKISQLEDRAAQLQGSPAPEKGEVLGDALQLDTLKQEAAKLAT 425
Cdd:TIGR04523  298 SDLNNQKEQDWNKELKSELknQEKKLEEIQNQISQnnKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKK 377

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  426 DNTELQARVETLECERGKQEAQLLaergHFEEEKRQLASLVADLQSSVSNLSQAKEELQQASQAQGAQ---LTAQLASL- 501
Cdd:TIGR04523  378 ENQSYKQEIKNLESQINDLESKIQ----NQEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEikdLTNQDSVKe 453

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  502 ---TALNATLQQQDQELTSLKEQAKKEQAQMLQTLQE---QEQAAQGLRQQVEQLS----------SSLKLKEQQLEEAA 565
Cdd:TIGR04523  454 liiKNLDNTRESLETQLKVLSRSINKIKQNLEQKQKElksKEKELKKLNEEKKELEekvkdltkkiSSLKEKIEKLESEK 533

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  566 KEQEAARQDHAQQLATIveareasvrERDAARQQLETLEKEKDAKLESLQQQLQASNEARDTAQTSVTQAQREKAELSQK 645
Cdd:TIGR04523  534 KEKESKISDLEDELNKD---------DFELKKENLEKEIDEKNKEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKE 604

                          410       420       430       440       450       460
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1958645968  646 IGELHACIEAAHQEQRQAQAHVTELEAQLKaeqqkatereKVVQEKVQLQEQLQALEETLKIVR 709
Cdd:TIGR04523  605 IEEKEKKISSLEKELEKAKKENEKLSSIIK----------NIKSKKNKLKQEVKQIKETIKEIR 658
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
416-636 2.18e-06

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 53.10  E-value: 2.18e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  416 LKQEAAKLATDNTELQARVETLecergKQEAQLLAerghFEEEKRQLASLVADLQSSVSNLSQAKEELQQASQAQGAQLT 495
Cdd:COG3206    180 LEEQLPELRKELEEAEAALEEF-----RQKNGLVD----LSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQLG 250

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  496 AQLASLTAL--NATLQQQDQELtslkEQAKKEQAQMLQTLQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEAARQ 573
Cdd:COG3206    251 SGPDALPELlqSPVIQQLRAQL----AELEAELAELSARYTPNHPDVIALRAQIAALRAQLQQEAQRILASLEAELEALQ 326

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1958645968  574 DHAQQLATIVEAREASVRERDAARQQLETLEKEKDAKLESLQQQLQASNEARDTAQTSVTQAQ 636
Cdd:COG3206    327 AREASLQAQLAQLEARLAELPELEAELRRLEREVEVARELYESLLQRLEEARLAEALTVGNVR 389
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1115-1635 2.26e-06

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 53.12  E-value: 2.26e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1115 EVEALRAEISKLERQWQQQQQQVEGLTHSLESERACRAEqdkaLETLQGQLEEKARELGHNQAASASAQRELQALRAKAQ 1194
Cdd:PRK02224   214 ELAELDEEIERYEEQREQARETRDEADEVLEEHEERREE----LETLEAEIEDLRETIAETEREREELAEEVRDLRERLE 289

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1195 DHSKAEEEWKAQVARGQQEAERKSSLISSLEEEVSILNRQVLEKEGESKELKRLVVAESEKSQKLEERlrllqvetassS 1274
Cdd:PRK02224   290 ELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLEER-----------A 358

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1275 ARAAERSSALREEVQSLREEVEKQRVVSENLRQELASQAERAEESGQELKAWQEKFFQKEQALSALQLEHTSTQALVSEL 1354
Cdd:PRK02224   359 EELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAELEATLRTA 438

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1355 lpAKHLCQQLQAEQAAAEKRFREEIEQSKQAAGglqaelmraqrelgeLGSLRQKIVEQERAAQQLRAEKASYAEQLSML 1434
Cdd:PRK02224   439 --RERVEEAEALLEAGKCPECGQPVEGSPHVET---------------IEEDRERVEELEAELEDLEEEVEEVEERLERA 501

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1435 KKAHGLLAEENRgLGERANLGRQFLEVELDQAREKYVQeLAAVRTDAETHLAEMR-QEAQSTSRELEvmtAKYESAKVKV 1513
Cdd:PRK02224   502 EDLVEAEDRIER-LEERREDLEELIAERRETIEEKRER-AEELRERAAELEAEAEeKREAAAEAEEE---AEEAREEVAE 576

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1514 LEERQRFQEERQKLTAQVEELNKKLTESEQASRVQQQKLKAFQAQGGESQQEVQCLQTQLSELQA--------QLSQKEQ 1585
Cdd:PRK02224   577 LNSKLAELKERIESLERIRTLLAAIADAEDEIERLREKREALAELNDERRERLAEKRERKRELEAefdearieEAREDKE 656

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1958645968 1586 AAEHYKLQMEKAKTHYDAKK--------------QQNQELREQLQDLEQLQKDNKELRSETERL 1635
Cdd:PRK02224   657 RAEEYLEQVEEKLDELREERddlqaeigavenelEELEELRERREALENRVEALEALYDEAEEL 720
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 575-1072 2.58e-06

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 52.92  E-value: 2.58e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  575 HAQQLATIVEAREASVRerDAARQQLETLEKEKDAKLESLQQQLQASNEARDTAQTSVTQAQREKAElsqKIGELHACIE 654
Cdd:pfam12128  180 HIDKIAKAMHSKEGKFR--DVKSMIVAILEDDGVVPPKSRLNRQQVEHWIRDIQAIAGIMKIRPEFT---KLQQEFNTLE 254

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  655 AAHQEQRQAQAHVTELEAQLKAEQQKATEREKVVQEKV-----QLQEQLQALEETLKIVRGSLEeeKCRAA-DALKEQQR 728
Cdd:pfam12128  255 SAELRLSHLHFGYKSDETLIASRQEERQETSAELNQLLrtlddQWKEKRDELNGELSAADAAVA--KDRSElEALEDQHG 332

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  729 HATEMEAETRHLmeqreqEQKELEQEKAERKGLEARLQQLEEAHQAETEALRHELAGATaaqhgaeserEQLLREVESWQ 808
Cdd:pfam12128  333 AFLDADIETAAA------DQEQLPSWQSELENLEERLKALTGKHQDVTAKYNRRRSKIK----------EQNNRDIAGIK 396

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  809 KRVEARQQEEARYGAMFQEQLMALKGEhgkigQEEQKEAGEIHGEGQTGQQQSQLAQLHACLAKALQQVQEKEARAQKLl 888
Cdd:pfam12128  397 DKLAKIREARDRQLAVAEDDLQALESE-----LREQLEAGKLEFNEEEYRLKSRLGELKLRLNQATATPELLLQLENFD- 470

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  889 DDLSALREKMAATNKEVACLKALVLKAG-----------------EQQAAASHELKEP--PRAG-------NQESDWEEE 942
Cdd:pfam12128  471 ERIERAREEQEAANAEVERLQSELRQARkrrdqasealrqasrrlEERQSALDELELQlfPQAGtllhflrKEAPDWEQS 550

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  943 QAR-------------------------PLGSTQAALKAVQR-EAEQMGGELERLRAALMQSQGQQQEVRGQQEREVARL 996
Cdd:pfam12128  551 IGKvispellhrtdldpevwdgsvggelNLYGVKLDLKRIDVpEWAASEEELRERLDKAEEALQSAREKQAAAEEQLVQA 630

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1958645968  997 TQERGQAQADLAQEKAAKAELEMRLQNTLNEQRVEFAALQEALThamTEKEGKDQELAKLREQEAAQISELKALQQ 1072
Cdd:pfam12128  631 NGELEKASREETFARTALKNARLDLRRLFDEKQSEKDKKNKALA---ERKDSANERLNSLEAQLKQLDKKHQAWLE 703
mukB PRK04863
chromosome partition protein MukB;
1442-1672 2.73e-06

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 53.04  E-value: 2.73e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1442 AEENRGLGERANLGRQflevELDQAREKyvqelaavRTDAETHLAEMRQEAQSTSRELEVMTAKYESAK--VKVLEERQR 1519
Cdd:PRK04863   278 ANERRVHLEEALELRR----ELYTSRRQ--------LAAEQYRLVEMARELAELNEAESDLEQDYQAASdhLNLVQTALR 345

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1520 FQEERQKLTAQVEELNKKLTESEQASRVQQQKLKAFQAQGGESQQEVQCLQTQLSELQ----------AQLSQKEQAAEH 1589
Cdd:PRK04863   346 QQEKIERYQADLEELEERLEEQNEVVEEADEQQEENEARAEAAEEEVDELKSQLADYQqaldvqqtraIQYQQAVQALER 425

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1590 YK-------LQMEKAKTHYDAKKQQNQELREQLQDLEQLQKDNKELRSETERLGRELQQAGLKTkEAEQACRHLTAQVRS 1662
Cdd:PRK04863   426 AKqlcglpdLTADNAEDWLEEFQAKEQEATEELLSLEQKLSVAQAAHSQFEQAYQLVRKIAGEV-SRSEAWDVARELLRR 504

                          250
                   ....*....|
gi 1958645968 1663 LEAQVAHADQ 1672
Cdd:PRK04863   505 LREQRHLAEQ 514
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
990-1540 3.13e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 52.61  E-value: 3.13e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  990 EREVARLTQERGQAQA-DLAQEKAAKAELEMRLQNTLNEQRvEFAALQEALTHAMTEKEGKDQELAKLREQEAAQISELK 1068
Cdd:COG4913    248 REQIELLEPIRELAERyAAARERLAELEYLRAALRLWFAQR-RLELLEAELEELRAELARLEAELERLEARLDALREELD 326

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1069 ALQQTLEelkkkekehptggargedasgdgpgsqlhtpgktEAPGPEVEALRAEISKLERQWQQQQQQveglthsleser 1148
Cdd:COG4913    327 ELEAQIR----------------------------------GNGGDRLEQLEREIERLERELEERERR------------ 360

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1149 acRAEQDKALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQDhskAEEEWKAQVARGQQEAERKSSLISSLEEEV 1228
Cdd:COG4913    361 --RARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEE---ALAEAEAALRDLRRELRELEAEIASLERRK 435

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1229 S------ILNRQVLEKE-----------GESKELK-------------------RLVVAESEKSQ--------KLEERLR 1264
Cdd:COG4913    436 SniparlLALRDALAEAlgldeaelpfvGELIEVRpeeerwrgaiervlggfalTLLVPPEHYAAalrwvnrlHLRGRLV 515

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1265 LLQVETASSSARAAERSS-ALREEVQS--------LREEVEKQRVV-----SENLRQE--------LASQAERAEESGQE 1322
Cdd:COG4913    516 YERVRTGLPDPERPRLDPdSLAGKLDFkphpfrawLEAELGRRFDYvcvdsPEELRRHpraitragQVKGNGTRHEKDDR 595

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1323 LKAWQEKFF---------QKEQALSALQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKRFREEIEqskqaAGGLQAEL 1393
Cdd:COG4913    596 RRIRSRYVLgfdnraklaALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEID-----VASAEREI 670

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1394 MRAQRELGELGSLRQKIVEQERAAQQLRAEKASYAEQLSMLKKAHGLLAEEnrglgeranlgRQFLEVELDQAREKYVQE 1473
Cdd:COG4913    671 AELEAELERLDASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKE-----------LEQAEEELDELQDRLEAA 739

                          570       580       590       600       610       620
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1958645968 1474 LAAVRTDAETHLAEMRQEAQSTSRELEVmtakyesakvkvleeRQRFQEERQKLTAQVEELNKKLTE 1540
Cdd:COG4913    740 EDLARLELRALLEERFAAALGDAVEREL---------------RENLEERIDALRARLNRAEEELER 791
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 218-1068 3.59e-06

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 52.28  E-value: 3.59e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  218 KKQLADERNNRDELELELSESLKLLTEKDAQIAMMQQRIDHLALLNEKQAASPQEPSELEELRGKNESLTVRLHETLKQC 297
Cdd:pfam02463  180 EETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQE 259

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  298 QNLKTEKNQ--------MDRKISQLSEENGDLSFKVREFANHLQQLQGAFNDLIEEHSKASQEWAEKQAHLESELSTALQ 369
Cdd:pfam02463  260 IEKEEEKLAqvlkenkeEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEE 339

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  370 DKKCLEEKSEILQEKISQLEDRAAQLQgspapEKGEVLGDALQLDTLKQEAAKLATDNTELQARVEtlecERGKQEAQLL 449
Cdd:pfam02463  340 LEKELKELEIKREAEEEEEEELEKLQE-----KLEQLEEELLAKKKLESERLSSAAKLKEEELELK----SEEEKEAQLL 410

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  450 AERghfeeeKRQLASLVADLQSSVSNLSQAKEELQQASQAQGAQLTAQLASLTALNATLQQQDQELTSLKEQAKKEQAQM 529
Cdd:pfam02463  411 LEL------ARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQE 484

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  530 LQTLQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEAARQDHAQQLATIVEARE-----ASVRERDAARQQLETLE 604
Cdd:pfam02463  485 QLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKvaistAVIVEVSATADEVEERQ 564

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  605 KEKDAKLESLQQQLQASNEARDTAQTSVTQAQREKAELSQKIGELHACIEAAHQEQRQAQAHVTELEAQLKAEQQKATER 684
Cdd:pfam02463  565 KLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAK 644

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  685 EKVVQEKVQLQEQLQALEETLKIVRGSLEEEKCRAADALKEQQRHATEMEAETRHLMEQREQEQKELEQEKAE--RKGLE 762
Cdd:pfam02463  645 ESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLeaEELLA 724

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  763 ARLQQLEEAHQAETEALRHELAGATAaqhgAESEREQLLREVESWQKRVEARQQEEARYGAMFQEQLMALKGEHGKIGQE 842
Cdd:pfam02463  725 DRVQEAQDKINEELKLLKQKIDEEEE----EEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQE 800

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  843 EQKEAGEIHGEGQTGQQQsQLAQLHACLAKALQQVQEKEARAQKLLDDLSALREKMAATNKEVACLKALVLKAGEQQAAA 922
Cdd:pfam02463  801 EELRALEEELKEEAELLE-EEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEEL 879

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  923 SHELKEPPRAGNQESDWEEEQARPLGSTQ--AALKAVQREAEQMggelERLRAALMQSQGQQQEVRGQQEREVARLTQER 1000
Cdd:pfam02463  880 EEQKLKDELESKEEKEKEEKKELEEESQKlnLLEEKENEIEERI----KEEAEILLKYEEEPEELLLEEADEKEKEENNK 955

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1958645968 1001 GQAQADLAQEKAAKAELEmrlqNTLNEQRVEFAALQEALTHAMTEKEGKDQELAKLREQEAAQISELK 1068
Cdd:pfam02463  956 EEEEERNKRLLLAKEELG----KVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQRL 1019
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 367-560 3.71e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 51.69  E-value: 3.71e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  367 ALQDKKCLEEKSEILQEKISQLEDRAAQLQGspapEKGEVLGdalQLDTLKQEAAKLATDNTELQARVETLECERGKQEA 446
Cdd:COG4942     18 QADAAAEAEAELEQLQQEIAELEKELAALKK----EEKALLK---QLAALERRIAALARRIRALEQELAALEAELAELEK 90

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  447 QLLAERGHFEEEKRQLASLVADLQS-----------SVSNLSQAK------EELQQASQAQGAQLTAQLASLTALNATLQ 509
Cdd:COG4942     91 EIAELRAELEAQKEELAELLRALYRlgrqpplalllSPEDFLDAVrrlqylKYLAPARREQAEELRADLAELAALRAELE 170

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1958645968  510 QQDQELTSLKEQAKKEQAQMLQTLQEQEQAAQGLRQQVEQLSSSLKLKEQQ 560
Cdd:COG4942    171 AERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQE 221
46 PHA02562
endonuclease subunit; Provisional
 306-536 4.14e-06

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 51.94  E-value: 4.14e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  306 QMDR----KISQLSEENGDLSFKVrefaNHLQQLQGAFNDLIEE-HSKASQEWAEKQAHLESELSTALQDKKCLEEKSEI 380
Cdd:PHA02562   167 EMDKlnkdKIRELNQQIQTLDMKI----DHIQQQIKTYNKNIEEqRKKNGENIARKQNKYDELVEEAKTIKAEIEELTDE 242

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  381 LQEKISQLEDRAAQLQgspapekgevlgdalqldtlkqeaaKLATDNTELQARVETLecergKQEAQLLAERGH------ 454
Cdd:PHA02562   243 LLNLVMDIEDPSAALN-------------------------KLNTAAAKIKSKIEQF-----QKVIKMYEKGGVcptctq 292

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  455 -FEEEKRQLASL---VADLQSSVSNLSQAKEELqqasQAQGAQLTAQLASLTALNATLQQQDQELTSLKEQAKKEQAQMl 530
Cdd:PHA02562   293 qISEGPDRITKIkdkLKELQHSLEKLDTAIDEL----EEIMDEFNEQSKKLLELKNKISTNKQSLITLVDKAKKVKAAI- 367


                   ....*.
gi 1958645968  531 QTLQEQ 536
Cdd:PHA02562   368 EELQAE 373
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1395-1637 4.61e-06

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 52.22  E-value: 4.61e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1395 RAQRELGELGSLRQKIVEQERAAQQLRAEKASYAEQLSMLKKAhgllaEENRGLGERANLGRQFLEVELDQARekyVQEL 1474
Cdd:COG4913    229 ALVEHFDDLERAHEALEDAREQIELLEPIRELAERYAAARERL-----AELEYLRAALRLWFAQRRLELLEAE---LEEL 300

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1475 AAVRTDAETHLAEMRQEAQSTSRELEVMTAKYESAKVKVLEErqrfqeerqkLTAQVEELNKKLTESEQASRVQQQKLKA 1554
Cdd:COG4913    301 RAELARLEAELERLEARLDALREELDELEAQIRGNGGDRLEQ----------LEREIERLERELEERERRRARLEALLAA 370

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1555 FQAQGGESQQEVQCLQTQLSELQAQLSQKEQAAEhyklqmekakthydakkqqnQELREQLQDLEQLQKDNKELRSETER 1634
Cdd:COG4913    371 LGLPLPASAEEFAALRAEAAALLEALEEELEALE--------------------EALAEAEAALRDLRRELRELEAEIAS 430


                   ...
gi 1958645968 1635 LGR 1637
Cdd:COG4913    431 LER 433
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 858-1073 5.49e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 50.92  E-value: 5.49e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  858 QQQSQLAQLHACLAKALQQVQEKEARAQKLLDDLSALREKMAATNKEVACLKALVLKAGEQQAAASHElkeppragnqes 937
Cdd:COG4942     24 EAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKE------------ 91

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  938 dwEEEQARPLGSTQAALKAVQREAEQMGgELERLRAALMQSQGQQQEVRGQQEREVARLTQERGQAQADLAQEKAAKAEL 1017
Cdd:COG4942     92 --IAELRAELEAQKEELAELLRALYRLG-RQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAE 168

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1958645968 1018 EMRLQNTLNEQRVEFAALQEALTHAMTEKEGKDQELAKLREQEAAQISELKALQQT 1073
Cdd:COG4942    169 LEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEE 224
mukB PRK04863
chromosome partition protein MukB;
1402-1679 6.08e-06

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 51.88  E-value: 6.08e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1402 ELGSLRQKIVEQERAAQQLRAEKASYAEQLSMLKKAHGLLaeeNRGLGERANLGRQFLEVELDQARE---------KYVQ 1472
Cdd:PRK04863   838 ELRQLNRRRVELERALADHESQEQQQRSQLEQAKEGLSAL---NRLLPRLNLLADETLADRVEEIREqldeaeeakRFVQ 914

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1473 ELAAVRTDAETHLAEMRQEAQstsrELEVMTAKYESAkvkvlEERQRFQEERQKLTAQV---------EELNKKLTESEQ 1543
Cdd:PRK04863   915 QHGNALAQLEPIVSVLQSDPE----QFEQLKQDYQQA-----QQTQRDAKQQAFALTEVvqrrahfsyEDAAEMLAKNSD 985

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1544 ASRVQQQKLKAFQAQGGESQQevqclqtQLSELQAQLSQKEQAaehyklqMEKAKTHYDAKKQQNQELREQLQDLEQLQK 1623
Cdd:PRK04863   986 LNEKLRQRLEQAEQERTRARE-------QLRQAQAQLAQYNQV-------LASLKSSYDAKRQMLQELKQELQDLGVPAD 1051

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1958645968 1624 DNKELRSETERlgRELQQAglkTKEAEQACRHLTAQVRSLEAQVAHADQQLRDLGK 1679
Cdd:PRK04863  1052 SGAEERARARR--DELHAR---LSANRSRRNQLEKQLTFCEAEMDNLTKKLRKLER 1102
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
457-1039 6.19e-06

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 51.58  E-value: 6.19e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  457 EEKRQLASL----VADLQSSVSN-LSQAKEELQQASQAQgaqLTAQLASLTALNATLQQQDQELTSLKEQAKKEQAQMLQ 531
Cdd:PRK02224   165 EEYRERASDarlgVERVLSDQRGsLDQLKAQIEEKEEKD---LHERLNGLESELAELDEEIERYEEQREQARETRDEADE 241

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  532 TLQEQEQAAQGLrQQVEQLSSSLKLKEQQLEEAAKEQEAARQDHAQQLATIVEAREASVRE-------RDAARQQLETLE 604
Cdd:PRK02224   242 VLEEHEERREEL-ETLEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAEaglddadAEAVEARREELE 320

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  605 KEKDAKLESLQQQ---LQASNEARDTAQTSVTQAQREKAELSQKIGELHACIEAAHQEQRQAQAHVTELEAQLKAEQQK- 680
Cdd:PRK02224   321 DRDEELRDRLEECrvaAQAHNEEAESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERf 400

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  681 ---ATEREKVVQEKVQLQEQLQALEETLKIVRGSLEEekcrAADALKEQQRHATEMEAETRHLMEQREQEQKELEQEKAE 757
Cdd:PRK02224   401 gdaPVDLGNAEDFLEELREERDELREREAELEATLRT----ARERVEEAEALLEAGKCPECGQPVEGSPHVETIEEDRER 476

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  758 RKGLEARLQQLEEahqaETEALRHELAGATAAQHgAESEREQLLREVESWQKRVEARQQeearygamfqeqlmalkgehg 837
Cdd:PRK02224   477 VEELEAELEDLEE----EVEEVEERLERAEDLVE-AEDRIERLEERREDLEELIAERRE--------------------- 530

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  838 kiGQEEQKEageihgegqtgqqqsQLAQLHACLAKALQQVQEKEARAQKLLDDLSALREKMAATNKEVACLK-------- 909
Cdd:PRK02224   531 --TIEEKRE---------------RAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKeriesler 593

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  910 -ALVLKAGEQQAAASHELKEPPRAGNQESDWEEEQARPLGSTQAALkavqrEAEQMGGELERLRAALMQSQGQQQEVrgq 988
Cdd:PRK02224   594 iRTLLAAIADAEDEIERLREKREALAELNDERRERLAEKRERKREL-----EAEFDEARIEEAREDKERAEEYLEQV--- 665

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1958645968  989 qEREVARLTQERGQAQADLAQEKAAKAELEmrlqnTLNEQRVEFAALQEAL 1039
Cdd:PRK02224   666 -EEKLDELREERDDLQAEIGAVENELEELE-----ELRERREALENRVEAL 710
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
625-1070 6.52e-06

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 51.58  E-value: 6.52e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  625 RDTAQTSVTQAQREKAELSQKigELHACIEAAHQEQRQAQAHVTELEAQLKAEQQKATEREKVVQEKVQLQEQLQALEET 704
Cdd:PRK02224   182 LSDQRGSLDQLKAQIEEKEEK--DLHERLNGLESELAELDEEIERYEEQREQARETRDEADEVLEEHEERREELETLEAE 259

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  705 LKIVRGSLEE---EKCRAADALKEQQRHATEMEAETRHLMEQREQEQkeleqekAERKGLEARLQQLEEAHQAETEALRH 781
Cdd:PRK02224   260 IEDLRETIAEterEREELAEEVRDLRERLEELEEERDDLLAEAGLDD-------ADAEAVEARREELEDRDEELRDRLEE 332

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  782 ELAGATAAQHGAESEREQLLR-EVESWQKRVEARQQEEArygamfqeqlmalkgehgkigQEEQKEAGEiHGEGQTGQQQ 860
Cdd:PRK02224   333 CRVAAQAHNEEAESLREDADDlEERAEELREEAAELESE---------------------LEEAREAVE-DRREEIEELE 390

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  861 SQLAQLHACLAKALQQVQEKEARAQKLLDDLSALREKMAATNKEVACLKALVLKAGEQQAAAS-----HELKEPPRAGNQ 935
Cdd:PRK02224   391 EEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAELEATLRTARERVEEAEALLEAGKcpecgQPVEGSPHVETI 470

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  936 ESDweEEQARPLGSTQAALKAVQREAEQmggELERLRAAlmqsqgQQQEVRGQQEREVARLTQERGQAQADLAQEKAAKA 1015
Cdd:PRK02224   471 EED--RERVEELEAELEDLEEEVEEVEE---RLERAEDL------VEAEDRIERLEERREDLEELIAERRETIEEKRERA 539

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1958645968 1016 ElemRLQNTLNEQRVEFAALQEALTHAMTEKEGKDQELAKLREQEAAQISELKAL 1070
Cdd:PRK02224   540 E---ELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLAELKERIESL 591
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 252-774 7.18e-06

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 51.33  E-value: 7.18e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  252 MQQRIDHLALLNEKQAASPQEPSELEELRGKNESLTVRLHETLKQCQNLKTEKNQMDRKIS----QLSEENGDLSFKVRE 327
Cdd:pfam01576    7 MQAKEEELQKVKERQQKAESELKELEKKHQQLCEEKNALQEQLQAETELCAEAEEMRARLAarkqELEEILHELESRLEE 86

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  328 FANHLQQLQGafndlieEHSKASQEWAEKQAHLESELST--ALQ-DKKCLEEKSEILQEKISQLEDRAAQLQGSPAPEKG 404
Cdd:pfam01576   87 EEERSQQLQN-------EKKKMQQHIQDLEEQLDEEEAArqKLQlEKVTTEAKIKKLEEDILLLEDQNSKLSKERKLLEE 159

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  405 EVLGDALQLDTLKQEAAKLATDNTELQARVETLECERGKQEAQllaeRGHFEEEKRQLASLVADLQSSVSNLSQAKEELQ 484
Cdd:pfam01576  160 RISEFTSNLAEEEEKAKSLSKLKNKHEAMISDLEERLKKEEKG----RQELEKAKRKLEGESTDLQEQIAELQAQIAELR 235

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  485 QASQAQGAQLTAQLASL---TALNATLQQQDQELTS----LKEQAKKEQAQM--------------------LQTLQEQE 537
Cdd:pfam01576  236 AQLAKKEEELQAALARLeeeTAQKNNALKKIRELEAqiseLQEDLESERAARnkaekqrrdlgeelealkteLEDTLDTT 315

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  538 QAAQGLRQQVEQLSSSLKLK-EQQLEEAAKEQEAARQDHAQQLATIVEAREASVRER---DAARQQLETLEKEKDAKLES 613
Cdd:pfam01576  316 AAQQELRSKREQEVTELKKAlEEETRSHEAQLQEMRQKHTQALEELTEQLEQAKRNKanlEKAKQALESENAELQAELRT 395

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  614 LQQQLQASNEARDTA-------QTSVTQAQREKAELSQKIGELHACIEAAHQEQRQAQAHVTELEAQLKAEQQKATEREK 686
Cdd:pfam01576  396 LQQAKQDSEHKRKKLegqlqelQARLSESERQRAELAEKLSKLQSELESVSSLLNEAEGKNIKLSKDVSSLESQLQDTQE 475

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  687 VVQE----KVQLQEQLQALEETLKIVRGSLEEEKCRAADALKEQQRHATEMEAETRHLMEQREQEQKELEQEKAERKGLE 762
Cdd:pfam01576  476 LLQEetrqKLNLSTRLRQLEDERNSLQEQLEEEEEAKRNVERQLSTLQAQLSDMKKKLEEDAGTLEALEEGKKRLQRELE 555

                          570
                   ....*....|..
gi 1958645968  763 ARLQQLEEAHQA 774
Cdd:pfam01576  556 ALTQQLEEKAAA 567
CALCOCO1 pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
 685-1041 7.33e-06

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 51.05  E-value: 7.33e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  685 EKVVQEKVQLQEQLQALEETLKIVRGSLEEEKCRAADALKEQQRHATEMEAETRHLMEQREQEQKELEQEKAERKGLEAR 764
Cdd:pfam07888   37 EECLQERAELLQAQEAANRQREKEKERYKRDREQWERQRRELESRVAELKEELRQSREKHEELEEKYKELSASSEELSEE 116

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  765 LQQLEEAhQAETEALRHELAGATAAQHGAESEREQLLREVESWQKRVEARQQEEARYGAMFQEQLMALKGEHGKIGQEEQ 844
Cdd:pfam07888  117 KDALLAQ-RAAHEARIRELEEDIKTLTQRVLERETELERMKERAKKAGAQRKEEEAERKQLQAKLQQTEEELRSLSKEFQ 195

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  845 KEAGEIhgeGQTGQQQSQLAQLHACLAKALQQVQEKEARAQKLLDDLSALREKMAATNKEVACLKALVLKAGEQQAAASH 924
Cdd:pfam07888  196 ELRNSL---AQRDTQVLQLQDTITTLTQKLTTAHRKEAENEALLEELRSLQERLNASERKVEGLGEELSSMAAQRDRTQA 272

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  925 ELK----EPPRAGNQESD----WEEEQARPLGSTQAALKAVQREAEQmggeLERLRAALMQSQGQQQEVRGQQEREVARL 996
Cdd:pfam07888  273 ELHqarlQAAQLTLQLADaslaLREGRARWAQERETLQQSAEADKDR----IEKLSAELQRLEERLQEERMEREKLEVEL 348

                          330       340       350       360
                   ....*....|....*....|....*....|....*....|....*
gi 1958645968  997 TQERGQAQADLAQEKAAKAELEMRLQNTLNEQRVEFAALQEALTH 1041
Cdd:pfam07888  349 GREKDCNRVQLSESRRELQELKASLRVAQKEKEQLQAEKQELLEY 393
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 605-820 7.70e-06

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 50.53  E-value: 7.70e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  605 KEKDAKLESLQQQLQASNEARDTAQTSVTQAQREKAELSQKIGELHACIEAAHQEQRQAQAHVTELEAQLKAEQQKATER 684
Cdd:COG4942     23 AEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQ 102

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  685 EKVVQEKVQLQEQLQALEETLKIVRGSLEEEKCRAADALKEQQRhatemeaETRHLMEQREQEQKELEQEKAERKGLEAR 764
Cdd:COG4942    103 KEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAP-------ARREQAEELRADLAELAALRAELEAERAE 175

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1958645968  765 LQQLEEAHQAETEALRHELAGATAAQHGAESEREQLLREVESWQKRVEARQQEEAR 820
Cdd:COG4942    176 LEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIAR 231
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
841-1323 1.02e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 51.07  E-value: 1.02e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  841 QEEQKEAGEIHGEGQTGQQQSQLAQLHACLAKALQQVQEKEARAQKLLDDLSALREKMAATNKEVACLKALVLKAGEQQA 920
Cdd:COG4913    261 AERYAAARERLAELEYLRAALRLWFAQRRLELLEAELEELRAELARLEAELERLEARLDALREELDELEAQIRGNGGDRL 340

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  921 AashELKEPPRAGNQEsdwEEEQARPLGSTQAALKAVQREAEQMGGELERLRAALMQSQGQQQEVRGQQEREVARLTQER 1000
Cdd:COG4913    341 E---QLEREIERLERE---LEERERRRARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALAEAEAAL 414

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1001 GQAQADLAQEKAAKAELEMRlQNTLNEqrvEFAALQEALTHAMTEKEGKDQ---ELAKLREQEAA-QISELKAL------ 1070
Cdd:COG4913    415 RDLRRELRELEAEIASLERR-KSNIPA---RLLALRDALAEALGLDEAELPfvgELIEVRPEEERwRGAIERVLggfalt 490

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1071 -----QQTLEELKKKEKEHPTGGARGEDASGDGPGSQLHTPGK-------TEAPGPEVEALRAEISK------------L 1126
Cdd:COG4913    491 llvppEHYAAALRWVNRLHLRGRLVYERVRTGLPDPERPRLDPdslagklDFKPHPFRAWLEAELGRrfdyvcvdspeeL 570

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1127 ERqwQQQQQQVEGLTHSLESERACRAEQD------------KALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQ 1194
Cdd:COG4913    571 RR--HPRAITRAGQVKGNGTRHEKDDRRRirsryvlgfdnrAKLAALEAELAELEEELAEAEERLEALEAELDALQERRE 648

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1195 DHSKAEEEWKAQ--VARGQQEAERKSSLISSLEE---EVSILNRQVLEKEGESKELKRLVVAESEKSQKLEERLRLLQVE 1269
Cdd:COG4913    649 ALQRLAEYSWDEidVASAEREIAELEAELERLDAssdDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEE 728

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1958645968 1270 TASSSARAAERSSALREEVQSLREEV-------EKQRVVSENLRQELASQAERAEESGQEL 1323
Cdd:COG4913    729 LDELQDRLEAAEDLARLELRALLEERfaaalgdAVERELRENLEERIDALRARLNRAEEEL 789
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
573-803 1.13e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 50.68  E-value: 1.13e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  573 QDHAQQLATIVEAREASVRERDAARQQLETLEKEKDA---KLESLQQQLQASNEARDTAQTS--VTQAQREKAELSQKIG 647
Cdd:COG4913    606 FDNRAKLAALEAELAELEEELAEAEERLEALEAELDAlqeRREALQRLAEYSWDEIDVASAEreIAELEAELERLDASSD 685

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  648 ELHACIEAAHQEQRQAQAHVTELEAQLKAEQQKATEREKVVQEKVQLQEQLQALEETLKIVRGSLEEEKCRAADALKEQQ 727
Cdd:COG4913    686 DLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGDAVER 765

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1958645968  728 RHATEMEAETRHLmeqreqeqkeleqeKAERKGLEARLQQLEEAHQAETEALRHELAGATAAQHGAESEREQLLRE 803
Cdd:COG4913    766 ELRENLEERIDAL--------------RARLNRAEEELERAMRAFNREWPAETADLDADLESLPEYLALLDRLEED 827
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 1215-1710 1.49e-05

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 50.22  E-value: 1.49e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1215 ERKSSLISSLEEEVSILNRQVLEKEGESKELKRlvvAESEKSQKLEERLRLLQVETASSSARAAERSSALREEVQSLREE 1294
Cdd:pfam12128  247 QQEFNTLESAELRLSHLHFGYKSDETLIASRQE---ERQETSAELNQLLRTLDDQWKEKRDELNGELSAADAAVAKDRSE 323

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1295 VEkqrVVSENLRQELASQAERAEESGQELKAWQEKFFQKEQALSALQLEHTSTQA-------LVSELLPAK--------- 1358
Cdd:pfam12128  324 LE---ALEDQHGAFLDADIETAAADQEQLPSWQSELENLEERLKALTGKHQDVTAkynrrrsKIKEQNNRDiagikdkla 400

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1359 ------------------HLCQQLQAEQAAAEKRFREEIEQSKQAAGGLQAELMRAQRELGELGSLRQKIVEQERAAQQL 1420
Cdd:pfam12128  401 kireardrqlavaeddlqALESELREQLEAGKLEFNEEEYRLKSRLGELKLRLNQATATPELLLQLENFDERIERAREEQ 480

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1421 RAEKASYAEQLSMLKKAHGLLAEENRGLGeRANLGRQFLEVELDQAREKYVQE----LAAVRTDA---ETHLAEMRQEAQ 1493
Cdd:pfam12128  481 EAANAEVERLQSELRQARKRRDQASEALR-QASRRLEERQSALDELELQLFPQagtlLHFLRKEApdwEQSIGKVISPEL 559

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1494 STSRELE-VMTAKYESAKVKVLEERQRFQE-ERQKLTAQVEELNKKLTESEQASRVQQQKLKAFQAQGGESQQEVQCLQT 1571
Cdd:pfam12128  560 LHRTDLDpEVWDGSVGGELNLYGVKLDLKRiDVPEWAASEEELRERLDKAEEALQSAREKQAAAEEQLVQANGELEKASR 639

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1572 QLSEL-----QAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQELREQLQDLEQLQKDNKELRSETERLGRELQQAGLKT 1646
Cdd:pfam12128  640 EETFArtalkNARLDLRRLFDEKQSEKDKKNKALAERKDSANERLNSLEAQLKQLDKKHQAWLEEQKEQKREARTEKQAY 719

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1958645968 1647 KEAEQACR--HLTAQVRSLEAQVAHADQQLRDLGKFQVATDALKSREPQVKPQLDLSIDSLDLSLE 1710
Cdd:pfam12128  720 WQVVEGALdaQLALLKAAIAARRSGAKAELKALETWYKRDLASLGVDPDVIAKLKREIRTLERKIE 785
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 411-733 1.54e-05

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 50.34  E-value: 1.54e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  411 LQLDTLKQEAAKLATDNTELQARVETLECERGKQ---------EAQLLAERGHFEEEKRQLASLVADLQSSVSNLSQAKE 481
Cdd:COG3096    792 AERDELAEQYAKASFDVQKLQRLHQAFSQFVGGHlavafapdpEAELAALRQRRSELERELAQHRAQEQQLRQQLDQLKE 871

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  482 ELQQ--------------ASQAQGAQLTAQLASLTALNATLQQQDQELTSLKEQakkeqaqmLQTLQEQEQAAQGLRQQV 547
Cdd:COG3096    872 QLQLlnkllpqanlladeTLADRLEELREELDAAQEAQAFIQQHGKALAQLEPL--------VAVLQSDPEQFEQLQADY 943

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  548 EQLSSSLKLKEQQLEEaakeqeaarqdhaqqLATIVEAREASVRErDAARQQLETLEKEkdaklESLQQQLQASNEARDT 627
Cdd:COG3096    944 LQAKEQQRRLKQQIFA---------------LSEVVQRRPHFSYE-DAVGLLGENSDLN-----EKLRARLEQAEEARRE 1002

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  628 AQTSVTQAQREKAELSQKIGELHACIEAAHQEQRQAQAHVTELEAQL--KAEQQKATEREKVVQEKVQLQEQLQALEETL 705
Cdd:COG3096   1003 AREQLRQAQAQYSQYNQVLASLKSSRDAKQQTLQELEQELEELGVQAdaEAEERARIRRDELHEELSQNRSRRSQLEKQL 1082

                          330       340       350
                   ....*....|....*....|....*....|
gi 1958645968  706 KIVRGSLEE--EKCRAADALKEQQRHATEM 733
Cdd:COG3096   1083 TRCEAEMDSlqKRLRKAERDYKQEREQVVQ 1112
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 1442-1677 1.60e-05

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 50.34  E-value: 1.60e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1442 AEENRGLGERANLGRQflevELDQAREKyvqelaavRTDAETHLAEMRQEAQSTSRELEVMTAKYESAK--VKVLEERQR 1519
Cdd:COG3096    277 ANERRELSERALELRR----ELFGARRQ--------LAEEQYRLVEMARELEELSARESDLEQDYQAASdhLNLVQTALR 344

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1520 FQEERQKLTAQVEELNKKLTESEQASRVQQQKLKAFQAQGGESQQEVQCLQTQLSELQA----------QLSQKEQAAEH 1589
Cdd:COG3096    345 QQEKIERYQEDLEELTERLEEQEEVVEEAAEQLAEAEARLEAAEEEVDSLKSQLADYQQaldvqqtraiQYQQAVQALEK 424

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1590 YK-------LQMEKAKTHYDAKKQQNQELREQLQDLEQLQKDNKELRSETERLGRELQQ--AGLKTKEAEQACRHLTAQV 1660
Cdd:COG3096    425 ARalcglpdLTPENAEDYLAAFRAKEQQATEEVLELEQKLSVADAARRQFEKAYELVCKiaGEVERSQAWQTARELLRRY 504

                          250       260
                   ....*....|....*....|
gi 1958645968 1661 RSLEAQVAHADQ---QLRDL 1677
Cdd:COG3096    505 RSQQALAQRLQQlraQLAEL 524
PRK10246 PRK10246
exonuclease subunit SbcC; Provisional
 595-1063 1.60e-05

exonuclease subunit SbcC; Provisional


Pssm-ID: 182330 [Multi-domain]  Cd Length: 1047  Bit Score: 50.18  E-value: 1.60e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  595 AARQQLETLEKE-------KDAKLESLQQQLQASNEARDTAQTSVTQAQREKAELSQKiGELHACIEAAHQEQRQAQAHV 667
Cdd:PRK10246   195 SARTELEKLQAQasgvallTPEQVQSLTASLQVLTDEEKQLLTAQQQQQQSLNWLTRL-DELQQEASRRQQALQQALAAE 273

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  668 TELEAQLkAEQQKATEREKVVQEKVQLQEQLQALEETlkivRGSLEEEKCR--AADALKEQQRHATEMEAETRhlmeqre 745
Cdd:PRK10246   274 EKAQPQL-AALSLAQPARQLRPHWERIQEQSAALAHT----RQQIEEVNTRlqSTMALRARIRHHAAKQSAEL------- 341

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  746 qeqkeleqeKAERKGLEARLQQLEEAHQaeteaLRHELAGATAAQHGAESEREQLLRevesWQKRVEARQQeearygamf 825
Cdd:PRK10246   342 ---------QAQQQSLNTWLAEHDRFRQ-----WNNELAGWRAQFSQQTSDREQLRQ----WQQQLTHAEQ--------- 394

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  826 qeQLMALKGEHGKIGQEEQKEAGEIHGEGQTGQQ-----QSQLAQLHACLAKALQQVQEKEARAQKLLDDLSALREKMAA 900
Cdd:PRK10246   395 --KLNALPAITLTLTADEVAAALAQHAEQRPLRQrlvalHGQIVPQQKRLAQLQVAIQNVTQEQTQRNAALNEMRQRYKE 472

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  901 TNKEVACLKALV-----LKAGEQQAAASHELKEPPRAGNQESDW-EEEQARPLGSTQAALKAVQREAEQMGGELERLRAA 974
Cdd:PRK10246   473 KTQQLADVKTICeqearIKDLEAQRAQLQAGQPCPLCGSTSHPAvEAYQALEPGVNQSRLDALEKEVKKLGEEGAALRGQ 552

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  975 LMQSQGQQQevrgQQEREVARLTQErgqAQADLAQEKAAKAELEMRLQntlneqrvefaaLQEALTHAMTEKEGKDQELA 1054
Cdd:PRK10246   553 LDALTKQLQ----RDESEAQSLRQE---EQALTQQWQAVCASLNITLQ------------PQDDIQPWLDAQEEHERQLR 613


                   ....*....
gi 1958645968 1055 KLREQEAAQ 1063
Cdd:PRK10246   614 LLSQRHELQ 622
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 826-1022 1.66e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 49.38  E-value: 1.66e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  826 QEQLMALKGEHGKIGQEEQKEAGEIHG-EGQTGQQQSQLAQLHACLAKALQQVQEKEARAQKLLDDLSALREKMAATNKE 904
Cdd:COG4942     26 EAELEQLQQEIAELEKELAALKKEEKAlLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEE 105

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  905 VACLKALVLKAGEQQAAASHELKEPPRAG-------NQESDWEEEQARPLGSTQAALKAVQREAEQMGGELERLRAALMQ 977
Cdd:COG4942    106 LAELLRALYRLGRQPPLALLLSPEDFLDAvrrlqylKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAELEE 185

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*
gi 1958645968  978 SQGQQQEVRGQQEREVARLTQERGQAQADLAQEKAAKAELEMRLQ 1022
Cdd:COG4942    186 ERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIA 230
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 1147-1676 1.79e-05

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 50.17  E-value: 1.79e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1147 ERACRAEQD-KALETLQGQLEEKARELGHNQAASASAQRELQALRAK-AQDHSKAEEEWKAQVARGQQEAERKSSLISS- 1223
Cdd:pfam01576   19 ERQQKAESElKELEKKHQQLCEEKNALQEQLQAETELCAEAEEMRARlAARKQELEEILHELESRLEEEEERSQQLQNEk 98

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1224 --LEEEVSILNRQVLEKEGESKELKRLVVAESEKSQKLEERLRLLQVETASSSARAAERSSALREEVQSLREEVEKQRVV 1301
Cdd:pfam01576   99 kkMQQHIQDLEEQLDEEEAARQKLQLEKVTTEAKIKKLEEDILLLEDQNSKLSKERKLLEERISEFTSNLAEEEEKAKSL 178

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1302 S------ENLRQELASQAERAEESGQELKAWQEKFfqkEQALSALQLEHTSTQALVSELlpaKHLCQQLQAEQAAAEKRF 1375
Cdd:pfam01576  179 SklknkhEAMISDLEERLKKEEKGRQELEKAKRKL---EGESTDLQEQIAELQAQIAEL---RAQLAKKEEELQAALARL 252

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1376 REEIEQSKQAAgglqaelmRAQRELGELGSLRQKIVEQERAAQQlRAEKasyaeqlsmlkkahgllaeENRGLGERANLG 1455
Cdd:pfam01576  253 EEETAQKNNAL--------KKIRELEAQISELQEDLESERAARN-KAEK-------------------QRRDLGEELEAL 304

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1456 RQFLEVELD------QAREKYVQELAAVR-------TDAETHLAEMRQEAQSTSRELEVMTAKYESAKVKVLEERQRFQE 1522
Cdd:pfam01576  305 KTELEDTLDttaaqqELRSKREQEVTELKkaleeetRSHEAQLQEMRQKHTQALEELTEQLEQAKRNKANLEKAKQALES 384

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1523 ERQKLTAQVEELNKKLTESEQASRVQQQKLKAFQAQGGESQQEVQCLQTQLSELQAQLSQKEQAAEHYKLQMEKAKTHYD 1602
Cdd:pfam01576  385 ENAELQAELRTLQQAKQDSEHKRKKLEGQLQELQARLSESERQRAELAEKLSKLQSELESVSSLLNEAEGKNIKLSKDVS 464

                          490       500       510       520       530       540       550
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1958645968 1603 AKKQQNQELREQLQD--LEQLQKDNKELRSETERLGRELQQaglktKEAEQACRHLTAQVRSLEAQVAHADQQLRD 1676
Cdd:pfam01576  465 SLESQLQDTQELLQEetRQKLNLSTRLRQLEDERNSLQEQL-----EEEEEAKRNVERQLSTLQAQLSDMKKKLEE 535
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 213-535 2.04e-05

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 50.06  E-value: 2.04e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  213 QMRRLKKQLADERNNRDELELELSESLKLLTEKDAQIAMMQQRIDHLALLNEK-QAASPQEPSELEELRGKNESLTVRLH 291
Cdd:TIGR02168  692 KIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQlEERIAQLSKELTELEAEIEELEERLE 771

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  292 ETLKQCQNLKTEKNQMDRKISQLSEENGDLSFKVREFANHLQQLQGAFNDLIEEHSKASQEWAEKQAHLESelstalqdk 371
Cdd:TIGR02168  772 EAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLED--------- 842

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  372 kcLEEKSEILQEKISQLEDRAAQLQGSPAPEKGEVLGDALQLDTLKQEAAKLATDNTELQARVETLECERGKQEAQLLAE 451
Cdd:TIGR02168  843 --LEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEEL 920

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  452 RGHFEEEKRQLASLVADLQSSVSNLS--------------QAKEELQQASQAQGAQLTAQLASLTALNAT-------LQQ 510
Cdd:TIGR02168  921 REKLAQLELRLEGLEVRIDNLQERLSeeysltleeaealeNKIEDDEEEARRRLKRLENKIKELGPVNLAaieeyeeLKE 1000

                          330       340
                   ....*....|....*....|....*
gi 1958645968  511 QDQELTSLKEQAKKEQAQMLQTLQE 535
Cdd:TIGR02168 1001 RYDFLTAQKEDLTEAKETLEEAIEE 1025
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
534-714 2.10e-05

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 49.63  E-value: 2.10e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  534 QEQEQAAQGLRQQVEQLSSSLKLKEQQLEE-----AAKEQEAARQDHAQQLATIVEAREASVRERDAARQQLETLEKE-- 606
Cdd:COG3206    171 EEARKALEFLEEQLPELRKELEEAEAALEEfrqknGLVDLSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQlg 250

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  607 ----------KDAKLESLQQQLQASNEARDTAQT-------SVTQAQREKAELSQKI-GELHACIEAAHQEQRQAQAHVT 668
Cdd:COG3206    251 sgpdalpellQSPVIQQLRAQLAELEAELAELSArytpnhpDVIALRAQIAALRAQLqQEAQRILASLEAELEALQAREA 330

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*.
gi 1958645968  669 ELEAQLKAEQQKATEREKVVQEKVQLQEQLQALEETLKIVRGSLEE 714
Cdd:COG3206    331 SLQAQLAQLEARLAELPELEAELRRLEREVEVARELYESLLQRLEE 376
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 1144-1674 2.30e-05

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 49.79  E-value: 2.30e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1144 LESERACRAEQDKALETLQGqleekarELGHNQAASASAQRELQALRAKAQdhsKAEEEWKAQVARGQQEAERKSSLISS 1223
Cdd:pfam01576  196 LKKEEKGRQELEKAKRKLEG-------ESTDLQEQIAELQAQIAELRAQLA---KKEEELQAALARLEEETAQKNNALKK 265

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1224 LEEevsiLNRQVLEKEgESKELKRLVVAESEKSQK-LEERLRLLQVE---TASSSARAAERSSALREEVQSLREEVEKQR 1299
Cdd:pfam01576  266 IRE----LEAQISELQ-EDLESERAARNKAEKQRRdLGEELEALKTEledTLDTTAAQQELRSKREQEVTELKKALEEET 340

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1300 VVSENLRQELASQAERA-EESGQELKAWQEKFFQKEQALSALQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKRFREE 1378
Cdd:pfam01576  341 RSHEAQLQEMRQKHTQAlEELTEQLEQAKRNKANLEKAKQALESENAELQAELRTLQQAKQDSEHKRKKLEGQLQELQAR 420

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1379 IEQSKQAAGGLQAELMRAQRELGELGSLrqkIVEQERAAQQLRAEKASYAEQLsmlKKAHGLLAEENRglgERANLGRQF 1458
Cdd:pfam01576  421 LSESERQRAELAEKLSKLQSELESVSSL---LNEAEGKNIKLSKDVSSLESQL---QDTQELLQEETR---QKLNLSTRL 491

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1459 LEVELDQAR-EKYVQELAAVRTDAETHLAEMRQEAQSTSRELEVMTAKYESAKvkvlEERQRFQEERQKLTAQVEELNKK 1537
Cdd:pfam01576  492 RQLEDERNSlQEQLEEEEEAKRNVERQLSTLQAQLSDMKKKLEEDAGTLEALE----EGKKRLQRELEALTQQLEEKAAA 567

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1538 LTESEQASRVQQQKLKAFQAQGGESQQEVQCLQTQLSELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQ----NQELRE 1613
Cdd:pfam01576  568 YDKLEKTKNRLQQELDDLLVDLDHQRQLVSNLEKKQKKFDQMLAEEKAISARYAEERDRAEAEAREKETRalslARALEE 647

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1958645968 1614 QLQDLEQLQKDNKELRSETERLGRELQQAGLKTKEAEQACRHLTAQVRSLEAQVAHADQQL 1674
Cdd:pfam01576  648 ALEAKEELERTNKQLRAEMEDLVSSKDDVGKNVHELERSKRALEQQVEEMKTQLEELEDEL 708
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
1514-1689 2.35e-05

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 49.38  E-value: 2.35e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1514 LEERQRFQEERQKLTAQVEELNKKLTESEQAsrvqQQKLKAFQAQGGESQQEVQCLQTQLS--ELQAQLSQKEQAAEHYK 1591
Cdd:COG4717     70 LKELKELEEELKEAEEKEEEYAELQEELEEL----EEELEELEAELEELREELEKLEKLLQllPLYQELEALEAELAELP 145

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1592 LQMEKAKTHYDAKKQQNQELREQLQDLEQLQKD-NKELRSETERLGRELQQAGLKTKEAEQACRHLTAQVRSLEAQVAHA 1670
Cdd:COG4717    146 ERLEELEERLEELRELEEELEELEAELAELQEElEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEEL 225

                          170
                   ....*....|....*....
gi 1958645968 1671 DQQLRDLGKFQVATDALKS 1689
Cdd:COG4717    226 EEELEQLENELEAAALEER 244
PRK10929 PRK10929
putative mechanosensitive channel protein; Provisional
 1144-1340 2.52e-05

putative mechanosensitive channel protein; Provisional


Pssm-ID: 236798 [Multi-domain]  Cd Length: 1109  Bit Score: 49.67  E-value: 2.52e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1144 LESERACRAEQDKA------LETLQGQLEEKARELghnqaasASAQRELQALRAKAQDHSKAeeewkaQVARGQQEAERK 1217
Cdd:PRK10929   119 LEKSRQAQQEQDRAreisdsLSQLPQQQTEARRQL-------NEIERRLQTLGTPNTPLAQA------QLTALQAESAAL 185

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1218 SSLISSLE-EEVSILNRQvlekegeskELKRLVVAESEK-SQKLEERLRLLQVETASSSARAAE----RSSALREEVQSL 1291
Cdd:PRK10929   186 KALVDELElAQLSANNRQ---------ELARLRSELAKKrSQQLDAYLQALRNQLNSQRQREAEraleSTELLAEQSGDL 256

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1292 REEVEKQRVVSENLRQELASQAERAEE-SGQELKAWQEKfFQKEQALSAL 1340
Cdd:PRK10929   257 PKSIVAQFKINRELSQALNQQAQRMDLiASQQRQAASQT-LQVRQALNTL 305
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
204-726 2.63e-05

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 49.68  E-value: 2.63e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  204 GDILQTPQFQMRRLKKQLADERNNRDELElelseslklltEKDAQIAMMQQRIDHLAL----LNEKQAASPQEPSELEEL 279
Cdd:PRK03918   168 GEVIKEIKRRIERLEKFIKRTENIEELIK-----------EKEKELEEVLREINEISSelpeLREELEKLEKEVKELEEL 236

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  280 RGKNESLTVRLHETLKQCQNLKTEKNQMDRKISQLSEENGDLSFKVREfanhLQQLQG------AFNDLIEEHSKASQEW 353
Cdd:PRK03918   237 KEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKE----LKELKEkaeeyiKLSEFYEEYLDELREI 312

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  354 AEKQAHLESELST---ALQDKKCLEEKSEILQEKISQLEDRAAQLQgspapEKGEVLGDALQLDTLKQEAAKLATDNTEL 430
Cdd:PRK03918   313 EKRLSRLEEEINGieeRIKELEEKEERLEELKKKLKELEKRLEELE-----ERHELYEEAKAKKEELERLKKRLTGLTPE 387

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  431 QARVETLECERGKQEAQLlaERGHFEEEKRQLASLVADLQSSVSNLSQAK---------------EELQQASQAQGAQLT 495
Cdd:PRK03918   388 KLEKELEELEKAKEEIEE--EISKITARIGELKKEIKELKKAIEELKKAKgkcpvcgrelteehrKELLEEYTAELKRIE 465

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  496 AQLASLTALNATLQQQDQELTS-----------------LKEQAKKEQAQMLQTLQEQEQAAQGLRQQVEQLSSSLKLKE 558
Cdd:PRK03918   466 KELKEIEEKERKLRKELRELEKvlkkeseliklkelaeqLKELEEKLKKYNLEELEKKAEEYEKLKEKLIKLKGEIKSLK 545

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  559 QQLEEAakeqeaarQDHAQQLATIVEAREASVRERDAARQQLETL----EKEKDAKLESLQQQLQASNEARDtaqtsvtq 634
Cdd:PRK03918   546 KELEKL--------EELKKKLAELEKKLDELEEELAELLKELEELgfesVEELEERLKELEPFYNEYLELKD-------- 609

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  635 AQREKAELSQKIGELHACIEAAHQEQRQAQAHVTELEAQLKAEQQKATERE--KVVQEKVQLQEQLQALEETLKIVRGSL 712
Cdd:PRK03918   610 AEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEEEyeELREEYLELSRELAGLRAELEELEKRR 689

                          570
                   ....*....|....
gi 1958645968  713 EEEKcRAADALKEQ 726
Cdd:PRK03918   690 EEIK-KTLEKLKEE 702
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1517-1688 3.08e-05

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 49.24  E-value: 3.08e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1517 RQRFQEERQKLTAQVEELNKKLTESEQAsrvqqqkLKAFQA---------QGGESQQEVQCLQTQLSELQAQLSQKEQAA 1587
Cdd:COG3206    170 REEARKALEFLEEQLPELRKELEEAEAA-------LEEFRQknglvdlseEAKLLLQQLSELESQLAEARAELAEAEARL 242

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1588 EHYKLQMEKAKTH---------YDAKKQQNQELREQLQDLEQLQKDN----KELRSETERLGRELQQAGLKTK-EAEQAC 1653
Cdd:COG3206    243 AALRAQLGSGPDAlpellqspvIQQLRAQLAELEAELAELSARYTPNhpdvIALRAQIAALRAQLQQEAQRILaSLEAEL 322

                          170       180       190
                   ....*....|....*....|....*....|....*
gi 1958645968 1654 RHLTAQVRSLEAQVAHADQQLRDLGKFQVATDALK 1688
Cdd:COG3206    323 EALQAREASLQAQLAQLEARLAELPELEAELRRLE 357
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 1115-1699 3.23e-05

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 49.20  E-value: 3.23e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1115 EVEALRAEISKLERQWQQQQQQVEGLTHSLESERACRAEQD--KALETLQGQLEEKARELGHNQAASASAQRELQALRAK 1192
Cdd:TIGR00618  268 RIEELRAQEAVLEETQERINRARKAAPLAAHIKAVTQIEQQaqRIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQRRLL 347

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1193 AQDHSKAEE---------EWKAQVARGQQEAER-------------KSSLISSLEEEVSILNRQVLEKEGESKELKRLVV 1250
Cdd:TIGR00618  348 QTLHSQEIHirdahevatSIREISCQQHTLTQHihtlqqqkttltqKLQSLCKELDILQREQATIDTRTSAFRDLQGQLA 427

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1251 AESEKSQKLEERLRLLQVETASSSARAAERSSALREEVQSLREEVEKQRVVSENLRQElasqAERAEESGQELKAWQEKF 1330
Cdd:TIGR00618  428 HAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQSLKEREQQLQTKEQIHLQE----TRKKAVVLARLLELQEEP 503

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1331 FQKEQALSALQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKRFREEIEQSKQAAgGLQAELMRAQRELGELGSLRQKI 1410
Cdd:TIGR00618  504 CPLCGSCIHPNPARQDIDNPGPLTRRMQRGEQTYAQLETSEEDVYHQLTSERKQRA-SLKEQMQEIQQSFSILTQCDNRS 582

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1411 VEQERAAQQLRAEKASYAEQLSMLKKAhglLAEENRGLGERAN--LGRQFLEVELDQAREKYVQELAAVRTDAETHLAEM 1488
Cdd:TIGR00618  583 KEDIPNLQNITVRLQDLTEKLSEAEDM---LACEQHALLRKLQpeQDLQDVRLHLQQCSQELALKLTALHALQLTLTQER 659

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1489 RQEAQSTSRELEVMTAKYESAKVKVLEERQRFQEERQKLTAQVEELNKKLTESEQASRVQQQKL-KAFQAQGGESQQEVQ 1567
Cdd:TIGR00618  660 VREHALSIRVLPKELLASRQLALQKMQSEKEQLTYWKEMLAQCQTLLRELETHIEEYDREFNEIeNASSSLGSDLAARED 739

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1568 CLQTQLSELQAQLSQKEQAAEHYKLQMEKAKThydAKKQQNQELREQLQDLEQLQKDNKELRSETERLGRELQQaglKTK 1647
Cdd:TIGR00618  740 ALNQSLKELMHQARTVLKARTEAHFNNNEEVT---AALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQ---EIP 813

                          570       580       590       600       610
                   ....*....|....*....|....*....|....*....|....*....|..
gi 1958645968 1648 EAEQAcrhLTAQVRSLEAQVAHADQQLRDLGKFQVATDALKSREPQVKPQLD 1699
Cdd:TIGR00618  814 SDEDI---LNLQCETLVQEEEQFLSRLEEKSATLGEITHQLLKYEECSKQLA 862
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1164-1400 3.44e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 48.61  E-value: 3.44e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1164 QLEEKARELGHNQAASASAQRELQALRAKAQDHSKAEEEWKAQVARGQQEAERKSSLISSLEEEVSILNRQVLEKEGESK 1243
Cdd:COG4942     21 AAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELE 100

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1244 ELKRLVVAESEKSQKLEERLRLLQVETASSSARAAERSSALREEVQSLREEVEKQRVVsenlRQELASQAERAEESGQEL 1323
Cdd:COG4942    101 AQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRAD----LAELAALRAELEAERAEL 176

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1958645968 1324 KAWQEKFFQKEQALSALQLEHTSTQALVSEllpakhlcqqlqaeqaaAEKRFREEIEQSKQAAGGLQAELMRAQREL 1400
Cdd:COG4942    177 EALLAELEEERAALEALKAERQKLLARLEK-----------------ELAELAAELAELQQEAEELEALIARLEAEA 236
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
412-638 3.71e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 49.14  E-value: 3.71e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  412 QLDTLKQEAAKLATDNTELQARVETLEcergkQEAQLLAERghfeeekRQLASLVADLQSSVSNLSQAKEELQQasqaqg 491
Cdd:COG4913    611 KLAALEAELAELEEELAEAEERLEALE-----AELDALQER-------REALQRLAEYSWDEIDVASAEREIAE------ 672

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  492 aqLTAQLASLTALNATLQQqdqeltslkeqakkeqaqmlqtLQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEAA 571
Cdd:COG4913    673 --LEAELERLDASSDDLAA----------------------LEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEE 728

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1958645968  572 RQDHAQQLATIVEAREASVRERDAARQQLETLEKEKDAKLESLQQQLQASNEARDTAQTSVTQAQRE 638
Cdd:COG4913    729 LDELQDRLEAAEDLARLELRALLEERFAAALGDAVERELRENLEERIDALRARLNRAEEELERAMRA 795
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
275-803 4.17e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 48.76  E-value: 4.17e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  275 ELEELRGKNESLT--VRLHETLKQCQNLKTEKNQMDRKIS--QLSEENGDLSFKVREFANHLQQLQGAFNDLIEEHSKAS 350
Cdd:COG4913    243 ALEDAREQIELLEpiRELAERYAAARERLAELEYLRAALRlwFAQRRLELLEAELEELRAELARLEAELERLEARLDALR 322

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  351 QEWAE-KQAHLES---ELSTALQDKKCLEEKSEILQEKISQLEDRAAQLqGSPAPEkgevlgDALQLDTLKQEAAKLATD 426
Cdd:COG4913    323 EELDElEAQIRGNggdRLEQLEREIERLERELEERERRRARLEALLAAL-GLPLPA------SAEEFAALRAEAAALLEA 395

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  427 NTELQARVETLECERGKQEAQLlaerghfEEEKRQLASLVADLQSSVSNLSQakeelqqasqaqgaqltAQLASLTALNA 506
Cdd:COG4913    396 LEEELEALEEALAEAEAALRDL-------RRELRELEAEIASLERRKSNIPA-----------------RLLALRDALAE 451

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  507 TLQQQDQELTSLKE--QAKKEQA------------QMLQTLQEQEQAAQGLRqQVEQLSSSLKLKEQQLEEAAKEQEAAR 572
Cdd:COG4913    452 ALGLDEAELPFVGEliEVRPEEErwrgaiervlggFALTLLVPPEHYAAALR-WVNRLHLRGRLVYERVRTGLPDPERPR 530

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  573 qDHAQQLATIVEAREASVRE-------RDAARQQLETLE---------------------KEKD---------------- 608
Cdd:COG4913    531 -LDPDSLAGKLDFKPHPFRAwleaelgRRFDYVCVDSPEelrrhpraitragqvkgngtrHEKDdrrrirsryvlgfdnr 609

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  609 AKLESLQQQLQASNEARDTAQTSVTQAQREKAELSQKIGELHACIEAAHQEQ--RQAQAHVTELEAQLKAEQQKATEREK 686
Cdd:COG4913    610 AKLAALEAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEIdvASAEREIAELEAELERLDASSDDLAA 689

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  687 VVQEKVQLQEQLQALEETLKIVRGSLEEEKCRAADALKEQQRHATEMEAetrhlmeqreqeqKELEQEKAERKGLEARLQ 766
Cdd:COG4913    690 LEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEA-------------AEDLARLELRALLEERFA 756

                          570       580       590
                   ....*....|....*....|....*....|....*....
gi 1958645968  767 QL--EEAHQAETEALRHELAGATAAQHGAESEREQLLRE 803
Cdd:COG4913    757 AAlgDAVERELRENLEERIDALRARLNRAEEELERAMRA 795
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1503-1679 4.78e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 48.91  E-value: 4.78e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1503 TAKYESAKVKVLEERQRFQEERQKLTAQVEELNKKL----TESEQASRVQQQKLKAFQAQGGESQQEVQCLQTQLSELQA 1578
Cdd:TIGR02169  165 VAEFDRKKEKALEELEEVEENIERLDLIIDEKRQQLerlrREREKAERYQALLKEKREYEGYELLKEKEALERQKEAIER 244

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1579 QLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQELREQLQDLE-----QLQKDNKELRSETERLGRELQQAGLKTKEAEQAC 1653
Cdd:TIGR02169  245 QLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGeeeqlRVKEKIGELEAEIASLERSIAEKERELEDAEERL 324

                          170       180
                   ....*....|....*....|....*.
gi 1958645968 1654 RHLTAQVRSLEAQVAHADQQLRDLGK 1679
Cdd:TIGR02169  325 AKLEAEIDKLLAEIEELEREIEEERK 350
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1512-1690 4.91e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.84  E-value: 4.91e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1512 KVLEERQRFQEERQKLTAQVEELNKKLTESEQASRVQQQKLKAFQAQGGESQQEVQCLQTQLSELQAQLSQ-----KEQA 1586
Cdd:COG4942     31 QLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAqkeelAELL 110

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1587 AEHYKL----------------QMEKAKTHYDAKKQQNQELREQLQ-DLEQLQKDNKELRSETERLGRELQQAGLKTKEA 1649
Cdd:COG4942    111 RALYRLgrqpplalllspedflDAVRRLQYLKYLAPARREQAEELRaDLAELAALRAELEAERAELEALLAELEEERAAL 190

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|.
gi 1958645968 1650 EQACRHLTAQVRSLEAQVAHADQQLRDLGKFQVATDALKSR 1690
Cdd:COG4942    191 EALKAERQKLLARLEKELAELAAELAELQQEAEELEALIAR 231
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 494-1072 6.08e-05

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 48.25  E-value: 6.08e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  494 LTAQLASLTALNATLQQQDQELTSLKEQAKKEQAQMLQTLQEQEQAAQGLRQQVEQLSSSLKLKEQQLEeaakeqeaarq 573
Cdd:pfam01576   45 LQEQLQAETELCAEAEEMRARLAARKQELEEILHELESRLEEEEERSQQLQNEKKKMQQHIQDLEEQLD----------- 113

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  574 dhaqqlativeareasvrERDAARQQLETLEKEKDAKLESLQQQLQASNEARDTAQTSVTQAQREKAELSQKIGELHACI 653
Cdd:pfam01576  114 ------------------EEEAARQKLQLEKVTTEAKIKKLEEDILLLEDQNSKLSKERKLLEERISEFTSNLAEEEEKA 175

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  654 EAAHQEQRQAQAHVTELEAQLKAEQQKATEREKVVQ----EKVQLQEQ---LQALEETLKIVRGSLEEEKCRAADALKEQ 726
Cdd:pfam01576  176 KSLSKLKNKHEAMISDLEERLKKEEKGRQELEKAKRklegESTDLQEQiaeLQAQIAELRAQLAKKEEELQAALARLEEE 255

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  727 QRHATEMEAETRHLMEQREQEQKELEQEKAERKGLEARLQQLEEahqaETEALRHELA---GATAAQHGAESEREQ---- 799
Cdd:pfam01576  256 TAQKNNALKKIRELEAQISELQEDLESERAARNKAEKQRRDLGE----ELEALKTELEdtlDTTAAQQELRSKREQevte 331

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  800 LLREVESWQKRVEARQQE-EARYGAMFQ------EQLMALKGEHGKIGQEEQKEAGEIHGEGQTGQQ------------Q 860
Cdd:pfam01576  332 LKKALEEETRSHEAQLQEmRQKHTQALEelteqlEQAKRNKANLEKAKQALESENAELQAELRTLQQakqdsehkrkklE 411

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  861 SQLAQLHACLAKALQQVQEKEARAQKLLDD-------LSALREKMAATNKEVACLKALVLKAGE-------QQAAASHEL 926
Cdd:pfam01576  412 GQLQELQARLSESERQRAELAEKLSKLQSElesvsslLNEAEGKNIKLSKDVSSLESQLQDTQEllqeetrQKLNLSTRL 491

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  927 K--EPPRAGNQESDWEEEQA-----RPLGSTQAALKAVQREAEQMGGELERLRAALMQSQGQQQEVRGQQEREVA---RL 996
Cdd:pfam01576  492 RqlEDERNSLQEQLEEEEEAkrnveRQLSTLQAQLSDMKKKLEEDAGTLEALEEGKKRLQRELEALTQQLEEKAAaydKL 571

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1958645968  997 TQERGQAQADLAQEKAAKAELEMRLQNTLNEQRVEFAALQEALTHAMTEKEGKDQELAKLREQEAAQISELKALQQ 1072
Cdd:pfam01576  572 EKTKNRLQQELDDLLVDLDHQRQLVSNLEKKQKKFDQMLAEEKAISARYAEERDRAEAEAREKETRALSLARALEE 647
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 1137-1699 6.18e-05

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 48.25  E-value: 6.18e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1137 VEGLTHSLESERACRAEQDKALETLQGQLEEKARELGHNQAASASAQR-------ELQALRAKAQDHSKAEEEWKAQVAR 1209
Cdd:pfam01576  358 LEELTEQLEQAKRNKANLEKAKQALESENAELQAELRTLQQAKQDSEHkrkklegQLQELQARLSESERQRAELAEKLSK 437

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1210 GQQEAERKSSLISSLEEEVSILNRQVLEKEGESKELKRLVVAESEKSQKLEERLRLLQVETASSSARAAERSSAlREEVQ 1289
Cdd:pfam01576  438 LQSELESVSSLLNEAEGKNIKLSKDVSSLESQLQDTQELLQEETRQKLNLSTRLRQLEDERNSLQEQLEEEEEA-KRNVE 516

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1290 SLREEVEKQRVVSENLRQELASQAERAEES----GQELKAWQEKFFQKEQALSALQLEHTSTQALVSELLPAKHLCQQLQ 1365
Cdd:pfam01576  517 RQLSTLQAQLSDMKKKLEEDAGTLEALEEGkkrlQRELEALTQQLEEKAAAYDKLEKTKNRLQQELDDLLVDLDHQRQLV 596

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1366 AEQAAAEKRFREEIEQSKQAAGGLQAELMRAQRELGE-----------LGSLRQKIVEQERAAQQLRAEK---------- 1424
Cdd:pfam01576  597 SNLEKKQKKFDQMLAEEKAISARYAEERDRAEAEAREketralslaraLEEALEAKEELERTNKQLRAEMedlvsskddv 676

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1425 ASYAEQLSMLKKAHGLLAEENRGLGER-------ANLGRQFLEVELDQAREKYVQELAAVRTDAEthlaEMRQEAQSTSR 1497
Cdd:pfam01576  677 GKNVHELERSKRALEQQVEEMKTQLEEledelqaTEDAKLRLEVNMQALKAQFERDLQARDEQGE----EKRRQLVKQVR 752

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1498 ELEVMTAKYESAKVKVLEERQRFQEERQKLTAQVEELNKKLTESEQASRVQQQKLKAFQ--------------AQGGESQ 1563
Cdd:pfam01576  753 ELEAELEDERKQRAQAVAAKKKLELDLKELEAQIDAANKGREEAVKQLKKLQAQMKDLQreleearasrdeilAQSKESE 832

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1564 QEVQCLQTQLSELQAQLSQKEQA-----AEHYKLQMEKA------------KTHYDAKKQQ-NQELREQLQDLEQLQKDN 1625
Cdd:pfam01576  833 KKLKNLEAELLQLQEDLAASERArrqaqQERDELADEIAsgasgksalqdeKRRLEARIAQlEEELEEEQSNTELLNDRL 912

                          570       580       590       600       610       620       630
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 1958645968 1626 KELRSETERLGRELQQAGLKTKEAEQACRHLTAQVRSLEAQVAHADQQLRdlGKFQVATDALKSREPQVKPQLD 1699
Cdd:pfam01576  913 RKSTLQVEQLTTELAAERSTSQKSESARQQLERQNKELKAKLQEMEGTVK--SKFKSSIAALEAKIAQLEEQLE 984
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 525-705 6.38e-05

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 46.46  E-value: 6.38e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  525 EQAQMLQTLQEQEQAAQGLRQQVEQLSSSLKLKEQQLeeaakeqeaarqdhaQQLATIVEAREASVRERDAARQQLETLE 604
Cdd:COG1579      4 EDLRALLDLQELDSELDRLEHRLKELPAELAELEDEL---------------AALEARLEAAKTELEDLEKEIKRLELEI 68

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  605 KEKDAKLESLQQQLQA--SNEARDTAQTSVTQAQREKAELSQKIGELHACIEAAHQEQRQAQAHVTELEAQLKAEQQK-A 681
Cdd:COG1579     69 EEVEARIKKYEEQLGNvrNNKEYEALQKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAElD 148

                          170       180
                   ....*....|....*....|....
gi 1958645968  682 TEREKVVQEKVQLQEQLQALEETL 705
Cdd:COG1579    149 EELAELEAELEELEAEREELAAKI 172
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 1140-1677 6.45e-05

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 48.25  E-value: 6.45e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1140 LTHSLESERACRAEQDKALETLQGQLEEKARELGHNQAASAsAQRELQALRAKAQDHSKA--EEEWKAQVARGQQEAERK 1217
Cdd:pfam01576  276 LQEDLESERAARNKAEKQRRDLGEELEALKTELEDTLDTTA-AQQELRSKREQEVTELKKalEEETRSHEAQLQEMRQKH 354

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1218 SSLISSLEEEVSILNR---------QVLEKEGE--SKELKRLVVAESE---KSQKLEERLRLLQV---ETASSSARAAER 1280
Cdd:pfam01576  355 TQALEELTEQLEQAKRnkanlekakQALESENAelQAELRTLQQAKQDsehKRKKLEGQLQELQArlsESERQRAELAEK 434

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1281 SSALREEVQSLR---EEVEKQRVVSENLRQELASQAERAEESGQELKAWQEKFFQKeqaLSALQLEHTSTQALVSELLPA 1357
Cdd:pfam01576  435 LSKLQSELESVSsllNEAEGKNIKLSKDVSSLESQLQDTQELLQEETRQKLNLSTR---LRQLEDERNSLQEQLEEEEEA 511

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1358 KHLCQQLQAEQAAAEKRFREEIEQSKQAAGGLQAELMRAQRELgelgslrqkiveqERAAQQLRAEKASYAEqlsmLKKA 1437
Cdd:pfam01576  512 KRNVERQLSTLQAQLSDMKKKLEEDAGTLEALEEGKKRLQREL-------------EALTQQLEEKAAAYDK----LEKT 574

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1438 HGLLAEENRGLGERANLGRQFLEvELDQAREKYVQELAAVRTdAETHLAEMRQEAQSTSRELEVMTAKYESAKVKVLEER 1517
Cdd:pfam01576  575 KNRLQQELDDLLVDLDHQRQLVS-NLEKKQKKFDQMLAEEKA-ISARYAEERDRAEAEAREKETRALSLARALEEALEAK 652

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1518 QRFQEERQKLTAQVEEL-------NKKLTESEQASRVQQQklkafqaqggesqqEVQCLQTQLSELQAQLSQKEQAAEHY 1590
Cdd:pfam01576  653 EELERTNKQLRAEMEDLvsskddvGKNVHELERSKRALEQ--------------QVEEMKTQLEELEDELQATEDAKLRL 718

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1591 KLQMEKAKTHYDAKKQQNQELREQLQdlEQLQKDNKELRSETERLGRELQQAGLKTKEAEQACRHLTAQVRSLEAQVAHA 1670
Cdd:pfam01576  719 EVNMQALKAQFERDLQARDEQGEEKR--RQLVKQVRELEAELEDERKQRAQAVAAKKKLELDLKELEAQIDAANKGREEA 796


                   ....*..
gi 1958645968 1671 DQQLRDL 1677
Cdd:pfam01576  797 VKQLKKL 803
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1276-1678 6.46e-05

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 48.14  E-value: 6.46e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1276 RAAERSSALREEVQSLREEVEKQRVVSENLRQELASQAERAEESGQELKAWQEKFFQKEQALSALQLEHTSTQALVSELL 1355
Cdd:PRK03918   162 NAYKNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIE 241

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1356 PAKhlcqQLQAEQAAAEKRFREEIEQSKQAAGGLQAELMRAQRELGELGSLRQKIVEQERaaqqLRAEKASYAEQLSMLK 1435
Cdd:PRK03918   242 ELE----KELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKEKAEEYIK----LSEFYEEYLDELREIE 313

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1436 KAHGLLAEENRGLGER-ANLGRQFLEV-ELDQAREKYVQELAAVRTDAETH------LAEMRQ-EAQSTSRELEVMTAKY 1506
Cdd:PRK03918   314 KRLSRLEEEINGIEERiKELEEKEERLeELKKKLKELEKRLEELEERHELYeeakakKEELERlKKRLTGLTPEKLEKEL 393

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1507 ES---AKVKVLEERQRFQEERQKLTAQVEELNKKLTESEQASRV------------QQQKLKAFQAQGGESQQEVQCLQT 1571
Cdd:PRK03918   394 EElekAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKcpvcgrelteehRKELLEEYTAELKRIEKELKEIEE 473

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1572 QLSELQAQLSQKEQaaehyKLQMEKAKTHYDAKKQQNQELREQLQ--DLEQLQKDNKELRSETERL-GRELQQAGLKT-- 1646
Cdd:PRK03918   474 KERKLRKELRELEK-----VLKKESELIKLKELAEQLKELEEKLKkyNLEELEKKAEEYEKLKEKLiKLKGEIKSLKKel 548

                          410       420       430
                   ....*....|....*....|....*....|....*
gi 1958645968 1647 ---KEAEQACRHLTAQVRSLEAQVAHADQQLRDLG 1678
Cdd:PRK03918   549 eklEELKKKLAELEKKLDELEEELAELLKELEELG 583
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 338-561 6.77e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.45  E-value: 6.77e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  338 AFNDLIEEHSKASQEWAEKQAHLESELSTALQDKKCLEEKSEILQEKISQLEDRAAQLQGSPAPEKGEVLGDALQLDTLK 417
Cdd:COG4942     17 AQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELR 96

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  418 QEaakLATDNTELQARVETLECERGKQEAQLLAERGHFEEEKRQLA---SLVADLQSSVSNLSQAKEELQQASQAqgaqL 494
Cdd:COG4942     97 AE---LEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQylkYLAPARREQAEELRADLAELAALRAE----L 169

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1958645968  495 TAQLASLTALNATLQQQDQELTSLKEQAKKEQAQMLQTLQEQEQAAQGLRQQVEQLSSSLKLKEQQL 561
Cdd:COG4942    170 EAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEA 236
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1309-1558 7.98e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.45  E-value: 7.98e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1309 LASQAERAEESGQELKAWQEKFFQKEQALSALQLEHTSTQALVSELlpakhlcqqlqaeqaaaekrfREEIEQSKQAAGG 1388
Cdd:COG4942     15 AAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAAL---------------------ERRIAALARRIRA 73

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1389 LQAELMRAQRELGELGSlrqkivEQERAAQQLRAEKASYAEQLSMLKKAhgllaeenrGLGERANLGRQFLEVELDQARE 1468
Cdd:COG4942     74 LEQELAALEAELAELEK------EIAELRAELEAQKEELAELLRALYRL---------GRQPPLALLLSPEDFLDAVRRL 138

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1469 KYVQELAAVRTDAETHLAEMRQEAQSTSRELEVMTAKYESAKVKVLEERQRFQEERQKLTAQVEELNKKLTESEQASRVQ 1548
Cdd:COG4942    139 QYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAEL 218

                          250
                   ....*....|
gi 1958645968 1549 QQKLKAFQAQ 1558
Cdd:COG4942    219 QQEAEELEAL 228
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1465-1673 8.27e-05

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.07  E-value: 8.27e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1465 QAREKYVQELAAVRTDAETHLAEMRQEAQSTSRELEVMTAKYESAKVKVLEERQRFQEERQKLTAQVEELNKKLTESEQA 1544
Cdd:COG4942     37 AELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELAELLRALYRL 116

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1545 SRVQQQKLKAFQAQGGESQQEVQCLQTQLSELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQELREQLQDLEQLQKD 1624
Cdd:COG4942    117 GRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAELEEERAALEALKAE 196

                          170       180       190       200
                   ....*....|....*....|....*....|....*....|....*....
gi 1958645968 1625 NKELRSeteRLGRELQQAGLKTKEAEQACRHLTAQVRSLEAQVAHADQQ 1673
Cdd:COG4942    197 RQKLLA---RLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
PRK09039 PRK09039
peptidoglycan -binding protein;
526-686 9.52e-05

peptidoglycan -binding protein;


Pssm-ID: 181619 [Multi-domain]  Cd Length: 343  Bit Score: 46.88  E-value: 9.52e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  526 QAQMLQTLQEQEQAAQGLRQQVEQLSSSLKLKEQqleeaakeqeaarqdHAQQLATIVEAREASVRERDAARQQLETLEK 605
Cdd:PRK09039    41 QFFLSREISGKDSALDRLNSQIAELADLLSLERQ---------------GNQDLQDSVANLRASLSAAEAERSRLQALLA 105

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  606 EKDAKLESLQQQLQASNEARDTAQTSVTQAQREKAELSQKI-------GELHACIEAAHQEQRQAQAHVTELEAQLK-AE 677
Cdd:PRK09039   106 ELAGAGAAAEGRAGELAQELDSEKQVSARALAQVELLNQQIaalrrqlAALEAALDASEKRDRESQAKIADLGRRLNvAL 185


                   ....*....
gi 1958645968  678 QQKATEREK 686
Cdd:PRK09039   186 AQRVQELNR 194
PRK10929 PRK10929
putative mechanosensitive channel protein; Provisional
 265-642 9.88e-05

putative mechanosensitive channel protein; Provisional


Pssm-ID: 236798 [Multi-domain]  Cd Length: 1109  Bit Score: 47.74  E-value: 9.88e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  265 KQAASPQEPSELEELRGKNESLTVRlHETLKQCQNLKTEKNQMDRKISQLSEENGDLSFKVREFANHL------QQLQGA 338
Cdd:PRK10929    36 KAAKTPAQAEIVEALQSALNWLEER-KGSLERAKQYQQVIDNFPKLSAELRQQLNNERDEPRSVPPNMstdaleQEILQV 114

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  339 FNDLIEEHSKASQEwAEKQAHLESELSTALQDKkclEEKSEILQEKISQLedraaQLQGSPAPEKGEVlgdalQLDTLKQ 418
Cdd:PRK10929   115 SSQLLEKSRQAQQE-QDRAREISDSLSQLPQQQ---TEARRQLNEIERRL-----QTLGTPNTPLAQA-----QLTALQA 180

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  419 EAAKLatdntelQARVETLECER----GKQE-AQLLAERghFEEEKRQLASLVADLQSSVSNLSQAK--------EELQQ 485
Cdd:PRK10929   181 ESAAL-------KALVDELELAQlsanNRQElARLRSEL--AKKRSQQLDAYLQALRNQLNSQRQREaeralestELLAE 251

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  486 ASQAQGAQLTAQLASLTALNATLQQQDQELTSLKEQAKKEQAQMLQTlqeqEQAAQGLRQQVEQLSSSLKLKEQQLEeaa 565
Cdd:PRK10929   252 QSGDLPKSIVAQFKINRELSQALNQQAQRMDLIASQQRQAASQTLQV----RQALNTLREQSQWLGVSNALGEALRA--- 324

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1958645968  566 keqeaarqdhaqQLATIVEAREASVRERDAARQQLETLEKEKD-AKLESLQQQLQASNEARDTAQTSVTQAQ-REKAEL 642
Cdd:PRK10929   325 ------------QVARLPEMPKPQQLDTEMAQLRVQRLRYEDLlNKQPQLRQIRQADGQPLTAEQNRILDAQlRTQREL 391
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 614-1641 1.03e-04

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 47.48  E-value: 1.03e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  614 LQQQLQASNEARDTAQTSVTQAQREKAELSQKIGELHACIE-------AAHQEQRQAQAHVTELEAQLKAEQqkaTEREK 686
Cdd:pfam01576   45 LQEQLQAETELCAEAEEMRARLAARKQELEEILHELESRLEeeeersqQLQNEKKKMQQHIQDLEEQLDEEE---AARQK 121

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  687 VVQEKVQLQEQLQALEETLKIV---RGSLEEEKCRAADALKEQQRHATEMEAETRHLmeqreqeQKELEQEKAERKGLEA 763
Cdd:pfam01576  122 LQLEKVTTEAKIKKLEEDILLLedqNSKLSKERKLLEERISEFTSNLAEEEEKAKSL-------SKLKNKHEAMISDLEE 194

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  764 RLQQLEEAHQaETEALRHELAGATAAQHGAESEREQLLREVeswqKRVEARQQEEARYGAMFQEQLMALKGEHGKIGQEE 843
Cdd:pfam01576  195 RLKKEEKGRQ-ELEKAKRKLEGESTDLQEQIAELQAQIAEL----RAQLAKKEEELQAALARLEEETAQKNNALKKIREL 269

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  844 QkeageihgeGQTGQQQSQLAQLHACLAKALQQV----QEKEARAQKLLDDL---SALREKMAATNKEVACLKALVLKAG 916
Cdd:pfam01576  270 E---------AQISELQEDLESERAARNKAEKQRrdlgEELEALKTELEDTLdttAAQQELRSKREQEVTELKKALEEET 340

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  917 EQQAAASHELKEPPRAGNQESDWEEEQA-RPLGSTQAALKAVQREAEQMGGELERLRAALMQSQGQQQEVRGQQEREVAR 995
Cdd:pfam01576  341 RSHEAQLQEMRQKHTQALEELTEQLEQAkRNKANLEKAKQALESENAELQAELRTLQQAKQDSEHKRKKLEGQLQELQAR 420

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  996 LTQerGQAQADLAQEKAAKAELEMrlqntlneqrvefaalqEALTHAMTEKEGKDQELAKLREQEAAQiselkaLQQTLE 1075
Cdd:pfam01576  421 LSE--SERQRAELAEKLSKLQSEL-----------------ESVSSLLNEAEGKNIKLSKDVSSLESQ------LQDTQE 475

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1076 ELKKKEKEHPTGGARGEDASGDGPGSQLHTPGKTEAPgpevEALRAEISKLERQWQQQQQQVEGLTHSLESERACRAEQD 1155
Cdd:pfam01576  476 LLQEETRQKLNLSTRLRQLEDERNSLQEQLEEEEEAK----RNVERQLSTLQAQLSDMKKKLEEDAGTLEALEEGKKRLQ 551

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1156 KALETLQGQLEEKARELGHNQAASASAQRELQALRAkAQDHSK--AEEEWKAQVARGQQEAERKSsLISSLEEEVSILNR 1233
Cdd:pfam01576  552 RELEALTQQLEEKAAAYDKLEKTKNRLQQELDDLLV-DLDHQRqlVSNLEKKQKKFDQMLAEEKA-ISARYAEERDRAEA 629

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1234 QVLEKEGESKELKRLVVAESEKSQKLEERLRLLQVET---------ASSSARAAERSS-ALREEVQSLR---EEVEKQRV 1300
Cdd:pfam01576  630 EAREKETRALSLARALEEALEAKEELERTNKQLRAEMedlvsskddVGKNVHELERSKrALEQQVEEMKtqlEELEDELQ 709

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1301 VSEN--LRQELASQAERAEESgQELKAWQEKFFQKEQALSA----LQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKR 1374
Cdd:pfam01576  710 ATEDakLRLEVNMQALKAQFE-RDLQARDEQGEEKRRQLVKqvreLEAELEDERKQRAQAVAAKKKLELDLKELEAQIDA 788

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1375 FREEIEQSKQAAGGLQAELMRAQRELGELGSLRQKIV----EQERAAQQLRAEKASYAEQLSMLKKAHGLLAEENRGLGE 1450
Cdd:pfam01576  789 ANKGREEAVKQLKKLQAQMKDLQRELEEARASRDEILaqskESEKKLKNLEAELLQLQEDLAASERARRQAQQERDELAD 868

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1451 RANLGRQFLEVELDQAREkyvqeLAAVRTDAETHLAEMRQEAQSTSRELEVMTAKYESAKVKVLEER---QRFQEERQKL 1527
Cdd:pfam01576  869 EIASGASGKSALQDEKRR-----LEARIAQLEEELEEEQSNTELLNDRLRKSTLQVEQLTTELAAERstsQKSESARQQL 943

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1528 TAQVEELNKKLTESEQASRVQQQ--------KLKAFQAQGGESQQE-------VQCLQTQLSELQAQLSQKEQAAEHYKL 1592
Cdd:pfam01576  944 ERQNKELKAKLQEMEGTVKSKFKssiaaleaKIAQLEEQLEQESRErqaanklVRRTEKKLKEVLLQVEDERRHADQYKD 1023

                         1050      1060      1070      1080      1090
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1958645968 1593 QMEKAKTHYDAKKQQNQELREQLQDLE----QLQKDNKELRSETERLGRELQQ 1641
Cdd:pfam01576 1024 QAEKGNSRMKQLKRQLEEAEEEASRANaarrKLQRELDDATESNESMNREVST 1076
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
504-900 1.16e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 47.07  E-value: 1.16e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  504 LNATLQQQDQELTSLKEQAKKEQAQMLQTLQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEAARQD-----HAQQ 578
Cdd:COG4717     47 LLERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREElekleKLLQ 126

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  579 LATIVEAREASVRERDAARQQLETLEKEKDAKLESLQQQLQASNEARDTAQTSVTQAQREKAELSQKIGELHACIEAAHQ 658
Cdd:COG4717    127 LLPLYQELEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQ 206

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  659 EQRQAQAHVTELEAQLKaEQQKATEREKVVQEKVQLQEQLQALEETLKIVRGSLEEEKCRAADALKEQQRHA-------- 730
Cdd:COG4717    207 RLAELEEELEEAQEELE-ELEEELEQLENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGvlflvlgl 285

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  731 --------TEMEAETRHLMEQREQEQKELEQEKAERKGLEARLQQLEEAHQAETEALRHELAGATAAQHGAESEREQLLR 802
Cdd:COG4717    286 lallflllAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQL 365

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  803 EV-----ESWQKRVEARQQEEARYGAMFQEQLMALKGEHGKIGQEEQKEAGEIHGEGQTGqqqsQLAQLHACLAKALQQV 877
Cdd:COG4717    366 EEleqeiAALLAEAGVEDEEELRAALEQAEEYQELKEELEELEEQLEELLGELEELLEAL----DEEELEEELEELEEEL 441

                          410       420
                   ....*....|....*....|...
gi 1958645968  878 QEKEARAQKLLDDLSALREKMAA 900
Cdd:COG4717    442 EELEEELEELREELAELEAELEQ 464
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 332-897 1.18e-04

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 47.27  E-value: 1.18e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  332 LQQLQGAFNDLIEEHSKAS--QEWAEKQAHLESELSTALQDKKCLEEKSEILQEKISQLEDRAAQ---LQGSPAPEKGEv 406
Cdd:TIGR00618  347 LQTLHSQEIHIRDAHEVATsiREISCQQHTLTQHIHTLQQQKTTLTQKLQSLCKELDILQREQATidtRTSAFRDLQGQ- 425

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  407 LGDALQLDTLKQEAAKLATDNTELQARVETLECERGKQEAQLLAERGHFEEEKRQLASLVADLQSSVSNLSQAKEELQQA 486
Cdd:TIGR00618  426 LAHAKKQQELQQRYAELCAAAITCTAQCEKLEKIHLQESAQSLKEREQQLQTKEQIHLQETRKKAVVLARLLELQEEPCP 505

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  487 SQAQGAQLTAQLASLTALNATlqqqdqelTSLKEQAKKEQAQMLQTLQEQEQAAQGLRQQVEQLSSSLKLKEQQLeeaak 566
Cdd:TIGR00618  506 LCGSCIHPNPARQDIDNPGPL--------TRRMQRGEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQSF----- 572

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  567 eqeaarQDHAQQLATIVEAREASVRERDAARQQLETLEKEKDAKLESLQQQLQASNEARDTAQTSVTQAQREKAELSQKI 646
Cdd:TIGR00618  573 ------SILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLACEQHALLRKLQPEQDLQDVRLHLQQCSQELALKLT 646

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  647 GELHACIEAAHQEQRQAQAHVTELEAQLKAEQQKATEREKvvQEKVQLQEQLQALEETLKIVRGSLEEEKcraadaLKEQ 726
Cdd:TIGR00618  647 ALHALQLTLTQERVREHALSIRVLPKELLASRQLALQKMQ--SEKEQLTYWKEMLAQCQTLLRELETHIE------EYDR 718

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  727 QRHATEMEAETRHLMEQREQEQKELEQEKAERKGLEArLQQLEEAHQAETEALRHELAGATaaqhgaesEREQLLREVES 806
Cdd:TIGR00618  719 EFNEIENASSSLGSDLAAREDALNQSLKELMHQARTV-LKARTEAHFNNNEEVTAALQTGA--------ELSHLAAEIQF 789

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  807 WQKRVEARQQE----EARYGAMFQEQLMALKGEHGKIGQEEQKEAGEIHGEGQT-GQQQSQLAQLHACLaKALQQVQEKE 881
Cdd:TIGR00618  790 FNRLREEDTHLlktlEAEIGQEIPSDEDILNLQCETLVQEEEQFLSRLEEKSATlGEITHQLLKYEECS-KQLAQLTQEQ 868

                          570
                   ....*....|....*.
gi 1958645968  882 ARAQKLLDDLSALREK 897
Cdd:TIGR00618  869 AKIIQLSDKLNGINQI 884
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
377-803 1.18e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 47.07  E-value: 1.18e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  377 KSEILQEKISQLEDRAAQLQGspapEKGEVLGDALQLDTLKQEAAKLATDNTELQARVETLEceRGKQEAQLLAERGHFE 456
Cdd:COG4717     65 KPELNLKELKELEEELKEAEE----KEEEYAELQEELEELEEELEELEAELEELREELEKLE--KLLQLLPLYQELEALE 138

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  457 EEKRQLASLVADLQSSVSNLSQAKEELQQASQAQGAQLTAQLASLTALNATLQQQDQELTSLKEQAKKEQAQMLQTLQEQ 536
Cdd:COG4717    139 AELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEA 218

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  537 EQAAQGLRQQVEQLSSSLKLKEQQ------------------LEEAAKEQEAARQDHAQQLATIVE--AREASVRERDAA 596
Cdd:COG4717    219 QEELEELEEELEQLENELEAAALEerlkearlllliaaallaLLGLGGSLLSLILTIAGVLFLVLGllALLFLLLAREKA 298

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  597 RQQLETLEKEKDAKLESLQQQLQAsnEARDTAQTSVTQAQREKAELSQKIGELHACIEAAHQEQRQAQAHVTELEAQLKA 676
Cdd:COG4717    299 SLGKEAEELQALPALEELEEEELE--ELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQEIAALL 376

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  677 EQQKATEREKVVQeKVQLQEQLQALEETLKIVRGSLEEEKCRAADALKEQQRhaTEMEAETRHLMEQREQEQKELEQEKA 756
Cdd:COG4717    377 AEAGVEDEEELRA-ALEQAEEYQELKEELEELEEQLEELLGELEELLEALDE--EELEEELEELEEELEELEEELEELRE 453

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|....*..
gi 1958645968  757 ERKGLEARLQQLEEAhqaetealrHELAGATAAQHGAESEREQLLRE 803
Cdd:COG4717    454 ELAELEAELEQLEED---------GELAELLQELEELKAELRELAEE 491
EmrA COG1566
Multidrug resistance efflux pump EmrA [Defense mechanisms];
543-675 1.29e-04

Multidrug resistance efflux pump EmrA [Defense mechanisms];


Pssm-ID: 441174 [Multi-domain]  Cd Length: 331  Bit Score: 46.58  E-value: 1.29e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  543 LRQQVEQLSSSLKLKEQQLEEAAKEQEAaRQDHAQQLATIVEAREasvrERDAARQQLETLEKEKDAKLESlQQQLQASN 622
Cdd:COG1566     81 LQAALAQAEAQLAAAEAQLARLEAELGA-EAEIAAAEAQLAAAQA----QLDLAQRELERYQALYKKGAVS-QQELDEAR 154

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1958645968  623 EARDTAQTSVTQAQREKAELSQKIGELhACIEAAHQEQRQAQAHVTELEAQLK 675
Cdd:COG1566    155 AALDAAQAQLEAAQAQLAQAQAGLREE-EELAAAQAQVAQAEAALAQAELNLA 206
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1490-1690 1.30e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 46.68  E-value: 1.30e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1490 QEAQSTSRELEVMTAKYESAKvkvlEERQRFQEERQKLTAQVEELNKKLTESEQASRVQQQKLKAFQAQGGESQQEVQCL 1569
Cdd:COG4942     20 DAAAEAEAELEQLQQEIAELE----KELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAEL 95

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1570 QTQLSELQAQLSQK--------------------------------EQAAEHYKLQMEKAKTHYDAKKQQNQELREQLQD 1617
Cdd:COG4942     96 RAELEAQKEELAELlralyrlgrqpplalllspedfldavrrlqylKYLAPARREQAEELRADLAELAALRAELEAERAE 175

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1958645968 1618 LEQL----QKDNKELRSETERLGRELQQAGLKTKEAEQACRHLTAQVRSLEAQVAHADQQLRDLGKFQVATDALKSR 1690
Cdd:COG4942    176 LEALlaelEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAGFAALK 252
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 306-649 1.43e-04

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 47.27  E-value: 1.43e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  306 QMDRKISQLSEENGDLSFKVREFANHLQQLQGAFNDLIEEHSKASQEWAEKQAHLESELSTALQDKKCLEEKSEilQEKI 385
Cdd:TIGR00618  532 RGEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSE--AEDM 609

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  386 SQLEDRAAQLQGSPAPEKGEVLGD--------ALQLDTLKQEAAKLATDN-TELQARVETLECERGKQEAQLLAERGHFE 456
Cdd:TIGR00618  610 LACEQHALLRKLQPEQDLQDVRLHlqqcsqelALKLTALHALQLTLTQERvREHALSIRVLPKELLASRQLALQKMQSEK 689

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  457 EEKRQLASLVADLQSSVSNLSQAKEELQQASQAQGAQLTAQLASLTALNATLQQQDQELTSLKEQAKKEQAQMLQTLQEQ 536
Cdd:TIGR00618  690 EQLTYWKEMLAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAAREDALNQSLKELMHQARTVLKARTEAHFNNNEE 769

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  537 EQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEAARQDHAQQLATIVEAREASVRERDAARQQLETLEKEKDAKLESLQQ 616
Cdd:TIGR00618  770 VTAALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQCETLVQEEEQFLSRLEEKSATLGEITH 849

                          330       340       350
                   ....*....|....*....|....*....|...
gi 1958645968  617 QLQASNEARDTAQtsvtQAQREKAELSQKIGEL 649
Cdd:TIGR00618  850 QLLKYEECSKQLA----QLTQEQAKIIQLSDKL 878
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
870-1296 1.52e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 46.68  E-value: 1.52e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  870 LAKALQQVQEKEARAQKLLDDLSALREKMAATNKEVACLKALVLKAGEQQAAASHELKEppRAGNQESDWEEEQARPLGS 949
Cdd:COG4717     76 LEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLYQEL--EALEAELAELPERLEELEE 153

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  950 TQAALKAVQREAEQMGGELERLRAALMQsqgQQQEVRGQQEREVARLTQERGQAQADLAQEKAAKAelemRLQNTLNEQR 1029
Cdd:COG4717    154 RLEELRELEEELEELEAELAELQEELEE---LLEQLSLATEEELQDLAEELEELQQRLAELEEELE----EAQEELEELE 226

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1030 VEFAALQEALTHAmtekegKDQELAKLREQEAAQISELKALQQTLEELKKKEKEHPTGGARGEDASGDGPGSQLHTPGKT 1109
Cdd:COG4717    227 EELEQLENELEAA------ALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLLLAREKASL 300

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1110 EAPGPEVEALrAEISKLERQWQQQQQQVEGLTHSLESERAcrAEQDKALETLQGQLEEKARElgHNQAASASAQRELQAL 1189
Cdd:COG4717    301 GKEAEELQAL-PALEELEEEELEELLAALGLPPDLSPEEL--LELLDRIEELQELLREAEEL--EEELQLEELEQEIAAL 375

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1190 RAKAQDHSKAE-EEWKAQVARGQQEAERKSSLISSLEEEVSILNRQVLEKEGES--KELKRLVVAESEKSQKLEE-RLRL 1265
Cdd:COG4717    376 LAEAGVEDEEElRAALEQAEEYQELKEELEELEEQLEELLGELEELLEALDEEEleEELEELEEELEELEEELEElREEL 455

                          410       420       430
                   ....*....|....*....|....*....|.
gi 1958645968 1266 LQVETASSSARAAERSSALREEVQSLREEVE 1296
Cdd:COG4717    456 AELEAELEQLEEDGELAELLQELEELKAELR 486
PRK11281 PRK11281
mechanosensitive channel MscK;
467-738 1.54e-04

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 47.21  E-value: 1.54e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  467 ADLQSSVSNLSQAKeelqqasqaqgaqltaqlaSLTALNATLQQ---QDQELTSLKEQAKKEQAQMLQTLQeqeQAAQGL 543
Cdd:PRK11281    39 ADVQAQLDALNKQK-------------------LLEAEDKLVQQdleQTLALLDKIDRQKEETEQLKQQLA---QAPAKL 96

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  544 RQQVEQLSsslKLKEQQleeaakeQEAARQDHAQQLATIVEAREASVRerdaarQQLETLEKEkdakLESLQQQLQASNE 623
Cdd:PRK11281    97 RQAQAELE---ALKDDN-------DEETRETLSTLSLRQLESRLAQTL------DQLQNAQND----LAEYNSQLVSLQT 156

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  624 ARDTAQTSVTQAQREKAELSQKIGELHACIEAAHQEQRQA-QAHVTELEAQLKAEQQKA----------TEREKVVQEKV 692
Cdd:PRK11281   157 QPERAQAALYANSQRLQQIRNLLKGGKVGGKALRPSQRVLlQAEQALLNAQNDLQRKSLegntqlqdllQKQRDYLTARI 236

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1958645968  693 Q-LQEQLQALEETLKIVRGSLEEEKCRAADALKEQQRH------ATEMEAETR 738
Cdd:PRK11281   237 QrLEHQLQLLQEAINSKRLTLSEKTVQEAQSQDEAARIqanplvAQELEINLQ 289
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 272-1072 1.75e-04

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 46.96  E-value: 1.75e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  272 EPSELEELRGKNESLTVRLHETLKQCQNLKTEKNQMDRKISQLSEENGDLSFKVREfanhlqqlqgAFNDLIEEHSKASQ 351
Cdd:TIGR00606  246 ELDPLKNRLKEIEHNLSKIMKLDNEIKALKSRKKQMEKDNSELELKMEKVFQGTDE----------QLNDLYHNHQRTVR 315

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  352 EWAEKQAHLESELSTALQDKKCLEEKSEILQEKISQLEDRAAQLQGSPAPEKGEVLGDALQ--LDTLKQEAAKLATDNTE 429
Cdd:TIGR00606  316 EKERELVDCQRELEKLNKERRLLNQEKTELLVEQGRLQLQADRHQEHIRARDSLIQSLATRleLDGFERGPFSERQIKNF 395

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  430 LQARVETLEcERGKQEAQLLAERGHFEEEKRQLASLVADLQSSVSNLSQAKEELQQASQAQGAQLTAQLASLTALNATLQ 509
Cdd:TIGR00606  396 HTLVIERQE-DEAKTAAQLCADLQSKERLKQEQADEIRDEKKGLGRTIELKKEILEKKQEELKFVIKELQQLEGSSDRIL 474

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  510 QQDQELT-SLKEQAKKEQAQMLQTLQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEAARQDHAQQLATIVEAREA 588
Cdd:TIGR00606  475 ELDQELRkAERELSKAEKNSLTETLKKEVKSLQNEKADLDRKLRKLDQEMEQLNHHTTTRTQMEMLTKDKMDKDEQIRKI 554

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  589 SVRERDAARQQ-------------LETLEKEKDA---KLESLQQQLQASNEARDTAQTSVTQAQREKAELSQKIGELHAC 652
Cdd:TIGR00606  555 KSRHSDELTSLlgyfpnkkqledwLHSKSKEINQtrdRLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKLFDVCGS 634

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  653 ------IEAAHQEQRQAQAHVTELEAQLKAEQQKATEREKVVQEKVQLQEQLQALEETLKIVRGSLEEEKCRAADALKEQ 726
Cdd:TIGR00606  635 qdeesdLERLKEEIEKSSKQRAMLAGATAVYSQFITQLTDENQSCCPVCQRVFQTEAELQEFISDLQSKLRLAPDKLKST 714

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  727 QRHATEMEAETRHLMEQREQEQKELEQEKAERKGLEARLQQLEEAHQAETEALRHE--LAGATAAQhgaESEREQLLREV 804
Cdd:TIGR00606  715 ESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQetLLGTIMPE---EESAKVCLTDV 791

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  805 ESWQKRVEARQQEEARYGAMFQE----QLMALKGEHGKIGQEEQKEAGEIHGEGQTGQQQSQLAQ-LHACLAKALQQVQE 879
Cdd:TIGR00606  792 TIMERFQMELKDVERKIAQQAAKlqgsDLDRTVQQVNQEKQEKQHELDTVVSKIELNRKLIQDQQeQIQHLKSKTNELKS 871

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  880 KEARAQKLLDDLSALREKMAATNKEVACLKALVLKAGEQQAAASHELKEPPRAGNQESDWEEEQARplgSTQAALKAVQR 959
Cdd:TIGR00606  872 EKLQIGTNLQRRQQFEEQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEELISSKETSNK---KAQDKVNDIKE 948

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  960 EAEQMGGELERLRAALMQSQGQQQEvrgQQEREVARLTqergqAQADLAQEKAAKAELEMRL-QNTLNEQRVEFAALQEA 1038
Cdd:TIGR00606  949 KVKNIHGYMKDIENKIQDGKDDYLK---QKETELNTVN-----AQLEECEKHQEKINEDMRLmRQDIDTQKIQERWLQDN 1020

                          810       820       830
                   ....*....|....*....|....*....|....
gi 1958645968 1039 LTHAMTEKEGKdqELAKLREQEAAQISELKALQQ 1072
Cdd:TIGR00606 1021 LTLRKRENELK--EVEEELKQHLKEMGQMQVLQM 1052
EmrA COG1566
Multidrug resistance efflux pump EmrA [Defense mechanisms];
1555-1677 1.88e-04

Multidrug resistance efflux pump EmrA [Defense mechanisms];


Pssm-ID: 441174 [Multi-domain]  Cd Length: 331  Bit Score: 45.81  E-value: 1.88e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1555 FQAQGGESQQEVQCLQTQLSELQAQLSQKEQAAEhYKLQMEKAKTHYDAKKQQ---NQELREQ----LQDLEQLQKDNKE 1627
Cdd:COG1566     81 LQAALAQAEAQLAAAEAQLARLEAELGAEAEIAA-AEAQLAAAQAQLDLAQRElerYQALYKKgavsQQELDEARAALDA 159

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1628 LRSETERLGRELQQAGLKTKEAEQAcRHLTAQVRSLEAQVAHADQQLRDL 1677
Cdd:COG1566    160 AQAQLEAAQAQLAQAQAGLREEEEL-AAAQAQVAQAEAALAQAELNLART 208
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 967-1651 2.04e-04

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 46.50  E-value: 2.04e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  967 ELERLRAALMQSQGQQQEVRGQQEREVARLTQERGQAQADLAQEKAAKAELEMRLQNTLNEQRVEFAALQEALTHAMTEK 1046
Cdd:TIGR00618  227 ELKHLREALQQTQQSHAYLTQKREAQEEQLKKQQLLKQLRARIEELRAQEAVLEETQERINRARKAAPLAAHIKAVTQIE 306

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1047 EGKDQELAKLREQEAAQISELKALQQTLEElkkkekehptggaRGEDASGDGPGSQLHTPGKTEAPGPEVEALRAEISKL 1126
Cdd:TIGR00618  307 QQAQRIHTELQSKMRSRAKLLMKRAAHVKQ-------------QSSIEEQRRLLQTLHSQEIHIRDAHEVATSIREISCQ 373

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1127 ERQwqqqqqqvegLTHSLESERAcRAEQDKALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQDHSKAEEEWKAQ 1206
Cdd:TIGR00618  374 QHT----------LTQHIHTLQQ-QKTTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAEL 442

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1207 VargQQEAERKSSLISSLEEEVSILNRQVLEKEGESKELKRLVVAESEKSQKLEERLRLLQVETA---------SSSARA 1277
Cdd:TIGR00618  443 C---AAAITCTAQCEKLEKIHLQESAQSLKEREQQLQTKEQIHLQETRKKAVVLARLLELQEEPCplcgscihpNPARQD 519

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1278 AERSSALREEVQSLREEVEKQRVVSENLRQELASQAERAEESGQELKAWQEKFFQKEQALSALQLEHTSTQALVSELLPa 1357
Cdd:TIGR00618  520 IDNPGPLTRRMQRGEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQD- 598

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1358 khlcqqlqaeqaaaekRFREEIEQSKQAAGGLQAELMRAQRELGELgSLRQKIVEQERAAQQLRAEKASYAEQLSMLKKA 1437
Cdd:TIGR00618  599 ----------------LTEKLSEAEDMLACEQHALLRKLQPEQDLQ-DVRLHLQQCSQELALKLTALHALQLTLTQERVR 661

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1438 HGLLAeeNRGLGERANLGRQFLEVELdQAREKYVQELAAVRTDAETHLAEMRQEAQSTSRELEVMTAKYESAKVKVLEER 1517
Cdd:TIGR00618  662 EHALS--IRVLPKELLASRQLALQKM-QSEKEQLTYWKEMLAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAARE 738

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1518 QRFQEERQKLTAQVEELNKKLTESEQASRVQQQKLKAFQAQGGESQQEVQCLQTQLSELQAQLSQKEQAAEHYKLQMEKA 1597
Cdd:TIGR00618  739 DALNQSLKELMHQARTVLKARTEAHFNNNEEVTAALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDI 818

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1958645968 1598 KTHYDAKKQQnqELREQLQDLEQLQKDNKELRSETERLGRELQQAGLKTKEAEQ 1651
Cdd:TIGR00618  819 LNLQCETLVQ--EEEQFLSRLEEKSATLGEITHQLLKYEECSKQLAQLTQEQAK 870
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
412-820 2.12e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 46.30  E-value: 2.12e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  412 QLDTLKQEAAKLATDNTELQARVETLEcERGKQEAQLLAERGHFEEEKRQLASLVAdLQSSVSNLSQAKEELQQasqaqg 491
Cdd:COG4717     72 ELKELEEELKEAEEKEEEYAELQEELE-ELEEELEELEAELEELREELEKLEKLLQ-LLPLYQELEALEAELAE------ 143

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  492 aqLTAQLASLTALNATLQQQDQELTSLKEQAKKEQAQMLQTLQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEAA 571
Cdd:COG4717    144 --LPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEE 221

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  572 RQDHAQQLATIVEAREASVRERDAARQQLETLEKEKDAKLESLQQQLQASNEARDTAQTSVTQA--------QREKAELS 643
Cdd:COG4717    222 LEELEEELEQLENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLlallflllAREKASLG 301

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  644 QKIGELHACIEAAHQEQRQAQAHVTELEAQLKAEQQKATEREKVVQEKVQLQEQLQALEETLKIVR------GSLEEEKC 717
Cdd:COG4717    302 KEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEEleqeiaALLAEAGV 381

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  718 RAADALKE-----QQRHATEMEAETRHLMEQREQEQKELEQEKAERKGLEARLQQLEEAHQA---ETEALRHELAGATAA 789
Cdd:COG4717    382 EDEEELRAaleqaEEYQELKEELEELEEQLEELLGELEELLEALDEEELEEELEELEEELEEleeELEELREELAELEAE 461

                          410       420       430
                   ....*....|....*....|....*....|.
gi 1958645968  790 QHGAESEREqlLREVESWQKRVEARQQEEAR 820
Cdd:COG4717    462 LEQLEEDGE--LAELLQELEELKAELRELAE 490
mukB PRK04863
chromosome partition protein MukB;
406-732 2.14e-04

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 46.49  E-value: 2.14e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  406 VLGDAL---QLDTLKQEAAKLATDNTELQARVEtlECERGKQ------------------EAQLLAERGHFEEEKRQLAS 464
Cdd:PRK04863   778 LFGRAArekRIEQLRAEREELAERYATLSFDVQ--KLQRLHQafsrfigshlavafeadpEAELRQLNRRRVELERALAD 855

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  465 LVADLQSSVSNLSQAKEELQQASQAQGAQLTAQLASLTALNATLQQQDQELtslkEQAKKEQAQMLQTLQEQEQAAQGLR 544
Cdd:PRK04863   856 HESQEQQQRSQLEQAKEGLSALNRLLPRLNLLADETLADRVEEIREQLDEA----EEAKRFVQQHGNALAQLEPIVSVLQ 931

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  545 QQVEQLssslklkeQQLEEAAKEQEAARQDHAQQLATIVEAREasVRERDAARQQLETLEKEKDAKlESLQQQLQASNEA 624
Cdd:PRK04863   932 SDPEQF--------EQLKQDYQQAQQTQRDAKQQAFALTEVVQ--RRAHFSYEDAAEMLAKNSDLN-EKLRQRLEQAEQE 1000

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  625 RDTAQTSVTQAQREKAELSQKIGELHACIEAAHQEQRQAQAHVTEL--EAQLKAEQQKATEREKVVQEKVQLQEQLQALE 702
Cdd:PRK04863  1001 RTRAREQLRQAQAQLAQYNQVLASLKSSYDAKRQMLQELKQELQDLgvPADSGAEERARARRDELHARLSANRSRRNQLE 1080

                          330       340       350
                   ....*....|....*....|....*....|..
gi 1958645968  703 ETLKIVRGSLEE--EKCRAADALKEQQRHATE 732
Cdd:PRK04863  1081 KQLTFCEAEMDNltKKLRKLERDYHEMREQVV 1112
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
604-1140 2.16e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 46.45  E-value: 2.16e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  604 EKEKDAKLESLQQQLQASNEARDTAQTsvtqaQREKAELSQKIGELHACIEAAHQEQRQAQAHVTELEAQlkaeqQKATE 683
Cdd:COG4913    220 EPDTFEAADALVEHFDDLERAHEALED-----AREQIELLEPIRELAERYAAARERLAELEYLRAALRLW-----FAQRR 289

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  684 REKVVQEKVQLQEQLQALEETLKIVRGSLEEEKcRAADALKEQQRHA-----TEMEAETRHLmeqreqeQKELEQEKAER 758
Cdd:COG4913    290 LELLEAELEELRAELARLEAELERLEARLDALR-EELDELEAQIRGNggdrlEQLEREIERL-------ERELEERERRR 361

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  759 KGLEARLQQLEEAHQAETEALRHELAGATAAQHGAESEREQLLREV-ESWQKRVEARQQEEARygamfQEQLMALKGEHG 837
Cdd:COG4913    362 ARLEALLAALGLPLPASAEEFAALRAEAAALLEALEEELEALEEALaEAEAALRDLRRELREL-----EAEIASLERRKS 436

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  838 KIGQEEQKEAGEIhgEGQTGQQQS---------QLAQLHACLAKALQQV-----------QEKEARAQKLLDD------L 891
Cdd:COG4913    437 NIPARLLALRDAL--AEALGLDEAelpfvgeliEVRPEEERWRGAIERVlggfaltllvpPEHYAAALRWVNRlhlrgrL 514

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  892 SALREKMAATNKEVACLKA------LVLKAGEQQAAASHELKEP---------------PRA-----------GNQESDW 939
Cdd:COG4913    515 VYERVRTGLPDPERPRLDPdslagkLDFKPHPFRAWLEAELGRRfdyvcvdspeelrrhPRAitragqvkgngTRHEKDD 594

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  940 EEEQARP--LG-STQAALKAVQREAEQMGGELERLRAALMQSQGQQQEVRGQqeREVARLTQERGQAQADLAQEKAAKAE 1016
Cdd:COG4913    595 RRRIRSRyvLGfDNRAKLAALEAELAELEEELAEAEERLEALEAELDALQER--REALQRLAEYSWDEIDVASAEREIAE 672

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1017 LEMRLQNtLNEQRVEFAALQEALTHAMTEKEGKDQELAKLREQEAAQISELKALQQTLEELKKKEKEHPTGGARGEDASG 1096
Cdd:COG4913    673 LEAELER-LDASSDDLAALEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALL 751

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....
gi 1958645968 1097 DGpgsQLHTPGKTEAPGPEVEALRAEISKLERQWQQQQQQVEGL 1140
Cdd:COG4913    752 EE---RFAAALGDAVERELRENLEERIDALRARLNRAEEELERA 792
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 441-816 2.20e-04

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 46.48  E-value: 2.20e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  441 RGKQEAQLLAERGHFEEeKRQLASLvadlQSSVSNLSQAKEELQQASQAQGAQLTAQLASLTALNATLQQQD------QE 514
Cdd:COG3096    281 RELSERALELRRELFGA-RRQLAEE----QYRLVEMARELEELSARESDLEQDYQAASDHLNLVQTALRQQEkieryqED 355

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  515 LTSLKEQAKkEQAQMLQTLQEQEQAAQGLRQQVEQLSSSLK---------LKEQQLEEAAKEQEAARQDHAQQLATIVEA 585
Cdd:COG3096    356 LEELTERLE-EQEEVVEEAAEQLAEAEARLEAAEEEVDSLKsqladyqqaLDVQQTRAIQYQQAVQALEKARALCGLPDL 434

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  586 REASVRERDAArqqLETLEKEKDAKLESLQQQLQASNEARdtaqtsvtqAQREKA-ELSQKI-GELHAciEAAHQEQRQA 663
Cdd:COG3096    435 TPENAEDYLAA---FRAKEQQATEEVLELEQKLSVADAAR---------RQFEKAyELVCKIaGEVER--SQAWQTAREL 500

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  664 ------QAHVTELEAQLKAEQQKATEREKVVQEKVQLQEQLQ-------ALEETLKIVRGSLEEEKcraaDALKEQQRHA 730
Cdd:COG3096    501 lrryrsQQALAQRLQQLRAQLAELEQRLRQQQNAERLLEEFCqrigqqlDAAEELEELLAELEAQL----EELEEQAAEA 576

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  731 TEMEAETRHLMEQREQEQKELEQEKAERKGLEARLQQLEE---AHQAETEALRHELAGATAAQHGAESEREQLLREVESW 807
Cdd:COG3096    577 VEQRSELRQQLEQLRARIKELAARAPAWLAAQDALERLREqsgEALADSQEVTAAMQQLLEREREATVERDELAARKQAL 656


                   ....*....
gi 1958645968  808 QKRVEARQQ 816
Cdd:COG3096    657 ESQIERLSQ 665
MAD pfam05557
Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint ...
 1209-1638 2.30e-04

Mitotic checkpoint protein; This family consists of several eukaryotic mitotic checkpoint (Mitotic arrest deficient or MAD) proteins. The mitotic spindle checkpoint monitors proper attachment of the bipolar spindle to the kinetochores of aligned sister chromatids and causes a cell cycle arrest in prometaphase when failures occur. Multiple components of the mitotic spindle checkpoint have been identified in yeast and higher eukaryotes. In S.cerevisiae, the existence of a Mad1-dependent complex containing Mad2, Mad3, Bub3 and Cdc20 has been demonstrated.


Pssm-ID: 461677 [Multi-domain]  Cd Length: 660  Bit Score: 46.27  E-value: 2.30e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1209 RGQQEAERKSS-LISSLEEEVSilnrQVLEKEGESKELKRLVVAESEKSQKLEERLRLLQVETASSSARAAERSSAL--- 1284
Cdd:pfam05557   27 RARIELEKKASaLKRQLDRESD----RNQELQKRIRLLEKREAEAEEALREQAELNRLKKKYLEALNKKLNEKESQLada 102

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1285 REEVQSLREEVEKQRVVSENLRQELASQAERAEESGQELKAWQEKFFQKEQALSALQlehTSTQALVSELLPAKHLcqql 1364
Cdd:pfam05557  103 REVISCLKNELSELRRQIQRAELELQSTNSELEELQERLDLLKAKASEAEQLRQNLE---KQQSSLAEAEQRIKEL---- 175

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1365 qaeqaaaeKRFREEIEQSKQAAGGLQAELMRaqrelgelgslrqkIVEQERAAQQLRAEKasyaEQLSMLKKAHGLLAEE 1444
Cdd:pfam05557  176 --------EFEIQSQEQDSEIVKNSKSELAR--------------IPELEKELERLREHN----KHLNENIENKLLLKEE 229

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1445 NRGLgeRANLGRQ--------FLEVELdqarEKYVQELAAVRTDAETHLAEMR-------QEAQSTSRELEVMTAKYESA 1509
Cdd:pfam05557  230 VEDL--KRKLEREekyreeaaTLELEK----EKLEQELQSWVKLAQDTGLNLRspedlsrRIEQLQQREIVLKEENSSLT 303

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1510 KVKVLEERQR--FQEERQKLTAQVEELNKKLTE-SEQASRVQQQKLKAFQAQGG-------------------------- 1560
Cdd:pfam05557  304 SSARQLEKARreLEQELAQYLKKIEDLNKKLKRhKALVRRLQRRVLLLTKERDGyrailesydkeltmsnyspqllerie 383

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1561 ESQQEVQCLQTQLSELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQ--ELREQLQDLEQLQKDNKELRSETERLGRE 1638
Cdd:pfam05557  384 EAEDMTQKMQAHNEEMEAQLSVAEEELGGYKQQAQTLERELQALRQQESlaDPSYSKEEVDSLRRKLETLELERQRLREQ 463
PRK10920 PRK10920
putative uroporphyrinogen III C-methyltransferase; Provisional
 497-561 2.39e-04

putative uroporphyrinogen III C-methyltransferase; Provisional


Pssm-ID: 236795  Cd Length: 390  Bit Score: 45.86  E-value: 2.39e-04
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1958645968  497 QLASLTALNATLQQQdqeLTSLKEQAKKEQAQMLQTLQEQEQAAQGLRQQVEQLSSSLKLKEQQL 561
Cdd:PRK10920    61 QAQNQTATNDALANQ---LTALQKAQESQKQELEGILKQQAKALDQANRQQAALAKQLDELQQKV 122
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1279-1679 2.42e-04

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 46.19  E-value: 2.42e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1279 ERSSALREEVQSLREEVEkqrvvsenlrqELASQAERAEESGQELKAWQEKFFQKEQALSALQLEHTSTQALVSEllpak 1358
Cdd:PRK02224   206 ERLNGLESELAELDEEIE-----------RYEEQREQARETRDEADEVLEEHEERREELETLEAEIEDLRETIAE----- 269

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1359 hlcqqlqaeQAAAEKRFREEIEQSKQAAGGLQAELMRAQRELGeLGSLRQKIVEQERAAqqLRAEKASYAEQLSMLKKAH 1438
Cdd:PRK02224   270 ---------TEREREELAEEVRDLRERLEELEEERDDLLAEAG-LDDADAEAVEARREE--LEDRDEELRDRLEECRVAA 337

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1439 GLLAEENRGLGERANLgrqfLEVELDQAREKyVQELAAVRTDAETHLAEMRQEAQSTSRELEVMTAKYESAKV---KVLE 1515
Cdd:PRK02224   338 QAHNEEAESLREDADD----LEERAEELREE-AAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVdlgNAED 412

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1516 ERQRFQEERQKLTAQVEELNKKLTESEQASRVQQQKLKAFQ----AQGGESQQEVQCL---QTQLSELQAQLSQKEQAAE 1588
Cdd:PRK02224   413 FLEELREERDELREREAELEATLRTARERVEEAEALLEAGKcpecGQPVEGSPHVETIeedRERVEELEAELEDLEEEVE 492

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1589 HYKLQMEKAKTHYDAKKQQnQELREQLQDLEQLQKDNKE-----------LRSETERLGRELQQAGLKTKEAEQACRHLT 1657
Cdd:PRK02224   493 EVEERLERAEDLVEAEDRI-ERLEERREDLEELIAERREtieekreraeeLRERAAELEAEAEEKREAAAEAEEEAEEAR 571

                          410       420
                   ....*....|....*....|..
gi 1958645968 1658 AQVRSLEAQVAHADQQLRDLGK 1679
Cdd:PRK02224   572 EEVAELNSKLAELKERIESLER 593
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
1532-1637 2.65e-04

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 46.00  E-value: 2.65e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1532 EELNKKLTESEQASRVQQQKLKAFQAQGGESQQEVQCLQTQLSELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQEL 1611
Cdd:COG2433    388 KELPEEEPEAEREKEHEERELTEEEEEIRRLEEQVERLEAEVEELEAELEEKDERIERLERELSEARSEERREIRKDREI 467

                           90       100       110
                   ....*....|....*....|....*....|...
gi 1958645968 1612 R------EQLQ-DLEQLQKDNKELRSETERLGR 1637
Cdd:COG2433    468 SrldreiERLErELEEERERIEELKRKLERLKE 500
PRK00409 PRK00409
recombination and DNA strand exchange inhibitor protein; Reviewed
 1556-1665 3.05e-04

recombination and DNA strand exchange inhibitor protein; Reviewed


Pssm-ID: 234750 [Multi-domain]  Cd Length: 782  Bit Score: 45.97  E-value: 3.05e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1556 QAQGGESQQEVQCLQTQLSELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQELREQL-QDLEQ-LQKDNKELRSETE 1633
Cdd:PRK00409   508 KKLIGEDKEKLNELIASLEELERELEQKAEEAEALLKEAEKLKEELEEKKEKLQEEEDKLlEEAEKeAQQAIKEAKKEAD 587

                           90       100       110
                   ....*....|....*....|....*....|....*...
gi 1958645968 1634 RLGREL------QQAGLKTKEAEQACRHLTAQVRSLEA 1665
Cdd:PRK00409   588 EIIKELrqlqkgGYASVKAHELIEARKRLNKANEKKEK 625
PRK11637 PRK11637
AmiB activator; Provisional
 597-826 3.43e-04

AmiB activator; Provisional


Pssm-ID: 236942 [Multi-domain]  Cd Length: 428  Bit Score: 45.45  E-value: 3.43e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  597 RQQLETLEKEKDAKLESLQQ----------QLQASNEARDTAQTSVTQAQREKAELSQKIGELHACIEAAHQEQRQAQah 666
Cdd:PRK11637    46 RDQLKSIQQDIAAKEKSVRQqqqqrasllaQLKKQEEAISQASRKLRETQNTLNQLNKQIDELNASIAKLEQQQAAQE-- 123

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  667 vTELEAQLKA--EQQKATEREKVVQ-EKVQLQEQLQALEETLKIVRGSLEEEKCRAADALKEQQRHATEMEAETRHLMEQ 743
Cdd:PRK11637   124 -RLLAAQLDAafRQGEHTGLQLILSgEESQRGERILAYFGYLNQARQETIAELKQTREELAAQKAELEEKQSQQKTLLYE 202

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  744 REQEQKELEQEKAERK----GLEARL----QQLEEAHQAETEaLRHELAGATAAQHgAESEREQllREVEswqkRVEARQ 815
Cdd:PRK11637   203 QQAQQQKLEQARNERKktltGLESSLqkdqQQLSELRANESR-LRDSIARAEREAK-ARAEREA--REAA----RVRDKQ 274

                          250
                   ....*....|.
gi 1958645968  816 QEEARYGAMFQ 826
Cdd:PRK11637   275 KQAKRKGSTYK 285
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 294-914 3.48e-04

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 45.81  E-value: 3.48e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  294 LKQCQNLKTEKNQMDRKISQLSEENGDLsfkvrefaNHLQQLQGAFNDLIEEHSKASQEWAEKQAHLESELSTALQD--- 370
Cdd:TIGR00606  500 KKEVKSLQNEKADLDRKLRKLDQEMEQL--------NHHTTTRTQMEMLTKDKMDKDEQIRKIKSRHSDELTSLLGYfpn 571

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  371 KKCLEEKSEILQEKISQLEDRAAQLQGSPApeKGEVLGDALQLDTLKQEAAKLATDNTELQArvetleCERGKQEAQLLA 450
Cdd:TIGR00606  572 KKQLEDWLHSKSKEINQTRDRLAKLNKELA--SLEQNKNHINNELESKEEQLSSYEDKLFDV------CGSQDEESDLER 643

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  451 ERGHFEEEKRQLASLVADLQSSVSNLSQAKEE------LQQASQAQGAQLTAQLASLTALNATLQQQDQELTSLKEQAKK 524
Cdd:TIGR00606  644 LKEEIEKSSKQRAMLAGATAVYSQFITQLTDEnqsccpVCQRVFQTEAELQEFISDLQSKLRLAPDKLKSTESELKKKEK 723

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  525 EQAQMLQTLQEQeqaaQGLRQQVEQLSSSLKLKEQQLEEAAKEQEAARQDHAQQLATIV-EAREASVRERDAA-RQQLET 602
Cdd:TIGR00606  724 RRDEMLGLAPGR----QSIIDLKEKEIPELRNKLQKVNRDIQRLKNDIEEQETLLGTIMpEEESAKVCLTDVTiMERFQM 799

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  603 LEKEKDAKLESLQQQLQASNEARDTAQTS--VTQAQREKAELSQKIGELHACIEAAHQEQRQAQAHVTELEAQLKAEQQK 680
Cdd:TIGR00606  800 ELKDVERKIAQQAAKLQGSDLDRTVQQVNqeKQEKQHELDTVVSKIELNRKLIQDQQEQIQHLKSKTNELKSEKLQIGTN 879

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  681 ATEREKVVQEKVQLQEQLQALEETLKIVRGSLEEEKCRAADALKEQQRHATEMEAETRHLMEQREQEQKELEQEKAERKG 760
Cdd:TIGR00606  880 LQRRQQFEEQLVELSTEVQSLIREIKDAKEQDSPLETFLEKDQQEKEELISSKETSNKKAQDKVNDIKEKVKNIHGYMKD 959

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  761 LEARLQQLEEAHQAETEalrHELAGATAAQHGAESEREQLLREVESWQKRVEARQQEEA--------------------- 819
Cdd:TIGR00606  960 IENKIQDGKDDYLKQKE---TELNTVNAQLEECEKHQEKINEDMRLMRQDIDTQKIQERwlqdnltlrkrenelkeveee 1036

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  820 ---RYGAMFQEQLMALKGEHGKIgQEEQKEAGEIHGEGQTGQQQSQLAQLHACLAKALQQVQEKEARAQKLLDDLSALRE 896
Cdd:TIGR00606 1037 lkqHLKEMGQMQVLQMKQEHQKL-EENIDLIKRNHVLALGRQKGYEKEIKHFKKELREPQFRDAEEKYREMMIVMRTTEL 1115

                          650
                   ....*....|....*...
gi 1958645968  897 KMAATNKEVACLKALVLK 914
Cdd:TIGR00606 1116 VNKDLDIYYKTLDQAIMK 1133
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1241-1648 3.57e-04

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 45.83  E-value: 3.57e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1241 ESKELKRLVVAESEksqkLEERLRLLQVETASSSARAAERSS---ALREEVQSLREEVEKQrvvsENLRQELASQAERAE 1317
Cdd:PRK03918   177 RIERLEKFIKRTEN----IEELIKEKEKELEEVLREINEISSelpELREELEKLEKEVKEL----EELKEEIEELEKELE 248

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1318 ESGQELKAWQEKFFQKEQALSALQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKrFREEIEQSKQAAGGLQAELMRAQ 1397
Cdd:PRK03918   249 SLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKEKAEEYIKLSEFYEE-YLDELREIEKRLSRLEEEINGIE 327

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1398 RELGELGSLRQKIVEQERAAQQLRAEKASYAEQLSMLKKAHGLLAEENRGLGERANLGRQFLEVELDQArEKYVQELaav 1477
Cdd:PRK03918   328 ERIKELEEKEERLEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLTPEKLEKELEEL-EKAKEEI--- 403

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1478 rTDAETHLAEMRQEAQSTSRELEVMTAKYESAKVKVL--------EERQRFQEERQKLTAQVEELNKKLTESEQASRVQQ 1549
Cdd:PRK03918   404 -EEEISKITARIGELKKEIKELKKAIEELKKAKGKCPvcgrelteEHRKELLEEYTAELKRIEKELKEIEEKERKLRKEL 482

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1550 QKLKAFQAQGGESQQEVQCLQtQLSELQAQLSqkeqaaEHYKLQMEKAKTHYDAKKQQNQELREQLQDLEQLQKDNKELR 1629
Cdd:PRK03918   483 RELEKVLKKESELIKLKELAE-QLKELEEKLK------KYNLEELEKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEELK 555

                          410
                   ....*....|....*....
gi 1958645968 1630 SETERLGRELQQAGLKTKE 1648
Cdd:PRK03918   556 KKLAELEKKLDELEEELAE 574
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1151-1355 3.81e-04

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 45.78  E-value: 3.81e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1151 RAEQDKALETLQGQLEEKARELghnqaasASAQRELQALRAKAQdhskaeeewkaqVARGQQEAERKSSLISSLEEEVSI 1230
Cdd:COG3206    170 REEARKALEFLEEQLPELRKEL-------EEAEAALEEFRQKNG------------LVDLSEEAKLLLQQLSELESQLAE 230

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1231 LNRQVLEKEGESKELKRLV---------VAESEKSQKLEERLRLLQVETASSSARAAERSS---ALREEVQSLR----EE 1294
Cdd:COG3206    231 ARAELAEAEARLAALRAQLgsgpdalpeLLQSPVIQQLRAQLAELEAELAELSARYTPNHPdviALRAQIAALRaqlqQE 310

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1958645968 1295 VEKQRVVSENLRQELASQAERAEESGQELKAWQEKFFQKEQALSALQLEHTSTQALVSELL 1355
Cdd:COG3206    311 AQRILASLEAELEALQAREASLQAQLAQLEARLAELPELEAELRRLEREVEVARELYESLL 371
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 480-693 3.85e-04

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 45.21  E-value: 3.85e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  480 KEELQQASQAQGAQLTAQLASLTALNATLQQQDQELTSLKEQAKKEQAQMLQTLQEQEQAAQGLRQQVEQLSSSLKLKEQ 559
Cdd:COG3883     18 IQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARALYR 97

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  560 QLEEAAKEQEAARQ-------DHAQQLATIVEAREASVRERDAARQQLETLEKEKDAKLESLQQQLQASNEARDTAQTSV 632
Cdd:COG3883     98 SGGSVSYLDVLLGSesfsdflDRLSALSKIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAELEAQQ 177

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1958645968  633 TQAQREKAELSQKIGELHACIEAAHQEQRQAQAHVTELEAQLKAEQQKATEREKVVQEKVQ 693
Cdd:COG3883    178 AEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAAAA 238
HpsJ_fam NF038305
HpsJ family protein; HpsJ (hormogornium polysaccharide J) is thought to be involved in the ...
 504-619 4.30e-04

HpsJ family protein; HpsJ (hormogornium polysaccharide J) is thought to be involved in the biosynthesis or secretion of an extracellular polysaccharide shared by many Cyanobacteria.


Pssm-ID: 468465 [Multi-domain]  Cd Length: 230  Bit Score: 44.11  E-value: 4.30e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  504 LNATLQQQDQELTSLKEQAKKEQAQmLQTLQEQEQAAQGlRQQVEQLSSSLKLKEQQLEEAAKEqeaarQDHAQQLATIV 583
Cdd:NF038305    99 LNNTRRLSTQALQQINQQAGQQETQ-LQQQLNQLQAQTS-PQQLNQLLKSEQKQGQALASGQLP-----EEQKEQLQQFK 171

                           90       100       110
                   ....*....|....*....|....*....|....*...
gi 1958645968  584 EAREASVRERDAARQQLET--LEKEKDAKLESLQQQLQ 619
Cdd:NF038305   172 SNPQALDKFLAQQLTQIRTqaEEAEKQARLEALKSSLR 209
46 PHA02562
endonuclease subunit; Provisional
 1468-1688 4.48e-04

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 45.39  E-value: 4.48e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1468 EKYVQELAAVRTDAETHLAEMRQEAQSTSRELEvmtAKYESAKVKVLEerqrFQEERQKLTAQVEELNKKLTESeqASRV 1547
Cdd:PHA02562   201 NKNIEEQRKKNGENIARKQNKYDELVEEAKTIK---AEIEELTDELLN----LVMDIEDPSAALNKLNTAAAKI--KSKI 271

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1548 QQ-QKLKAFQAQGGESQQevqCLQtQLSELQAQLSQKEQAAEHYKLQMEKAKTHYDakkqqnqELREQLQDLEQLQKDNK 1626
Cdd:PHA02562   272 EQfQKVIKMYEKGGVCPT---CTQ-QISEGPDRITKIKDKLKELQHSLEKLDTAID-------ELEEIMDEFNEQSKKLL 340

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1958645968 1627 ELRSETERLGRELQQAGLKTKEAEQACRHLTAQVRSLEAQVAHADQQLRDLGK-----------FQVATDALK 1688
Cdd:PHA02562   341 ELKNKISTNKQSLITLVDKAKKVKAAIEELQAEFVDNAEELAKLQDELDKIVKtkselvkekyhRGIVTDLLK 413
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
253-665 4.72e-04

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 45.14  E-value: 4.72e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  253 QQRIDHLALLNEKQAASPQEPSELEELRGKNESLtVRLHETLKQCQNLKTEKNQMDRKISQLSEENGDLSFKVREFANHL 332
Cdd:COG4717     91 AELQEELEELEEELEELEAELEELREELEKLEKL-LQLLPLYQELEALEAELAELPERLEELEERLEELRELEEELEELE 169

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  333 QQLQGAFNDLIEEHSKASQEWAEKQAHLESELSTALQDKKCLEEKSEILQEKISQLEDRAAQLQgspapEKGEVLGDALQ 412
Cdd:COG4717    170 AELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLE-----NELEAAALEER 244

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  413 LDTLKQEAAKLATdntelqarvetlecergkqEAQLLAERGHFEEEKRQLASLVADLQSSVSNLSQakeeLQQASQAQGA 492
Cdd:COG4717    245 LKEARLLLLIAAA-------------------LLALLGLGGSLLSLILTIAGVLFLVLGLLALLFL----LLAREKASLG 301

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  493 QLTAQLASLTALNATLQQQDQELTSLKEQAKKEQAQMLQTLQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEAAR 572
Cdd:COG4717    302 KEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQEIAALLAEAGV 381

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  573 QDHAQ--QLATIVEAREASVRERDAARQQLETLEKE-----KDAKLESLQQQLQASNEARDTAQTSVTQAQREKAELSQK 645
Cdd:COG4717    382 EDEEElrAALEQAEEYQELKEELEELEEQLEELLGEleellEALDEEELEEELEELEEELEELEEELEELREELAELEAE 461

                          410       420
                   ....*....|....*....|
gi 1958645968  646 IGELHACIEAAHQEQRQAQA 665
Cdd:COG4717    462 LEQLEEDGELAELLQELEEL 481
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 967-1309 5.58e-04

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 45.11  E-value: 5.58e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  967 ELERLRAALMQSQGQQQEVRGQQEREVARLTQERgqaqadLAQEKAAKA-ELEMRLQNTLNEQRVEFAALQEALTHAMTE 1045
Cdd:pfam17380  267 ENEFLNQLLHIVQHQKAVSERQQQEKFEKMEQER------LRQEKEEKArEVERRRKLEEAEKARQAEMDRQAAIYAEQE 340

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1046 K--------------EGKDQELAKLREQE-AAQISELKALQQTleelkkkekehptggargedasgdgpgsQLHTPGKTE 1110
Cdd:pfam17380  341 RmamererelerirqEERKRELERIRQEEiAMEISRMRELERL----------------------------QMERQQKNE 392

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1111 APGPEVEALRA-EISKLERQWQQQQQQVEGLTHSLESERAcRAEQDKALEtlqgqlEEKARELGHNQAASASAQRELQAL 1189
Cdd:pfam17380  393 RVRQELEAARKvKILEEERQRKIQQQKVEMEQIRAEQEEA-RQREVRRLE------EERAREMERVRLEEQERQQQVERL 465

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1190 RAKAQDHSKAEEEW-KAQVARGQQEAERKSSLISSLEEEVSIL-----NRQVLEKEGESK-------ELKRLVVAESEKS 1256
Cdd:pfam17380  466 RQQEEERKRKKLELeKEKRDRKRAEEQRRKILEKELEERKQAMieeerKRKLLEKEMEERqkaiyeeERRREAEEERRKQ 545

                          330       340       350       360       370
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1958645968 1257 QKLEERLRLLQVETASSSARAaeRSSALREEVQSLREEVEkqrvvSENLRQEL 1309
Cdd:pfam17380  546 QEMEERRRIQEQMRKATEERS--RLEAMEREREMMRQIVE-----SEKARAEY 591
PRK11281 PRK11281
mechanosensitive channel MscK;
1373-1663 5.70e-04

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 45.29  E-value: 5.70e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1373 KRFREEIEQSKQAAGGLQAELMRAQRELGELGSLRQKIVEQERAAQQLRAEKASYAEQLSMLKKAHGLLAEENRGLgerA 1452
Cdd:PRK11281    76 DRQKEETEQLKQQLAQAPAKLRQAQAELEALKDDNDEETRETLSTLSLRQLESRLAQTLDQLQNAQNDLAEYNSQL---V 152

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1453 NLgrqfleveldQAREKYVQelaAVRTDAETHLAEMRQEAQSTSrelevmtakyESAKVKVLEERQRFQEERQKLTAQVE 1532
Cdd:PRK11281   153 SL----------QTQPERAQ---AALYANSQRLQQIRNLLKGGK----------VGGKALRPSQRVLLQAEQALLNAQND 209

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1533 ELNKKLTESEQASRVQQQKLKAFQAQGGESQQEVQCLQTQLSELQAQLSQKeQAAEhyKLQMEKAkthydAKKQQNQELR 1612
Cdd:PRK11281   210 LQRKSLEGNTQLQDLLQKQRDYLTARIQRLEHQLQLLQEAINSKRLTLSEK-TVQE--AQSQDEA-----ARIQANPLVA 281

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1958645968 1613 EQLQDLEQLQKDnkeLRSETERLGrELQQAGLKTKE----AEQACRHLTAQVRSL 1663
Cdd:PRK11281   282 QELEINLQLSQR---LLKATEKLN-TLTQQNLRVKNwldrLTQSERNIKEQISVL 332
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 244-1031 6.38e-04

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 45.11  E-value: 6.38e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  244 EKDAQIAMMQQRIDHLALLNEKQAASPQEP-----SELEELRGK--------------NESLTVRLHETLKQCQNLKTEK 304
Cdd:pfam15921   82 EYSHQVKDLQRRLNESNELHEKQKFYLRQSvidlqTKLQEMQMErdamadirrresqsQEDLRNQLQNTVHELEAAKCLK 161

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  305 NQM----DRKISQLSEENGDLSFKVREFANHLQQLQGAFNDLIEEHSKASqewaekQAHLESELSTALQDKKCLEEKSEI 380
Cdd:pfam15921  162 EDMledsNTQIEQLRKMMLSHEGVLQEIRSILVDFEEASGKKIYEHDSMS------TMHFRSLGSAISKILRELDTEISY 235

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  381 LQEKISQLEDRAAQLQgSPAPEKGEVLGDALQlDTLKQEAAKLATDNTELQARVETLECERGKQEAQLLAERGHFEEEKR 460
Cdd:pfam15921  236 LKGRIFPVEDQLEALK-SESQNKIELLLQQHQ-DRIEQLISEHEVEITGLTEKASSARSQANSIQSQLEIIQEQARNQNS 313

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  461 QLASLVADLQSSVSNLSQAKEELQQASQAQGAQLTAQL----ASLTALNATLQQQDQELTSLKEQAKKeqaqMLQTLQEQ 536
Cdd:pfam15921  314 MYMRQLSDLESTVSQLRSELREAKRMYEDKIEELEKQLvlanSELTEARTERDQFSQESGNLDDQLQK----LLADLHKR 389

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  537 EQAAQGLRQQVEQLSSSlKLKEQQLEEAAKEQEAARQDHAQQLATIVEAREASV-----RERDAARQQLETLEKEKD--A 609
Cdd:pfam15921  390 EKELSLEKEQNKRLWDR-DTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSECqgqmeRQMAAIQGKNESLEKVSSltA 468

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  610 KLESLQQQLQASNEARDTAQTSVTQAQREKAELSQKIGELHACIEAAHQEQRQAQAHVTELEAQLKAEQQKATEREKVVQ 689
Cdd:pfam15921  469 QLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQEKERAIEATNAEITKLRSRVDLKLQELQHLKNEGDHLRNVQT 548

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  690 EKVQLQEQLQALEETLKIVRGSLEEekcrAADALKEQQRHATEMEAETRHLMEQREQEQKELEQEKAERKGLEARLQQLe 769
Cdd:pfam15921  549 ECEALKLQMAEKDKVIEILRQQIEN----MTQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQEFKILKDKKDAKIREL- 623

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  770 EAHQAETEALRHELAGATAAQHGA----ESEREQLLREVESWQKRVEARQQEEARYGAMFQEQLMALKGEHGKIGQEEQK 845
Cdd:pfam15921  624 EARVSDLELEKVKLVNAGSERLRAvkdiKQERDQLLNEVKTSRNELNSLSEDYEVLKRNFRNKSEEMETTTNKLKMQLKS 703

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  846 EAGEIHGEGQTGQQQSQLAQLHACLAKALQ-QVQEKEARAQKLLDDLSALREKMAATNKEvaclkalvlkageqqaaaSH 924
Cdd:pfam15921  704 AQSELEQTRNTLKSMEGSDGHAMKVAMGMQkQITAKRGQIDALQSKIQFLEEAMTNANKE------------------KH 765

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  925 ELKEPPRAGNQEsdweeeqarplgstqaaLKAVQREAEQMGGELERLRAalmqsqgqqQEVRGQQEREVARLTQERGQAQ 1004
Cdd:pfam15921  766 FLKEEKNKLSQE-----------------LSTVATEKNKMAGELEVLRS---------QERRLKEKVANMEVALDKASLQ 819

                          810       820       830
                   ....*....|....*....|....*....|
gi 1958645968 1005 ADLAQEKAAKAELE---MRLQNTLNEQRVE 1031
Cdd:pfam15921  820 FAECQDIIQRQEQEsvrLKLQHTLDVKELQ 849
Surf_Exclu_PgrA TIGR04320
SEC10/PgrA surface exclusion domain; This model describes a conserved domain found in surface ...
 608-702 6.81e-04

SEC10/PgrA surface exclusion domain; This model describes a conserved domain found in surface proteins of a number of Firmutes. Many members have LPXTG C-terminal anchoring motifs and a substantial number have the KxYKxGKxW putative sorting signal at the N-terminus. The tetracycline resistance plasmid pCF10 in Enterococcus faecalis promotes conjugal plasmid transfer in response to sex pheromones, but PgrA/Sec10 encoded by that plasmid, a member of this family, specifically inhibits the ability of cells to receive homologous plasmids. The phenomenon is called surface exclusion.


Pssm-ID: 275124 [Multi-domain]  Cd Length: 356  Bit Score: 44.33  E-value: 6.81e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  608 DAKLESLQQQLQASNEARDTAQTSVTQAQREKAELSQKIGELHACIEAAHQEQRQ-AQAHVTELEAQLK-AEQQKATERE 685
Cdd:TIGR04320  260 QAKLATAQADLAAAQTALNTAQAALTSAQTAYAAAQAALATAQKELANAQAQALQtAQNNLATAQAALAnAEARLAKAKE 339

                           90
                   ....*....|....*..
gi 1958645968  686 KVVQEKVQLQEQLQALE 702
Cdd:TIGR04320  340 ALANLNADLAKKQAALD 356
PRK10929 PRK10929
putative mechanosensitive channel protein; Provisional
 771-1059 7.55e-04

putative mechanosensitive channel protein; Provisional


Pssm-ID: 236798 [Multi-domain]  Cd Length: 1109  Bit Score: 44.66  E-value: 7.55e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  771 AHQAETEALRHELAGATAAQHGAESEREQLLREVESW-------QKRVEARQQEEARYGAMFQE---QLMALKGEHGKIg 840
Cdd:PRK10929    20 ATAPDEKQITQELEQAKAAKTPAQAEIVEALQSALNWleerkgsLERAKQYQQVIDNFPKLSAElrqQLNNERDEPRSV- 98

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  841 qEEQKEAGEIhgEGQTGQQQSQLAQLhaclAKALQQVQEkeaRAQKLLDDLSALrekmaatnkevaclkalvlkaGEQQA 920
Cdd:PRK10929    99 -PPNMSTDAL--EQEILQVSSQLLEK----SRQAQQEQD---RAREISDSLSQL---------------------PQQQT 147

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  921 AASHELKEPPR----AGNQESDWEEEQARPLGSTQAALKAVQREAE--QMGG----ELERLRAALMQSQGQQ-----QEV 985
Cdd:PRK10929   148 EARRQLNEIERrlqtLGTPNTPLAQAQLTALQAESAALKALVDELElaQLSAnnrqELARLRSELAKKRSQQldaylQAL 227

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  986 RG------QQEREVARLTQERGQAQ-ADLAQEKAAKAELEMRLQNTLNEQ--RVEFAALQEALTHAMTEKegKDQELAKL 1056
Cdd:PRK10929   228 RNqlnsqrQREAERALESTELLAEQsGDLPKSIVAQFKINRELSQALNQQaqRMDLIASQQRQAASQTLQ--VRQALNTL 305


                   ...
gi 1958645968 1057 REQ 1059
Cdd:PRK10929   306 REQ 308
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1405-1622 7.57e-04

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 44.62  E-value: 7.57e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1405 SLRQKIVEQERAAQQLRAEKASYAEQL-------SMLKKAHGLLAEENRGLGERANLGRqfLEVELDQAREKYvQELAAV 1477
Cdd:COG3206    165 NLELRREEARKALEFLEEQLPELRKELeeaeaalEEFRQKNGLVDLSEEAKLLLQQLSE--LESQLAEARAEL-AEAEAR 241

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1478 RTDAETHLAEMRQEAQ--STSRELEVMTAKYESAKVKVLEERQRFQEE---RQKLTAQVEELNKKLTESeqasrvQQQKL 1552
Cdd:COG3206    242 LAALRAQLGSGPDALPelLQSPVIQQLRAQLAELEAELAELSARYTPNhpdVIALRAQIAALRAQLQQE------AQRIL 315

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1958645968 1553 KAFQAQGGESQQEVQCLQTQLSELQAQLSQ-KEQAAEHYKLQMEkakthYDAKKQQNQELREQLQDLEQLQ 1622
Cdd:COG3206    316 ASLEAELEALQAREASLQAQLAQLEARLAElPELEAELRRLERE-----VEVARELYESLLQRLEEARLAE 381
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 931-1341 7.88e-04

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 44.72  E-value: 7.88e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  931 RAGNQESDWEEeQARPLGSTQAALKAVQREAEQM-GGELERLRAALMQSQGQQQEVRGQQERevarLTQERGQAQADLAQ 1009
Cdd:pfam15921  307 QARNQNSMYMR-QLSDLESTVSQLRSELREAKRMyEDKIEELEKQLVLANSELTEARTERDQ----FSQESGNLDDQLQK 381

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1010 EKA--AKAELEMRLQNTLNeQRVEFAALQEALTHAMTEKEGKDQELaklreqeaaQISELKALQQTLEELKKKEKEHPTG 1087
Cdd:pfam15921  382 LLAdlHKREKELSLEKEQN-KRLWDRDTGNSITIDHLRRELDDRNM---------EVQRLEALLKAMKSECQGQMERQMA 451

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1088 GARGEDASGDGPGSqlhTPGKTEAPGPEVEALRAEISKLERQWQQQQQQVEGLTHSL-ESERACRAeQDKALETLQGQLE 1166
Cdd:pfam15921  452 AIQGKNESLEKVSS---LTAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTASLqEKERAIEA-TNAEITKLRSRVD 527

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1167 EKARELGHNQAAS---ASAQRELQALRAKAQDHSKAEEEWKAQVARGQQEAERKSSLISSLEEEVSILNRQVLEKEGESK 1243
Cdd:pfam15921  528 LKLQELQHLKNEGdhlRNVQTECEALKLQMAEKDKVIEILRQQIENMTQLVGQHGRTAGAMQVEKAQLEKEINDRRLELQ 607

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1244 ELKRLVVAESEKSQKLEERLRLLQVETASSSARAAERSSALRE----------EVQSLREEV----EKQRVVSENLRQEL 1309
Cdd:pfam15921  608 EFKILKDKKDAKIRELEARVSDLELEKVKLVNAGSERLRAVKDikqerdqllnEVKTSRNELnslsEDYEVLKRNFRNKS 687

                          410       420       430
                   ....*....|....*....|....*....|..
gi 1958645968 1310 ASQAERAEESGQELKAWQEKFFQKEQALSALQ 1341
Cdd:pfam15921  688 EEMETTTNKLKMQLKSAQSELEQTRNTLKSME 719
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 1116-1699 8.83e-04

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 44.56  E-value: 8.83e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1116 VEALRAEISKLERQWQQQQQQVEGLTHSLESERACRAEQDKALETLQGQLEEKARELGHNQAASASAQRELQAL-RAKAQ 1194
Cdd:COG3096    349 IERYQEDLEELTERLEEQEEVVEEAAEQLAEAEARLEAAEEEVDSLKSQLADYQQALDVQQTRAIQYQQAVQALeKARAL 428

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1195 D-----HSKAEEEWKAQVARGQQEAERKsslISSLEEEVSILNRQVLEKEgESKELKRLVVAESEKSQKLEERLRLLqvE 1269
Cdd:COG3096    429 CglpdlTPENAEDYLAAFRAKEQQATEE---VLELEQKLSVADAARRQFE-KAYELVCKIAGEVERSQAWQTARELL--R 502

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1270 TASSSARAAERSSALREEVQSLREEVEKQRVVsENLRQELASQAERAEESGQELKAWQEkffQKEQALSALQLEHTSTQA 1349
Cdd:COG3096    503 RYRSQQALAQRLQQLRAQLAELEQRLRQQQNA-ERLLEEFCQRIGQQLDAAEELEELLA---ELEAQLEELEEQAAEAVE 578

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1350 LVSELlpakhlcqqlqAEQAAAEKRFREEIEQSKQAAGGLQAELMRAQRELGE-------LGSLRQKIVEQERAAQ---- 1418
Cdd:COG3096    579 QRSEL-----------RQQLEQLRARIKELAARAPAWLAAQDALERLREQSGEaladsqeVTAAMQQLLEREREATverd 647

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1419 QLRAEKASYAEQLSMLKKAHGLLAEENRGLGERAN---LGRQFLEVELDQARE---KY--------VQELAAVRT----- 1479
Cdd:COG3096    648 ELAARKQALESQIERLSQPGGAEDPRLLALAERLGgvlLSEIYDDVTLEDAPYfsaLYgparhaivVPDLSAVKEqlagl 727

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1480 -DAETHLAEMRQEAQS---TSRELEVMtakyESAKVKVLEERQ----RF----------QEER-QKLTAQVEELNKKLTE 1540
Cdd:COG3096    728 eDCPEDLYLIEGDPDSfddSVFDAEEL----EDAVVVKLSDRQwrysRFpevplfgraaREKRlEELRAERDELAEQYAK 803

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1541 SEQASRVQQ---QKLKAFQAQG------GESQQEVQCLQTQLSELQAQLSQKEQAAEHYklqmekakthydakKQQNQEL 1611
Cdd:COG3096    804 ASFDVQKLQrlhQAFSQFVGGHlavafaPDPEAELAALRQRRSELERELAQHRAQEQQL--------------RQQLDQL 869

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1612 REQLQDLEQLQK-----DNKELRSETERLGRELQQAglktKEAEQACRHLTAQVRSLEAQVAHADQQLRDLGKFQVATDA 1686
Cdd:COG3096    870 KEQLQLLNKLLPqanllADETLADRLEELREELDAA----QEAQAFIQQHGKALAQLEPLVAVLQSDPEQFEQLQADYLQ 945

                          650
                   ....*....|...
gi 1958645968 1687 LKSREPQVKPQLD 1699
Cdd:COG3096    946 AKEQQRRLKQQIF 958
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1472-1722 9.19e-04

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 44.26  E-value: 9.19e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1472 QELAAVRTDAEtHLAEMRQEAQSTSRELEVMTAKYESAkvkvLEERQRFQEERQKLTAQVEELNKKLTESEQASRVQQQK 1551
Cdd:PRK02224   213 SELAELDEEIE-RYEEQREQARETRDEADEVLEEHEER----REELETLEAEIEDLRETIAETEREREELAEEVRDLRER 287

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1552 LKAFQAQGGESQQEVQCLQTQLSELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQELREQLQDLEQlqkDNKELRSE 1631
Cdd:PRK02224   288 LEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLEE---RAEELREE 364

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1632 TERLGRELQQAGLKTKEAEQACRHLTAQVRSLEAQVAHADQQLRDLGKFQVATDALKSREPQVKPQLDLSIDSLDLSLEE 1711
Cdd:PRK02224   365 AAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAELEATLRTARERVEE 444

                          250
                   ....*....|.
gi 1958645968 1712 GTPCSVASKLP 1722
Cdd:PRK02224   445 AEALLEAGKCP 455
PRK09039 PRK09039
peptidoglycan -binding protein;
599-721 9.52e-04

peptidoglycan -binding protein;


Pssm-ID: 181619 [Multi-domain]  Cd Length: 343  Bit Score: 43.80  E-value: 9.52e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  599 QLETLEKEKDAKLESLQQQLQASNEA----RDTAQTSVTQAQREKAELSQKIGELHACIEAAHQEQRQAQAHVTELEAQL 674
Cdd:PRK09039    67 DLLSLERQGNQDLQDSVANLRASLSAaeaeRSRLQALLAELAGAGAAAEGRAGELAQELDSEKQVSARALAQVELLNQQI 146

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|....*..
gi 1958645968  675 KAeqqkaterekvvqekvqLQEQLQALEETLKIVRGSLEEEKCRAAD 721
Cdd:PRK09039   147 AA-----------------LRRQLAALEAALDASEKRDRESQAKIAD 176
Surf_Exclu_PgrA TIGR04320
SEC10/PgrA surface exclusion domain; This model describes a conserved domain found in surface ...
 461-561 9.72e-04

SEC10/PgrA surface exclusion domain; This model describes a conserved domain found in surface proteins of a number of Firmutes. Many members have LPXTG C-terminal anchoring motifs and a substantial number have the KxYKxGKxW putative sorting signal at the N-terminus. The tetracycline resistance plasmid pCF10 in Enterococcus faecalis promotes conjugal plasmid transfer in response to sex pheromones, but PgrA/Sec10 encoded by that plasmid, a member of this family, specifically inhibits the ability of cells to receive homologous plasmids. The phenomenon is called surface exclusion.


Pssm-ID: 275124 [Multi-domain]  Cd Length: 356  Bit Score: 43.56  E-value: 9.72e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  461 QLASLVADLQSSVSNLSQAKEELqqasQAQGAQLTAQLASLTALNATLQQQDQELTSLKEQAKKEQAQMLQTLQEQEQAA 540
Cdd:TIGR04320  255 SLAALQAKLATAQADLAAAQTAL----NTAQAALTSAQTAYAAAQAALATAQKELANAQAQALQTAQNNLATAQAALANA 330

                           90       100
                   ....*....|....*....|....*
gi 1958645968  541 QG----LRQQVEQLSSSLKLKEQQL 561
Cdd:TIGR04320  331 EArlakAKEALANLNADLAKKQAAL 355
MARTX_Nterm NF012221
MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model ...
 341-648 1.07e-03

MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin N-terminal region; This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.


Pssm-ID: 467957 [Multi-domain]  Cd Length: 1848  Bit Score: 44.44  E-value: 1.07e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  341 DLIEEHSKASQEWAEKQAHLESELST--ALQDKKCLEEKSEIL-QEKISQLEDRA---AQLQgSPAPEKGEVLGDAlQLD 414
Cdd:NF012221  1532 DNVVATSESSQQADAVSKHAKQDDAAqnALADKERAEADRQRLeQEKQQQLAAISgsqSQLE-STDQNALETNGQA-QRD 1609

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  415 TLKQEAAKLATDNTELQARVETLEcergkQEAQLLAERGhfEEEKRQLA-SLVADLQSSVSNlsqakeelqqasqaqgaq 493
Cdd:NF012221  1610 AILEESRAVTKELTTLAQGLDALD-----SQATYAGESG--DQWRNPFAgGLLDRVQEQLDD------------------ 1664

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  494 ltAQLASLTALNATLQQQDQELTSLKEQAKKEQAQMLQTLQEQEQAAQGLRQQveqlssslklkeqqleeaakeqeaarq 573
Cdd:NF012221  1665 --AKKISGKQLADAKQRHVDNQQKVKDAVAKSEAGVAQGEQNQANAEQDIDDA--------------------------- 1715

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1958645968  574 dhaqqlativeAREASVRERDAARQQLETLEKEKDAKLESLQQQLQASNEARdTAQTSVTQAQREKAELSQKIGE 648
Cdd:NF012221  1716 -----------KADAEKRKDDALAKQNEAQQAESDANAAANDAQSRGEQDAS-AAENKANQAQADAKGAKQDESD 1778
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
949-1214 1.16e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 43.85  E-value: 1.16e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  949 STQAALKAVQREAEQMGGELERLRAALMQSQGQQQEVRGQQEREVarLTQERGQAQADLAQEKAAKAELEMRLQNTLNEQ 1028
Cdd:COG3206    172 EARKALEFLEEQLPELRKELEEAEAALEEFRQKNGLVDLSEEAKL--LLQQLSELESQLAEARAELAEAEARLAALRAQL 249

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1029 RVEFAALQEALThamtekegkDQELAKLREQEAAQISELKALQQTLeelkkkekehptggargedasgdGPGSqlhtpgk 1108
Cdd:COG3206    250 GSGPDALPELLQ---------SPVIQQLRAQLAELEAELAELSARY-----------------------TPNH------- 290

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1109 teapgPEVEALRAEISKLERQWQQQQQQVEGlthSLESERACRAEQDKALETLQGQLEEKARELGHNQAASASAQRELQA 1188
Cdd:COG3206    291 -----PDVIALRAQIAALRAQLQQEAQRILA---SLEAELEALQAREASLQAQLAQLEARLAELPELEAELRRLEREVEV 362

                          250       260
                   ....*....|....*....|....*.
gi 1958645968 1189 LRAKAQDHSKAEEEwkAQVARGQQEA 1214
Cdd:COG3206    363 ARELYESLLQRLEE--ARLAEALTVG 386
PRK09039 PRK09039
peptidoglycan -binding protein;
1521-1642 1.16e-03

peptidoglycan -binding protein;


Pssm-ID: 181619 [Multi-domain]  Cd Length: 343  Bit Score: 43.42  E-value: 1.16e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1521 QEERQKLTAQVEELNKKLTESEQASRVQQQKLKAFQAQGGESQQEVQCLQTQLSELQAQLSQ-------KEQAAEHYKLQ 1593
Cdd:PRK09039    52 DSALDRLNSQIAELADLLSLERQGNQDLQDSVANLRASLSAAEAERSRLQALLAELAGAGAAaegrageLAQELDSEKQV 131

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|...
gi 1958645968 1594 MEKAKTHYDAKKQQNQELREQLQDLEQL----QKDNKELRSETERLGRELQQA 1642
Cdd:PRK09039   132 SARALAQVELLNQQIAALRRQLAALEAAldasEKRDRESQAKIADLGRRLNVA 184
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 1255-1668 1.23e-03

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 44.19  E-value: 1.23e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1255 KSQKLEERLRLLQVETASSSARAAERSSALREEVQSLREEVEKQRVVSENLRQELASQAERA--EESGQELKAWQEKFFQ 1332
Cdd:TIGR00618  195 KAELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHLREALQQTQQSHAYLTQKREAQEEQLkkQQLLKQLRARIEELRA 274

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1333 KEQALSALQLEHTSTQALVSELLPAKHL--CQQLQAEQAAAEKRFREEIEQSKQAAGGLQAELMRAQRELGELGSLRQKI 1410
Cdd:TIGR00618  275 QEAVLEETQERINRARKAAPLAAHIKAVtqIEQQAQRIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQE 354

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1411 VEQERAAQQLRAEKASYAEQLSMLKKAHGlLAEENRGLGERANLGRQFLEVE---------LDQAREKYVQELAAVRTDA 1481
Cdd:TIGR00618  355 IHIRDAHEVATSIREISCQQHTLTQHIHT-LQQQKTTLTQKLQSLCKELDILqreqatidtRTSAFRDLQGQLAHAKKQQ 433

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1482 ETHLAEMRQEAQSTSRELEVMTAKyesaKVKVLEERQRFQEERQKLtAQVEELNKKLTESEQASRVQQQKLKAFQAQGGE 1561
Cdd:TIGR00618  434 ELQQRYAELCAAAITCTAQCEKLE----KIHLQESAQSLKEREQQL-QTKEQIHLQETRKKAVVLARLLELQEEPCPLCG 508

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1562 S------------------------QQEVQCLQTQLSELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQELREQ--- 1614
Cdd:TIGR00618  509 ScihpnparqdidnpgpltrrmqrgEQTYAQLETSEEDVYHQLTSERKQRASLKEQMQEIQQSFSILTQCDNRSKEDipn 588

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|....
gi 1958645968 1615 LQDLEQLQKDNKELRSETERLGRELQQAGLKTKEAEQACRHLTAQVRSLEAQVA 1668
Cdd:TIGR00618  589 LQNITVRLQDLTEKLSEAEDMLACEQHALLRKLQPEQDLQDVRLHLQQCSQELA 642
MreC COG1792
Cell shape-determining protein MreC [Cell cycle control, cell division, chromosome ...
 1599-1660 1.48e-03

Cell shape-determining protein MreC [Cell cycle control, cell division, chromosome partitioning, Cytoskeleton];


Pssm-ID: 441397  Cd Length: 282  Bit Score: 42.95  E-value: 1.48e-03
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1958645968 1599 THYDAKKQQNQELREQLQDLEQLQKDNKELRSETERLgRELqqagLKTKEAEQAcRHLTAQV 1660
Cdd:COG1792     68 RSLFNLREENERLKEENAELRAELQRLEELEAENARL-REL----LDLKERLDY-KFVAAEV 123
mukB PRK04863
chromosome partition protein MukB;
328-658 1.50e-03

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 43.79  E-value: 1.50e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  328 FANHLQQLQGAFNDL---IEEHSKASQEWAEKQAHLESELSTALQDKKCLEEKSEILQEKISQLEDRAAQL-QGSPAPEK 403
Cdd:PRK04863   346 QQEKIERYQADLEELeerLEEQNEVVEEADEQQEENEARAEAAEEEVDELKSQLADYQQALDVQQTRAIQYqQAVQALER 425

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  404 GEVLgdaLQLDTLkqEAAKLATDNTELQARVETLECERGKQEAQLL---AERGHFEEEKRQLASLVADLQSSVSNlSQAK 480
Cdd:PRK04863   426 AKQL---CGLPDL--TADNAEDWLEEFQAKEQEATEELLSLEQKLSvaqAAHSQFEQAYQLVRKIAGEVSRSEAW-DVAR 499

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  481 EELQqasqaqgaqltaQLASLTALNATLQQQDQELTSLKeqakkeqaqmlQTLQEQeQAAQGLRQQVEQLSSSLKLKEQQ 560
Cdd:PRK04863   500 ELLR------------RLREQRHLAEQLQQLRMRLSELE-----------QRLRQQ-QRAERLLAEFCKRLGKNLDDEDE 555

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  561 LEEAAKEQEAARQDHAQQLATIVEAREASVRERDAARQQLETLEK------EKDAKLESLQQQL-------QASNEARDT 627
Cdd:PRK04863   556 LEQLQEELEARLESLSESVSEARERRMALRQQLEQLQARIQRLAArapawlAAQDALARLREQSgeefedsQDVTEYMQQ 635

                          330       340       350
                   ....*....|....*....|....*....|.
gi 1958645968  628 AQTSVTQAQREKAELSQKIGELHACIEAAHQ 658
Cdd:PRK04863   636 LLERERELTVERDELAARKQALDEEIERLSQ 666
mukB PRK04863
chromosome partition protein MukB;
1117-1700 1.60e-03

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 43.79  E-value: 1.60e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1117 EALRAEISKLERQWQQQQQQVEGLTHSLESERACRAEQDKaLETLQGQLEEKARELGHNQAASASAQRELQALRAKAQDH 1196
Cdd:PRK04863   310 VEMARELAELNEAESDLEQDYQAASDHLNLVQTALRQQEK-IERYQADLEELEERLEEQNEVVEEADEQQEENEARAEAA 388

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1197 SKAEEEWKAQVARGQQ---EAERKSS----LISSLEEEVSILNRQVLEKEGESKELKRLVVAESEKSQK---LEERLRLL 1266
Cdd:PRK04863   389 EEEVDELKSQLADYQQaldVQQTRAIqyqqAVQALERAKQLCGLPDLTADNAEDWLEEFQAKEQEATEEllsLEQKLSVA 468

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1267 -----QVETASSSARAA----ERSSALREEVQSLREeVEKQRVVSEN----------LRQELASQAeRAEESGQELKAWQ 1327
Cdd:PRK04863   469 qaahsQFEQAYQLVRKIagevSRSEAWDVARELLRR-LREQRHLAEQlqqlrmrlseLEQRLRQQQ-RAERLLAEFCKRL 546

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1328 EKFFQKEQALSALQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKRFREEIEQSKQAAGGLQAELMRAQRELGE----- 1402
Cdd:PRK04863   547 GKNLDDEDELEQLQEELEARLESLSESVSEARERRMALRQQLEQLQARIQRLAARAPAWLAAQDALARLREQSGEefeds 626

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1403 --LGSLRQKIVEQERAAQQ----LRAEKASYAEQLSMLKKAHGLLAEENRGLGERAN---LGRQFLEVELDQAREK---- 1469
Cdd:PRK04863   627 qdVTEYMQQLLERERELTVerdeLAARKQALDEEIERLSQPGGSEDPRLNALAERFGgvlLSEIYDDVSLEDAPYFsaly 706

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1470 -------YVQELAAVRTDAET----------------HLAEMRQEAQSTSRELEVMTAKYESAKVKVLEERQRFQEERQK 1526
Cdd:PRK04863   707 gparhaiVVPDLSDAAEQLAGledcpedlyliegdpdSFDDSVFSVEELEKAVVVKIADRQWRYSRFPEVPLFGRAAREK 786

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1527 LTAQV-EELNKKLTESEQASRVQQ------QKLKAFQAQ------GGESQQEVQCLQTQLSELQAQLSQKEQAAEHYKLQ 1593
Cdd:PRK04863   787 RIEQLrAEREELAERYATLSFDVQklqrlhQAFSRFIGShlavafEADPEAELRQLNRRRVELERALADHESQEQQQRSQ 866

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1594 MEKAKthydakkqqnqelrEQLQDLEQLQKDNKELRSETerLGRELQQAGLKTKEAEQACRHLT---AQVRSLEAQVAHA 1670
Cdd:PRK04863   867 LEQAK--------------EGLSALNRLLPRLNLLADET--LADRVEEIREQLDEAEEAKRFVQqhgNALAQLEPIVSVL 930

                          650       660       670
                   ....*....|....*....|....*....|
gi 1958645968 1671 DQQLRDLGKFQVATDALKSREPQVKPQLDL 1700
Cdd:PRK04863   931 QSDPEQFEQLKQDYQQAQQTQRDAKQQAFA 960
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 1515-1642 2.04e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 41.83  E-value: 2.04e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1515 EERQRFQEERQKLTAQVEELNKKLTESEQASRVQQQKLKAFQAQGGE--SQQEVQCLQTQLSELQAQLSQKEQAAEHYKL 1592
Cdd:COG1579     38 DELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNvrNNKEYEALQKEIESLKRRISDLEDEILELME 117

                           90       100       110       120       130
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1958645968 1593 QMEKAKTHYDAKKQQNQELREQLQDLE-QLQKDNKELRSETERLGRELQQA 1642
Cdd:COG1579    118 RIEELEEELAELEAELAELEAELEEKKaELDEELAELEAELEELEAEREEL 168
PHA03307 PHA03307
transcriptional regulator ICP4; Provisional
 1713-1996 2.08e-03

transcriptional regulator ICP4; Provisional


Pssm-ID: 223039 [Multi-domain]  Cd Length: 1352  Bit Score: 43.24  E-value: 2.08e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1713 TPCSVASKLPRTQPDGTSVPGEPASPISQRlPPKVESLESLYFTPIPARGQA--PLETSLDSLGDAFPDSGRKTRSARRR 1790
Cdd:PHA03307   179 PEETARAPSSPPAEPPPSTPPAAASPRPPR-RSSPISASASSPAPAPGRSAAddAGASSSDSSSSESSGCGWGPENECPL 257

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1791 TTQIINITMTKKLELEEPDsaNSSFYSTQSAPASQANLRATSSTQSLARLGSPDDSNSALLSLPGYRP-----TTRSSAR 1865
Cdd:PHA03307   258 PRPAPITLPTRIWEASGWN--GPSSRPGPASSSSSPRERSPSPSPSSPGSGPAPSSPRASSSSSSSREsssssTSSSSES 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1866 RSQTRTSSGAPHGRNsfymGTCQDEPeqvdDWNRIAELQQRNRvcpphlktcypleSRPALSLATITdeemktgDPRETL 1945
Cdd:PHA03307   336 SRGAAVSPGPSPSRS----PSPSRPP----PPADPSSPRKRPR-------------PSRAPSSPAAS-------AGRPTR 387

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|.
gi 1958645968 1946 RRASMQPAQIAEGAGITTRQQRKRVSSETHQGPGTPESKKATscfPRPMTP 1996
Cdd:PHA03307   388 RRARAAVAGRARRRDATGRFPAGRPRPSPLDAGAASGAFYAR---YPLLTP 435
CHASE3 COG5278
Extracytoplasmic sensor domain CHASE3 (specificity unknown) [Signal transduction mechanisms];
496-906 2.30e-03

Extracytoplasmic sensor domain CHASE3 (specificity unknown) [Signal transduction mechanisms];


Pssm-ID: 444089 [Multi-domain]  Cd Length: 530  Bit Score: 42.97  E-value: 2.30e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  496 AQLASLTALNATLQQQDQELTSLKEQAKKEQAQMLQTLQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEAARQDH 575
Cdd:COG5278    107 ARLDELEALIDQWLAELEQVIALRRAGGLEAALALVRSGEGKALMDEIRARLLLLALALAALLLAAAALLLLLLALAALL 186

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  576 AQQLATIVEAREASVRERDAARQQLETLEKEKDAKLESLQQQLQASNEARDTAQTSVTQAQREKAELSQKIGELHACIEA 655
Cdd:COG5278    187 ALAELLLLALARALAALLLLLLLEAELAAAAALLAAAAALAALAALELLAALALALALLLAALLLALLAALALAALLAAA 266

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  656 AHQEQRQAQAHVTELEAQLKAEQQKATEREKVVQEKVQLQEQLQALEETLKIVRGSLEEEKCRAADALKEQQRHATEMEA 735
Cdd:COG5278    267 LLALAALLLALAAAAALAAAAALELAAAEALALAELELELLLAAAAAAAAAAAAAAAALAALLALALATALAAAAAALAL 346

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  736 ETRHLMEQREQEQKELEQEKAERKGLEARLQQLEEAHQAETEALRHELAGATAAQHGAESEREQLLREVESWQKRVEARQ 815
Cdd:COG5278    347 LAALLAEAAAAAAEEAEAAAEAAAAALAGLAEVEAEGAAEAVELEVLAIAAAAAAAAAEAAAAAAAAAAASAAEALELAE 426

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  816 QEEARYGAMFQEQLMALKGEHGKIGQEEQKEAGEIHGEGQTGQQQSQLAQLHACLAKALQQVQEKEARAQKLLDDLSALR 895
Cdd:COG5278    427 ALAEALALAEEEALALAAASSELAEAGAALALAAAEALAEELAAVAALAALAAAAAALAEAEAAAALAAAAALSLALALA 506

                          410
                   ....*....|.
gi 1958645968  896 EKMAATNKEVA 906
Cdd:COG5278    507 ALLLAAAEAAL 517
mukB PRK04863
chromosome partition protein MukB;
1271-1667 2.46e-03

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 43.02  E-value: 2.46e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1271 ASSSARAAERSSALREEVQSLREEVEKQRVvsenlrqELASQAERAEESGQELKAWQEkffqkeqALSALQLEHTST--- 1347
Cdd:PRK04863   271 AADYMRHANERRVHLEEALELRRELYTSRR-------QLAAEQYRLVEMARELAELNE-------AESDLEQDYQAAsdh 336

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1348 QALVSELLPAKHLCQQLQAEQAAAEKRFREEIEQSKQAAGGL---QAELMRAQRELGELGS----LRQKIVEQERAAQQL 1420
Cdd:PRK04863   337 LNLVQTALRQQEKIERYQADLEELEERLEEQNEVVEEADEQQeenEARAEAAEEEVDELKSqladYQQALDVQQTRAIQY 416

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1421 RAEKASY--AEQLSML-----KKAHGLLAE---ENRGLGERANLGRQFLEVElDQAREKYVQELAAVRTDAethlAEM-R 1489
Cdd:PRK04863   417 QQAVQALerAKQLCGLpdltaDNAEDWLEEfqaKEQEATEELLSLEQKLSVA-QAAHSQFEQAYQLVRKIA----GEVsR 491

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1490 QEAQSTSRELEvmtakyesakvkvleerqRFQEERQKLTAQVEELNKKLTESEQASRVQQQKLKAFQAQGGESQQEVQcl 1569
Cdd:PRK04863   492 SEAWDVARELL------------------RRLREQRHLAEQLQQLRMRLSELEQRLRQQQRAERLLAEFCKRLGKNLD-- 551

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1570 qtQLSELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQELREQLQDLEQLQKDNKELRSETERLGRE----------- 1638
Cdd:PRK04863   552 --DEDELEQLQEELEARLESLSESVSEARERRMALRQQLEQLQARIQRLAARAPAWLAAQDALARLREQsgeefedsqdv 629

                          410       420       430
                   ....*....|....*....|....*....|..
gi 1958645968 1639 ---LQQAGLKTKEAEQACRHLTAQVRSLEAQV 1667
Cdd:PRK04863   630 teyMQQLLERERELTVERDELAARKQALDEEI 661
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 211-768 2.78e-03

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 42.85  E-value: 2.78e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  211 QFQMRRLKKQLADERNNRDELELELSESLKLLTEKDAQIAMMQQRIDHLA----LLNEKQAASPQEPSELEE-------L 279
Cdd:pfam01576  102 QQHIQDLEEQLDEEEAARQKLQLEKVTTEAKIKKLEEDILLLEDQNSKLSkerkLLEERISEFTSNLAEEEEkakslskL 181

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  280 RGKNESLTVRLHETLKQC----QNLKTEKNQMDRKISQLSEENGDLSFKVREFANHLQQ----LQGAFNDLIEEHSKASQ 351
Cdd:pfam01576  182 KNKHEAMISDLEERLKKEekgrQELEKAKRKLEGESTDLQEQIAELQAQIAELRAQLAKkeeeLQAALARLEEETAQKNN 261

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  352 ----------EWAEKQAHLESEL---STALQDKKCLEEKSEILQEKISQLEDRAAQLQGSPAPEKGEVlgdALQLDTLKQ 418
Cdd:pfam01576  262 alkkireleaQISELQEDLESERaarNKAEKQRRDLGEELEALKTELEDTLDTTAAQQELRSKREQEV---TELKKALEE 338

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  419 EAAKLATDNTELQARVETLECERGKQEAQLLAERGHFEEEKRQLASLVADLQSSVSNLSQAKEElqqaSQAQGAQLTAQL 498
Cdd:pfam01576  339 ETRSHEAQLQEMRQKHTQALEELTEQLEQAKRNKANLEKAKQALESENAELQAELRTLQQAKQD----SEHKRKKLEGQL 414

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  499 ASLTALNATLQQQDQELTSLKEQAKKEQAQMLQTLQEQEQAAQGLRQQVEQLSSslklkeqqleeaakeqeaarqdhaqQ 578
Cdd:pfam01576  415 QELQARLSESERQRAELAEKLSKLQSELESVSSLLNEAEGKNIKLSKDVSSLES-------------------------Q 469

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  579 LATIVEAREASVRERDAARQQLETLEKEKDakleSLQQQLQASNEARDTAQTSVTQAQREKAELSQKIGELHACIEAAHQ 658
Cdd:pfam01576  470 LQDTQELLQEETRQKLNLSTRLRQLEDERN----SLQEQLEEEEEAKRNVERQLSTLQAQLSDMKKKLEEDAGTLEALEE 545

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  659 EQRQAQahvTELEAQLKAEQQKATEREKVVQEKVQLQEQLQ--------------ALEETLKIVRGSLEEEKCRAADALK 724
Cdd:pfam01576  546 GKKRLQ---RELEALTQQLEEKAAAYDKLEKTKNRLQQELDdllvdldhqrqlvsNLEKKQKKFDQMLAEEKAISARYAE 622

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*..
gi 1958645968  725 EQQR-HATEMEAETRHLMEQREQEQKELEQEKAER--KGLEARLQQL 768
Cdd:pfam01576  623 ERDRaEAEAREKETRALSLARALEEALEAKEELERtnKQLRAEMEDL 669
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1118-1325 2.78e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.44  E-value: 2.78e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1118 ALRAEISKLERQWQQQQQQVEGLTHSLESERACRAEQDKALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQDHS 1197
Cdd:COG4942     17 AQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELR 96

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1198 KAEEEWKAQVAR--------GQQ-------------EAERKSSLISSLEEEVSILNRQVLEKEGESKELKRLVVAESEKS 1256
Cdd:COG4942     97 AELEAQKEELAEllralyrlGRQpplalllspedflDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERAEL 176

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1958645968 1257 QKLEERLRLLQVETASSSARAAERSSALREEVQSLREEVEKQRVVSENLRQELASQAERAEESGQELKA 1325
Cdd:COG4942    177 EALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPA 245
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
584-1329 2.86e-03

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 42.74  E-value: 2.86e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  584 EAREASVRE------RDAARQQLETLEKEKDAKLESLQQQLQASNEARDTaqtsVTQAQREKAELSQKIGELHACIEAAH 657
Cdd:PRK03918   145 ESREKVVRQilglddYENAYKNLGEVIKEIKRRIERLEKFIKRTENIEEL----IKEKEKELEEVLREINEISSELPELR 220

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  658 QEQRQAQAHVTELEAQLKAEQQKATEREKVVQEKVQLQEQLQALEETLKIVRGSLE--EEKCRAADALKEQQRHATEMEA 735
Cdd:PRK03918   221 EELEKLEKEVKELEELKEEIEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEelEEKVKELKELKEKAEEYIKLSE 300

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  736 ETRHLMEQREQEQKELEQEKAERKGLEARLQQLEEahqaetealrhelagataaqhgAESEREQLLREVESWQKRVEARQ 815
Cdd:PRK03918   301 FYEEYLDELREIEKRLSRLEEEINGIEERIKELEE----------------------KEERLEELKKKLKELEKRLEELE 358

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  816 QEEARYgamfqEQLMALKGEHGKIGQEEQKEAGEihgegqtgqqqsqlaqlhaclaKALQQVQEKEARAQKLLDDLSALR 895
Cdd:PRK03918   359 ERHELY-----EEAKAKKEELERLKKRLTGLTPE----------------------KLEKELEELEKAKEEIEEEISKIT 411

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  896 EKMAATNKEVACLKalvlkageqqaAASHELKEP----PRAGNQESdwEEEQARPLGSTQAALKAVQREAEQMGGELERL 971
Cdd:PRK03918   412 ARIGELKKEIKELK-----------KAIEELKKAkgkcPVCGRELT--EEHRKELLEEYTAELKRIEKELKEIEEKERKL 478

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  972 RAALmqsqgqqqevrgqQEREVARLTQERGQAQADLAQE-KAAKAELEMRLQNTLNEQRVEFAALQEALTHAMTEKEGKD 1050
Cdd:PRK03918   479 RKEL-------------RELEKVLKKESELIKLKELAEQlKELEEKLKKYNLEELEKKAEEYEKLKEKLIKLKGEIKSLK 545

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1051 QELAKLREQEAAQISELKALQQTLEELkkkekehptggargedasgdgpgSQLHTpgKTEAPGPE-VEALRAEISKLERQ 1129
Cdd:PRK03918   546 KELEKLEELKKKLAELEKKLDELEEEL-----------------------AELLK--ELEELGFEsVEELEERLKELEPF 600

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1130 WQQQQQQVeglthslESERACRAEQDKaLETLQGQLEEKARELGHNQAASASAQRELQALRAKAqdhskAEEEWKaqvaR 1209
Cdd:PRK03918   601 YNEYLELK-------DAEKELEREEKE-LKKLEEELDKAFEELAETEKRLEELRKELEELEKKY-----SEEEYE----E 663

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1210 GQQEAERKSSLISSLEEEVSILNRQVLEKEGESKELKRlvvaESEKSQKLEERLRLLQvetasssaRAAERSSALREEVQ 1289
Cdd:PRK03918   664 LREEYLELSRELAGLRAELEELEKRREEIKKTLEKLKE----ELEEREKAKKELEKLE--------KALERVEELREKVK 731

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|....
gi 1958645968 1290 SLREEVEKQrvvSENLRQELASQ--AERAEE--SGQELKAWQEK 1329
Cdd:PRK03918   732 KYKALLKER---ALSKVGEIASEifEELTEGkySGVRVKAEENK 772
Crescentin pfam19220
Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament ...
 578-827 2.92e-03

Crescentin protein; This entry represents a bacterial equivalent to Intermediate Filament proteins, named crescentin, whose cytoskeletal function is required for the vibrioid and helical shapes of Caulobacter crescentus. Without crescentin, the cells adopt a straight-rod morphology. Crescentin has characteriztic features of IF proteins including the ability to assemble into filaments in vitro without energy or cofactor requirements. In vivo, crescentin forms a helical structure that colocalizes with the inner cell curvatures beneath the cytoplasmic membrane.


Pssm-ID: 437057 [Multi-domain]  Cd Length: 401  Bit Score: 42.36  E-value: 2.92e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  578 QLATIVEAREASVRERDAARQQLETLEkekdAKLESLQQQLQASNEARDTAQTSVTQAQREKAELSQKIGELHACI---E 654
Cdd:pfam19220   28 DFSQLIEPIEAILRELPQAKSRLLELE----ALLAQERAAYGKLRRELAGLTRRLSAAEGELEELVARLAKLEAALreaE 103

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  655 AAHQEQR----QAQAHVTELEAQLKAEqqkATEREKVVQEKVQLQEQLQALEETLKIVRGSLE---------EEKCRAAD 721
Cdd:pfam19220  104 AAKEELRielrDKTAQAEALERQLAAE---TEQNRALEEENKALREEAQAAEKALQRAEGELAtarerlallEQENRRLQ 180

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  722 ALKEQQ--------RHATEMEAETRHLMEQREQEQKELEQEKAERKGLEARLQQLEEAHQAETEALRHELAGATA----- 788
Cdd:pfam19220  181 ALSEEQaaelaeltRRLAELETQLDATRARLRALEGQLAAEQAERERAEAQLEEAVEAHRAERASLRMKLEALTAraaat 260

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 1958645968  789 ----------------AQHGAESEREQLLREVESWQKRVEARQQEEARYGAMFQE 827
Cdd:pfam19220  261 eqllaearnqlrdrdeAIRAAERRLKEASIERDTLERRLAGLEADLERRTQQFQE 315
PRK10246 PRK10246
exonuclease subunit SbcC; Provisional
 499-1005 3.01e-03

exonuclease subunit SbcC; Provisional


Pssm-ID: 182330 [Multi-domain]  Cd Length: 1047  Bit Score: 42.87  E-value: 3.01e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  499 ASLTALNATLQQQDQELTSLKEQAKKEQAQMLQTLQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEAARQDHAQQ 578
Cdd:PRK10246   380 EQLRQWQQQLTHAEQKLNALPAITLTLTADEVAAALAQHAEQRPLRQRLVALHGQIVPQQKRLAQLQVAIQNVTQEQTQR 459

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  579 LATIVEAREaSVRERDAARQQLETL--EKEKDAKLESLQQQLQA----------SNEARDTAQT-SVTQAQREKAELSQK 645
Cdd:PRK10246   460 NAALNEMRQ-RYKEKTQQLADVKTIceQEARIKDLEAQRAQLQAgqpcplcgstSHPAVEAYQAlEPGVNQSRLDALEKE 538

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  646 IGELhacieaahqeQRQAQAHVTELEAQLKAEQQKATEREKVVQEKVQLQEQLQALEETLKIVRGSLEEekcrAADALKE 725
Cdd:PRK10246   539 VKKL----------GEEGAALRGQLDALTKQLQRDESEAQSLRQEEQALTQQWQAVCASLNITLQPQDD----IQPWLDA 604

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  726 QQRHATEMEAETRHLMEQREQeqkeleqekAERKGLEARLQQLEEAHQAeteALRHELAgATAAQHGAESEREQLLREVE 805
Cdd:PRK10246   605 QEEHERQLRLLSQRHELQGQI---------AAHNQQIIQYQQQIEQRQQ---QLLTALA-GYALTLPQEDEEASWLATRQ 671

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  806 SWQKRVEARQQEEARygamFQEQLMALKGEHGKIGQEEQKEAG----------EIHGE-----GQTGQQQSQLAQLHACL 870
Cdd:PRK10246   672 QEAQSWQQRQNELTA----LQNRIQQLTPLLETLPQSDDLPHSeetvaldnwrQVHEQclslhSQLQTLQQQDVLEAQRL 747

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  871 AKALQQVQ---------EKEARAQKLLDDLSALREKMAATNKEVACLKALVLKAGEQQAAASHeLKEPPRAGNQESDWEE 941
Cdd:PRK10246   748 QKAQAQFDtalqasvfdDQQAFLAALLDEETLTQLEQLKQNLENQRQQAQTLVTQTAQALAQH-QQHRPDGLDLTVTVEQ 826

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1958645968  942 EQARPLGSTQAALKAVQREAEqmggelerLRAALMQSQG--QQQEVRGQQEREVARLTQERGQAQA 1005
Cdd:PRK10246   827 IQQELAQLAQQLRENTTRQGE--------IRQQLKQDADnrQQQQALMQQIAQATQQVEDWGYLNS 884
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 790-1072 3.10e-03

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 42.80  E-value: 3.10e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  790 QHGAESEREQLLREVESWQKRVEArqqEEARYGAMfqEQLMALKGEHGKIGQEEQKEAGEIHGEgqtgQQQSQLAQLHac 869
Cdd:pfam17380  298 QERLRQEKEEKAREVERRRKLEEA---EKARQAEM--DRQAAIYAEQERMAMERERELERIRQE----ERKRELERIR-- 366

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  870 lakalqqvQEKEARAQKLLDDLSALREKMAATNKEVAclkalvlkaGEQQAAASHELKEPPRAGNQESDWEEEQARPLGS 949
Cdd:pfam17380  367 --------QEEIAMEISRMRELERLQMERQQKNERVR---------QELEAARKVKILEEERQRKIQQQKVEMEQIRAEQ 429

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  950 TQAALKAVQREAEQMGGELERLRAALMQSQGQQQEVRGQQ-EREVARLTQERGQAQADLAQE---KAAKAELEMRLQNTL 1025
Cdd:pfam17380  430 EEARQREVRRLEEERAREMERVRLEEQERQQQVERLRQQEeERKRKKLELEKEKRDRKRAEEqrrKILEKELEERKQAMI 509

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....*..
gi 1958645968 1026 NEQRvefaalqealTHAMTEKEGKDQELAKLREQEAAQISELKALQQ 1072
Cdd:pfam17380  510 EEER----------KRKLLEKEMEERQKAIYEEERRREAEEERRKQQ 546
hsdR PRK11448
type I restriction enzyme EcoKI subunit R; Provisional
 1561-1678 3.19e-03

type I restriction enzyme EcoKI subunit R; Provisional


Pssm-ID: 236912 [Multi-domain]  Cd Length: 1123  Bit Score: 42.63  E-value: 3.19e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1561 ESQQEVQCLQTQLSELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQE----LREQLQDLEQLQKDNKELRSET-ERL 1635
Cdd:PRK11448   139 DPENLLHALQQEVLTLKQQLELQAREKAQSQALAEAQQQELVALEGLAAEleekQQELEAQLEQLQEKAAETSQERkQKR 218

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|...
gi 1958645968 1636 GRELQQAGLKTKEAEQACRHLTaqvrsleaqvahaDQQLRDLG 1678
Cdd:PRK11448   219 KEITDQAAKRLELSEEETRILI-------------DQQLRKAG 248
PRK06975 PRK06975
bifunctional uroporphyrinogen-III synthetase/uroporphyrin-III C-methyltransferase; Reviewed
 1534-1738 3.19e-03

bifunctional uroporphyrinogen-III synthetase/uroporphyrin-III C-methyltransferase; Reviewed


Pssm-ID: 235899 [Multi-domain]  Cd Length: 656  Bit Score: 42.40  E-value: 3.19e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1534 LNKKLTESEQASRVQQQKLKAfQAQggESQQEVQCLQTQLSELQAQLSQKEQaaehyklqmekakthydakkqQNQELRE 1613
Cdd:PRK06975   344 LNRKVDRLDQELVQRQQANDA-QTA--ELRVKTEQAQASVHQLDSQFAQLDG---------------------KLADAQS 399

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1614 QLQDLEQLQKDNKELRSETERlgRELQQagLKTKEAEQAcrHLTAQVRSLEAQVAHADQQLRDLGKFQVAT--------- 1684
Cdd:PRK06975   400 AQQALEQQYQDLSRNRDDWMI--AEVEQ--MLSSASQQL--QLTGNVQLALIALQNADARLATSDSPQAVAvrkaiaqdi 473

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1958645968 1685 DALKSrepqvKPQLDLS------------IDSLDLSLEEGTPCSVASKLPRTQPDGTSVPGEPASP 1738
Cdd:PRK06975   474 ERLKA-----APSADLTglaiklddaiakIDALPLSGEALPPHATMAAAPAAAAAAAAAAAAAGEP 534
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
929-1350 3.45e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 42.45  E-value: 3.45e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  929 PPRAGNQESDWEEEQARPLGSTQAALKAVQREAEQMGGELERLRAALMQSQGQQQEVRgqQEREVARLTQERGQAQADLA 1008
Cdd:COG4717     65 KPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLE--KLLQLLPLYQELEALEAELA 142

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1009 QEKAAKAELEMR------LQNTLNEQRVEFAALQEALTHAM------TEKEGKD--QELAKLREQEAAQISELKALQQTL 1074
Cdd:COG4717    143 ELPERLEELEERleelreLEEELEELEAELAELQEELEELLeqlslaTEEELQDlaEELEELQQRLAELEEELEEAQEEL 222

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1075 EELKkkekehptggARGEDASGDGPGSQLHTPGKTEAPGPEVEALRAEISKLERQWQQQQQQVEGLTHSLESERACRAEQ 1154
Cdd:COG4717    223 EELE----------EELEQLENELEAAALEERLKEARLLLLIAAALLALLGLGGSLLSLILTIAGVLFLVLGLLALLFLL 292

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1155 DKALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQDHSKAE-EEWKAQVARGQQEAERKSSLISSLEEEVSILNR 1233
Cdd:COG4717    293 LAREKASLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEElLELLDRIEELQELLREAEELEEELQLEELEQEI 372

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1234 QVLEKEG--ESKELKRLVVAESEKSQKLEERL-----RLLQVETASSSARAAERSSALREEVQSLREEVEKQRVVSENLR 1306
Cdd:COG4717    373 AALLAEAgvEDEEELRAALEQAEEYQELKEELeeleeQLEELLGELEELLEALDEEELEEELEELEEELEELEEELEELR 452

                          410       420       430       440
                   ....*....|....*....|....*....|....*....|....*.
gi 1958645968 1307 QELASQAERAE--ESGQELKAWQEKFFQKEQALSALQLEHTSTQAL 1350
Cdd:COG4717    453 EELAELEAELEqlEEDGELAELLQELEELKAELRELAEEWAALKLA 498
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 584-823 3.71e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 42.12  E-value: 3.71e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  584 EAREASVRERDAARQQLETLEKEKDAKLESLQQQLQASNEARDTAQTSVTQAQREKAELSQKIGELHACIEAAHQEQRQA 663
Cdd:COG3883     19 QAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARALYRS 98

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  664 QAHVTELEAQLKAEQ-QKATEREKVVQekvQLQEQLQALEETLKIVRGSLEEEKCRAADALKEQQRHATEMEAETRHLME 742
Cdd:COG3883     99 GGSVSYLDVLLGSESfSDFLDRLSALS---KIADADADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAELEA 175

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  743 QREQEQKELEQEKAERKGLEARLQQLEEAHQAETEALRHELAGATAAQHGAESEREQLLREVESWQKRVEARQQEEARYG 822
Cdd:COG3883    176 QQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAASAAGAGAAGAA 255


                   .
gi 1958645968  823 A 823
Cdd:COG3883    256 G 256
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 1373-1638 3.76e-03

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 42.42  E-value: 3.76e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1373 KRFREEIEQSKQAAGGLQAELMRAQRELG-----ELGSLRQ--KIVEQERAAQQLRAEKASYAEQLSMLKKAHGLLAEEN 1445
Cdd:pfam17380  315 RRKLEEAEKARQAEMDRQAAIYAEQERMAmererELERIRQeeRKRELERIRQEEIAMEISRMRELERLQMERQQKNERV 394

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1446 RGLGERANlGRQFLEVELDQAREKYVQELAAVRTDAE-THLAEMRQEAQSTSRELEVMTAKYESAKVKVLEERQRFQEER 1524
Cdd:pfam17380  395 RQELEAAR-KVKILEEERQRKIQQQKVEMEQIRAEQEeARQREVRRLEEERAREMERVRLEEQERQQQVERLRQQEEERK 473

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1525 QKLTAQVEELNKKLTESEQASRVQQQKLKAFQAQGGESQQEVQCLQTQLSELQAQLSQKEQaaehyklqmeKAKTHYDAK 1604
Cdd:pfam17380  474 RKKLELEKEKRDRKRAEEQRRKILEKELEERKQAMIEEERKRKLLEKEMEERQKAIYEEER----------RREAEEERR 543

                          250       260       270
                   ....*....|....*....|....*....|....
gi 1958645968 1605 KQQNQELREQLQdlEQLQKDNKElRSETERLGRE 1638
Cdd:pfam17380  544 KQQEMEERRRIQ--EQMRKATEE-RSRLEAMERE 574
PRK11281 PRK11281
mechanosensitive channel MscK;
855-1073 4.11e-03

mechanosensitive channel MscK;


Pssm-ID: 236892 [Multi-domain]  Cd Length: 1113  Bit Score: 42.21  E-value: 4.11e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  855 QTGQQQSQLAQLHACLAKALQQVQEKEARAQKLLDDL-SALREKMAATNkeVACLKALVLKAGEQQAAASHELKE----- 928
Cdd:PRK11281    74 KIDRQKEETEQLKQQLAQAPAKLRQAQAELEALKDDNdEETRETLSTLS--LRQLESRLAQTLDQLQNAQNDLAEynsql 151

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  929 ------PPRAGNQESdweEEQARplgsTQ---AALKAVQREAEQMGGELERLRAALMQSQGQQQEVRgQQEREVARLTQE 999
Cdd:PRK11281   152 vslqtqPERAQAALY---ANSQR----LQqirNLLKGGKVGGKALRPSQRVLLQAEQALLNAQNDLQ-RKSLEGNTQLQD 223

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1958645968 1000 RGQAQADLAQEKAAKAELEMR-LQNTLNEQRVEFA--ALQEALTHAMTEKEGKDQELAKlrEQEA-AQISElKALQQT 1073
Cdd:PRK11281   224 LLQKQRDYLTARIQRLEHQLQlLQEAINSKRLTLSekTVQEAQSQDEAARIQANPLVAQ--ELEInLQLSQ-RLLKAT 298
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
572-775 4.24e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 42.31  E-value: 4.24e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  572 RQDHAQQLATIVEAREASVRER-DAARQQLETLEKEK-----DAKLESLQQQLQASNEARDTAQTSVTQAQREKAELSQK 645
Cdd:COG3206    169 RREEARKALEFLEEQLPELRKElEEAEAALEEFRQKNglvdlSEEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQ 248

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  646 IGELHACIEAAHQEQ--RQAQAHVTELEAQLKAEQQKATEREKVVQekvQLQEQLQALEETLK----IVRGSLEEEKCRA 719
Cdd:COG3206    249 LGSGPDALPELLQSPviQQLRAQLAELEAELAELSARYTPNHPDVI---ALRAQIAALRAQLQqeaqRILASLEAELEAL 325

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 1958645968  720 ADALKEQQRHATEMEAETRHLMEQREQEQKELEQEKAERKGLEARLQQLEEAHQAE 775
Cdd:COG3206    326 QAREASLQAQLAQLEARLAELPELEAELRRLEREVEVARELYESLLQRLEEARLAE 381
TOPEUc smart00435
DNA Topoisomerase I (eukaryota); DNA Topoisomerase I (eukaryota), DNA topoisomerase V, Vaccina ...
 1593-1676 4.91e-03

DNA Topoisomerase I (eukaryota); DNA Topoisomerase I (eukaryota), DNA topoisomerase V, Vaccina virus topoisomerase, Variola virus topoisomerase, Shope fibroma virus topoisomeras


Pssm-ID: 214661 [Multi-domain]  Cd Length: 391  Bit Score: 41.57  E-value: 4.91e-03
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  1593 QMEKAKTHYDAKKQQNQELREQLQDLEQLQKDNKELRSETERLGRELQQAGLKTKEAEQACRHLTAQVRSLEAQVAHADQ 1672
Cdd:smart00435  278 SMEKLQEKIKALKYQLKRLKKMILLFEMISDLKRKLKSKFERDNEKLDAEVKEKKKEKKKEEKKKKQIERLEERIEKLEV 357


                    ....
gi 1958645968  1673 QLRD 1676
Cdd:smart00435  358 QATD 361
46 PHA02562
endonuclease subunit; Provisional
 494-703 5.04e-03

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 41.92  E-value: 5.04e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  494 LTAQLASLTALNATLQQQDQELTSLKEQAKKEQAQMLQTLQ----EQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQE 569
Cdd:PHA02562   179 LNQQIQTLDMKIDHIQQQIKTYNKNIEEQRKKNGENIARKQnkydELVEEAKTIKAEIEELTDELLNLVMDIEDPSAALN 258

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  570 AARQDHAQ---QLATIveAREASVRERD----AARQQLET----LEKEKDaKLESLQQQLQASNEARDTAQ---TSVTQA 635
Cdd:PHA02562   259 KLNTAAAKiksKIEQF--QKVIKMYEKGgvcpTCTQQISEgpdrITKIKD-KLKELQHSLEKLDTAIDELEeimDEFNEQ 335

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1958645968  636 QREKAELSQKIGELHACIEAAHQEQRQAQAHVTELEAQLKaeqQKATEREKVVQEKVQLQEQLQALEE 703
Cdd:PHA02562   336 SKKLLELKNKISTNKQSLITLVDKAKKVKAAIEELQAEFV---DNAEELAKLQDELDKIVKTKSELVK 400
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 952-1612 5.69e-03

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 41.75  E-value: 5.69e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  952 AALKAVQREAEQMGGELERLRAALMQSQGQQQEVRGQQEREvARLTQERGQAQADLAQEKAAkaeLEMRLQNTLNEQRVE 1031
Cdd:pfam12128  234 AGIMKIRPEFTKLQQEFNTLESAELRLSHLHFGYKSDETLI-ASRQEERQETSAELNQLLRT---LDDQWKEKRDELNGE 309

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1032 FAALQEALTHAMTEKEGKDQELA---KLREQEAAQISELKALQQTLEELKKKEKEHPTGGARGEDAsgdgpgsqlhtpgk 1108
Cdd:pfam12128  310 LSAADAAVAKDRSELEALEDQHGaflDADIETAAADQEQLPSWQSELENLEERLKALTGKHQDVTA-------------- 375

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1109 teapgpEVEALRAEISklerqwQQQQQQVEGLTHSLESERACRAEQDKALETLQGQLEEKARELGHNQAASASAQRELQA 1188
Cdd:pfam12128  376 ------KYNRRRSKIK------EQNNRDIAGIKDKLAKIREARDRQLAVAEDDLQALESELREQLEAGKLEFNEEEYRLK 443

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1189 LRAK----AQDHSKAEEEWKAQVARGQQEAERKSSLISSLEEEVSILNRQVLEKEGESKELKRlvvAESEKSQKLEERLR 1264
Cdd:pfam12128  444 SRLGelklRLNQATATPELLLQLENFDERIERAREEQEAANAEVERLQSELRQARKRRDQASE---ALRQASRRLEERQS 520

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1265 LLQVETASSSARAAERSSALREEVQSLREEVEKQRVVSENLRQELASQAERAEESGQElkawqeKFFQKEQALSALQLE- 1343
Cdd:pfam12128  521 ALDELELQLFPQAGTLLHFLRKEAPDWEQSIGKVISPELLHRTDLDPEVWDGSVGGEL------NLYGVKLDLKRIDVPe 594

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1344 -HTSTQALVSELLPAKhlcqQLQAEQAAAEKRFREEIEQSKQAAGGLQAELMRAQREL-----------GELGSLRQKIV 1411
Cdd:pfam12128  595 wAASEEELRERLDKAE----EALQSAREKQAAAEEQLVQANGELEKASREETFARTALknarldlrrlfDEKQSEKDKKN 670

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1412 EQERAAQQLRAEK-ASYAEQLSMLKKAHGLLAEENRG----LGERANLGRQFLEVELDQAREKYVQELAAVRTDAETHLA 1486
Cdd:pfam12128  671 KALAERKDSANERlNSLEAQLKQLDKKHQAWLEEQKEqkreARTEKQAYWQVVEGALDAQLALLKAAIAARRSGAKAELK 750

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1487 EMRQEAQST--------------SRELEVMTAKYESAKV---KVLE-----------ERQRFQEERQKLTAQVEELNKKL 1538
Cdd:pfam12128  751 ALETWYKRDlaslgvdpdviaklKREIRTLERKIERIAVrrqEVLRyfdwyqetwlqRRPRLATQLSNIERAISELQQQL 830

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1539 TESEQASRVQQQKL-------KAFQAQGGESQQEVQCLQTQLSELQ--AQLSQKEQAAEHYKLQMEKAK-THYDAKKQQN 1608
Cdd:pfam12128  831 ARLIADTKLRRAKLemerkasEKQQVRLSENLRGLRCEMSKLATLKedANSEQAQGSIGERLAQLEDLKlKRDYLSESVK 910


                   ....
gi 1958645968 1609 QELR 1612
Cdd:pfam12128  911 KYVE 914
Spc7 smart00787
Spc7 kinetochore protein; This domain is found in cell division proteins which are required ...
 1497-1641 6.24e-03

Spc7 kinetochore protein; This domain is found in cell division proteins which are required for kinetochore-spindle association.


Pssm-ID: 197874 [Multi-domain]  Cd Length: 312  Bit Score: 41.16  E-value: 6.24e-03
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  1497 RELEVMTAKYEsakvKVLEERQRFQEERQKLTAQVEELNKKLTESEQASRVQQQK----LKAFQAQGGESQQEVQCLQTQ 1572
Cdd:smart00787  151 ENLEGLKEDYK----LLMKELELLNSIKPKLRDRKDALEEELRQLKQLEDELEDCdpteLDRAKEKLKKLLQEIMIKVKK 226

                            90       100       110       120       130       140       150
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  1573 LSELQAQLSQKEQAAEhyklqmekakthydAKKQQNQELREQLQDLEQLQKDNKEL-RSETERLGRELQQ 1641
Cdd:smart00787  227 LEELEEELQELESKIE--------------DLTNKKSELNTEIAEAEKKLEQCRGFtFKEIEKLKEQLKL 282
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 1158-1633 6.32e-03

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 41.96  E-value: 6.32e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1158 LETLQGQLEEKARELGHNQAASASAQRELQALRAKAQDHSKAEEEWKAQVARGQQEAERKSSLisSLEEEVSILNRQVLE 1237
Cdd:TIGR00606  449 LEKKQEELKFVIKELQQLEGSSDRILELDQELRKAERELSKAEKNSLTETLKKEVKSLQNEKA--DLDRKLRKLDQEMEQ 526

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1238 KEGESKELKRLVVAESEKSQKLEE--RLRLLQVETASSSARAAERSSALREEVQSLREEVEKQRVVSENLRQELASQAER 1315
Cdd:TIGR00606  527 LNHHTTTRTQMEMLTKDKMDKDEQirKIKSRHSDELTSLLGYFPNKKQLEDWLHSKSKEINQTRDRLAKLNKELASLEQN 606

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1316 AEESGQELKAWQEKFFQKEQALsalqLEHTSTQALVSELlpakhlcqqlqaeqaaaeKRFREEIEQSKQAAGGLQAELMR 1395
Cdd:TIGR00606  607 KNHINNELESKEEQLSSYEDKL----FDVCGSQDEESDL------------------ERLKEEIEKSSKQRAMLAGATAV 664

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1396 AQRELGELGSLRQKIVEQERAAQQLRAEKASYAEQL-SMLKKAHGLLAEENRGLGERAN-----LGRQFLEVELDQAREK 1469
Cdd:TIGR00606  665 YSQFITQLTDENQSCCPVCQRVFQTEAELQEFISDLqSKLRLAPDKLKSTESELKKKEKrrdemLGLAPGRQSIIDLKEK 744

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1470 YVQELAAVRTDAETHLAEMRQEAQSTSRELEVMTAKYESAK-----VKVLEERQRFQEERQKLTAQ-------------V 1531
Cdd:TIGR00606  745 EIPELRNKLQKVNRDIQRLKNDIEEQETLLGTIMPEEESAKvcltdVTIMERFQMELKDVERKIAQqaaklqgsdldrtV 824

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1532 EELNKKLTESEQASRVQQQKLKAFQAQGGESQQEVQCLQTQLSELQAQ-------LSQKEQAAEHYKLQMEKAKTHYDAK 1604
Cdd:TIGR00606  825 QQVNQEKQEKQHELDTVVSKIELNRKLIQDQQEQIQHLKSKTNELKSEklqigtnLQRRQQFEEQLVELSTEVQSLIREI 904

                          490       500
                   ....*....|....*....|....*....
gi 1958645968 1605 KQQNQELREQLQDLEQLQKDNKELRSETE 1633
Cdd:TIGR00606  905 KDAKEQDSPLETFLEKDQQEKEELISSKE 933
COG3899 COG3899
Predicted ATPase [General function prediction only];
761-1325 6.99e-03

Predicted ATPase [General function prediction only];


Pssm-ID: 443106 [Multi-domain]  Cd Length: 1244  Bit Score: 41.77  E-value: 6.99e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  761 LEARLQQLEEAHQAETEALRHELAGATAAQHGAESEREQLLREV-----ESWQKRVEARQQEEARYGAMFQEQLMALKGE 835
Cdd:COG3899    688 LFELAHHLNRAGERDRAARLLLRAARRALARGAYAEALRYLERAlellpPDPEEEYRLALLLELAEALYLAGRFEEAEAL 767

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  836 HGKIGQEEQKEAGEIHGEGQTGQQQSQLAQLHACLAKALQQVQEKEARAQKLLDDLSALREKMAATNkevacLKALVLKA 915
Cdd:COG3899    768 LERALAARALAALAALRHGNPPASARAYANLGLLLLGDYEEAYEFGELALALAERLGDRRLEARALF-----NLGFILHW 842

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  916 GEQQAAASHELKEPPRAGNQESDWEEEQARPLGSTQAALKAVQREAEQMGGELERLRAALMQSQGQQQEVRGQQEREVAR 995
Cdd:COG3899    843 LGPLREALELLREALEAGLETGDAALALLALAAAAAAAAAAAALAAAAAAAARLLAAAAAALAAAAAAAALAAAELARLA 922

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  996 LTQERGQAQADLAQEkAAKAELEMRLQNTLNEQRVEFAALQEALTHAmtekegkDQELAKLREQEAAQISELKALQQTLE 1075
Cdd:COG3899    923 AAAAAAAALALAAAA-AAAAAAALAAAAAAAALAAALALAAAAAAAA-------AAALAAAAAAAAAAAAAAAAAALEAA 994

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1076 ELKKKEKEHPTGGARGEDASGDGPGSQLHTPGKTEAPGPEVEALRAEISKLERQWQQQQQQVEGLTHSLESERACRAEQD 1155
Cdd:COG3899    995 AAALLALLAAAAAAAAAAAALAAALLAAALAALAAAAAAAALLAAAAALALLAALAAAAAAAAAAAALAAAAALLAAAAA 1074

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1156 KALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQDHSKAEEEWKAQVARGQQEAERKSSLISSLEEEVSILNRQV 1235
Cdd:COG3899   1075 AAAAAAAAAAAAALAAALAAAALAAAAAAALALAAALAALALAAALAALALAAAARAAAALLLLAAALALALAALLLLAA 1154

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1236 LEKEGESKELKRLVVAESEKSQKLEERLRLLQVETASSSARAAERSSALREEVQSLREEVEKQRVVSENLRQELASQAER 1315
Cdd:COG3899   1155 LLLALALLLLALAALALAAALAALAAALLAAAAAAAAAAALLAALLALAARLAALLALALLALEAAALLLLLLLAALALA 1234

                          570
                   ....*....|
gi 1958645968 1316 AEESGQELKA 1325
Cdd:COG3899   1235 AALLALRLLA 1244
COG4372 COG4372
Uncharacterized protein, contains DUF3084 domain [Function unknown];
1504-1682 7.11e-03

Uncharacterized protein, contains DUF3084 domain [Function unknown];


Pssm-ID: 443500 [Multi-domain]  Cd Length: 370  Bit Score: 41.04  E-value: 7.11e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1504 AKYESAKVKVLEERQRFQEERQKLTAQVEELNKKLTESEQASRVQQQKLKAFQAQGGESQQEVQCLQTQLSELQAQLSQK 1583
Cdd:COG4372      6 EKVGKARLSLFGLRPKTGILIAALSEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEEL 85

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1584 EQAAEHYKLQMEKAKTHYDAKKQQNQELREQLqdlEQLQKDNKELRSETERLGRELQQAGLKTKEAEQACRHLTAQVRSL 1663
Cdd:COG4372     86 NEQLQAAQAELAQAQEELESLQEEAEELQEEL---EELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESL 162

                          170
                   ....*....|....*....
gi 1958645968 1664 EAQVAHADQQLRDLGKFQV 1682
Cdd:COG4372    163 QEELAALEQELQALSEAEA 181
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 267-482 7.14e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 40.90  E-value: 7.14e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  267 AASPQEPSELEELRGKNESLTVRLHETLKQCQNLKTEKNQMDRKISQLSEENGDLSFKVREFANHLQQLQGAFNDLIEEH 346
Cdd:COG4942     13 LAAAAQADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEI 92

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  347 SKASQEWAEKQAHLESELSTAL--------------QDKKCLEEKSEILQEKISQLEDRAAQLQGspapEKGEVLGDALQ 412
Cdd:COG4942     93 AELRAELEAQKEELAELLRALYrlgrqpplalllspEDFLDAVRRLQYLKYLAPARREQAEELRA----DLAELAALRAE 168

                          170       180       190       200       210       220       230
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  413 LDTLKQEAAKLATDNTELQARVETLECERGKQEAQLLAERGHFEEEKRQLASLVADLQSSVSNLSQAKEE 482
Cdd:COG4942    169 LEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAA 238
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 262-763 7.42e-03

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 41.25  E-value: 7.42e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  262 LNEKQAASPQEPSELEELRGKNESLTVRLHETLKQCQNLKTEKNQMDRKISQLSEENGDLSFKVREFA------------ 329
Cdd:pfam05483  108 LQENRKIIEAQRKAIQELQFENEKVSLKLEEEIQENKDLIKENNATRHLCNLLKETCARSAEKTKKYEyereetrqvymd 187

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  330 --NHLQQLQGAFNDL--------IEEHSKASQEWaEKQAHLESELSTALQDKkclEEKSEIL----QEKISQLEDRAAQL 395
Cdd:pfam05483  188 lnNNIEKMILAFEELrvqaenarLEMHFKLKEDH-EKIQHLEEEYKKEINDK---EKQVSLLliqiTEKENKMKDLTFLL 263

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  396 QGSPAPEKGEVLGDALQLDTLKQEAAKLATDNTELQARVETLECERGKQEA-------------QLLAERGHFEEEKRQL 462
Cdd:pfam05483  264 EESRDKANQLEEKTKLQDENLKELIEKKDHLTKELEDIKMSLQRSMSTQKAleedlqiatkticQLTEEKEAQMEELNKA 343

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  463 ASLVADLQSSVSNLSQAKEELQQASQAQGAQLTAQLASLTALNATLQQQDQELTSLKEQAKKEQAQMLQTLQEQEQAAQG 542
Cdd:pfam05483  344 KAAHSFVVTEFEATTCSLEELLRTEQQRLEKNEDQLKIITMELQKKSSELEEMTKFKNNKEVELEELKKILAEDEKLLDE 423

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  543 lRQQVEQLSSSLKLKEQQLEEAAKEQEAARQDHAQQLATIVEAREASVRERDAARQQLETlEKEKDAKLESLQQQLQASN 622
Cdd:pfam05483  424 -KKQFEKIAEELKGKEQELIFLLQAREKEIHDLEIQLTAIKTSEEHYLKEVEDLKTELEK-EKLKNIELTAHCDKLLLEN 501

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  623 EARDTAQTSVTQAQREKAElsqkigelhACIEAAHQEQRQAQAHVTELEAQLKAEQQKATEREKVVQEKVQLQEQLQALE 702
Cdd:pfam05483  502 KELTQEASDMTLELKKHQE---------DIINCKKQEERMLKQIENLEEKEMNLRDELESVREEFIQKGDEVKCKLDKSE 572

                          490       500       510       520       530       540
                   ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 1958645968  703 ETLKIVRGSLEEEKCRAADALKEQQRHATEMEAETRHLMEQREQEQKELEQEKAERKGLEA 763
Cdd:pfam05483  573 ENARSIEYEVLKKEKQMKILENKCNNLKKQIENKNKNIEELHQENKALKKKGSAENKQLNA 633
NFACT_N pfam05833
NFACT N-terminal and middle domains; This family contains the N-terminal and middle domains of ...
 1517-1647 8.20e-03

NFACT N-terminal and middle domains; This family contains the N-terminal and middle domains of NFACT (NEMF, FbpA, Caliban, and Tae2) proteins from eukaryotes, archaea and bacteria. Many members of this family act in ribosome quality control (RQC), including RqcH, which are involved in the addition of a poly-Ala tail to defective translated proteins to tag them for degradation. This process is analogous to the ssrA/tmRNA bacterial system. However, some other NFACT family members, such as bacterial proteins FbpA in Listeria or PavA in Streptococcus, are exported (despite lack of a classical signal peptide) and behave as fibronectin-binding adhesins associated with virulence.


Pssm-ID: 428644 [Multi-domain]  Cd Length: 451  Bit Score: 41.07  E-value: 8.20e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1517 RQRFQEERQKLTAQVEELNKKLTESEQASRVQQQK--LKAF--QAQGGESQQEVQCLQTQLSE----LQAQLSQKEQAAE 1588
Cdd:pfam05833  301 EKVVQNELEKLEKKLKKLEKELEEAENADEYRLYGelLTANlyQIKKGMKEVELPNYYDEGEPvtipLDPAKSPSENAQK 380

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 1958645968 1589 HYKLQmEKAKTHYDAKKQQNQELREQLQDLEQL--QKDNKELRSETERLGRELQQAG-LKTK 1647
Cdd:pfam05833  381 YFKKY-QKLKRAVEAVKEQIEETKEEIEYLESVetQLENAESLDDLEEIREELIEQGyLKKK 441
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 508-677 9.19e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 39.91  E-value: 9.19e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  508 LQQQDQELTSLKEQAKKEQAQmlqtLQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEAARQDHAQQLATIVEARe 587
Cdd:COG1579     12 LQELDSELDRLEHRLKELPAE----LAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNVR- 86

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  588 aSVRERDAARQQLETLEKEKdaklESLQQQLQASNEARDTAQTSVTQAQREKAELSQKIGELHACIEAAHQEQRQAQAHV 667
Cdd:COG1579     87 -NNKEYEALQKEIESLKRRI----SDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEEL 161

                          170
                   ....*....|
gi 1958645968  668 TELEAQLKAE 677
Cdd:COG1579    162 EAEREELAAK 171
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 1151-1298 9.44e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 39.91  E-value: 9.44e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1151 RAEQDKALETLQGQLEEKARELGHNQAASASAQRELQALRAKAQDHSKAEEEWKAQV--ARGQQEAERKSSLISSLEEEV 1228
Cdd:COG1579     26 LKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLgnVRNNKEYEALQKEIESLKRRI 105

                           90       100       110       120       130       140       150
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1229 SILNRQVLEKEGESKELKRLVVAESEKSQKLEERLRLLQVETASSSARAAERSSALREEVQSLREEVEKQ 1298
Cdd:COG1579    106 SDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAELEAELEELEAEREELAAKIPPE 175
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1390-1588 9.65e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 41.16  E-value: 9.65e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1390 QAELMRAQREL-GELGSLRQKIVEQERAAQQLRA---------EKASYAEQLSMLKKAHGLLAEENRGLGERANLGRQFL 1459
Cdd:COG3206    170 REEARKALEFLeEQLPELRKELEEAEAALEEFRQknglvdlseEAKLLLQQLSELESQLAEARAELAEAEARLAALRAQL 249

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968 1460 EVELDQARE----KYVQELAAVRTDAETHLAEMRQEAQSTSRELEVMTAKYESAKVKVLEERQRF----QEERQKLTAQV 1531
Cdd:COG3206    250 GSGPDALPEllqsPVIQQLRAQLAELEAELAELSARYTPNHPDVIALRAQIAALRAQLQQEAQRIlaslEAELEALQARE 329

                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 1958645968 1532 EELNKKLTESEQasrvQQQKLKAFQAQGGESQQEVQCLQTQLSELQAQLSQKEQAAE 1588
Cdd:COG3206    330 ASLQAQLAQLEA----RLAELPELEAELRRLEREVEVARELYESLLQRLEEARLAEA 382
mukB PRK04863
chromosome partition protein MukB;
430-833 9.71e-03

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 41.10  E-value: 9.71e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  430 LQARVETLECERGKQEAQ--LLAERGHFEEEKRQLASLVADLQSSVSNLSQAKEELQQASQAQGAQltaqlASLTALNAT 507
Cdd:PRK04863   289 LELRRELYTSRRQLAAEQyrLVEMARELAELNEAESDLEQDYQAASDHLNLVQTALRQQEKIERYQ-----ADLEELEER 363

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  508 LQQQdqeltslkEQAKKEQAQMLQTLQEQEQAAQglrQQVEQLSSSL-----KLKEQQLEEAAKEQEAARQDHAQQLATI 582
Cdd:PRK04863   364 LEEQ--------NEVVEEADEQQEENEARAEAAE---EEVDELKSQLadyqqALDVQQTRAIQYQQAVQALERAKQLCGL 432

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  583 VEAREASVRERDAarqQLETLEKEKDAKLESLQQQLQASNEARD------------TAQTSVTQAQREKAELsqkigeLH 650
Cdd:PRK04863   433 PDLTADNAEDWLE---EFQAKEQEATEELLSLEQKLSVAQAAHSqfeqayqlvrkiAGEVSRSEAWDVAREL------LR 503

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  651 ACIEAAHQEQR--QAQAHVTELEAQLkAEQQKATEREKVVQEKVQLQEQLQALEETLKIVRGSLEEEkcraadaLKEQQR 728
Cdd:PRK04863   504 RLREQRHLAEQlqQLRMRLSELEQRL-RQQQRAERLLAEFCKRLGKNLDDEDELEQLQEELEARLES-------LSESVS 575

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1958645968  729 HATEMEAETRHLMEQREQEQKELEQEKAERKGLEARLQQLEEaHQAETEALRHELAGATAAQHGAESEREQLLREVESWQ 808
Cdd:PRK04863   576 EARERRMALRQQLEQLQARIQRLAARAPAWLAAQDALARLRE-QSGEEFEDSQDVTEYMQQLLERERELTVERDELAARK 654

                          410       420
                   ....*....|....*....|....*
gi 1958645968  809 KRVEARQQEEARYGAMFQEQLMALK 833
Cdd:PRK04863   655 QALDEEIERLSQPGGSEDPRLNALA 679
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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