|
Name |
Accession |
Description |
Interval |
E-value |
| LRR_RI |
cd00116 |
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ... |
861-1160 |
5.25e-68 |
|
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).
:
Pssm-ID: 238064 [Multi-domain] Cd Length: 319 Bit Score: 231.48 E-value: 5.25e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2025748883 861 LTRYLKRLKLGSLRAGRLLELLHCaheTQEPGIWEHVVHQlpGHLSFLGTRLTPP--DVHVLGRALETASqdfslDLRQT 938
Cdd:cd00116 1 LQLSLKGELLKTERATELLPKLLC---LQVLRLEGNTLGE--EAAKALASALRPQpsLKELCLSLNETGR-----IPRGL 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2025748883 939 GIEPSGLGNLVGLSCVTSFRAALS-DTMVLWESLRH---QGEPQLLQAAEEKfTLEPFKAKSPKDV-EDLDSLVQTQRLR 1013
Cdd:cd00116 71 QSLLQGLTKGCGLQELDLSDNALGpDGCGVLESLLRsssLQELKLNNNGLGD-RGLRLLAKGLKDLpPALEKLVLGRNRL 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2025748883 1014 N--PSEDAALDLPAIRDLKKLEFAL-----------------------DSLSENKIGDEGVSRLAATFTQLKVLETLNLS 1068
Cdd:cd00116 150 EgaSCEALAKALRANRDLKELNLANngigdagiralaeglkancnlevLDLNNNGLTDEGASALAETLASLKSLEVLNLG 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2025748883 1069 QNSITDVGACKLAEALPALAKSLLRLsSLYNNCICDAGARSLAQVLPDMVSLRVMDVQFNKFTAAGAQQLASSLqKCPQV 1148
Cdd:cd00116 230 DNNLTDAGAAALASALLSPNISLLTL-SLSCNDITDDGAKDLAEVLAEKESLLELDLRGNKFGEEGAQLLAESL-LEPGN 307
|
330
....*....|..
gi 2025748883 1149 ETLAMWTPTIPF 1160
Cdd:cd00116 308 ELESLWVKDDSF 319
|
|
| NACHT |
pfam05729 |
NACHT domain; This NTPase domain is found in apoptosis proteins as well as those involved in ... |
489-660 |
5.11e-49 |
|
NACHT domain; This NTPase domain is found in apoptosis proteins as well as those involved in MHC transcription activation. This family is closely related to pfam00931.
:
Pssm-ID: 428606 [Multi-domain] Cd Length: 166 Bit Score: 171.33 E-value: 5.11e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2025748883 489 QVVAVLGKAGQGKSHWARTVSQAWARGQLPQY-DFVFYVPCHCLDHPGDTYHLQDLLCPPSLQPLVMDDEVLGHIVRQPD 567
Cdd:pfam05729 1 RTVILQGEAGSGKTTLLQKLALLWAQGKLPQGfDFVFFLPCRELSRSGNARSLADLLFSQWPEPAAPVSEVWAVILELPE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2025748883 568 RVLLILDAFEELEAQDGLLHGPCGPLppepcsfrGLLAGLFQRKLLRGCTLLLTARPRGR--LTQSLSKADaIFEVPSFS 645
Cdd:pfam05729 81 RLLLILDGLDELVSDLGQLDGPCPVL--------TLLSSLLRKKLLPGASLLLTVRPDALrdLRRGLEEPR-YLEVRGFS 151
|
170
....*....|....*
gi 2025748883 646 TRQAQTYMRHYFENS 660
Cdd:pfam05729 152 ESDRKQYVRKYFSDE 166
|
|
| NLRC4_HD2 super family |
cl39284 |
NLRC4 helical domain HD2; This entry represents a helical domain found in the NLRC4 protein ... |
788-890 |
1.17e-07 |
|
NLRC4 helical domain HD2; This entry represents a helical domain found in the NLRC4 protein and NOD2 protein.
The actual alignment was detected with superfamily member pfam17776:
Pssm-ID: 465499 [Multi-domain] Cd Length: 122 Bit Score: 51.52 E-value: 1.17e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2025748883 788 LQCFLGAVWLAQCNEIRDKELPQYLaLTPRKKRPYDNWLEGVP-----------RFLTGLVFQPRAHCLGALMEPAVADR 856
Cdd:pfam17776 4 FQEFFAALFYVLSFKEEKSNPLKEF-FGLRKRESLKSLLDKALksknghldlflRFLFGLLNEENQRLLEGLLGCKLSSE 82
|
90 100 110
....*....|....*....|....*....|....
gi 2025748883 857 KRKVLTRYLKRLKLGSLRAGRLLELLHCAHETQE 890
Cdd:pfam17776 83 IKQELLQWIKSLIQKELSSERFLNLFHCLYELQD 116
|
|
| PHA03377 super family |
cl31823 |
EBNA-3C; Provisional |
197-425 |
1.14e-05 |
|
EBNA-3C; Provisional
The actual alignment was detected with superfamily member PHA03377:
Pssm-ID: 177614 [Multi-domain] Cd Length: 1000 Bit Score: 49.67 E-value: 1.14e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2025748883 197 IERIETEEGFSESME---VPVEAGERSQKRRS----PEEHPMDPKHRKLAEPSMVPMLTGSFLMGPASISTMPYLPPALS 269
Cdd:PHA03377 517 VETTEEEESVTQPAKphrKVQDGFQRSGRRQKratpPKVSPSDRGPPKASPPVMAPPSTGPRVMATPSTGPRDMAPPSTG 596
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2025748883 270 NQEPVSCHIHLEGATQTSVPPSRSSPNCLDLTIGHI----QLLPT----LPQGLWQIQgAGTGLPSVliyhgEMPQVNHV 341
Cdd:PHA03377 597 PRQQAKCKDGPPASGPHEKQPPSSAPRDMAPSVVRMflreRLLEQstgpKPKSFWEMR-AGRDGSGI-----QQEPSSRR 670
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2025748883 342 IPSGSPTvsslpksPDRPCstspFAPSVADLPSMPepaltsrvneaedTTSPSPCQEGPESPIKlPKWPASverfqHSLK 421
Cdd:PHA03377 671 QPATQST-------PPRPS----WLPSVFVLPSVD-------------AGRAQPSEESHLSSMS-PTQPIS-----HEEQ 720
|
....
gi 2025748883 422 DKYQ 425
Cdd:PHA03377 721 PRYE 724
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| LRR_RI |
cd00116 |
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ... |
861-1160 |
5.25e-68 |
|
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).
Pssm-ID: 238064 [Multi-domain] Cd Length: 319 Bit Score: 231.48 E-value: 5.25e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2025748883 861 LTRYLKRLKLGSLRAGRLLELLHCaheTQEPGIWEHVVHQlpGHLSFLGTRLTPP--DVHVLGRALETASqdfslDLRQT 938
Cdd:cd00116 1 LQLSLKGELLKTERATELLPKLLC---LQVLRLEGNTLGE--EAAKALASALRPQpsLKELCLSLNETGR-----IPRGL 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2025748883 939 GIEPSGLGNLVGLSCVTSFRAALS-DTMVLWESLRH---QGEPQLLQAAEEKfTLEPFKAKSPKDV-EDLDSLVQTQRLR 1013
Cdd:cd00116 71 QSLLQGLTKGCGLQELDLSDNALGpDGCGVLESLLRsssLQELKLNNNGLGD-RGLRLLAKGLKDLpPALEKLVLGRNRL 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2025748883 1014 N--PSEDAALDLPAIRDLKKLEFAL-----------------------DSLSENKIGDEGVSRLAATFTQLKVLETLNLS 1068
Cdd:cd00116 150 EgaSCEALAKALRANRDLKELNLANngigdagiralaeglkancnlevLDLNNNGLTDEGASALAETLASLKSLEVLNLG 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2025748883 1069 QNSITDVGACKLAEALPALAKSLLRLsSLYNNCICDAGARSLAQVLPDMVSLRVMDVQFNKFTAAGAQQLASSLqKCPQV 1148
Cdd:cd00116 230 DNNLTDAGAAALASALLSPNISLLTL-SLSCNDITDDGAKDLAEVLAEKESLLELDLRGNKFGEEGAQLLAESL-LEPGN 307
|
330
....*....|..
gi 2025748883 1149 ETLAMWTPTIPF 1160
Cdd:cd00116 308 ELESLWVKDDSF 319
|
|
| NACHT |
pfam05729 |
NACHT domain; This NTPase domain is found in apoptosis proteins as well as those involved in ... |
489-660 |
5.11e-49 |
|
NACHT domain; This NTPase domain is found in apoptosis proteins as well as those involved in MHC transcription activation. This family is closely related to pfam00931.
Pssm-ID: 428606 [Multi-domain] Cd Length: 166 Bit Score: 171.33 E-value: 5.11e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2025748883 489 QVVAVLGKAGQGKSHWARTVSQAWARGQLPQY-DFVFYVPCHCLDHPGDTYHLQDLLCPPSLQPLVMDDEVLGHIVRQPD 567
Cdd:pfam05729 1 RTVILQGEAGSGKTTLLQKLALLWAQGKLPQGfDFVFFLPCRELSRSGNARSLADLLFSQWPEPAAPVSEVWAVILELPE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2025748883 568 RVLLILDAFEELEAQDGLLHGPCGPLppepcsfrGLLAGLFQRKLLRGCTLLLTARPRGR--LTQSLSKADaIFEVPSFS 645
Cdd:pfam05729 81 RLLLILDGLDELVSDLGQLDGPCPVL--------TLLSSLLRKKLLPGASLLLTVRPDALrdLRRGLEEPR-YLEVRGFS 151
|
170
....*....|....*
gi 2025748883 646 TRQAQTYMRHYFENS 660
Cdd:pfam05729 152 ESDRKQYVRKYFSDE 166
|
|
| RNA1 |
COG5238 |
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ... |
1039-1173 |
3.01e-16 |
|
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];
Pssm-ID: 444072 [Multi-domain] Cd Length: 434 Bit Score: 82.53 E-value: 3.01e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2025748883 1039 LSENKIGDEGVSRLAATFTQLKVLETLNLSQNSITDVGACKLAEALPALaKSLLRLsSLYNNCICDAGARSLAQVLPDMV 1118
Cdd:COG5238 299 LSVNRIGDEGAIALAEGLQGNKTLHTLNLAYNGIGAQGAIALAKALQEN-TTLHSL-DLSDNQIGDEGAIALAKYLEGNT 376
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*
gi 2025748883 1119 SLRVMDVQFNKFTAAGAQQLASSLQKcPQVETLAMWTPTIPFGVQEHLQQLDSRI 1173
Cdd:COG5238 377 TLRELNLGKNNIGKQGAEALIDALQT-NRLHTLILDGNLIGAEAQQRLEQLLERI 430
|
|
| NLRC4_HD2 |
pfam17776 |
NLRC4 helical domain HD2; This entry represents a helical domain found in the NLRC4 protein ... |
788-890 |
1.17e-07 |
|
NLRC4 helical domain HD2; This entry represents a helical domain found in the NLRC4 protein and NOD2 protein.
Pssm-ID: 465499 [Multi-domain] Cd Length: 122 Bit Score: 51.52 E-value: 1.17e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2025748883 788 LQCFLGAVWLAQCNEIRDKELPQYLaLTPRKKRPYDNWLEGVP-----------RFLTGLVFQPRAHCLGALMEPAVADR 856
Cdd:pfam17776 4 FQEFFAALFYVLSFKEEKSNPLKEF-FGLRKRESLKSLLDKALksknghldlflRFLFGLLNEENQRLLEGLLGCKLSSE 82
|
90 100 110
....*....|....*....|....*....|....
gi 2025748883 857 KRKVLTRYLKRLKLGSLRAGRLLELLHCAHETQE 890
Cdd:pfam17776 83 IKQELLQWIKSLIQKELSSERFLNLFHCLYELQD 116
|
|
| PHA03377 |
PHA03377 |
EBNA-3C; Provisional |
197-425 |
1.14e-05 |
|
EBNA-3C; Provisional
Pssm-ID: 177614 [Multi-domain] Cd Length: 1000 Bit Score: 49.67 E-value: 1.14e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2025748883 197 IERIETEEGFSESME---VPVEAGERSQKRRS----PEEHPMDPKHRKLAEPSMVPMLTGSFLMGPASISTMPYLPPALS 269
Cdd:PHA03377 517 VETTEEEESVTQPAKphrKVQDGFQRSGRRQKratpPKVSPSDRGPPKASPPVMAPPSTGPRVMATPSTGPRDMAPPSTG 596
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2025748883 270 NQEPVSCHIHLEGATQTSVPPSRSSPNCLDLTIGHI----QLLPT----LPQGLWQIQgAGTGLPSVliyhgEMPQVNHV 341
Cdd:PHA03377 597 PRQQAKCKDGPPASGPHEKQPPSSAPRDMAPSVVRMflreRLLEQstgpKPKSFWEMR-AGRDGSGI-----QQEPSSRR 670
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2025748883 342 IPSGSPTvsslpksPDRPCstspFAPSVADLPSMPepaltsrvneaedTTSPSPCQEGPESPIKlPKWPASverfqHSLK 421
Cdd:PHA03377 671 QPATQST-------PPRPS----WLPSVFVLPSVD-------------AGRAQPSEESHLSSMS-PTQPIS-----HEEQ 720
|
....
gi 2025748883 422 DKYQ 425
Cdd:PHA03377 721 PRYE 724
|
|
| Atrophin-1 |
pfam03154 |
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ... |
220-506 |
3.21e-05 |
|
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.
Pssm-ID: 460830 [Multi-domain] Cd Length: 991 Bit Score: 48.22 E-value: 3.21e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2025748883 220 SQKRRSPEEHPMDPK-----HRKLAEPSMVPMLTG-------SFLMGPASISTMPYLPP--------ALSNQEPVSCHih 279
Cdd:pfam03154 334 LQSQQPPREQPLPPAplsmpHIKPPPTTPIPQLPNpqshkhpPHLSGPSPFQMNSNLPPppalkplsSLSTHHPPSAH-- 411
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2025748883 280 legatqtsVPPSRSSPNCLDLtighiQLLPTLPQGLWQIQG---AGTGLPSVLIYHGEMPQ----VNHVIPSGSPTVSSl 352
Cdd:pfam03154 412 --------PPPLQLMPQSQQL-----PPPPAQPPVLTQSQSlppPAASHPPTSGLHQVPSQspfpQHPFVPGGPPPITP- 477
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2025748883 353 PKSPdrPCSTSPFAP------SVADLPSMPEPALTSRV-----------NEAEDTTSPSPCQEGPESP---IKLPKWPAS 412
Cdd:pfam03154 478 PSGP--PTSTSSAMPgiqppsSASVSSSGPVPAAVSCPlppvqikeealDEAEEPESPPPPPRSPSPEptvVNTPSHASQ 555
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2025748883 413 VERFQHSLKDKYQ--VEPENLSVPMVAVELVRARLERGSNKSQERELATPDWTERQLARGGldqvlqavvDRRRPRETQV 490
Cdd:pfam03154 556 SARFYKHLDRGYNscARTDLYFMPLAGSKLAKKREEALEKAKREAEQKAREEKEREKEKEK---------ERERERERER 626
|
330
....*....|....*.
gi 2025748883 491 VAVLGKAGQGKSHWAR 506
Cdd:pfam03154 627 EAERAAKASSSSHEGR 642
|
|
| LRR_RI |
smart00368 |
Leucine rich repeat, ribonuclease inhibitor type; |
1089-1116 |
1.54e-03 |
|
Leucine rich repeat, ribonuclease inhibitor type;
Pssm-ID: 197686 [Multi-domain] Cd Length: 28 Bit Score: 37.00 E-value: 1.54e-03
10 20
....*....|....*....|....*...
gi 2025748883 1089 KSLLRLSsLYNNCICDAGARSLAQVLPD 1116
Cdd:smart00368 2 PSLRELD-LSNNKLGDEGARALAEALKD 28
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| LRR_RI |
cd00116 |
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ... |
861-1160 |
5.25e-68 |
|
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).
Pssm-ID: 238064 [Multi-domain] Cd Length: 319 Bit Score: 231.48 E-value: 5.25e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2025748883 861 LTRYLKRLKLGSLRAGRLLELLHCaheTQEPGIWEHVVHQlpGHLSFLGTRLTPP--DVHVLGRALETASqdfslDLRQT 938
Cdd:cd00116 1 LQLSLKGELLKTERATELLPKLLC---LQVLRLEGNTLGE--EAAKALASALRPQpsLKELCLSLNETGR-----IPRGL 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2025748883 939 GIEPSGLGNLVGLSCVTSFRAALS-DTMVLWESLRH---QGEPQLLQAAEEKfTLEPFKAKSPKDV-EDLDSLVQTQRLR 1013
Cdd:cd00116 71 QSLLQGLTKGCGLQELDLSDNALGpDGCGVLESLLRsssLQELKLNNNGLGD-RGLRLLAKGLKDLpPALEKLVLGRNRL 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2025748883 1014 N--PSEDAALDLPAIRDLKKLEFAL-----------------------DSLSENKIGDEGVSRLAATFTQLKVLETLNLS 1068
Cdd:cd00116 150 EgaSCEALAKALRANRDLKELNLANngigdagiralaeglkancnlevLDLNNNGLTDEGASALAETLASLKSLEVLNLG 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2025748883 1069 QNSITDVGACKLAEALPALAKSLLRLsSLYNNCICDAGARSLAQVLPDMVSLRVMDVQFNKFTAAGAQQLASSLqKCPQV 1148
Cdd:cd00116 230 DNNLTDAGAAALASALLSPNISLLTL-SLSCNDITDDGAKDLAEVLAEKESLLELDLRGNKFGEEGAQLLAESL-LEPGN 307
|
330
....*....|..
gi 2025748883 1149 ETLAMWTPTIPF 1160
Cdd:cd00116 308 ELESLWVKDDSF 319
|
|
| NACHT |
pfam05729 |
NACHT domain; This NTPase domain is found in apoptosis proteins as well as those involved in ... |
489-660 |
5.11e-49 |
|
NACHT domain; This NTPase domain is found in apoptosis proteins as well as those involved in MHC transcription activation. This family is closely related to pfam00931.
Pssm-ID: 428606 [Multi-domain] Cd Length: 166 Bit Score: 171.33 E-value: 5.11e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2025748883 489 QVVAVLGKAGQGKSHWARTVSQAWARGQLPQY-DFVFYVPCHCLDHPGDTYHLQDLLCPPSLQPLVMDDEVLGHIVRQPD 567
Cdd:pfam05729 1 RTVILQGEAGSGKTTLLQKLALLWAQGKLPQGfDFVFFLPCRELSRSGNARSLADLLFSQWPEPAAPVSEVWAVILELPE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2025748883 568 RVLLILDAFEELEAQDGLLHGPCGPLppepcsfrGLLAGLFQRKLLRGCTLLLTARPRGR--LTQSLSKADaIFEVPSFS 645
Cdd:pfam05729 81 RLLLILDGLDELVSDLGQLDGPCPVL--------TLLSSLLRKKLLPGASLLLTVRPDALrdLRRGLEEPR-YLEVRGFS 151
|
170
....*....|....*
gi 2025748883 646 TRQAQTYMRHYFENS 660
Cdd:pfam05729 152 ESDRKQYVRKYFSDE 166
|
|
| RNA1 |
COG5238 |
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ... |
1039-1173 |
3.01e-16 |
|
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];
Pssm-ID: 444072 [Multi-domain] Cd Length: 434 Bit Score: 82.53 E-value: 3.01e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2025748883 1039 LSENKIGDEGVSRLAATFTQLKVLETLNLSQNSITDVGACKLAEALPALaKSLLRLsSLYNNCICDAGARSLAQVLPDMV 1118
Cdd:COG5238 299 LSVNRIGDEGAIALAEGLQGNKTLHTLNLAYNGIGAQGAIALAKALQEN-TTLHSL-DLSDNQIGDEGAIALAKYLEGNT 376
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*
gi 2025748883 1119 SLRVMDVQFNKFTAAGAQQLASSLQKcPQVETLAMWTPTIPFGVQEHLQQLDSRI 1173
Cdd:COG5238 377 TLRELNLGKNNIGKQGAEALIDALQT-NRLHTLILDGNLIGAEAQQRLEQLLERI 430
|
|
| RNA1 |
COG5238 |
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ... |
1039-1151 |
6.43e-15 |
|
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];
Pssm-ID: 444072 [Multi-domain] Cd Length: 434 Bit Score: 78.68 E-value: 6.43e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2025748883 1039 LSENKIGDEGVSRLAATFTQLKVLETLNLSQNSITDVGACKLAEALpALAKSLLRLSSLYNNcICDAGARSLAQVLPDMV 1118
Cdd:COG5238 271 LSGNQIGAEGAIALAKALQGNTTLTSLDLSVNRIGDEGAIALAEGL-QGNKTLHTLNLAYNG-IGAQGAIALAKALQENT 348
|
90 100 110
....*....|....*....|....*....|...
gi 2025748883 1119 SLRVMDVQFNKFTAAGAQQLASSLQKCPQVETL 1151
Cdd:COG5238 349 TLHSLDLSDNQIGDEGAIALAKYLEGNTTLREL 381
|
|
| RNA1 |
COG5238 |
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ... |
1039-1168 |
1.63e-14 |
|
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];
Pssm-ID: 444072 [Multi-domain] Cd Length: 434 Bit Score: 77.14 E-value: 1.63e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2025748883 1039 LSENKIGDEGVSRLAATFTQLKVLETLNLSQNSITDVGACKLAEALPALAKslLRLSSLYNNCICDAGARSLAQVLPDMV 1118
Cdd:COG5238 187 LGCNQIGDEGIEELAEALTQNTTVTTLWLKRNPIGDEGAEILAEALKGNKS--LTTLDLSNNQIGDEGVIALAEALKNNT 264
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....
gi 2025748883 1119 SLRVMDVQFNKFTAAGAQQLASSLQKCPQVETLAMWTPTIPF----GVQEHLQQ 1168
Cdd:COG5238 265 TVETLYLSGNQIGAEGAIALAKALQGNTTLTSLDLSVNRIGDegaiALAEGLQG 318
|
|
| RNA1 |
COG5238 |
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ... |
1036-1151 |
2.37e-14 |
|
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];
Pssm-ID: 444072 [Multi-domain] Cd Length: 434 Bit Score: 76.75 E-value: 2.37e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2025748883 1036 LDsLSENKIGDEGVSRLAATFTQLKVLETLNLSQNSITDVGACKLAEALpALAKSLLRLSSLYNNcICDAGARSLAQVLP 1115
Cdd:COG5238 241 LD-LSNNQIGDEGVIALAEALKNNTTVETLYLSGNQIGAEGAIALAKAL-QGNTTLTSLDLSVNR-IGDEGAIALAEGLQ 317
|
90 100 110
....*....|....*....|....*....|....*.
gi 2025748883 1116 DMVSLRVMDVQFNKFTAAGAQQLASSLQKCPQVETL 1151
Cdd:COG5238 318 GNKTLHTLNLAYNGIGAQGAIALAKALQENTTLHSL 353
|
|
| RNA1 |
COG5238 |
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ... |
1039-1151 |
2.12e-13 |
|
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];
Pssm-ID: 444072 [Multi-domain] Cd Length: 434 Bit Score: 73.67 E-value: 2.12e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2025748883 1039 LSENKIGDEGVSRLAATFTQLKVLETLNLSQNSITDVGACKLAEALpALAKSLLRLsSLYNNCICDAGARSLAQVLPDMV 1118
Cdd:COG5238 215 LKRNPIGDEGAEILAEALKGNKSLTTLDLSNNQIGDEGVIALAEAL-KNNTTVETL-YLSGNQIGAEGAIALAKALQGNT 292
|
90 100 110
....*....|....*....|....*....|...
gi 2025748883 1119 SLRVMDVQFNKFTAAGAQQLASSLQKCPQVETL 1151
Cdd:COG5238 293 TLTSLDLSVNRIGDEGAIALAEGLQGNKTLHTL 325
|
|
| NACHT |
COG5635 |
Predicted NTPase, NACHT family domain [Signal transduction mechanisms]; |
404-1114 |
6.78e-09 |
|
Predicted NTPase, NACHT family domain [Signal transduction mechanisms];
Pssm-ID: 444362 [Multi-domain] Cd Length: 935 Bit Score: 60.20 E-value: 6.78e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2025748883 404 IKLPKWPASVERFQHSLKDKYQVEPENLSVPMVAVELVRARLERGSNKSQERELATPDWTERQLARGGLDQVLQAVVDRR 483
Cdd:COG5635 88 ESLLLLLLLLLLLAEALLALLELAALLKAVLLSLSGGSDLVLLLSESDLLLALLILLLDADGLLVSLDDLYVPLNLLERI 167
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2025748883 484 RPRET--------QVVAVLGKAGQGKSHWAR-TVSQAWARGQLPQYDFVFYVPCHclDHPGDtYHLQDLLCPPSLQPLVM 554
Cdd:COG5635 168 ESLKRlelleakkKRLLILGEPGSGKTTLLRyLALELAERYLDAEDPIPILIELR--DLAEE-ASLEDLLAEALEKRGGE 244
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2025748883 555 DDEVLGHIVRQpDRVLLILDAFEELEAQDGLLHgpcgplppepcsFRGLLAGLFQRklLRGCTLLLTARPRGRLTQSLSK 634
Cdd:COG5635 245 PEDALERLLRN-GRLLLLLDGLDEVPDEADRDE------------VLNQLRRFLER--YPKARVIITSRPEGYDSSELEG 309
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2025748883 635 ADaIFEVPSFSTRQAQTYMRHYFENsgTAGDKDKALGLLEGQPFLLTHSHSPALCRAVCQLskaLLEQGtetQLPCTLTG 714
Cdd:COG5635 310 FE-VLELAPLSDEQIEEFLKKWFEA--TERKAERLLEALEENPELRELARNPLLLTLLALL---LRERG---ELPDTRAE 380
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2025748883 715 LYVGLL------GPAVRDSPPG----------ALTELAKLAWELGRRHQSTLQGTQLLSEEVRTWAVTQGLVHPTMGTT- 777
Cdd:COG5635 381 LYEQFVelllerWDEQRGLTIYrelsreelreLLSELALAMQENGRTEFAREELEEILREYLGRRKDAEALLDELLLRTg 460
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2025748883 778 ------ETQLAFSSFLLQCFLGAVWLAqcneirdkELPQYLALTPRKKRPYDNWLEGVPRFLTGLVFQPRAHC--LGALM 849
Cdd:COG5635 461 llvergEGRYSFAHRSFQEYLAARALV--------EELDEELLELLAEHLEDPRWREVLLLLAGLLDDVKQIKelIDALL 532
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2025748883 850 EPAVADRKRKVLTRYLKRLKLGSLRAGRLLELLHCAHETQEPGIWEHVVHQLPGHLSFLGTRLTPPDVHVLGRALETASQ 929
Cdd:COG5635 533 ARDDAAALALAAALLLALLLALALLALLALLLLLRLLLALLALLLLALLLLLLLALLLALLALDLGLAALLLLLLLLLLL 612
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2025748883 930 DFSLDLRQTGIEPSGLGNLVGLSCVTSFRAALSDTMVLWESLRHQGEPQLLQAAEEKFTLEPFKAKSPKDVEDLDSLVQT 1009
Cdd:COG5635 613 LLLLALALLLALLLLLLLLLLAELLLLALLALVLLSLLLASRLLLITLLLLAAASAALLLLLLLLLAELLLALLALASLL 692
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2025748883 1010 QRLRNPSEDAALDLPAIRDLKKLEFALDSLSENKIGDEGVSRLAATFTQLKVLETLNLSQNSITDVGACKLAEALPALAK 1089
Cdd:COG5635 693 LLLLLALALALALLLLAVLLAAALDLLLLLVLLLALLLVLALALSLLLLALALLLAGALLLESSALLAVLLASLLLALLL 772
|
730 740
....*....|....*....|....*
gi 2025748883 1090 SLLRLSSLYNNCICDAGARSLAQVL 1114
Cdd:COG5635 773 LSLLLLLVLLLALALLASLLLALLL 797
|
|
| NLRC4_HD2 |
pfam17776 |
NLRC4 helical domain HD2; This entry represents a helical domain found in the NLRC4 protein ... |
788-890 |
1.17e-07 |
|
NLRC4 helical domain HD2; This entry represents a helical domain found in the NLRC4 protein and NOD2 protein.
Pssm-ID: 465499 [Multi-domain] Cd Length: 122 Bit Score: 51.52 E-value: 1.17e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2025748883 788 LQCFLGAVWLAQCNEIRDKELPQYLaLTPRKKRPYDNWLEGVP-----------RFLTGLVFQPRAHCLGALMEPAVADR 856
Cdd:pfam17776 4 FQEFFAALFYVLSFKEEKSNPLKEF-FGLRKRESLKSLLDKALksknghldlflRFLFGLLNEENQRLLEGLLGCKLSSE 82
|
90 100 110
....*....|....*....|....*....|....
gi 2025748883 857 KRKVLTRYLKRLKLGSLRAGRLLELLHCAHETQE 890
Cdd:pfam17776 83 IKQELLQWIKSLIQKELSSERFLNLFHCLYELQD 116
|
|
| RNA1 |
COG5238 |
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ... |
1038-1151 |
1.67e-07 |
|
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];
Pssm-ID: 444072 [Multi-domain] Cd Length: 434 Bit Score: 55.18 E-value: 1.67e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2025748883 1038 SLSENKIGDEGVSRLAATFTQLKVLETLNLSQNSITDVGACKLAEALpALAKSLLRLSSLYNNcICDAGARSLAQVLpDM 1117
Cdd:COG5238 326 NLAYNGIGAQGAIALAKALQENTTLHSLDLSDNQIGDEGAIALAKYL-EGNTTLRELNLGKNN-IGKQGAEALIDAL-QT 402
|
90 100 110
....*....|....*....|....*....|....
gi 2025748883 1118 VSLRVMDVQFNKFTAAGAQQLassLQKCPQVETL 1151
Cdd:COG5238 403 NRLHTLILDGNLIGAEAQQRL---EQLLERIKSV 433
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
993-1151 |
7.63e-07 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 53.01 E-value: 7.63e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2025748883 993 KAKSPKDVEDLDSLVQTQRLRNPSEDAALDLPAIRDLKKLEFaLDsLSENKIGDegvsrLAATFTQLKVLETLNLSQNSI 1072
Cdd:COG4886 76 LLSLLLLSLLLLGLTDLGDLTNLTELDLSGNEELSNLTNLES-LD-LSGNQLTD-----LPEELANLTNLKELDLSNNQL 148
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2025748883 1073 TDvgackLAEALPALaKSLLRLsSLYNNCIcdagaRSLAQVLPDMVSLRVMDVQFNKFTAagaqqLASSLQKCPQVETL 1151
Cdd:COG4886 149 TD-----LPEPLGNL-TNLKSL-DLSNNQL-----TDLPEELGNLTNLKELDLSNNQITD-----LPEPLGNLTNLEEL 210
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
1022-1131 |
9.52e-06 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 49.55 E-value: 9.52e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2025748883 1022 DLPA-IRDLKKLEFaLDsLSENKIGDegvsrLAATFTQLKVLETLNLSQNSITDvgackLAEALPALaKSLLRLsSLYNN 1100
Cdd:COG4886 173 DLPEeLGNLTNLKE-LD-LSNNQITD-----LPEPLGNLTNLEELDLSGNQLTD-----LPEPLANL-TNLETL-DLSNN 238
|
90 100 110
....*....|....*....|....*....|.
gi 2025748883 1101 CIcdagaRSLAQvLPDMVSLRVMDVQFNKFT 1131
Cdd:COG4886 239 QL-----TDLPE-LGNLTNLEELDLSNNQLT 263
|
|
| PHA03377 |
PHA03377 |
EBNA-3C; Provisional |
197-425 |
1.14e-05 |
|
EBNA-3C; Provisional
Pssm-ID: 177614 [Multi-domain] Cd Length: 1000 Bit Score: 49.67 E-value: 1.14e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2025748883 197 IERIETEEGFSESME---VPVEAGERSQKRRS----PEEHPMDPKHRKLAEPSMVPMLTGSFLMGPASISTMPYLPPALS 269
Cdd:PHA03377 517 VETTEEEESVTQPAKphrKVQDGFQRSGRRQKratpPKVSPSDRGPPKASPPVMAPPSTGPRVMATPSTGPRDMAPPSTG 596
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2025748883 270 NQEPVSCHIHLEGATQTSVPPSRSSPNCLDLTIGHI----QLLPT----LPQGLWQIQgAGTGLPSVliyhgEMPQVNHV 341
Cdd:PHA03377 597 PRQQAKCKDGPPASGPHEKQPPSSAPRDMAPSVVRMflreRLLEQstgpKPKSFWEMR-AGRDGSGI-----QQEPSSRR 670
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2025748883 342 IPSGSPTvsslpksPDRPCstspFAPSVADLPSMPepaltsrvneaedTTSPSPCQEGPESPIKlPKWPASverfqHSLK 421
Cdd:PHA03377 671 QPATQST-------PPRPS----WLPSVFVLPSVD-------------AGRAQPSEESHLSSMS-PTQPIS-----HEEQ 720
|
....
gi 2025748883 422 DKYQ 425
Cdd:PHA03377 721 PRYE 724
|
|
| Atrophin-1 |
pfam03154 |
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ... |
220-506 |
3.21e-05 |
|
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.
Pssm-ID: 460830 [Multi-domain] Cd Length: 991 Bit Score: 48.22 E-value: 3.21e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2025748883 220 SQKRRSPEEHPMDPK-----HRKLAEPSMVPMLTG-------SFLMGPASISTMPYLPP--------ALSNQEPVSCHih 279
Cdd:pfam03154 334 LQSQQPPREQPLPPAplsmpHIKPPPTTPIPQLPNpqshkhpPHLSGPSPFQMNSNLPPppalkplsSLSTHHPPSAH-- 411
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2025748883 280 legatqtsVPPSRSSPNCLDLtighiQLLPTLPQGLWQIQG---AGTGLPSVLIYHGEMPQ----VNHVIPSGSPTVSSl 352
Cdd:pfam03154 412 --------PPPLQLMPQSQQL-----PPPPAQPPVLTQSQSlppPAASHPPTSGLHQVPSQspfpQHPFVPGGPPPITP- 477
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2025748883 353 PKSPdrPCSTSPFAP------SVADLPSMPEPALTSRV-----------NEAEDTTSPSPCQEGPESP---IKLPKWPAS 412
Cdd:pfam03154 478 PSGP--PTSTSSAMPgiqppsSASVSSSGPVPAAVSCPlppvqikeealDEAEEPESPPPPPRSPSPEptvVNTPSHASQ 555
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2025748883 413 VERFQHSLKDKYQ--VEPENLSVPMVAVELVRARLERGSNKSQERELATPDWTERQLARGGldqvlqavvDRRRPRETQV 490
Cdd:pfam03154 556 SARFYKHLDRGYNscARTDLYFMPLAGSKLAKKREEALEKAKREAEQKAREEKEREKEKEK---------ERERERERER 626
|
330
....*....|....*.
gi 2025748883 491 VAVLGKAGQGKSHWAR 506
Cdd:pfam03154 627 EAERAAKASSSSHEGR 642
|
|
| LRR_RI |
smart00368 |
Leucine rich repeat, ribonuclease inhibitor type; |
1089-1116 |
1.54e-03 |
|
Leucine rich repeat, ribonuclease inhibitor type;
Pssm-ID: 197686 [Multi-domain] Cd Length: 28 Bit Score: 37.00 E-value: 1.54e-03
10 20
....*....|....*....|....*...
gi 2025748883 1089 KSLLRLSsLYNNCICDAGARSLAQVLPD 1116
Cdd:smart00368 2 PSLRELD-LSNNKLGDEGARALAEALKD 28
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
1022-1100 |
5.22e-03 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 40.69 E-value: 5.22e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2025748883 1022 DLPAIRDLKKLEFaLDsLSENKIGDEGVSrlaatfTQLKVLETLNLSQNSITDVGACKLAEALPALAKSLLRLSSLYNN 1100
Cdd:COG4886 242 DLPELGNLTNLEE-LD-LSNNQLTDLPPL------ANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLE 312
|
|
| PRK15387 |
PRK15387 |
type III secretion system effector E3 ubiquitin transferase SspH2; |
241-394 |
7.50e-03 |
|
type III secretion system effector E3 ubiquitin transferase SspH2;
Pssm-ID: 185285 [Multi-domain] Cd Length: 788 Bit Score: 40.53 E-value: 7.50e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2025748883 241 PSMVPMLTGSFLMGPASISTMPYLPPALSNQEpvschihLEGATQTSVPPsrSSPNCLDLTI--GHIQLLPTLPQGLWQI 318
Cdd:PRK15387 217 PDCLPAHITTLVIPDNNLTSLPALPPELRTLE-------VSGNQLTSLPV--LPPGLLELSIfsNPLTHLPALPSGLCKL 287
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 2025748883 319 QGAGTGLPSVLIyhgeMPQVNHVIPSGSPTVSSLPKSPDRPCSTSPFAPSVADLPSMPEPALTSRVNEAEDTTSPS 394
Cdd:PRK15387 288 WIFGNQLTSLPV----LPPGLQELSVSDNQLASLPALPSELCKLWAYNNQLTSLPTLPSGLQELSVSDNQLASLPT 359
|
|
| |
