|
Name |
Accession |
Description |
Interval |
E-value |
| PPP1R42 super family |
cl42388 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
763-1088 |
7.35e-37 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
The actual alignment was detected with superfamily member cd00116:
Pssm-ID: 455733 [Multi-domain] Cd Length: 319 Bit Score: 141.72 E-value: 7.35e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2043829276 763 YIRRLQINTLCPERLLELLCCVYETQnnyLLQHVALrlEPELSFLGIVLTPP--DVHVLHSVLKRSRKEFSLDLQnssid 840
Cdd:cd00116 4 SLKGELLKTERATELLPKLLCLQVLR---LEGNTLG--EEAAKALASALRPQpsLKELCLSLNETGRIPRGLQSL----- 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2043829276 841 MQGLQALVSLRNVTSFRASLS-DTVRLWKSLEQTKDYELLK---ASTEKFVLdPFKAKTMKDISdlSDLVELQekMMNCV 916
Cdd:cd00116 74 LQGLTKGCGLQELDLSDNALGpDGCGVLESLLRSSSLQELKlnnNGLGDRGL-RLLAKGLKDLP--PALEKLV--LGRNR 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2043829276 917 QEASGCT--SYEIPAIRNLRKLEFALGPAcGLQGLLKLVKILAAFPSLQHLDLDalsENSIGDEGAKSLSEVFPTLTSLE 994
Cdd:cd00116 149 LEGASCEalAKALRANRDLKELNLANNGI-GDAGIRALAEGLKANCNLEVLDLN---NNGLTDEGASALAETLASLKSLE 224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2043829276 995 TLNLSQNKITDVGAENLATALPSLSSL-KTLSLYNNNICDFGAENLAKVLPAMTSLRVLDVQYNKITGVGAQQLtDSLRK 1073
Cdd:cd00116 225 VLNLGDNNLTDAGAAALASALLSPNISlLTLSLSCNDITDDGAKDLAEVLAEKESLLELDLRGNKFGEEGAQLL-AESLL 303
|
330
....*....|....*
gi 2043829276 1074 CPHMKNLVMWNPTIP 1088
Cdd:cd00116 304 EPGNELESLWVKDDS 318
|
|
| NACHT |
pfam05729 |
NACHT domain; This NTPase domain is found in apoptosis proteins as well as those involved in ... |
377-547 |
4.95e-32 |
|
NACHT domain; This NTPase domain is found in apoptosis proteins as well as those involved in MHC transcription activation. This family is closely related to pfam00931.
:
Pssm-ID: 428606 [Multi-domain] Cd Length: 166 Bit Score: 122.80 E-value: 4.95e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2043829276 377 VIVVLGKAGMGKSILIQKICQDWSNGE-FSQFEFVFWFDCKQLSLPEKQYSLKELLLEFFVKPQEGSKEIFEYMLQNPGK 455
Cdd:pfam05729 2 TVILQGEAGSGKTTLLQKLALLWAQGKlPQGFDFVFFLPCRELSRSGNARSLADLLFSQWPEPAAPVSEVWAVILELPER 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2043829276 456 VLLIFDGFKGLHDHENFPRcsasqpekDLCSIKELLSGLIQKKVLNGCTLLFTARPK--DKLYQYMSKVDkTIEIVGFSP 533
Cdd:pfam05729 82 LLLILDGLDELVSDLGQLD--------GPCPVLTLLSSLLRKKLLPGASLLLTVRPDalRDLRRGLEEPR-YLEVRGFSE 152
|
170
....*....|....
gi 2043829276 534 QQRELYITKYFEES 547
Cdd:pfam05729 153 SDRKQYVRKYFSDE 166
|
|
| NLRC4_HD2 super family |
cl39284 |
NLRC4 helical domain HD2; This entry represents a helical domain found in the NLRC4 protein ... |
723-795 |
2.07e-04 |
|
NLRC4 helical domain HD2; This entry represents a helical domain found in the NLRC4 protein and NOD2 protein.
The actual alignment was detected with superfamily member pfam17776:
Pssm-ID: 465499 [Multi-domain] Cd Length: 122 Bit Score: 42.28 E-value: 2.07e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2043829276 723 LDLMPRFLAGL------MFLQDdpSFCSLSNEDEKQStkkqktLLKYIRRLQINTLCPERLLELLCCVYETQNNYLLQH 795
Cdd:pfam17776 52 LDLFLRFLFGLlneenqRLLEG--LLGCKLSSEIKQE------LLQWIKSLIQKELSSERFLNLFHCLYELQDESFVKE 122
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| LRR_RI |
cd00116 |
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ... |
763-1088 |
7.35e-37 |
|
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).
Pssm-ID: 238064 [Multi-domain] Cd Length: 319 Bit Score: 141.72 E-value: 7.35e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2043829276 763 YIRRLQINTLCPERLLELLCCVYETQnnyLLQHVALrlEPELSFLGIVLTPP--DVHVLHSVLKRSRKEFSLDLQnssid 840
Cdd:cd00116 4 SLKGELLKTERATELLPKLLCLQVLR---LEGNTLG--EEAAKALASALRPQpsLKELCLSLNETGRIPRGLQSL----- 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2043829276 841 MQGLQALVSLRNVTSFRASLS-DTVRLWKSLEQTKDYELLK---ASTEKFVLdPFKAKTMKDISdlSDLVELQekMMNCV 916
Cdd:cd00116 74 LQGLTKGCGLQELDLSDNALGpDGCGVLESLLRSSSLQELKlnnNGLGDRGL-RLLAKGLKDLP--PALEKLV--LGRNR 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2043829276 917 QEASGCT--SYEIPAIRNLRKLEFALGPAcGLQGLLKLVKILAAFPSLQHLDLDalsENSIGDEGAKSLSEVFPTLTSLE 994
Cdd:cd00116 149 LEGASCEalAKALRANRDLKELNLANNGI-GDAGIRALAEGLKANCNLEVLDLN---NNGLTDEGASALAETLASLKSLE 224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2043829276 995 TLNLSQNKITDVGAENLATALPSLSSL-KTLSLYNNNICDFGAENLAKVLPAMTSLRVLDVQYNKITGVGAQQLtDSLRK 1073
Cdd:cd00116 225 VLNLGDNNLTDAGAAALASALLSPNISlLTLSLSCNDITDDGAKDLAEVLAEKESLLELDLRGNKFGEEGAQLL-AESLL 303
|
330
....*....|....*
gi 2043829276 1074 CPHMKNLVMWNPTIP 1088
Cdd:cd00116 304 EPGNELESLWVKDDS 318
|
|
| NACHT |
pfam05729 |
NACHT domain; This NTPase domain is found in apoptosis proteins as well as those involved in ... |
377-547 |
4.95e-32 |
|
NACHT domain; This NTPase domain is found in apoptosis proteins as well as those involved in MHC transcription activation. This family is closely related to pfam00931.
Pssm-ID: 428606 [Multi-domain] Cd Length: 166 Bit Score: 122.80 E-value: 4.95e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2043829276 377 VIVVLGKAGMGKSILIQKICQDWSNGE-FSQFEFVFWFDCKQLSLPEKQYSLKELLLEFFVKPQEGSKEIFEYMLQNPGK 455
Cdd:pfam05729 2 TVILQGEAGSGKTTLLQKLALLWAQGKlPQGFDFVFFLPCRELSRSGNARSLADLLFSQWPEPAAPVSEVWAVILELPER 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2043829276 456 VLLIFDGFKGLHDHENFPRcsasqpekDLCSIKELLSGLIQKKVLNGCTLLFTARPK--DKLYQYMSKVDkTIEIVGFSP 533
Cdd:pfam05729 82 LLLILDGLDELVSDLGQLD--------GPCPVLTLLSSLLRKKLLPGASLLLTVRPDalRDLRRGLEEPR-YLEVRGFSE 152
|
170
....*....|....
gi 2043829276 534 QQRELYITKYFEES 547
Cdd:pfam05729 153 SDRKQYVRKYFSDE 166
|
|
| NACHT |
COG5635 |
Predicted NTPase, NACHT family domain [Signal transduction mechanisms]; |
372-674 |
1.10e-21 |
|
Predicted NTPase, NACHT family domain [Signal transduction mechanisms];
Pssm-ID: 444362 [Multi-domain] Cd Length: 935 Bit Score: 101.81 E-value: 1.10e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2043829276 372 DLETKVIVVLGKAGMGKSILIQKICQDWSNGEFSQFEFV-FWFDCKQLSlpeKQYSLKELLLEFFVKPQEGSKEIFEYML 450
Cdd:COG5635 177 EAKKKRLLILGEPGSGKTTLLRYLALELAERYLDAEDPIpILIELRDLA---EEASLEDLLAEALEKRGGEPEDALERLL 253
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2043829276 451 QNpGKVLLIFDGFkglhDhENFPRCSASQPEKDlcsIKELLSGliqkkvLNGCTLLFTARPKDKLYQYMSKVDkTIEIVG 530
Cdd:COG5635 254 RN-GRLLLLLDGL----D-EVPDEADRDEVLNQ---LRRFLER------YPKARVIITSRPEGYDSSELEGFE-VLELAP 317
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2043829276 531 FSPQQRELYITKYFEESLYC-DSALKLIKECEYLFSHCYSPVMCRFVCFLCEivlemGENSLPSTLTEVFLKFFQ----- 604
Cdd:COG5635 318 LSDEQIEEFLKKWFEATERKaERLLEALEENPELRELARNPLLLTLLALLLR-----ERGELPDTRAELYEQFVElller 392
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2043829276 605 ---QKIMFMQTDVTTTQNQESLATLARVAWCLGEKHqsamksdlIPSKEVKEFALKYgfflpfaLPRHSDSEE 674
Cdd:COG5635 393 wdeQRGLTIYRELSREELRELLSELALAMQENGRTE--------FAREELEEILREY-------LGRRKDAEA 450
|
|
| RNA1 |
COG5238 |
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ... |
945-1073 |
2.45e-19 |
|
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];
Pssm-ID: 444072 [Multi-domain] Cd Length: 434 Bit Score: 92.16 E-value: 2.45e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2043829276 945 GLQGLLKLVKILAAFPSLQHLDLdalSENSIGDEGAKSLSEVFPTLTSLETLNLSQNKITDVGAENLATALPSLSSLKTL 1024
Cdd:COG5238 277 GAEGAIALAKALQGNTTLTSLDL---SVNRIGDEGAIALAEGLQGNKTLHTLNLAYNGIGAQGAIALAKALQENTTLHSL 353
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 2043829276 1025 SLYNNNICDFGAENLAKVLPAMTSLRVLDVQYNKITGVGAQQLTDSLRK 1073
Cdd:COG5238 354 DLSDNQIGDEGAIALAKYLEGNTTLRELNLGKNNIGKQGAEALIDALQT 402
|
|
| NLRC4_HD2 |
pfam17776 |
NLRC4 helical domain HD2; This entry represents a helical domain found in the NLRC4 protein ... |
723-795 |
2.07e-04 |
|
NLRC4 helical domain HD2; This entry represents a helical domain found in the NLRC4 protein and NOD2 protein.
Pssm-ID: 465499 [Multi-domain] Cd Length: 122 Bit Score: 42.28 E-value: 2.07e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2043829276 723 LDLMPRFLAGL------MFLQDdpSFCSLSNEDEKQStkkqktLLKYIRRLQINTLCPERLLELLCCVYETQNNYLLQH 795
Cdd:pfam17776 52 LDLFLRFLFGLlneenqRLLEG--LLGCKLSSEIKQE------LLQWIKSLIQKELSSERFLNLFHCLYELQDESFVKE 122
|
|
| LRR_6 |
pfam13516 |
Leucine Rich repeat; |
989-1012 |
3.39e-03 |
|
Leucine Rich repeat;
Pssm-ID: 463907 [Multi-domain] Cd Length: 24 Bit Score: 35.67 E-value: 3.39e-03
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| LRR_RI |
cd00116 |
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ... |
763-1088 |
7.35e-37 |
|
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).
Pssm-ID: 238064 [Multi-domain] Cd Length: 319 Bit Score: 141.72 E-value: 7.35e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2043829276 763 YIRRLQINTLCPERLLELLCCVYETQnnyLLQHVALrlEPELSFLGIVLTPP--DVHVLHSVLKRSRKEFSLDLQnssid 840
Cdd:cd00116 4 SLKGELLKTERATELLPKLLCLQVLR---LEGNTLG--EEAAKALASALRPQpsLKELCLSLNETGRIPRGLQSL----- 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2043829276 841 MQGLQALVSLRNVTSFRASLS-DTVRLWKSLEQTKDYELLK---ASTEKFVLdPFKAKTMKDISdlSDLVELQekMMNCV 916
Cdd:cd00116 74 LQGLTKGCGLQELDLSDNALGpDGCGVLESLLRSSSLQELKlnnNGLGDRGL-RLLAKGLKDLP--PALEKLV--LGRNR 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2043829276 917 QEASGCT--SYEIPAIRNLRKLEFALGPAcGLQGLLKLVKILAAFPSLQHLDLDalsENSIGDEGAKSLSEVFPTLTSLE 994
Cdd:cd00116 149 LEGASCEalAKALRANRDLKELNLANNGI-GDAGIRALAEGLKANCNLEVLDLN---NNGLTDEGASALAETLASLKSLE 224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2043829276 995 TLNLSQNKITDVGAENLATALPSLSSL-KTLSLYNNNICDFGAENLAKVLPAMTSLRVLDVQYNKITGVGAQQLtDSLRK 1073
Cdd:cd00116 225 VLNLGDNNLTDAGAAALASALLSPNISlLTLSLSCNDITDDGAKDLAEVLAEKESLLELDLRGNKFGEEGAQLL-AESLL 303
|
330
....*....|....*
gi 2043829276 1074 CPHMKNLVMWNPTIP 1088
Cdd:cd00116 304 EPGNELESLWVKDDS 318
|
|
| NACHT |
pfam05729 |
NACHT domain; This NTPase domain is found in apoptosis proteins as well as those involved in ... |
377-547 |
4.95e-32 |
|
NACHT domain; This NTPase domain is found in apoptosis proteins as well as those involved in MHC transcription activation. This family is closely related to pfam00931.
Pssm-ID: 428606 [Multi-domain] Cd Length: 166 Bit Score: 122.80 E-value: 4.95e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2043829276 377 VIVVLGKAGMGKSILIQKICQDWSNGE-FSQFEFVFWFDCKQLSLPEKQYSLKELLLEFFVKPQEGSKEIFEYMLQNPGK 455
Cdd:pfam05729 2 TVILQGEAGSGKTTLLQKLALLWAQGKlPQGFDFVFFLPCRELSRSGNARSLADLLFSQWPEPAAPVSEVWAVILELPER 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2043829276 456 VLLIFDGFKGLHDHENFPRcsasqpekDLCSIKELLSGLIQKKVLNGCTLLFTARPK--DKLYQYMSKVDkTIEIVGFSP 533
Cdd:pfam05729 82 LLLILDGLDELVSDLGQLD--------GPCPVLTLLSSLLRKKLLPGASLLLTVRPDalRDLRRGLEEPR-YLEVRGFSE 152
|
170
....*....|....
gi 2043829276 534 QQRELYITKYFEES 547
Cdd:pfam05729 153 SDRKQYVRKYFSDE 166
|
|
| NACHT |
COG5635 |
Predicted NTPase, NACHT family domain [Signal transduction mechanisms]; |
372-674 |
1.10e-21 |
|
Predicted NTPase, NACHT family domain [Signal transduction mechanisms];
Pssm-ID: 444362 [Multi-domain] Cd Length: 935 Bit Score: 101.81 E-value: 1.10e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2043829276 372 DLETKVIVVLGKAGMGKSILIQKICQDWSNGEFSQFEFV-FWFDCKQLSlpeKQYSLKELLLEFFVKPQEGSKEIFEYML 450
Cdd:COG5635 177 EAKKKRLLILGEPGSGKTTLLRYLALELAERYLDAEDPIpILIELRDLA---EEASLEDLLAEALEKRGGEPEDALERLL 253
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2043829276 451 QNpGKVLLIFDGFkglhDhENFPRCSASQPEKDlcsIKELLSGliqkkvLNGCTLLFTARPKDKLYQYMSKVDkTIEIVG 530
Cdd:COG5635 254 RN-GRLLLLLDGL----D-EVPDEADRDEVLNQ---LRRFLER------YPKARVIITSRPEGYDSSELEGFE-VLELAP 317
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2043829276 531 FSPQQRELYITKYFEESLYC-DSALKLIKECEYLFSHCYSPVMCRFVCFLCEivlemGENSLPSTLTEVFLKFFQ----- 604
Cdd:COG5635 318 LSDEQIEEFLKKWFEATERKaERLLEALEENPELRELARNPLLLTLLALLLR-----ERGELPDTRAELYEQFVElller 392
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 2043829276 605 ---QKIMFMQTDVTTTQNQESLATLARVAWCLGEKHqsamksdlIPSKEVKEFALKYgfflpfaLPRHSDSEE 674
Cdd:COG5635 393 wdeQRGLTIYRELSREELRELLSELALAMQENGRTE--------FAREELEEILREY-------LGRRKDAEA 450
|
|
| RNA1 |
COG5238 |
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ... |
945-1073 |
2.45e-19 |
|
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];
Pssm-ID: 444072 [Multi-domain] Cd Length: 434 Bit Score: 92.16 E-value: 2.45e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2043829276 945 GLQGLLKLVKILAAFPSLQHLDLdalSENSIGDEGAKSLSEVFPTLTSLETLNLSQNKITDVGAENLATALPSLSSLKTL 1024
Cdd:COG5238 277 GAEGAIALAKALQGNTTLTSLDL---SVNRIGDEGAIALAEGLQGNKTLHTLNLAYNGIGAQGAIALAKALQENTTLHSL 353
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 2043829276 1025 SLYNNNICDFGAENLAKVLPAMTSLRVLDVQYNKITGVGAQQLTDSLRK 1073
Cdd:COG5238 354 DLSDNQIGDEGAIALAKYLEGNTTLRELNLGKNNIGKQGAEALIDALQT 402
|
|
| RNA1 |
COG5238 |
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ... |
932-1080 |
1.25e-18 |
|
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];
Pssm-ID: 444072 [Multi-domain] Cd Length: 434 Bit Score: 89.85 E-value: 1.25e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2043829276 932 NLRKLEFALGPAcGLQGLLKLVKILAAFPSLQHLDLdalSENSIGDEGAKSLSEVFPTLTSLETLNLSQNKITDVGAENL 1011
Cdd:COG5238 209 TVTTLWLKRNPI-GDEGAEILAEALKGNKSLTTLDL---SNNQIGDEGVIALAEALKNNTTVETLYLSGNQIGAEGAIAL 284
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2043829276 1012 ATALPSLSSLKTLSLYNNNICDFGAENLAKVLPAMTSLRVLDVQYNKITGVGAQQLTDSLRKCPHMKNL 1080
Cdd:COG5238 285 AKALQGNTTLTSLDLSVNRIGDEGAIALAEGLQGNKTLHTLNLAYNGIGAQGAIALAKALQENTTLHSL 353
|
|
| RNA1 |
COG5238 |
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ... |
945-1073 |
8.38e-17 |
|
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];
Pssm-ID: 444072 [Multi-domain] Cd Length: 434 Bit Score: 84.46 E-value: 8.38e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2043829276 945 GLQGLLKLVKILAAFPSLQHLDLdalSENSIGDEGAKSLSEVFPTLTSLETLNLSQNKITDVGAENLATALPSLSSLKTL 1024
Cdd:COG5238 193 GDEGIEELAEALTQNTTVTTLWL---KRNPIGDEGAEILAEALKGNKSLTTLDLSNNQIGDEGVIALAEALKNNTTVETL 269
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 2043829276 1025 SLYNNNICDFGAENLAKVLPAMTSLRVLDVQYNKITGVGAQQLTDSLRK 1073
Cdd:COG5238 270 YLSGNQIGAEGAIALAKALQGNTTLTSLDLSVNRIGDEGAIALAEGLQG 318
|
|
| RNA1 |
COG5238 |
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ... |
945-1080 |
1.57e-14 |
|
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];
Pssm-ID: 444072 [Multi-domain] Cd Length: 434 Bit Score: 77.14 E-value: 1.57e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2043829276 945 GLQGLLKLVKILAAFPSLQHLDLdalSENSIGDEGAKSLSEVFPTLTSLETLNLSQNKITDVGAENLATALPSLSSLKTL 1024
Cdd:COG5238 249 GDEGVIALAEALKNNTTVETLYL---SGNQIGAEGAIALAKALQGNTTLTSLDLSVNRIGDEGAIALAEGLQGNKTLHTL 325
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*.
gi 2043829276 1025 SLYNNNICDFGAENLAKVLPAMTSLRVLDVQYNKITGVGAQQLTDSLRKCPHMKNL 1080
Cdd:COG5238 326 NLAYNGIGAQGAIALAKALQENTTLHSLDLSDNQIGDEGAIALAKYLEGNTTLREL 381
|
|
| RNA1 |
COG5238 |
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ... |
963-1083 |
3.96e-13 |
|
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];
Pssm-ID: 444072 [Multi-domain] Cd Length: 434 Bit Score: 72.90 E-value: 3.96e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2043829276 963 QHLDLDALSENSIGDEGAKSLSEVFPTLTSLETLNLSQNKITDVGAENLATALPSLSSLKTLSLYNNNICDFGAENLAKV 1042
Cdd:COG5238 180 NSVETVYLGCNQIGDEGIEELAEALTQNTTVTTLWLKRNPIGDEGAEILAEALKGNKSLTTLDLSNNQIGDEGVIALAEA 259
|
90 100 110 120
....*....|....*....|....*....|....*....|.
gi 2043829276 1043 LPAMTSLRVLDVQYNKITGVGAQQLTDSLRKCPHMKNLVMW 1083
Cdd:COG5238 260 LKNNTTVETLYLSGNQIGAEGAIALAKALQGNTTLTSLDLS 300
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
823-1099 |
8.41e-10 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 62.26 E-value: 8.41e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2043829276 823 LKRSRKEFSLDLQNSSIDMQGLQALVSLRNVTSFRASLSDTVRLWKSLEQTKDYELLKASTEKFVLDPFKAKTMKDISDL 902
Cdd:COG4886 5 LLSLTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSL 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2043829276 903 SDLVELQEKMMNCVQEASGCTSYEIPAIRNLRKLEfalgpaCGLQGLLKLVKILAAFPSLQHLDLdalSENSIgdegaKS 982
Cdd:COG4886 85 LLLGLTDLGDLTNLTELDLSGNEELSNLTNLESLD------LSGNQLTDLPEELANLTNLKELDL---SNNQL-----TD 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2043829276 983 LSEVFPTLTSLETLNLSQNKITDVGAE----------NLatalpslsslktlslYNNNIcdfgaENLAKVLPAMTSLRVL 1052
Cdd:COG4886 151 LPEPLGNLTNLKSLDLSNNQLTDLPEElgnltnlkelDL---------------SNNQI-----TDLPEPLGNLTNLEEL 210
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|.
gi 2043829276 1053 DVQYNKITgvgaqQLTDSLRKCPHMKNLVMWN---PTIPY-GVLEHLHQLD 1099
Cdd:COG4886 211 DLSGNQLT-----DLPEPLANLTNLETLDLSNnqlTDLPElGNLTNLEELD 256
|
|
| NLRC4_HD2 |
pfam17776 |
NLRC4 helical domain HD2; This entry represents a helical domain found in the NLRC4 protein ... |
723-795 |
2.07e-04 |
|
NLRC4 helical domain HD2; This entry represents a helical domain found in the NLRC4 protein and NOD2 protein.
Pssm-ID: 465499 [Multi-domain] Cd Length: 122 Bit Score: 42.28 E-value: 2.07e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 2043829276 723 LDLMPRFLAGL------MFLQDdpSFCSLSNEDEKQStkkqktLLKYIRRLQINTLCPERLLELLCCVYETQNNYLLQH 795
Cdd:pfam17776 52 LDLFLRFLFGLlneenqRLLEG--LLGCKLSSEIKQE------LLQWIKSLIQKELSSERFLNLFHCLYELQDESFVKE 122
|
|
| LRR_6 |
pfam13516 |
Leucine Rich repeat; |
989-1012 |
3.39e-03 |
|
Leucine Rich repeat;
Pssm-ID: 463907 [Multi-domain] Cd Length: 24 Bit Score: 35.67 E-value: 3.39e-03
|
| |
