|
Name |
Accession |
Description |
Interval |
E-value |
| PPP1R42 super family |
cl42388 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
768-1093 |
8.55e-35 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
The actual alignment was detected with superfamily member cd00116:
Pssm-ID: 455733 [Multi-domain] Cd Length: 319 Bit Score: 135.95 E-value: 8.55e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024357723 768 YIKRLQIDNLCPERLLELLHCIYETQNSYLLQHVAlrlkpDLSFLGIVLTPP--DVHVLSSTLKRSRKEFSLDLQnssid 845
Cdd:cd00116 4 SLKGELLKTERATELLPKLLCLQVLRLEGNTLGEE-----AAKALASALRPQpsLKELCLSLNETGRIPRGLQSL----- 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024357723 846 THGLKDLVGLKNVVSFRASLS-DTIRLWKYLEQTKDYELLRVSTEKFVLD--PFKAKTMRDII-DLSDLVEMQeiiiNRV 921
Cdd:cd00116 74 LQGLTKGCGLQELDLSDNALGpDGCGVLESLLRSSSLQELKLNNNGLGDRglRLLAKGLKDLPpALEKLVLGR----NRL 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024357723 922 QDDSGCS-SYQIPAIKNLRKLEFALGPAcGLQGFLKLVEILAAFPSLQHLDLDalsENGIGDEGAKSLSEVFPTLTSLET 1000
Cdd:cd00116 150 EGASCEAlAKALRANRDLKELNLANNGI-GDAGIRALAEGLKANCNLEVLDLN---NNGLTDEGASALAETLASLKSLEV 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024357723 1001 LNLSQNKITDVGAEKLATALPSLSSL-TTLSLYNNSICDFGAENLAKVLPAMASLRVLDIQYNKITDVGAQQLtDSLRKC 1079
Cdd:cd00116 226 LNLGDNNLTDAGAAALASALLSPNISlLTLSLSCNDITDDGAKDLAEVLAEKESLLELDLRGNKFGEEGAQLL-AESLLE 304
|
330
....*....|....
gi 2024357723 1080 PHIKNLVMWNPTIP 1093
Cdd:cd00116 305 PGNELESLWVKDDS 318
|
|
| NACHT |
pfam05729 |
NACHT domain; This NTPase domain is found in apoptosis proteins as well as those involved in ... |
379-547 |
3.76e-32 |
|
NACHT domain; This NTPase domain is found in apoptosis proteins as well as those involved in MHC transcription activation. This family is closely related to pfam00931.
:
Pssm-ID: 428606 [Multi-domain] Cd Length: 166 Bit Score: 123.18 E-value: 3.76e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024357723 379 VIVVLGKAGMGKSVLVQKICQDWSNGE-FSQFEFVFWFDCKQISLPEKWYSLKDLLLDFFVRPQEGSKEIFEYILQNSTK 457
Cdd:pfam05729 2 TVILQGEAGSGKTTLLQKLALLWAQGKlPQGFDFVFFLPCRELSRSGNARSLADLLFSQWPEPAAPVSEVWAVILELPER 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024357723 458 VLLVFDGLEGLhghenspqCSASQPNKDLCRVKELLSGLIQKKILNGCTLLLTARTK--EKVCQYVSKVDkTIEIVGFSP 535
Cdd:pfam05729 82 LLLILDGLDEL--------VSDLGQLDGPCPVLTLLSSLLRKKLLPGASLLLTVRPDalRDLRRGLEEPR-YLEVRGFSE 152
|
170
....*....|..
gi 2024357723 536 WQRELYISKYFE 547
Cdd:pfam05729 153 SDRKQYVRKYFS 164
|
|
| NLRC4_HD2 super family |
cl39284 |
NLRC4 helical domain HD2; This entry represents a helical domain found in the NLRC4 protein ... |
691-800 |
4.59e-11 |
|
NLRC4 helical domain HD2; This entry represents a helical domain found in the NLRC4 protein and NOD2 protein.
The actual alignment was detected with superfamily member pfam17776:
Pssm-ID: 465499 [Multi-domain] Cd Length: 122 Bit Score: 61.15 E-value: 4.59e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024357723 691 IQNFLGALHLILTEGIKNKSLIKyLSFPSKKKKPY-------------NWLHFVpRFLAGLL------FLQDdTYFCSLS 751
Cdd:pfam17776 4 FQEFFAALFYVLSFKEEKSNPLK-EFFGLRKRESLkslldkalkskngHLDLFL-RFLFGLLneenqrLLEG-LLGCKLS 80
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 2024357723 752 nkgvkkSTKKQKmLLKYIKRLQIDNLCPERLLELLHCIYETQNSYLLQH 800
Cdd:pfam17776 81 ------SEIKQE-LLQWIKSLIQKELSSERFLNLFHCLYELQDESFVKE 122
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| LRR_RI |
cd00116 |
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ... |
768-1093 |
8.55e-35 |
|
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).
Pssm-ID: 238064 [Multi-domain] Cd Length: 319 Bit Score: 135.95 E-value: 8.55e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024357723 768 YIKRLQIDNLCPERLLELLHCIYETQNSYLLQHVAlrlkpDLSFLGIVLTPP--DVHVLSSTLKRSRKEFSLDLQnssid 845
Cdd:cd00116 4 SLKGELLKTERATELLPKLLCLQVLRLEGNTLGEE-----AAKALASALRPQpsLKELCLSLNETGRIPRGLQSL----- 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024357723 846 THGLKDLVGLKNVVSFRASLS-DTIRLWKYLEQTKDYELLRVSTEKFVLD--PFKAKTMRDII-DLSDLVEMQeiiiNRV 921
Cdd:cd00116 74 LQGLTKGCGLQELDLSDNALGpDGCGVLESLLRSSSLQELKLNNNGLGDRglRLLAKGLKDLPpALEKLVLGR----NRL 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024357723 922 QDDSGCS-SYQIPAIKNLRKLEFALGPAcGLQGFLKLVEILAAFPSLQHLDLDalsENGIGDEGAKSLSEVFPTLTSLET 1000
Cdd:cd00116 150 EGASCEAlAKALRANRDLKELNLANNGI-GDAGIRALAEGLKANCNLEVLDLN---NNGLTDEGASALAETLASLKSLEV 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024357723 1001 LNLSQNKITDVGAEKLATALPSLSSL-TTLSLYNNSICDFGAENLAKVLPAMASLRVLDIQYNKITDVGAQQLtDSLRKC 1079
Cdd:cd00116 226 LNLGDNNLTDAGAAALASALLSPNISlLTLSLSCNDITDDGAKDLAEVLAEKESLLELDLRGNKFGEEGAQLL-AESLLE 304
|
330
....*....|....
gi 2024357723 1080 PHIKNLVMWNPTIP 1093
Cdd:cd00116 305 PGNELESLWVKDDS 318
|
|
| NACHT |
pfam05729 |
NACHT domain; This NTPase domain is found in apoptosis proteins as well as those involved in ... |
379-547 |
3.76e-32 |
|
NACHT domain; This NTPase domain is found in apoptosis proteins as well as those involved in MHC transcription activation. This family is closely related to pfam00931.
Pssm-ID: 428606 [Multi-domain] Cd Length: 166 Bit Score: 123.18 E-value: 3.76e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024357723 379 VIVVLGKAGMGKSVLVQKICQDWSNGE-FSQFEFVFWFDCKQISLPEKWYSLKDLLLDFFVRPQEGSKEIFEYILQNSTK 457
Cdd:pfam05729 2 TVILQGEAGSGKTTLLQKLALLWAQGKlPQGFDFVFFLPCRELSRSGNARSLADLLFSQWPEPAAPVSEVWAVILELPER 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024357723 458 VLLVFDGLEGLhghenspqCSASQPNKDLCRVKELLSGLIQKKILNGCTLLLTARTK--EKVCQYVSKVDkTIEIVGFSP 535
Cdd:pfam05729 82 LLLILDGLDEL--------VSDLGQLDGPCPVLTLLSSLLRKKLLPGASLLLTVRPDalRDLRRGLEEPR-YLEVRGFSE 152
|
170
....*....|..
gi 2024357723 536 WQRELYISKYFE 547
Cdd:pfam05729 153 SDRKQYVRKYFS 164
|
|
| RNA1 |
COG5238 |
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ... |
869-1085 |
4.08e-21 |
|
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];
Pssm-ID: 444072 [Multi-domain] Cd Length: 434 Bit Score: 97.55 E-value: 4.08e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024357723 869 IRLWKYLEQTKDYELLRV-----STEKFVLDPFKAKTMRDIIDLSDlvemqeiiiNRVQDDsGCSSY--QIPAIKNLRKL 941
Cdd:COG5238 144 IQVLKDPLGGNAVHLLGLaarlgLLAAISMAKALQNNSVETVYLGC---------NQIGDE-GIEELaeALTQNTTVTTL 213
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024357723 942 EFALGPAcGLQGFLKLVEILAAFPSLQHLDLdalSENGIGDEGAKSLSEVFPTLTSLETLNLSQNKITDVGAEKLATALP 1021
Cdd:COG5238 214 WLKRNPI-GDEGAEILAEALKGNKSLTTLDL---SNNQIGDEGVIALAEALKNNTTVETLYLSGNQIGAEGAIALAKALQ 289
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2024357723 1022 SLSSLTTLSLYNNSICDFGAENLAKVLPAMASLRVLDIQYNKITDVGAQQLTDSLRKCPHIKNL 1085
Cdd:COG5238 290 GNTTLTSLDLSVNRIGDEGAIALAEGLQGNKTLHTLNLAYNGIGAQGAIALAKALQENTTLHSL 353
|
|
| NLRC4_HD2 |
pfam17776 |
NLRC4 helical domain HD2; This entry represents a helical domain found in the NLRC4 protein ... |
691-800 |
4.59e-11 |
|
NLRC4 helical domain HD2; This entry represents a helical domain found in the NLRC4 protein and NOD2 protein.
Pssm-ID: 465499 [Multi-domain] Cd Length: 122 Bit Score: 61.15 E-value: 4.59e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024357723 691 IQNFLGALHLILTEGIKNKSLIKyLSFPSKKKKPY-------------NWLHFVpRFLAGLL------FLQDdTYFCSLS 751
Cdd:pfam17776 4 FQEFFAALFYVLSFKEEKSNPLK-EFFGLRKRESLkslldkalkskngHLDLFL-RFLFGLLneenqrLLEG-LLGCKLS 80
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 2024357723 752 nkgvkkSTKKQKmLLKYIKRLQIDNLCPERLLELLHCIYETQNSYLLQH 800
Cdd:pfam17776 81 ------SEIKQE-LLQWIKSLIQKELSSERFLNLFHCLYELQDESFVKE 122
|
|
| LRR_6 |
pfam13516 |
Leucine Rich repeat; |
994-1017 |
6.74e-04 |
|
Leucine Rich repeat;
Pssm-ID: 463907 [Multi-domain] Cd Length: 24 Bit Score: 37.99 E-value: 6.74e-04
|
| LRR_RI |
smart00368 |
Leucine rich repeat, ribonuclease inhibitor type; |
995-1020 |
1.13e-03 |
|
Leucine rich repeat, ribonuclease inhibitor type;
Pssm-ID: 197686 [Multi-domain] Cd Length: 28 Bit Score: 37.39 E-value: 1.13e-03
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| LRR_RI |
cd00116 |
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ... |
768-1093 |
8.55e-35 |
|
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).
Pssm-ID: 238064 [Multi-domain] Cd Length: 319 Bit Score: 135.95 E-value: 8.55e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024357723 768 YIKRLQIDNLCPERLLELLHCIYETQNSYLLQHVAlrlkpDLSFLGIVLTPP--DVHVLSSTLKRSRKEFSLDLQnssid 845
Cdd:cd00116 4 SLKGELLKTERATELLPKLLCLQVLRLEGNTLGEE-----AAKALASALRPQpsLKELCLSLNETGRIPRGLQSL----- 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024357723 846 THGLKDLVGLKNVVSFRASLS-DTIRLWKYLEQTKDYELLRVSTEKFVLD--PFKAKTMRDII-DLSDLVEMQeiiiNRV 921
Cdd:cd00116 74 LQGLTKGCGLQELDLSDNALGpDGCGVLESLLRSSSLQELKLNNNGLGDRglRLLAKGLKDLPpALEKLVLGR----NRL 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024357723 922 QDDSGCS-SYQIPAIKNLRKLEFALGPAcGLQGFLKLVEILAAFPSLQHLDLDalsENGIGDEGAKSLSEVFPTLTSLET 1000
Cdd:cd00116 150 EGASCEAlAKALRANRDLKELNLANNGI-GDAGIRALAEGLKANCNLEVLDLN---NNGLTDEGASALAETLASLKSLEV 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024357723 1001 LNLSQNKITDVGAEKLATALPSLSSL-TTLSLYNNSICDFGAENLAKVLPAMASLRVLDIQYNKITDVGAQQLtDSLRKC 1079
Cdd:cd00116 226 LNLGDNNLTDAGAAALASALLSPNISlLTLSLSCNDITDDGAKDLAEVLAEKESLLELDLRGNKFGEEGAQLL-AESLLE 304
|
330
....*....|....
gi 2024357723 1080 PHIKNLVMWNPTIP 1093
Cdd:cd00116 305 PGNELESLWVKDDS 318
|
|
| NACHT |
pfam05729 |
NACHT domain; This NTPase domain is found in apoptosis proteins as well as those involved in ... |
379-547 |
3.76e-32 |
|
NACHT domain; This NTPase domain is found in apoptosis proteins as well as those involved in MHC transcription activation. This family is closely related to pfam00931.
Pssm-ID: 428606 [Multi-domain] Cd Length: 166 Bit Score: 123.18 E-value: 3.76e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024357723 379 VIVVLGKAGMGKSVLVQKICQDWSNGE-FSQFEFVFWFDCKQISLPEKWYSLKDLLLDFFVRPQEGSKEIFEYILQNSTK 457
Cdd:pfam05729 2 TVILQGEAGSGKTTLLQKLALLWAQGKlPQGFDFVFFLPCRELSRSGNARSLADLLFSQWPEPAAPVSEVWAVILELPER 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024357723 458 VLLVFDGLEGLhghenspqCSASQPNKDLCRVKELLSGLIQKKILNGCTLLLTARTK--EKVCQYVSKVDkTIEIVGFSP 535
Cdd:pfam05729 82 LLLILDGLDEL--------VSDLGQLDGPCPVLTLLSSLLRKKLLPGASLLLTVRPDalRDLRRGLEEPR-YLEVRGFSE 152
|
170
....*....|..
gi 2024357723 536 WQRELYISKYFE 547
Cdd:pfam05729 153 SDRKQYVRKYFS 164
|
|
| RNA1 |
COG5238 |
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ... |
869-1085 |
4.08e-21 |
|
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];
Pssm-ID: 444072 [Multi-domain] Cd Length: 434 Bit Score: 97.55 E-value: 4.08e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024357723 869 IRLWKYLEQTKDYELLRV-----STEKFVLDPFKAKTMRDIIDLSDlvemqeiiiNRVQDDsGCSSY--QIPAIKNLRKL 941
Cdd:COG5238 144 IQVLKDPLGGNAVHLLGLaarlgLLAAISMAKALQNNSVETVYLGC---------NQIGDE-GIEELaeALTQNTTVTTL 213
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024357723 942 EFALGPAcGLQGFLKLVEILAAFPSLQHLDLdalSENGIGDEGAKSLSEVFPTLTSLETLNLSQNKITDVGAEKLATALP 1021
Cdd:COG5238 214 WLKRNPI-GDEGAEILAEALKGNKSLTTLDL---SNNQIGDEGVIALAEALKNNTTVETLYLSGNQIGAEGAIALAKALQ 289
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2024357723 1022 SLSSLTTLSLYNNSICDFGAENLAKVLPAMASLRVLDIQYNKITDVGAQQLTDSLRKCPHIKNL 1085
Cdd:COG5238 290 GNTTLTSLDLSVNRIGDEGAIALAEGLQGNKTLHTLNLAYNGIGAQGAIALAKALQENTTLHSL 353
|
|
| NACHT |
COG5635 |
Predicted NTPase, NACHT family domain [Signal transduction mechanisms]; |
359-911 |
7.55e-21 |
|
Predicted NTPase, NACHT family domain [Signal transduction mechanisms];
Pssm-ID: 444362 [Multi-domain] Cd Length: 935 Bit Score: 99.11 E-value: 7.55e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024357723 359 AVIERSQIFQMPGGKELETKVIVVLGKAGMGKSVLVQKICQDWSNGEFSQFEFV-FWFDCKQISlpeKWYSLKDLLLDFF 437
Cdd:COG5635 162 NLLERIESLKRLELLEAKKKRLLILGEPGSGKTTLLRYLALELAERYLDAEDPIpILIELRDLA---EEASLEDLLAEAL 238
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024357723 438 VRPQEGSKEIFEYILQNStKVLLVFDGL-EGLHGHENSpqcsasqpnkdlcRVKELLSGLIQKkiLNGCTLLLTARTKEk 516
Cdd:COG5635 239 EKRGGEPEDALERLLRNG-RLLLLLDGLdEVPDEADRD-------------EVLNQLRRFLER--YPKARVIITSRPEG- 301
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024357723 517 vcqYVSKVD---KTIEIVGFSPWQRELYISKYFEGLPSC-DNALNLIKEHEYLFSHCYSPVMCRFVCFLCETilemgDQG 592
Cdd:COG5635 302 ---YDSSELegfEVLELAPLSDEQIEEFLKKWFEATERKaERLLEALEENPELRELARNPLLLTLLALLLRE-----RGE 373
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024357723 593 LPSTLTTLFLKFVQQKI-----MPTQTDVTDVTLAQNQENLATLACIAWYLGEKHLSA------MKSDLLPSKEVKEF-- 659
Cdd:COG5635 374 LPDTRAELYEQFVELLLerwdeQRGLTIYRELSREELRELLSELALAMQENGRTEFAReeleeiLREYLGRRKDAEALld 453
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024357723 660 --ALKNGFFLPfafpkhsdTGEEEYGtmFSDFVIQNFLGALHLI-LTEGIKNKSLIKYLSFPSkkkkpynWlHFVPRFLA 736
Cdd:COG5635 454 elLLRTGLLVE--------RGEGRYS--FAHRSFQEYLAARALVeELDEELLELLAEHLEDPR-------W-REVLLLLA 515
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024357723 737 GLlfLQDDTYFCSLSNKGVKKSTKKQKMLLKYIKRLQIDNLCPERLLEL-LHCIYETQNSYLLQHVALRLKPDLSFLGIV 815
Cdd:COG5635 516 GL--LDDVKQIKELIDALLARDDAAALALAAALLLALLLALALLALLALlLLLRLLLALLALLLLALLLLLLLALLLALL 593
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024357723 816 LTPPDVHVLSSTLKRSRKEFSLDLQNSSIDTHGLKDLVGLKNVVSFRASLSDTIRLWKYLEQTKDYELLRVSTEKFVLDP 895
Cdd:COG5635 594 ALDLGLAALLLLLLLLLLLLLLLALALLLALLLLLLLLLLAELLLLALLALVLLSLLLASRLLLITLLLLAAASAALLLL 673
|
570
....*....|....*.
gi 2024357723 896 FKAKTMRDIIDLSDLV 911
Cdd:COG5635 674 LLLLLAELLLALLALA 689
|
|
| RNA1 |
COG5238 |
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ... |
950-1078 |
2.38e-19 |
|
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];
Pssm-ID: 444072 [Multi-domain] Cd Length: 434 Bit Score: 92.16 E-value: 2.38e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024357723 950 GLQGFLKLVEILAAFPSLQHLDLdalSENGIGDEGAKSLSEVFPTLTSLETLNLSQNKITDVGAEKLATALPSLSSLTTL 1029
Cdd:COG5238 277 GAEGAIALAKALQGNTTLTSLDL---SVNRIGDEGAIALAEGLQGNKTLHTLNLAYNGIGAQGAIALAKALQENTTLHSL 353
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 2024357723 1030 SLYNNSICDFGAENLAKVLPAMASLRVLDIQYNKITDVGAQQLTDSLRK 1078
Cdd:COG5238 354 DLSDNQIGDEGAIALAKYLEGNTTLRELNLGKNNIGKQGAEALIDALQT 402
|
|
| RNA1 |
COG5238 |
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ... |
930-1102 |
1.79e-14 |
|
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];
Pssm-ID: 444072 [Multi-domain] Cd Length: 434 Bit Score: 77.14 E-value: 1.79e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024357723 930 YQIPAIKNLRKLEFALG-PACGLQGFLKLVEILAAF-----PSLQHLDLDALSENGIGDEGAKSLSEVFPTLTSLETLNL 1003
Cdd:COG5238 136 ALPRRINLIQVLKDPLGgNAVHLLGLAARLGLLAAIsmakaLQNNSVETVYLGCNQIGDEGIEELAEALTQNTTVTTLWL 215
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024357723 1004 SQNKITDVGAEKLATALPSLSSLTTLSLYNNSICDFGAENLAKVLPAMASLRVLDIQYNKITDVGAQQLTDSLRKCPHIK 1083
Cdd:COG5238 216 KRNPIGDEGAEILAEALKGNKSLTTLDLSNNQIGDEGVIALAEALKNNTTVETLYLSGNQIGAEGAIALAKALQGNTTLT 295
|
170 180
....*....|....*....|...
gi 2024357723 1084 NLVMW-NPTIPYGVL---EHLQQ 1102
Cdd:COG5238 296 SLDLSvNRIGDEGAIalaEGLQG 318
|
|
| NLRC4_HD2 |
pfam17776 |
NLRC4 helical domain HD2; This entry represents a helical domain found in the NLRC4 protein ... |
691-800 |
4.59e-11 |
|
NLRC4 helical domain HD2; This entry represents a helical domain found in the NLRC4 protein and NOD2 protein.
Pssm-ID: 465499 [Multi-domain] Cd Length: 122 Bit Score: 61.15 E-value: 4.59e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024357723 691 IQNFLGALHLILTEGIKNKSLIKyLSFPSKKKKPY-------------NWLHFVpRFLAGLL------FLQDdTYFCSLS 751
Cdd:pfam17776 4 FQEFFAALFYVLSFKEEKSNPLK-EFFGLRKRESLkslldkalkskngHLDLFL-RFLFGLLneenqrLLEG-LLGCKLS 80
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 2024357723 752 nkgvkkSTKKQKmLLKYIKRLQIDNLCPERLLELLHCIYETQNSYLLQH 800
Cdd:pfam17776 81 ------SEIKQE-LLQWIKSLIQKELSSERFLNLFHCLYELQDESFVKE 122
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
957-1104 |
1.81e-09 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 61.10 E-value: 1.81e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2024357723 957 LVEILAAFPSLQHLDLdalSENGIgdegaKSLSEVFPTLTSLETLNLSQNKITDVGAE--KLaTALpslsslTTLSLYNN 1034
Cdd:COG4886 128 LPEELANLTNLKELDL---SNNQL-----TDLPEPLGNLTNLKSLDLSNNQLTDLPEElgNL-TNL------KELDLSNN 192
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 2024357723 1035 SIcdfgaENLAKVLPAMASLRVLDIQYNKITDvgaqqLTDSLRKCPHIKNLVMWN---PTIPY-GVLEHLQQLD 1104
Cdd:COG4886 193 QI-----TDLPEPLGNLTNLEELDLSGNQLTD-----LPEPLANLTNLETLDLSNnqlTDLPElGNLTNLEELD 256
|
|
| LRR_6 |
pfam13516 |
Leucine Rich repeat; |
994-1017 |
6.74e-04 |
|
Leucine Rich repeat;
Pssm-ID: 463907 [Multi-domain] Cd Length: 24 Bit Score: 37.99 E-value: 6.74e-04
|
| LRR_RI |
smart00368 |
Leucine rich repeat, ribonuclease inhibitor type; |
995-1020 |
1.13e-03 |
|
Leucine rich repeat, ribonuclease inhibitor type;
Pssm-ID: 197686 [Multi-domain] Cd Length: 28 Bit Score: 37.39 E-value: 1.13e-03
|
| LRR_RI |
smart00368 |
Leucine rich repeat, ribonuclease inhibitor type; |
1051-1077 |
5.06e-03 |
|
Leucine rich repeat, ribonuclease inhibitor type;
Pssm-ID: 197686 [Multi-domain] Cd Length: 28 Bit Score: 35.46 E-value: 5.06e-03
|
| |
