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Conserved domains on  [gi|73979397|ref|XP_848261|]
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macrophage scavenger receptor types I and II isoform X1 [Canis lupus familiaris]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SR smart00202
Scavenger receptor Cys-rich; The sea urchin egg peptide speract contains 4 repeats of SR ...
 353-453 3.16e-50

Scavenger receptor Cys-rich; The sea urchin egg peptide speract contains 4 repeats of SR domains that contain 6 conserved cysteines. May bind bacterial antigens in the protein MARCO.


:

Pssm-ID: 214555 [Multi-domain]  Cd Length: 101  Bit Score: 165.59  E-value: 3.16e-50
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 73979397    353 VRLVGGKAPHEGRVEIFHNGQWGTVCDDHWELRGGQVICRSLGYQGVQTVHKGAYFGQGTGPIWLNEVFCFGRESSIEEC 432
Cdd:smart00202   1 VRLVGGGSPCEGRVEVYHNGQWGTVCDDGWDLRDANVVCRQLGFGGAVSASGSAYFGPGSGPIWLDNVRCSGTEASLSDC 80

                           90       100
                   ....*....|....*....|.
gi 73979397    433 KIRQWGVRVCSHAEDAGVTCT 453
Cdd:smart00202  81 PHSGWGSHNCSHGEDAGVVCS 101
Macscav_rec pfam03523
Macrophage scavenger receptor;
121-169 7.54e-31

Macrophage scavenger receptor;


:

Pssm-ID: 460956  Cd Length: 49  Bit Score: 112.93  E-value: 7.54e-31
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 73979397   121 MEKRIQYISDTEANLIDSEHFQNFSLVTDQRFNDVLLQLSTLVSSVRGH 169
Cdd:pfam03523   1 MEKRIQYISDSEANLIDSEHFQNFSMTTDQRFNDVLLQLNTLVSSVQEH 49
Collagen pfam01391
Collagen triple helix repeat (20 copies); Members of this family belong to the collagen ...
 280-337 4.69e-19

Collagen triple helix repeat (20 copies); Members of this family belong to the collagen superfamily. Collagens are generally extracellular structural proteins involved in formation of connective tissue structure. The alignment contains 20 copies of the G-X-Y repeat that forms a triple helix. The first position of the repeat is glycine, the second and third positions can be any residue but are frequently proline and hydroxy-proline. Collagens are post translationally modified by proline hydroxylase to form the hydroxy-proline residues. Defective hydroxylation is the cause of scurvy. Some members of the collagen superfamily are not involved in connective tissue structure but share the same triple helical structure. The family includes bacterial collagen-like triple-helix repeat proteins.


:

Pssm-ID: 460189 [Multi-domain]  Cd Length: 57  Bit Score: 80.62  E-value: 4.69e-19
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 73979397   280 EKGDRGPTGESGPRGVPGAIGPPGLKGDRGAIGFPGARGFPGPvgkTGRTGNPGPKGQ 337
Cdd:pfam01391   2 PPGPPGPPGPPGPPGPPGPPGPPGPPGPPGEPGPPGPPGPPGP---PGPPGAPGAPGP 56
gly_rich_SclB super family cl45768
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 196-342 4.25e-12

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


The actual alignment was detected with superfamily member NF038329:

Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 67.62  E-value: 4.25e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 73979397  196 TLNDKVQDNTFKQQEDMSRLEERLYNASAEIMSMKEKQVNLEQEIKGEVKLLNNITNDLrlkdweHSQTLKNITLIQGPP 275
Cdd:NF038329  52 ATIETQQRKLQELREAFPRLEEIYKSTPLDDTTVNKIYKYLEERDKKLNSYLEELDEGL------QQLKGDGEKGEPGPA 125

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 73979397  276 GPPGEKGDRGPTGESGPRGVPGAIGPPGLKGDRGAIGFPGARGFPGPVGKTGRTGNPGPKGQKGDKG 342
Cdd:NF038329 126 GPAGPAGEQGPRGDRGETGPAGPAGPPGPQGERGEKGPAGPQGEAGPQGPAGKDGEAGAKGPAGEKG 192
 
Name Accession Description Interval E-value
SR smart00202
Scavenger receptor Cys-rich; The sea urchin egg peptide speract contains 4 repeats of SR ...
 353-453 3.16e-50

Scavenger receptor Cys-rich; The sea urchin egg peptide speract contains 4 repeats of SR domains that contain 6 conserved cysteines. May bind bacterial antigens in the protein MARCO.


Pssm-ID: 214555 [Multi-domain]  Cd Length: 101  Bit Score: 165.59  E-value: 3.16e-50
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 73979397    353 VRLVGGKAPHEGRVEIFHNGQWGTVCDDHWELRGGQVICRSLGYQGVQTVHKGAYFGQGTGPIWLNEVFCFGRESSIEEC 432
Cdd:smart00202   1 VRLVGGGSPCEGRVEVYHNGQWGTVCDDGWDLRDANVVCRQLGFGGAVSASGSAYFGPGSGPIWLDNVRCSGTEASLSDC 80

                           90       100
                   ....*....|....*....|.
gi 73979397    433 KIRQWGVRVCSHAEDAGVTCT 453
Cdd:smart00202  81 PHSGWGSHNCSHGEDAGVVCS 101
SRCR pfam00530
Scavenger receptor cysteine-rich domain; These domains are disulphide rich extracellular ...
 358-453 1.12e-44

Scavenger receptor cysteine-rich domain; These domains are disulphide rich extracellular domains. These domains are found in several extracellular receptors and may be involved in protein-protein interactions.


Pssm-ID: 459844  Cd Length: 98  Bit Score: 150.99  E-value: 1.12e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 73979397   358 GKAPHEGRVEIFHNGQWGTVCDDHWELRGGQVICRSLGY-QGVQTVHKGAYFGQG-TGPIWLNEVFCFGRESSIEECKIR 435
Cdd:pfam00530   1 GSSPCEGRVEVYHNGSWGTVCDDGWDLRDAHVVCRQLGCgGAVSAPSGCSYFGPGsTGPIWLDDVRCSGNETSLWQCPHR 80

                          90
                  ....*....|....*...
gi 73979397   436 QWGVRVCSHAEDAGVTCT 453
Cdd:pfam00530  81 PWGNHNCSHSEDAGVICS 98
Macscav_rec pfam03523
Macrophage scavenger receptor;
121-169 7.54e-31

Macrophage scavenger receptor;


Pssm-ID: 460956  Cd Length: 49  Bit Score: 112.93  E-value: 7.54e-31
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 73979397   121 MEKRIQYISDTEANLIDSEHFQNFSLVTDQRFNDVLLQLSTLVSSVRGH 169
Cdd:pfam03523   1 MEKRIQYISDSEANLIDSEHFQNFSMTTDQRFNDVLLQLNTLVSSVQEH 49
Collagen pfam01391
Collagen triple helix repeat (20 copies); Members of this family belong to the collagen ...
 280-337 4.69e-19

Collagen triple helix repeat (20 copies); Members of this family belong to the collagen superfamily. Collagens are generally extracellular structural proteins involved in formation of connective tissue structure. The alignment contains 20 copies of the G-X-Y repeat that forms a triple helix. The first position of the repeat is glycine, the second and third positions can be any residue but are frequently proline and hydroxy-proline. Collagens are post translationally modified by proline hydroxylase to form the hydroxy-proline residues. Defective hydroxylation is the cause of scurvy. Some members of the collagen superfamily are not involved in connective tissue structure but share the same triple helical structure. The family includes bacterial collagen-like triple-helix repeat proteins.


Pssm-ID: 460189 [Multi-domain]  Cd Length: 57  Bit Score: 80.62  E-value: 4.69e-19
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 73979397   280 EKGDRGPTGESGPRGVPGAIGPPGLKGDRGAIGFPGARGFPGPvgkTGRTGNPGPKGQ 337
Cdd:pfam01391   2 PPGPPGPPGPPGPPGPPGPPGPPGPPGPPGEPGPPGPPGPPGP---PGPPGAPGAPGP 56
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 280-342 4.10e-12

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 67.62  E-value: 4.10e-12
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 73979397  280 EKGDRGPTGESGPRGVPGAIGPPGLKGDRGAIGFPGARGFPGPVGKTGRTGNPGPKGQKGDKG 342
Cdd:NF038329 166 PQGEAGPQGPAGKDGEAGAKGPAGEKGPQGPRGETGPAGEQGPAGPAGPDGEAGPAGEDGPAG 228
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 196-342 4.25e-12

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 67.62  E-value: 4.25e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 73979397  196 TLNDKVQDNTFKQQEDMSRLEERLYNASAEIMSMKEKQVNLEQEIKGEVKLLNNITNDLrlkdweHSQTLKNITLIQGPP 275
Cdd:NF038329  52 ATIETQQRKLQELREAFPRLEEIYKSTPLDDTTVNKIYKYLEERDKKLNSYLEELDEGL------QQLKGDGEKGEPGPA 125

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 73979397  276 GPPGEKGDRGPTGESGPRGVPGAIGPPGLKGDRGAIGFPGARGFPGPVGKTGRTGNPGPKGQKGDKG 342
Cdd:NF038329 126 GPAGPAGEQGPRGDRGETGPAGPAGPPGPQGERGEKGPAGPQGEAGPQGPAGKDGEAGAKGPAGEKG 192
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 281-344 4.69e-11

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 64.54  E-value: 4.69e-11
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 73979397  281 KGDRGPTGESGPRGVPGAIGPPGLKGDRGAIGFPGARGFPGPVGKTGRTGNPGPKGQKGDKGSG 344
Cdd:NF038329 173 QGPAGKDGEAGAKGPAGEKGPQGPRGETGPAGEQGPAGPAGPDGEAGPAGEDGPAGPAGDGQQG 236
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 278-342 1.37e-09

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 59.92  E-value: 1.37e-09
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 73979397  278 PGEKGDRGPTGESGPRGVPGAIGPPGLKGDRGAIGFPGARGFPGPVGKTGRTGNPG--PKGQKGDKG 342
Cdd:NF038329 176 AGKDGEAGAKGPAGEKGPQGPRGETGPAGEQGPAGPAGPDGEAGPAGEDGPAGPAGdgQQGPDGDPG 242
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 279-342 1.37e-09

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 59.92  E-value: 1.37e-09
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 73979397  279 GEKGDRGPTGESGPRGVPGAIGPPGLKGDRGAigfPGARGFPGPVGKTGRTGNPGPKGQKGDKG 342
Cdd:NF038329 260 GPRGDRGEAGPDGPDGKDGERGPVGPAGKDGQ---NGKDGLPGKDGKDGQNGKDGLPGKDGKDG 320
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 279-349 1.90e-08

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 56.45  E-value: 1.90e-08
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 73979397  279 GEKGDRGPTGESGPRGVPGAIGPPGLKGDRGAIGFPGARGFPGPVGKTGRTGNPGPKG----QKGDKGSGSMLTP 349
Cdd:NF038329 287 GKDGQNGKDGLPGKDGKDGQNGKDGLPGKDGKDGQPGKDGLPGKDGKDGQPGKPAPKTpevpQKPDTAPHTPKTP 361
SPT5 COG5164
Transcription elongation factor SPT5 [Transcription];
282-361 6.93e-05

Transcription elongation factor SPT5 [Transcription];


Pssm-ID: 444063 [Multi-domain]  Cd Length: 495  Bit Score: 45.02  E-value: 6.93e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 73979397 282 GDRGPTGESGPRGVPGAIGPPglkGDRGAIGFPGARGFPGPVGKTGRTGNPGPKGQKGDKGSGSMLTPFktvrlVGGKAP 361
Cdd:COG5164  73 GPAQNQGGTTPAQNQGGTRPA---GNTGGTTPAGDGGATGPPDDGGATGPPDDGGSTTPPSGGSTTPPG-----DGGSTP 144
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 173-241 5.76e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 38.37  E-value: 5.76e-03
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 73979397 173 IDEISKSLINLNTTLLDLQLNIKTLNDKVQDNTFKQQEDMSRLEE----RLYNA-SAEIMSMKEKQVNLEQEIK 241
Cdd:COG1579  40 LAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNvrnnKEYEAlQKEIESLKRRISDLEDEIL 113
 
Name Accession Description Interval E-value
SR smart00202
Scavenger receptor Cys-rich; The sea urchin egg peptide speract contains 4 repeats of SR ...
 353-453 3.16e-50

Scavenger receptor Cys-rich; The sea urchin egg peptide speract contains 4 repeats of SR domains that contain 6 conserved cysteines. May bind bacterial antigens in the protein MARCO.


Pssm-ID: 214555 [Multi-domain]  Cd Length: 101  Bit Score: 165.59  E-value: 3.16e-50
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 73979397    353 VRLVGGKAPHEGRVEIFHNGQWGTVCDDHWELRGGQVICRSLGYQGVQTVHKGAYFGQGTGPIWLNEVFCFGRESSIEEC 432
Cdd:smart00202   1 VRLVGGGSPCEGRVEVYHNGQWGTVCDDGWDLRDANVVCRQLGFGGAVSASGSAYFGPGSGPIWLDNVRCSGTEASLSDC 80

                           90       100
                   ....*....|....*....|.
gi 73979397    433 KIRQWGVRVCSHAEDAGVTCT 453
Cdd:smart00202  81 PHSGWGSHNCSHGEDAGVVCS 101
SRCR pfam00530
Scavenger receptor cysteine-rich domain; These domains are disulphide rich extracellular ...
 358-453 1.12e-44

Scavenger receptor cysteine-rich domain; These domains are disulphide rich extracellular domains. These domains are found in several extracellular receptors and may be involved in protein-protein interactions.


Pssm-ID: 459844  Cd Length: 98  Bit Score: 150.99  E-value: 1.12e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 73979397   358 GKAPHEGRVEIFHNGQWGTVCDDHWELRGGQVICRSLGY-QGVQTVHKGAYFGQG-TGPIWLNEVFCFGRESSIEECKIR 435
Cdd:pfam00530   1 GSSPCEGRVEVYHNGSWGTVCDDGWDLRDAHVVCRQLGCgGAVSAPSGCSYFGPGsTGPIWLDDVRCSGNETSLWQCPHR 80

                          90
                  ....*....|....*...
gi 73979397   436 QWGVRVCSHAEDAGVTCT 453
Cdd:pfam00530  81 PWGNHNCSHSEDAGVICS 98
Macscav_rec pfam03523
Macrophage scavenger receptor;
121-169 7.54e-31

Macrophage scavenger receptor;


Pssm-ID: 460956  Cd Length: 49  Bit Score: 112.93  E-value: 7.54e-31
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 73979397   121 MEKRIQYISDTEANLIDSEHFQNFSLVTDQRFNDVLLQLSTLVSSVRGH 169
Cdd:pfam03523   1 MEKRIQYISDSEANLIDSEHFQNFSMTTDQRFNDVLLQLNTLVSSVQEH 49
Collagen pfam01391
Collagen triple helix repeat (20 copies); Members of this family belong to the collagen ...
 280-337 4.69e-19

Collagen triple helix repeat (20 copies); Members of this family belong to the collagen superfamily. Collagens are generally extracellular structural proteins involved in formation of connective tissue structure. The alignment contains 20 copies of the G-X-Y repeat that forms a triple helix. The first position of the repeat is glycine, the second and third positions can be any residue but are frequently proline and hydroxy-proline. Collagens are post translationally modified by proline hydroxylase to form the hydroxy-proline residues. Defective hydroxylation is the cause of scurvy. Some members of the collagen superfamily are not involved in connective tissue structure but share the same triple helical structure. The family includes bacterial collagen-like triple-helix repeat proteins.


Pssm-ID: 460189 [Multi-domain]  Cd Length: 57  Bit Score: 80.62  E-value: 4.69e-19
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 73979397   280 EKGDRGPTGESGPRGVPGAIGPPGLKGDRGAIGFPGARGFPGPvgkTGRTGNPGPKGQ 337
Cdd:pfam01391   2 PPGPPGPPGPPGPPGPPGPPGPPGPPGPPGEPGPPGPPGPPGP---PGPPGAPGAPGP 56
Collagen pfam01391
Collagen triple helix repeat (20 copies); Members of this family belong to the collagen ...
 294-342 4.04e-13

Collagen triple helix repeat (20 copies); Members of this family belong to the collagen superfamily. Collagens are generally extracellular structural proteins involved in formation of connective tissue structure. The alignment contains 20 copies of the G-X-Y repeat that forms a triple helix. The first position of the repeat is glycine, the second and third positions can be any residue but are frequently proline and hydroxy-proline. Collagens are post translationally modified by proline hydroxylase to form the hydroxy-proline residues. Defective hydroxylation is the cause of scurvy. Some members of the collagen superfamily are not involved in connective tissue structure but share the same triple helical structure. The family includes bacterial collagen-like triple-helix repeat proteins.


Pssm-ID: 460189 [Multi-domain]  Cd Length: 57  Bit Score: 63.67  E-value: 4.04e-13
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 73979397   294 GVPGAIGPPGLKGDRGA---IGFP---GARGFPGPVGKTGRTGNPGPKGQKGDKG 342
Cdd:pfam01391   1 GPPGPPGPPGPPGPPGPpgpPGPPgppGPPGEPGPPGPPGPPGPPGPPGAPGAPG 55
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 280-342 4.10e-12

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 67.62  E-value: 4.10e-12
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 73979397  280 EKGDRGPTGESGPRGVPGAIGPPGLKGDRGAIGFPGARGFPGPVGKTGRTGNPGPKGQKGDKG 342
Cdd:NF038329 166 PQGEAGPQGPAGKDGEAGAKGPAGEKGPQGPRGETGPAGEQGPAGPAGPDGEAGPAGEDGPAG 228
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 196-342 4.25e-12

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 67.62  E-value: 4.25e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 73979397  196 TLNDKVQDNTFKQQEDMSRLEERLYNASAEIMSMKEKQVNLEQEIKGEVKLLNNITNDLrlkdweHSQTLKNITLIQGPP 275
Cdd:NF038329  52 ATIETQQRKLQELREAFPRLEEIYKSTPLDDTTVNKIYKYLEERDKKLNSYLEELDEGL------QQLKGDGEKGEPGPA 125

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 73979397  276 GPPGEKGDRGPTGESGPRGVPGAIGPPGLKGDRGAIGFPGARGFPGPVGKTGRTGNPGPKGQKGDKG 342
Cdd:NF038329 126 GPAGPAGEQGPRGDRGETGPAGPAGPPGPQGERGEKGPAGPQGEAGPQGPAGKDGEAGAKGPAGEKG 192
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 281-344 4.69e-11

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 64.54  E-value: 4.69e-11
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 73979397  281 KGDRGPTGESGPRGVPGAIGPPGLKGDRGAIGFPGARGFPGPVGKTGRTGNPGPKGQKGDKGSG 344
Cdd:NF038329 173 QGPAGKDGEAGAKGPAGEKGPQGPRGETGPAGEQGPAGPAGPDGEAGPAGEDGPAGPAGDGQQG 236
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 278-342 1.37e-09

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 59.92  E-value: 1.37e-09
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 73979397  278 PGEKGDRGPTGESGPRGVPGAIGPPGLKGDRGAIGFPGARGFPGPVGKTGRTGNPG--PKGQKGDKG 342
Cdd:NF038329 176 AGKDGEAGAKGPAGEKGPQGPRGETGPAGEQGPAGPAGPDGEAGPAGEDGPAGPAGdgQQGPDGDPG 242
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 279-342 1.37e-09

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 59.92  E-value: 1.37e-09
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 73979397  279 GEKGDRGPTGESGPRGVPGAIGPPGLKGDRGAigfPGARGFPGPVGKTGRTGNPGPKGQKGDKG 342
Cdd:NF038329 260 GPRGDRGEAGPDGPDGKDGERGPVGPAGKDGQ---NGKDGLPGKDGKDGQNGKDGLPGKDGKDG 320
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 279-349 1.90e-08

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 56.45  E-value: 1.90e-08
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 73979397  279 GEKGDRGPTGESGPRGVPGAIGPPGLKGDRGAIGFPGARGFPGPVGKTGRTGNPGPKG----QKGDKGSGSMLTP 349
Cdd:NF038329 287 GKDGQNGKDGLPGKDGKDGQNGKDGLPGKDGKDGQPGKDGLPGKDGKDGQPGKPAPKTpevpQKPDTAPHTPKTP 361
Collagen pfam01391
Collagen triple helix repeat (20 copies); Members of this family belong to the collagen ...
 284-317 2.90e-08

Collagen triple helix repeat (20 copies); Members of this family belong to the collagen superfamily. Collagens are generally extracellular structural proteins involved in formation of connective tissue structure. The alignment contains 20 copies of the G-X-Y repeat that forms a triple helix. The first position of the repeat is glycine, the second and third positions can be any residue but are frequently proline and hydroxy-proline. Collagens are post translationally modified by proline hydroxylase to form the hydroxy-proline residues. Defective hydroxylation is the cause of scurvy. Some members of the collagen superfamily are not involved in connective tissue structure but share the same triple helical structure. The family includes bacterial collagen-like triple-helix repeat proteins.


Pssm-ID: 460189 [Multi-domain]  Cd Length: 57  Bit Score: 49.80  E-value: 2.90e-08
                          10        20        30
                  ....*....|....*....|....*....|....
gi 73979397   284 RGPTGESGPRGVPGAIGPPGLKGDRGAIGFPGAR 317
Cdd:pfam01391  24 PGPPGPPGEPGPPGPPGPPGPPGPPGAPGAPGPP 57
Collagen pfam01391
Collagen triple helix repeat (20 copies); Members of this family belong to the collagen ...
 309-343 8.90e-06

Collagen triple helix repeat (20 copies); Members of this family belong to the collagen superfamily. Collagens are generally extracellular structural proteins involved in formation of connective tissue structure. The alignment contains 20 copies of the G-X-Y repeat that forms a triple helix. The first position of the repeat is glycine, the second and third positions can be any residue but are frequently proline and hydroxy-proline. Collagens are post translationally modified by proline hydroxylase to form the hydroxy-proline residues. Defective hydroxylation is the cause of scurvy. Some members of the collagen superfamily are not involved in connective tissue structure but share the same triple helical structure. The family includes bacterial collagen-like triple-helix repeat proteins.


Pssm-ID: 460189 [Multi-domain]  Cd Length: 57  Bit Score: 42.87  E-value: 8.90e-06
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 73979397   309 GAIGFPGARGFPGPVGKTGRTGNPGPKGQKGDKGS 343
Cdd:pfam01391   1 GPPGPPGPPGPPGPPGPPGPPGPPGPPGPPGEPGP 35
SPT5 COG5164
Transcription elongation factor SPT5 [Transcription];
282-361 6.93e-05

Transcription elongation factor SPT5 [Transcription];


Pssm-ID: 444063 [Multi-domain]  Cd Length: 495  Bit Score: 45.02  E-value: 6.93e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 73979397 282 GDRGPTGESGPRGVPGAIGPPglkGDRGAIGFPGARGFPGPVGKTGRTGNPGPKGQKGDKGSGSMLTPFktvrlVGGKAP 361
Cdd:COG5164  73 GPAQNQGGTTPAQNQGGTRPA---GNTGGTTPAGDGGATGPPDDGGATGPPDDGGSTTPPSGGSTTPPG-----DGGSTP 144
SPT5 COG5164
Transcription elongation factor SPT5 [Transcription];
279-361 3.07e-04

Transcription elongation factor SPT5 [Transcription];


Pssm-ID: 444063 [Multi-domain]  Cd Length: 495  Bit Score: 43.09  E-value: 3.07e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 73979397 279 GEKGDRGPTGESGPRGVPGAIGPPglkGDRGAIGFPGARGFPGPVGKTGRTGNPGPKGQKGDKGSGSMLTPFKTvrlVGG 358
Cdd:COG5164  16 GVTTPAGSQGSTKPAQNQGSTRPA---GNTGGTRPAQNQGSTTPAGNTGGTRPAGNQGATGPAQNQGGTTPAQN---QGG 89


                ...
gi 73979397 359 KAP 361
Cdd:COG5164  90 TRP 92
SPT5 COG5164
Transcription elongation factor SPT5 [Transcription];
285-366 3.44e-04

Transcription elongation factor SPT5 [Transcription];


Pssm-ID: 444063 [Multi-domain]  Cd Length: 495  Bit Score: 43.09  E-value: 3.44e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 73979397 285 GPTGESGPRGVPGAIGPPglkgDRGAIGFPGARGFPGPVGKTGRTGNPGPKGQKGDKGSGSMLTPFKTVRLVGGKAPHEG 364
Cdd:COG5164 169 GPGGSTTPPDDGGSTTPP----NKGETGTDIPTGGTPRQGPDGPVKKDDKNGKGNPPDDRGGKTGPKDQRPKTNPIERRG 244


                ..
gi 73979397 365 RV 366
Cdd:COG5164 245 PE 246
SRCR_2 pfam15494
Scavenger receptor cysteine-rich domain; SRCR_2 is a scavenger receptor cysteine-rich domain ...
 370-405 2.40e-03

Scavenger receptor cysteine-rich domain; SRCR_2 is a scavenger receptor cysteine-rich domain family found largely on vertebrate sequences up-stream of the trypsin-like transmembrane serine protease, Spinesin.


Pssm-ID: 464747  Cd Length: 99  Bit Score: 37.31  E-value: 2.40e-03
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 73979397   370 HNGQWGTVCDDHWELRGGQVICRSLGYQgVQTVHKG 405
Cdd:pfam15494  12 ARPSWLPVCSDDWNPAYGRAACQQLGYL-RLTHHKS 46
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 173-241 5.76e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 38.37  E-value: 5.76e-03
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 73979397 173 IDEISKSLINLNTTLLDLQLNIKTLNDKVQDNTFKQQEDMSRLEE----RLYNA-SAEIMSMKEKQVNLEQEIK 241
Cdd:COG1579  40 LAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLGNvrnnKEYEAlQKEIESLKRRISDLEDEIL 113
SPT5 COG5164
Transcription elongation factor SPT5 [Transcription];
278-349 8.95e-03

Transcription elongation factor SPT5 [Transcription];


Pssm-ID: 444063 [Multi-domain]  Cd Length: 495  Bit Score: 38.47  E-value: 8.95e-03
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 73979397 278 PGEKGDRGPTGESGPRGVPGAIGPPglkGDRGAIGFPGARGFPGPVGKTGRTGNPGPKGQKGDKGSGSMLTP 349
Cdd:COG5164  42 TGGTRPAQNQGSTTPAGNTGGTRPA---GNQGATGPAQNQGGTTPAQNQGGTRPAGNTGGTTPAGDGGATGP 110
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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