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Conserved domains on  [gi|160409925|ref|YP_001551771|]
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membrane protein E3 RID-beta [Human mastadenovirus C]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Adeno_E3_14_5 pfam04834
Early E3 14.5 kDa protein; The E3B 14.5 kDa was first identified in Human adenovirus type 5. ...
 31-130 2.70e-45

Early E3 14.5 kDa protein; The E3B 14.5 kDa was first identified in Human adenovirus type 5. It is an integral membrane protein oriented with its C terminus in the cytoplasm. It functions to down-regulate the epidermal growth factor receptor and prevent tumour necrosis factor cytolysis. It achieves this through the interaction with E3 10.4 kDa protein.


:

Pssm-ID: 461451  Cd Length: 100  Bit Score: 142.52  E-value: 2.70e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 160409925   31 SCRFTQIWNIPSCYNKQSDLSEAWLYAIISVMVFCSTIFALAIYPYLDIGWNAIDAMNHPTFPVPAVIPLQQVIAPINQP 110
Cdd:pfam04834   1 MCRFTIFVLIIFCALKQLCLQEAALPAIHISCRFCQIIFALACYNKLDDGSEAIDAAIHPTFPFCATIFALAIIAPIDIG 80

                          90       100
                  ....*....|....*....|
gi 160409925  111 RPPSPTPTEISYFNLTGGDD 130
Cdd:pfam04834  81 RNAIDAMNEISFFNLAGGDD 100
 
Name Accession Description Interval E-value
Adeno_E3_14_5 pfam04834
Early E3 14.5 kDa protein; The E3B 14.5 kDa was first identified in Human adenovirus type 5. ...
 31-130 2.70e-45

Early E3 14.5 kDa protein; The E3B 14.5 kDa was first identified in Human adenovirus type 5. It is an integral membrane protein oriented with its C terminus in the cytoplasm. It functions to down-regulate the epidermal growth factor receptor and prevent tumour necrosis factor cytolysis. It achieves this through the interaction with E3 10.4 kDa protein.


Pssm-ID: 461451  Cd Length: 100  Bit Score: 142.52  E-value: 2.70e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 160409925   31 SCRFTQIWNIPSCYNKQSDLSEAWLYAIISVMVFCSTIFALAIYPYLDIGWNAIDAMNHPTFPVPAVIPLQQVIAPINQP 110
Cdd:pfam04834   1 MCRFTIFVLIIFCALKQLCLQEAALPAIHISCRFCQIIFALACYNKLDDGSEAIDAAIHPTFPFCATIFALAIIAPIDIG 80

                          90       100
                  ....*....|....*....|
gi 160409925  111 RPPSPTPTEISYFNLTGGDD 130
Cdd:pfam04834  81 RNAIDAMNEISFFNLAGGDD 100
 
Name Accession Description Interval E-value
Adeno_E3_14_5 pfam04834
Early E3 14.5 kDa protein; The E3B 14.5 kDa was first identified in Human adenovirus type 5. ...
 31-130 2.70e-45

Early E3 14.5 kDa protein; The E3B 14.5 kDa was first identified in Human adenovirus type 5. It is an integral membrane protein oriented with its C terminus in the cytoplasm. It functions to down-regulate the epidermal growth factor receptor and prevent tumour necrosis factor cytolysis. It achieves this through the interaction with E3 10.4 kDa protein.


Pssm-ID: 461451  Cd Length: 100  Bit Score: 142.52  E-value: 2.70e-45
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 160409925   31 SCRFTQIWNIPSCYNKQSDLSEAWLYAIISVMVFCSTIFALAIYPYLDIGWNAIDAMNHPTFPVPAVIPLQQVIAPINQP 110
Cdd:pfam04834   1 MCRFTIFVLIIFCALKQLCLQEAALPAIHISCRFCQIIFALACYNKLDDGSEAIDAAIHPTFPFCATIFALAIIAPIDIG 80

                          90       100
                  ....*....|....*....|
gi 160409925  111 RPPSPTPTEISYFNLTGGDD 130
Cdd:pfam04834  81 RNAIDAMNEISFFNLAGGDD 100
Adeno_E3_14_5 pfam04834
Early E3 14.5 kDa protein; The E3B 14.5 kDa was first identified in Human adenovirus type 5. ...
 1-100 2.00e-44

Early E3 14.5 kDa protein; The E3B 14.5 kDa was first identified in Human adenovirus type 5. It is an integral membrane protein oriented with its C terminus in the cytoplasm. It functions to down-regulate the epidermal growth factor receptor and prevent tumour necrosis factor cytolysis. It achieves this through the interaction with E3 10.4 kDa protein.


Pssm-ID: 461451  Cd Length: 100  Bit Score: 140.60  E-value: 2.00e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 160409925    1 MKRSVIFVLLIFCALPVLCSQTSAPPKRHISCRFTQIWNIPSCYNKQSDLSEAWLYAIISVMVFCSTIFALAIYPYLDIG 80
Cdd:pfam04834   1 MCRFTIFVLIIFCALKQLCLQEAALPAIHISCRFCQIIFALACYNKLDDGSEAIDAAIHPTFPFCATIFALAIIAPIDIG 80

                          90       100
                  ....*....|....*....|
gi 160409925   81 WNAIDAMNHPTFPVPAVIPL 100
Cdd:pfam04834  81 RNAIDAMNEISFFNLAGGDD 100
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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