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1PJ2:
Crystal structure of human mitochondrial NAD(P)+-dependent malic enzyme in a pentary complex with natural substrate malate, cofactor NADH, Mn++, and allosteric activator fumarate
PDB ID:
1PJ2
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MMDB ID:
25336
PDB Deposition Date:
2003/5/30
Updated in MMDB:
2003/12
Experimental Method:
x-ray diffraction
Resolution:
2.3 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
Download sequence data
Biological Unit for 1PJ2: tetrameric; determined by author and by software (PISA)
Molecular Components in 1PJ2
Label
Count
Molecule
Proteins (4 molecules)
A
B
C
D
4
Nad-dependent Malic Enzyme, Mitochondrial
(Gene symbol:
ME2
)
Chemicals and Non-standard biopolymers (20 molecules)
1
4
(2S)-2-hydroxybutanedioic acid
2
4
MANGANESE (II) ION
3
8
1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE
4
4
FUMARIC ACID
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303