1T3R: HIV protease wild-type in complex with TMC114 inhibitor

PDB ID: 1T3RDownload
MMDB ID: 32736
PDB Deposition Date: 2004/4/27
Updated in MMDB: 2021/11
Experimental Method:
x-ray diffraction
Resolution: 1.2  Å
Source Organism:
Similar Structures:
Biological Unit for 1T3R: dimeric; determined by author and by software (PISA)
Molecular Components in 1T3R
Label Count Molecule
Proteins (2 molecules)
2
Protease Retropepsin
(Gene symbol: gag-pol)
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
5
PHOSPHATE IONPHOSPHATE ION
2
1
(3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE(3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303