1X2R: Structural basis for the defects of human lung cancer somatic mutations in the repression activity of Keap1 on Nrf2

PDB ID: 1X2RDownload
MMDB ID: 37885
PDB Deposition Date: 2005/4/26
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 1.7  Å
Source Organism:
synthetic construct▼
Similar Structures:
Biological Unit for 1X2R: dimeric; determined by author and by software (PISA)
Molecular Components in 1X2R
Label Count Molecule
Proteins (2 molecules)
1
Kelch-like Ech-associated Protein 1
Molecule annotation
1
Nuclear Factor Erythroid 2 Related Factor 2
Molecule annotation
Chemicals and Non-standard biopolymers (9 molecules)
1
9
SULFATE IONSULFATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303