2GMX: Selective Aminopyridine-Based C-Jun N-terminal Kinase inhibitors with cellular activity

PDB ID: 2GMXDownload
MMDB ID: 39389
PDB Deposition Date: 2006/4/7
Updated in MMDB: 2006/12
Experimental Method:
x-ray diffraction
Resolution: 3.5  Å
Source Organism:
synthetic construct▼
Similar Structures:
Biological Unit for 2GMX: dimeric; determined by author and by software (PISA)
Molecular Components in 2GMX
Label Count Molecule
Proteins (2 molecules)
1
Mitogen-activated Protein Kinase 8
Molecule annotation
1
C-jun-amino-terminal Kinase-interacting Protein 1
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
4
SULFATE IONSULFATE ION
2
1
N-(4-AMINO-5-CYANO-6-ETHOXYPYRIDIN-2-YL)-2-(4-BROMO-2,5-DIMETHOXYPHENYL)ACETAMIDEN-(4-AMINO-5-CYANO-6-ETHOXYPYRIDIN-2-YL)-2-(4-BROMO-2,5-DIMETHOXYPHENYL)ACETAMIDE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303