2P5W: Crystal structures of high affinity human T-cell receptors bound to pMHC reveal native diagonal binding geometry

PDB ID: 2P5WDownload
MMDB ID: 59240
PDB Deposition Date: 2007/3/16
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 2.2  Å
Source Organism:
synthetic construct▼
Similar Structures:
Biological Unit for 2P5W: pentameric; determined by author
Molecular Components in 2P5W
Label Count Molecule
Proteins (5 molecules)
1
HLA Class I Histocompatibility Antigen, A-2 Alpha Chain
Molecule annotation
1
Beta-2-microglobulin
Molecule annotation
1
Cancer/testis Antigen 1B
Molecule annotation
1
T-cell Receptor, Alpha Chain
Molecule annotation
1
Hypothetical Protein
Molecule annotation
Chemicals and Non-standard biopolymers (20 molecules)
1
6
SULFATE IONSULFATE ION
2
11
GLYCEROLGLYCEROL
3
1
CALCIUM IONCALCIUM ION
4
1
MAGNESIUM IONMAGNESIUM ION
5
1
4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303