2WTX: Insight into the mechanism of enzymatic glycosyltransfer with retention through the synthesis and analysis of bisubstrate glycomimetics of trehalose-6-phosphate synthase

PDB ID: 2WTXDownload
MMDB ID: 80226
PDB Deposition Date: 2009/9/25
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 2.2  Å
Source Organism:
Similar Structures:
Biological Unit for 2WTX: dimeric; determined by author and by software (PISA)
Molecular Components in 2WTX
Label Count Molecule
Proteins (2 molecules)
2
Alpha, Alpha-trehalose-phosphate Synthase [udp-forming]
(Gene symbol: otsA)
Molecule annotation
Chemicals and Non-standard biopolymers (7 molecules)
1
3
1,2-ETHANEDIOL1,2-ETHANEDIOL
2
2
URIDINE-5'-DIPHOSPHATEURIDINE-5'-DIPHOSPHATE
3
2
[(1R,2R,3S,4S,5S)-2,3,4-TRIHYDROXY-5-{[(1S,4R,5S,6S)-4,5,6-TRIHYDROXY-3-(HYDROXYMETHYL)CYCLOHEX-2-EN-1-YL]AMINO}CYCLOHEXYL]METHYL DIHYDROGEN PHOSPHATE[(1R,2R,3S,4S,5S)-2,3,4-TRIHYDROXY-5-{[(1S,4R,5S,6S)-4,5,6-TRIHYDROXY-3-(HYDROXYMETHYL)CYCLOHEX-2-EN-1-YL]AMINO}CYCLOHEXYL]METHYL DIHYDROGEN PHOSPHATE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303