2Y37: The discovery of novel, potent and highly selective inhibitors of inducible nitric oxide synthase (iNOS)

PDB ID: 2Y37Download
MMDB ID: 89787
PDB Deposition Date: 2010/12/19
Updated in MMDB: 2011/05
Experimental Method:
x-ray diffraction
Resolution: 2.6  Å
Source Organism:
Similar Structures:
Biological Unit for 2Y37: dimeric; determined by author and by software (PISA)
Molecular Components in 2Y37
Label Count Molecule
Proteins (2 molecules)
2
Nitric Oxide Synthase, Inducible
(Gene symbol: Nos2)
Molecule annotation
Chemicals and Non-standard biopolymers (11 molecules)
1
3
SULFATE IONSULFATE ION
2
2
GLYCEROLGLYCEROL
3
2
2-[(1R)-3-amino-1-phenyl-propoxy]-4-chloro-benzonitrile2-[(1R)-3-amino-1-phenyl-propoxy]-4-chloro-benzonitrile
4
2
PROTOPORPHYRIN IX CONTAINING FEPROTOPORPHYRIN IX CONTAINING FE
5
2
5,6,7,8-TETRAHYDROBIOPTERIN5,6,7,8-TETRAHYDROBIOPTERIN
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303