3GGV: HIV Protease, pseudo-symmetric inhibitors

PDB ID: 3GGVDownload
MMDB ID: 72914
PDB Deposition Date: 2009/3/2
Updated in MMDB: 2011/05
Experimental Method:
x-ray diffraction
Resolution: 3.09  Å
Source Organism:
Similar Structures:
Biological Unit for 3GGV: dimeric; determined by author and by software (PISA)
Molecular Components in 3GGV
Label Count Molecule
Proteins (2 molecules)
2
V-1 Protease
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
methyl [(1S)-1-{[(1R,3S,4S)-3-hydroxy-4-{[(2S)-2-(3-{[6-(1-hydroxy-1-methylethyl)pyridin-2-yl]methyl}-2-oxo-2,3-dihydro-1H-imidazol-1-yl)-3,3-dimethylbutanoyl]amino}-5-phenyl-1-(4-pyridin-2-ylbenzyl)pentyl]carbamoyl}-2,2-dimethylpropyl]carbamatemethyl [(1S)-1-{[(1R,3S,4S)-3-hydroxy-4-{[(2S)-2-(3-{[6-(1-hydroxy-1-methylethyl)pyridin-2-yl]methyl}-2-oxo-2,3-dihydro-1H-imidazol-1-yl)-3,3-dimethylbutanoyl]amino}-5-phenyl-1-(4-pyridin-2-ylbenzyl)pentyl]carbamoyl}-2,2-dimethylpropyl]carbamate
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303