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3HP5:
Crystal Structure of Human p38alpha complexed with a pyrimidopyridazinone compound
PDB ID:
3HP5
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MMDB ID:
77040
PDB Deposition Date:
2009/6/3
Updated in MMDB:
2017/11
Experimental Method:
x-ray diffraction
Resolution:
2.3 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
Download sequence data
Biological Unit for 3HP5: monomeric; determined by author and by software (PISA)
Molecular Components in 3HP5
Label
Count
Molecule
Protein (1 molecule)
A
1
Mitogen-activated Protein Kinase 14
(Gene symbol:
MAPK14
)
Chemicals and Non-standard biopolymers (3 molecules)
1
1
5-(2,6-dichlorophenyl)-2-[(2,4-difluorophenyl)sulfanyl]-6H-pyrimido[1,6-b]pyridazin-6-one
2
2
2-fluoro-4-[4-(4-fluorophenyl)-1H-pyrazol-3-yl]pyridine
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303