3ZOS: Structure of the DDR1 kinase domain in complex with ponatinib

PDB ID: 3ZOSDownload
MMDB ID: 109532
PDB Deposition Date: 2013/2/22
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 1.92  Å
Source Organism:
Similar Structures:
Biological Unit for 3ZOS: monomeric; determined by author and by software (PISA)
Molecular Components in 3ZOS
Label Count Molecule
Protein (1 molecule)
1
Epithelial Discoidin Domain-containing Receptor 1
(Gene symbol: DDR1)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
2
3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzam ide3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzam ide
2
2
1,2-ETHANEDIOL1,2-ETHANEDIOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303