4D9R: Inhibiting Alternative Pathway Complement Activation by Targeting the Exosite on Factor D

PDB ID: 4D9RDownload
MMDB ID: 97503
PDB Deposition Date: 2012/1/11
Updated in MMDB: 2023/09
Experimental Method:
x-ray diffraction
Resolution: 2.42  Å
Source Organism:
Similar Structures:
Molecular Components in 4D9R
Label Count Molecule
Proteins (6 molecules)
2
Complement Factor D
(Gene symbol: CFD)
Molecule annotation
2
FAB Light Chain
(Gene symbol: IGKC)
Molecule annotation
2
FAB Heavy Chain
(Gene symbol: IGHG1)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
2
CHLORIDE IONCHLORIDE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303