4F2A: Crystal Structure Of Cholestryl Esters Transfer Protein In Complex With Inhibitors

PDB ID: 4F2ADownload
MMDB ID: 102723
PDB Deposition Date: 2012/5/7
Updated in MMDB: 2012/11
Experimental Method:
x-ray diffraction
Resolution: 3.11  Å
Source Organism:
Similar Structures:
Biological Unit for 4F2A: monomeric; determined by author and by software (PISA)
Molecular Components in 4F2A
Label Count Molecule
Protein (1 molecule)
1
Cholesteryl Ester Transfer Protein
(Gene symbol: CETP)
Molecule annotation
Chemicals and Non-standard biopolymers (10 molecules)
1
2
N-Acetyl-D-GlucosamineN-Acetyl-D-Glucosamine
2
1
Alpha-D-MannoseAlpha-D-Mannose
3
1
Alpha-L-FucoseAlpha-L-Fucose
4
2
Cholesteryl Oleate(3beta,9beta,14beta,17alpha)-cholest-5-en-3-yl (9z)-octadec-9-enoate
5
1
1,2-Dioleoyl-Sn-Glycero-3-Phosphocholine(z,z)-4-hydroxy-n,n,n-trimethyl-10-oxo-7-[(1-oxo-9-octadecenyl)oxy]-3,5,9-trioxa-4-phosphaheptacos-18-en-1-aminium-4-oxide
6
1
Triethylene GlycolTriethylene Glycol
7
1
Chloride IonChloride Ion
8
1
(2r)-3-{[4-(4-Chloro-3-Ethylphenoxy)pyrimidin-2-Yl][3-(1,1,2,2-Tetrafluoroethoxy)benzyl]amino}-1,1,1-Trifluoropropan-2-Ol(2r)-3-{[4-(4-Chloro-3-Ethylphenoxy)pyrimidin-2-Yl][3-(1,1,2,2-Tetrafluoroethoxy)benzyl]amino}-1,1,1-Trifluoropropan-2-Ol
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303