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4JKV:
Structure of the human smoothened 7TM receptor in complex with an antitumor agent
PDB ID:
4JKV
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MMDB ID:
109459
PDB Deposition Date:
2013/3/11
Updated in MMDB:
2017/11
Experimental Method:
x-ray diffraction
Resolution:
2.45 Å
Source Organism:
synthetic construct
Similar Structures:
VAST+
Download sequence data
Biological Unit for 4JKV: dimeric; determined by author and by software (PISA)
Molecular Components in 4JKV
Label
Count
Molecule
Proteins (2 molecules)
A
B
2
Soluble Cytochrome B562, Smoothened Homolog
(Gene symbol:
SMO
)
Chemicals and Non-standard biopolymers (14 molecules)
1
2
4-fluoro-N-methyl-N-{1-[4-(1-methyl-1H-pyrazol-5-yl)phthalazin-1-yl]piperidin-4-yl}-2-(trifluoromethyl)benzamide
2
5
(2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate
3
3
OLEIC ACID
4
2
DI(HYDROXYETHYL)ETHER
5
1
TRIETHYLENE GLYCOL
6
1
TETRAETHYLENE GLYCOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303