4K33: Crystal Structure of FGF Receptor 3 (FGFR3) Kinase Domain Harboring the K650E Mutation, a Gain-of-Function Mutation Responsible for Thanatophoric Dysplasia Type II and Spermatocytic Seminoma

PDB ID: 4K33Download
MMDB ID: 113413
PDB Deposition Date: 2013/4/10
Updated in MMDB: 2016/12
Experimental Method:
x-ray diffraction
Resolution: 2.3405  Å
Source Organism:
Similar Structures:
Biological Unit for 4K33: monomeric; determined by author and by software (PISA)
Molecular Components in 4K33
Label Count Molecule
Protein (1 molecule)
1
Fibroblast Growth Factor Receptor 3
(Gene symbol: FGFR3)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTERPHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER
2
2
MAGNESIUM IONMAGNESIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303