4QNQ: Crystal Structure Analysis of full-length Bcl-XL in complex with the inhibitor ABT-263

PDB ID: 4QNQDownload
MMDB ID: 133626
PDB Deposition Date: 2014/6/18
Updated in MMDB: 2015/10
Experimental Method:
x-ray diffraction
Resolution: 2.3  Å
Source Organism:
Similar Structures:
Biological Unit for 4QNQ: dimeric; determined by author and by software (PISA)
Molecular Components in 4QNQ
Label Count Molecule
Proteins (2 molecules)
2
Bcl-2-like Protein 1
(Gene symbol: Bcl2l1)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
4
4-(4-{[2-(4-chlorophenyl)-5,5-dimethylcyclohex-1-en-1-yl]methyl}piperazin-1-yl)-N-[(4-{[(2R)-4-(morpholin-4-yl)-1-(phenylsulfanyl)butan-2-yl]amino}-3-[(trifluoromethyl)sulfonyl]phenyl)sulfonyl]benzamide4-(4-{[2-(4-chlorophenyl)-5,5-dimethylcyclohex-1-en-1-yl]methyl}piperazin-1-yl)-N-[(4-{[(2R)-4-(morpholin-4-yl)-1-(phenylsulfanyl)butan-2-yl]amino}-3-[(trifluoromethyl)sulfonyl]phenyl)sulfonyl]benzamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303